keyword
MENU ▼
Read by QxMD icon Read
search

Bmi and RA

keyword
https://www.readbyqxmd.com/read/28273936/discovery-of-circulating-proteins-associated-to-knee-radiographic-osteoarthritis
#1
Lucía Lourido, Burcu Ayoglu, Juan Fernández-Tajes, Natividad Oreiro, Frauke Henjes, Cecilia Hellström, Jochen M Schwenk, Cristina Ruiz-Romero, Peter Nilsson, Francisco J Blanco
Currently there are no sufficiently sensitive biomarkers able to reflect changes in joint remodelling during osteoarthritis (OA). In this work, we took an affinity proteomic approach to profile serum samples for proteins that could serve as indicators for the diagnosis of radiographic knee OA. Antibody suspension bead arrays were applied to analyze serum samples from patients with OA (n = 273), control subjects (n = 76) and patients with rheumatoid arthritis (RA, n = 244). For verification, a focused bead array was built and applied to an independent set of serum samples from patients with OA (n = 188), control individuals (n = 83) and RA (n = 168) patients...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28259162/joint-specific-assessment-of-swelling-and-power-doppler-in-obese-rheumatoid-arthritis-patients
#2
Erin M Bauer, Ami Ben-Artzi, Erin L Duffy, David A Elashoff, Sitaram S Vangala, John Fitzgerald, Veena K Ranganath
BACKGROUND: Clinical swollen joint examination of the obese rheumatoid arthritis (RA) patient can be difficult. Musculoskeletal Ultrasound (MSUS) has higher sensitivity than physical examination for swollen joints (SJ). The purpose of this study was to determine the joint-specific association between power Doppler (PDUS) and clinical SJ in RA across body mass index (BMI) categories. METHODS: Cross-sectional clinical and laboratory data were collected on 43 RA patients...
March 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28258473/sarcopenia-in-rheumatoid-arthritis-prevalence-influence-of-disease-activity-and-associated-factors
#3
Ange Ngeuleu, F Allali, L Medrare, A Madhi, H Rkain, N Hajjaj-Hassouni
Evaluate the prevalence of sarcopenia on patients with rheumatoid arthritis (RA), the influence of sarcopenia on disease activity and factors associated with sarcopenia. One hundred and twenty-three patients aged over 18 years with RA based on the 1987 ACR/EULAR classification criteria were enrolled. We performed a whole body DXA scan using a dual-energy X-ray absorptiometry (DXA) scanner lunar prodigy to measure fat mass, lean mass, and bone mass in the whole body and body parts. According to the anthropometric equation by Baumgartner et al...
March 3, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28257782/natural-history-predictors-and-management-of-uretero-enteric-strictures-after-robot-assisted-radical-cystectomy
#4
Youssef E Ahmed, Ahmed A Hussein, Paul R May, Basim Ahmad, Taimoor Ali, Prasanna Kumar, Khurshid A Guru
PURPOSE: Uretero-enteric strictures (UES) represent the most common complication requiring reoperation after radical cystectomy. Our objective was to investigate the prevalence, outcomes, predictors and management of UES. METHODS: Retrospective review of our quality assurance RARC database and identified patients who developed UES. Data was reviewed for demographics, perioperative outcomes and UES characteristics. Kaplan Meier method was used to compute time to UES and multivariable stepwise regression to evaluate predictors of UES...
February 28, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28255666/influence-of-systemic-bone-mineral-density-on-atlantoaxial-subluxation-in-patients-with-rheumatoid-arthritis
#5
M H Han, J I Ryu, C H Kim, J M Kim, J H Cheong, K H Bak, H J Chun
Osteopenia and osteoporosis were independent predictive factors for higher atlantoaxial subluxation occurrence in patients with lower body mass index. Our findings suggest that patients with rheumatoid arthritis with osteopenia or osteoporosis, particularly those with lower body mass index (BMI), should be screened regularly to determine the status of their cervical spines. INTRODUCTION: Cervical spine involvement in rheumatoid arthritis (RA) patients may cause serious adverse effects on quality of life and overall health...
March 2, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28229811/patient-phenotypes-in-fibromyalgia-comorbid-with-systemic-sclerosis-or-rheumatoid-arthritis-influence-of-diagnostic-and-screening-tests-screening-with-the-first-questionnaire-diagnosis-with-the-acr1990-and-revised-acr-2010-criteria
#6
Serge Perrot, Mariana Peixoto, Philippe Dieudé, Eric Hachulla, Jerome Avouac, Sebastien Ottaviani, Yannick Allanore
OBJECTIVES: Fibromyalgia (FM) may occur with rheumatoid arthritis (RA) and systemic sclerosis (SSc), and debate remains about its diagnosis. We aimed to use three FM tools (a screening tool (FiRST), diagnostic criteria (ACR 1990 and revised 2010), to compare FM prevalence between RA and SSc patients, to describe the phenotypes of patients with comorbid FM, and to analyze links between FM and secondary Sjögren's syndrome (SS). METHODS: Consecutive adult patients with confirmed RA or SSc from four university hospitals were tested with the three FM tools...
February 8, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28217867/effects-of-25-hydroxyvitamin-d-and-vitamin-d-binding-protein-on-bone-mineral-density-and-disease-activity-in-malaysian-patients-with-rheumatoid-arthritis
#7
Tze Hao Wong, Esha Das Gupta, Ammu K Radhakrishnan, Suk Chyn Gun, Gandhi Chembalingam, Swan Sim Yeap
AIM: Vitamin D3 [25(OH)D] has been shown to be important in bone health and can influence rheumatoid arthritis (RA) disease activity. Vitamin D-binding protein (VDBP) levels vary with race and may modulate 'bioavailable' levels of 25(OH)D. The aim of this study was to explore the relationships between 25(OH)D, VDBP and clinical factors on bone mineral density (BMD) in a group of multi-ethnic Malaysian RA patients and healthy controls. METHODS: A cross-sectional study of 77 female RA patients and 29 controls was performed...
February 20, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28217415/muscle-activation-patterns-during-suspension-training-exercises
#8
Sean Harris, Elise Ruffin, Wayne Brewer, Alexis Ortiz
BACKGROUND: Suspension training (ST) has been utilized over exercises performed on a stable surface to train multiple muscle groups simultaneously to increase muscle activation and joint stability. HYPOTHESIS/PURPOSE: The purpose of this study was to determine whether ST augments muscle activation compared to similar exercises performed on a stable surface. STUDY DESIGN: Cross-sectional study. METHODS: Twenty-five healthy adults (male: 16; women: 9; BMI: 23...
February 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28187765/does-a-lack-of-physical-activity-explain-the-rheumatoid-arthritis-lipid-profile
#9
Hiba AbouAssi, Margery A Connelly, Lori A Bateman, K Noelle Tune, Janet L Huebner, Virginia B Kraus, Deborah A Winegar, James D Otvos, William E Kraus, Kim M Huffman
BACKGROUND: In rheumatoid arthritis (RA), cardiovascular risk is associated with paradoxical reductions in total cholesterol, low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C). Concentrations of small LDL (LDL-P) and HDL (HDL-P) particles are also reduced with increased inflammation and disease activity in RA patients. Here we sought to identify which measure(s) of inflammation, disease activity and cardiometabolic risk contribute most to the RA-associated lipoprotein profile...
February 10, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28150104/assessment-of-six-cardiovascular-risk-calculators-in-mexican-mestizo-patients-with-rheumatoid-arthritis-according-to-the-eular-2015-2016-recommendations-for-cardiovascular-risk-management
#10
Dionicio A Galarza-Delgado, Jose R Azpiri-Lopez, Iris J Colunga-Pedraza, Jesus A Cardenas-de la Garza, Raymundo Vera-Pineda, Griselda Serna-Peña, Rosa I Arvizu-Rivera, Adrian Martinez-Moreno, Martin Wah-Suarez, Mario A Garza Elizondo
Variability of the 10-year cardiovascular (CV) risk predicted by the Framingham Risk Score (FRS) using lipids, FRS using body mass index (BMI), Reynolds Risk Score (RRS), QRISK2, Extended Risk Score-Rheumatoid Arthritis (ERS-RA), and algorithm developed by the American College of Cardiology and the American Heart Association in 2013 (ACC/AHA 2013) according to the European League Against Rheumatism (EULAR) 2015/2016 update of its evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis (RA) has not been evaluated in Mexican mestizo patients...
February 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28116570/frailty-and-reduced-physical-function-go-hand-in-hand-in-adults-with-rheumatoid-arthritis-a-us-observational-cohort-study
#11
James S Andrews, Laura Trupin, Edward H Yelin, Catherine L Hough, Kenneth E Covinsky, Patricia P Katz
Reduced physical function and health-related quality of life are common in rheumatoid arthritis (RA), and further studies are needed that examine novel determinates of reduced physical function in RA. This study examines whether frailty, a state of increased vulnerability to stressors, is associated with differences in self-reported physical function among adults with RA. Adults from a longitudinal RA cohort (n = 124) participated in the study. Using an established definition of frailty, individuals with three or more of the following physical deficits were classified as frail: (1) body mass index ≤18...
January 23, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28114971/molecular-alterations-in-skeletal-muscle-in-rheumatoid-arthritis-are-related-to-disease-activity-physical-inactivity-and-disability
#12
Kim M Huffman, Ryan Jessee, Brian Andonian, Brittany N Davis, Rachel Narowski, Janet L Huebner, Virginia B Kraus, Julie McCracken, Brian F Gilmore, K Noelle Tune, Milton Campbell, Timothy R Koves, Deborah M Muoio, Monica J Hubal, William E Kraus
BACKGROUND: To identify molecular alterations in skeletal muscle in rheumatoid arthritis (RA) that may contribute to ongoing disability in RA. METHODS: Persons with seropositive or erosive RA (n = 51) and control subjects matched for age, gender, race, body mass index (BMI), and physical activity (n = 51) underwent assessment of disease activity, disability, pain, physical activity and thigh muscle biopsies. Muscle tissue was used for measurement of pro-inflammatory markers, transcriptomics, and comprehensive profiling of metabolic intermediates...
January 23, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28073685/obesity-is-the-main-determinant-of-insulin-resistance-more-than-the-circulating-pro-inflammatory-cytokines-levels-in-rheumatoid-arthritis-patients
#13
Jesus Castillo-Hernandez, Martha Imelda Maldonado-Cervantes, Juan Pablo Reyes, Nuria Patiño-Marin, Enrique Maldonado-Cervantes, Claudia Solorzano-Rodriguez, Esperanza de la Cruz Mendoza, Brenda Alvarado-Sanchez
BACKGROUND: Systemic blockade of TNF-α in Rheumatoid arthritis (RA) with insulin resistance (IR) seems to produce more improvement in insulin sensitivity in normal weight patients with RA than in obese patients with RA, suggesting that systemic-inflammation and obesity are independent risk factors for IR in RA patients. OBJECTIVES: To evaluate the insulin resistance in: normal weight patients with RA (RA NW), overweight patients with RA (RA OW), obese RA patients (RA OB), and matched control subjects with normal weight (NW) and obesity (OB); and its association with major cytokines involved in the pathogenesis of the disease...
December 20, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28049882/the-relationship-between-circulating-neutrophil-gelatinase-associated-lipocalin-and-early-alteration-of-metabolic-parameters-is-associated-with-dietary-saturated-fat-intake-in-non-diabetic-korean-women
#14
Ga Yoon Na, So Ra Yoon, Juhyun An, Rimkyo Yeo, Juhyun Song, Mi-Na Jo, Seongho Han, Oh Yoen Kim
Circulating neutrophil gelatinase-associated lipocalin (NGAL) is associated with obesity-related metabolic disorders. This study investigated the relationship between serum NGAL and early alteration of metabolic parameters in non-diabetic Korean women, particularly with respect to saturated fat (SFA) intake. Anthropometric parameters, fasting glycemic status, and levels of lipids, oxidative stress/inflammatory markers, and NGAL were measured in 82 non-diabetic Korean women [Super-healthy group (n=57) with 0 metabolic syndrome risk factor (MetS RF) and MetS-risk group (n=25) with MetS RF≥1]...
December 30, 2016: Endocrine Journal
https://www.readbyqxmd.com/read/28043761/the-effect-of-body-mass-index-on-clinical-response-to-abatacept-as-a-first-line-biologic-for-rheumatoid-arthritis-6-month-results-from-the-2-year-observational-prospective-action-study
#15
Xavier Mariette, Rieke Alten, Hubert G Nüßlein, Mauro Galeazzi, Hanns-Martin Lorenz, Alain Cantagrel, Melanie Chartier, Coralie Poncet, Christiane Rauch, Manuela Le Bars
OBJECTIVE: To assess the impact of baseline body mass index (BMI) on the efficacy and retention of intravenous abatacept at 6 months in biologic-naïve patients with rheumatoid arthritis (RA). METHODS: This was a 6-month analysis of a 2-year, non-interventional, international, prospective study. Baseline characteristics, clinical response and retention rates were compared by BMI subgroup: underweight/normal, overweight and obese (<25, 25 to <30 and ≥30kg/m(2), respectively)...
December 30, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28028684/are-obesity-acpas-and-periodontitis-conditions-that-influence-the-risk-of-developing-rheumatoid-arthritis-in-first-degree-relatives
#16
Sonia Unriza-Puin, Wilson Bautista-Molano, Gloria I Lafaurie, Rafael Valle-Oñate, Philippe Chalem, Lorena Chila-Moreno, Juan Manuel Bello-Gualtero, Consuelo Romero-Sánchez
The aim of this study was to investigate the body mass index (BMI), anti-citrullinated protein antibodies (ACPAs) status and the presence of periodontitis and IgG-1/IgG-2 antibodies against Porphyromonas gingivalis (Pg) in the first-degree relatives (FDRs) of rheumatoid arthritis (RA) patients and compare these variables with a control group of healthy individuals from the general population. In total, 100 FDR individuals and 200 healthy controls matched by age and gender were included. Rheumatologic and periodontal assessment was performed, and the presence of ACPAs and anti-P...
December 28, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27994266/secretory-activity-of-subcutaneous-abdominal-adipose-tissue-in-male-patients-with-rheumatoid-arthritis-and-osteoarthritis-association-with-clinical-and-laboratory-data
#17
Ewa Kontny, Agnieszka Zielińska, Krystyna Księżopolska-Orłowska, Piotr Głuszko
INTRODUCTION: Adipose tissue exerts widespread effects on the metabolism and immune system, but its activity differs between the genders. In the general population low-grade adipose tissue inflammation contributes to development of diseases of affluence. Little is known about the systemic impact of peripheral fat tissue in osteoarthritis (OA) and rheumatoid arthritis (RA), characterized by chronic, low- and high-grade systemic inflammation, respectively. To clarify this we evaluated the secretory activity of subcutaneous abdominal adipose tissue (SAAT) obtained from male patients affected with RA (n = 21) and OA (n = 13), and assessed its association with body mass and composition, demographic, clinical and laboratory data...
2016: Reumatologia
https://www.readbyqxmd.com/read/27981248/absence-of-a-positive-correlation-between-crp-and-leptin-in-rheumatoid-arthritis
#18
Seyed Reza Najafizadeh, Ghasem Farahmand, Ahmad Tahamoli Roudsari, Behnam Heidari, Mehrdad Larry, Arash Aghajani Nargesi, Atieh Pajouhi, Alireza Esteghamati, Manouchehr Nakhjavani
AIMS: Rheumatoid Arthritis (RA) is a model of chronic inflammatory disease. In this study we evaluated the correlation of leptin and CRP in patients with RA and normal controls. MAIN METHODS: A total of 75 patients with RA and 40 healthy adults were recruited in this case-control study. RA patients were categorized into high (DAS-28 > 3.2) and low activity (DAS ≤ 3.2) group according to their DAS-28 score. KEY FINDINGS: Leptin level was significantly correlated with CRP in healthy controls (r = 0...
December 2016: Heliyon
https://www.readbyqxmd.com/read/27966068/body-mass-does-not-impact-the-clinical-response-to-intravenous-abatacept-in-patients-with-rheumatoid-arthritis-analysis-from-the-pan-european-registry-collaboration-for-abatacept-panaba
#19
Florenzo Iannone, Delphine S Courvoisier, Jacques Eric Gottenberg, Maria Victoria Hernandez, Elisabeth Lie, Helena Canhão, Karel Pavelka, Merete Lund Hetland, Carl Turesson, Xavier Mariette, Denis Choquette, Axel Finckh
Some evidences suggest that obesity impairs the effectiveness of TNF inhibitors. We examined the impact of body mass index (BMI) on the clinical effectiveness of abatacept in rheumatoid arthritis (RA) patients. This is a pooled analysis of 10 prospective cohorts of RA patients. All patients with available BMI were included in this study. The primary endpoint was drug retention of abatacept in the different BMI categories. Multivariable Cox regression was used to estimate hazard ratios (HRs) for drug discontinuation...
December 14, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27939764/elevated-bmi-and-antibodies-to-citrullinated-proteins-interact-to-increase-rheumatoid-arthritis-risk-and-shorten-time-to-diagnosis-a-nested-case-control-study-of-women-in-the-nurses-health-studies
#20
Sara K Tedeschi, Jing Cui, Elizabeth V Arkema, William H Robinson, Jeremy Sokolove, Nithya Lingampalli, Jeffrey A Sparks, Elizabeth W Karlson, Karen H Costenbader
OBJECTIVE: Overweight/obesity and anti-citrullinated protein antibodies (ACPA) increase rheumatoid arthritis (RA) risk. We investigated the relationship between body mass index (BMI) and ACPA, tested for an interaction between BMI and ACPA for RA risk, and examined effects of BMI and ACPA on time to RA diagnosis. DESIGN: Within the Nurses' Health Studies, blood samples were collected before diagnosis from medical record-confirmed incident RA cases and matched controls...
September 13, 2016: Seminars in Arthritis and Rheumatism
keyword
keyword
30798
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"