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https://www.readbyqxmd.com/read/27926690/changes-of-blood-pressure-patterns-and-target-organ-damage-in-patients-with-chronic-kidney-disease-results-of-the-aprodite-2-study
#1
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Eunjeong Kang, Young Rim Song, Yon Su Kim, Sung Gyun Kim
OBJECTIVE: Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern changes in hypertensive patients with CKD and their effects on target organ damages. METHODS: We recruited 378 hypertensive CKD patients from four centers in Korea. The patients underwent clinic and ambulatory BP monitoring at the time of enrollment and 1 year later. RESULTS: The BP control states at the two time points were as follows: true controlled (16...
December 6, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27926638/determining-optimal-route-of-hysterectomy-for-benign-indications-clinical-decision-tree-algorithm
#2
Jennifer J Schmitt, Daniel A Carranza Leon, John A Occhino, Amy L Weaver, Sean C Dowdy, Jamie N Bakkum-Gamez, Kalyan S Pasupathy, John B Gebhart
OBJECTIVE: To evaluate practice change after initiation of a robotic surgery program using a clinical algorithm to determine the optimal surgical approach to benign hysterectomy. METHODS: A retrospective postrobot cohort of benign hysterectomies (2009-2013) was identified and the expected surgical route was determined from an algorithm using vaginal access and uterine size as decision tree branches. We excluded the laparoscopic hysterectomy route. A prerobot cohort (2004-2005) was used to evaluate a practice change after the addition of robotic technology (2007)...
December 2, 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27926614/clinical-coordination-in-accountable-care-organizations-a-qualitative-study
#3
Valerie A Lewis, Karen Schoenherr, Taressa Fraze, Aleen Cunningham
BACKGROUND: Accountable care organizations (ACOs) are becoming a common payment and delivery model. Despite widespread interest, little empirical research has examined what efforts or strategies ACOs are using to change care and reduce costs. Knowledge of ACOs' clinical efforts can provide important context for understanding ACO performance, particularly to distinguish arenas where ACOs have and have not attempted care transformation. PURPOSE: The aim of the study was to understand ACOs' efforts to change clinical care during the first 18 months of ACO contracts...
December 6, 2016: Health Care Management Review
https://www.readbyqxmd.com/read/27926548/liver-transplantation-for-hepatocellular-carcinoma-current-update-on-treatment-and-allocation
#4
Leigh Anne Dageforde, Kathryn J Fowler, William C Chapman
PURPOSE OF REVIEW: This review discusses the current imaging modalities and criteria used to diagnose, and the role of liver transplantation as well as nonsurgical hepatic-directed therapies to treat hepatocellular carcinoma in the setting of chronic liver disease. RECENT FINDINGS: There has been continual evolution of guidelines, policies, and algorithms for the imaging diagnosis of hepatocellular carcinoma, particularly the Liver Imaging Reporting and Data System...
December 6, 2016: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/27926358/recent-advances-in-pancreatic-cancer-surgery-of-relevance-to-the-practicing-pathologist
#5
REVIEW
Lennart B van Rijssen, Steffi J E Rombouts, Marieke S Walma, Jantien A Vogel, Johanna A Tol, Isaac Q Molenaar, Casper H J van Eijck, Joanne Verheij, Marc J van de Vijver, Olivier R C Busch, Marc G H Besselink
Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10% to 20% of initially unresectable, to resectable disease...
December 2016: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/27926357/dissection-of-pancreatic-resection-specimens
#6
REVIEW
Caroline Sophie Verbeke, Ivar Prydz Gladhaug
Specimen grossing is a key step in the pathology examination of pancreatic resection specimens. Optimal display of pathologic changes and extensive tissue sampling are important determinants of the quality of pathology reporting. Divergence in macroscopic examination practice has led to considerable variation in the reporting of factors that are of clinical and prognostic significance. This article provides a detailed account of the macroscopic examination procedure with reference to current (inter-)national guidelines and recommendations...
December 2016: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/27925645/taking-time-to-feel-our-body-steady-increases-in-heartbeat-perception-accuracy-and-decreases-in-alexithymia-over-9-months-of-contemplative-mental-training
#7
Boris Bornemann, Tania Singer
The ability to accurately perceive signals from the body has been shown to be important for physical and psychological health as well as understanding one's emotions. Despite the importance of this skill, often indexed by heartbeat perception accuracy (HBPa), little is known about its malleability. Here, we investigated whether contemplative mental practice can increase HBPa. In the context of a 9-month mental training study, the ReSource Project, two matched cohorts (n = 77 and n = 79) underwent three training modules of 3 months' duration that targeted attentional and interoceptive abilities (Presence module), socio-affective (Affect module), and socio-cognitive (Perspective module) abilities...
December 7, 2016: Psychophysiology
https://www.readbyqxmd.com/read/27925606/increasing-awareness-and-acceptance-through-mindfulness-and-somatic-education-movements
#8
Paulo Vicente Bloise, Mário César Rezende Andrade, Hans Machado, Sérgio Baxter Andreoli
Context • The main feature of mindfulness-based interventions (MBI) is the encouragement of present moment awareness and of self-regulation, which are associated with health benefits. Meditating with the body in movement has been referred to as one of the most accessible ways of reaching such awareness. An MBI program, Mindfulness and Movements of Integration (MMI), has the same structure as mindfulness-based stress reduction (MBSR) but puts more emphasis on the body and uses somatic education (SE) movements instead of yoga postures...
October 2016: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/27925599/sparse-regularization-in-fuzzy-c-means-for-high-dimensional-data-clustering
#9
Xiangyu Chang, Qingnan Wang, Yuewen Liu, Yu Wang
In high-dimensional data clustering practices, the cluster structure is commonly assumed to be confined to a limited number of relevant features, rather than the entire feature set. However, for high-dimensional data, identifying the relevant features and discovering the cluster structure are still challenging problems. To solve these problems, this paper proposes a novel fuzzy c-means (FCM) model with sparse regularization (ℓq(0<q≤1)-norm regularization), by reformulating the FCM objective function into the weighted between-cluster sum of square form and imposing the sparse regularization on the weights...
December 1, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27925166/new-guidelines-for-screening-diagnosing-and-treating-gestational-diabetes-evaluation-of-maternal-and-neonatal-outcomes-in-finland-from-2006-to-2012
#10
Anni Ellenberg, Nanna Sarvilinna, Mika Gissler, Veli-Matti Ulander
INTRODUCTION: In this study, we have assessed the changes in pregnancy outcomes following the implementation of national guidelines for gestational diabetes mellitus (GDM). These national guidelines changed the screening policy from risk-based to comprehensive screening. MATERIAL AND METHODS: We designed a retrospective register-based cohort study based on the data from the Finnish Medical Birth Register and Hospital Discharge Register including 34 794 singleton births in 2006-2008 and 36 488 in 2010-2012...
December 7, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27925142/dg-connect-funded-projects-on-information-and-communication-technologies-ict-for-old-age-people-beyond-silos-carewell-and-smartcare
#11
W Keijser, E de Manuel-Keenoy, M d'Angelantonio, P Stafylas, P Hobson, G Apuzzo, M Hurtado, J Oates, J Bousquet, A Senn
Information and communication technologies (ICT) are promising for the long-term care of older and frequently frail people. These innovations can improve health outcomes, quality of life and efficiency of care processes, while supporting independent living. However, they may be disruptive innovations. As all European member states are facing an increasing complexity of health and social care, good practices in ICT should be identified and evaluated. Three projects funded by DG CNECT are related to Active and Healthy Ageing (AHA) and frailty: (i) BeyondSilos, dealing with independent living and integrated services, (ii) CareWell, providing integrated care coordination, patient empowerment and home support and (iii) SmartCare, proposing a common set of standard functional specifications for an ICT platform enabling the delivery of integrated care to older patients...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925097/assisted-therapy-with-dogs-in-pediatric-oncology-relatives-and-nurses-perceptions
#12
Rebeca Lima Moreira, Fabiane do Amaral Gubert, Leidiane Minervina Moraes de Sabino, Jéssica Lima Benevides, Marcela Ariadne Braga Gomes Tomé, Mariana Cavalcante Martins, Mychelangela de Assis Brito
Objective: to understand the perception of nursing staff professionals and legal guardians of children and adolescents with cancer regarding Assisted Therapy with dogs. Method: qualitative study based on participant observation conducted with 16 participants in a reference hospital of child cancer. We applied an in-depth interview and interpreted the data according to a content analysis technique. Results: the practice is admittedly beneficial to participants despite the fact they do not understand its true objectives and therapeutic applications...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27925090/storytelling-a-care-technology-in-continuing-education-for-active-ageing
#13
Nadia Pinheiro da Costa, Sandra Helena Isse Polaro, Eloá Aparecida Caliari Vahl, Lucia Hisako Takase Gonçalves
Objective: assessing relevance and effectiveness of care/educational technology in the form of "storytelling" as a strategy in the cultivation of active ageing (AA) for elderly users of a Basic Health Unit (BHU), from the Amazon region. Method: convergent care research (CCR) held in a BHU in Belém, state of Pará, with eight elderly ladies for testing this technology. An active ageing assessment questionnaire and WHOQOL-BREF - quality of life assessment were applied...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27925010/the-effects-of-a-simple-method-for-cryopreservation-and-thawing-procedures-on-cord-blood-derived-dc-based-esophageal-carcinoma-vaccine
#14
J Yu, L Xie, S Chen, J Zhang, G Guo, B Chen
BACKGROUND: Producing sufficient numbers of DCs at one time point and subsequently cryopreserving the generated DCs in ready-for-use aliquots for clinical application is useful in cancer treatment. OBJECTIVE: To study the effects of a simplified cryopreservation method and thawing procedures acting on the biological characteristics and specific cytotoxic activity of cord blood derived DC-based esophageal carcinoma vaccine. MATERIALS AND METHODS: CD34+ hematopoietic stem cells were isolated from cord blood using CD34+ Progenitor Cell Isolation Kit by magnetic cell sorting system (MACS)...
July 2016: Cryo Letters
https://www.readbyqxmd.com/read/27925004/appropriate-osmotic-balance-duration-for-different-volumes-of-ovarian-tissue-in-vitrification-solution-a-study-of-ovary-tissue-vitrification-and-transplantation-in-sheep
#15
L Dang, X Zheng, Q Chang, Y Yang, Y Wang, Y Cai, C Hei, H Wang, C Zhao, W Zhu, Y Wang
:   BACKGROUND: Auto-transplantation of cryopreserved ovarian tissue has become a promising method for fertility preservation and standardization of the process is crucial for practical applications. OBJECTIVE: Here we used different size of large sheep ovarian cortex to study the most suitable osmotic balance durations in the vitrification solution for large piece ovary cortex. MATERIALS AND METHODS: The ovarian cortices from six-month old female sheep were divided into 40 cubic mm, 80 cubic mm and 160 cubic mm volume, A two-step osmotic balance method was used based on the results from morphological and histological study, we detected the expression of VEGF after thawing, the percentage of follicles that survived and serum E2 levels,together with apoptosis test by TUNEL...
September 2016: Cryo Letters
https://www.readbyqxmd.com/read/27924997/characterization-of-normal-and-freeze-thawed-tissues-in-vitro-through-the-ultrasonic-integrated-backscatter
#16
L Sheng, P Yang, Z He, G Wang, J Luo, J Liu
BACKGROUND: The ultrasound guidance of cryotherapy could be improved if changes of tissue characterization parameters during freezing could be used to monitor freezing patterns and estimate the postoperative effects after surgery. OBJECTIVE: The ultrasonic integrated backscatter analysis holds promise as an effective method for signal analysis and characterization of thawed tissues. MATERIALS AND METHODS: The ultrasonic integrated backscatter has been found to be an important parameter for describing the ultrasonic scattering and characterization of biological tissues...
September 2016: Cryo Letters
https://www.readbyqxmd.com/read/27924754/relevance-of-randomised-controlled-trials-in-oncology
#17
REVIEW
Ian F Tannock, Eitan Amir, Christopher M Booth, Saroj Niraula, Alberto Ocana, Bostjan Seruga, Arnoud J Templeton, Francisco Vera-Badillo
Well-designed randomised controlled trials (RCTs) can prevent bias in the comparison of treatments and provide a sound basis for changes in clinical practice. However, the design and reporting of many RCTs can render their results of little relevance to clinical practice. In this Personal View, we discuss the limitations of RCT data and suggest some ways to improve the clinical relevance of RCTs in the everyday management of patients with cancer. RCTs should ask questions of clinical rather than commercial interest, avoid non-validated surrogate endpoints in registration trials, and have entry criteria that allow inclusion of all patients who are fit to receive treatment...
December 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27924552/what-is-behavioural-medicine-commentary-on-definition-proposed-by-dekker-stauder-and-penedo
#18
Marie Johnston, Derek Johnston
PURPOSE: Dekker et al. (2016) propose an updated definition of behavioural medicine. METHOD: In this commentary, we discuss how the field and the disciplines involved have changed over time before suggesting small amendments to the proposed definition. RESULTS: We suggest that the range of medicine which might be considered 'behavioural' is increasing to encompass virtually all medical practice. In addition, the role of behaviour and the potential for behaviour change as a means of improving health have become increasingly important...
December 6, 2016: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27924537/targeting-aflatoxin-biosynthetic-genes
#19
Ali Y Srour, Ahmad M Fakhoury, Robert L Brown
Chemical detoxification and physical destruction of aflatoxins in foods and feed commodities are mostly unattainable in a way that preserves the edibility of the food. Therefore, preventing mycotoxins in general and aflatoxins in particular from entering the food chain is a better approach. This requires early detection of the aflatoxin-causing organisms. Detection and quantification of aflatoxin-producing fungi has always been a challenge, especially within species of Aspergillus and Penicillium. Culture-based methods require a high level of expertise and a list of sophisticated equipment...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27924501/behavioral-intervention-reduces-unhealthy-eating-behaviors-in-preschool-children-via-a-behavior-card-approach
#20
Ming Lin, Li-Ping Pan, Juan Han, Li Li, Jing-Xiong Jiang, Run-Ming Jin
Many eating behaviors form in childhood, and some unhealthy behaviors may persist into adulthood and have potential impacts on people's health. This study evaluated the effectiveness of behavioral intervention in reducing consumption of Western fast food, sweetened beverages, fried food in preschool children, and changing parents' rewarding behaviors that encourage the consumption of the unhealthy foods. The research was a cluster randomized trial of seven kindergartens, involving 1138 children aged 3-6 years and their parents in Beijing, China...
December 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
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