keyword
MENU ▼
Read by QxMD icon Read
search

Cingulum

keyword
https://www.readbyqxmd.com/read/28631869/lateralized-hippocampal-volume-increase-following-high-frequency-left-prefrontal-repetitive-transcranial-magnetic-stimulation-in-patients-with-major-depression
#1
Shunsuke Hayasaka, Motoaki Nakamura, Yoshihiro Noda, Takuji Izuno, Takashi Saeki, Hideo Iwanari, Yoshio Hirayasu
AIM: Repetitive transcranial magnetic stimulation (rTMS) has been applied as a treatment for patients with treatment-resistant depression in recent years, and a large body of evidence has demonstrated its therapeutic efficacy through stimulating neuronal plasticity. The aim of this study was to investigate structural alterations in the hippocampus (HIPP) and amygdala (AM) following conventional rTMS in patients with depression. METHODS: Twenty-eight patients with depression underwent 10 daily 20-Hz left prefrontal rTMS over 2 weeks...
June 20, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28631553/administration-of-progesterone-throughout-pregnancy-increases-maternal-steroids-without-adverse-effect-on-mature-oligodendrocyte-immunostaining-in-the-guinea-pig
#2
Julia C Shaw, Hannah K Palliser, Kerrin Palazzi, Jonathan J Hirst
Progesterone is administered to pregnant women at risk of premature labor, despite systematic reviews showing conflicting outcomes regarding its use, highlighting doubt over the effectiveness of the therapy. Progesterone can be rapidly metabolized into a number of steroids, but to date, there has been a lack of investigation into the fetal steroid profiles following administration and whether this impacts fetal neurodevelopment. The objective of this study was to determine the effect of progesterone treatment on allopregnanolone and cortisol levels in the fetus and on a marker of myelination in the fetal brain...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28609669/sex-differences-in-associations-between-white-matter-microstructure-and-gonadal-hormones-in-children-and-adolescents-with-prenatal-alcohol-exposure
#3
K A Uban, M M Herting, J R Wozniak, E R Sowell
Despite accumulating evidence from animal models demonstrating that prenatal alcohol exposure (PAE) results in life-long neuroendocrine dysregulation, very little is known on this topic among humans with fetal alcohol spectrum disorders (FASD). We expected that alterations in gonadal hormones might interfere with the typical development of white matter (WM) myelination, and in a sex-dependent manner, in human adolescents with FASD. In order to investigate this hypothesis, we used diffusion tensor imaging (DTI) to assess: 1) whether or not sex moderates the impact of PAE on WM microstructure; and 2) how gonadal hormones relate to alterations in WM microstructure in children and adolescents affected by PAE...
May 26, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28600739/association-of-longitudinal-white-matter-degeneration-and-cerebrospinal-fluid-biomarkers-of-neurodegeneration-inflammation-and-alzheimer-s-disease-in-late-middle-aged-adults
#4
Annie M Racine, Andrew P Merluzzi, Nagesh Adluru, Derek Norton, Rebecca L Koscik, Lindsay R Clark, Sara E Berman, Christopher R Nicholas, Sanjay Asthana, Andrew L Alexander, Kaj Blennow, Henrik Zetterberg, Won Hwa Kim, Vikas Singh, Cynthia M Carlsson, Barbara B Bendlin, Sterling C Johnson
Alzheimer's disease (AD) is characterized by substantial neurodegeneration, including both cortical atrophy and loss of underlying white matter fiber tracts. Understanding longitudinal alterations to white matter may provide new insights into trajectories of brain change in both healthy aging and AD, and fluid biomarkers may be particularly useful in this effort. To examine this, 151 late-middle-aged participants enriched with risk for AD with at least one lumbar puncture and two diffusion tensor imaging (DTI) scans were selected for analysis from two large observational and longitudinally followed cohorts...
June 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28596117/disrupted-white-matter-structural-networks-in-healthy-older-adults-apoe-%C3%AE%C2%B54-carriers-an-international-multicenter-dti-study
#5
Enrica Cavedo, Simone Lista, Katrine Rojkova, Patrizia Andrea Chiesa, Marion Houot, Katharina Brueggen, Janusch Blautzik, Arun L W Bokde, Bruno Dubois, Frederik Barkhof, Petra J W Pouwels, Stefan Teipel, Harald Hampel
The ε4 allelic variant of the Apolipoprotein E gene (APOE ε4) is the best-established genetic risk factor for late-onset Alzheimer's disease (AD). White matter (WM) microstructural damages measured with Diffusion Tensor Imaging (DTI) represent an early sign of fiber tract disconnection in AD. We examined the impact of APOEε4 on WM microstructure in elderly individuals from the multicenter European DTI Study on Dementia. Voxelwise statistical analysis of Fractional anisotropy (FA), mean diffusivity, radial and axial diffusivity (MD, radD and axD respectively) was carried out using Tract-Based Spatial Statistics...
June 5, 2017: Neuroscience
https://www.readbyqxmd.com/read/28590514/altered-white-matter-microarchitecture-in-the-cingulum-bundle-in-women-with-primary-dysmenorrhea-a-tract-based-analysis-study
#6
Jixin Liu, Hongjuan Liu, Junya Mu, Qing Xu, Tao Chen, Wanghuan Dun, Jing Yang, Jie Tian, Li Hu, Ming Zhang
Primary dysmenorrhea (PD), as characterized by painful menstrual cramps without organic causes, is associated with central sensitization and brain function changes. Previous studies showed the integrated role of the default mode network (DMN) in the pain connectome and its key contribution on how an individual perceives and copes with pain disorders. Here, we aimed to investigate whether the cingulum bundle connecting hub regions of the DMN was disrupted in young women with PD. Diffusion tensor imaging was obtained in 41 PD patients and 41 matched healthy controls (HC) during their periovulatory phase...
June 7, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28583034/aging-related-microstructural-alterations-along-the-length-of-the-cingulum-bundle
#7
Francesca Sibilia, Elizabeth Grace Kehoe, Dervla Farrell, Christian Kerskens, Desmond O'Neill, Jonathan Paul McNulty, Paul Gerald Mullins, Arun Bokde
The aim of this study was to investigate the aging-related structural changes of the cingulum, one of the major components of the limbic network, which has a critical role in emotion, attention and memory. 35 healthy young adults (22.3 ± 2.7 years) and 33 healthy older adults (69.5 ± 3.5 years) were recruited. Diffusion weighted imaging data were acquired with a b-value = 2000 s/mm2, 61 diffusion directions and 4 non-weighted images. The fiber directions in each voxel were based on the constrained spherical deconvolution (CSD) model...
June 5, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28575645/tesc-gene-regulating-genetic-variant-rs7294919-affects-hippocampal-subfield-volumes-and-parahippocampal-cingulum-white-matter-integrity-in-major-depressive-disorder
#8
Kyu-Man Han, Eunsoo Won, June Kang, Sunyoung Choi, Aram Kim, Min-Soo Lee, Woo-Suk Tae, Byung-Joo Ham
Two recent genome-wide association studies have suggested that rs7294919 is associated with changes in hippocampal volume. rs7294919 regulates the transcriptional products of the TESC gene, which is involved in neuronal proliferation and differentiation. We investigated the interactive effect of rs7294919 and major depressive disorder (MDD) on the volume of the hippocampal subfields and the integrity of the parahippocampal cingulum (PHC). We also investigated the correlation of these structural changes with the DNA methylation status of rs7294919...
October 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28570516/fiber-connections-of-the-supplementary-motor-area-revisited-methodology-of-fiber-dissection-dti-and-three-dimensional-documentation
#9
Baran Bozkurt, Kaan Yagmurlu, Erik H Middlebrooks, Zuzan Cayci, Orhun M Cevik, Ali Karadag, Sean Moen, Necmettin Tanriover, Andrew W Grande
The purpose of this study is to show the methodology for the examination of the white matter connections of the supplementary motor area (SMA) complex (pre-SMA and SMA proper) using a combination of fiber dissection techniques on cadaveric specimens and magnetic resonance (MR) tractography. The protocol will also describe the procedure for a white matter dissection of a human brain, diffusion tensor tractography imaging, and three-dimensional documentation. The fiber dissections on human brains and the 3D documentation were performed at the University of Minnesota, Microsurgery and Neuroanatomy Laboratory, Department of Neurosurgery...
May 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28567010/the-what-the-when-and-the-whether-of-intentional-action-in-the-brain-a-meta-analytical-review
#10
Laura Zapparoli, Silvia Seghezzi, Eraldo Paulesu
In their attempt to define discrete subcomponents of intentionality, Brass and Haggard (2008) proposed their What, When, and Whether model (www-model) which postulates that the content, the timing and the possibility of generating an action can be partially independent both at the cognitive level and at the level of their neural implementation. The original proposal was based on a limited number of studies, which were reviewed with a discursive approach. To assess whether the model stands in front of the more recently published data, we performed a systematic review of the literature with a meta-analytic method based on a hierarchical clustering (HC) algorithm...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28552181/white-matter-integrity-on-dti-and-the-pathologic-staging-of-alzheimer-s-disease
#11
Kejal Kantarci, Melissa E Murray, Christopher G Schwarz, Robert I Reid, Scott A Przybelski, Timothy Lesnick, Samantha M Zuk, Mekala R Raman, Matthew L Senjem, Jeffrey L Gunter, Bradley F Boeve, David S Knopman, Joseph E Parisi, Ronald C Petersen, Clifford R Jack, Dennis W Dickson
Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged Alzheimer's disease (AD) patients (n = 46). Patients with antemortem DTI studies and a range of AD pathology at autopsy were included. Patients with a high neurofibrillary tangle (NFT) stage (Braak IV-VI) had significantly elevated mean diffusivity (MD) in the crus of fornix and ventral cingulum tracts, precuneus, and entorhinal white matter on voxel-based analysis after adjusting for age and time from MRI to death (p < 0...
May 4, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28546056/glutamate-in-dorsolateral-prefrontal-cortex-and-auditory-verbal-hallucinations-in-patients-with-schizophrenia-a-1-h-mrs-study
#12
Branislava Ćurčić-Blake, Leonie Bais, Anita Sibeijn-Kuiper, Hendrika Maria Pijnenborg, Henderikus Knegtering, Edith Liemburg, André Aleman
PURPOSE: Glutamatergic models of psychosis propose that dysfunction of N-methyl-d-aspartate (NMDA) receptors, and associated excess of glutamate, may underlie psychotic experiences in people with schizophrenia. However, little is known about the specific relation between glutamate and auditory verbal hallucinations (AVH) in patients with psychosis. In this study, levels of glutamate+glutamine (Glx) in the left lateral prefrontal lobe were determined using proton magnetic resonance spectroscopy ((1)H MRS) to calculate their association with AVH...
May 22, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28527525/age-related-white-matter-integrity-differences-in-oldest-old-without-dementia
#13
Ilana J Bennett, Dana E Greenia, Pauline Maillard, S Ahmad Sajjadi, Charles DeCarli, Maria M Corrada, Claudia H Kawas
Aging is known to have deleterious effects on cerebral white matter, yet little is known about these white matter alterations in advanced age. In this study, 94 oldest-old adults without dementia (90-103 years) underwent diffusion tensor imaging to assess relationships between chronological age and multiple measures of integrity in 18 white matter regions across the brain. Results revealed significant age-related declines in integrity in regions previously identified as being sensitive to aging in younger-old adults (corpus callosum, fornix, cingulum, external capsule)...
April 26, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28509342/morphological-and-molecular-characterization-of-bysmatrum-subsalsum-dinophyceae-from-the-western-mediterranean-sea-reveals-the-existence-of-cryptic-species-1
#14
Sílvia Anglès, Albert Reñé, Esther Garcés, Antonella Lugliè, Nicola Sechi, Jordi Camp, Cecilia Teodora Satta
Bysmatrum subsalsum is a cosmopolitan dinoflagellate species that inhabits marine and transitional habitats. Despite its wide distribution, information on the morphological variability, phylogeny and ecology of B. subsalsum is scarce. In this study, we provide morphological and molecular data on B. subsalsum strains and wild cells from different locations in the Mediterranean Basin. The dynamics of cell abundances and the associated environmental conditions during a field bloom are also described. Genetic sequences of B...
May 16, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/28506483/cortical-and-subcortical-functional-neuroanatomy-for-low-grade-glioma-surgery
#15
REVIEW
L Chenin, M Lefranc, S Velut, P Foulon, E Havet, J Peltier
Knowledge of the encephalon anatomy is crucial for neurosurgical practice, especially the main cortical functional structures and their connections. General organisation of the encephalon is presented with frontal, parietal, occipital, temporal, limbic and insular lobes and their Brodmann correspondence. Secondly, subcortical anatomy will be presented with main white matter fasciculi in three separated categories: association, commissural and projection fibers. Main association fibers are inferior occipitofrontal fasciculus, superior longitudinal fasciculus, arcuate fasciculus, inferior longitudinal fasciculus, uncinate fasciculus, and cingulum...
May 12, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28500358/injury-prediction-and-vulnerability-assessment-using-strain-and-susceptibility-measures-of-the-deep-white-matter
#16
Wei Zhao, Yunliang Cai, Zhigang Li, Songbai Ji
Reliable prediction and diagnosis of concussion is important for its effective clinical management. Previous model-based studies largely employ peak responses from a single element in a pre-selected anatomical region of interest (ROI) and utilize a single training dataset for injury prediction. A more systematic and rigorous approach is necessary to scrutinize the entire white matter (WM) ROIs as well as ROI-constrained neural tracts. To this end, we evaluated injury prediction performances of the 50 deep WM regions using predictor variables based on strains obtained from simulating the 58 reconstructed American National Football League head impacts...
May 12, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28498605/brain-structural-connectivity-and-context-dependent-extinction-memory
#17
Andrea Hermann, Rudolf Stark, Carlo R Blecker, Mohammed R Milad, Christian J Merz
BACKGROUND: Extinction of conditioned fear represents an important mechanism in the treatment of anxiety disorders. Return of fear after successful extinction or exposure therapy in patients with anxiety disorders might be linked to poor temporal or contextual generalization of extinction due to individual differences in brain structural connectivity. The goal of this magnetic resonance imaging study was therefore to investigate the association of context-dependent extinction recall with brain structural connectivity...
May 12, 2017: Hippocampus
https://www.readbyqxmd.com/read/28496183/everyday-cognition-scales-are-related-to-cognitive-function-in-the-early-stage-of-probable-alzheimer-s-disease-and-fdg-pet-findings
#18
Jung-Lung Hsu, Wen-Chuin Hsu, Chiung-Chih Chang, Kun-Ju Lin, Ing-Tsung Hsiao, Yen-Chun Fan, Chyi-Huey Bai
We applied the Everyday Cognition (ECog) scale in normal aging adults and patients with Alzheimer's disease (AD) to investigate associations between neuropsychological tests and neuroimaging markers. A total of 160 normal aging adults and 40 patients with the early stage of probable AD were included. Neuropsychological performance was assessed using the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Assessment Battery (CERAD-NAB). (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) scans were used to measure AD-related hypometabolism...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28484418/blast-exposure-white-matter-integrity-and-cognitive-function-in-iraq-and-afghanistan-combat-veterans
#19
Iliyan Ivanov, Corey Fernandez, Effie M Mitsis, Dara L Dickstein, Edmund Wong, Cheuk Y Tang, Jessie Simantov, Charlene Bang, Erin Moshier, Mary Sano, Gregory A Elder, Erin A Hazlett
The long-term effects of blast exposure are a major health concern for combat veterans returning from the recent conflicts in Iraq and Afghanistan. We used an optimized diffusion tensor imaging tractography algorithm to assess white matter (WM) fractional anisotropy (FA) in blast-exposed Iraq and Afghanistan veterans (n = 40) scanned on average 3.7 years after deployment/trauma exposure. Veterans diagnosed with a blast-related mild traumatic brain injury (mTBI) were compared to combat veterans with blast exposure but no TBI diagnosis...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28482427/-correlation-between-the-clinical-symptoms-and-the-activation-pattern-of-brain-neurons-in-patients-with-obsessive-compulsive-disorder
#20
Q H Niu, J L Cheng, X Q Song, L Yang, C Y Chu, H Liu, L F Zhang, Y Li, Y H Li
Objective: To explore the correlation between clinical symptoms of patients with obsessive-compulsive disorder (OCD) and the activation pattern of brain neurons at resting. Methods: A total of 26 patients diagnosed with fist-episode OCD were selected and underwent functional magnetic resonance imaging (fMRI) scanning at resting state. The fMRI data were processed by statistical parametric mapping (SPM8), Data Processing Assistant for Resting-State fMRI Analysis Toolkit (DPARSFA), and Resting State fMRI Data Analysis Toolkit (REST) software...
May 9, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
keyword
keyword
30878
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"