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Echocardiography , heart failure

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https://www.readbyqxmd.com/read/29932311/rationale-and-design-of-a-multicentre-randomized-placebo-controlled-trial-of-mirabegron-a-beta3-adrenergic-receptor-agonist-on-left-ventricular-mass-and-diastolic-function-in-patients-with-structural-heart-disease-beta3-left-ventricular-hypertrophy-beta3-lvh
#1
Anne-Catherine Pouleur, Stefan Anker, Dulce Brito, Oana Brosteanu, Dirk Hasenclever, Barbara Casadei, Frank Edelmann, Gerasimos Filippatos, Damien Gruson, Ignatios Ikonomidis, Renaud Lhommel, Masliza Mahmod, Stefan Neubauer, Alexandre Persu, Bernhard L Gerber, Stefan Piechnik, Burkert Pieske, Elisabeth Pieske-Kraigher, Fausto Pinto, Piotr Ponikowski, Michele Senni, Jean-Noël Trochu, Nancy Van Overstraeten, Rolf Wachter, Jean-Luc Balligand
AIMS: Progressive left ventricular (LV) remodelling with cardiac myocyte hypertrophy, myocardial fibrosis, and endothelial dysfunction plays a key role in the onset and progression of heart failure with preserved ejection fraction. The Beta3-LVH trial will test the hypothesis that the β3 adrenergic receptor agonist mirabegron will improve LV hypertrophy and diastolic function in patients with hypertensive structural heart disease at high risk for developing heart failure with preserved ejection fraction...
June 22, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29929991/association-of-circulating-adipokines-with-echocardiographic-measures-of-cardiac-structure-and-function-in-a-community-based-cohort
#2
Beatrice von Jeinsen, Meghan I Short, Vanessa Xanthakis, Herman Carneiro, Susan Cheng, Gary F Mitchell, Ramachandran S Vasan
BACKGROUND: Adipokines mediate cardiometabolic risk associated with obesity but their role in the pathogenesis of obesity-associated heart failure remains uncertain. We investigated the associations between circulating adipokine concentrations and echocardiographic measures in a community-based sample. METHODS AND RESULTS: We evaluated 3514 Framingham Heart Study participants (mean age 40 years, 53.8% women) who underwent routine echocardiography and had select circulating adipokines measured, ie, leptin, soluble leptin receptor, fatty acid-binding protein 4, retinol-binding protein 4, fetuin-A, and adiponectin...
June 21, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29929955/accuracy-of-a-novel-handheld-wireless-platform-for-detection-of-cardiac-dysfunction-in-anthracycline-exposed-survivors-of-childhood-cancer
#3
Saro H Armenian, Derek Rinderknecht, Kaylene Au, Lanie Lindenfeld, George Mills, Aida Siyahian, Claudia Herrera, Karla Wilson, Kalyanasundaram Venkataraman, Kristen Mascarenhas, Peyman Tavallali, Marianne Razavi, Niema Pahlevan, Jon Detterich, Smita Bhatia, Morteza Gharib
Purpose: Childhood cancer survivors are at risk for anthracycline-related cardiac dysfunction, often developing at a time when they are least engaged in long-term survivorship care. New paradigms in survivorship care and chronic disease screening are needed in this population. We compared the accuracy of a novel handheld mHealth platform (Vivio) as well as echocardiography for assessment of cardiac function [left ventricular ejection fraction (EF)] in childhood cancer survivors with cardiac magnetic resonance (CMR) imaging (reference)...
June 21, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29928642/pathophysiology-and-diagnosis-of-pulmonary-hypertension-due-to-left-heart-disease
#4
REVIEW
Athanasios Charalampopoulos, Robert Lewis, Peter Hickey, Charlotte Durrington, Charlie Elliot, Robin Condliffe, Ian Sabroe, David G Kiely
Pulmonary hypertension due to left heart disease (PH-LHD) is the most common type of pulmonary hypertension, although an accurate prevalence is challenging. PH-LHD includes PH due to systolic or diastolic left ventricular dysfunction, mitral or aortic valve disease and congenital left heart disease. In recent years a new and distinct phenotype of "combined post-capillary and pre-capillary PH," based on diastolic pulmonary gradient and pulmonary vascular resistance, has been recognized. The roles of right ventricular dysfunction and pulmonary vascular compliance in PH-LHD have also been elucidated recently and they appear to have significant clinical implications...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29928010/association-between-right-ventricle-two-and-three-dimensional-echocardiography-and-exercise-capacity-in-patients-with-reduced-left-ventricular-ejection-fraction
#5
Aleksandra Sljivic, Milena Pavlovic Kleut, Zoran Bukumiric, Vera Celic
INTRODUCTION: Echocardiography represents the most commonly performed noninvasive cardiac imaging test for patients with heart failure (HF). The aim of this study was to assess the relationship between exercise capacity parameters (peak oxygen consumption (VO2) and the minute ventilation-carbon dioxide production relationship (VE/VCO2)), two-dimensional speckle-tracking echocardiography (2D-STE) and three-dimensional echocardiography (3DE) imaging of right ventricular (RV) function in HF patients with reduced ejection fraction (EF)...
2018: PloS One
https://www.readbyqxmd.com/read/29926566/-cardiac-tamponade
#6
A Ancion, S Robinet, P Lancellotti
Cardiac tamponade is a vital emergency. It occurs when the accumulation of intra-pericardial fluid exceeds the pericardial adaptation capacity. Pericardial pressure is equalized with that of cardiac cavities and severe heart failure occurs, most often rapidly. Several clinical presentations are possible. The diagnosis is based on the assessment of pericardial effusion and its impact on the heart by echocardiography. Supportive treatments have limited effectiveness. The only emergency treatment is drainage of the pericardium by direct puncture or by surgical approach...
May 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29921383/effect-of-sildenafil-on-pulmonary-hypertension-associated-with-left-heart-failure
#7
N Wu, G Yang
This study aims to evaluate the effect of sildenafil on pulmonary hypertension (PH) associated with chronic left heart failure. Twenty patients with PH and left heart failure were divided into treatment group (10 cases, with an oral dose of sildenafil 75 mg daily for 8 weeks) and control group (10 cases, with treatment of cardiac glycosides, diuretics, angiotensin-converting enzyme inhibitor, angiotensin II receptor blocker and beta-blockers). Left ventricular systolic function (LVEF), the pulmonary artery systolic pressure (PH), the left ventricular fraction shortening (LVFS), the left atrium diameter (LAD) and the left ventricular end-diastolic diameter (LVD) were measured by echocardiography, the left ventricular mass index (LVMI) was also calculated...
May 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29916098/the-effects-of-xanthine-oxidase-inhibitor-in-patients-with-chronic-heart-failure-complicated-with-hyperuricemia-a-prospective-randomized-controlled-clinical-trial-of-topiroxostat-vs-allopurinol-study-protocol
#8
Masashi Sakuma, Shigeru Toyoda, Takuo Arikawa, Yota Koyabu, Toru Kato, Taichi Adachi, Hideaki Suwa, Jun-Ichi Narita, Koetsu Anraku, Kimihiko Ishimura, Fumitake Yamauchi, Yasunori Sato, Teruo Inoue
BACKGROUND: Hyperuricemia has a close relationship with cardiovascular diseases including heart failure. However, it is controversial whether xanthine oxidase inhibition has benefits for patients with chronic heart failure. We designed the Effect of Xanthine Oxidase Inhibitor in Chronic Heart Failure Patients Complicated with Hyperuricemia study (Excited-UA study) to compare the beneficial effects between a novel xanthine oxidoreductase inhibitor, topiroxostat, and a conventional agent, allopurinol, in patients with chronic heart failure and hyperuricemia...
June 18, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29912139/transesophageal-echocardiography-guided-epicardial-left-ventricular-lead-placement-by-video-assisted-thoracoscopic-surgery-in-nonresponders-to-biventricular-pacing-and-previous-chest-surgery
#9
Carsten Schroeder, Jane M Chung, Judith A Mackall, Ivan T Cakulev, Aaron Patel, Sunny J Patel, Brian D Hoit, Jayakumar Sahadevan
OBJECTIVE: The aim of the study was to study the feasibility, safety, and efficacy of transesophageal echocardiography-guided intraoperative left ventricular lead placement via a video-assisted thoracoscopic surgery approach in patients with failed conventional biventricular pacing. METHODS: Twelve patients who could not have the left ventricular lead placed conventionally underwent epicardial left ventricular lead placement by video-assisted thoracoscopic surgery...
June 14, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29911012/rupture-of-sinus-of-valsalva-aneurysm-into-left-atrium-in-a-patient-who-is-a-candidate-for-hepatic-transplantation
#10
Veysel Tosun, Necmettin Korucuk, Unal Guntekin
Sinus of valsalva aneurysm (SVA) is a rare cardiac disease. The most common complication of SVA is rupture into the right atrium or right ventricle. Rupture into the left chambers is very rare. Patients with ruptured SVA are likely to die of heart failure or endocarditis. We present a 29-year-old man who was hospitalized for hepatic transplantation with rupture of SVA. Transthoracic echocardiography and transesophageal echocardiography showed rupture of a noncoronary SVA into the left atrium. Mitral valve infective endocarditis developed and surgery was planned for the patient, but the patient died due to multiple organ dysfunction syndrome...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29911005/prognostic-value-of-a-tissue-doppler-index-of-systodiastolic-function-in-patients-with-asymptomatic-heart-failure
#11
Nicola Riccardo Pugliese, Iacopo Fabiani, Salvatore La Carrubba, Scipione Carerj, Lorenzo Conte, Paolo Colonna, Pio Caso, Frank Benedetto, Francesco Antonini-Canterin, Maria Francesca Romano, Rodolfo Citro, Vitantonio Di Bello
Introduction: Doppler echocardiography with early diastolic transmitral velocity (E)/early mitral annular diastolic velocity (E') ratio has been proposed as the best predictor for evaluating left ventricle (LV) filling pressure. A dimensionless index E/(E' × S') ratio (S' = systolic mitral annulus velocity) resulted in readily, reproducible, and reliable predictor of LV filling pressure. We assessed the prognostic impact of E/E' × S') in patients with asymptomatic heart failure (HF)...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29910817/treating-heart-inflammation-with-interleukin-1-blockade-in-a-case-of-erdheim-chester-disease
#12
Alessandro Tomelleri, Giulio Cavalli, Giacomo De Luca, Corrado Campochiaro, Teresa D'Aliberti, Moreno Tresoldi, Lorenzo Dagna
Pericarditis is an inflammatory heart disease, which may be idiopathic or secondary to autoimmune or auto-inflammatory diseases and often leads to severe or life-threatening complications. Colchicine and non-steroidal anti-inflammatory drugs represent the mainstay of treatment, whereas use of corticosteroids is associated with recurrence of disease flares. While effective and safe anti-inflammatory therapies remain an unmet clinical need, emerging clinical and experimental evidence points at a promising role of inhibition of the pro-inflammatory cytokine interleukin-1 (IL-1)...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29909950/-management-of-mitral-valve-stenosis-during-pregnancy-at-the-oran-university-hospital-center-about-83-cases
#13
N F Benatta, D D Batouche, M A Djazouli, S A Zelmat, T Merzouk, L Hammou
INTRODUCTION: The management of pregnancy in patients with mitral valve stenosis disease continues to pose a challenge to the clinician. OBJECTIVE: The aim of study was to evaluate the association between mitral valve stenosis and maternal and fetal out come. MATERIEL AND METHOD: Eighty-three pregnant women with mitral valve disease, followed-up from 2009 to 2012, were prospectively evaluated medical history, NYHA class assessment, ECG and echocardiography were performed during pregnancy and after delivery...
June 14, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29909737/respirophasic-desaturation-in-multivalvar-rheumatic-heart-disease
#14
Krishna Kumar Mohanan Nair, Arun Gopalakrishnan, Ajitkumar Valaparambil
A 28-year-old lady with rheumatic heart disease presented with dyspnoea and overt right heart failure and was admitted for stabilization. She had respirophasic desaturation predominantly during inspiration. Trans-oesophageal echocardiography revealed the aetiology of the same and dictated the management strategy.
June 17, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29907861/higher-plasma-leptin-levels-are-associated-with-reduced-left-ventricular-mass-and-left-ventricular-diastolic-stiffness-in-black-women-insights-from-the-genetic-epidemiology-network-of-arteriopathy-genoa-study
#15
Daisuke Kamimura, Takeki Suzuki, Wanmei Wang, Matthew deShazo, John E Hall, Michael D Winniford, Iftikhar J Kullo, Thomas H Mosley, Kenneth R Butler, Michael E Hall
Our previous experimental animal data suggest a beneficial effect of leptin on LV structure and function. We hypothesized that leptin levels are associated with lower LV mass and myocardial stiffness which are important risk factors for the development of heart failure with preserved ejection fraction (HFpEF). We evaluated 1172 blacks, in which the prevalence of HFpEF is quite high, with preserved LV ejection fraction (EF > 50%) from the Genetic Epidemiology Network of Arteriopathy Study (mean age 62...
June 15, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29905827/predictors-of-residual-tricuspid-regurgitation-after-percutaneous-closure-of-atrial-septal-defect
#16
Martina Nassif, Frank van der Kley, Mohammad Abdelghani, Deborah N Kalkman, Rianne H A C M de Bruin-Bon, Berto J Bouma, Martin J Schalij, David R Koolbergen, Jan G P Tijssen, Barbara J M Mulder, Robbert J de Winter
Aims: Functional tricuspid regurgitation (TR) associated with atrial septal defects (ASDs) is frequently present due to right-sided volume-overload. Tricuspid valve (TV) repair is often considered in candidates for surgical ASD closure, and percutaneous TV repair is currently under clinical investigation. In this study, we develop a prediction model to identify patients with residual moderate/severe TR after percutaneous ASD closure. Methods and results: In this observational study, 172 adult patients (26% male, age 49 ± 17 years) with successful percutaneous ASD closure had pre- and post-procedural echocardiography...
June 13, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29904451/thrombolysis-is-an-effective-and-safe-therapy-in-stuck-mitral-valves-with-delayed-presentation-as-well-as-hemodynamically-unstable-patients-a-single-centre-study
#17
Arun Shivajirao Bade, Shakil Sattar Ahmed Shaikh, Hemant Khemani, Gurkirat Singh, Narender Omprakash Bansal
Background: Thrombosis is a complication of prosthetic valves on oral anticoagulants which is associated with significant morbidity and mortality. A re-operation carries a substantial risk, with mortality rate from 10% to 15% in selected series, which may be 2- or 3-folds higher in critically ill patients. This study conducted in a tertiary care cardiology unit aimed to evaluate the effectiveness and safety of thrombolytic therapy in stuck mitral bileaflet heart valves. Methods: As a prospective observational study, clinical symptoms and fluoroscopy were the mainstay in diagnosis of stuck mitral valve...
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29904302/acute-heart-failure-related-to-a-large-left-atrial-myxoma
#18
Giovanni A Chiariello, Piergiorgio Bruno, Christian Colizzi, Natalia Pavone, Marialisa Nesta, Federico Cammertoni, Andrea Mazza, Alfredo Posteraro, Gianluigi Perri, Massimo Massetti
An association between atrial myxoma and left ventricular failure is rarely described, is not completely understood, and may have multiple etiologies. We present a 49-year-old man with no history of cardiovascular disease who was admitted to our hospital with pulmonary edema. He was in atrial fibrillation with rapid ventricular response. Echocardiography showed a 10.5-cm left atrial myxoma, which had been asymptomatic until the onset of congestive heart failure in the presence of severe left ventricular systolic dysfunction...
July 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29903518/3d-echocardiography-derived-right-ventricular-function-is-associated-with-right-ventricular-failure-and-mid-term-survival-after-left-ventricular-assist-device-implantation
#19
Harry Magunia, Clemens Dietrich, Harald F Langer, David Schibilsky, Christian Schlensak, Peter Rosenberger, Martina Nowak-Machen
BACKGROUND: Right heart failure remains a major cause of morbidity and mortality after left ventricular assist device (LVAD) implantation. Multiple 2D echocardiography derived parameters are associated with right ventricular failure (RV failure), but none of them has been proven to be a reliable predictor to date. We hypothesized that novel 3D-echocardiography (3DE) based parameters are associated with RV failure and predict long term outcome in patients undergoing LVAD implantation. METHODS: This single-center study retrospectively enrolled 26 patients undergoing continuous-flow LVAD implantation...
June 8, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29901286/echocardiographic-predictors-of-change-in-renal-function-with-intravenous-diuresis-for-decompensated-heart-failure
#20
Stephen A Gannon, Kenneth J Mukamal, James D Chang
AIMS: The aim of this study was to identify echocardiographic predictors of improved or worsening renal function during intravenous diuresis for decompensated heart failure. Secondary aim included defining the incidence and clinical risk factors for acute changes in renal function with decongestion. METHODS AND RESULTS: A retrospective review of 363 patients admitted to a single centre for decompensated heart failure who underwent intravenous diuresis and transthoracic echocardiography was conducted...
June 14, 2018: ESC Heart Failure
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