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https://www.readbyqxmd.com/read/28078492/first-report-of-bla-ctx-m-15-type-esbl-producing-klebsiella-pneumoniae-in-wild-migratory-birds-in-pakistan
#1
Shahbaz Raza, Mashkoor Mohsin, Waqas Ahmed Madni, Fatima Sarwar, Muhammad Saqib, Bilal Aslam
We investigated wild migratory birds faecal swabs for extended-spectrum β-lactamases-producing Klebsiella pneumoniae (ESBL-K. pneumoniae) from wetland habitats in Pakistan. ESBL-K. pneumoniae were analysed for MDR phenotype, ESBL genotype and genetic diversity. A total of 13 (8.6%) ESBL-K. pneumoniae were recovered. Of these, 8 (61%) isolates were MDR. DNA sequencing confirmed bla CTX-M-15 as the dominant ESBL genotype. BOX-PCR fingerprints showed most of the isolates are unrelated. This study is the first to report the wildlife contamination of CTX-M-15-producing K...
January 11, 2017: EcoHealth
https://www.readbyqxmd.com/read/28077864/knowledge-and-perceptions-of-polio-and-polio-immunization-in-polio-high-risk-areas-of-pakistan
#2
Muhammad Atif Habib, Sajid Bashir Soofi, Noshad Ali, Imtiaz Hussain, Farhana Tabassum, Zamir Suhag, Saeed Anwar, Imran Ahmed, Zulfiqar Ahmed Bhutta
Pakistan and Afghanistan remain the only countries where polio is endemic, and Pakistan reports the most cases in the world. Although the rate is lower than in previous years, the situation remains alarming. We conducted a mixed methods study in high-risk areas of Pakistan to identify knowledge, attitudes, and practices of target populations about polio vaccine and its eradication, and to estimate coverage of routine immunization and oral polio vaccine. We surveyed 10,685 households in Karachi, 2522 in Pishin, and 2005 in Bajaur...
January 11, 2017: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28077163/the-efficacy-of-varenicline-in-achieving-abstinence-among-waterpipe-tobacco-smokers-study-protocol-for-a-randomized-controlled-trial
#3
Raana Zahid, Omara Dogar, Sonia Mansoor, Amina Khan, Mona Kanaan, Mohammed Jawad, Jasjit S Ahluwalia, Kamran Siddiqi
BACKGROUND: Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking tobacco in Pakistan. A range of behavioral and pharmacological therapies are available to support people in quitting cigarette smoking; however, little evidence exists for the efficacy of these therapies in achieving abstinence among waterpipe tobacco smokers. The objective of this study is to assess the efficacy of varenicline when added to behavioral support for waterpipe tobacco smoking cessation, by measuring biochemically validated continuous abstinence in waterpipe tobacco smokers...
January 11, 2017: Trials
https://www.readbyqxmd.com/read/28076428/does-measles-vaccination-reduce-the-risk-of-acute-respiratory-infection-ari-and-diarrhea-in-children-a-multi-country-study
#4
Rahul Bawankule, Abhishek Singh, Kaushalendra Kumar, Sadanand Shetye
BACKGROUND: Pneumonia and diarrhea occur either as complications or secondary infections in measles affected children. So, the integrated Global Action Plan for Pneumonia and Diarrhea (GAPPD) by WHO and UNICEF includes measles vaccination as preventive measure in children. The objective of the study is to examine the effect of measles vaccination on Acute Respiratory Infection (ARI) and diarrhea in children in the Democratic Republic of Congo, Ethiopia, India, Nigeria, and Pakistan. METHODS: We analyzed data from the most recent rounds of Demographic and Health Surveys (DHS) in the selected countries...
2017: PloS One
https://www.readbyqxmd.com/read/28071616/presenting-features-treatment-patterns-and-outcomes-of-patients-with-breast-cancer-in-pakistan-experience-at-a-university-hospital
#5
S Kumar, A J Shaikh, Y A Rashid, N Masood, Atv Mohammed, U Z Malik, G Haider, N Niamutullah, S Khan
BACKGROUND: Breast cancer is the most common cancer in Pakistani women. We report the presenting features, treatment patterns and survival of breast cancer from a University Hospital in Southern Pakistan and compare the data with international population based studies. MATERIALS AND METHODS: Medical records of patients diagnosed to have breast cancer between January 1999 and November 2008 were reviewed retrospectively. RESULTS: A total of 845 patients were identified...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28070467/social-support-and-resilience-among-patients-with-burn-injury-in-lahore-pakistan
#6
Ahmed Waqas, Sadiq Naveed, Mariam M Bhuiyan, Jawad Usman, Ahmed Inam-Ul-Haq, Sara S Cheema
INTRODUCTION: Social support and ego resiliency play a great role in maintaining the physical and mental health of patients with burn injuries. The present study has been designed to compare ego resiliency levels and the degree of social support in patients with a burn injury and their healthy counterparts. METHODS: This study was conducted in two teaching hospitals in Lahore, Pakistan from May 2015 to July 2015. A total of 80 burn patients presenting in outpatient departments of general surgery, plastic surgery, and burn centers of these hospitals were surveyed conveniently, and for comparison, 80 patients presenting in outpatient departments with minor ailments, for routine checkups or follow-ups were recruited...
November 8, 2016: Curēus
https://www.readbyqxmd.com/read/28069955/ambivalent-stereotypes-link-to-peace-conflict-and-inequality-across-38-nations
#7
Federica Durante, Susan T Fiske, Michele J Gelfand, Franca Crippa, Chiara Suttora, Amelia Stillwell, Frank Asbrock, Zeynep Aycan, Hege H Bye, Rickard Carlsson, Fredrik Björklund, Munqith Dagher, Armando Geller, Christian Albrekt Larsen, Abdel-Hamid Abdel Latif, Tuuli Anna Mähönen, Inga Jasinskaja-Lahti, Ali Teymoori
A cross-national study, 49 samples in 38 nations (n = 4,344), investigates whether national peace and conflict reflect ambivalent warmth and competence stereotypes: High-conflict societies (Pakistan) may need clearcut, unambivalent group images distinguishing friends from foes. Highly peaceful countries (Denmark) also may need less ambivalence because most groups occupy the shared national identity, with only a few outcasts. Finally, nations with intermediate conflict (United States) may need ambivalence to justify more complex intergroup-system stability...
January 9, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28068110/maternal-scaffolding-in-a-disadvantaged-global-context-the-influence-of-working-memory-and-cognitive-capacities
#8
Jelena Obradović, Ximena A Portilla, Nicole Tirado-Strayer, Saima Siyal, Muneera A Rasheed, Aisha K Yousafzai
The current study focuses on maternal cognitive capacities as determinants of parenting in a highly disadvantaged global context, where children's experiences at home are often the 1st and only opportunity for learning and intellectual growth. In a large sample of 1,291 biological mothers of preschool-aged children in rural Pakistan, we examined the unique association of maternal working memory skills (independent of related cognitive capacities) with cognitively stimulating parenting behaviors. Path analysis revealed that directly assessed working memory, short-term memory, and verbal intelligence independently predicted greater levels of observed maternal scaffolding behaviors...
January 9, 2017: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/28067995/antibody-prevalence-and-risk-factors-for-toxoplasma-gondii-infection-in-women-from-multan-pakistan
#9
M M Nazir, M Akhtar, A Maqbool, A Waheed, M A Sajid, M A Ali, M Oneeb, M A Alam, A N Ahmad, N Nazir, S Fatima, D S Lindsay
Toxoplasma gondii infections are prevalent in humans and warm-blooded animals. Maternal infections during pregnancy may have devastating consequences for transplacentally infected neonates. This study was conducted to examine the seroprevalence of antibodies to T. gondii in pregnant women of childbearing age and determine risk factors associated with pregnancy history, pet ownership, social and cultural factors at Nishtar Hospital, Multan. Samples were collected from 403 women and examined using a commercially available enzyme-linked immunosorbent assay (ELISA)...
January 9, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28067622/a-homozygous-fitm2-mutation-causes-a-deafness-dystonia-syndrome-with-motor-regression-and-signs-of-ichthyosis-and-sensory-neuropathy
#10
Celia Zazo Seco, Anna Castells-Nobau, Seol-Hee Joo, Margit Schraders, Jia Nee Foo, Monique van der Voet, S Sendhil Velan, Bonnie Nijhof, Jaap Oostrik, Erik de Vrieze, Radoslaw Katana, Atika Mansoor, Martijn Huynen, Radek Szklarczyk, Martin Oti, Lisbeth Tranebjærg, Erwin van Wijk, Jolanda M Scheffer-de Gooyert, Saadat Siddique, Jonathan Baets, Peter de Jonghe, Syed Ali Raza Kazmi, Suresh Anand Sadananthan, Bart P van de Warrenburg, Chiea Chuen Khor, Martin C Göpfert, Raheel Qamar, Annette Schenck, Hannie Kremer, Saima Siddiqi
A consanguineous family from Pakistan was ascertained with a novel deafness-dystonia syndrome with motor regression, ichthyosis-like features and signs of sensory neuropathy. By applying a combined strategy of linkage analysis and whole-exome sequencing in the presented family, a homozygous nonsense mutation, c.4G>T (p.Glu2*), in FITM2 was identified. FITM2 and its paralog FITM1 constitute an evolutionary conserved protein family involved in partitioning of triglycerides into cellular lipid droplets. Despite the role of FITM2 in neutral lipid storage and metabolism, no indications for lipodystrophy were observed in the affected individuals...
December 15, 2016: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28065969/survellience-system-for-child-abuse-bridging-the-gap-between-actual-and-hidden-cases
#11
Maryam Pyar Ali Lakhdir, Yasmin Parpio, Salima Farooq
The dynamics of child abuse have been recognised as a global emerging social issue which is highly associated with child humiliation. The Government of Pakistan has taken many initiatives for addressing issues regarding child abuse and neglect and has designed laws to protect children against exploitation, abuse and violence; however, most of them are not enforced at all or poorly implemented due to lack of proper definition of child abuse and related terms, and different ways of reporting child abuse cases...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065965/lessons-from-a-seven-year-experience-of-paediatric-hiv-in-pakistan-a-single-centre-experience
#12
Ejaz Ahmed Khan
OBJECTIVE: To describe demographic, clinical and immunologic features of children with human immunodeficiency virus. METHODS: This descriptive study was conducted at the Shifa International Hospital, Islamabad, Pakistan, from 2005 to 2011, and comprised children with human immunodeficiency virus and acquired immune deficiency syndrome. Patients with detailed physical examination and appropriate investigations and those eligible for therapy were included. SPSS 21 was used for data analysis...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065964/future-priorities-of-interns-in-public-and-private-tertiary-care-hospitals-of-a-mega-city-in-a-developing-country
#13
Shiraz Shaikh, Munnaza Obaid, Sobia Memon, Kulsoom Shaikh, Hafsa Siddiqui
OBJECTIVE: To determine the future priorities of young medical doctors in tertiary care hospitals in a major urban centre. METHODS: This multi-centre cross-sectional study was conducted at four tertiary care hospitals of Karachi, Pakistan, from January to June 2015, and comprised medical interns. A questionnaire-based survey was conducted. The participants were inquired about their demographics, preferred places and hospitals for training in the future and reason for their choices...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065962/compliance-of-surgical-hand-washing-before-surgery-role-of-remote-video-surveillance
#14
Ambreen Khan, Sidrah Nausheen
OBJECTIVE: To evaluate and increase the compliance of surgical hand scrubbing with periodic feedback. METHODS: This study was conducted at the Aga Khan Hospital for Women and Children, Karachi, Pakistan, from April to July 2014. A remote video auditing system consisting of human auditors was used for visualising surgical hand wash compliance of the surgical team. The equipment, which used motion sensor, was installed in the scrub area wall, visualising the scrub sink only...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065961/the-effect-of-deep-cross-friction-massage-on-spasticity-of-children-with-cerebral-palsy-a-double-blind-randomised-controlled-trial
#15
Faisal Rasool, Aamir Raoof Memon, Mubin Mustafa Kiyani, Abdul Ghafoor Sajjad
OBJECTIVE: To find out the effect of deep cross-friction massage on spasticity in children with cerebral palsy. METHODS: This double-blind randomised controlled trial was conducted at the National Institute of Rehabilitation Medicine, Islamabad, Pakistan, from January to July 2013, and comprised paediatric patients with spastic diplegic cerebral palsy. The participants were equally divided into control and treatment groups by a staff member unaware of the treatment (allocation ratio 1:1)...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065959/clinical-profile-of-patients-with-biopsy-proven-lupus-nephritis-at-a-tertiary-care-hospital-from-northern-pakistan-1995-to-2012
#16
Akhtar Ali, Anjum Mehmood, Muhammad Usman Ali
OBJECTIVE: TTo highlight the clinical spectrum of biopsy-proven lupus nephritis by analysing any variations in its histological subtypes across gender, varying age groups, serum creatinine levels and anti-double stranded deoxyribonucleic acid levels. METHODS: This retrospective, observational study was conducted at the Lady Reading Hospital in collaboration with the Fauji Foundation Hospital, Peshawar, Pakistan, and comprised patient records of biopsy-proven lupus nephritis from 1995 to 2012...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065958/role-of-clinical-skill-centre-in-undergraduate-medical-education-initial-experience-at-rehman-medical-college-peshawar
#17
Zainab Shafiq, Tariq Saeed Mufti, Iftikhar Qayum
OBJECTIVE: To assess the performance of students on clinical skill factors and to measure the satisfaction level of students related to the training. METHODS: The descriptive study was conducted at Rehman Medical College, Peshawar, Pakistan, from August 1 to September 15, 2013, and comprised all third-year medical students who had undergone clinical skill training. Their performance was evaluated through end-of-module objective structured clinical examination. Students' feedback measuring satisfaction on a five-point Likert scale was obtained on a designed validated tool...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065955/analysis-of-pattern-of-mortality-in-medicine-and-allied-departments-at-a-tertiary-care-hospital-in-islamabad-a-losing-battle-against-sepsis
#18
Saad Azim, Sidra Zahoor, Jamal Janjua, Azer Majeed, Syed Waqar Hussain
OBJECTIVE: To identify the pattern of mortality in medical wards of a tertiary care hospital. METHODS: This retrospective study was conducted at the Khan Research Laboratories Hospital, Islamabad, Pakistan, and comprised medical records of people who died during hospital stay between December 2013 and November 2014.SPSS 11 was used for data analysis. RESULTS: Of the 3,228 admissions, 105(3.25%) patients expired. Of them, 41(39.04%) were men with a mean age of 55±13...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065953/self-evaluation-of-ethical-review-committees-functioning-at-foundation-university-medical-college-fumc-through-structured-constitution-practice-outcome-cpo-assessment-model
#19
Sadia Ahsin, Gul E Naghma Saeed
OBJECTIVE: To assess the operational efficiency of the ethical review committee of a medical college. METHODS: This study was conducted at the Foundation University Medical College, Islamabad, Pakistan, from 2012 to 2014. On the basis of literature review, methods for assessment of various features of ethical review committee were studied. A constitution-practice-outcome measurement model for evaluation of ethical review committee assessment process was developed...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065952/harassment-of-working-women-in-the-public-health-sector-of-abbottabad-in-socio-legal-perspective
#20
Musarrat Jabeen, Zeeshan Muhammad Naeem, Muhammad Umar, Muhammad Arfat Yameen, Saira Azhar
OBJECTIVE: To investigate the efficacy and impact of Protection Against Harassment of Women at Workplace Act 2010 in the public health sector in its socio-legal perspective. METHODS: This cross-sectional study was conducted from July to December 2014 in Abbottabad, Pakistan, and comprised subjects selected from 53 basic health units managed by the government. SPSS 20 was used for statistical analysis. RESULTS: Of the 450 questionnaires, 430(96...
January 2017: JPMA. the Journal of the Pakistan Medical Association
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