keyword
MENU ▼
Read by QxMD icon Read
search

Iron absorption

keyword
https://www.readbyqxmd.com/read/28218331/ultrafast-photochemistry-of-the-bc1-complex
#1
Marten H Vos, Brandon J Reeder, Fevzi Daldal, Ursula Liebl
We present a full investigation of ultrafast light-induced events in the membraneous cytochrome bc1 complex by transient absorption spectroscopy. This energy-transducing complex harbors four redox-active components per monomer: heme c1, two 6-coordinate b-hemes and a [2Fe-2S] cluster. Using excitation of these components in different ratios under various excitation conditions, probing in the full visible range and under three well-defined redox conditions, we demonstrate that for all ferrous hemes of the complex photodissociation of axial ligands takes place and that they rebind in 5-7 ps, as in other 6-coordinate heme proteins, including cytoglobin, which is included as a reference in this study...
February 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28216263/new-insights-into-iron-deficiency-and-iron-deficiency-anemia
#2
REVIEW
Clara Camaschella
Recent advances in iron metabolism have stimulated new interest in iron deficiency (ID) and its anemia (IDA), common conditions worldwide. Absolute ID/IDA, i.e. the decrease of total body iron, is easily diagnosed based on decreased levels of serum ferritin and transferrin saturation. Relative lack of iron in specific organs/tissues, and IDA in the context of inflammatory disorders, are diagnosed based on arbitrary cut offs of ferritin and transferrin saturation and/or marker combination (as the soluble transferrin receptor/ferritin index) in an appropriate clinical context...
February 13, 2017: Blood Reviews
https://www.readbyqxmd.com/read/28205062/gallium-ferredoxin-as-a-tool-to-study-the-effects-of-ferredoxin-binding-to-photosystem-i-without-ferredoxin-reduction
#3
Clara Mignée, Risa Mutoh, Anja Krieger-Liszkay, Genji Kurisu, Pierre Sétif
Reduction of ferredoxin by photosystem I (PSI) involves the [4Fe-4S] clusters FA and FB harbored by PsaC, with FB being the direct electron transfer partner of ferredoxin (Fd). Binding of the redox-inactive gallium ferredoxin to PSI was investigated by flash-absorption spectroscopy, studying both the P700(+) decay and the reduction of the native iron Fd in the presence of FdGa. FdGa binding resulted in a faster recombination between P700(+) and (FA, FB)(-), a slower electron escape from (FA, FB)(-) to exogenous acceptors, and a decreased amount of intracomplex FdFe reduction, in accordance with competitive binding between FdFe and FdGa...
February 15, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28202241/geochemical-and-mineralogical-characterization-of-sulfur-and-iron-in-coal-waste-rock-elk-valley-british-columbia-canada
#4
Joseph Essilfie-Dughan, M Jim Hendry, James J Dynes, Yongfeng Hu, Ashis Biswas, S Lee Barbour, S Day
Exposure of coal waste rock to atmospheric oxygen can result in the oxidation of sulfide minerals and the release of sulfate (SO4(2-)) and associated trace elements (e.g., Se, As, Cd, and Zn) to groundwaters and surface waters. Similarly, reduced iron minerals such as siderite, ankerite, and the sulfide, pyrite, present in the waste rock can also undergo oxidation, resulting in the formation of iron oxyhydroxides that can adsorb trace elements released from the oxidation of the sulfide minerals. Characterization and quantification of the distribution of sulfide and iron minerals, their oxidation products, as well as leaching rates are critical to assessing present-day and future impacts of SO4(2-) and associated trace elements on receiving waters...
February 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28196881/engineered-holocytochrome-c-synthases-that-biosynthesize-new-cytochromes-c
#5
Deanna L Mendez, Shalon E Babbitt, Jeremy D King, John D'Alessandro, Michael B Watson, Robert E Blankenship, Liviu M Mirica, Robert G Kranz
Cytochrome c (cyt c), required for electron transport in mitochondria, possesses a covalently attached heme cofactor. Attachment is catalyzed by holocytochrome c synthase (HCCS), leading to two thioether bonds between heme and a conserved CXXCH motif of cyt c In cyt c, histidine (His19) of CXXCH acts as an axial ligand to heme iron and upon release of holocytochrome c from HCCS, folding leads to formation of a second axial interaction with methionine (Met81). We previously discovered mutations in human HCCS that facilitate increased biosynthesis of cyt c in recombinant Escherichia coli Focusing on HCCS E159A, novel cyt c variants in quantities that are sufficient for biophysical analysis are biosynthesized...
February 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28196533/assessment-of-complementary-feeding-of-canadian-infants-effects-on-microbiome-oxidative-stress-a-randomized-controlled-trial
#6
Wafaa Qasem, Meghan B Azad, Zakir Hossain, Elnaz Azad, Sarah Jorgensen, Sandra Castillo San Juan, Chenxi Cai, Ehsan Khafipour, Trust Beta, L Jackson Roberts, James Friel
BACKGROUND: The World Health Organization recommends exclusive breastfeeding until 6 months followed by introduction of iron-rich complementary foods (CFs). The aim of this study was to determine the impact of different iron-rich CFs on infant gut inflammation and microbiota. METHODS: Eighty-seven exclusively breastfed infants were randomly assigned to receive one of the following as their first CF: iron-fortified cereal (Cer), iron-fortified cereal with fruit (Cer + Fr), or meat (M)...
February 14, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28195138/bioproduction-characterization-anticancer-and-antioxidant-activities-of-extracellular-melanin-pigment-produced-by-newly-isolated-microbial-cell-factories-streptomyces-glaucescens-neae-h
#7
Noura El-Ahmady El-Naggar, Sara M El-Ewasy
In this present study, a newly isolated strain, Streptomyces sp. NEAE-H, capable of producing high amount of black extracellular melanin pigment on peptone-yeast extract iron agar and identified as Streptomyces glaucescens NEAE-H. Plackett-Burman statistical design was conducted for initial screening of 17 independent (assigned) variables for their significances on melanin pigment production by Streptomyces glaucescens NEAE-H. The most significant factors affecting melanin production are incubation period, protease-peptone and ferric ammonium citrate...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28193158/transcriptional-and-physiological-analyses-of-fe-deficiency-response-in-maize-reveal-the-presence-of-strategy-i-components-and-fe-p-interactions
#8
Laura Zanin, Silvia Venuti, Anita Zamboni, Zeno Varanini, Nicola Tomasi, Roberto Pinton
BACKGROUND: Under limited iron (Fe) availability maize, a Strategy II plant, improves Fe acquisition through the release of phytosiderophores (PS) into the rhizosphere and the subsequent uptake of Fe-PS complexes into root cells. Occurrence of Strategy-I-like components and interactions with phosphorous (P) nutrition has been hypothesized based on molecular and physiological studies in grasses. RESULTS: In this report transcriptomic analysis (NimbleGen microarray) of Fe deficiency response revealed that maize roots modulated the expression levels of 724 genes (508 up- and 216 down-regulated, respectively)...
February 13, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28191970/various-arsenic-network-structures-in-112-type-ca1-xlaxfe1-ypdyas2-revealed-by-synchrotron-x-ray-diffraction-experiments
#9
Shinya Tamura, Naoyuki Katayama, Yuto Yamada, Yuki Sugiyama, Kento Sugawara, Hiroshi Sawa
Two novel 112-type palladium-doped iron arsenides were synthesized and identified using comprehensive studies involving synchrotron X-ray diffraction and X-ray absorption near-edge structure (XANES) experiments. Whereas in-plane arsenic zigzag chains were found in the 112-type superconducting iron arsenide Ca1-xLaxFeAs2 with maximum Tc = 34 K, deformed arsenic network structures appeared in other 112-type materials, such as longitudinal arsenic zigzag chains in CaFe1-yPdyAs2 (y ∼ 0.51) and arsenic square sheets constructed via hypervalent bonding in Ca1-xLaxFe1-yPdyAs2 (x ∼ 0...
February 13, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28190843/application-of-internal-standard-method-for-several-3d-transition-metallic-elements-in-flame-atomic-absorption-spectrometry-using-a-multi-wavelength-high-resolution-spectrometer
#10
Yusuke Toya, Toshiko Itagaki, Kazuaki Wagatsuma
We investigated a simultaneous internal standard method in flame atomic absorption spectrometry (FAAS), in order to better the analytical precision of 3d-transition metals contained in steel materials. For this purpose, a new spectrometer system for FAAS, comprising a bright xenon lamp as the primary radiation source and a high-resolution Echelle monochromator, was employed to measure several absorption lines at a wavelength width of ca. 0.3 nm at the same time, which enables the absorbances of an analytical line and also an internal standard line to be estimated...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/28183672/in-vitro-biocompatibility-of-a-ferrimagnetic-glass-ceramic-for-hyperthermia-application
#11
Oana Bretcanu, Marta Miola, Claudia L Bianchi, Ida Marangi, Roberta Carbone, Ingrid Corazzari, Mario Cannas, Enrica Verné
Ferrimagnetic glass-ceramics containing magnetite crystals were developed for hyperthermia applications of solid neoplastic tissue. The present work is focused on in vitro evaluation of the biocompatibility of these materials, before and after soaking in a simulated body fluid (SBF). X-ray diffraction, scanning electron microscopy, atomic absorption spectrophotometry, X-ray photoelectron spectrometry and pH measurements were employed in glass-ceramic characterisation. The free-radical mediated reactivity of the glass-ceramic was evaluated by Electron Paramagnetic Resonance (EPR) spin trapping...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183017/effect-of-the-redox-dynamics-on-microbial-mediated-as-transformation-coupled-with-fe-and-s-in-flow-through-sediment-columns
#12
Hee Sun Moon, Bo-A Kim, Sung Pil Hyun, Yoon-Ho Lee, Doyun Shin
Arsenic (As) biogeochemistry coupled with iron (Fe) and sulfur (S) was studied using columns packed with As(V)-contaminated sediments under two phases: a reduction phase followed by an oxidation phase. During the reduction phase, four identical columns inoculated with G. sulfurreducens were stimulated with 3mM acetate for 60days. The As(III) in the effluent rapidly increased then gradually decreased. The Fe(II) and sulfate concentration indicated ferrous sulfide precipitation inside the column after day 14 and X-ray absorption near edge structure spectra showed that As(III) was enriched at the column outlet...
January 22, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28182578/review-of-heavy-metal-accumulation-on-aquatic-environment-in-northern-east-mediterrenean-sea-part-i-some-essential-metals
#13
Ayşe Bahar Yılmaz, Alper Yanar, Ela Nur Alkan
All pollutants can reach the aquatic environments and the levels of heavy metals in upper members of the food web like fish can reach values many times higher than those found in aquatic environment or in sediments. Although heavy metals are essential or non-essential, all heavy metals are potentially harmful to humans and most organisms at some level of exposure and absorption. Marine organisms are good indicators for long-term monitoring of metal accumulation. The present review study is for evaluation of the data from previous studies about the toxic effects of selected heavy metals, like essential metals (copper, zinc, iron, chromium, and manganese), on seawater, sediment, and in different tissues of aquatic animals (demersal and bentic fish, invertabres) collected from different areas in Northern East Mediterrenean Sea since the 1990s...
February 9, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28169552/lactoferrin-and-the-lactoferrin-sophorolipids-assembly-can-be-internalized-by-dermal-fibroblasts-and-regulate-gene-expression
#14
Rulan Jiang, Yasushi A Suzuki, Xiaogu Du, Bo Lönnerdal
Lactoferrin (Lf) is an iron-binding multifunctional protein, mainly present in external secretions. Lf is known to penetrate skin and may thus exert its multiple functions in skin. Sophorolipids (SLs) are glycolipid biosurfactants, which have been shown to enhance absorption of commercial bovine Lf (CbLf) in model skin via forming an assembly with CbLf. In this study, uptake and post-internalization localization of bovine Lf (bLf), CbLf, and human Lf (hLf) with or without forming assemblies with SLs in human dermal fibroblasts (HDFn) were determined using (125)I-labeled Lfs and confocal microscopy, respectively...
February 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28166624/self-assembly-directed-aerogel-and-membrane-formation-from-a-magnetic-composite-an-approach-to-develop-multifunctional-materials
#15
Balachandran Vivek, Edamana Prasad
Herein, we report the preparation of an aerogel and a membrane from a magnetic composite material by tuning the self-assembly at the molecular level. The gel exhibits excellent oil absorption property and the membrane shows remarkable autonomous self-healing property. The composite is formed from organosilicon modified poly(amido amine) {PAMAM} dendrimer, which are linked with iron oxide nanoparticles and poly vinyl alcohol (PVA). Upon addition of a cross-linker (formaldehyde), the system undergoes a fast self-assembly and gelation process...
February 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28153964/anemia-in-peritoneal-dialysis-patients-iron-repletion-current-and-future-therapies
#16
REVIEW
Ahmed Zeidan, Sunil Bhandari
Iron deficiency, both functional and absolute, is common in patients with chronic kidney disease (CKD), especially those requiring dialysis. Guidelines advocate treatment of iron-deficiency anemia in patients with CKD and those on peritoneal dialysis (PD). Oral iron is often insufficient and slow to improve hemoglobin concentrations because of high hepcidin levels causing impaired absorption and mobilization, while intravenous (IV) supplementation replenishes and maintains iron stores more effectively and is now standard practice (Kidney Disease Improving Global Outcomes [KDIGO] 2012 guidelines)...
January 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28153426/factors-affecting-gastrointestinal-absorption-of-levothyroxine-a-review
#17
REVIEW
Marko Skelin, Tomo Lucijanić, Daniela Amidžić Klarić, Arnes Rešić, Miro Bakula, Ana-Marija Liberati-Čizmek, Hossein Gharib, Dario Rahelić
PURPOSE: Levothyroxine (LT4) is a drug with a narrow therapeutic index, applied in small amounts (micrograms), which makes interactions in the absorption phase clinically significant. The main aim of this article was to review and present the latest information on factors that affect the gastrointestinal absorption of this drug. METHODS: Relevant data were collected by using the MEDLINE, PubMed, EMBASE, Web of Science, Science Direct, and Scopus databases with the key words levothyroxine and absorption...
January 30, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28151917/chronic-diarrhea-associated-with-high-serum-level-of-immunoglobulin-a-and-diffuse-infiltration-of-plasma-cell-in-small-intestine-a-case-report
#18
Junwen Yang, Shuijiao Chen, Linlin Chen, Miao Ouyang, Fujun Li
RATIONALE: Chronic diarrhea in adult patients due to various causes is very common in clinic, but patient suffering with mal-absorption due to immunoproliferative small intestinal disease was rarely reported in China. PATIENT CONCERNS AND DIAGNOSES: A 35-year-old female presented with more than three years history of chronic diarrhea, rickets, high serum value of immunoglobulin A protein, and anemia. Bone marrow aspiration suggested that the patient was in a sideropenic and megalobastic anemia stage...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28150114/a-theoretical-and-experimental-study-of-calcium-iron-zinc-cadmium-and-sodium-ions-absorption-by-aspartame
#19
Karim Mahnam, Fatame Raisi
Aspartame (L-Aspartyl-L-phenylalanine methyl ester) is a sweet dipeptide used in some foods and beverages. Experimental studies show that aspartame causes osteoporosis and some illnesses, which are similar to those of copper and calcium deficiency. This raises the issue that aspartame in food may interact with cations and excrete them from the body. This study aimed to study aspartame interaction with calcium, zinc, iron, sodium, and cadmium ions via molecular dynamics simulation (MD) and spectroscopy. Following a 480-ns molecular dynamics simulation, it became clear that the aspartame is able to sequester Fe(2+), Ca(2+), Cd(2+), and Zn(2+) ions for a long time...
February 1, 2017: Journal of Biological Physics
https://www.readbyqxmd.com/read/28148685/iron-bioavailability-from-ferric-pyrophosphate-in-extruded-rice-cofortified-with-zinc-sulfate-is-greater-than-when-cofortified-with-zinc-oxide-in-a-human-stable-isotope-study
#20
Laura Hackl, Michael B Zimmermann, Christophe Zeder, Megan Parker, Paul W Johns, Richard F Hurrell, Diego Moretti
BACKGROUND: Extruded rice grains are often cofortified with iron and zinc. However, it is uncertain if the addition of zinc to iron-fortified rice affects iron absorption and whether this is zinc-compound specific. OBJECTIVE: We investigated whether zinc, added as zinc oxide (ZnO) or zinc sulfate (ZnSO4), affects human iron absorption from extruded rice fortified with ferric pyrophosphate (FePP). METHODS: In 19 iron-depleted Swiss women (plasma ferritin ≤16...
February 1, 2017: Journal of Nutrition
keyword
keyword
30738
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"