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Daniel J Southwell, Shane A Petersen, Tyson A C Beach, Ryan B Graham
Altering footwear worn during performance of the barbell back squat has been shown to change motion patterns, but it is not completely understood how this affects biomechanical loading demands. The primary objective was to compare lower back and extremity net joint moments in 24 experienced weightlifters (12M, 12F) who performed 80% one-repetition maximum back squats under three different footwear conditions (barefoot, running shoes, weightlifting shoes). Results showed that there was a significant main effect of footwear condition on the knee extension moment (p=0...
October 12, 2016: Journal of Electromyography and Kinesiology
Daniel Lordelo San Martin, Dislene Nascimento Dos Santos, Abrahão Fontes Baptista
OBJECTIVE: To describe the pain in patients infected with human T-cell lymphotropic virus type 1, clinically and epidemiologically. METHODS: This systematic review was based on The PRISMA Statement. Four reviewers searched PUBMED, SciELO, LILACS and BIREME for data from observational studies and clinical trials (n≥30) regarding pain prevalence, characteristics, and associated factors in patients with human T-cell lymphotropic virus type 1. No limits on publication date or language were established...
October 18, 2016: Brazilian Journal of Infectious Diseases
Shang-Ju Li, Abraham Flaxman, Riyadh Lafta, Lindsay Galway, Tim K Takaro, Gilbert Burnham, Amy Hagopian
OBJECTIVES: We estimated war-related Iraqi mortality for the period 1980 through 1993. METHOD: To test our hypothesis that deaths reported by siblings (even dating back several decades) would correspond with war events, we compared sibling mortality reports with the frequency of independent news reports about violent historic events. We used data from a survey of 4,287 adults in 2000 Iraqi households conducted in 2011. Interviewees reported on the status of their 24,759 siblings...
2016: PloS One
Xiaoran Duan, Yongli Yang, Shanjuan Tan, Sihua Wang, Xiaolei Feng, Liuxin Cui, Feifei Feng, Songcheng Yu, Wei Wang, Yongjun Wu
The purpose of the study was to explore the application of artificial neural network model in the auxiliary diagnosis of lung cancer and compare the effects of back-propagation (BP) neural network with Fisher discrimination model for lung cancer screening by the combined detections of four biomarkers of p16, RASSF1A and FHIT gene promoter methylation levels and the relative telomere length. Real-time quantitative methylation-specific PCR was used to detect the levels of three-gene promoter methylation, and real-time PCR method was applied to determine the relative telomere length...
October 20, 2016: Medical & Biological Engineering & Computing
Alexandros Stamatopoulos, Davide Patrini, Efstratios Koletsis, Elaine Borg, Reena Khiroja, Martin Hayward, David Lawrence, Nikolaos Panagiotopoulos
IgG4-related disease (IgG4-RD) is a fibroinflammatory condition that can affect practically every organ. Although it was first identified in pancreas and salivary glands, major organs like liver, biliary tree, kidney, thyroid glands and lungs are commonly involved, sometimes resulting in organ failure. We describe a case of an 41-year-old man presented with back pain after a rotator cuff injury. A Computed Tomography (CT) revealed incidentally a right lower lobe paravertebral lesion extending across the T5 and T6 vertebral levels and invading into the adjacent pleural surface...
2016: Respiratory Medicine Case Reports
Faisal R Jahangiri, Sami Al Eissa, Samir Sayegh, Fahad Al Helal, Shomoukh A Al-Sharif, Monerah M Annaim, Sheryar Muhammad, Tanweer Aziz
A 16-year-old male patient with Ehler-Danlos syndrome (EDS) and a back deformity since birth presented with severe kyphoscoliosis. The patient was neurologically intact but had respiratory and cardiac insufficiencies. A two-stage vertebral column resection (VCR) at T9-T10 with multiple level fusion with multimodality intraoperative neurophysiological monitoring (IONM) was planned.  During the first stage, pedicle screws were placed at multiple spinal levels above and below the VCR level. Upper and lower somatosensory evoked potentials (SSEP), transcranial electrical motor evoked potentials (TCeMEP), and electromyography were monitored continuously and showed no significant changes...
August 31, 2016: Curēus
Clare F Heisey, J Derek Kingsley
Static stretching was once recognized as a method of preparation for physical activity that would inhibit performance and increase risk of injury. However, a growing body of research suggests that static stretching may not have an inhibitory effect. Regardless, the data have not examined gender differences or the fatigue index (FI) and flexibility effects of static stretching on the back squat over multiple sets. Therefore, the purpose of this study was to examine the relationship between a static-stretch condition (SC) and control condition (CC) on flexibility and the FI of Division I female athletes during 4 sets of the back squat...
2016: International Journal of Exercise Science
Mohamad Bydon, Mohamed Macki, Panagiotis Kerezoudis, Daniel M Sciubba, Jean-Paul Wolinsky, Timothy F Witham, Ziya L Gokaslan, Ali Bydon
INTRODUCTION: The objective of this study is to determine the incidence and prognostic factors of adjacent segment disease (ASD) following first-time lumbar discectomy (LD). METHODS: We retrospectively reviewed all neurosurgical patients who underwent first-time LD for degenerative lumbar disease from 1990 to 2012. ASD was defined as a clinical and radiographic progression of degenerative spinal disease that required surgical decompression (with or without fusion) at the level above or below the index discectomy...
October 17, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Tao Wang, Yong Zhou, Chong Lei, Shaotao Zhi, Lei Guo, Hengyu Li, Zhizheng Wu, Shaorong Xie, Jun Luo, Huayan Pu
The disturbing effect of the stray magnetic fields of Fe-based amorphous ribbons on the giant magnetoimpedance (GMI) sensor has been investigated systematically in this paper. Two simple methods were used for examining the disturbing effect of the stray magnetic fields of ribbons on the GMI sensor. In order to study the influence of the stray magnetic fields on the GMI effect, the square-shaped amorphous ribbons were tested in front, at the back, on the left and on the top of a meander-line GMI sensor made up of soft ferromagnetic films, respectively...
October 17, 2016: Sensors
Linda Chang, Gro C Løhaugen, Tamara Andres, Caroline S Jiang, Vanessa Douet, Naomi Tanizaki, Christina Walker, Deborrah Castillo, Ahnate Lim, Jon Skranes, Chad Otoshi, Eric N Miller, Thomas M Ernst
OBJECTIVES: We aimed to evaluate the effectiveness of an adaptive-working memory training (WMT) program, the corresponding neural correlates, and LMX1A-rs4657412 polymorphism on the adaptive-WMT, in HIV-participants compared to seronegative controls (SN). METHODS: 201/206 qualified participants completed baseline assessments before randomization to 25-sessions of adaptive-WMT or non-adaptive-WMT. 74/76 (34HIV, 42SN) completed adaptive-WMT and all 40 completed non-adaptive-WMT (20HIV, 20SN) and were assessed after 1-month, and 55 adaptive-WMT-participants were also assessed after 6-months...
October 19, 2016: Annals of Neurology
K H N Weerdesteijn, F G Schaafsma, A J van der Beek, J R Anema
Purpose The purpose of this study was to obtain consensus among physicians of several medical specialties on the level of limitations to work-related functioning of people with persistent "medically unexplained" physical symptoms (PPS). Methods A modified Delphi study was conducted with 15 physicians of five different medical specialties. The study involved two email rounds and one meeting. In each round, the physicians prioritized the level of limitations in 78 work-related functioning items for four different PPS cases...
October 19, 2016: Journal of Occupational Rehabilitation
Tatsuya Umemoto, Takeshi Nomoto, Satoshi Kuroda, Takahiro Ogawa, Kentaro Nagao, Yuki Shimizu, Nobuyuki Nakajima, Hakushi Kim, Masahiro Nitta, Kazuya Hanai, Akio Hoshi, Toshiro Terachi
A 40-year-old woman was referred to our hospital with right lower back pain as the chief complaint. Contrast-enhanced computed tomography (CT) showed a partially-solid tumor within a cyst measuring approximately 6 cm in diameter in the right renal hilum. The solid part was enhanced in the early phase and contrast medium was washed out earlier in the solid part than in the parenchyma in the equilibrium phase. Plain CT revealed partial cyst wall calcification. A soft tissue shadow approximately 10 mm in diameter in the dorsal inferior vena cava at the upper pole of the kidney and a solid tumor adjacent to the iliopsoas muscle and the kidney were detected...
September 2016: Hinyokika Kiyo. Acta Urologica Japonica
Mengmeng Wang, Amanda K Kussrow, Mireia Fernandez Ocana, Jeffrey R Chabot, Christopher S Lepsy, Darryl J Bornhop, Denise M O'Hara
BACKGROUND AND PURPOSE: A monoclonal antibody (PF-00547659) against Mucosal Adressin Cell Adhesion Molecule (MAdCAM), expressed as both soluble (sMAdCAM) and trans-membrane (mMAdCAM) target forms, showed over 30-fold difference in antibody-target KD between in vitro (Biacore) and clinically derived (KD,in-vivo ) values. Back-scattering interferometry (BSI) was applied to acquire physiologically relevant KD values which were used to establish in vitro and in vivo correlation (IVIVC). EXPERIMENTAL APPROACH: Back-scattering interferometry (BSI) was applied to obtain KD values between PF-00547659 and recombinant human MAdCAM in buffer or CHO cells and endogenous MAdCAM in human serum or colon tissue...
October 19, 2016: British Journal of Pharmacology
Silje E Reme, Torill H Tveito, Anette Harris, Stein Atle Lie, Astrid Grasdal, Aage Indahl, Jens Ivar Brox, Tone Tangen, Eli Molde Hagen, Sigmund Gismervik, Arit Ødegård, Livar Fryland, Egil A Fors, Trudie Chalder, Hege R Eriksen
STUDY DESIGN: A randomized controlled trial. OBJECTIVE: The aim of this study was to evaluate whether a tailored and manualized cognitive behavior therapy (CBT) or nutritional supplements of seal oil and soy oil had any additional benefits over a brief cognitive intervention (BI) on return to work (RTW). SUMMARY OF BACKGROUND DATA: Brief intervention programs are clinically beneficial and cost-effective for patients with low back pain (LBP)...
October 15, 2016: Spine
Yoshiaki Suzuki, Susumu Ohya, Hisao Yamamura, Wayne R Giles, Yuji Imaizumi
Large-conductance Ca(2+)-activated K(+) (BK) channels play essential roles in both excitable and non-excitable cells. For example, in chondrocytes, agonist-induced Ca(2+) release from intracellular store activates BK channels, and this hyperpolarizes these cells, augments Ca(2+) entry, and forms a positive feed-back mechanism for Ca(2+) signaling and stimulation-secretion coupling. In the present study, functional roles of a newly identified splice variant in the BK channel α subunit (BKαΔe2) were examined in a human chondrocyte cell line, OUMS-27, and in a HEK293 expression system...
October 7, 2016: Journal of Biological Chemistry
C Ramírez-Maestre, R Esteve, G Ruiz-Párraga, L Gómez-Pérez, A E López-Martínez
PURPOSE: This study investigated the role of anxiety sensitivity, resilience, pain catastrophizing, depression, pain fear-avoidance beliefs, and pain intensity in patients with acute back pain-related disability. METHOD: Two hundred and thirty-two patients with acute back pain completed questionnaires on anxiety sensitivity, resilience, pain catastrophizing, fear-avoidance beliefs, depression, pain intensity, and disability. RESULTS: A structural equation modelling analysis revealed that anxiety sensitivity was associated with pain catastrophizing, and resilience was associated with lower levels of depression...
October 18, 2016: International Journal of Behavioral Medicine
Ghasem-Sam Toloo, Peter Aitken, Julia Crilly, Gerry FitzGerald
BACKGROUND: Patients attending hospital emergency departments (ED) commonly cite the urgency and severity of their condition as the main reason for choosing the ED. However, the patients' perception of urgency and severity may be different to the nurses' perception of their urgency and severity, which is underpinned by their professional experience, knowledge, training and skills. This discordance may be a cause of patient dissatisfaction. The purpose of this study is to understand the extent of agreement/disagreement between the patient's perceived priority and actual triage category and associated factors...
October 18, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
DeMetris D Reed, Lee-Anne J Walter, Angela N Schmitz, Daniel E Guadián-García, Ty E Lawrence
Palatability attributes of beef striploin steaks mechanically enhanced with pork fat were evaluated. Striploins were collected from USDA Standard steer carcasses, longitudinally cut into halves (lateral or medial) and assigned randomly to pork fat injection (PFI) or non-injected control (CON). Loin halves assigned to PFI were enhanced with pork fat using a multi-needle injector. Steaks were analyzed via Warner-Bratzler shear force, trained and consumer sensory panels, and proximate analysis (cooked and uncooked)...
October 5, 2016: Meat Science
Hideaki Kaneko, Shuo Zhang, Miho Sekiguchi, Takuya Nikaido, Koshi Makita, Jiro Kurata, Shin-Ichi Konno
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To evaluate activity of the nucleus accumbens (NAc) in response to lumbar mechanical stimulation in patients with chronic low back pain (cLBP) using functional magnetic resonance imaging (fMRI). SUMMARY OF BACKGROUND DATA: Although a modified activity of the NAc was characterized in cLBP patients, its pathological significance has yet to be determined. We hypothesized that NAc activation in response to pain might differ depending on the extent of psychiatric problems, which might be associated with the affective/motivational background of chronic pain...
October 17, 2016: Spine
Ickpyo Hong, Heather S Bonilha
The aim of this study was to provide a systematic review of psychometric studies of upper extremity (UE) outcome measures validated by Rasch analysis and assess the extent to which their measurement areas cover the domains of the International Classification of Functioning, Disability and Health model. A literature search from 1966 to 2014 was performed using PubMed, CINAHL, Scopus, PsycINFO, Ovid/MEDLINE, ERIC, and Cochrane library. Fourteen keywords indicating 'upper extremity', 'psychometric properties', and 'outcome measures' were used...
October 14, 2016: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
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