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https://www.readbyqxmd.com/read/28719872/health-related-quality-of-life-in-patients-undergoing-lumbar-total-disc-replacement-a-comparison-with-the-general-population
#1
Clavel Pablo, Gheorghe Ungureanu, Catalá Ignasi, Guillermo Montes, Xavier Málaga, Moisés Ríos
OBJECTIVES: In up to half of the cases, low back pain (LBP) is thought to be related to a degeneration of the lumbar disc. Lumbar total disc replacement (LTDR) emerged as an alternative to fusion, but its use and indications are still subject to debate. The purpose of this paper was to compare Health-related Quality of life (HRQOL) in patients undergoing LTDR for one or two-level degenerative disc disease (DDD) with the paired age and gender general population values and to assess functional disability and residual pain at one year after the surgical procedure...
July 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28717781/spinal-cord-infarction-mimicking-ischemic-heart-disease
#2
Dae Won Lee, Yoon Hee Choi
Spinal cord infarction is a rare condition and is easily misdiagnosed owing to its initial non-specific manifestation. We report a case of a 77-year-old man who presented with chest pain and upper back pain initially, and was misdiagnosed with a myocardial infarction. Four hours after admission, he complained of numbness in his entire left leg below the knee, with rapid deterioration of neurological symptoms. After 9 hours, loss of sensation progressed up to the T4 dermatome, strength of both lower extremities deteriorated to grade 0, and decrease in anal tone and deep tendon reflex was observed...
June 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28717415/chronic-antiepileptic-drug-use-and-functional-network-efficiency-a-functional-magnetic-resonance-imaging-study
#3
Tamar M van Veenendaal, Dominique M IJff, Albert P Aldenkamp, Richard H C Lazeron, Paul A M Hofman, Anton J A de Louw, Walter H Backes, Jacobus F A Jansen
AIM: To increase our insight in the neuronal mechanisms underlying cognitive side-effects of antiepileptic drug (AED) treatment. METHODS: The relation between functional magnetic resonance-acquired brain network measures, AED use, and cognitive function was investigated. Three groups of patients with epilepsy with a different risk profile for developing cognitive side effects were included: A "low risk" category (lamotrigine or levetiracetam, n = 16), an "intermediate risk" category (carbamazepine, oxcarbazepine, phenytoin, or valproate, n = 34) and a "high risk" category (topiramate, n = 5)...
June 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28716620/distinct-physical-function-profiles-in-older-adults-receiving-cancer-chemotherapy
#4
Christine Miaskowski, Melisa L Wong, Bruce A Cooper, Judy Mastick, Steven M Paul, Katherine Possin, Michael Steinman, Janine Cataldo, Laura B Dunn, Christine Ritchie
CONTEXT: While physical function is an important patient outcome, little is known about changes in physical function in older adults receiving chemotherapy (CTX). OBJECTIVES: Identify subgroups of older patients based on changes in their level of physical function; determine which demographic and clinical characteristics were associated with subgroup membership; and determine if these subgroups differed on quality of life (QOL) outcomes. METHODS: Latent profile analysis (LPA) was used to identify groups of older oncology patients (n=363) with distinct physical function profiles...
July 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28716590/lumbar-muscle-inflammation-alters-spinally-mediated-locomotor-recovery-induced-by-training-in-a-mouse-model-of-complete-spinal-cord-injury
#5
Renaud Jeffrey-Gauthier, Mathieu Piché, Hugues Leblond
Locomotor networks after spinal cord injury (SCI) are shaped by training-activated proprioceptive and cutaneous inputs. Nociception from injured tissues may alter these changes but has largely been overlooked. The objective of the present study was to ascertain whether lumbar muscle inflammation hinders locomotion recovery in a mouse model of complete SCI. Lower limb kinematics during treadmill training was assessed before and after complete SCI at T8 (2, 7, 14, 21 and 28 days post-injury). Locomotor recovery was compared in 4 groups of CD1 mice: control spinal mice; spinal mice with daily locomotor training; spinal mice with lumbar muscle inflammation (Complete Freund's Adjuvant (CFA) injection); and spinal mice with locomotor training and CFA...
July 14, 2017: Neuroscience
https://www.readbyqxmd.com/read/28716466/chronic-low-back-pain-patients-walk-with-locally-altered-spinal-kinematics
#6
Guillaume Christe, François Kade, Brigitte M Jolles, Julien Favre
Various studies have reported alterations of spinal kinematics in patients with chronic low back pain (CLBP) during gait. However, while recent findings stressed the importance of multi-segment analysis, most of prior gait studies modelled the lumbar spine as one segment, when it was not the entire trunk that was considered as a single segment. Therefore, there is a need for comprehensive multi-segment research that could improve our understanding of CLBP pathomechanism and thus possibly contribute to better care for CLBP...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28716043/evolution-in-the-surgical-management-of-gastric-cancer-is-extended-lymph-node-dissection-back-in-vogue-in-the-usa
#7
REVIEW
Tianxiang Chen, Dongsheng Yan, Zhiqiang Zheng, Jiayi Yang, Xiang Da Eric Dong
BACKGROUND: Gastric cancer remains a formidable treatment challenge. For decades, treatment consisted mostly of surgical intervention for this deadly disease. With improvements in the multi-disciplinary management of solid organ malignancies, the approach to this disease is being stepwise refined. MAIN BODY: One of the prevalent controversies in the surgical management of gastric cancer rests on the need for adequate harvesting of lymph nodes. For decades, lymph node dissection is regarded as a staging technique useful in only upstaging the disease...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28712715/split-vmat-technique-to-control-the-expiratory-breath-hold-time-in-liver-stereotactic-body-radiation-therapy
#8
Yen Hwa Lin, Shuichi Ozawa, Hideharu Miura, Katsunori Yogo, Takeo Nakashima, Kentaro Miki, Shintaro Tsuda, Yusuke Ochi, Daisuke Kawahara, Tomoki Kimura, Akito Saito, Yasushi Nagata
PURPOSE: In this study, we demonstrate the feasibility of using split-arcs in volumetric modulated arc therapy (VMAT), tailored for expiratory breath-hold in stereotactic body radiation therapy (SBRT) for liver tumors. We compare it with three-dimensional conformal radiation therapy (3D-CRT) and continuous-VMAT, for ten randomly selected hepatocellular carcinoma cases. METHODS: Four coplanar and four non-coplanar beams were used for the 3D-CRT plans. A pair of partial arcs, chosen using a back-and-forth rotating motion, were used for the continuous-VMAT plans...
July 13, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28712701/impact-of-advanced-modeled-iterative-reconstruction-on-interreader-agreement-in-coronary-artery-measurements
#9
Tobias Gassenmaier, Isabel Distelmaier, Andreas M Weng, Thorsten A Bley, Thorsten Klink
OBJECTIVES: To evaluate the influence of advanced modeled iterative reconstruction (ADMIRE) on coronary artery computed tomography angiography (cCTA) measurements in comparison to filtered back projection (FBP). MATERIAL AND METHODS: Phantom scans and coronary CTA studies of 27 patients were acquired with a third generation dual-source CT scanner. Images were reconstructed using FBP and ADMIRE. Phantom measurements were used as reference standard. In patient studies, representative axial slices of each coronary artery segment without (n=308) and with coronary plaques (n=40) were assessed in identical positions for comparison of FBP and ADMIRE reconstructions...
July 1, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28712541/mechanical-demands-on-the-lower-back-in-patients-with-non-chronic-low-back-pain-during-a-symmetric-lowering-and-lifting-task
#10
Iman Shojaei, Elizabeth G Salt, Quenten Hooker, Babak Bazrgari
There is limited information in the literature related to the lower back loading in patients with LBP, particularly those with non-chronic LBP. Toward addressing such a research gap, a case-control study was conducted to explore the differences in lower back mechanical loads between a group of females (n=19) with non-chronic, non-specific LBP and a group of asymptomatic females (n=19). The differences in lower back mechanical loads were determined when participants completed one symmetric lowering and lifting of a 4...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28712342/anterior-cerebral-artery-territory-infarction-related-resolution-of-chronic-lower-back-pain
#11
Christopher M Filley, Haley Burke, C Alan Anderson
No abstract text is available yet for this article.
July 17, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28712043/effects-of-fibre-digestibility-and-level-of-roughage-on-performance-and-rumen-fermentation-of-finishing-beef-cattle
#12
Dannylo Oliveira Sousa, Bruno de Sousa Mesquita, Alexandre Vaz Pires, Miguel Henrique de Almeida Santana, Luis Felipe Prada Silva
The objective was to evaluate effects of neutral detergent fibre (NDF) digestibility and level of fresh sugarcane on intake, body fatness, carcass characteristics, and rumen kinetics and fermentation of beef cattle. Forty-eight Nellore young bulls were used in a complete randomized block design with a 2 × 2 factorial arrangement of treatments. Eight rumen-cannulated Nellore steers were used in a replicated 4 × 4 Latin square design. Two sugarcane genotypes divergent for stalk NDF digestibility (NDFD) were used...
July 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28711120/from-efficacy-to-global-impact-lessons-learned-about-what-not-to-do-in-translating-our-research-to-reach
#13
Carolyn B Becker
Although members of the Association for Behavioral and Cognitive Therapies have made significant strides toward the collective goals outlined in our mission statement, we routinely acknowledge that our ability to develop empirically supported treatments exceeds our success in improving dissemination and implementation of said interventions. Further, as noted by Kazdin and Blase (2011), even if we succeeded in having every clinician worldwide administer our best treatments with excellent competency, we still would be unsuccessful in markedly impacting the worldwide burden of mental illness because most treatments require intensive labor by expensive providers...
September 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28709881/can-primary-care-for-back-and-or-neck-pain-in-the-netherlands-benefit-from-stratification-for-risk-groups-according-to-the-start-back-tool-classification
#14
Jasper D Bier, Janneke J W Sandee-Geurts, Raymond W J G Ostelo, Bart W Koes, Arianne P Verhagen
OBJECTIVE: To evaluate whether current Dutch primary-care clinicians offer tailored treatment to patients with lower-back pain (LBP) or neck pain (NP) according to their risk stratification, based on the Keele STarT (Subgroup Targeted Treatment) Back-Screening Tool (SBT). DESIGN: Prospective cohort study with 3 month follow-up SETTING: Primary care PARTICIPANTS: General practitioners (GPs) and physiotherapists (PTs) included patients with non-specific LBP and/or NP...
July 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28709831/clinical-impact-of-joabpeq-mental-health-scores-in-patients-with-low-back-pain-analysis-using-the-neuropathic-pain-screening-tool-paindetect
#15
Akihiko Hiyama, Hiroyuki Katoh, Daisuke Sakai, Masahiro Tanaka, Masato Sato, Masahiko Watanabe
BACKGROUND: In patients with low back pain (LBP) who combine psychosocial factors with clinical findings of pain, there is a possibility that the psychosocial factors modify the pain. In the current study, we investigated the relationship between the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) mental health score and the characteristics of LBP. METHODS: Of 650 patients with LBP, 319 were excluded, leaving 331 patients included in this study...
July 11, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28709386/health-complaints-in-late-adolescence-frequency-factor-structure-and-the-association-with-socio-economic-status
#16
Solbjørg Makalani Myrtveit Sæther, Børge Sivertsen, Siren Haugland, Tormod Bøe, Mari Hysing
AIMS: Little is known about social disparities in health in late adolescence. Among boys and girls aged 17-19, we aimed to (1) describe frequency of health complaints, (2) investigate the factor structure of health complaints and (3) examine the association between health complaints and socio-economic status (SES). METHODS: Data from the large population-based youth@hordaland survey ( n=10,253) were used. Health complaints were assessed by five items from the Health Behaviour in School-Aged Children Symptoms Checklist, SES by parental education and perceived family economy...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28708140/wideband-tunable-opto-electronic-oscillator-based-on-frequency-translation
#17
Zeev Tamir, Asher Meltzer, Moshe Horowitz
We demonstrate a new method to obtain a widely tunable low phase-noise opto-electronic oscillator (OEO), based on translating the OEO signal into a lower intermediate frequency (IF) signal. The OEO signal is downconverted to IF by using a local oscillator (LO) signal, filtered by a high-Q filter; its frequency is then upconverted back into the high OEO frequency. The combination of a narrowband filter at a fixed central frequency with a tunable LO forms a tunable high-Q bandpass filter (BPF) that can be used to change the OEO frequency over a broad frequency region...
July 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28707222/considering-the-inferior-surface-area-of-lower-lumbar-vertebrae-determining-weight-transmission-pattern-at-the-lumbosacral-junction
#18
Uchenna Kenneth Ezemagu, Chike P Anibeze, Chinedu F Akpuaka
The biomechanical function of the lumbosacral junction (LSJ) is obscure, but its medical significance is not, as it is the most common site of low back pain. In this study, we analyzed the difference between the mean values of the surface areas of the inferior body and total inferior facet areas of the fourth and fifth lumbar vertebrae. We aimed to define the function of the LSJ during weight transmission and clarify its mechanical significance. Vertebral columns of 45 adult male human cadavers from five anatomy departments in Nigeria were cut at the L3-L4 intervertebral disc and macerated...
July 13, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28706535/which-factors-are-important-for-successful-sentinel-node-navigation-surgery-in-gastric-cancer-patients-analysis-from-the-senorita-prospective-multicenter-feasibility-quality-control-trial
#19
Ji Yeong An, Jae Seok Min, Young Joon Lee, Sang Ho Jeong, Hoon Hur, Sang Uk Han, Woo Jin Hyung, Gyu Seok Cho, Gui Ae Jeong, Oh Jeong, Young Kyu Park, Mi Ran Jung, Ji Yeon Park, Young Woo Kim, Hong Man Yoon, Bang Wool Eom, Keun Won Ryu
BACKGROUND: We investigated the results of quality control study prior to phase III trial of sentinel lymph node navigation surgery (SNNS). METHODS: Data were reviewed from 108 patients enrolled in the feasibility study of laparoscopic sentinel basin dissection (SBD) in gastric cancer. Seven steps contain tracer injection at submucosa (step 1) and at four sites (step 2) by intraoperative esophagogastroduodenoscopy (EGD), leakage of tracer (step 3), injection within 3 minutes (step 4), identification of at least one sentinel basin (SB) (step 5), evaluation of sentinel basin nodes (SBNs) by frozen biopsy (step 6), and identification of at least five SBNs at back table and frozen sections (step 7)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28706229/quantitative-interactome-of-a-membrane-bcl-2-network-identifies-a-hierarchy-of-complexes-for-apoptosis-regulation
#20
Stephanie Bleicken, Annika Hantusch, Kushal Kumar Das, Tancred Frickey, Ana J Garcia-Saez
The Bcl-2 proteins form a complex interaction network that controls mitochondrial permeabilization and apoptosis. The relative importance of different Bcl-2 complexes and their spatio-temporal regulation is debated. Using fluorescence cross-correlation spectroscopy to quantify the interactions within a minimal Bcl-2 network, comprised by cBid, Bax, and Bcl-xL, we show that membrane insertion drastically alters the pattern of Bcl-2 complexes, and that the C-terminal helix of Bcl-xL determines its binding preferences...
July 13, 2017: Nature Communications
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