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https://www.readbyqxmd.com/read/28329322/utilization-and-in-hospital-complications-of-cardiac-resynchronization-therapy-trends-in-the-united-states-from-2003-to-2013
#1
Seyed Mohammadreza Hosseini, Kasra Moazzami, Guy Rozen, Jeena Vaid, Ahmed Saleh, E Kevin Heist, Mark Vangel, Jeremy N Ruskin
Aims: Cardiac resynchronization therapy (CRT) device implantation has been shown to reduce morbidity and mortality in selected patients with heart failure. We sought to investigate the utilization and in-hospital complications of cardiac resynchronization therapy defibrillator (CRT-D) and pacemaker (CRT-P) implantations in the United States from 2003 to 2013. Methods and results: Patients receiving CRT-D or CRT-P were identified in the National Inpatient Sample database (NIS), using the International Classification of Diseases-Ninth Revision-Clinical Modification procedure codes...
March 13, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28294364/predictors-and-long-term-outcome-of-super-responders-to-cardiac-resynchronization-therapy
#2
Abdul Ghani, Peter Paul H M Delnoy, Ahmet Adiyaman, Jan Paul Ottervanger, Anand R Ramdat Misier, Jaap Jan J Smit, Arif Elvan
BACKGROUND: The level of improvement in left ventricular ejection fraction (LVEF) in super-responders to cardiac resynchronization therapy (CRT) is exceptional. However, the long-term prognosis remains unknown in a large population. HYPOTHESIS: Whether super-responders haven good long-term outcomes. METHODS: We registered 347 patients with primary CRT-D indication. Super-response was defined by LVEF >50% at follow-up echocardiogram. Best-subset regression analysis identified predictors of super-response...
March 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28292754/cardiac-resynchronization-therapy-reduces-ventricular-arrhythmias-in-primary-but-not-secondary-prophylactic-implantable-cardioverter-defibrillator-patients-insight-from-the-resynchronization-in-ambulatory-heart-failure-trial
#3
John L Sapp, Ratika Parkash, George A Wells, Elizabeth Yetisir, Martin J Gardner, Jeffrey S Healey, Bernard Thibault, Laurence D Sterns, David Birnie, Pablo B Nery, Soori Sivakumaran, Vidal Essebag, Paul Dorian, Anthony S L Tang
BACKGROUND: The RAFT (Resynchronization in Ambulatory Heart Failure Trial) demonstrated that cardiac resynchronization therapy (CRT) reduced both mortality and heart failure hospitalizations in patients with functional class II or III heart failure and widened QRS. We examined the influence of CRT on ventricular arrhythmias in patients with primary versus secondary prophylaxis defibrillator indications. METHODS AND RESULTS: All ventricular arrhythmias among RAFT study participants were downloaded and adjudicated by 2 blinded reviewers with an overreader for disagreements and committee review for remaining discrepancies...
March 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28267958/comparison-of-multivariate-risk-estimation-models-to-predict-prognosis-in-patients-with-implantable-cardioverter-defibrillators-with-or-without-cardiac-resynchronization-therapy
#4
Salima Akoudad, Lara Dabiri Abkenari, Beat A Schaer, Christian Sticherling, Wayne C Levy, Luc Jordaens, Dominic A M J Theuns
Several multivariate risk score models were developed to predict prognosis of patients with heart failure (HF). We compared 3 models with regard to prediction of mortality in patients with HF who received an implantable defibrillator (ICD) or a cardiac resynchronization therapy defibrillator (CRT-D), as primary prevention of sudden death. The study cohort consisted of 823 patients (ICD = 410; CRT-D = 413). The evaluated models were the Seattle Heart Failure Model (SHFM), the Multicenter Automatic Defibrillator Implantation Trial II (MADIT II) score, and an adjusted Charlson Comorbidity Index (aCCI)...
February 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28254126/economic-value-and-cost-effectiveness-of%C3%A2-cardiac-resynchronization-therapy-among-patients-with-mild-heart-failure-projections-from-the-reverse-long-term-follow-up
#5
Michael R Gold, Amie Padhiar, Stuart Mealing, Manpreet K Sidhu, Stelios I Tsintzos, William T Abraham
OBJECTIVES: This study investigated the cost effectiveness of early cardiac resynchronization therapy (CRT) implantation among patients with mild heart failure (HF). The differential cost effectiveness between CRT using a defibrillator (CRT-Ds) and CRT using a pacemaker (CRT-P) was also assessed. BACKGROUND: Cardiac resynchronization has been shown to be cost effective in New York Heart Association (NYHA) functional classes III/IV but is less studied in class II HF...
March 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28251724/temporal-trends-over-a-decade-of-defibrillator-therapy-for-primary-prevention-in-community-practice
#6
Serge Boveda, Kumar Narayanan, Sophie Jacob, Rui Providencia, Frankie Beganton, Vincent Algalarrondo, Pascal Defaye, Marie-Cécile Perier, Nicolas Sadoul, Olivier Piot, Didier Klug, Daniel Gras, Laurent Fauchier, Pierre Bordachar, Dominique Babuty, Jean-Claude Deharo, Christophe Leclercq, Eloi Marijon
BACKGROUND: Technology and clinical practice surrounding the use of the primary prevention implantable cardioverter defibrillator (ICD) are in a state of constant evolution. The purpose of the study was to test the hypothesis of significant temporal trends in characteristics and outcomes over a decade of ICD therapy. METHODS: Between 2002-2012, 5,539 consecutive patients (age 62.5±11 years, 84.9% male), with ischemic or non-ischemic cardiomyopathy, implanted with a primary prevention ICD from 12 centers in France were included...
March 2, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28242289/epicardial-crt-d-in-a-pacing-dependant-patient-without-transvenous-options
#7
Hariharan Sugumar, George Matalanis, Liam Toner, David O'Donnell
Implantable cardioverter-defibrillator (ICD) and cardiac resynchronisation therapy (CRT) is generally limited to transvenous techniques especially in pacing-dependant patients. We describe a novel case in which an epicardial CRT-D system was successfully implanted with a two-year follow-up in a pacing-dependant patient.
February 11, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28225475/stretching-exercises-improve-vascular-endothelial-dysfunction-through-attenuation-of-oxidative-stress-in-chronic-heart-failure-patients-with-an-implantable-cardioverter-defibrillator
#8
Michitaka Kato, Takashi Masuda, Michio Ogano, Kazuki Hotta, Hisato Takagi, Shinya Tanaka, Yumi Kamada, Ayako Akiyama, Daisuke Kamekawa, Ryosuke Shimizu, Minoru Tabata, Jun Tanabe, Takuya Umemoto
PURPOSE: Endurance training improves oxidative stress and vascular endothelial dysfunction in patients with chronic heart failure (CHF). However, patients with CHF and an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) often avoid endurance training for fear of ICD shock. Recent studies have reported that stretching exercises enhance antioxidant activity and improve vascular responses. Therefore, we aimed to assess the effects of 4 weeks of stretching exercises on oxidative stress and vascular endothelial function in patients with CHF with an ICD or CRT-D...
March 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28220942/crt-induced-ventricular-tachyarrhythmia-what-s-the-mechanism
#9
Sanoj Chacko, Enes Gul, Chris Simpson, Adrian Baranchuk
A 56-year-old woman with non-ischemic dilated cardiomyopathy and severe left ventricular systolic dysfunction received cardiac resynchronization defibrillator therapy (CRT-D; St Jude Medical Quadra Assura, CA, USA), for primary prevention and management of heart failure. This article is protected by copyright. All rights reserved.
February 21, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28204917/-ecg-score-to-predict-icd-therapies-in-patients-with-nonischemic-cardiomyopathy-and-primary-prophylactic-crt-d
#10
Martin Grett, Martin Christ, Jan-Peter Röing Gen Nölke, Hans-Joachim Trappe
BACKGROUND AND PROBLEM: Recently published results of the DANISH study raise concerns, if primary prophylactic ICD implantations in patients with nonischemic cardiomyopathy (NICM) and severe reduced left ventricular ejection fraction (LVEF) should be performed without further risk stratification. There was no significant difference in the overall mortality of patients with or without ICD and CRT defibrillator (CRT-D) or CRT pacemaker (CRT-P), respectively. Clinical risk scores to identify patients with ischemic cardiomyopathy (ICM) who benefit most from an ICD have been recommended...
February 15, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28188000/effectiveness-of-a-management-program-for-outpatient-clinic-or-remote-titration-of-beta-blockers-in-crt-patients-the-restore-study
#11
Antonio D'Onofrio, Pietro Palmisano, Antonio Rapacciuolo, Ernesto Ammendola, Leonardo Calò, Antonio Ruocco, Valter Bianchi, Fabio Maresca, Giuseppe Del Giorno, Annamaria Martino, Ciro Mauro, Monica Campari, Sergio Valsecchi, Michele Accogli
BACKGROUND: Many patients fail to receive β-blockers before cardiac resynchronization therapy defibrillator (CRT-D) implantation, or receive them at a suboptimal dose, and require optimization after implantation. We assessed the effectiveness of a structured program for β-blocker titration in CRT-D patients followed up by means of conventional in-clinic visits or remote monitoring. METHODS AND RESULTS: 130 patients undergoing CRT implantation and treated according to the standard practice of the centers were included as a control group...
February 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28176442/impact-of-remote-monitoring-on-long-term-prognosis-in-heart-failure-patients-in-a-real-world-cohort-results-from-all-comers-commit-hf-trial
#12
Anna Kurek, Mateusz Tajstra, Elzbieta Gadula-Gacek, Piotr Buchta, Michal Skrzypek, Lukasz Pyka, Michal Wasiak, Malgorzata Swietlinska, Michal Hawranek, Lech Polonski, Mariusz Gasior, Jedrzej Kosiuk
BACKGROUND: Randomized controlled trials demonstrate that remote monitoring (RM) of implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy devices (CRT-D) may improve quality of care and prognosis in heart failure (HF) patients. However, the impact of RM on long-term mortality in a real-world cohort is still not well examined. METHODS AND RESULTS: This study was designed as a matched cohort study based on the COMMIT-HF trial - a single-center, ongoing prospective observational registry (NCT02536443)...
February 8, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28173045/increasing-age-does-not-affect-time-to-appropriate-therapy-in-primary-prevention-icd-crt-d-a-competing-risks-analysis
#13
David G Wilson, Hrvojka Marija Zeljko, Georgios Leventopoulos, Ahmed Nauman, George E H Sylvester, Arthur Yue, Paul R Roberts, Glyn Thomas, Edward R Duncan, Paul J Roderick, John M Morgan
No abstract text is available yet for this article.
February 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28158423/sex-specific-precision-medicine-targeting-crt-d-and-other-cardiovascular-interventions-to-those-most-likely-to-benefit
#14
Viviany R Taqueti, C Noel Bairey Merz
No abstract text is available yet for this article.
February 3, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28156008/a-device-histogram-based-simple-predictor-of-mortality-risk-in-icd-and-crt-d-patients-the-heart-rate-score
#15
Bruce L Wilkoff, Mark Richards, Arjun Sharma, Nicholas Wold, Paul Jones, David Perschbacher, Brian Olshansky
BACKGROUND: We hypothesized survival in cardioverter defibrillator (ICD) and cardiac resynchronization defibrillator (CRT-D) patients is predicted by baseline Heart rate Score. METHODS: Heart rate Score is determined from the atrial paced and sensed histogram of a DDD ICD or CRT-D, and defined as percent of beats in the histogram in the tallest 10 beat/minute range bin. It was calculated at initial remote monitoring for patients enrolled in LATITUDE® without persistent atrial fibrillation (AF), and with pulse generators implanted 2006-2011...
February 3, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28150288/the-impact-of-remote-monitoring-of-implanted-cardioverter-defibrillator-icd-and-cardiac-resynchronization-therapy-device-crt-d-patients-on-healthcare-costs-in-the-silesian-population-3-year-follow-up
#16
Piotr Buchta, Mateusz Tajstra, Anna Kurek, Michał Skrzypek, Małgorzata Świetlińska, Elżbieta Gadula-Gacek, Michał Wasiak, Łukasz Pyka, Mariusz Gąsior
BACKGROUND: The population of patients with implanted cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy devices (CRT-Ds) is constantly growing. The use of remote-monitoring (RM) techniques in this group can significantly improve clinical outcomes, but there are limited data about the impact of RM on healthcare costs from a payer's perspective. AIM: The aim of the study was to assess the impact on costs for the healthcare system of RM in patients with ICDs or CRT-Ds...
February 2, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28134226/-the-evaluation-of-the-ventricular-arrhythmias-and-interventions-of-cardiac-implantable-electronic-devices-in-patients-with-dilated-cardiomyopathy-for-primary-prevention-of-sudden-cardiac-death-in-ambulatory-and-telemetric-follow-up
#17
Jacek Lelakowski, Anna Rydlewska, Maria Lelakowska, Joanna Pudło, Justyna Piekarz
Telemetric follow-up (RM) after cardiac devices implantation is not inferior to classic follow-up and enables earlier clinical complications detection. AIM: The aim of the study was to evaluation of the ventricular arrhythmias and interventions of ICD/CRTD in ambulatory and telemetric follow-up in patients with dilated cardiomyopathy. MATERIALS AND METHODS: Group A (CRT-D+ICD) - retrospective, patients followed-up in outpatient clinic - was consisted with 273 patients (mean age 65±11 years, 230M)...
January 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28131706/electrical-treatment-of-atrial-arrhythmias-in-heart-failure-patients-implanted-with-a-dual-defibrillator-crt-device-results-from-the-trade-hf-study
#18
Giovanni Luca Botto, Luigi Padeletti, Gregorio Covino, Paolo Pieragnoli, Mattia Liccardo, Barbara Mariconti, Stefano Favale, Giulio Molon, Paolo De Filippo, Leonardo Bolognese, Maurizio Landolina, Giovanni Raciti, Giuseppe Boriani
BACKGROUND: Ventricular and atrial arrhythmias commonly occur in heart failure patients and are a significant source of symptoms, morbidity and mortality. Some specific generators referred to as dual defibrillators, Dual CRT-Ds, have the ability to treat atrial and ventricular arrhythmias. TRADE-HF is a prospective two-arm randomized study aimed at assessing the benefits of complete automatic management of atrial arrhythmias in patients implanted with a dual CRT-D. METHODS: Primary objective of the TRADE-HF study was to document reduction of unplanned hospital admission for cardiac reasons or death for cardiovascular causes or progression to permanent AF, by comparing fully-automatic device driven therapy for atrial tachycardia or fibrillation (AT/AF) to an in-hospital approach for treatment of symptomatic AT/AF...
January 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28122073/use-of-cardiac-resynchronization-therapy-among-eligible-patients-receiving-an-implantable-cardioverter-defibrillator-insights-from-the-national-cardiovascular-data-registry-implantable-cardioverter-defibrillator-registry
#19
Lucas N Marzec, Pamela N Peterson, Haikun Bao, Jeptha P Curtis, Frederick A Masoudi, Paul D Varosy, Steven M Bradley
Importance: Cardiac resynchronization therapy (CRT) reduces the risk for mortality and heart failure-related events in select patients. Little is known about the use of CRT in combination with an implantable cardioverter defibrillator (ICD) in patients who are eligible for this therapy in clinical practice. Objective: To (1) identify patient, clinician, and hospital characteristics associated with CRT defibrillator (CRT-D) use and (2) determine the extent of hospital-level variation in the use of CRT-D among guideline-eligible patients undergoing ICD placement...
January 25, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28104669/sex-specific-outcomes-with-addition-of-defibrillation-to-resynchronisation-therapy-in-patients-with-heart-failure
#20
Sérgio Barra, Rui Providência, Rudolf Duehmke, Serge Boveda, Eloi Marijon, Christian Reitan, Rasmus Borgquist, Didier Klug, Pascal Defaye, Nicolas Sadoul, Jean-Claude Deharo, Iannish Sadien, Kiran Patel, Khang-Li Looi, David Begley, Anthony W Chow, Jean-Yves Le Heuzey, Sharad Agarwal
OBJECTIVE: Among primary prevention patients with heart failure receiving cardiac resynchronisation therapy (CRT), the impact of additional implantable cardioverter defibrillator (ICD) treatment on outcomes and its interaction with sex remains uncertain. We aim to assess whether the addition of the ICD functionality to CRT devices offers a more pronounced survival benefit in men compared with women, as previous research has suggested. METHODS: Observational multicentre cohort study of 5307 consecutive patients with ischaemic or non-ischaemic dilated cardiomyopathy and no history of sustained ventricular arrhythmias having CRT implantation with (cardiac resynchronisation therapy defibrillator (CRT-D), n=4037) or without (cardiac resynchronisation therapy pacemaker (CRT-P), n=1270) defibrillator functionality...
January 19, 2017: Heart: Official Journal of the British Cardiac Society
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