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https://www.readbyqxmd.com/read/28329492/folliculocentric-tinea-versicolor
#1
Andrew Hudson, Bryan Carroll, Soo Jung Kim
Tinea versicolor (TV) is typically an asymptomaticfungal infection of the stratum corneum owingto Malassezia overgrowth. It presents as hypoorhyperpigmented macules with fine scale thatcoalesce into patches on the trunk, neck, and/or arms.Presented in this report is a 34-year-old man with aninteresting case of folliculocentric tinea versicolormanifesting as perifollicular hypopigmented maculeson the lower back.
February 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329241/lipoprotein-a-the-revenant
#2
Baris Gencer, Florian Kronenberg, Erik S Stroes, François Mach
In the mid-1990s, the days of lipoprotein(a) [Lp(a)] were numbered and many people would not have placed a bet on this lipid particle making it to the next century. However, genetic studies brought Lp(a) back to the front-stage after a Mendelian randomization approach used for the first time provided strong support for a causal role of high Lp(a) concentrations in cardiovascular disease and later also for aortic valve stenosis. This encouraged the use of therapeutic interventions to lower Lp(a) as well numerous drug developments, although these approaches mainly targeted LDL cholesterol, while the Lp(a)-lowering effect was only a 'side-effect'...
February 17, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28329000/trajectory-formation-principles-are-the-same-after-mild-or-moderate-stroke
#3
Denis Mottet, Liesjet Elisabeth Henriette van Dokkum, Jérôme Froger, Abdelkader Gouaïch, Isabelle Laffont
When we make rapid reaching movements, we have to trade speed for accuracy. To do so, the trajectory of our hand is the result of an optimal balance between feed-forward and feed-back control in the face of signal-dependant noise in the sensorimotor system. How far do these principles of trajectory formation still apply after a stroke, for persons with mild to moderate sensorimotor deficits who recovered some reaching ability? Here, we examine the accuracy of fast hand reaching movements with a focus on the information capacity of the sensorimotor system and its relation to trajectory formation in young adults, in persons who had a stroke and in age-matched control participants...
2017: PloS One
https://www.readbyqxmd.com/read/28328589/cervical-retrograde-spinal-cord-stimulation-lead-placement-to-treat-failed-back-surgery-syndrome-a-case-report
#4
Noud van Helmond, Caroline N Kardaszewski, Kenneth B Chapman
Spinal cord stimulation is an effective treatment modality for refractory neuropathic pain conditions, but the placement of leads can be challenging due to unforeseen anatomical variations. We used a retrograde C7-T1 approach to place a lead at the bottom of T8 in a patient suffering from failed back surgery syndrome. We were able to achieve adequate stimulation in her lower back and legs, which resulted in significant reduction in pain intensity during the spinal cord stimulation trial. Cervical retrograde placement of leads may represent an alternative method for successful placement of percutaneous leads in patients with abnormal anatomy due to thoracic postsurgical changes...
March 15, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28328011/when-emotional-pain-becomes-physical-adverse-childhood-experiences-pain-and-the-role-of-mood-and-anxiety-disorders
#5
Natalie J Sachs-Ericsson, Julia L Sheffler, Ian H Stanley, Jennifer R Piazza, Kristopher J Preacher
OBJECTIVE: We examined the association between retrospective reports of adverse childhood experiences (ACEs) and painful medical conditions. We also examined the mediating and moderating roles of mood and anxiety disorders in the ACEs-painful medical conditions relationship. METHOD: Ten-year longitudinal data were obtained from the National Comorbidity Surveys (NCS-1, NCS-2; N = 5001). The NCS-1 obtained reports of ACEs, current health conditions, current pain severity, and mood and anxiety disorders...
March 22, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28326305/implications-for-a-stem-cell-regenerative-medicine-based-approach-to-human-intervertebral-disk-degeneration
#6
REVIEW
Petra Kraus, Thomas Lufkin
The human body develops from a single cell, the zygote, the product of the maternal oocyte and the paternal spermatozoon. That 1-cell zygote embryo will divide and eventually grow into an adult human which is comprised of ~3.7 × 10(13) cells. The tens of trillions of cells in the adult human can be classified into approximately 200 different highly specialized cell types that make up all of the different tissues and organs of the human body. Regenerative medicine aims to replace or restore dysfunctional cells, tissues and organs with fully functional ones...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28325585/gender-differences-in-demographic-and-clinical-correlates-among-veterans-with-musculoskeletal-disorders
#7
Diana M Higgins, Brenda T Fenton, Mary A Driscoll, Alicia A Heapy, Robert D Kerns, Matthew J Bair, Constance Carroll, Penny L Brennan, Diana J Burgess, John D Piette, Sally G Haskell, Cynthia A Brandt, Joseph L Goulet
BACKGROUND: Studies suggest that women may be at greater risk for developing chronic pain and pain-related disability. METHODS: Because musculoskeletal disorders (MSD) are the most frequently endorsed painful conditions among veterans, we sought to characterize gender differences in sociodemographic and clinical correlates among veterans upon entry into Veterans Health Administration's Musculoskeletal Disorders Cohort (n = 4,128,008). RESULTS: Women were more likely to be younger, Black, unmarried, and veterans of recent conflicts...
March 18, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28325067/deep-genealogical-analysis-of-a-large-cohort-of-participants-in-the-cartagene-project-quebec-canada
#8
Marc Tremblay, Gabrielle Rouleau
BACKGROUND: Genealogical analysis helps to better understand the genetic structure of populations. The population of Quebec (Canada) often serves as a model for this type of analysis, having one of the world's most complete genealogical databases. AIM: The main objective of this study was to reconstruct, analyse and compare the ascending genealogies of participants to CARTaGENE, a project that aims at building a database on various aspects of public health. SUBJECTS AND METHODS: In total, 5110 genealogies from four Quebec regions were reconstructed...
March 21, 2017: Annals of Human Biology
https://www.readbyqxmd.com/read/28323709/single-stage-transpedicular-vertebrectomy-and-expandable-cage-placement-for-treatment-of-unstable-mid-and-lower-lumbar-burst-fractures
#9
Jong-Il Choi, Bum-Joon Kim, Sung-Kon Ha, Sang-Dae Kim, Dong-Jun Lim, Se-Hoon Kim
STUDY DESIGN: Retrospective clinical and radiographic study. OBJECTIVE: To examine the efficacy and safety of vertebrectomy and expandable cage placement by a single-stage posterior approach for unstable mid and lower lumbar burst fractures (below the L3). SUMMARY OF BACKGROUND DATA: Patients with unstable mid and lower lumbar burst fractures require surgical treatment to relieve pain, address paralysis, and stabilize the spine to prevent further segmental deformity...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323692/hyperlordosis-is-associated-with-facet-joint-pathology-at-the-lower-lumbar-spine
#10
Thorsten Jentzsch, James Geiger, Matthias A König, Clément M L Werner
STUDY DESIGN: A retrospective study. OBJECTIVE: Our study opted to clarify the remaining issues of lumbar lordosis (LL) with regard to (1) its physiological values, (2) age, (3) sex, and (4) facet joint (FJ) arthritis and orientation using computed tomography (CT) scans. SUMMARY OF BACKGROUND DATA: Recent studies have questioned whether LL really decreases with age, but study sample sizes have been rather small and mostly been based on x-rays...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28322966/influence-of-different-molar-concentrations-of-acid-on-morphological-physicochemical-and-pasting-properties-of-pakistani-basmati-and-irri-rice-starches
#11
Abeera Moin, Tahira Mohsin Ali, Abid Hasnain
Starches extracted from two dominant varieties of rice, Basmati and Irri were subjected to acid hydrolysis by preparing starch slurry of 35% (w/v) in HCl solutions of concentrations 0.1M, 0.3M and 0.8M. The scanning electron micrographs showed that granular morphology of starches significantly changed after acid hydrolysis. Acid thinning improved the solubility of starches whereas decline was observed in swelling power and water retention capacity. Paste clarity of both acid treated Basmati and Irri rice starches reduced gradually upon cold storage...
March 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28322742/potassium-channel-abnormalities-are-consistent-with-early-axon-degeneration-of-motor-axons-in-the-g127x-sod1-mouse-model-of-amyotrophic-lateral-sclerosis
#12
Rikke Maglemose, Anne Hedegaard, Janna Lehnhoff, Kristina Petrova Dimintiyanova, Mihai Moldovan, Lillian Grøndahl, Claire Francesca Meehan
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease, which selectively affects upper and lower motoneurones. The underlying pathophysiology of the disease is complex but electrophysiological studies of peripheral nerves in ALS patients as well as human autopsy studies indicate that a potassium channel dysfunction/loss is present early in the symptomatic phase. It remains unclear to what extent potassium channel abnormalities reflect a specific pathogenic mechanism in ALS. The aim of this study was therefore to investigate the temporal changes in the expression and/or function of potassium channels in motoneurones in the adult G127X SOD1 mouse model of ALS, a model which has a very long presymptomatic phase...
March 16, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28322477/impact-of-insurance-provider-on-overall-costs-in-failed-back-surgery-syndrome-a-cost-study-of-122-827-patients
#13
Aladine A Elsamadicy, Samuel Harrison Farber, Siyun Yang, Syed Mohammed Qasim Hussaini, Kelly R Murphy, Amanda Sergesketter, Carter M Suryadevara, Promila Pagadala, Beth Parente, Jichun Xie, Shivanand P Lad
OBJECTIVES: Failed back surgery syndrome (FBSS) affects 40% of patients following spine surgery with estimated costs of $20 billion to the US health care system. The aim of this study was to assess the cost differences across the different insurance providers for FBSS patients. METHODS: A retrospective longitudinal study was performed using the Truven MarketScan(®) database to identify FBSS patients from 2001 to 2012. Patients were grouped into Commercial, Medicaid, or Medicare cohorts...
March 21, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28322213/chronic-monitoring-of-lower-urinary-tract-activity-via-a-sacral-dorsal-root-ganglia-interface
#14
Abeer Khurram, Shani Ross, Zachariah Sperry, Aileen Ouyang, Christopher Stephan, Ahmad Jiman, Tim M Bruns
OBJECTIVE: Our goal is to develop an interface that integrates chronic monitoring of lower urinary tract (LUT) activity with stimulation of peripheral pathways. APPROACH: Penetrating microelectrodes were implanted in sacral dorsal root ganglia (DRG) of adult male felines. Peripheral electrodes were placed on or in the pudendal nerve, bladder neck and near the external urethral sphincter. Supra-pubic bladder catheters were implanted for saline infusion and pressure monitoring...
March 21, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28319133/effects-of-sudden-walking-perturbations-on-neuromuscular-reflex-activity-and-three-dimensional-motion-of-the-trunk-in-healthy-controls-and-back-pain-symptomatic-subjects
#15
Juliane Mueller, Tilman Engel, Steffen Mueller, Josefine Stoll, Heiner Baur, Frank Mayer
BACKGROUND: Back pain patients (BPP) show delayed muscle onset, increased co-contractions, and variability as response to quasi-static sudden trunk loading in comparison to healthy controls (H). However, it is unclear whether these results can validly be transferred to suddenly applied walking perturbations, an automated but more functional and complex movement pattern. There is an evident need to develop research-based strategies for the rehabilitation of back pain. Therefore, the investigation of differences in trunk stability between H and BPP in functional movements is of primary interest in order to define suitable intervention regimes...
2017: PloS One
https://www.readbyqxmd.com/read/28317905/rigid-high-temperature-heat-shrinkable-polyimide-tubes-with-functionality-as-reducer-couplings
#16
Deyan Kong, Xinli Xiao
Flexible and semi-rigid heat-shrinkable tubes (HSTs) have been used in thousands of applications, and here rigid high temperature HSTs are reported for the first time. These rigid HSTs are prepared with shape memory polyimides possessing glass transition temperatures (Tgs) from 182 to 295 °C, and the relationships between Tg and their molecular structures are studied. The polyimide HSTs (PIHSTs) can fix expanded diameters and shrink back to original diameters very well, and the mechanisms of their heat-shrinkage performance are discussed...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317285/changes-in-the-relative-population-size-of-selected-ruminal-bacteria-following-an-induced-episode-of-acidosis-in-beef-heifers-receiving-viable-and-non-viable-active-dried-yeast
#17
R Mohammed, D Vyas, W Z Yang, K A Beauchemin
AIMS: To characterize the changes in the relative population size (RPS) of select ruminal bacteria and rumen fermentation variables in beef heifers supplemented with a strain of Saccharomyces cerevisiae as viable active dried (ADY) or killed dried (KDY) yeast following an induced episode of ruminal acidosis. METHODS AND RESULTS: Six ruminally-cannulated beef heifers fed a diet consisting of 50% forage and 50% grain (dry matter basis) were used in a replicated 3 × 3 Latin square design with three 28 d periods...
March 20, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28317249/getting-back-to-the-dissecting-room-an-evaluation-of-an-innovative-course-in-musculoskeletal-anatomy-for-uk-based-rheumatology-training
#18
Tim Blake, Debbi Marais, Andrew B Hassell, Kay Stevenson, Zoe Paskins
BACKGROUND: The rheumatologist relies heavily on clinical skills to diagnose diverse conditions, something that is correlated with one's knowledge of clinical anatomy. More recently, rheumatology has offered further career flexibility with opportunities to develop skills such as joint injection and musculoskeletal (MSK) ultrasound, both of which require a sound understanding of anatomy. Currently, there are no formal strategies to support competency-based anatomy learning in rheumatology in the UK...
March 20, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28315366/amygdala-functional-connectivity-is-associated-with-locus-of-control-in-the-context-of-cognitive-aging
#19
Ping Ren, Mia Anthony, Benjamin P Chapman, Kathi Heffner, Feng Lin
Locus of control (LOC) measures the extent to which individuals perceive control over their lives. Those with a more "internal" LOC feel self-sufficient and able to determine important aspects of their own future, while those with a more "external" LOC feel that their lives are governed by events beyond their control. Reduced internal LOC and increased external LOC have been found in cognitive disorders, but the neural substrates of these control perceptions are yet unknown. In the present study, we explored the relationship between amygdala functional connectivity and LOC in 18 amnestic mild cognitive impairment (MCI) and age-, sex-, and education-matched, 22 cognitively healthy controls (HC)...
March 14, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28314524/development-of-the-japanese-version-of-the-psychosocial-assessment-of-candidates-for-transplantation-in-allogeneic-hematopoietic-stem-cell-transplantation
#20
Saki Harashima, Ryo Yoneda, Takeshi Horie, Mami Kayano, Yosei Fujioka, Fumihiko Nakamura, Mineo Kurokawa, Kazuhiro Yoshiuchi
BACKGROUND: The Psychosocial Assessment of Candidates for Transplantation (PACT) is a validated instrument for evaluating psychosocial risk factors in transplant candidates. OBJECTIVES: This study examined reliability and validity of the Japanese version of the PACT (J-PACT). METHODS: PACT is a clinician-rated scale consisting of an initial rating, 8 subscales, and a final rating. J-PACT was developed through a translation and back-translation procedure...
January 19, 2017: Psychosomatics
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