keyword
MENU ▼
Read by QxMD icon Read
search

Pediatric pulmonary

keyword
https://www.readbyqxmd.com/read/29923941/intensive-care-mortality-prognostic-model-for-pediatric-pulmonary-hypertension
#1
Emily Morell Balkin, Matt S Zinter, Satish K Rajagopal, Roberta L Keller, Jeffrey R Fineman, Martina A Steurer
OBJECTIVES: The disease burden and mortality of children with pulmonary hypertension are significantly higher than for the general PICU population. We aimed to develop a risk-adjustment tool predicting PICU mortality for pediatric pulmonary hypertension patients: the Pediatric Index of Pulmonary Hypertension Intensive Care Mortality score. DESIGN: Retrospective analysis of prospectively collected multicenter pediatric critical care data. SETTING: One-hundred forty-three centers submitting data to Virtual Pediatric Systems database between January 1, 2009, and December 31, 2015...
June 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29923937/pulmonary-functions-in-children-ventilated-for-acute-hypoxemic-respiratory-failure
#2
Stanzen Chakdour, Pankaj C Vaidya, Suresh Kumar Angurana, Jayashree Muralidharan, Meenu Singh, Sunit C Singhi
OBJECTIVE: To assess pulmonary functions of children who received mechanical ventilation for acute hypoxemic respiratory failure. DESIGN: Longitudinal study. SETTING: PICU and Pediatric Pulmonology Clinic of a tertiary care teaching hospital in North India. PATIENTS: All children, 5-12 years old, ventilated for acute hypoxemic respiratory failure in PICU from July 2012 to June 2013 and survived. INTERVENTIONS: The baseline admission variables recorded were as follows: age, sex, duration of illness, primary diagnosis at admission, Pediatric Risk of Mortality III score, lung injury score, mechanical ventilation parameters, oxygenation indices, and duration of PICU stay...
June 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29920993/quantitative-systems-pharmacology-modeling-of-acid-sphingomyelinase-deficiency-and-the-enzyme-replacement-therapy-olipudase-alfa-is-an-innovative-tool-for-linking-pathophysiology-and-pharmacology
#3
Chanchala D Kaddi, Bradley Niesner, Rena Baek, Paul Jasper, John Pappas, John Tolsma, Jing Li, Zachary van Rijn, Mengdi Tao, Catherine Ortemann-Renon, Rachael Easton, Sharon Tan, Ana Cristina Puga, Edward H Schuchman, Jeffrey S Barrett, Karim Azer
Acid sphingomyelinase deficiency (ASMD) is a rare lysosomal storage disorder with heterogeneous clinical manifestations, including hepatosplenomegaly and infiltrative pulmonary disease, and is associated with significant morbidity and mortality. Olipudase alfa (recombinant human acid sphingomyelinase) is an enzyme replacement therapy under development for the non-neurological manifestations of ASMD. We present a quantitative systems pharmacology (QSP) model supporting the clinical development of olipudase alfa...
June 19, 2018: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/29915781/editorial-neonatal-and-pediatric-cerebro-cardio-pulmonary-resuscitation-ccpr-where-do-we-stand-and-where-are-we-heading
#4
EDITORIAL
Utpal Bhalala, Graeme Polglase, Eugene Dempsey
No abstract text is available yet for this article.
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29912937/comparison-of-three-non-invasive-hemodynamic-monitoring-methods-in-critically-ill-children
#5
Chanapai Chaiyakulsil, Marut Chantra, Poomiporn Katanyuwong, Anant Khositseth, Nattachai Anantasit
INTRODUCTION: Hemodynamic parameters measurements were widely conducted using pulmonary artery catheter (PAC) with thermodilution as a reference standard. Due to its technical difficulties in children, transthoracic echocardiography (TTE) has been widely employed instead. Nonetheless, TTE requires expertise and is time-consuming. Noninvasive cardiac output monitoring such as ultrasonic cardiac output monitor (USCOM) and electrical velocimetry (EV) can be performed rapidly with less expertise requirement...
2018: PloS One
https://www.readbyqxmd.com/read/29912067/rbc-exposure-in-pediatric-extracorporeal-membrane-oxygenation-epidemiology-and-factors-associated-with-large-blood-transfusion-volume
#6
Conor P O'Halloran, Peta M A Alexander, Kristofer G Andren, Jessica Mecklosky, Joshua W Salvin, Stephanie Larsen, Jill Zalieckas, Francis Fynn-Thompson, Ravi R Thiagarajan
OBJECTIVES: To quantify and identify factors associated with large RBC exposure in children supported with extracorporeal membrane oxygenation. DESIGN: Retrospective cohort study. SETTING: Single tertiary care children's hospital. PATIENTS: One-hundred twenty-two children supported with extracorporeal membrane oxygenation for greater than 12 hours during January 1, 2015, to December 31, 2016. INTERVENTIONS: None...
June 14, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29911888/epidemiology-of-clonal-pseudomonas-aeruginosa-infection-in-a-canadian-cystic-fibrosis-population
#7
Maggie A Middleton, Mehdi Layeghifard, Michelle Klingel, Sanja Stanojevic, Yvonne C W Yau, James E A Zlosnik, Adele Coriati, Felix A Ratjen, Elizabeth D Tullis, Anne Stephenson, Pearce Wilcox, Andreas Freitag, Mark Chilvers, Martha McKinney, Annick Lavoie, Pauline W Wang, David S Guttman, Valerie J Waters
RATIONALE: The extent of the genetic relatedness among Pseudomonas aeruginosa isolates and its impact on clinical outcomes in the cystic fibrosis (CF) population is poorly understood. OBJECTIVES: The objectives of this study were to determine the prevalence of clonal P. aeruginosa infection in Canada and to associate P. aeruginosa genotypes with clinical outcomes. METHODS: This was an observational study of adult and pediatric CF patients across Canada...
June 18, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29907635/increasing-rate-of-pulmonary-embolism-diagnosed-in-hospitalized-children-in-the-united-states-from-2001-to-2014
#8
Shannon L Carpenter, Troy Richardson, Matt Hall
Although rare in children, pulmonary embolism (PE) can cause significant morbidity and mortality. Overall rates of venous thromboembolism (VTE) are increasing in hospitalized children. By using the Pediatric Health Information System database, we evaluated incidence, treatment, and outcome of PE in children younger than age 18 years from 2001 to 2014. Demographic characteristics for those admitted with VTE alone and those admitted with PE were compared. Rates of PE by year were compared with the number of hospital and VTE admissions...
June 26, 2018: Blood Advances
https://www.readbyqxmd.com/read/29907161/correction-to-correlation-analysis-on-serum-inflammatory-cytokine-level-and-neurogenic-pulmonary-edema-for-children-with-severe-hand-foot-mouth-disease
#9
Jin-Fang Sun, Hao-Lan Li, Bao-Xia Sun
The original publication of this article [1] contained two erroneous paragraphs related to the time and place for the admission of the pediatric patients with clinically diagnosed severe HFMD. The updated information has been indicated in bold.
June 15, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29905401/monitoring-pulmonary-health-in-swiss-childhood-cancer-survivors
#10
Rahel Kasteler, Linda M H Kam, Annette Weiss, Nicolas Waespe, Grit Sommer, Florian Singer, Nicolas X von der Weid, Marc Ansari, Claudia E Kuehni
BACKGROUND: Childhood cancer survivors are at increased risk for pulmonary morbidity and mortality. International guidelines recommend pulmonary function tests (PFT) during follow-up care. This nationwide study assessed how many children received PFT within 5 years after pulmotoxic treatment in Switzerland, types of tests, and predictors for testing. METHODS: We included all children from the Swiss Childhood Cancer Registry who were diagnosed with cancer from 1990 to 2013 at age 0-16 years, survived for ≥2 years from diagnosis, and had pulmotoxic chemotherapy with bleomycin, busulfan, nitrosoureas, and/or chest radiotherapy...
June 15, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29899776/endovascular-retrieval-of-detached-ventriculoatrial-shunt-into-pulmonary-artery-in-pediatric-patient-case-report
#11
Mohammed Aloddadi, Safar Alshahrani, Ibrahim Alnaami
The management of hydrocephalus represents a neurosurgical challenge. Ventriculoperitoneal (VP) shunts are usually the treatment of choice for hydrocephalus. However, when VP shunt is not an option, ventriculoatrial (VA) shunt becomes a second choice. VA shunts have special complications such as postoperative neck hematomas, shunt nephritis, and migration of the distal segment. There are two main techniques for the retrieval of migrated VA shunt: either by retrieval of the broken segment by thoracotomy, which is highly invasive, or by transvenous approach...
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29896859/right-ventricular-base-apex-ratio-in-the-assessment-of-pediatric-pulmonary-arterial-hypertension-results-from-the-european-pediatric-pulmonary-vascular-disease-network
#12
Martin Koestenberger, Alexander Avian, Andreas Gamillscheg, Hannes Sallmon, Gernot Grangl, Ante Burmas, Sabrina Schweintzger, Stefan Kurath-Koller, Gerhard Cvirn, Georg Hansmann
BACKGROUND: Echocardiographic determination of the RV end-systolic base/apex (RVESb/a) ratio was proposed to be of clinical value for the assessment of pulmonary arterial hypertension (PAH) in adults. HYPOTHESIS: We hypothesized that the RVES b/a ratio will be affected in children with PAH and aimed to correlate the RVES b/a ratio with conventionally used echocardiographic and hemodynamic variables, and with NYHA functional class (FC). METHODS: We first determined normal pediatric values for the RVES b/a ratio in 157 healthy children (68 male; age range: 0...
June 12, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29893951/course-of-illness-after-viral-infection-in-indian-children-with-cystic-fibrosis
#13
Krishna Mohan Gulla, Arvind Balaji, Aparna Mukherjee, Kana Ram Jat, Jhuma Sankar, Rakesh Lodha, Sushil K Kabra
Objective: To study the clinical impact of respiratory viral infection in children with cystic fibrosis (CF). Design: Retrospective cohort study. Setting: Tertiary care referral centre for CF in India. Participants/patients: Children with CF attending a pediatric chest clinic. Methods: Case records of the children with CF who had a pulmonary exacerbation with documented acute respiratory viral infection between October 2013 and December 2014 (Group I) and an equal number of controls (Group II) with pulmonary exacerbation in absence of acute respiratory viral infection were reviewed...
June 9, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29892036/association-of-newborn-screening-metabolites-with-risk-of-wheezing-in-childhood
#14
Brittney M Donovan, Kelli K Ryckman, Patrick J Breheny, Tebeb Gebretsadik, Kedir N Turi, Emma K Larkin, Yinmei Li, Mary C Dorley, Tina V Hartert
BACKGROUND: There are critical gaps in our understanding of the temporal relationships between metabolites and subsequent asthma development. This is the first study to examine metabolites from newborn screening in the etiology of early childhood wheezing. METHODS: One thousand nine hundred and fifty one infants enrolled between 2012 and 2014 from pediatric practices located in Middle Tennessee in the population-based birth cohort study, the Infant Susceptibility to Pulmonary Infections and Asthma Following RSV Exposure Study (INSPIRE), were linked with metabolite data from the Tennessee Newborn Screening Program...
June 1, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29891258/epidemiology-of-lower-extremity-deep-venous-thrombosis-in-critically-ill-adolescents
#15
Edward Vincent S Faustino, Veronika Shabanova, Matthew G Pinto, Simon Li, Erin Trakas, Michael Miksa, Shira Gertz, Lee A Polikoff, Massimo Napolitano, Adele R Brudnicki, Joana A Tala, Cicero T Silva
OBJECTIVE: To determine the epidemiology of lower extremity deep venous thrombosis (DVT) in critically ill adolescents, which currently is unclear. STUDY DESIGN: We performed a multicenter, prospective, cohort study. Adolescents aged 13-17 years who were admitted to 6 pediatric intensive care units and were anticipated to receive cardiopulmonary support for at least 48 hours were eligible, unless they were admitted with DVT or pulmonary embolism or were receiving or anticipated to receive therapeutic anticoagulation...
June 8, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29886608/-prenatal-interventional-therapy-in-two-cases-with-critical-pulmonary-stenosis-or-pulmonary-atresia-with-intact-ventricular-septum
#16
C C Pang, W Pan, Z W Zhang, C B Zhou, Y F Li, X Zhang, F Z Han, Y X Sun, S Wang, J Zhuang
Objectives: Two cases who underwent fetal pulmonary valvuloplasty (FPV) for pulmonary atresia with intact ventricular septum (PA-IVS) or critical pulmonary stenosis with intact ventricular septum (CPS-IVS) successfully were reported. The aim of the report was to explore the criteria for case selection, the technical essentials of FPV, and the postpartum outcome of the fetus. Methods: One case with PA-IVS and the other with CPS-IVS were enrolled in September 2016 and February 2017 in Guangdong General Hospital, and both cases were diagnosed with severe right ventricular dysplasia and tricuspid regurgitation by fetal echocardiogram...
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29885751/epidemiology-of-pediatric-tuberculosis-in-kenya-and-risk-factors-for-mortality-during-treatment-a-national-retrospective-cohort-study
#17
Dickens Otieno Onyango, Courtney M Yuen, Enos Masini, Martien Willem Borgdorff
OBJECTIVES: To describe the epidemiology of childhood tuberculosis (TB) in Kenya, assess the magnitude of TB/human immunodeficiency virus (HIV) co-infection and identify risk factors for mortality during TB treatment. STUDY DESIGN: We conducted a retrospective analysis of the Kenyan national TB program data for patients enrolled from 2013 through 2015. A total of 23 753 children aged less than 15 years were included in the analysis. Survival analysis was performed with censorship at 9 months and mortality was the main outcome...
June 6, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29883655/pediatric-coronary-artery-bypass-surgery-for-congenital-heart-disease
#18
REVIEW
Soichiro Kitamura
BACKGROUND: Pediatric coronary artery bypass surgery (PCABS) for congenital heart disease has become increasingly important in infants and children undergoing modern cardiac surgery, because of its life-saving potential in unsuccessful coronary transfer surgery. This review summarizes the current surgical role of PCABS for treating congenital heart diseases. METHODS: Databases, mainly PUBMED, were searched for relevant publications regarding coronary bypass surgery in the pediatric population, from 1970 (commencement) to March 2018...
June 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29882415/acute-kidney-injury-in-children-with-acute-respiratory-failure
#19
Sindy M Villacrés, Shivanand S Medar, Scott I Aydin
BACKGROUND: Acute kidney injury (AKI) is common in critically ill children and develops in association with organ system dysfunction, with acute respiratory failure (ARF) one of the most common. We aim to study AKI in the pediatric ARF population. METHODS: Data were retrospectively collected on children aged 1 day to 18 years admitted to the pediatric intensive care unit (PICU) with ARF between 2010 and 2013. Descriptive statistics and multivariate analyses utilizing Mann-Whitney U, Wilcoxon signed rank, χ2 , or Fisher's exact tests were performed to identify risk factors associated with AKI...
June 1, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29879425/impact-of-a-h1n1-influenza-in-children-at-a-brazilian-university-hospital
#20
Gabriela Fontanella Biondo, João Carlos Santana, Patrícia M Lago, Jefferson Piva, Paulo Ricardo A Souza, Joana Genz Gaulke, Juliana M Sebben
BACKGROUND: A/H1N1 influenza is a viral disease that affects a significant part of the population mainly in winter, leading to increased number of medical consultations, hospitalizations and consequently care spending in emergency. METHODS: This is a case-series retrospective study, involving patients admitted to a tertiary hospital in southern Brazil in 2016 with a clinical diagnosis of acute respiratory infection of the influenza type and laboratory confirmation of influenza A/H1N1...
June 4, 2018: Brazilian Journal of Infectious Diseases
keyword
keyword
30862
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"