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https://www.readbyqxmd.com/read/28720811/some-coral-diseases-track-climate-oscillations-in-the-caribbean
#1
C J Randall, R van Woesik
Disease outbreaks continue to reduce coral populations worldwide. Understanding coral diseases and their relationships with environmental drivers is necessary to forecast disease outbreaks, and to predict future changes in coral populations. Yet, the temporal dynamics of coral diseases are rarely reported. Here we evaluate trends and periodicities in the records of three common coral diseases (white-band disease, yellow-band disease, and dark-spot syndrome) that were surveyed between 1997 and 2014 at 2082 sites throughout the Caribbean...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28717231/a-connection-from-stratospheric-ozone-to-el-ni%C3%A3-o-southern-oscillation
#2
Desmond Manatsa, Geoffrey Mukwada
We use reanalysis and observational data to link the lower stratospheric ozone regulation of the ultraviolet radiation (UV-B) component of solar energy to ENSO modulation. Results indicate that during ENSO extremes, the Walker Circulation (WC) and Brewer Dobson Circulation are related to lower stratospheric ozone alterations east of the date line over the Pacific. These in turn are linked to upper tropospheric anomalous dipole temperature patterns on either side of the equator. The ensuing changes in geopotential height values do not only drive equatorial zonal wind anomalies in the upper troposphere that are reversed at the equatorial surface, but also impact on the intensity of the South Pacific High circulation...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28716986/development-of-protein-kinase-g-i%C3%AE-dimerizing-antihypertensive-drugs-are-we-standing-at-the-shore-of-the-rubicon
#3
EDITORIAL
Paula K Bautista-Niño, Anton J M Roks, A H Jan Danser
No abstract text is available yet for this article.
July 17, 2017: Hypertension
https://www.readbyqxmd.com/read/28713348/engineering-strategies-to-decode-and-enhance-the-genomes-of-coral-symbionts
#4
Rachel A Levin, Christian R Voolstra, Shobhit Agrawal, Peter D Steinberg, David J Suggett, Madeleine J H van Oppen
Elevated sea surface temperatures from a severe and prolonged El Niño event (2014-2016) fueled by climate change have resulted in mass coral bleaching (loss of dinoflagellate photosymbionts, Symbiodinium spp., from coral tissues) and subsequent coral mortality, devastating reefs worldwide. Genetic variation within and between Symbiodinium species strongly influences the bleaching tolerance of corals, thus recent papers have called for genetic engineering of Symbiodinium to elucidate the genetic basis of bleaching-relevant Symbiodinium traits...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28712964/on-the-use-of-non-steroidal-anti-inflammatory-drugs-as-rheology-modifiers-for-surfactant-solutions
#5
Pasquino Rossana, Bruno De Gennaro, Danila Gaudino, Nino Grizzuti
Surfactant molecules can give rise to different morphological structures, depending on numerous parameters such as temperature, surfactant concentration and salinity. Specifically, the salt content can be easily tuned in a way to induce morphological transitions and modulate the rheological response. It is shown that non steroidal anti-inflammatory drugs can be used in the same way as classical binding salts in changing the rheological properties of the resulting gel-like system. On the one hand, the experimental results show that by tuning small details in the molecular conformation of the drug and its concentration in the micellar solution it is possible to obtain the desired mechanical response...
July 13, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28712116/multi-century-tree-ring-precipitation-record-reveals-increasing-frequency-of-extreme-dry-events-in-the-upper-blue-nile-river-catchment
#6
Mulugeta Mokria, Aster Gebrekirstos, Abrham Abiyu, Meine Van Noordwijk, Achim Bräuning
Climate-related environmental and humanitarian crisis are important challenges in the Great Horn of Africa (GHA). In the absence of long-term past climate records in the region, tree-rings are valuable climate proxies, reflecting past climate variations and complementing climate records prior to the instrumental era. We established annually resolved multi-century tree-ring chronology from Juniperus procera trees in northern Ethiopia; the longest series yet for the GHA. The chronology correlates significantly with wet-season (r = 0...
July 16, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28711302/potential-selection-of-genetically-balanced-spermatozoa-based-on-the-hypo-osmotic-swelling-test-in-chromosomal-rearrangement-carriers
#7
Alexandre Rouen, Léa Carlier, Solveig Heide, Matthieu Egloff, Pauline Marzin, Flavie Ader, Mathias Schwartz, Eli Rogers, Nicole Joyé, Richard Balet, Nathalie Lédée, Laura Prat-Ellenberg, Nino Guy Cassuto, Jean-Pierre Siffroi
Chromosomal translocations and other balanced rearrangements, although usually associated with a normal phenotype, can lead to the transmission of an abnormal unbalanced genome to the offspring. Balanced and unbalanced spermatozoa, being indistinguishable, cannot be selected or deselected for prior to IVF and pre-implantation genetic diagnosis. Spermatozoa from 16 chromosomal rearrangement carriers were studied. After incubation in a hypo-osmotic solution (hypo-osmotic swelling test, or HOST), spermatozoa were fixed on microscope slides...
June 27, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28711167/perioperative-management-of-hypertensive-neuroblastoma-a-study-from-the-italian-group-of-pediatric-surgical-oncologists-gicop
#8
Luca Pio, Stefano Avanzini, Girolamo Mattioli, Giuseppe Martucciello, Angela Rita Sementa, Massimo Conte, Annarita Gigliotti, Claudio Granata, Ernesto Leva, Anna Maria Fagnani, Umberto Caccioppoli, Nino Tedesco, Jurgen Schleef, Elisa Tirtei, Fortunato Siracusa, Paolo D'Angelo, Pierluigi Lelli Chiesa, Lucia Miglionico, Bruno Noccioli, Elisa Severi, Claudio Carlini, Francesco Vaccarella, Francesco Camoglio, Simone Cesaro, Alessandra Narciso, Giovanna Riccipetitoni, Giovanni Cecchetto, Alessandro Inserra
BACKGROUND: Hypertension (HT) is rarely reported in patients affected by Neuroblastoma (NB), and management guidelines are lacking. Clinical features and perioperative medical treatment in such patients were reviewed to 1) ascertain whether a shared treatment strategy exists among centers and 2) if possible, propose some recommendations for the perioperative management of HT in NB patients. METHODS: A retrospective multicenter survey was conducted on patients affected by NB who presented HT symptoms...
July 3, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28708605/modal-analysis-of-annual-runoff-volume-and-sediment-load-in-the-yangtze-river-lake-system-for-the-period-1956-2013
#9
Huai Chen, Lijun Zhu, Jianzhong Wang, Hongxia Fan, Zhihuan Wang
This study focuses on detecting trends in annual runoff volume and sediment load in the Yangtze river-lake system. Times series of annual runoff volume and sediment load at 19 hydrological gauging stations for the period 1956-2013 were collected. Based on the Mann-Kendall test at the 1% significance level, annual sediment loads in the Yangtze River, the Dongting Lake and the Poyang Lake were detected with significantly descending trends. The power spectrum estimation indicated predominant oscillations with periods of 8 and 20 years are embedded in the runoff volume series, probably related to the El Niño Southern Oscillation (2-7 years) and Pacific Decadal Oscillation (20-30 years)...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28699997/accuracy-of-a-pediatric-early-warning-score-in-the-recognition-of-clinical-deterioration
#10
Juliana de Oliveira Freitas Miranda, Climene Laura de Camargo, Carlito Lopes Nascimento, Daniel Sales Portela, Alan Monaghan
Objective: to evaluate the accuracy of the version of the Brighton Pediatric Early Warning Score translated and adapted for the Brazilian context, in the recognition of clinical deterioration. Method: a diagnostic test study to measure the accuracy of the Brighton Pediatric Early Warning Score for the Brazilian context, in relation to a reference standard. The sample consisted of 271 children, aged 0 to 10 years, blindly evaluated by a nurse and a physician, specialists in pediatrics, with interval of 5 to 10 minutes between the evaluations, for the application of the Brighton Pediatric Early Warning Score for the Brazilian context and of the reference standard...
July 10, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28694477/realism-of-modelled-indian-summer-monsoon-correlation-with-the-tropical-indo-pacific-affects-projected-monsoon-changes
#11
Ziguang Li, Xiaopei Lin, Wenju Cai
El Niño-Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) tend to exert an offsetting impact on Indian summer monsoon rainfall (ISMR), with an El Niño event tending to lower, whereas a positive IOD tending to increase ISMR. Simulation of these relationships in Phase Five of the Coupled Model Intercomparison Project has not been fully assessed, nor is their impact on the response of ISMR to greenhouse warming. Here we show that the majority of models simulate an unrealistic present-day IOD-ISMR correlation due to an overly strong control by ENSO...
July 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28685758/greening-of-the-sahara-suppressed-enso-activity-during-the-mid-holocene
#12
Francesco S R Pausata, Qiong Zhang, Francesco Muschitiello, Zhengyao Lu, Léon Chafik, Eva M Niedermeyer, J Curt Stager, Kim M Cobb, Zhengyu Liu
The evolution of the El Niño-Southern Oscillation (ENSO) during the Holocene remains uncertain. In particular, a host of new paleoclimate records suggest that ENSO internal variability or other external forcings may have dwarfed the fairly modest ENSO response to precessional insolation changes simulated in climate models. Here, using fully coupled ocean-atmosphere model simulations, we show that accounting for a vegetated and less dusty Sahara during the mid-Holocene relative to preindustrial climate can reduce ENSO variability by 25%, more than twice the decrease obtained using orbital forcing alone...
July 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/28685248/genetic-risk-factors-for-myocardial-infarction-more-clearly-manifest-for-early-age-of-first-onset
#13
Boris V Titov, German J Osmak, Natalia A Matveeva, Nino G Kukava, Roman M Shakhnovich, Alexander V Favorov, Mikhail Ya Ruda, Olga O Favorova
Epidemiological genetics established that heritability in determining the risk of myocardial infarction (MI) is substantially greater when MI occurs early in life. However, the genetic architecture of early-onset and late-onset MI was not compared. We analyzed genotype frequencies of SNPs in/near 20 genes whose protein products are involved in the pathogenesis of atherosclerosis in two groups of Russian patients with MI: the first group included patients with age of first MI onset <60 years (N = 230) and the second group with onset ≥60 years (N = 174)...
July 6, 2017: Molecular Biology Reports
https://www.readbyqxmd.com/read/28685178/time-based-event-expectancies-in-children-with-autism-spectrum-disorder
#14
Marina Kunchulia, Tamari Tatishvili, Nino Lomidze, Khatuna Parkosadze, Roland Thomaschke
Here, we studied the time-based event expectancies in children with Autism spectrum disorder. Nine children with Autism spectrum disorders and ten (6-11 years) typically developing children participated. In a choice-response task with two different pre-target intervals, participants had to indicate the left or right direction of a target stimulus. The target was predicted by the duration of the pre-target interval with 80% validity. We found that, in children with Autism spectrum disorder, in contrast to typically developing children, the formation of time-based event expectancies was restricted to the relatively longer pre-target interval...
July 6, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28684863/bcl3-a-regulator-of-nf-%C3%AE%C2%BAb-inducible-by-tweak-in-acute-kidney-injury-with-anti-inflammatory-and-antiapoptotic-properties-in-tubular-cells
#15
Jonay Poveda, Ana B Sanz, Susana Carrasco, Marta Ruiz-Ortega, Pablo Cannata-Ortiz, Maria D Sanchez-Niño, Alberto Ortiz
Acute kidney injury (AKI) is characterized by tubular cell death and interstitial inflammation. TWEAK promotes experimental kidney injury and activates the transcription factor NF-κB, a key regulator of genes involved in cell survival and inflammatory response. In search of potential therapeutic targets for AKI, we compared a transcriptomics database of NF-κB-related genes from murine AKI-kidneys with a transcriptomics database of TWEAK-stimulated cultured tubular cells. Four out of twenty-four (17%) genes were significantly upregulated (false discovery rate, FDR<0...
July 7, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/28684673/localization-of-fibrinogen-in-the-vasculo-astrocyte-interface-after-cortical-contusion-injury-in-mice
#16
Nino Muradashvili, Suresh C Tyagi, David Lominadze
Besides causing neuronal damage, traumatic brain injury (TBI) is involved in memory reduction, which can be a result of alterations in vasculo-neuronal interactions. Inflammation following TBI is involved in elevation of blood content of fibrinogen (Fg), which is known to enhance cerebrovascular permeability, and thus, enhance its deposition in extravascular space. However, the localization of Fg in the extravascular space and its possible interaction with nonvascular cells are not clear. The localization of Fg deposition in the extravascular space was defined in brain samples of mice after cortical contusion injury (CCI) and sham-operation (control) using immunohistochemistry and laser-scanning confocal microscopy...
July 6, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28681837/el-ni%C3%A3-o-like-teleconnection-increases-california-precipitation-in-response-to-warming
#17
Robert J Allen, Rainer Luptowitz
Future California (CA) precipitation projections, including those from the most recent Climate Model Intercomparison Project (CMIP5), remain uncertain. This uncertainty is related to several factors, including relatively large internal climate variability, model shortcomings, and because CA lies within a transition zone, where mid-latitude regions are expected to become wetter and subtropical regions drier. Here, we use a multitude of models to show CA may receive more precipitation in the future under a business-as-usual scenario...
July 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/28678907/the-effect-of-a-self-constructed-material-on-children-s-physical-activity-during-recess
#18
Antonio Méndez-Giménez, José-Antonio Cecchini, Javier Fernández-Río
OBJECTIVE: To analyze whether an intervention supported by free play with a self-constructed material increases the level of physical activity of students during recess. METHODS: The participants were 166 children of third to sixth grade, between nine and 12 years old (average = 10.64; SS = 1.13). An experimental project was conducted with pre-test and post-test measurement, and a control group. Experimental group participants built cardboard paddles (third and fourth) and flying rings (fifth and sixth), a material they used freely for one week during recess...
June 26, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28674917/fire-distribution-in-peninsular-malaysia-sumatra-and-borneo-in-2015-with-special-emphasis-on-peatland-fires
#19
Jukka Miettinen, Chenghua Shi, Soo Chin Liew
In this paper, we analyze the spatio-temporal distribution of vegetation fires in Peninsular Malaysia, Sumatra, and Borneo in the severe El Niño year of 2015, concentrating on the distribution of fires between mineral soils and peatland areas, and between land cover types in peatland areas. The results reveal that 53% of all Moderate Resolution Imaging Spectroradiometer (MODIS) fire detections were recorded in peatlands that cover only 12% of the study area. However, fire occurrence in the peatland areas was highly dependent on land cover type...
July 3, 2017: Environmental Management
https://www.readbyqxmd.com/read/28674455/heterologous-expression-of-the-yeast-tpo1p-or-pdr5p-membrane-transporters-in-arabidopsis-confers-plant-xenobiotic-tolerance
#20
Estelle Remy, María Niño-González, Cláudia P Godinho, Tânia R Cabrito, Miguel C Teixeira, Isabel Sá-Correia, Paula Duque
Soil contamination is a major hindrance for plant growth and development. The lack of effective strategies to remove chemicals released into the environment has raised the need to increase plant resilience to soil pollutants. Here, we investigated the ability of two Saccharomyces cerevisiae plasma-membrane transporters, the Major Facilitator Superfamily (MFS) member Tpo1p and the ATP-Binding Cassette (ABC) protein Pdr5p, to confer Multiple Drug Resistance (MDR) in Arabidopsis thaliana. Transgenic plants expressing either of the yeast transporters were undistinguishable from the wild type under control conditions, but displayed tolerance when challenged with the herbicides 2,4-D and barban...
July 3, 2017: Scientific Reports
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