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Dilasma Ghartimagar, Arnab Ghosh, Sushil Ram Shrestha, Sachet Shrestha, Sushma Thapa, Raghavan Narasimhan, O P Talwar
INTRODUCTION: Basal cell carcinoma is the most common form of cancer in humans and comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rapidly increasing. The objective of the study is to identify the epidemiology, its topography and different histological subtypes of basal cell carcinoma in patients with or without Xeroderma Pigmentosum. METHODS: A cross-sectional descriptive study was conducted at Manipal Teaching Hospital, Pokhara from Jan 2009 to Dec 2016...
October 2017: JNMA; Journal of the Nepal Medical Association
Sonam Chaudhary, Sajana Deuja, Munna Alam, Poonam Karmacharya, Monami Mondal
INTRODUCTION: Blood grouping is conventionally done with invasive method by taking blood samples. The objective of this study is to determine blood group with uninvasive procedure by taking fingerprints of the participants and know the associations between their fingerprints and blood groups. METHODS: Seven hundred participants of both genders with no any age limitation from Manipal Teaching Hospital and Manipal College of Medical Sciences were randomly selected...
October 2017: JNMA; Journal of the Nepal Medical Association
Animesh Hazari, Arun G Maiya, Shivashankara K N
BACKGROUND: A kinetic change in thefoot like altered plantar pressure is the most common etiological risk factor for causing foot ulcers among people with diabetes mellitus. Kinematic alterations in joint angle and spatiotemporal parameters of the gait have also been frequently observed in participants with diabetes peripheral neuropathy. Diabetes peripheral neuropathy is the most common long-term standing complication of type 2 diabetes mellitus. It leads to various micro and macrovascular related complication of the foot...
February 1, 2018: Journal of the American Podiatric Medical Association
Sreekumaran Nair, Leslie Edward Lewis, Myron Anthony Godinho, Shruti Murthy, Theophilus Lakiang, Bhumika T Venkatesh
INTRODUCTION: India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. METHODS AND ANALYSIS: This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India...
January 10, 2018: BMJ Open
S P Somashekhar, M-J Sepúlveda, S Puglielli, A D Norden, E H Shortliffe, C Rohit Kumar, A Rauthan, N Arun Kumar, P Patil, K Rhee, Y Ramya
Background: Breast cancer oncologists are challenged to personalize care with rapidly changing scientific evidence, drug approvals, and treatment guidelines. Artificial intelligence (AI) clinical decision-support systems (CDSSs) have the potential to help address this challenge. We report here the results of examining the level of agreement (concordance) between treatment recommendations made by the AI CDSS Watson for Oncology (WFO) and a multidisciplinary tumor board for breast cancer...
January 9, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Chaya Ranasinghe, Pallavi G Shettigar, Meenakshi Garg
Context: Nutrition plays a vital role in the quality of life in postmenopausal women. Aim: The aim is to determine the dietary intake, physical activity, and assess the body mass index (BMI) among postmenopausal women. Settings and Design: A community-based sample survey. Materials and Methods: The present study included 140 postmenopausal women (40-70 years) from Udupi, Manipal areas of Karnataka. The study was carried out between July and December 2013...
October 2017: Journal of Mid-life Health
Pramod Kumar Yadav, Brijesh Sathian, Rishi Sherchan, Huda Fatima, Krishna Sharan, Syed Ather Hussain, Rachit Chawla, Ahmed Alsayyah, Alankrita Taneja
Childhood cancers form a rare and heterogeneous group which fortunately have a higher cure rate than adult cancers. A few non-profit organizations in Nepal have extended support to help patients suffering from cancer, but their main focus has been on adults. The objective of this study was to establish the pattern of childhood cancers in the Western region of Nepal. We reviewed cases receiving external radiotherapy with both palliative and curative intent between 28th September 2010 and 30th September 2015 at the Department of Radiotherapy and Oncology, Manipal Teaching Hospital affiliated with Manipal College of Medical Sciences, Pokhara, Nepal...
December 28, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
Stefan F Weber, Kavitha Saravu, Tom Heller, Rajagopal Kadavigere, Shashidhar Vishwanath, Stephan Gehring, Sabine Bélard, And Pocus Eti Study Group
Diagnosing extrapulmonary tuberculosis (EPTB) is challenging. Point-of-care ultrasound (POCUS) for human immunodeficiency virus (HIV)-associated EPTB is applied in sub-Saharan Africa. This study aimed at evaluating the applicability of POCUS for diagnosing EPTB in HIV-positive and HIV-negative presumptive tuberculosis (TB) patients in India, a country of moderate relative TB and HIV burden. Presumptive TB patients at Kasturba Hospital, Manipal, India, prospectively underwent POCUS evaluating for pericardial, pleural and ascitic effusion, abdominal lymphadenopathy, and hepatic and splenic microabscesses...
October 16, 2017: American Journal of Tropical Medicine and Hygiene
Suhaj Abdulsalim, Mazhuvancherry Kesavan Unnikrishnan, Mohan K Manu, Alian A Alrasheedy, Brian Godman, Donald E Morisky
BACKGROUND: COPD is characterised by a progressive airflow limitation in the lungs. However, adherence to therapy improves management of symptoms and delays disease progression. Therefore, patients' knowledge and awareness about the disease are important. Hence, pharmacist-led educational interventions could achieve this and improve medication adherence. OBJECTIVE: This study evaluated the effectiveness of a clinical pharmacist-led intervention on medication adherence in COPD patients in a teaching hospital...
October 26, 2017: Research in Social & Administrative Pharmacy: RSAP
Anjali Sivaramakrishnan, John M Solomon, Natarajan Manikandan
OBJECTIVE: Spasticity following spinal cord injury (SCI) can impair function and affect quality of life. This study compared the effects of transcutaneous electrical nerve stimulation (TENS) and functional electrical stimulation (FES) on lower limb spasticity in patients with SCI. DESIGN: Double blind randomized crossover design. SETTING: Neuro-rehabilitation unit, Manipal University, India. PARTICIPANTS: Ten participants (age: 39 ± 13...
October 25, 2017: Journal of Spinal Cord Medicine
Nagesh Kamat, Ganesh Pai, Surulivel Rajan Mallayasamy, Asha Kamath, Rajasulochana S
BACKGROUND: Chronic pancreatitis (CP) is a leading cause of hospitalization among gastrointestinal diseases resulting in considerable financial burden to patients. However the direct costs for nonsurgical management in CP remains unexplored. METHODS: A cross sectional study was carried out (2011-14) in the Department of Gastroenterology, Kasturba Hospital, Manipal, India. Demographic and clinical data on laboratory investigations, interventions and follow up were obtained from the medical records department...
October 12, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
Sudhir Adhikari, Kalipatanam Seshagiri Rao, Ganesh B K, Namraj Bahadur
BACKGROUND: Neonatal mortality rate of developing countries is declining over decades. In the recent years increasing number of preterm and high risk neonates have facilities for tertiary care treatment. The aim of the study was to assess the morbidities and outcome of neonatal intensive care admissions. METHODS: It was a retrospective observational study carried out in neonatal intensive care unit of the Manipal Teaching Hospital, Pokhara, Nepal from January 2014 to December 2015...
September 8, 2017: Journal of Nepal Health Research Council
J Deloumeaux, B Bhakkan, R Eyraud, F Braud, N Manip M'Ebobisse, P Blanchet, L Brureau
PURPOSE: The Caribbean population of Guadeloupe has one of the highest incidence rates of prostate cancer worldwide. In 2008, a population-based cancer registry was set up for the monitoring of cancer incidence in the aftermath of the environmental pollution with chlordecone, a persistent organochlorine insecticide formerly used in banana plantations. We describe the clinical presentation, incidence, mortality and survival of prostate cancer for the period 2008-2013. METHODS: The Guadeloupe cancer registry has been routinely collecting all incident cases of cancer since 2008...
November 2017: Cancer Causes & Control: CCC
Shetty Pooja, Sasidharanpillai Sabeena, Bhaskar Revti, Ramachandran Sanjay, Aithal Anjali, Kumar Rajendra, Sushama Aswathyraj, Dsouza Giselle, Maity Hindol, Govindakarnavar Arunkumar
Dengue is found to be the most prevalent arboviral disease affecting humans. Tropical and subtropical regions are at high risk of dengue virus infections. The clinical manifestations often range from mild fever to fever with hemorrhagic manifestations and shock. Since 2010, India is witnessing a marked increase in the number of Dengue Virus Serotype 1(DENV-1) apart from Dengue Virus 2 (DENV-2) and Dengue Virus 3 (DENV-3) Serotypes. The present study was undertaken to understand the circulating genotypes of DENV-1 in South West India by sequencing the envelope gene of DENV-1 samples representative of the time period 2014-2015...
September 11, 2017: Japanese Journal of Infectious Diseases
Girish Menon, Rajesh Nair, I K Laskhman, Vinod Kumar, G Lakshmi Prasad
Kasturba Medical College (KMC), Manipal, is the oldest and one of the most reputed medical institutes in coastal Karnataka, catering to a population of over 4 million, spanning a stretch of over 350 kms along the southwest coast of India from Mangalore to Goa. The Department of Neurosurgery at KMC, established in 1968, continues to be the leading and most preferred referral center providing high quality neurosurgical services in this region. The article provides an insight into the origin of the department, its infancy and teething troubles, its continuous growth and landmark achievements over the years...
September 2017: Neurology India
Tripti Pande, Kavitha Saravu, Zelalem Temesgen, Al Seyoum, Shipra Rai, Raghavendra Rao, Deekshith Mahadev, Madhukar Pai, Marie-Pierre Gagnon
BACKGROUND: Tuberculosis (TB) is the leading infectious killer, and India accounts for 2.8 of the 10.4 million TB cases that occur each year, making it the highest TB burden country worldwide. Poor quality of TB care is a major driver of the epidemic in India. India's large private, unregulated sector manages over 50% of the TB patients, with studies showing suboptimal diagnosis and treatment in the private sector. Better education of doctors using mobile applications (apps) is a possible solution...
2017: MHealth
Vijendra Pal Singh, Izni Syazana Osman, Nur Amanina Rahmat, Nur Ashikin Abu Bakar, Nurul Fathin Natasha Abdul Razak, Sowmya Nettem
BACKGROUND: Cross contamination of HIV is a real threat today. Dental treatment often includes direct contact with a patient's blood and saliva, therefore dental professionals can be easily exposed to HIV microorganisms. Hence, it is essential to gain insight into dental students' knowledge and attitude towards HIV patients. METHOD: A cross-sectional survey of 186 clinical year dental students (year 3, 4 and 5) in the 2015-2016 academic session at the Faculty of Dentistry, Melaka-Manipal Medical College (MMMC), Manipal University, Melaka volunteered to participate in the study...
May 2017: Malaysian Journal of Medical Sciences: MJMS
Seetharam Prasad, Padmapriya Jaiprakash, Aniket Dave, Deepti Pai
OBJECTIVE: To study idiopathic granulomatous mastitis with respect to its various clinical features, etiologic factors, treatment modalities and complications. MATERIAL AND METHODS: Retrospective study of all patients who were diagnosed with idiopathic granulomatous mastitis from 1(st) January 2006 to 31(st) December 2014 at Kasturba Hospital, Manipal, India (a tertiary care referral centre). The research was performed according to the World Medical Association Declaration of Helsinki...
2017: Turkish Journal of Surgery
L S Ashwini, S Nagabhooshana Somayaji, Mohandas Rao, Sapna Marpalli
Division of nerves close to their origin and muscular entrapments by nerves in the limbs is not very common. Femoral nerve is the largest branch of the lumbar plexus and arises from dorsal divisions of ventral rami of L2 to L4 spinal nerves. During routine cadaveric dissection for first year medical students at Melaka Manipal Medical College (Manipal Campus), Karnataka, India, we observed a variation in the division and course of left femoral nerve in about 65-year-old male cadaver. The femoral nerve was split into two divisions above the inguinal ligament after its origin from the lumbar plexus...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
Karvannan Harikesavan, Raj D Chakravarty, Arun G Maiya, Sanjay P Hegde, Shivakumar Y Shivanna
BACKGROUND: Total knee replacement (TKR) is the commonest surgical procedure for patients with severe pain and impaired physical function following end stage knee osteoarthritis. The hip abductors are well renowned in stabilization of the trunk and hip during walking, maintaining the lower limb position, and transferring the forces from the lower limbs to the pelvis. OBJECTIVE: To assess the efficacy of hip abductor strengthening exercise on functional outcome using performance based outcome measures following total knee replacement...
2017: Open Rheumatology Journal
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