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Vitamin absorption

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https://www.readbyqxmd.com/read/29665730/comparative-assessment-and-suitability-of-iron-and-the-nutritional-composition-of-fortified-foods-for-young-children
#1
Majed M AbuKhader
AIM: To assess the suitability of iron content and the nutritional benefits of selected fortified food products marketed for 4-8 year old children in Oman. METHODS: Forty-five fortified foods, which are available in Omani markets, were classified into four groups based on food type and composition: ready-to-eat (RTE) breakfast cereals (two groups), malted milk drinks and milk powder formulas. The nutrition panel displayed on the products' outer package was used as a source of content values for iron and other nutrients...
January 1, 2018: Nutrition and Health
https://www.readbyqxmd.com/read/29663691/an-evaluation-of-the-antiaging-properties-of-strawberry-hydrolysate-treatment-enriched-with-l-ascorbic-acid-applied-with-microneedle-mesotherapy
#2
Agata Markiewicz, Malwina Zasada, Anna Erkiert-Polguj, Marzena Wieckowska-Szakiel, Elzbieta Budzisz
BACKGROUND: Mature skin is characterized by a loss of elasticity, hyperpigmentation, and dehydration. L-ascorbic acid stimulates the synthesis of collagen type I, inhibits melanogenesis, and helps to maintain correct skin hydration. Combining microneedle mesotherapy with the application of preparations rich in vitamin C results in better therapeutic effects due to the improved absorption of active substances. The study evaluates the effectiveness of the application of strawberry hydrolysate enriched with L-ascorbic acid using microneedle mesotherapy...
April 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29663261/evaluation-of-diffusion-tensor-imaging-changes-and-neurocognitive-effects-of-asymptomatic-vitamin-b12-deficiency
#3
Ali Zeynal Abidin Tak, Erdal Dayan, Hacı Taner Bulut
Vitamin B12 plays an important role in the mechanisms which are responsible for myelinization in the central nervous system. It can particularly lead to hematological and neuropsychiatric symptoms when serum levels fall due to insufficient intake with diet or absorption problems. The purpose of this study was to show the cognitive effects in vitamin B12 deficiency cases that have not reached clinical symptom level using neuropsychological tests, and to show possible cerebral neuronal damage using diffusion tensor imaging (DTI) method...
April 16, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29656297/reducing-mineral-and-vitamin-deficiencies-through-biofortification-progress-under-harvestplus
#4
Howarth Bouis
Fundamentally, the prevalence of mineral and vitamin deficiencies is high in developing countries due to the fact that agricultural systems do not produce sufficient foods rich in minerals and vitamins. Biofortification involves breeding staple food crops to increase their micronutrient content, targeting staple foods widely consumed by low-income families globally. In so doing, biofortification contributes to solving the underlying problem of mineral and vitamin deficiencies by increasing the amount of iron, zinc, and provitamin A produced by food systems...
April 13, 2018: World Review of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29650340/longitudinal-evaluation-of-efficacy-safety-and-nutritional-status-during-one-year-treatment-with-the-duodenal-jejunal-bypass-liner
#5
Nina Riedel, Katharina Laubner, Anne Lautenbach, Gerhard Schön, Matthias Schlensak, Rainer Stengel, Thomas Eberl, Frank Dederichs, Jens Aberle, Jochen Seufert
BACKGROUND: The endoscopic duodenal-jejunal bypass liner (DJBL) represents a novel temporary endoscopic approach for treatment of obesity-associated type 2 diabetes. Recent results from the German DJBL registry confirmed substantial positive metabolic effects of the DJBL in type 2 diabetes. However, the last Food and Drug Administration trial was stopped due to a high occurrence of hepatic abscesses (3.5%). OBJECTIVES: Here, we analyzed time courses of development of co-morbidities, nutritive changes, and occurrence of adverse events during the 1-year treatment phase with the DJBL in the German DJBL registry...
March 9, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29597231/physiology-of-the-calcium-parathyroid-hormone-vitamin-d-axis
#6
David Goltzman, Michael Mannstadt, Claudio Marcocci
Classic endocrine feedback loops ensure the regulation of blood calcium. Calcium in the extracellular fluid (ECF) binds and activates the calcium sensing receptor (CaSR) on the parathyroid cells, leading to an increase in intracellular calcium. This in turn leads to a reduced parathyroid hormone (PTH) release. Hypocalcemia leads to the opposite sequence of events, namely, lowered intracellular calcium and increased PTH production and secretion. PTH rapidly increases renal calcium reabsorption and, over hours to days, enhances osteoclastic bone resorption and liberates both calcium and phosphate from the skeleton...
2018: Frontiers of Hormone Research
https://www.readbyqxmd.com/read/29596284/a-case-of-wernicke-encephalopathy-developing-after-ileal-bypass-surgery
#7
Tülay Kamaşak, Sibel Kul, Mustafa Tuşat, Nezir Ozgun, Ali Cansu
Wernicke encephalopathy is an acute neurological problem resulting from thiamine deficiency and manifesting with mental confusion, oculomotor dysfunction, and ataxia. It is associated with alcohol dependence in adults. Preparatory factors include hyperemesis gravidarum, prolonged diarrhea, prolonged parental nutrition without vitamin support, absorption disorders, anorexia, cancer, and chemotherapy. Failure to consider the clinical findings and preparatory factors of this disease, which is rare in children, can delay diagnosis...
March 28, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29579913/absorption-kinetics-of-vitamin-e-nanoemulsion-and-green-tea-microstructures-by-intestinal-in-situ-single-perfusion-technique-in-rats
#8
Rijuta Ganesh Saratale, Hee-Seok Lee, Yong Eui Koo, Ganesh Dattatraya Saratale, Young Jun Kim, Jee Young Imm, Yooheon Park
The absorption kinetics of food ingredients such as nanoemulsified vitamin E and green tea microstructures were evaluated by the intestinal in situ single perfusion technique. Absorption rate, sub-acute oral toxicity and organ morphology in a rat model were examined. The intestinal in situ single perfusion technique and HPLC analysis were applied to investigate the absorption rate of selected materials by examining time-dependent changes in the serum levels of catechin and dl-α-tocopherol. The acute toxicity test and histopathological evaluation were applied to analyze the safety of microsized green tea and nanosized vitamin E in a rat model...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29577902/identification-of-aberrant-circular-rna-expression-and-its-potential-clinical-value-in-primary-great-saphenous-vein-varicosities
#9
Wan Zhang, Li Li, Yi Si, Zhenyu Shi, Ting Zhu, Shunjiu Zhuang, Weiguo Fu
This study aimed to identify aberrant circRNA expression in primary great saphenous vein varicosities (PGSVVs) and investigate its potential clinical significance. High-throughput sequencing was applied to analyze the differential expression of circRNAs in three paired vein samples of PGSVVs and a control group. Computational bioinformatics analyses, including gene ontology (GO) analysis and encyclopedia of genes and genomes (KEGG) pathway analysis, were performed to further enrich microRNA data. Real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was used to verify the selected aberrant circRNAs in all vein samples, and a receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic and potential clinical significance...
March 22, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29562593/vitamin-d-hypercalciuria-and-kidney-stones
#10
REVIEW
Emmanuel Letavernier, Michel Daudon
The estimated lifetime risk of nephrolithiasis is growing nowadays, and the formation of kidney stones is frequently promoted by hypercalciuria. Vitamin D, and especially its active metabolite calcitriol, increase digestive calcium absorption-as urinary calcium excretion is directly correlated with digestive calcium absorption, vitamin D metabolites could theoretically increase calciuria and promote urinary stone formation. Nevertheless, there was, until recently, low evidence that 25-hydroxyvitamin D serum levels would be correlated with kidney stone formation, even if high calcitriol concentrations are frequently observed in hypercalciuric stone formers...
March 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29560588/pet-imaging-analysis-of-vitamin-b-1-kinetics-with-11-c-thiamine-and-its-derivative-11-c-thiamine-tetrahydrofurfuryl-disulfide-in-rats
#11
Satoshi Nozaki, Aya Mawatari, Yuka Nakatani, Emi Hayashinaka, Yasuhiro Wada, Yukihiro Nomura, Takahito Kitayoshi, Kouji Akimoto, Shinji Ninomiya, Hisashi Doi, Yasuyoshi Watanabe
PURPOSE: Thiamine is an essential component of glucose metabolism and energy production. The disulfide derivative, thiamine tetrahydrofurfuryl disulfide (TTFD), is better absorbed than readily-available water-soluble thiamine salts because it does not require the rate-limiting transport system required for thiamine absorption. However, the detailed pharmacokinetics of thiamine and TTFD under normal and pathological conditions have not yet been clarified. C-11-labeled thiamine and TTFD were recently synthesized by our group...
March 20, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29546369/how-ultraviolet-light-touches-the-brain-and-endocrine-system-through-skin-and-why
#12
Andrzej T Slominski, Michal A Zmijewski, Przemyslaw M Plonka, Jerzy P Szaflarski, Ralf Paus
The skin, a self-regulating protective barrier organ, is empowered with sensory and computing capabilities to counteract the environmental stressors to maintain/restore disrupted cutaneous homeostasis. These complex functions are coordinated by a cutaneous neuro-endocrine system that also communicates in a bidirectional fashion with the central nervous, endocrine and immune systems, all acting in concert to control body homeostasis. While ultraviolet energy (UV) has played an important role in the origin and evolution of life, UV absorption by the skin not only triggers mechanisms that defend skin integrity and regulate global homeostasis, but also induces skin pathology (e...
March 12, 2018: Endocrinology
https://www.readbyqxmd.com/read/29541858/assessment-of-dietary-intake-and-mineral-status-in-pregnant-women
#13
Rafał Kocyłowski, Iwona Lewicka, Mariusz Grzesiak, Zuzanna Gaj, Anna Sobańska, Joanna Poznaniak, Constantin von Kaisenberg, Joanna Suliburska
PURPOSE: To evaluate the dietary intake of pregnant women and their nutritional status of Ca, Mg, Fe, Zn, and Cu, as the nutritional status of pregnant women is an important factor for the proper progression of a pregnancy and the development and health of the foetus. METHODS: The study was conducted on 108 pregnant women ages 18-42, at 6-32 weeks of gestation. We used a questionnaire and a 24-h recall nutrition interview. Hair samples were taken for testing and the level of each mineral was assessed using atomic absorption spectrometry...
March 14, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29533710/a-food-derived-dietary-supplement-containing-a-low-dose-of-iron-improved-markers-of-iron-status-among-nonanemic-iron-deficient-women
#14
Christopher R D'Adamo, James S Novick, Termeh M Feinberg, Valerie J Dawson, Larry E Miller
OBJECTIVE: Iron deficiency is the most common nutrient deficiency in the world. While deficiency can often be resolved through dietary supplementation with iron, adverse events are common and frequently preclude compliance. The objective of this study was to determine whether a food-derived dietary supplement containing a low dose of iron and nutrients that increase iron absorption could resolve iron deficiency with fewer adverse events than reported at higher doses. METHODS: A pilot clinical trial (NCT02683369) was conducted among premenopausal women with nonanemic iron deficiency that was verified by blood screening...
March 13, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29521205/bile-acid-derivatives-from-old-molecules-to-a-new-potent-therapeutical-use-an-overview
#15
Marine Blanchet, Jean Michel Brunel
Bile acids or bile salts, belong to a large family of biological steroid derivatives found predominantly in the bile of mammals and other vertebrates. These amphipathic molecules possess numerous functions, including eliminating cholesterol from the body, driving the flow of bile to eliminate catabolites, emulsifying fat-soluble vitamins to enable their absorption, aiding in motility and in reducing the bacteria flora found in the small intestine and biliary tract. In this review, we investigate progress towards synthetic bile acid derivatives, with special emphasis on how they might be used for various biological applications and the challenges that remain in developing these compounds as potent drugs of the future especially in the field of microbiology (antimicrobial activities) and cancer (anticancer agents)...
March 8, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29515522/targeting-fibroblast-growth-factor-23-signaling-with-antibodies-and-inhibitors-is-there-a-rationale
#16
REVIEW
Seiji Fukumoto
Fibroblast growth factor 23 (FGF23) is a phosphotropic hormone mainly produced by bone. FGF23 reduces serum phosphate by suppressing intestinal phosphate absorption through reducing 1,25-dihydroxyvitamin D and proximal tubular phosphate reabsorption. Excessive actions of FG23 result in several kinds of hypophosphatemic rickets/osteomalacia including X-linked hypophosphatemic rickets (XLH) and tumor-induced osteomalacia. While neutral phosphate and active vitamin D are standard therapies for child patients with XLH, these medications have several limitations both in their effects and adverse events...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29508210/biochemical-characterization-of-the-cytochrome-p450-cyp107cb2-from-bacillus-lehensis-g1
#17
Swi See Ang, Abu Bakar Salleh, Leow Thean Chor, Yahaya M Normi, Bimo Ario Tejo, Mohd Basyaruddin Abdul Rahman, Mariam-Aisha Fatima
The bioconversion of vitamin D3 catalyzed by cytochrome P450 (CYP) requires 25-hydroxylation and subsequent 1α-hydroxylation to produce the hormonal activated 1α,25-dihydroxyvitamin D3. Vitamin D3 25-hydroxylase catalyses the first step in the vitamin D3 biosynthetic pathway, essential in the de novo activation of vitamin D3. A CYP known as CYP107CB2 has been identified as a novel vitamin D hydroxylase in Bacillus lehensis G1. In order to deepen the understanding of this bacterial origin CYP107CB2, its detailed biological functions as well as biochemical characteristics were defined...
March 5, 2018: Protein Journal
https://www.readbyqxmd.com/read/29506877/early-changes-in-vitamin-b12-uptake-and-biomarker-status-following-roux-en-y-gastric-bypass-and-sleeve-gastrectomy
#18
L S Kornerup, C L Hvas, C B Abild, B Richelsen, E Nexo
BACKGROUND & AIMS: Bariatric surgery increases the risk of micronutrient deficiencies, including vitamin B12 (B12) deficiency. We analysed early changes in biomarkers of B12 status following bariatric surgery. METHODS: We prospectively included adult patients (n = 27) referred for either Roux-en-Y Gastric Bypass (RYGB) (n = 19) or Sleeve Gastrectomy (SG) (n = 8). Blood samples were drawn before surgery and 2 and 6 months following surgery for measurement of B12, holotranscobalamin (holoTC), and methylmalonic acid (MMA)...
February 15, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29505151/single-center-experience-with-the-use-of-teduglutide-in-adult-patients-with-short-bowel-syndrome
#19
Kwai Lam, Lauren Schwartz, Jennifer Batisti, Kishore R Iyer
BACKGROUND: Teduglutide is a glucagon-like peptide 2 (GLP-2) analog that has been approved for the treatment of adult short bowel syndrome (SBS)-associated intestinal failure (IF; SBS-IF). Teduglutide increases villus height and crypt depth in the small bowel mucosa, promoting nutrition absorption and enteral independence from parenteral nutrition (PN). We aim to report our single-center experience with teduglutide in adult patients with SBS to provide real-world context to its use. METHOD: We conducted a retrospective analysis on patients managed within our tertiary-level intestinal rehabilitation program to identify patients with SBS-IF treated with teduglutide from 2009-2015...
January 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29500722/vitamin-k2-in-multiple-sclerosis-patients
#20
Reza Lasemi, Michael Kundi, Nahid Beladi Moghadam, Hanns Moshammer, Johannes A Hainfellner
BACKGROUND: Vitamin K2 (VK2) belongs to the vitamin K family and comprises a number of subtypes differing in length of side chains consisting of isoprenoid groups (menaquinone-n, MK-n). It is essential for a number of physiological functions although the full spectrum of activity has not yet been elucidated. Due to its role in protection of mitochondrial damage, VK2 could be relevant in preventing disease progress in multiple sclerosis (MS). METHODS: We measured VK2 serum levels by the double antibody sandwich Enzyme-linked Immunosorbent Assay (ELISA) technique in MS patients and age and sex matched controls, both under vitamin D supplementation, and related it to disease characteristics and treatment...
March 2, 2018: Wiener Klinische Wochenschrift
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