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Dongfeng-Tongji cohort

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https://www.readbyqxmd.com/read/28561804/corrigendum-green-tea-consumption-is-associated-with-reduced-incident-chd-and-improved-chd-related-biomarkers-in-the-dongfeng-tongji-cohort
#1
Chong Tian, Qiao Huang, Liangle Yang, Sébastien Légaré, Francesca Angileri, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Jing Yuan, Xiaoping Miao, Mei-An He, Tangchun Wu, Xiaomin Zhang
This corrects the article DOI: 10.1038/srep24353.
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28542413/association-of-drinking-pattern-with-risk-of-coronary-heart-disease-incidence-in-the-middle-aged-and-older-chinese-men-results-from-the-dongfeng-tongji-cohort
#2
Yizhi Zhang, Yanqiu Yu, Yu Yuan, Kuai Yu, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Meian He, Xiaomin Zhang, Tangchun Wu
BACKGROUND: Epidemiologic studies have found that moderate alcohol consumption was associated with a decreased risk of coronary heart disease (CHD) incidence. Nevertheless, whether the drinking pattern is associated with CHD incidence still remains inconclusive. METHODS: We included 8,469 Chinese men aged 45-81 years, who were free of CHD, stroke, or cancer at baseline from Dongfeng-Tongji cohort. A semi-structured questionnaire was used to collect information on alcohol consumption and other covariates...
2017: PloS One
https://www.readbyqxmd.com/read/28396588/association-between-education-and-the-risk-of-incident-coronary-heart-disease-among-middle-aged-and-older-chinese-the-dongfeng-tongji-cohort
#3
Hao Wang, Yu Yuan, Lulu Song, Gaokun Qiu, Xuefeng Lai, Liangle Yang, Yang Xiao, Lue Zhou, Handong Yang, Xiulou Li, Chengwei Xu, Xiaomin Zhang, Mei-An He, Tangchun Wu
Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifying effect of major CHD risk factors related to education in middle-aged and older Chinese adults. We included 18,551 participants with mean age 62.8 years at baseline between September 2008 and June 2010, and followed the population until October 2013...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28392079/effects-of-early-age-at-natural-menopause-on-coronary-heart-disease-and-stroke-in-chinese-women
#4
Lijun Shen, Lulu Song, Bingqing Liu, Hui Li, Xiaoxuan Zheng, Lina Zhang, Jing Yuan, Yuan Liang, Youjie Wang
BACKGROUND: Menopause is identified as a risk factor for cardiovascular disease because of the change of estrogen. The objective of the study was to explore the associations between early age at natural menopause (menopause at an age≤45years) and the presence of CHD and stroke. METHODS: The study subjects were from the first follow-up survey of the Dongfeng-Tongji cohort study. A total of 16,515 postmenopausal women were included for the analysis. Logistic regression models were used to examine the associations between age at natural menopause (≤45, 45-52, >52years) and the presence of CHD and stroke adjusted for sociodemographic characteristics, lifestyle, reproductive history and metabolic factors...
March 30, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28350839/bidirectional-association-between-nonalcoholic-fatty-liver-disease-and-type-2-diabetes-in-chinese-population-evidence-from-the-dongfeng-tongji-cohort-study
#5
Yaru Li, Jing Wang, Yuhan Tang, Xu Han, Bing Liu, Hua Hu, Xiulou Li, Kun Yang, Jing Yuan, Xiaoping Miao, Ping Yao, Sheng Wei, Youjie Wang, Yuan Liang, Xiaomin Zhang, Huan Guo, An Pan, Handong Yang, Frank B Hu, Tangchun Wu, Meian He
OBJECTIVES: The aim of this study is to examine the bidirectional association between nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM). METHODS: The data was derived from the Dongfeng-Tongji cohort study, which was established in 2008 and followed until October 2013. NAFLD was classified as none, mild, moderate/severe based on ultrasound examination. The analysis to examine the association between NAFLD and incident T2DM risk included 18,111 participants free of diabetes at baseline and the duration of follow-up was 4...
2017: PloS One
https://www.readbyqxmd.com/read/28176488/association-between-nighttime-sleep-duration-sleep-timing-and-falls-among-middle-aged-and-older-chinese-population-a-cross-sectional-analysis-from-the-dongfeng-tongji-cohort-study-china
#6
Yi Wang, Wending Li, Lijun Shen, Lulu Song, Hui Li, Bingqing Liu, Jing Yuan, Youjie Wang
AIM: To examine the association between nighttime sleep duration, sleep timing, and their interactive effect on falls among middle-aged and older Chinese adults. METHODS: The study sample of 35,465 (mean age 64.5 years) subjects were from the Dongfeng-Tongji cohort. All subjects completed baseline questionnaires and medical examinations. Participants were classified into five groups based on nighttime sleep duration: <7 h, 7- ≤ 8 h, 8- ≤ 9 h, 9- ≤ 10 h, ≥10 h, and three groups based on sleep timing: <21:00, 21:00- ≤ 23:00, ≥23:00...
February 8, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28164994/serum-bilirubin-levels-and-risk-of-type-2-diabetes-results-from-two-independent-cohorts-in-middle-aged-and-elderly-chinese
#7
Jing Wang, Yaru Li, Xu Han, Hua Hu, Fei Wang, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Cheng, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Jianmin Yuan, Woon-Puay Koh, Frank B Hu, Tangchun Wu, An Pan, Meian He
Serum bilirubin is a potent endogenous antioxidant and has been identified as cardiovascular risk in cohort studies, while the relation to type 2 diabetes (T2D) in the elderly remains unclear. We investigated both cross-sectional and prospective associations between serum bilirubin levels and T2D risk in the Dongfeng-Tongji (DFTJ) cohort, and replicated the prospective findings in a nested case-control study (509 cases and 509 controls) within the Singapore Chinese Health Study (SCHS). In the cross-sectional analysis of DFTJ cohort (15,575 participants with 2,532 diabetes cases), serum bilirubin levels (total, direct and indirect) increased in new on-set diabetes and decreased with the diabetic duration...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28129998/association-between-earlier-age-at-natural-menopause-and-risk-of-diabetes-in-middle-aged-and-older-chinese-women-the-dongfeng-tongji-cohort-study
#8
L Shen, L Song, H Li, B Liu, X Zheng, L Zhang, J Yuan, Y Liang, Y Wang
AIM: Age at menopause is associated with cardiovascular disease, but little is known of its relationship with diabetes, and previous findings are controversial. The objective of this study was to evaluate the association between earlier menopause (at age ≤45 years) and the prevalence of diabetes in the Chinese population. METHODS: A total of 16,299 postmenopausal women, aged 42.0-94.3 years, who completed the study questionnaires, underwent medical examinations and provided blood samples, were included in our analysis...
January 24, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/28051177/association-of-regular-physical-activity-with-total-and-cause-specific-mortality-among-middle-aged-and-older-chinese-a-prospective-cohort-study
#9
Yun Zhou, Runbo Zhang, Yuewei Liu, Yanjun Guo, Dongming Wang, Meian He, Jing Yuan, Yuan Liang, Xiaomin Zhang, Youjie Wang, Huan Guo, Sheng Wei, Xiaoping Miao, Ping Yao, Tangchun Wu, Weihong Chen
Association between physical activity and mortality has rarely been investigated among the Chinese population. Furthermore, the most appropriate amount of physical activity for longevity benefits remains unclear. We used data from the Dongfeng-Tongji cohort, including 24,606 middle-aged and older retired adults in 2008 and followed to 2013, to quantify linear and non-linear dose-response relationships between regular physical activity and mortality risks by Cox proportional hazards model. Compared with participants who did not engage in regular physical activity, those performing regular physical activity had significantly 46%, 56%, and 49% decreased risks of mortality from all causes, circulatory, and respiratory diseases, respectively...
January 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28000763/height-and-prevalence-of-hypertension-in-a-middle-aged-and-older-chinese-population
#10
Lulu Song, Lijun Shen, Hui Li, Bingqing Liu, Xiaoxuan Zheng, Yuan Liang, Jing Yuan, Youjie Wang
Evidence from epidemiological studies reported that height was inversely associated with cardiovascular diseases, but the association between height and hypertension was unclear. The purpose of this study was to explore the association between height and blood pressure or prevalence of hypertension in a middle-aged and older Chinese population. A total of 33,197 participants aged 37 to 94 years were recruited from the Dongfeng-Tongji cohort study in Hubei province, China. All participants completed baseline questionnaires, medical examinations and provided blood samples...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27968834/methylation-loci-associated-with-body-mass-index-waist-circumference-and-waist-to-hip-ratio-in-chinese-adults-an-epigenome-wide-analysis
#11
Biqi Wang, Wenjing Gao, Jun Li, Canqing Yu, Weihua Cao, Jun Lv, Zengchang Pang, Liming Cong, Hua Wang, Xianping Wu, Liming Liang, Tangchun Wu, Liming Li
BACKGROUND: DNA methylation has been implicated in the pathology of obesity, but little is known about such epigenetic variants in Chinese people. We conducted an epigenome-wide analysis of methylation at CpG sites in relation to body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) among Chinese adult populations. METHODS: 469 twins from the Chinese National Twin Registry were the discovery cohort. After quality control, methylation levels in whole blood leukocyte DNA were tested for association with BMI, WC, and WHR using mixed linear regressions, adjusting for demographics, lifestyle, and family structure...
October 2016: Lancet
https://www.readbyqxmd.com/read/27933515/serum-bilirubin-concentrations-and-incident-coronary-heart-disease-risk-among-patients-with-type-2-diabetes-the-dongfeng-tongji-cohort
#12
Jing Wang, Xiaofen Wu, Yaru Li, Xu Han, Hua Hu, Fei Wang, Caizheng Yu, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Huan Guo, Handong Yang, Tangchun Wu, Xiaomin Zhang, Meian He
AIMS: Elevated serum bilirubin levels are associated with decreased coronary heart disease (CHD) risk in cross-sectional studies among diabetic patients, but prospective evidence is limited. We investigated the relationship of serum bilirubin levels with incident CHD risk among type 2 diabetes patients. METHODS: In a prospective study of 2918 type 2 diabetes embedded in the Dongfeng-Tongji cohort, serum total bilirubin (TBil), direct bilirubin (DBil), and indirect bilirubin (IBil) were measured at baseline...
March 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/27795732/association-between-parity-and-obesity-patterns-in-a-middle-aged-and-older-chinese-population-a-cross-sectional-analysis-in-the-tongji-dongfeng-cohort-study
#13
Wending Li, Yi Wang, Lijun Shen, Lulu Song, Hui Li, Bingqing Liu, Jing Yuan, Youjie Wang
BACKGROUND: Higher parity has been implicated as a risk factor for obesity of women. The objective of the study was to examine whether parity was associated with general obesity or abdominal obesity, or both, among middle-aged and older Chinese women. METHODS: A total of 12,829 Chinese women (mean age: 64.8 years) with at least one live birth were selected from the Dongfeng-Tongji Cohort Study (phase II). We used body mass index to assess general obesity, and waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and waist circumference (WC) to assess abdominal obesity...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27752898/parity-and-risk-of-ovarian-cysts-cross-sectional-evidence-from-the-dongfeng-tongji-cohort-study
#14
Chrispin Mandiwa, Li-Jun Shen, Yao-Hua Tian, Lu-Lu Song, Gui-Qiang Xu, Si-Yi Yang, Yuan Liang, Jing Yuan, You-Jie Wang
Little is known about the association between parity and the risk of ovarian cysts. The aim of this study was to examine the association between parity and the risk of ovarian cysts among a population of Chinese women. A total of 20 502 women aged 45-86 years from the Dongfeng-Tongji Cohort study completed baseline questionnaires, medical examination and provided baseline blood samples. Participants were categorized into four groups according to parity (one, two, three, and four or more live births). Logistic regression models were used to investigate the association between parity and the risk of ovarian cysts...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27694567/plasma-metabolomics-identified-novel-metabolites-associated-with-risk-of-type-2-diabetes-in-two-prospective-cohorts-of-chinese-adults
#15
Gaokun Qiu, Yan Zheng, Hao Wang, Jie Sun, Hongxia Ma, Yang Xiao, Yizhun Li, Yu Yuan, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Chengwei Xu, Yue Jiang, Xiaomin Zhang, Meian He, Ming Yang, Zhibin Hu, Huiru Tang, Hongbing Shen, Frank B Hu, An Pan, Tangchun Wu
BACKGROUND: Metabolomics studies in Caucasians have identified a number of novel metabolites in association with the risk of type 2 diabetes (T2D). However, few prospective metabolomic studies are available in Chinese populations. In the present study, we sought to identify novel metabolites consistently associated with incident T2D in two independent cohorts of Chinese adults. METHODS: We performed targeted metabolomics (52 metabolites) of fasting plasma samples by liquid chromatography-mass spectrometry in two prospective case-control studies nested within the Dongfeng-Tongji (DFTJ) cohort and Jiangsu Non-communicable Disease (JSNCD) cohort...
October 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27665401/dose-response-relationship-between-serum-uric-acid-levels-and-risk-of-incident-coronary-heart-disease-in-the-dongfeng-tongji-cohort
#16
Xuefeng Lai, Liangle Yang, Sébastien Légaré, Francesca Angileri, Xuguang Chen, Qin Fang, Handong Yang, Ce Zhang, Xiulou Li, Xinwen Min, Chengwei Xu, Jing Yuan, Mei-An He, Tangchun Wu, Xiaomin Zhang
BACKGROUND: In prospective studies, relationship of serum uric acid (SUA) with risk of coronary heart disease (CHD) incidence is inconsistent. We evaluated the association of SUA with incident CHD and the potential modifying effect of major CHD risk factors related to SUA among a middle aged and elderly Chinese population. METHODS: We included 16, 063 participants who were free of CHD, stroke, cancer and renal diseases at baseline from Sep. 2008 to June 2010, and were followed until Oct...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27632700/induced-and-spontaneous-abortion-and-risk-of-uterine-fibroids
#17
Lulu Song, Lijun Shen, Chrispin Mandiwa, Siyi Yang, Yuan Liang, Jing Yuan, Youjie Wang
BACKGROUND: The relationship between abortion and uterine fibroids has received little attention. The aim of the present study was to explore the association between number of induced and spontaneous abortions and the risk of uterine fibroids in middle-aged and older Chinese women. METHODS: A total of 14,595 retired female employees from the Dongfeng-Tongji cohort study were included in our analysis. Information on induced and spontaneous abortions was collected by trained interviewers through face-to-face interviews...
January 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/27629572/exposure-to-the-chinese-famine-in-childhood-increases-type-2-diabetes-risk-in-adults
#18
Jing Wang, Yaru Li, Xu Han, Bing Liu, Hua Hu, Fei Wang, Xiulou Li, Kun Yang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Frank B Hu, Tangchun Wu, Meian He
BACKGROUND: Evidence shows that exposure to poor conditions in early life is associated with an increased risk of chronic diseases in adults. OBJECTIVE: We investigated whether exposure to the Chinese famine (1959-1961) in the fetal stage or in childhood (0-9 y) was associated with type 2 diabetes (T2D) and hyperglycemia in adulthood. METHODS: We included 7801 subjects aged 56.4 ± 3.3 y from the Dongfeng-Tongji cohort. Subjects were classified into late-, middle-, and early-childhood-exposed, fetal-exposed, and unexposed groups...
November 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27607452/exposure-to-the-chinese-famine-in-early-life-and-hypertension-prevalence-risk-in-adults
#19
Caizheng Yu, Jing Wang, Yaru Li, Xu Han, Hua Hu, Fei Wang, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Tangchun Wu, Meian He
OBJECTIVES: Famine exposure in early life has been reported to be associated with higher risk of hypertension prevalence in adults. The aim of the present study was to investigate the association of exposure to the Chinese famine during early life with the risk of hypertension prevalence in adults. METHODS: There were 8742 participants born between 1952 and 1964 derived from the Dongfeng-Tongji cohort included in the present study. Participants were classified as nonexposed group, fetal exposed group, early-childhood exposed group, mid-childhood exposed group, and late-childhood exposed group, respectively...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27558895/association-of-shift-work-daytime-napping-and-nighttime-sleep-with-cancer-incidence-and-cancer-caused-mortality-in-dongfeng-tongji-cohort-study
#20
Yansen Bai, Xiaoliang Li, Ke Wang, Shi Chen, Suhan Wang, Zhuowang Chen, Xiulong Wu, Wenshan Fu, Sheng Wei, Jing Yuan, Ping Yao, Xiaoping Miao, Xiaomin Zhang, Meian He, Handong Yang, Tangchun Wu, Huan Guo
BACKGROUND: Few studies investigated the combined effects of night-shift work, daytime napping, and nighttime sleep on cancer incidence and mortality. METHODS: A total of 25,377 participants were included in this study. Information on sleep habits, cancer incidences, and mortalities were collected. Cox proportional hazards models were used to calculate the adjusted hazard ratios and 95% confidence intervals (HRs, 95%CIs). RESULTS: Male subjects experienced ≥20 years of night-shift work, or without daytime napping had an increased risk of cancer, when compared with males who did not have night-shift work or napped for 1-30 min [HR (95%CI) = 1...
December 2016: Annals of Medicine
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