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Joaquín Ortego, Paul F Gugger, Victoria L Sork
Natural hybridization, which can be involved in local adaptation and in speciation processes, has been linked to different sources of anthropogenic disturbance. Here, we use genotypic data to study range-wide patterns of genetic admixture between the serpentine-soil specialist leather oak (Quercus durata) and the widespread Californian scrub oak (Quercus berberidifolia). First, we estimated hybridization rates and the direction of gene flow. Second, we tested the hypothesis that genetic admixture increases with different sources of environmental disturbance, namely anthropogenic destruction of natural habitats and wildfire frequency estimated from long-term records of fire occurrence...
September 13, 2016: New Phytologist
Sophie C H van Malderen, Tamas Szili-Torok, Sing C Yap, Sanne E Hoeks, Felix Zijlstra, Dominic A M J Theuns
BACKGROUND: After the introduction of the Biotronik Linox S/SD high-voltage lead, several cases of early failure have been observed. OBJECTIVE: The purpose of this article was to assess the performance of the Linox S/SD lead in comparison to 2 other contemporary leads. METHODS: We used the prospective Erasmus MC ICD registry to identify all implanted Linox S/SD (n = 408), Durata (St. Jude Medical, model 7122) (n = 340), and Endotak Reliance (Boston Scientific, models 0155, 0138, and 0158) (n = 343) leads...
August 2, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Enrico Mossello, David Simoni
High blood pressure and cognitive impairment often coexist in old age, but their pathophysiological association is complex. Several longitudinal studies have shown that high blood pressure at midlife is a risk factor for cognitive impairment and dementia, although this association is much less clear in old age. The effect of blood pressure lowering in reducing the risk of dementia is only borderline significant in clinical trials of older subjects, partly due to the insufficient follow-up time. Conversely, dementia onset is associated with a decrease of blood pressure values, probably secondary to neurodegeneration...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Corrado Magnani, Claudio Bianchi, Elisabetta Chellini, Dario Consonni, Bice Fubini, Valerio Gennaro, Alessandro Marinaccio, Massimo Menegozzo, Dario Mirabelli, Enzo Merler, Franco Merletti, Marina Musti, Enrico Oddone, Antonio Romanelli, Benedetto Terracini, Amerigo Zona, Carlo Zocchetti, Mariano Alessi, Antonio Baldassarre, Irma Dianzani, Milena Maule, Carolina Mensi, Stefano Silvestri
La III conferenza di consenso sul Mesotelioma Maligno della Pleura (MM) si è riunita il 29 Gennaio 2015. Questo rapporto presenta le conclusioni della sezione 'Epidemiologia, Sanità Pubblica e Medicina del Lavoro'. L'incidenza di MM nel 2011 in Italia è stata 3.64 per 100,000 persone/anno tra gli uomini e 1.32 tra le donne. I trends di incidenza nella popolazione sembrano non crescere ulteriormente. Dieci casi su cento sono associati ad esposizione non lavorativa. L'incidenza tra le donne è molto elevata in Italia, a causa sia di esposizione lavorativa sia non lavorativa...
November 2015: La Medicina del Lavoro
Anand D Shah, David S Hirsh, Jonathan J Langberg
Defibrillator lead malfunction can be a disastrous complication, leading to loss of protection from sudden cardiac death in a high-risk patient population. Recognition of lead-specific risk for failure can assist in development of focused screening or surveillance, as in the case of the Riata lead (St. Jude Medical, St. Paul, MN, USA) or the Sprint Fidelis lead (Medtronic Inc., Minneapolis, MN, USA). A case of defibrillation failure secondary to a Durata lead insulation failure is presented. A brief review of the literature and current St...
January 2016: Pacing and Clinical Electrophysiology: PACE
Anand D Shah, David S Hirsh, Jonathan J Langberg
BACKGROUND: Following increased rates of inside-out abrasion with the St Jude Medical Riata lead, the Durata implantable cardiac defibrillator (ICD) lead was introduced with modifications intended to increase abrasion resistance. Recent case reports have described insulation failures of the Durata. OBJECTIVE: To determine if increased rates of abrasion-related failure are present with the Durata lead. METHODS: The Food and Drug Administration Manufacturer and User Facility Device Experience database was queried for reports of insulation failure of the Durata lead from 2014...
December 2015: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Daniel B Kramer, Laura A Hatfield, Deepa McGriff, Christopher R Ellis, Melanie T Gura, Michelle Samuel, Linda Kallinen Retel, Robert G Hauser
BACKGROUND: As implantable cardioverter-defibrillator technology evolves, clinicians and patients need reliable performance data on current transvenous implantable cardioverter-defibrillator systems. In addition, real-world reliability data could inform postmarket surveillance strategies directed by regulators and manufacturers. METHODS AND RESULTS: We evaluated Medtronic Sprint Quattro, Boston Scientific Endotak, and St Jude Medical Durata and Riata ST Optim leads implanted by participating center physicians between January 1, 2006 and September 1, 2012...
June 2015: Journal of the American Heart Association
Gareth J Padfield, Christian Steinberg, Shahzad S Karim, Stanley Tung, Matthew T Bennett, John P Le Maitre, Jamil Bashir
INTRODUCTION: The Linox and Durata implantable cardioverter defibrillator (ICD) leads were introduced to British Columbia (BC) in 2008. We determined their performance and the potential risk factors for lead failure in a large population-based patient registry. METHODS AND RESULTS: We used the BC Cardiac Registry, a mandatory Governmental database of ICD implants, to identify all recipients of Linox and Durata leads in BC between October 2008 and April 2012, and those subsequently undergoing reoperation...
March 2015: Journal of Cardiovascular Electrophysiology
Ashish A Bhimani, Peerawut Deeprasertkul, Nischala Nannapaneni, George N Carayannopoulos
No abstract text is available yet for this article.
February 2015: Journal of Cardiovascular Electrophysiology
Adele Quartini, Annalisa Anastasia, Francesco Saverio Bersani, Claudia Melcore, Gabriella Albano, Chiara Colletti, Giuseppe Valeriani, Giuseppe Bersani
INTRODUCTION: Sleep disturbances have long been considered as a cardinal symptom of endogenous depression and dreams in depressed patients usually differ from those of healthy people. The aim of the present study was to investigate dream subjective experiences and their modifications in relation to clinical response in a group of escitalopram-treated depressed patients. METHODS: Twenty-seven female patients meeting DSM-IV-TR criteria for Major Depressive Disorder (MDD) and starting SSRI therapy were included in the study...
July 2014: Rivista di Psichiatria
Bharati Das, Sachin Yalagudri, S Maiya, Sunita Abhraham, J Kannan, Ravi Kishore
Late ICD lead perforation is an uncommon but clinically significant complication. The pathophysiology, predictors, clinical presentations and management although have been described earlier but still remain inconclusive. Our case highlights the challenges involved in clinical recognition, the value of CT scan in its diagnosis and need for careful management of this potentially life threatening condition. It is the first report on Durata lead perforation to the best of our knowledge.
July 2014: Indian Heart Journal
Fozia Z Ahmed, Stuart Allen, Mamas Mamas, Amir M Zaidi
The patented Optim coating was designed to prevent insulation abrasions on the Durata lead (St Jude Medical, St Paul, Minnesota) and avoid the problems that had afflicted its predecessor, the Riata silicone lead (St Jude Medical). We report a case of external insulation failure 8 months after implantation of a dual-coil Durata lead and consider the potential causes of the failure.
October 2014: Canadian Journal of Cardiology
John A Cairns, Andrew E Epstein, John Rickard, Stuart J Connolly, Christopher Buller, Bruce L Wilkoff, Janice Pogue, Ellison Themeles, Jeff S Healey
BACKGROUND: St Jude Medical Optim-insulated implantable cardioverter-defibrillator leads were designed to impart lubricity, strength, and abrasion resistance while maintaining flexibility and biostability. No long-term prospective follow-up data have been published. OBJECTIVE: The objective of this study was to determine the rates of all-cause mechanical failure and its subtypes (conductor fracture, insulation abrasion, externalized conductors, and other mechanical failures) in a prospective cohort of Optim-insulated implantable cardioverter-defibrillator leads...
December 2014: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Edward J Schloss, Mark E Krebs, Madhukar Gupta
No abstract text is available yet for this article.
October 2014: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Helen W Boucher, Mark Wilcox, George H Talbot, Sailaja Puttagunta, Anita F Das, Michael W Dunne
BACKGROUND: Dalbavancin, a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens, has a long plasma half-life, allowing for once-weekly dosing. DISCOVER 1 and DISCOVER 2 were identically designed noninferiority trials of dalbavancin for the treatment of acute bacterial skin and skin-structure infection. METHODS: We randomly assigned patients to receive dalbavancin intravenously on days 1 and 8 or vancomycin intravenously for at least 3 days with the option to switch to oral linezolid to complete 10 to 14 days of therapy...
June 5, 2014: New England Journal of Medicine
Jeffrey Liu, Genevieve Brumberg, Rohit Rattan, Divyang Patel, Evan Adelstein, Sandeep Jain, Samir Saba
Although implantable cardioverter defibrillator (ICD) leads are prone to failure and Food and Drug Administration recall, comprehensive longitudinal studies investigating contemporary ICD lead survival rate in the United States are lacking. All patients receiving Medtronic, Boston Scientific, or St. Jude Medical transvenous ICD leads at the hospitals of the University of Pittsburgh Medical Center from 2000 to 2012 were included. Leads were classified as (1) functional lead, patient deceased; (2) functional lead, replaced; (3) failed lead, replaced; or (4) functional lead, active...
January 1, 2014: American Journal of Cardiology
Kenneth A Ellenbogen, Bruce D Gunderson, Kurt D Stromberg, Charles D Swerdlow
BACKGROUND: The Lead Integrity Alert (LIA) was developed for Medtronic implantable cardioverter defibrillators to reduce inappropriate shocks for rapid oversensing caused by conductor fractures and reported for Medtronic Fidelis conductor fractures. The goal of this study was to compare the performance of LIA with conventional impedance monitoring for identifying lead system events (LSEs) and lead failures (LFs) in lead families that differ from Fidelis. METHODS AND RESULTS: We analyzed data from 12 793 LIA enabled implantable cardioverter-defibrillator and lead combinations including 6123 St...
December 2013: Circulation. Arrhythmia and Electrophysiology
Giovanni B Forleo, Luigi Di Biase, Germana Panattoni, Alessandro Politano, Giulia Magliano, Luca Santini, Andrea Natale, Francesco Romeo
AIMS: Serious concerns have been recently raised about the reliability of the silicone-polyurethane copolymer (Optim™) lead insulation system. We sought to identify insulation defects and Optim-lead failures by systematic fluoroscopic and electrical assessment in a prospectively defined cohort of implantable cardioverter-defibrillator (ICD) patients. METHODS AND RESULTS: Between July 2007 and December 2011, 234 patients were implanted with 413 optim-coated leads as part of an ICD system at a single centre...
February 2014: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Matthew T Bennett, Andrew C T Ha, Derek V Exner, Stanley K K Tung, Ratika Parkash, Sean Connors, Benoit Coutu, Eugene Crystal, Jean Champagne, Francois Philippon, Raymond Yee, Elizabeth A Stephenson, Pablo B Nery, Vidal Essebag, Shubhayan Sanatani, Damian Redfearn, Andrew D Krahn, Jeffrey S Healey
BACKGROUND: The St. Jude Medical Riata family of implantable cardioverter-defibrillator (ICD) leads has demonstrated a high rate of externalized conductors and electrical failure. OBJECTIVE: Given similar design elements of Durata to Riata, the purpose of this study was to assess the rates of failure of the Riata ST Optim and Durata lead families in Canada. METHODS: All Canadian ICD-implanting centers were invited to submit follow-up information on all Optim-coated ICD leads implanted...
October 2013: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Sam Hanon, Sean Mazer
No abstract text is available yet for this article.
October 2013: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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