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Seetharam Shiva Prasad, L Ramachandra, Vijay Kumar, Aniket Dave, Lalit K Mestha, Krithika Venkatarmani
BACKGROUND: Thermographic imaging is a non-invasive and radiation free imaging modality that measures the infrared radiation released by the body. Recently, there is a renewed interest regarding the scope of thermal imaging for breast cancer. OBJECTIVE: To evaluate the efficacy of thermographic breast imaging in detecting breast cancer. METHODS: A Prospective observational study was carried out from January 2014 to December 2014 at Kasturba Hospital, Manipal, India...
October 17, 2016: Breast Disease
Sudhir Adhikari, Kalipatnam Seshagiri Rao
BACKGROUND: Perinatal asphyxia with hypoxic ischemic encephalopathy (HIE) causes significant mortality and morbidity in developing countries. There is limited information about long term neurodevelopmental outcome of infants with neonatal encephalopathy. METHODS: Term infants with the diagnosis of perinatal asphyxia were followed up in neurodevelopmental clinics of Manipal Teaching hospital, Nepal. Study design was prospective mixed longitudinal study. Prematurity, major congenital malformations, other intracranial pathology, birth weight <2500g and chromosomal abnormalities were excluded...
September 30, 2016: Brain & Development
Ramesh Devkota, G M Khan, Kadir Alam, Amisha Regmi, Binaya Sapkota
BACKGROUND: Drugs used during pregnancy can adversely affect the health and life of the mother and unborn child. However, the fact that drugs are needed to mitigate complications during pregnancy cannot be avoided. The present study was designed to identify the common complications during pregnancy and assess the medications that have been used to mitigate those complications in an attempt to improve drug prescribing during pregnancy. METHODS: A hospital based cross sectional study was conducted at Manipal Teaching Hospital, Nepal in 275 pregnant women presenting with at least one complication and the drugs prescribed for the management of those complications were analyzed...
2016: BMC Pregnancy and Childbirth
Ranjan Shetty, Jayesh Prajapati, Umesh Pai, Kiran Shetty
Objective. The objective of the MANIPAL-FLEX study was to evaluate the feasibility, preliminary safety, and efficacy of the Supraflex sirolimus-eluting stent (SES) implantation, in de novo coronary artery disease, using clinical and quantitative coronary angiography (QCA) follow-ups. Methods. This was a prospective, nonrandomized, multicenter, single-arm study that enrolled 189 patients with de novo coronary artery disease who were treated with the Supraflex SES. Of 189 patients enrolled, the first 61 consecutive patients who consented to a 9-month follow-up evaluation by QCA, irrespective of presence of symptoms, were to be followed up with angiography at 9 months...
2016: Scientifica
Mukund P Srinivasan, Padmanabh K Kamath, Narayan M Bhat, Narasimha D Pai, Rajesh U Bhat, Poornima A Manjrekar, Chakrapani Mahabala
AIMS: To develop a risk score, for identifying severe and complex CAD in patients with type 2 diabetes mellitus. METHODS: In this cross sectional study, 179 patients with type 2 diabetes mellitus undergoing coronary angiogram for the evaluation of suspected coronary artery disease (CAD) were recruited at a tertiary-care hospital. Patients were divided into developmental (n=124) and validation (n=55) cohorts. Biochemical and anthropometric parameters were analysed...
August 22, 2016: Diabetes & Metabolic Syndrome
Nishu Singla, Shashidhar Acharya, Ramprasad Vasthare Prabhakar, Kalyana Chakravarthy, Deepak Singhal, Ritesh Singla
OBJECTIVES: (1) To assess the impact of different lifestyle factors on periodontal health of adults. (2) To assess the impact of overall/combined lifestyle variable (calculated by health practice index [HPI]) on periodontal health of adults. MATERIALS AND METHODS: A cross-sectional study consisting of a structured questionnaire on HPI, oral health-related behavior, and personal habits as well as sociodemographic variables was conducted on 800 subjects aged 20-50 years attending dental outreach set-ups of Manipal College of Dental Sciences, Manipal...
May 2016: Journal of Indian Society of Periodontology
Vanishri S Nayak, Abhilasha Priya, Nandini Bhat, Sunil S Nayak, Antony Sylvan D'Souza, Hemalatha Bangera, Suhani Sumalatha
INTRODUCTION: The dorsal interossei are the abductors of the fingers and the knowledge of its variation help the surgeon in treatment of fractures, claw hand and compartment syndromes. AIM: To note the origin, insertion, pattern of muscle fibres and tendon length of all the dorsal interossei of hand. MATERIALS AND METHODS: Routinely dissected 30 formalin fixed hand in the Department of Anatomy, KMC, Manipal, were observed for origin, insertion and tendon length and muscle pattern of dorsal interossei...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Sunayana Manipal, Sajjid Hussain, Umesh Wadgave, Prabu Duraiswamy, K Ravi
INTRODUCTION: Mouthwashes are often prescribed in dentistry for prevention and treatment of several oral conditions. In the recent times the use of naturally occurring products what is otherwise known as grandmothers remedy are used on a large scale. This has now called for a newer age of mouth washes but is the new age mouth washes at par with the gold standard or even better than them this study investigates. AIM: The aim of the present study was to compare the effect of two broad categories of mouth washes namely chlorhexidine and herbal mouth washes...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
Hui Qi, Binquan Wang, Wenyong Yu, Zhiying Zheng, Jie Yang
OBJECTIVE: Comparative analysis of the clinical curative effect of manipulative reduction and TRV- CRP treatment of BPPV, comfort degree during reset and quality of life improvement. METHOD: One hundred and thirty-two patients with BPPV were randomly divided into two groups ,one group underwent the traditional manip- ulative reduction, the other group with TRV-CRP. DRI and VAS was evaluated in the pre and after treatment and evaluation of the efficacy was conducted...
March 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Jeevan Acharya, Nils Kaehler, Sujan Babu Marahatta, Shiva Raj Mishra, Sudarshan Subedi, Bipin Adhikari
INTRODUCTION: Hospital based delivery has been an expensive experience for poor households because of hidden costs which are usually unaccounted in hospital costs. The main aim of this study was to estimate the hidden costs of hospital based delivery and determine the factors associated with the hidden costs. METHODS: A hospital based cross-sectional study was conducted among 384 post-partum mothers with their husbands/house heads during the discharge time in Manipal Teaching Hospital and Western Regional Hospital, Pokhara, Nepal...
2016: PloS One
Adam N McCaughan, Qingyuan Zhao, Karl K Berggren
We report on a method of nanoSQUID modulation which uses kinetic inductance rather than magnetic inductance to manip-ulate the internal fluxoid state. We produced modulation using injected current rather than an applied magnetic field. Using this injected current, we were able to observe the triangle-wave shaped modulation of the device critical current which was periodic according to the London fluxoid quantization condition. The measurement results also confirmed that the fluxoid state inside a superconducting loop can be manipulated using primarily kinetic inductance...
2016: Scientific Reports
Shweta Yellapurkar, Srikant Natarajan, Karen Boaz, Mohan Baliga, Premalatha Shetty, Nidhi Manaktala, Mukul Prasad, Mahalakshmi Ravi
INTRODUCTION: The infiltration of tumour stroma by eosinophils, Tumour-Associated Tissue Eosinophilia (TATE) is known to modulate the evolution of Oral Squamous Cell Carcinoma (OSCC). Identification of eosinophils in the inflammatory stroma has been proven to be an important factor in prognostication of malignant tumours including cancers of mouth, oesophagus, larynx, pharynx, breast, lung, intestine and genitourinary tract. AIM: Our study aimed to assess the role of TATE as a prognosticator in OSCC as visualized by Haematoxylin and Eosin (H&E) and congo red staining...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
M Sonal Sekhar, Roy Raymol Thomas, M K Unnikrishnan, K Vijayanarayana, Gabriel Sunil Rodrigues
Studies have reported that health-related quality of life (HRQoL) is adversely affected by diabetic foot ulcer (DFU). There is a paucity of data on the effects of foot ulcers on HRQoL of diabetes patients in our population. Because South-Asians, especially Indians, have unique features related to diabetes and its complications, generalizing the data about their effect on HRQoL from any other part of the world is not a pragmatic approach. This study evaluated the impact of foot ulcers on HRQoL of diabetes patients...
September 2015: Seminars in Vascular Surgery
Jeevan Acharya
OBJECTIVES: The Government of Nepal revised free maternity health services, "Aama Surakshya Karyakram", beginning at the start of Fiscal Year 2012/13, which specifies the services to be funded, the tariffs for reimbursement, and the system for claiming and reporting on free deliveries each month. This study was designed to investigate the amount of monetary expenditure incurred by families using apparently free maternity services. METHODS: Between August 2014 and December 2014, a hospital-based cross-sectional study was conducted at Manipal Teaching Hospital and Western Regional Hospital...
February 2016: Osong Public Health and Research Perspectives
Mayuri Banerjee, Ramachandra Kamath, Rajnarayan R Tiwari, Narayana Pillai Sreekumaran Nair
BACKGROUND: India being a developing country has tremendous demand of physical infrastructure and construction work as a result there is a raising demand of construction workers. Workers in construction industry are mainly migratory and employed on contract or subcontract basis. These workers face temporary relationship between employer and employee, uncertainty in working hours, contracting and subcontracting system, lack of basic continuous employment, lack basic amenities, and inadequacy in welfare schemes...
September 2015: Indian Journal of Occupational and Environmental Medicine
Hosuru Subramanya Supram, Shishir Gokhale, Brijesh Sathian, Dharma Raj Bhatta
BACKGROUND: The HIV, HBV and HCV viruses are the major public health concern all over the world including Nepal. The aim of the study is to determine the rate of HBV and HCV co-infections in patients with HIV infection. METHODS: The study cohort included 218 consecutive HIV infected patients who were examined for co-infection with HBV or HCV or both at Manipal teaching hospital, Western Nepal. The demographic data of the subjects was collected retrospectively. The data was analyzed with SPSS software and EPI Info to measure the correlation of variables and infection rates...
June 2015: Nepal journal of epidemiology
Darshan Bhagwan, Ashwini Kumar, Chythra Raghavendra Rao, Asha Kamath
INTRODUCTION: Postpartum is the most neglected period in reproductive cycle of woman. Prevalence of anaemia in developing countries ranges from 50-95%. AIM: To estimate the prevalence of anaemia among postnatal mothers. SETTING AND DESIGN: A community based cross-sectional study among recently delivered mothers residing in field practice area of Department of Community Medicine, Kasturba Medical College, Manipal, India. MATERIALS AND METHODS: The study sample included 401 respondents who were selected using stratified random sampling with proportionate allocation from all rural health centres...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
Supram Hosuru Subramanya, Sangita Thapa, Sanjiv Kumar Dwedi, Shishir Gokhale, Brijesh Sathian, Niranjan Nayak, Indira Bairy
BACKGROUND: Streptococcus pneumoniae and Haemophilus influenzae are important human pathogens. The risk of airborne and droplet-transmitted respiratory tract infections in healthcare workers (HCW) is substantial. The aim of this study was to determine the extent of oropharyngeal colonization with S. pneumoniae and Haemophilus spp. their antibiogram and risk factors of colonization in HCW at a tertiary care center, Western Nepal. METHODS: During 3 month period, 100 oropharyngeal swab specimens were collected from HCW of Manipal Teaching Hospital and 50 from non HCW from community...
2016: BMC Research Notes
Ramnarayan Komattil, Shyamala Handattu Hande, Ciraj Ali Mohammed, Barathi Subramaniam
The study aimed at evaluating the personal and professional development (PPD) module in the undergraduate medical curriculum in Melaka Manipal Medical College, India. PPD hours were incorporated in the curriculum. A team of faculty members and a faculty coordinator identified relevant topics and students were introduced to topics such as medical humanities, leadership skills, communication skills, ethics, professional behavior, and patient narratives. The module was evaluated using a prevalidated course feedback questionnaire which was administered to three consecutive batches of students from March 2011 to March 2013...
March 2016: Korean Journal of Medical Education
Sudesh Gyawali, P Ravi Shankar, Phanindra Prasad Poudel, Archana Saha
INTRODUCTION: Studies have shown self-medication to be common among medical students. These studies are however, few in Nepal. The present study assessed knowledge, attitude, and practice of self-medication among second and fourth semesters' undergraduate medical students and studied differences in knowledge and attitude (if any) among different subgroups of the respondents. MATERIALS AND METHODS: A cross-sectional survey was conducted using a questionnaire among basic science medical students of Manipal College of Medical Sciences, Nepal...
December 2015: Journal of Clinical and Diagnostic Research: JCDR
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