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https://www.readbyqxmd.com/read/28719923/-breaking-bad-news-to-cancer-patients-content-communication-preferences-and-psychological-distress
#1
Claudia Gebhardt, Claudia Gorba, Karin Oechsle, Sigrun Vehling, Uwe Koch, Anja Mehnert
Objectives Breaking bad news can be a very distressing situation for both patients and physicians. Physician communication behavior should therefore match patients' communication preferences. The aim of this study was to characterize the content of bad news from the patients' perspective. Patients' preferences for communication of bad news as well as the fit to communication behavior displayed by physicians were also investigated. Finally, consequences of a mismatch between patients' preferences and physician communication were investigated in relation to psychological distress in patients...
July 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28688661/use-of-axillary-lymph-node-dissection-alnd-in-patients-with-micrometastatic-breast-cancer
#2
Madison Collins, Cristina O'Donoghue, Weihong Sun, Jun-Min Zhou, Zhenjun Ma, Christine Laronga, Marie Catherine Lee
BACKGROUND: Sentinel lymph node (SLN) biopsy is the current prognostic tool for clinically node-negative breast cancer patients. If the SLN reveals macrometastasis, axillary lymph node dissection (ALND) is recommended. However, the use of ALND in patients with micrometastasis is debated. The objective of this study was to assess the utilization of ALND in the treatment of micrometastatic breast cancer. METHODS: An IRB approved, retrospective study of a pooled dataset of breast cancer patients with micrometastatic disease on SLN biopsy was performed...
July 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28687585/nccn-news
#3
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28687581/acute-myeloid-leukemia-version-3-2017-nccn-clinical-practice-guidelines-in-oncology
#4
Margaret R O'Donnell, Martin S Tallman, Camille N Abboud, Jessica K Altman, Frederick R Appelbaum, Daniel A Arber, Vijaya Bhatt, Dale Bixby, William Blum, Steven E Coutre, Marcos De Lima, Amir T Fathi, Melanie Fiorella, James M Foran, Steven D Gore, Aric C Hall, Patricia Kropf, Jeffrey Lancet, Lori J Maness, Guido Marcucci, Michael G Martin, Joseph O Moore, Rebecca Olin, Deniz Peker, Daniel A Pollyea, Keith Pratz, Farhad Ravandi, Paul J Shami, Richard M Stone, Stephen A Strickland, Eunice S Wang, Matthew Wieduwilt, Kristina Gregory, Ndiya Ogba
Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths due to leukemias in the United States. This portion of the NCCN Guidelines for AML focuses on management and provides recommendations on the workup, diagnostic evaluation, and treatment options for younger (age <60 years) and older (age ≥60 years) adult patients.
July 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28687576/nccn-guidelines-insights-antiemesis-version-2-2017
#5
Michael J Berger, David S Ettinger, Jonathan Aston, Sally Barbour, Jason Bergsbaken, Philip J Bierman, Debra Brandt, Dawn E Dolan, Georgiana Ellis, Eun Jeong Kim, Steve Kirkegaard, Dwight D Kloth, Ruth Lagman, Dean Lim, Charles Loprinzi, Cynthia X Ma, Victoria Maurer, Laura Boehnke Michaud, Lisle M Nabell, Kim Noonan, Eric Roeland, Hope S Rugo, Lee S Schwartzberg, Bridget Scullion, John Timoney, Barbara Todaro, Susan G Urba, Dorothy A Shead, Miranda Hughes
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Antiemesis address all aspects of management for chemotherapy-induced nausea and vomiting. These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines for Antiemesis, specifically those regarding carboplatin, granisetron, and olanzapine.
July 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28687575/value-tools-for-patients-in-cancer-care
#6
Katy Winckworth-Prejsnar, Lisa Korin Lentz, Elizabeth A Nardi, Sandhya Pruthi, C Lyn Fitzgerald, Robert W Carlson
In order to empower patients as partners in their healthcare decisions, there is an identified need for value tools that provide enough information to help them make decisions regarding their cancer care journey. NCCN convened a multistakeholder working group to identify the gaps and needs of current value tools and develop a set of findings and recommendations for the evolution of value tools for patients. The findings and recommendations of the working group were then presented at the Value Tools for Patients in Cancer Care Patient Advocacy Summit in December 2016, and multistakeholder roundtable panel discussions explored these findings and recommendations along with additional items...
July 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28686891/comparison-of-aerosol-and-cloud-condensation-nuclei-between-wet-and-dry-seasons-in-guangzhou-southern-china
#7
Junyan Duan, Jun Tao, Yunfei Wu, Tiantao Cheng, Renjian Zhang, Yanyu Wang, Hailin Zhu, Xin Xie, Yuehui Liu, Xiang Li, Lingdong Kong, Mei Li, Qianshan He
Cloud condensation nuclei (CCN), condensation nuclei (CN) and aerosol chemical composition were measured simultaneously at an urban site of Guangzhou from July to August 2015 and in January 2016, and the seasonal variations of aerosol activated fractions (NCCN/NCN) as well as their relevant influence factors were further studied accordingly. NCN is generally higher in winter (dry season), whereas NCCN and NCCN/NCN are mostly higher in summer (wet season) instead. In particular, NCCN and NCCN/NCN are much lower at smaller supersaturation levels (SS<0...
July 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28682915/long-term-outcome-of-thyroid-lobectomy-for-unilateral-multifocal-papillary-carcinoma
#8
Hui Huang, Shaoyan Liu, Zhengang Xu, Song Ni, Zongmin Zhang, Xiaolei Wang
The National Comprehensive Cancer Network (NCCN) guidelines recommend completion thyroidectomy for patients with multifocal papillary thyroid carcinoma (PTC) diagnosed by paraffin pathology after lobectomy. However, studies for the influence of surgical range on prognosis of unilateral multifocal carcinoma are scarce. We analyzed the clinicopathological characteristics and long-term outcomes of patients with unilateral multifocal PTC to identify risk factors for recurrence and disease-related death.The clinical and pathological data of 123 cases with multifocal lesions in the unilateral thyroid lobe were retrospectively collected, including sex, age, stage, surgical range, histopathology characteristics, and follow-up data...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28681157/refining-the-role-of-lymph-node-biopsy-in-survival-for-patients-with-nasopharyngeal-carcinoma-population-based-study-from-the-surveillance-epidemiology-and-end-results-registry
#9
Jia-Wei Lv, Guan-Qun Zhou, Yu-Pei Chen, Ling-Long Tang, Yan-Ping Mao, Lei Chen, Wen-Fei Li, Ai-Hua Lin, Jun Ma, Ying Sun
BACKGROUND: The updated version of the National Comprehensive Cancer Network (NCCN) guidelines revised pretreatment workup for nasopharyngeal carcinoma (NPC) into "biopsy of the primary site or neck." Despite provision of important diagnostic information, concerns regarding tumor cell dissemination limit the application of lymph node biopsy. This study aimed to investigate whether biopsy of the neck is associated with impaired survival in NPC. METHODS: A propensity score-matched, population-based cohort identified from the Surveillance, Epidemiology, and End Results database was used to compare overall survival (OS) and disease-specific survival (DSS) of patients who underwent pretreatment cervical lymph node biopsy without subsequent neck dissection or removal of node compared with patients who did not undergo node biopsy...
July 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28678809/the-number-of-cd34-cd38-cd117-hla-dr-cd13-cd33-cells-indicates-post-chemotherapy-hematopoietic-recovery-in-patients-with-acute-myeloid-leukemia
#10
Runxia Gu, Hui Wei, Ying Wang, Dong Lin, Bingcheng Liu, Chunlin Zhou, Kaiqi Liu, Benfa Gong, Shuning Wei, Guangji Zhang, Xiaoyuan Gong, Yuntao Liu, Yan Li, Xingli Zhao, Shaowei Qiu, Huijun Wang, Min Wang, Yingchang Mi, Jianxiang Wang
Hematopoietic recovery is considered to be associated with the number of multipotent hematopoietic stem cells in the bone marrow, as observed in functional assays involving stem cell transplantation. However, there is little evidence related to hematopoietic recovery in non-transplantation settings, which is accomplished by endogenous hematopoietic cells. A recent study suggested that progenitors are the main contributors during this steady-state hematopoiesis, which differs from exogenous transplantation. We hypothesized that endogenous progenitor support post-chemotherapy hematopoietic recovery...
2017: PloS One
https://www.readbyqxmd.com/read/28678667/relation-between-narrow-networks-and-providers-of-cancer-care
#11
Laura Yasaitis, Justin E Bekelman, Daniel Polsky
Purpose Health insurers offer plans covering a narrow subset of providers in an attempt to lower premiums and compete for consumers. However, narrow networks may limit access to high-quality providers, particularly those caring for patients with cancer. Methods We examined provider networks offered on the 2014 individual health insurance exchanges, assessing oncologist supply and network participation in areas that do and do not contain one of 69 National Cancer Institute (NCI)-Designated Cancer Centers. We characterized a network's inclusion of oncologists affiliated with NCI-Designated Cancer Centers relative to oncologists excluded from the network within the same region and assessed the relationship between this relative inclusion and each network's breadth...
July 5, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28669010/a-cross-sectional-analysis-from-a-single-institution-s-experience-of-psychosocial-distress-and-health-related-quality-of-life-in-the-primary-brain-tumor-population
#12
Dina M Randazzo, Frances McSherry, James E Herndon, Mary Lou Affronti, Eric S Lipp, Charlene Flahiff, Elizabeth Miller, Sarah Woodring, Maria Freeman, Patrick Healy, Janet Minchew, Susan Boulton, Annick Desjardins, Gordana Vlahovic, Henry S Friedman, Stephen Keir, Katherine B Peters
Primary brain tumor patients experience high levels of distress. The purpose of this cross-sectional, retrospective study is to evaluate the level and different sources of psychosocial distress and how these pertain to health-related quality of life (HRQoL). The Primary and Recurrent Glioma registry at Duke's The Preston Robert Tisch Brain Tumor Center was queried retrospectively for demographic and clinical information on patients seen between December 2013 and February 2014. Data also included the National Comprehensive Cancer Network's Distress Thermometer (NCCN-DT), Functional Assessment of Cancer Therapy-Brain Cancer (FACT-Br), and Functional Assessment of Chronic Illness Therapy- Fatigue (FACIT-F)...
July 1, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28662426/first-results-from-light-scattering-enhancement-factor-over-central-indian-himalayas-during-gvax-campaign
#13
U C Dumka, D G Kaskaoutis, Ram Sagar, Jianmin Chen, Narendra Singh, Suresh Tiwari
The present work examines the influence of relative humidity (RH), physical and optical aerosol properties on the light-scattering enhancement factor [f(RH=85%)] over central Indian Himalayas during the Ganges Valley Aerosol Experiment (GVAX). The aerosol hygroscopic properties were measured by means of DoE/ARM (US Department of Energy, Atmospheric Radiation Measurement) mobile facility focusing on periods with the regular instrumental operation (November-December 2011). The measured optical properties include aerosol light-scattering (σsp) and absorption (σap) coefficients and the intensive parameters i...
June 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28655095/-efficacy-and-prognostic-analysis-of-98-cases-of-relapsed-refractory-diffuse-large-b-cell-lymphoma-treated-with-second-line-regimens
#14
M C Zhang, Y Qian, J Hao, Z Y Liu, W L Zhao, L Wang
Objective: To evaluate the efficacy and prognostic factors of second-line regimens for patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). Methods: A retrospective analysis was performed in 98 patients with relapsed/refractory DLBCL who were treated with salvage regimens in Rui Jin Hospital from July 2004 to June 2016. Overall response rate (ORR) was evaluated after all treatment finished. Overall survival (OS) was analyzed by Kaplan-Meier method and multivariate by Cox proportional hazards models...
June 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/28653453/ahns-series-do-you-know-your-guidelines-principles-of-treatment-for-glottic-cancer-a-review-of-the-national-comprehensive-cancer-network-guidelines
#15
Jessica Yesensky, Nishant Agrawal, Semirra Bayan, Elizabeth Blair, Louis Portugal, Jason Chan, David Goldenberg, Zhen Gooi
This article is a continuation of the "Do You Know Your Guidelines" series, an initiative of the American Head and Neck Society's Education Committee to increase awareness of current best practices pertaining to head and neck cancer. The National Comprehensive Cancer Network (NCCN) guidelines for primary and adjuvant treatment of cancer of the glottic larynx are reviewed here in a systematic fashion according to stage.
June 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28645632/adjuvant-chemotherapy-guided-by-molecular-profiling-and-improved-outcomes-in-early-stage-non-small-cell-lung-cancer
#16
Gavitt A Woodard, Sue X Wang, Johannes R Kratz, Clara T Zoon-Besselink, Chun-Yuan Chiang, Matthew A Gubens, Thierry M Jahan, Collin M Blakely, Kirk D Jones, Michael J Mann, David M Jablons
INTRODUCTION: Many early stage non-small-cell lung cancer (NSCLC) patients who are not considered candidates for adjuvant treatment according to current guidelines do harbor occult metastasis, and have disease recurrence despite complete resection. Although National Comprehensive Cancer Network (NCCN) guidelines suggest clinicopathologic characteristics to identify high-risk patients for adjuvant intervention, molecular profiling more accurately predicts 5-year survival. Early evidence of clinical benefit from application of this molecular-based management strategy, however, has not been reported...
May 31, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28645325/performance-characteristics-of-prostate-specific-antigen-density-and-biopsy-core-details-to-predict-oncological-outcome-in-patients-with-intermediate-to-high-risk-prostate-cancer-underwent-robot-assisted-radical-prostatectomy
#17
Masahiro Yashi, Akinori Nukui, Yuumi Tokura, Kohei Takei, Issei Suzuki, Kazumasa Sakamoto, Hideo Yuki, Tsunehito Kambara, Hironori Betsunoh, Hideyuki Abe, Yoshitatsu Fukabori, Yoshimasa Nakazato, Yasushi Kaji, Takao Kamai
BACKGROUND: Many urologic surgeons refer to biopsy core details for decision making in cases of localized prostate cancer (PCa) to determine whether an extended resection and/or lymph node dissection should be performed. Furthermore, recent reports emphasize the predictive value of prostate-specific antigen density (PSAD) for further risk stratification, not only for low-risk PCa, but also for intermediate- and high-risk PCa. This study focused on these parameters and compared respective predictive impact on oncologic outcomes in Japanese PCa patients...
June 23, 2017: BMC Urology
https://www.readbyqxmd.com/read/28612456/day-14-bone-marrow-examination-in-the-management-of-acute-myeloid-leukemia
#18
REVIEW
Christopher M Terry, Rory M Shallis, Elihu Estey, Seah H Lim
The National Comprehensive Cancer Network (NCCN) recommends that a repeat bone marrow evaluation is carried out seven to ten days following completion of induction therapy so that if a patient's day 14 bone marrow shows residual blast cell counts of >10%, the patient would proceed early to a second cycle of induction therapy. Although blast cell counts of <5% on day 14 bone marrow is sensitive in predicting remission on day 28, various studies have found that day 14 bone marrow is highly nonspecific because a large proportion of patients with blast cell counts of >5% on day 14 bone marrow would still attain a complete remission of the disease without any further chemotherapy...
June 13, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28606707/disparities-in-compliance-with-the-oncotype-dx-breast-cancer-test-in-the-united-states-a-national-cancer-data-base-assessment
#19
Zachary Kozick, Ammar Hashmi, James Dove, Marie Hunsinger, Tania Arora, Jeffrey Wild, Mohsen Shabahang, Joseph Blansfield
BACKGROUND: Oncotype DX (ODX) is a multi-gene tumor assay for breast cancer patients. Our objective is to assess whether eligible ODX patients received the test and whether recommendations were followed based on respective risk. METHODS: We retrospectively analyzed testing in patients deemed eligible for ODX using the National Cancer Data Base. RESULTS: A total of 158,235 patients met ODX eligibility criteria. Sixty-four percent of eligible patients did not receive the test...
June 9, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28597183/discrepancies-between-nccn-and-esmo-guidelines-in-the-management-of-anal-cancer-a-qualitative-review
#20
REVIEW
Natalie Johnson, Gianluca Pellino, Constantinos Simillis, Shengyang Qiu, Stella Nikolaou, Daniel L Baird, Shahnawaz Rasheed, Paris P Tekkis, Christos Kontovounisios
There is an ever-growing need, with the ongoing developments in research and the progress towards patient centered care, to delineate standardized protocols of management of anal cancer. However, guidelines from different societies show some degree of disagreement. This is a systematic review of the literature to identify similarities and discrepancies between the guidelines for the management of anal cancer drafted by the European Society for Medical Oncology (ESMO) and by the National Comprehensive Cancer Network (NCCN)...
June 8, 2017: Updates in Surgery
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