Giacomo Bertolini, Laura Belli, Stefania Mazza, Pietro Tito Ugolotti, Iacopo Tadonio, Patrizia Ceccarelli, Sandra Rossi, Salvatore Ippolito
Antiplatelet therapy is mandatory for prevention of thrombotic events in patients with a recent history of acute coronary syndromes and/or percutaneous coronary interventions. However, if an urgent surgery is required during antiplatelet therapy, a compromise between the ischemic/thrombotic and hemorrhagic risk has to be reached. Different bridging schemes are reported in the literature, but there is no clear consensus on the optimal treatment strategy in terms of efficacy and safety. Although some indications about the perioperative management of antiplatelet therapy regarding specific surgical specializations are available, balancing the thrombotic and hemorrhagic risk on an individual basis, no evidence referring to neurosurgical or neuro-oncologic procedures is reported...
April 15, 2024: Journal of Neurological Surgery. Part A, Central European Neurosurgery