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https://www.readbyqxmd.com/read/29055236/the-importance-of-academic-literacy-for-undergraduate-nursing-students-and-its-relationship-to-future-professional-clinical-practice-a-systematic-review
#1
REVIEW
Diana Jefferies, Stephen McNally, Katriona Roberts, Anna Wallace, Annette Stunden, Suzanne D'Souza, Paul Glew
OBJECTIVES: This systematic review was designed to assess the importance of academic literacy for undergraduate nursing students and its relationship to future professional clinical practice. It aimed to explore the link between academic literacy and writing in an undergraduate nursing degree and the development of critical thinking skills for their future professional clinical practice. DESIGN: A systematic review of qualitative studies and expert opinion publications...
October 5, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29055153/defining-the-actinic-keratosis-field-a-literature-review-and-discussion
#2
REVIEW
I Figueras Nart, R Cerio, T Dirschka, B Dréno, J T Lear, G Pellacani, K Peris, A Ruiz de Casas
BACKGROUND: Despite the chronic and increasingly prevalent nature of actinic keratosis (AK) and existing evidence supporting assessment of the entire cancerization field during clinical management, a standardized definition of the AK field to aid in the understanding and characterization of the disease is lacking. OBJECTIVES: The objective of this review is to present and appraise the available evidence describing the AK cancerization field, with the aim of determining a precise definition of the AK field in terms of its molecular (including genetic and immunological), histological, and clinical characteristics...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29054747/u-s-army-physical-demands-study-identification-and-validation-of-the-physically-demanding-tasks-of-combat-arms-occupations
#3
Marilyn A Sharp, Bruce S Cohen, Michael W Boye, Stephen A Foulis, Jan E Redmond, Kathleen Larcom, Jay R Hydren, Deborah L Gebhardt, Maria C Canino, Bradley J Warr, Edward J Zambraski
OBJECTIVES: In 2013, the U.S. Army began developing physical tests to predict a recruit's ability to perform the critical, physically demanding tasks (CPDTs) of combat arms jobs previously not open to women. The purpose of this paper is to describe the methodology and results of analyses of the accuracy and inclusiveness of the critical physically demanding task list. While the job analysis included seven combat arms jobs, only data from the 19D Cavalry Scout occupation are presented as the process was similar for all seven jobs...
October 5, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29054739/engagement-and-role-of-surgical-trainees-in-global-surgery-consensus-statement-and-recommendations-from-the-association-of-surgeons-in-training
#4
EDITORIAL
Helen M Mohan, Edward Fitzgerald, Vimal Gokani, Paul Sutton, Rhiannon Harries, Robert Bethune, Frank D McDermott
BACKGROUND: There is a wide chasm in access to essential and emergency surgery between high and low/middle income countries (LMICs). Surgeons worldwide are integral to solutions needed to address this imbalance. Involving surgical trainees, who represent the future of surgery, is vital to this endeavour. The Association of Surgeons in Training (ASiT) is an independent charity that support surgical trainees of all ten surgical specialties in the UK and Ireland. ASiT convened a consensus meeting at the ASiT conference in Liverpool 2016 to discuss trainee engagement with global surgery, including potential barriers and solutions...
October 17, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29053938/development-of-a-nanogel-based-nasal-vaccine-as-a-novel-antigen-delivery-system
#5
Rika Nakahashi-Ouchida, Yoshikazu Yuki, Hiroshi Kiyono
Nasal vaccination is one of the most effective immunization methods because it can induce effective antigen-specific immune responses not only at the mucosal site of administration but also at distant mucosal surfaces, as well as in the systemic compartment. Based on this advantage, many nasal vaccines are being developed and some have been licensed and marketed for clinical use. However, some have been withdrawn because of unacceptable adverse events such as inactivated influenza vaccine administrated with a heat-labile enterotoxin of Escherichia coli as an adjuvant...
October 20, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/29053927/safety-of-pharmacotherapy-options-for-bulimia-nervosa-and-binge-eating-disorder
#6
Nicholas T Bello, Bryn L Yeomans
Eating disorders represent a set of psychiatric illnesses with lifelong complications and high relapse rates. Individuals with eating disorders are often stigmatized and clinicians have a limited set of treatments options. Pharmacotherapy has the potential to improve long term compliance and patient commitment to treatment for eating disorders. Areas Covered: This review will examine the efficacy and safety profile of the FDA-approved medications for the treatment of bulimia nervosa (BN) and binge eating disorder (BED)...
October 20, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29053504/anesthesia-and-analgesia-practice-pathway-options-for-total-knee-arthroplasty-an-evidence-based-review-by-the-american-and-european-societies-of-regional-anesthesia-and-pain-medicine
#7
Sandra L Kopp, Jens Børglum, Asokumar Buvanendran, Terese T Horlocker, Brian M Ilfeld, Stavros G Memtsoudis, Joseph M Neal, Narinder Rawal, Jessica T Wegener
In 2014, the American Society of Regional Anesthesia and Pain Medicine in collaboration with the European Society of Regional Anaesthesia and Pain Therapy convened a group of experts to compare pathways for anesthetic and analgesic management for patients undergoing total knee arthroplasty in North America and Europe and to develop a practice pathway. This review is intended to be an analysis of the current literature to assist individuals and institutions in designing a pathway for total knee arthroplasty that is based on existing evidence and expert recommendation and may be customized according to individual settings...
November 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29053394/vedroprevir-in-the-management-of-hepatitis-c-virus-infection
#8
Ameer Abutaleb, Shyamasundaran Kottilil
Introduction Hepatitis C Virus (HCV) is a chronic infection of the liver and the leading cause of liver failure and liver transplantation worldwide. While prior HCV therapies were prolonged and had variable success rates, the advent of direct-acting antivirals (DAAs) has dramatically improved HCV therapy with minimal side effects, shorter treatment durations, and higher cure rates. Areas covered In this paper, we review the literature discussing the use of Vedroprevir (GS-9451) in treatment of HCV in a variety of patient populations...
October 20, 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29053063/a-patent-review-of-monoacylglycerol-lipase-magl-inhibitors-2013-2017
#9
Carlotta Granchi, Isabella Caligiuri, Filippo Minutolo, Flavio Rizzolio, Tiziano Tuccinardi
Monoacylglycerol lipase is a serine hydrolase that plays a major role in the degradation of the endocannabinoid 2-arachidonoylglycerol. Because of this key role, selective inactivation of MAGL represents an interesting approach to obtain desirable effects in several diseases. Furthermore, MAGL is upregulated in cancer cells and primary tumors and its inhibition in aggressive breast, ovarian, and melanoma cancer cells impairs cell migration, invasiveness, and tumorigenicity. Areas covered: This review covers patent literature on MAGL inhibitors and their applications published from 2013 to 2017...
October 20, 2017: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/29052272/ethical-issues-in-palliative-care-for-nursing-homes-development-and-testing-of-a-survey-instrument
#10
Deborah H L Preshaw, Dorry Mclaughlin, Kevin Brazil
AIM: To develop and psychometrically assess a survey instrument identifying ethical issues during palliative care provision in nursing homes. BACKGROUND: Registered nurses (RNs) and healthcare assistants (HCAs) have reported ethical issues in everyday palliative care provision. Identifying these issues provides evidence to inform practice development to support healthcare workers. DESIGN: Cross-sectional survey of RNs and HCAs in nursing homes in one region of the United Kingdom (UK) METHOD: A survey instrument, "Ethical issues in Palliative Care for Nursing homes," (EPiCNH) was developed through the findings of qualitative interviews with RNs and HCAs in nursing homes and a literature review...
October 20, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29050840/recommendations-for-the-use-of-methotrexate-in-psoriatic-arthritis
#11
Juan D Cañete, Rafael Ariza-Ariza, Sagrario Bustabad, Concepción Delgado, Cristina Fernández-Carballido, José Francisco García Llorente, Estíbaliz Loza, Carlos Montilla, Antonio Naranjo, José A Pinto, Rubén Queiro, Julio Ramírez, Jesús Tornero-Molina
OBJECTIVES: To develop recommendations for the management of methotrexate (MTX) in psoriatic arthritis (PsA), based on best evidence and experience. METHODS: A group of 12 experts on MTX use was selected. The coordinators formulated 14 questions about the use of MTX in PsA patients (indications, efficacy, safety and cost-effectiveness). A systematic review was conducted to answer the questions. Using this information, inclusion and exclusion criteria were established, as were the search strategies (Medline, EMBASE and the Cochrane Library were searched)...
October 16, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/29050521/glutamate-receptor-antagonists-with-the-potential-for-migraine-treatment
#12
Anna Ferrari, Cecilia Rustichelli, Carlo Baraldi
Preclinical, clinical, and other (e.g., genetic) evidence support the concept that migraine susceptibility may at least partially result from a glutamatergic system disorder. Therefore, the receptors of the glutamatergic system are considered relatively new targets for investigational drugs to treat migraine. Investigational and established glutamate receptor antagonists (GluRAs) have been shown to possess antinociceptive properties in preclinical models of trigeminovascular nociception and have been evaluated in clinical trials...
October 19, 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29050497/simoctocog-alfa-for-the-treatment-of-hemophilia-a
#13
Massimo Morfini
Hemophilia A is the most frequent inherited bleeding disorder and most challenging coagulation disorder. To combat this, a number of new improved rFVIII/IX concentrates have recently been approved. Some of them are derived from protein fusion biotechnology or pegylation to extend their half-life (HL). However, prophylaxis has become a standard of care to prevent arthropathy in hemophiliacs though the need of frequent venipunctures is a major obstacle to primary prophylaxis. The new Extended Half-Life (EHL) rFIX concentrates allow increased intervals, while the improved HL of new rFVIII was moderate...
October 20, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/29049621/autonomic-nervous-system-responses-to-hearing-related-demand-and-evaluative-threat
#14
Carol L Mackersie, Lucia Kearney
Purpose: This paper consists of 2 parts. The purpose of Part 1 was to review the potential influence of internal (person-related) factors on listening effort. The purpose of Part 2 was to present, in support of Part 1, preliminary data illustrating the interactive effects of an external factor (task demand) and an internal factor (evaluative threat) on autonomic nervous system measures. Method: For Part 1, we provided a brief narrative review of motivation and stress as modulators of listening effort...
October 12, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29049055/oxidized-regenerated-cellulose-collagen-dressings-review-of-evidence-and-recommendations
#15
Stephanie Wu, Andrew J Applewhite, Jeffrey Niezgoda, Robert Snyder, Jayesh Shah, Breda Cullen, Gregory Schultz, Janis Harrison, Rosemary Hill, Melania Howell, Marcus Speyrer, Howard Utra, Jean de Leon, Wayne Lee, Terry Treadwell
OBJECTIVE: Healthcare systems are being challenged to manage increasing numbers of nonhealing wounds. Wound dressings are one of the first lines of defense in wound management, and numerous options exist. The oxidized regenerated cellulose (ORC)/collagen dressing may offer healthcare providers a robust and cost-effective tool for use in a variety of wounds. DESIGN: A multidisciplinary panel meeting was convened to discuss the use of ORC/collagen dressings in wound care and provide practice recommendations...
November 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29049050/an-update-on-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#16
Danielle E Range, Xiaoyin S Jiang
PURPOSE OF REVIEW: Noninvasive encapsulated follicular variant of papillary thyroid carcinoma (PTC) has been established in the literature as a clinically indolent tumor. Despite this, it was traditionally treated like all other PTCs. In an attempt to reduce overtreatment of this entity, a panel of experts reclassified this entity as noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP). This reclassification has led to a flurry of literature elucidating the molecular, cytologic and clinical parameters of this 'new' entity and the implications for patient management...
October 18, 2017: Current Opinion in Oncology
https://www.readbyqxmd.com/read/29048948/the-spectrum-of-sickle-hemoglobin-related-nephropathy-from-sickle-cell-disease-to-sickle-trait
#17
Rakhi P Naik, Vimal K Derebail
Renal dysfunction is among the most common complication of sickle cell disease (SCD), from hyposthenuria in children to progression to overt chronic kidney disease (CKD) in young adults. Emerging evidence now suggests that sickle hemoglobin-related nephropathy extends to individuals with sickle cell trait (SCT). Areas covered: This review will highlight the pathophysiology, epidemiology, and management recommendations for sickle nephropathy in both SCD and SCT. In addition, it will focus on the major demographic and genetic modifiers of renal disease in sickling hemoglobinopathies...
October 19, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/29048936/computed-tomography-in-hypersensitivity-pneumonitis-main-findings-differential-diagnosis-and-pitfalls
#18
Olívia Meira Dias, Bruno Guedes Baldi, Francesca Pennati, Andrea Aliverti, Rodrigo Caruso Chate, Márcio Valente Yamada Sawamura, Carlos Roberto Ribeiro de Carvalho, André Luis Pereira de Albuquerque
Hypersensitivity pneumonitis (HP) is a disease with variable clinical presentation in which inflammation in the lung parenchyma is caused by the inhalation of specific organic antigens or low molecular weight substances in genetically susceptible individuals. Alterations of the acute, subacute and chronic forms may eventually overlap, and the diagnosis based on temporality and presence of fibrosis (acute/inflammatory HP vs. chronic HP) seems to be more feasible and useful in clinical practice. Differential diagnosis of chronic HP with other interstitial fibrotic diseases is challenging due to the overlap of the clinical history, and the functional and imaging findings of these pathologies in the terminal stages...
October 19, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29048935/chimeric-antigen-receptor-t-cell-therapy-for-solid-tumors-require-new-clinical-regimens
#19
Jinjing Xu, Kang Tian, Haixu Zhang, Liantao Li, Hongyan Liu, Jingjie Liu, Qing Zhang, Junnian Zheng
Chimeric antigen receptor modified T cell (CAR-T) therapy has achieved encouraging breakthroughs in the treatment of hematological malignancies. Nevertheless, this success has not yet been extrapolated to solid tumors. This review focuses on new clinical regimens that could improve the therapeutic efficacy of CAR-T in solid tumors. Areas covered: Herein, the authors reviewed recent clinical trials using CAR-T therapies for the treatment of solid tumors. Specifically, this review covered the following areas: (1) the current status of CAR-T cells in the treatment of solid tumors; (2) the major factors constraining the efficacy of CAR-T cells in solid tumors; and (3) opinions regarding the future of CAR-T as a treatment for solid tumors...
October 19, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29048350/who-environmental-noise-guidelines-for-the-european-region-a-systematic-review-on-environmental-noise-and-adverse-birth-outcomes
#20
REVIEW
Mark J Nieuwenhuijsen, Gordana Ristovska, Payam Dadvand
Introduction: Three recent systematic reviews suggested a relationship between noise exposure and adverse birth outcomes. The aim of this review was to evaluate the evidence for the World Health Organization (WHO) noise guidelines and conduct an updated systematic review of environmental noise, specifically aircraft and road traffic noise and birth outcomes, such as preterm birth, low birth weight, being small for gestational age and congenital malformations. Materials and methods: We reviewed again all the papers on environmental noise and birth outcomes included in the previous three systematic reviews and conducted a systematic search on noise and birth outcomes to update previous reviews...
October 19, 2017: International Journal of Environmental Research and Public Health
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