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https://www.readbyqxmd.com/read/29211884/impact-of-current-and-past-cancer-history-on-the-risk-of-cardiovascular-events-following-percutaneous-coronary-intervention-a-kumamoto-university-malignancy-and-atherosclerosis-kuma-study
#1
Noriaki Tabata, Daisuke Sueta, Eiichiro Yamamoto, Seiji Takashio, Yuichiro Arima, Satoshi Araki, Kenshi Yamanaga, Masanobu Ishii, Kenji Sakamoto, Hisanori Kanazawa, Koichiro Fujisue, Shinsuke Hanatani, Hirofumi Soejima, Seiji Hokimoto, Yasuhiro Izumiya, Sunao Kojima, Hiroshige Yamabe, Koichi Kaikita, Kenichi Tsujita
Background: As progress is made in successfully treating cancer, there is increasing need to focus on the risk and complexity of treating cardiovascular events in cancer survivors - thus, the field of onco-cardiology/cardio-oncology has emerged. We examined the differential incidence of cardiovascular events after percutaneous coronary intervention (PCI) in patients with or without cancer. Methods and Results: Participants were divided into a non-cancer group and a cancer group, which consisted of patients who were receiving or had ever received cancer treatment...
December 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29211288/pre-sintered-y-tzp-sandblasting-effect-on-surface-roughness-phase-transformation-and-y-tzp-veneer-bond-strength
#2
Carla Müller Ramos-Tonello, Bruno Freitas Trevizo, Raphaela Farias Rodrigues, Ana Paula Rodrigues Magalhães, Adilson Yoshio Furuse, Paulo Noronha Lisboa-Filho, Americo Sheitiro Tabata, Ana Flávia Sanches Borges
OBJECTIVES.: Sandblasting is a common method to try to improve the Y-TZP/veneer bond strength of dental prostheses, however, it may put stress on zirconia surfaces and could accelerate the t→m phase transformation. Y-TZP sandblasting before sintering could be an alternative to improve surface roughness and bonding strength of veneering ceramic. The aim of this study was to analyze the effect of Y-TZP pre-sintering sandblasting on surface roughness, phase transformation, and the Y-TZP/veneer shear bond strength...
November 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29199237/active-ingredients-of-hange-shashin-to-baicalelin-and-6-gingerol-inhibit-5-fluorouracil-induced-upregulation-of-cxcl1-in-the-colon-to-attenuate-diarrhea-development
#3
Hiroyasu Sakai, Shoko Tabata, Minami Kimura, Saori Yabe, Yosuke Isa, Yuki Kai, Fumiaki Sato, Tetsuro Yumoto, Kanako Miyano, Minoru Narita, Yasuhito Uezono
5-Fluorouracil (5-FU) is widely used as an anti cancer drug and is known to cause severe diarrhea. Recently we suggested that levels of chemokine (C-X-C motif) ligand 1 (CXCL1) and neutrophil recruitment in the colonic mucosa were drastically increased by the 5-FU administration in mice. Hange-shashin-to (HST) is prescribed in Japan for treat gastritis, stomatitis, and inflammatory diarrhea. We therefore examined the effects of HST and its active ingredients on 5-FU-induced CXCL1 upregulation in cultured colon tissue, and also examined the effects of HST on 5-FU-induced diarrhea development in the mouse...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29191246/munc18-1-gene-abnormalities-are-involved-in-neurodevelopmental-disorders-through-defective-cortical-architecture-during-brain-development
#4
Nanako Hamada, Ikuko Iwamoto, Hidenori Tabata, Koh-Ichi Nagata
While Munc18-1 interacts with Syntaxin1 and controls the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex to regulate presynaptic vesicle fusion in developed neurons, this molecule is likely to be involved in brain development since its gene abnormalities cause early infantile epileptic encephalopathy with suppression-burst (Ohtahara syndrome), neonatal epileptic encephalopathy and other neurodevelopmental disorders. We thus analyzed physiological significance of Munc18-1 during cortical development...
November 30, 2017: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/29186255/lepromatous-leprosy-simulating-rheumatoid-arthritis-report-of-a-neglected-disease
#5
Tatiana Cristina Pedro Cordeiro de Andrade, Tábata Yamasaki Martins, Bruna Cortinóvis Vieira, Tatiane Meira Santiago, Cleverson Teixeira Soares, Jaison Antônio Barreto
Brazil has the second largest number of leprosy cases in the world; nevertheless, late diagnosis is common. We report the case of a male patient with pain and numbness in both hands and feet for six years with positive rheumatoid factor and anticardiolipin under rheumatoid arthritis treatment for five years. Examination revealed diffuse cutaneous infiltration and leonine facies, characteristic features of lepromatous leprosy. Autoantibodies such as rheumatoid factor and anticardiolipin are markers of rheumatic autoimmune diseases, but their presence is also described in leprosy...
May 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29179715/the-role-of-health-policy-in-the-burden-of-breast-cancer-in-brazil
#6
Francisco Winter Dos Santos Figueiredo, Tábata Cristina do Carmo Almeida, Débora Terra Cardial, Érika da Silva Maciel, Fernando Luiz Affonso Fonseca, Fernando Adami
BACKGROUND: Breast cancer affects millions of women worldwide, particularly in Brazil, where public healthcare system is an important model in health organization and the cost of chronic disease has affected the economy in the first decade of the twenty-first century. The aim was to evaluate the role of health policy in the burden of breast cancer in Brazil between 2004 and 2014. METHODS: Secondary analysis was performed in 2017 with Brazilian Health Ministry official data, extracted from the Department of Informatics of the National Health System...
November 28, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29178505/expression-levels-of-taste-related-genes-in-palate-and-tongue-tip-and-involvement-of-transient-receptor-potential-subfamily-m-member-5-trpm5-in-taste-sense-in-chickens
#7
Yuta Yoshida, Fuminori Kawabata, Yuko Kawabata, Shotaro Nishimura, Shoji Tabata
The elucidation of the mechanisms underlying the taste sense of chickens will contribute to improvements in poultry feeding, because the molecular mechanism of chickens' taste sense defines the feeding behavior of chickens. Here we focused on the gene expressions in two different oral tissues of chickens - the palate, which contains many taste buds, and the tongue tip, which contains few taste buds. Using the quantitative real-time polymerase chain reaction method, we found that the molecular markers for taste buds of chickens, that is α-gustducin and vimentin, were expressed significantly highly in the palate compared to the tongue tip...
November 27, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29172071/zika-virus-infection-of-first-trimester-human-placentas-utility-of-an-explant-model-of-replication-to-evaluate-correlates-of-immune-protection-ex-vivo
#8
REVIEW
Matthew Petitt, Takako Tabata, Henry Puerta-Guardo, Eva Harris, Lenore Pereira
The emergence of congenital Zika virus (ZIKV) disease, with its devastating effects on the fetus, has prompted development of vaccines and examination of how ZIKV breaches the maternal-fetal barrier. Infection of placental and decidual tissue explants has demonstrated cell types at the uterine-placental interface susceptible to infection and suggests routes for transmission across the placenta and amniochorionic membrane. ZIKV replicates in proliferating Hofbauer cells within chorionic villi in placentas from severe congenital infection...
November 21, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/29168957/the-effects-of-introducing-tabata-interval-training-and-stability-exercises-to-school-children-as-a-school-based-intervention-program
#9
Annika Ekström, Anna Hafsteinsson Östenberg, Glenn Björklund, Marie Alricsson
Background Physical activities during leisure time as well as school hours have changed over the past few years, with adolescents being less physically active and adopting a sedentary lifestyle. Objective The overall objective of this mixed-methods study was to evaluate the feasibility of introducing a 4-min Tabata interval training into a lower secondary school context. A further aim was to evaluate the possible effects on: coordination, balance, and strength. Methods The study was conducted as an intervention study with a mixed-method approach...
November 23, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29164526/erratum-to-generation-of-induced-pluripotent-stem-cells-in-defined-three-dimensional-hydrogels
#10
Massimiliano Caiazzo, Yoji Tabata, Matthias P Lutolf
No abstract text is available yet for this article.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29159773/japan-society-of-gynecologic-oncology-guidelines-2015-for-the-treatment-of-vulvar-cancer-and-vaginal-cancer
#11
Toshiaki Saito, Tsutomu Tabata, Hitoshi Ikushima, Hiroyuki Yanai, Hironori Tashiro, Hitoshi Niikura, Takeo Minaguchi, Toshinari Muramatsu, Tsukasa Baba, Wataru Yamagami, Kazuya Ariyoshi, Kimio Ushijima, Mikio Mikami, Satoru Nagase, Masanori Kaneuchi, Nobuo Yaegashi, Yasuhiro Udagawa, Hidetaka Katabuchi
BACKGROUND: Vulvar cancer and vaginal cancer are relatively rare tumors, and there had been no established treatment principles or guidelines to treat these rare tumors in Japan. The first version of the Japan Society of Gynecologic Oncology (JSGO) guidelines for the treatment of vulvar cancer and vaginal cancer was published in 2015 in Japanese. OBJECTIVE: The JSGO committee decided to publish the English version of the JSGO guidelines worldwide, and hope it will be a useful guide to physicians in a similar situation as in Japan...
November 20, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29158186/diffusion-kurtosis-imaging-with-the-breath-hold-technique-for-staging-hepatic-fibrosis-a-preliminary-study
#12
Daisuke Yoshimaru, Toshiaki Miyati, Yuichi Suzuki, Yuhki Hamada, Nozomi Mogi, Ayumu Funaki, Ayumi Tabata, Atsuko Masunaga, Masahiko Shimada, Maki Tobari, Takayoshi Nishino
PURPOSE: To evaluate the potential of diffusion kurtosis imaging (DKI) analysis with the breath-hold technique to assess the stage or classify hepatic fibrosis. MATERIALS AND METHODS: Patients (n=67) suspected of having a disease of the hepatobiliary system examined by diffusion-weighted imaging (DWI) using a 3.0-T magnetic resonance imaging unit were enrolled in this study. To evaluate hepatic fibrosis, mean kurtosis, Mean apparent diffusion (MD) and apparent diffusion coefficient (ADC) values were compared between groups with varying fibrosis; F0-F1, F2-F3, and F4...
November 17, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29153413/an-objective-evaluation-of-nocturnal-cough-count-and-cough-pattern-in-children-with-psychogenic-cough
#13
Eri Imai, Kota Hirai, Yoshiko Mikami, Mariko Nukaga, Mayumi Enseki, Hideyuki Tabata, Masahiko Kato, Hiroyuki Mochizuki
Two patients with a chronic, barking cough were diagnosed with psychogenic cough. Using an original cough counter we studied the nocturnal cough count and pattern. While the number of coughs when awake was extremely high for both patients, the number of coughs was remarkably reduced during sleep, similar to an exacerbation of asthma. Moreover, the properties of the coughs when awake were clearly different from those of coughs during sleep. In conclusion, an objective examination using a cough counter was useful for the diagnosis, treatment and management of psychogenic cough...
November 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/29151442/effects-of-short-lasting-supramaximal-intensity-exercise-on-diet-induced-increase-in-oxygen-uptake
#14
Katsunori Tsuji, Yuzhong Xu, Xin Liu, Izumi Tabata
This study was undertaken to quantify the additional increase in diet-induced oxygen uptake after exhaustive high-intensity intermittent exercise (HIIE), consisting of 6-7 bouts of 20-sec bicycle exercise (intensity: 170% V˙O2max) with a 10-sec rest between bouts. Using a metabolic chamber, the oxygen uptake of ten men was measured from 10:30 am to 07:00 am the next day on two separate days with or without HIIE, with lunch (12:00) and supper (18:00) (Diet experiment). On two other days, the oxygen uptake of six different subjects was measured from 10:30 to 16:00 with or without HIIE, but without meals (Fasting experiment)...
November 2017: Physiological Reports
https://www.readbyqxmd.com/read/29151233/clinical-results-of-hemiarthroplasty-using-new-bipolar-cups-for-stage-3-or-lower-osteonecrosis-of-the-femoral-head-a-retrospective-study
#15
T Abe, N Kaku, T Tabata, H Tagomori, H Tsumura
PURPOSE: The aim of this study was to evaluate clinical and radiographic findings of stage 3 or lower osteonecrosis of the femoral head (ONFH) with intact acetabular cartilage in patients treated with bipolar hemiarthroplasty (BHA). METHODS: A total of 79 hips that underwent BHA for ONFH were included in this study. The average observation period was 7.6 years. Clinical results were evaluated using the Harris hip score. We performed radiographic analysis to assess the migration of the outer cup, the permanent image around the outer cup, and loosening of the stem...
November 18, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29148861/a-new-approach-for-determining-short-term-objective-prognostic-predictive-methods-for-terminal-cancer-patients-based-on-the-change-point-of-laboratory-test-values
#16
Kazuyuki Niki, Yoshiaki Okamoto, Yoshitaka Tabata, Mamiko Tsugane, Taizo Murata, Masao Mizuki, Yasushi Matsumura, Tatsuya Takagi, Etsuko Uejima
BACKGROUND: In terminal phase cancer, predicting a prognosis precisely plays an important role for patients and their families to live meaningful lives. However, there are no established short-term, objective prognostic predictive methods. OBJECTIVE: To develop simple, short-term, objective prognostic predictive methods through detecting a change point for laboratory test values. DESIGN: A retrospective chart review. SETTING/SUBJECTS: Subjects were cancer patients aged ≥16 years and discharged dead from Osaka University Hospital in 2008...
November 17, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29138841/enhanced-activated-t%C3%A2-cell-subsets-in-prostate-cancer-patients-receiving-iodine-125-low-dose-rate-prostate-brachytherapy
#17
Makoto Kubo, Takefumi Satoh, Hiromichi Ishiyama, Ken-Ichi Tabata, Hideyasu Tsumura, Shoko Komori, Masatsugu Iwamura, Shiro Baba, Kazushige Hayakawa, Toshihiko Kawamura, Fumiya Obata
Radiotherapy (RT) is one of the most important treatments for prostate cancer. Although RT can kill cancer cells through direct and indirect effects of radiation, it occasionally induces an abscopal effect whereby localized radiation treatment is associated with elimination of metastatic cancer at a distance from the irradiated area. Thus, RT may induce an effective antitumor immune response, although the mechanism involved has remained unclear. The present was designed to evaluate this effect of RT in 36 patients with prostate cancer who provided informed consent prior to enrollment in this clinical trial...
November 13, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29131541/rhombic-shaped-nanostructures-and-mechanical-properties-of-2d-dna-origami-constructed-with-different-crossover-nick-designs
#18
Zhipeng Ma, Yunfei Huang, Seongsu Park, Kentaro Kawai, Do-Nyun Kim, Yoshikazu Hirai, Toshiyuki Tsuchiya, Hirofumi Yamada, Osamu Tabata
DNA origami methods enable the fabrication of various nanostructures and nanodevices, but their effective use depends on an understanding of their structural and mechanical properties and the effects of basic structural features. Frequency-modulation atomic force microscopy is introduced to directly characterize, in aqueous solution, the crossover regions of sets of 2D DNA origami based on different crossover/nick designs. Rhombic-shaped nanostructures formed under the influence of flexible crossovers placed between DNA helices are observed in DNA origami incorporating crossovers every 3, 4, or 6 DNA turns...
November 13, 2017: Small
https://www.readbyqxmd.com/read/29114925/possible-involvement-of-a-cell-adhesion-molecule-migfilin-in-brain-development-and-pathogenesis-of-autism-spectrum-disorders
#19
Kanako Ishizuka, Hidenori Tabata, Hidenori Ito, Itaru Kushima, Mariko Noda, Akira Yoshimi, Masahide Usami, Kyota Watanabe, Mako Morikawa, Yota Uno, Takashi Okada, Daisuke Mori, Branko Aleksic, Norio Ozaki, Koh-Ichi Nagata
Migfilin, encoded by FBLIM1 at the 1p36 locus, is a multi-domain adaptor protein essential for various cellular processes such as cell morphology and migration. Small deletions and duplications at the 1p36 locus, monosomy of which results in neurodevelopmental disorders and multiple congenital anomalies, have also been identified in patients with autism spectrum disorder (ASD). However, the impact of FBLIM1, the gene within 1p36, on the pathogenesis of ASD is unknown. In this study, we performed morphological analyses of migfilin to elucidate its role in brain development...
November 8, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29113800/a-prdm8-target-gene-ebf3-regulates-multipolar-to-bipolar-transition-in-migrating-neocortical-cells
#20
Ryota Iwai, Hidenori Tabata, Mayuko Inoue, Kei-Ichiro Nomura, Tadashi Okamoto, Masamitsu Ichihashi, Koh-Ichi Nagata, Ken-Ichi Mizutani
Precise control of neuronal migration is essential for the development of the neocortex. However, the molecular mechanisms underlying neuronal migration remain largely unknown. Here we identified helix-loop-helix transcription factor Ebf3 as a Prdm8 target gene, and found that Ebf3 is a key regulator of neuronal migration via multipolar-to-bipolar transition. Ebf3 knockdown cells exhibited severe defects in the formation of leading processes and an inhibited shift to the locomotion mode. Moreover, we found that Ebf3 knockdown represses NeuroD1 transcription, and NeuroD1 overexpression partially rescued migration defects in Ebf3 knockdown cells...
November 4, 2017: Biochemical and Biophysical Research Communications
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