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Dongfeng-Tongji cohort

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https://www.readbyqxmd.com/read/27795732/association-between-parity-and-obesity-patterns-in-a-middle-aged-and-older-chinese-population-a-cross-sectional-analysis-in-the-tongji-dongfeng-cohort-study
#1
Wending Li, Yi Wang, Lijun Shen, Lulu Song, Hui Li, Bingqing Liu, Jing Yuan, Youjie Wang
BACKGROUND: Higher parity has been implicated as a risk factor for obesity of women. The objective of the study was to examine whether parity was associated with general obesity or abdominal obesity, or both, among middle-aged and older Chinese women. METHODS: A total of 12,829 Chinese women (mean age: 64.8 years) with at least one live birth were selected from the Dongfeng-Tongji Cohort Study (phase II). We used body mass index to assess general obesity, and waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and waist circumference (WC) to assess abdominal obesity...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27752898/parity-and-risk-of-ovarian-cysts-cross-sectional-evidence-from-the-dongfeng-tongji-cohort-study
#2
Chrispin Mandiwa, Li-Jun Shen, Yao-Hua Tian, Lu-Lu Song, Gui-Qiang Xu, Si-Yi Yang, Yuan Liang, Jing Yuan, You-Jie Wang
Little is known about the association between parity and the risk of ovarian cysts. The aim of this study was to examine the association between parity and the risk of ovarian cysts among a population of Chinese women. A total of 20 502 women aged 45-86 years from the Dongfeng-Tongji Cohort study completed baseline questionnaires, medical examination and provided baseline blood samples. Participants were categorized into four groups according to parity (one, two, three, and four or more live births). Logistic regression models were used to investigate the association between parity and the risk of ovarian cysts...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27694567/plasma-metabolomics-identified-novel-metabolites-associated-with-risk-of-type-2-diabetes-in-two-prospective-cohorts-of-chinese-adults
#3
Gaokun Qiu, Yan Zheng, Hao Wang, Jie Sun, Hongxia Ma, Yang Xiao, Yizhun Li, Yu Yuan, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Yue Jiang, Xiaomin Zhang, Meian He, Ming Yang, Zhibin Hu, Huiru Tang, Hongbing Shen, Frank B Hu, An Pan, Tangchun Wu
BACKGROUND: Metabolomics studies in Caucasians have identified a number of novel metabolites in association with the risk of type 2 diabetes (T2D). However, few prospective metabolomic studies are available in Chinese populations. In the present study, we sought to identify novel metabolites consistently associated with incident T2D in two independent cohorts of Chinese adults. METHODS: We performed targeted metabolomics (52 metabolites) of fasting plasma samples by liquid chromatography-mass spectrometry in two prospective case-control studies nested within the Dongfeng-Tongji (DFTJ) cohort and Jiangsu Non-communicable Disease (JSNCD) cohort...
September 30, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27665401/dose-response-relationship-between-serum-uric-acid-levels-and-risk-of-incident-coronary-heart-disease-in-the-dongfeng-tongji-cohort
#4
Xuefeng Lai, Liangle Yang, Sébastien Légaré, Francesca Angileri, Xuguang Chen, Qin Fang, Handong Yang, Ce Zhang, Xiulou Li, Xinwen Min, Chengwei Xu, Jing Yuan, Mei-An He, Tangchun Wu, Xiaomin Zhang
BACKGROUND: In prospective studies, relationship of serum uric acid (SUA) with risk of coronary heart disease (CHD) incidence is inconsistent. We evaluated the association of SUA with incident CHD and the potential modifying effect of major CHD risk factors related to SUA among a middle aged and elderly Chinese population. METHODS: We included 16, 063 participants who were free of CHD, stroke, cancer and renal diseases at baseline from Sep. 2008 to June 2010, and were followed until Oct...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27632700/induced-and-spontaneous-abortion-and-risk-of-uterine-fibroids
#5
Lulu Song, Lijun Shen, Chrispin Mandiwa, Siyi Yang, Yuan Liang, Jing Yuan, Youjie Wang
BACKGROUND: The relationship between abortion and uterine fibroids has received little attention. The aim of the present study was to explore the association between number of induced and spontaneous abortions and the risk of uterine fibroids in middle-aged and older Chinese women. METHODS: A total of 14,595 retired female employees from the Dongfeng-Tongji cohort study were included in our analysis. Information on induced and spontaneous abortions was collected by trained interviewers through face-to-face interviews...
September 15, 2016: Journal of Women's Health
https://www.readbyqxmd.com/read/27629572/exposure-to-the-chinese-famine-in-childhood-increases-type-2-diabetes-risk-in-adults
#6
Jing Wang, Yaru Li, Xu Han, Bing Liu, Hua Hu, Fei Wang, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Frank B Hu, Tangchun Wu, Meian He
BACKGROUND: Evidence shows that exposure to poor conditions in early life is associated with an increased risk of chronic diseases in adults. OBJECTIVE: We investigated whether exposure to the Chinese famine (1959-1961) in the fetal stage or in childhood (0-9 y) was associated with type 2 diabetes (T2D) and hyperglycemia in adulthood. METHODS: We included 7801 subjects aged 56.4 ± 3.3 y from the Dongfeng-Tongji cohort. Subjects were classified into late-, middle-, and early-childhood-exposed, fetal-exposed, and unexposed groups...
September 14, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27607452/exposure-to-the-chinese-famine-in-early-life-and-hypertension-prevalence-risk-in-adults
#7
Caizheng Yu, Jing Wang, Yaru Li, Xu Han, Hua Hu, Fei Wang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Tangchun Wu, Meian He
OBJECTIVES: Famine exposure in early life has been reported to be associated with higher risk of hypertension prevalence in adults. The aim of the present study was to investigate the association of exposure to the Chinese famine during early life with the risk of hypertension prevalence in adults. METHODS: There were 8742 participants born between 1952 and 1964 derived from the Dongfeng-Tongji cohort included in the present study. Participants were classified as nonexposed group, fetal exposed group, early-childhood exposed group, mid-childhood exposed group, and late-childhood exposed group, respectively...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27558895/association-of-shift-work-daytime-napping-and-nighttime-sleep-with-cancer-incidence-and-cancer-caused-mortality-in-dongfeng-tongji-cohort-study
#8
Yansen Bai, Xiaoliang Li, Ke Wang, Shi Chen, Suhan Wang, Zhuowang Chen, Xiulong Wu, Wenshan Fu, Sheng Wei, Jing Yuan, Ping Yao, Xiaoping Miao, Xiaomin Zhang, Meian He, Handong Yang, Tangchun Wu, Huan Guo
BACKGROUND: Few studies investigated the combined effects of night-shift work, daytime napping, and nighttime sleep on cancer incidence and mortality. METHODS: A total of 25,377 participants were included in this study. Information on sleep habits, cancer incidences, and mortalities were collected. Cox proportional hazards models were used to calculate the adjusted hazard ratios and 95% confidence intervals (HRs, 95%CIs). RESULTS: Male subjects experienced ≥20 years of night-shift work, or without daytime napping had an increased risk of cancer, when compared with males who did not have night-shift work or napped for 1-30 min [HR (95%CI) = 1...
August 25, 2016: Annals of Medicine
https://www.readbyqxmd.com/read/27484402/association-between-bilirubin-and-risk-of-non-alcoholic-fatty-liver-disease-based-on-a-prospective-cohort-study
#9
Jianbo Tian, Rong Zhong, Cheng Liu, Yuhan Tang, Jing Gong, Jiang Chang, Jiao Lou, Juntao Ke, Jiaoyuan Li, Yi Zhang, Yang Yang, Ying Zhu, Yajie Gong, Yanyan Xu, Peiyi Liu, Xiao Yu, Lin Xiao, Min Du, Ling Yang, Jing Yuan, Youjie Wang, Weihong Chen, Sheng Wei, Yuan Liang, Xiaomin Zhang, Meian He, Tangchun Wu, Ping Yao, Xiaoping Miao
The study aimed to assess the association between total, direct, and indirect bilirubin and nonalcoholic fatty live disease (NAFLD) risk given its high prevalence and serious clinical prognosis. Among 27,009 subjects who participated in a healthy screening program from the Dongfeng-Tongji cohort study in 2008, 8189 eligible subjects (aged 35-86 years; males, 43.95%) were ultimately enrolled. The incidence rates of NAFLD in 2013 were compared with respect to baseline bilirubin levels among subjects free of NAFLD, and the effect sizes were estimated by logistic regression analysis...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27450688/sleep-duration-and-midday-napping-with-5-year-incidence-and-reversion-of-metabolic-syndrome-in-middle-aged-and-older-chinese
#10
Liangle Yang, Zengguang Xu, Meian He, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Francesca Angileri, Sébastien Légaré, Jing Yuan, Xiaoping Miao, Huan Guo, Ping Yao, Tangchun Wu, Xiaomin Zhang
STUDY OBJECTIVES: Prospective evidence on the association of sleep duration and midday napping with metabolic syndrome (MetS) is limited. We aimed to examine the associations of sleep duration and midday napping with risk of incidence and reversion of MetS and its components among a middle-aged and older Chinese population. METHODS: We included 14,399 subjects from the Dongfeng-Tongji (DFTJ) Cohort Study (2008-2013) who were free of coronary heart disease, stroke, and cancer at baseline...
November 1, 2016: Sleep
https://www.readbyqxmd.com/read/27327959/nighttime-sleep-duration-and-risk-of-nonalcoholic-fatty-liver-disease-the-dongfeng-tongji-prospective-study
#11
Cheng Liu, Rong Zhong, Jiao Lou, An Pan, Yuhan Tang, Jiang Chang, Juntao Ke, Jiaoyuan Li, Jing Yuan, Youjie Wang, Weihong Chen, Huan Guo, Sheng Wei, Yuan Liang, Xiaomin Zhang, Meian He, Frank B Hu, Tangchun Wu, Ping Yao, Xiaoping Miao
BACKGROUND: To examine the association between self-reported nighttime sleep duration and nonalcoholic fatty liver disease (NAFLD) risk by comparing the incidence rates of NAFLD among healthy subjects with different sleep duration during the 5 years follow-up. METHODS: 8965 eligible NAFLD-free subjects with a mean age of 61.6 years (males, 43.4%) from Dongfeng-Tongji cohort study at baseline were enrolled in the study. Logistic regression analysis was used to estimate the association between sleep duration and incident NAFLD with potential confounders adjusted...
June 21, 2016: Annals of Medicine
https://www.readbyqxmd.com/read/27087210/-dongfeng-tongji-cohort-methodology-of-the-survey-and-the-characteristics-of-baseline-and-initial-population-of-follow-up-program
#12
Meian He, Ce Zhang, Jiang Zhu, Ping Yao, Xiulou Li, Jing Yuan, Feng Wang, Yuewei Liu, Weihong Chen, Xinwen Min, Xu Han, Lei Guan, Jing Wang, Weimin Fang, Yuan Liang, Youjie Wang, Sheng Wei, Jichun Liu, Wenhu Si, Xiaoping Miao, Dongfeng Li, Jianru Zheng, Xiaomin Zhang, Huan Guo, Handong Yang, Frank B Hu, Tangchun Wu
OBJECTIVE: To explore the effects of related environment, occupational, lifestyle, genetic factors as well as their interactions on the etiology of major chronic diseases in an occupational population. METHODS: Dongfeng-Tongji cohort (DFTJ cohort), one of the large prospective cohort studies with biobank. Baseline study was conducted in Shiyan city, Hubei province from 2008 to 2009. This cohort study included questionnaire, physical examination and tests on blood samples...
April 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/27072746/green-tea-consumption-is-associated-with-reduced-incident-chd-and-improved-chd-related-biomarkers-in-the-dongfeng-tongji-cohort
#13
Chong Tian, Qiao Huang, Liangle Yang, Sébastien Légaré, Francesca Angileri, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Jing Yuan, Xiaoping Miao, Mei-an He, Tangchun Wu, Xiaomin Zhang
Prospective studies on the association of green tea with risk of coronary heart disease (CHD) incidence were scarce. This study examined whether green tea can reduce CHD incidence and have a beneficial effect on CHD-related risk markers in middle-aged and older Chinese population. We included 19,471 participants who were free of CHD, stroke or cancer at baseline from September 2008 to June 2010, and were followed until October 2013. Cox proportional hazard models were used to examine the hazard ratios (HR) of CHD incidence in relation to green tea consumption...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26969344/long-sleep-duration-and-afternoon-napping-are-associated-with-higher-risk-of-incident-diabetes-in-middle-aged-and-older-chinese-the-dongfeng-tongji-cohort-study
#14
Xu Han, Bing Liu, Jing Wang, An Pan, Yaru Li, Hua Hu, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Frank B Hu, Tangchun Wu, Meian He
BACKGROUND: In this study, we investigated the independent and combined effects of sleep duration and afternoon napping on the risk of incident diabetes among a cohort of middle-aged and older Chinese adults. METHODS: Information of sleep and napping was obtained by questionnaires during face-to-face interviews. We categorized sleep duration into <7 h, 7∼<8 h (reference), 8∼<9 h, 9∼<10 h, and ≥ 10 h. Afternoon napping was divided into no napping (0 min) (reference), 1-30 min, 31-60 min, 61-90 min, and > 90 min...
2016: Annals of Medicine
https://www.readbyqxmd.com/read/26607966/parity-and-risk-of-stroke-among-chinese-women-cross-sectional-evidence-from-the-dongfeng-tongji-cohort-study
#15
Yanmei Zhang, Lijun Shen, Jing Wu, Guiqiang Xu, Lulu Song, Siyi Yang, Yaohua Tian, Jing Yuan, Yuan Liang, Youjie Wang
Epidemiological studies have investigated the association between parity and the risk of stroke, but the results have been inconsistent. The objective of this study was to assess the association among middle-aged and older Chinese women. We used data from the Dongfeng-Tongji Cohort Study. In total, 14,277 women were included in the analysis. Participants were classified into four groups according to parity. Stroke cases were self-reported during face-to-face interviews. Multivariable logistic regression models were used to investigate the association between parity and the risk of stroke while controlling for potential confounders...
2015: Scientific Reports
https://www.readbyqxmd.com/read/26607032/parity-and-risk-of-coronary-heart-disease-in-middle-aged-and-older-chinese-women
#16
Lijun Shen, Jing Wu, Guiqiang Xu, Lulu Song, Siyi Yang, Jing Yuan, Yuan Liang, Youjie Wang
Pregnancy leads to physiological changes in lipid, glucose levels, and weight, which may increase the risk of coronary heart disease (CHD) in later life. The purpose of this study was to examine whether parity is associated with CHD in middle-aged and older Chinese women. A total of 20,207 women aged 37 to 94 years from Dongfeng-Tongji Cohort who completed the questionnaire, were medically examined and provided blood samples, were included in our analysis. CHD cases were determined by self-report of physician diagnosis through face-to-face interviews...
2015: Scientific Reports
https://www.readbyqxmd.com/read/26564127/longer-sleep-duration-and-midday-napping-are-associated-with-a-higher-risk-of-chd-incidence-in-middle-aged-and-older-chinese-the-dongfeng-tongji-cohort-study
#17
Liangle Yang, Handong Yang, Meian He, An Pan, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Xiaoyan Zhu, Jing Yuan, Sheng Wei, Xiaoping Miao, Frank B Hu, Tangchun Wu, Xiaomin Zhang
STUDY OBJECTIVES: To analyze the independent and combined relations of sleep duration and midday napping with coronary heart diseases (CHD) incidence along with the underlying changes of cardiovascular disease (CVD) risk factors among Chinese adults. METHODS: We included 19,370 individuals aged 62.8 years at baseline from September 2008 to June 2010, and they were followed until October 2013. Cox proportional hazards models and general linear models were used for multivariate longitudinal analyses...
2016: Sleep
https://www.readbyqxmd.com/read/26172999/parity-and-risk-of-metabolic-syndrome-among-chinese-women
#18
Jing Wu, Guiqiang Xu, Lijun Shen, Yanmei Zhang, Lulu Song, Siyi Yang, Handong Yang, Jing Yuan, Yuan Liang, Youjie Wang, Tangchun Wu
BACKGROUND: Studies regarding the effects of parity on metabolic syndrome in later life have produced conflicting results. The purpose of this study was to explore the association between parity and the risk of metabolic syndrome and its components in a population of Chinese women. METHODS: A cross-sectional study was performed in a total of 13,358 women (mean age 61.5 years) with at least one live birth from the Dongfeng-Tongji cohort study. Each woman completed baseline questionnaires and received baseline examination, including a physical examination and laboratory tests...
July 2015: Journal of Women's Health
https://www.readbyqxmd.com/read/26172433/helicobacter-pylori-infection-is-associated-with-type-2-diabetes-among-a-middle-and-old-age-chinese-population
#19
Xu Han, Yaru Li, Jing Wang, Bing Liu, Hua Hu, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Sheng Wei, Youjie Wang, Yuan Liang, Xiaoping Miao, Xiaomin Zhang, Huan Guo, Handong Yang, Tangchun Wu, Meian He
BACKGROUND: Although the association of Helicobacter pylori (H. pylori) infection with diabetes mellitus has been evaluated, findings are controversial. This study investigated the association in a Chinese population. METHODS: A cross-sectional study, including a total of 30 810 subjects from the Dongfeng-Tongji Cohort study, was conducted. H. pylori status was measured via (14) C urea breath test. Association analysis was performed by logistic regression, with multivariable adjustment for sex, age, body mass index, smoking, alcohol consumption, family history of diabetes, physical activity and the use of antibiotics...
January 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/26058081/association-of-adiposity-indices-with-platelet-distribution-width-and-mean-platelet-volume-in-chinese-adults
#20
Jian Hou, Chuanyao Liu, Ping Yao, Weihong Chen, Meian He, Youjie Wang, Yuan Liang, Xiaoping Miao, Sheng Wei, Tian Xu, Weimin Fang, Jiang Zhu, Xiulou Li, Frank B Hu, Tangchun Wu, Handong Yang, Jing Yuan
Hypoxia is a prominent characteristic of inflammatory tissue lesions. It can affect platelet function. While mean platelet volume (MPV) and platelet distribution width (PDW) are sample platelet indices, they may reflect subcinical platelet activation. To investigated associations between adiposity indices and platelet indices, 17327 eligible individuals (7677 males and 9650 females) from the Dongfeng-Tongji Cohort Study (DFTJ-Cohort Study, n=27009) were included in this study, except for 9682 individuals with missing data on demographical, lifestyle, physical indicators and diseases relative to PDW and MPV...
2015: PloS One
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