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https://www.readbyqxmd.com/read/28331450/pulmonary-thromboendarterectomy-for-pulmonary-hypertension-before-considering-transplant
#1
Hannah Kooperkamp, Inder Mehta, David Fary, Michael Bates
BACKGROUND: In cases of chronic thromboembolic pulmonary hypertension (CTEPH), referral for possible surgical intervention is important because surgery can be curative. Surgery necessitates cardiopulmonary bypass and deep circulatory arrest with pulmonary thrombectomy and bilateral endarterectomy (PTE). If surgery fails, lung transplant is the next best surgical option. Medical treatment is also an important adjunct. CASE REPORT: A 35-year-old female presented 3 months after a pulmonary embolus was found to be completely occluding her left pulmonary artery...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28327448/prenatal-tobacco-exposure-birthweight-and-offspring-psychopathology
#2
Ardesheer Talati, Priya J Wickramaratne, Rikke Wesselhoeft, Myrna M Weissman
Although prenatal tobacco exposure (PTE) is associated with several adverse offspring mental health outcomes, mechanisms remain unclear. We test whether associations between PTE and offspring psychopathology are explained by birthweight, one of the earliest-occurring outcomes of PTE. The analysis focuses on 238 offspring from a family study of depression with (1) collected prenatal histories and (2) at least one clinical interview in adulthood to assess psychiatric problems. Exposure was categorized by maternal smoking of ≥10 cigarettes daily/nearly daily; diagnostic outcomes were confirmed by clinicians using the best-estimate procedure, blind to exposure...
March 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28316319/epileptic-spasms-in-paediatric-post-traumatic-epilepsy-at-a-tertiary-referral-centre
#3
Jun T Park, Harry T Chugani
To recognize epileptic spasms (ES) as a seizure type after traumatic brain injury (TBI), accidental or non-accidental, in infants and children. In the process, we aim to gain some insight into the mechanisms of epileptogenesis in ES. A retrospective electronic chart review was performed at the Children's Hospital of Michigan from 2002 to 2012. Electronic charts of 321 patients were reviewed for evidence of post-traumatic epilepsy. Various clinical variables were collected including age at TBI, mechanism of trauma, severity of brain injury, electroencephalography/neuroimaging data, and seizure semiology...
March 17, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28289496/surgical-treatment-of-chronic-thromboembolic-pulmonary-hypertension-pulmonary-thromboendarterectomy
#4
Michael M Madani
Pulmonary thromboendarterectomy (PTE), also referred to as pulmonary endarterectomy, is the definitive treatment for chronic thromboembolic pulmonary hypertension (CTEPH). The true incidence of CTEPH is unknown and difficult to ascertain; however, most experts agree that approximately 4% to 5% of all patients who have an acute episode of pulmonary embolism (PE) will continue to develop CTEPH. Based on an incidence rate of about 0.1% for acute PE, this translates into a CTEPH incidence of approximately 10,000 to 15,000 annually in the United States alone...
October 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28289495/treatment-of-chronic-thromboembolic-pulmonary-hypertension-the-role-of-medical-therapy-and-balloon-pulmonary-angioplasty
#5
Timothy M Fernandes, David S Poch, William R Auger
Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially curable disease when treated with pulmonary thromboendarterectomy (PTE). However, even at experienced surgical centers, nearly one-third of patients with CTEPH will be deemed inoperable for reasons including distal disease, comorbidities, or out-of-proportion pulmonary hypertension. It is in these patients with inoperable CTEPH that pulmonary hypertension (PH)-targeted medical therapy and balloon pulmonary angioplasty have potential therapeutic value...
October 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28286939/epidemiological-trend-of-pulmonary-thromboembolism-at-a-tertiary-hospital-in-korea
#6
Tae Yun Park, Jae-Woo Jung, Jae Chol Choi, Jong Wook Shin, Jae Yeol Kim, Byoung Whui Choi, In Won Park
Background/Aims: Despite increasing interest in pulmonary thromboembolism (PTE), data on recent trends in PTE incidence are limited. This study evaluated the recent incidence rate of PTE. Methods: We performed a retrospective chart review of patients with PTE admitted to Chung-Ang University Hospital during the 10-year period from 2006 to 2015. Age-standardized incidence and mortality rates were calculated by the direct method per 100,000 populations. To analyze the trend of risk factor, we also calculated the proportions of cancer, major operation, and recent major fracture over that time...
March 13, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28280942/perioperative-risk-factors-for-death-among-patients-with-symptomatic-pulmonary-thromboembolism
#7
REVIEW
(no author information available yet)
Perioperative pulmonary thromboembolism (PTE) is a fatal complication that may occur in patients who are undergoing surgery. This study aimed to identify risk factors for PTE-related death. This study evaluated data for the most recent 5-year period (2007-2011) from the Japanese Society of Anesthesiologists' database of patients who experienced perioperative PTE. We compared patients who died within 30 days of onset and patients who survived for > 30 days, and used logistic regression analysis to identify the independent risk factors...
March 9, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28269695/a-wirelessly-powered-homecage-with-animal-behavior-analysis-and-closed-loop-power-control
#8
Yaoyao Jia, Zheyuan Wang, Daniel Canales, Morgan Tinkler, Chia-Chun Hsu, Teresa E Madsen, S Abdollah Mirbozorgi, Donald Rainnie, Maysam Ghovanloo
This paper presents a new EnerCage-homecage system, EnerCage-HC2, for longitudinal electrophysiology data acquisition experiments on small freely moving animal subjects, such as rodents. EnerCage-HC2 is equipped with multi-coil wireless power transmission (WPT), closed-loop power control, bidirectional data communication via Bluetooth Low Energy (BLE), and Microsoft Kinect® based animal behavior tracking and analysis. The EnerCage-HC2 achieves a homogeneous power transfer efficiency (PTE) of 14% on average, with ~42 mW power delivered to the load (PDL) at a nominal height of 7 cm by the closed-loop power control mechanism...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269345/optimal-frequency-for-powering-millimeter-sized-biomedical-implants-inside-an-inductively-powered-homecage
#9
Hesam Sadeghi Gougheri, Mehdi Kiani
This paper presents the optimal design and operation frequency (f) of an inductively-powered homecage for powering biomedical devices with millimeter (mm) dimensions, implanted inside the body of freely-behaving small animal subjects, for longitudinal behavioral neuroscience and electrophysiology experiments. In order to improve the power transmission efficiency (PTE) for powering mm-sized implants, the geometry of the multi-coil inductive links in the form of 3- and 4-coil links as well as fp need to be co-optimized...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269344/inductive-power-transmission-to-millimeter-sized-biomedical-implants-using-printed-spiral-coils
#10
Ahmed Ibrahim, Mehdi Kiani
The operation frequency (f) has been a key parameter in optimizing wireless power transmission links for biomedical implants with millimeter (mm) dimensions. This paper studies the feasibility of using printed spiral coils (PSCs) for powering mm-sized implants with high power transmission efficiency (PTE) at different fps. Compared to wire-wound coils (WWCs), using a PSC in the implant side allows batch fabrication on rigid or flexible substrates, which can also be used as a platform for integrating implant components...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269276/toward-a-distributed-free-floating-wireless-implantable-neural-recording-system
#11
Pyungwoo Yeon, Xingyuan Tong, Byunghun Lee, Abdollah Mirbozorgi, Bruce Ash, Helmut Eckhardt, Maysam Ghovanloo
To understand the complex correlations between neural networks across different regions in the brain and their functions at high spatiotemporal resolution, a tool is needed for obtaining long-term single unit activity (SUA) across the entire brain area. The concept and preliminary design of a distributed free-floating wireless implantable neural recording (FF-WINeR) system are presented, which can enabling SUA acquisition by dispersedly implanting tens to hundreds of untethered 1 mm3 neural recording probes, floating with the brain and operating wirelessly across the cortical surface...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268706/optimal-resonance-configuration-for-ultrasonic-wireless-power-transmission-to-millimeter-sized-biomedical-implants
#12
Miao Meng, Mehdi Kiani
In order to achieve efficient wireless power transmission (WPT) to biomedical implants with millimeter (mm) dimensions, ultrasonic WPT links have recently been proposed. Operating both transmitter (Tx) and receiver (Rx) ultrasonic transducers at their resonance frequency (fr) is key in improving power transmission efficiency (PTE). In this paper, different resonance configurations for Tx and Rx transducers, including series and parallel resonance, have been studied to help the designers of ultrasonic WPT links to choose the optimal resonance configuration for Tx and Rx that maximizes PTE...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268112/taking-varenicline-for-smoking-cessation-a-rare-cause-of-pulmonary-thromboembolism-with-infarction
#13
Sun Hwa Lee, Seong Jong Yun, Seokyong Ryu, Seung Won Choi, Hye Jin Kim, Tae Kyug Kang, Sung Chan Oh, Suk Jin Cho
Varenicline (Champix®, Chantix®) is a partial agonist of the α4β2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the α7 nAChR. It has been used for smoking cessation since 2006. Varenicline has been associated with adverse cardiovascular (CV) events, including myocardial infarction, which may be caused by activation of the α7 nAChR receptor that in turn stimulates parasympathetic output from the brainstem to the heart, release of catecholamines, and has a prothrombotic effect. However, among the adverse CV events, the issue related to the varenicline-induced pulmonary thromboembolism (PTE) has not being addressed...
February 28, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28266746/high-efficiency-photovoltaic-devices-using-trap-controlled-quantum-dot-ink-prepared-via-phase-transfer-exchange
#14
Havid Aqoma, Muhibullah Al Mubarok, Wisnu Tantyo Hadmojo, Eun-Hye Lee, Tae-Wook Kim, Tae Kyu Ahn, Seung-Hwan Oh, Sung-Yeon Jang
Colloidal-quantum-dot (CQD) photovoltaic devices are promising candidates for low-cost power sources owing to their low-temperature solution processability and bandgap tunability. A power conversion efficiency (PCE) of >10% is achieved for these devices; however, there are several remaining obstacles to their commercialization, including their high energy loss due to surface trap states and the complexity of the multiple-step CQD-layer-deposition process. Herein, high-efficiency photovoltaic devices prepared with CQD-ink using a phase-transfer-exchange (PTE) method are reported...
March 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28264443/the-structure-activity-relationship-of-pterostilbene-against-candida-albicans-biofilms
#15
Dan-Dan Hu, Ri-Li Zhang, Yong Zou, Hua Zhong, En-Sheng Zhang, Xiang Luo, Yan Wang, Yuan-Ying Jiang
Candida albicans biofilms contribute to invasive infections and dramatic drug resistance, and anti-biofilm agents are urgently needed in the clinic. Pterostilbene (PTE) is a natural plant product with potentials to be developed as an anti-biofilm agent. In this study, we evaluated the structure-activity relationship (SAR) of PTE analogues against C. albicans biofilms. XTT (Sodium 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt) reduction assay was used to evaluate the activity of the analogues against C...
February 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28242457/prenatal-tobacco-exposure-maternal-postnatal-nicotine-dependence-and-adolescent-risk-for-nicotine-dependence-birth-cohort-study
#16
Natacha M De Genna, Lidush Goldschmidt, Nancy L Day, Marie D Cornelius
AIMS: The goals of this study are to determine if there is (a) a threshold effect for prenatal tobacco exposure (PTE) on adolescent risk for nicotine dependence, and (b) an additive effect of PTE and maternal postnatal nicotine dependence on adolescent risk for nicotine dependence. METHODS: Pregnant women were recruited in their 4th or 5th gestational month and asked about cigarette use during the first trimester. Mothers reported on third trimester cigarette use at delivery...
February 24, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28242442/genetic-biomarkers-of-posttraumatic-epilepsy-a-systematic-review
#17
REVIEW
Devyn Cotter, Andrew Kelso, Aidan Neligan
INTRODUCTION: Posttraumatic epilepsy (PTE) is caused by traumatic brain injury (TBI) and is an important contributor to the overall social and economic burden of epilepsy. Epidemiological studies suggest that there is a genetic contribution to the development of PTE. Identification of clinically useful genetic biomarkers is important for advancements in diagnosis and treatment of PTE. METHODS: A systematic review was performed on the existing literature of genetic biomarkers of posttraumatic epilepsy (PTE)...
February 9, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28240552/ikmtsl-pte-a-phospholipid-based-epr-probe-for-surface-electrostatic-potential-of-biological-interfaces-at-neutral-ph-effects-of-temperature-and-effective-dielectric-constant-of-the-solvent
#18
Maxim A Voinov, Christina T Scheid, Igor A Kirilyuk, Dmitrii G Trofimov, Alex I Smirnov
The synthesis and characterization of a lipidlike electrostatic spin probe, (S)-2,3-bis(palmitoyloxy)propyl 2-((4-(4-(dimethylamino)-2-ethyl-1-oxyl-5,5-dimethyl-2,5-dihydro-1H-imidazol-2-yl)benzyl)disulfanyl)ethyl phosphate (IKMTSL-PTE), are being reported. The intrinsic pKa(0) of IKMTSL-PTE was determined by X-band (9.5 GHz) electron paramagnetic resonance (EPR) titration of a water-soluble model compound, 4-(dimethylamino)-2-ethyl-2-(4-(((2-hydroxyethyl)disulfanyl)methyl)phenyl)-5,5-dimethyl-2,5-dihydro-1H-imidazol-1-oxyl (IKMTSL-ME), an adduct of methanethiosulfonate spin label IKMTSL and 2-mercaptoethanol...
March 10, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28235993/a-novel-two-step-sequential-bioaccessibility-test-for-potentially-toxic-elements-in-inhaled-particulate-matter-transported-into-the-gastrointestinal-tract-by-mucociliary-clearance
#19
Jawad Ali Hussein Alpofead, Christine M Davidson, David Littlejohn
A novel two-step sequential extraction has been developed to assess the bioaccessibility of As, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn in airborne particulate matter following inhalation and transport into the human gastrointestinal tract by mucociliary clearance. A new artificial mucus fluid (AMF) was used to determine the bioaccessible potentially toxic element (PTE) fraction in the upper airways, in sequence with the simplified bioaccessibility extraction test (SBET) or the stomach phase of the unified bioaccessibility method (gastric fluid only) (UBMG)...
February 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28227956/a-wirelessly-powered-homecage-with-animal-behavior-analysis-and-closed-loop-power-control
#20
Yaoyao Jia, Zheyuan Wang, Daniel Canales, Morgan Tinkler, Chia-Chun Hsu, Teresa E Madsen, S Abdollah Mirbozorgi, Donald Rainnie, Maysam Ghovanloo, Yaoyao Jia, Zheyuan Wang, Daniel Canales, Morgan Tinkler, Chia-Chun Hsu, Teresa E Madsen, S Abdollah Mirbozorgi, Donald Rainnie, Maysam Ghovanloo, Donald Rainnie, Chia-Chun Hsu, Teresa E Madsen, Morgan Tinkler, Daniel Canales, Zheyuan Wang, S Abdollah Mirbozorgi, Maysam Ghovanloo, Yaoyao Jia
This paper presents a new EnerCage-homecage system, EnerCage-HC2, for longitudinal electrophysiology data acquisition experiments on small freely moving animal subjects, such as rodents. EnerCage-HC2 is equipped with multi-coil wireless power transmission (WPT), closed-loop power control, bidirectional data communication via Bluetooth Low Energy (BLE), and Microsoft Kinect® based animal behavior tracking and analysis. The EnerCage-HC2 achieves a homogeneous power transfer efficiency (PTE) of 14% on average, with ~42 mW power delivered to the load (PDL) at a nominal height of 7 cm by the closed-loop power control mechanism...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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