keyword
MENU ▼
Read by QxMD icon Read
search

chamberlain

keyword
https://www.readbyqxmd.com/read/28646594/prevalence-and-prognosis-of-low-volume-oligorecurrent-hormone-sensitive-prostate-cancer-amenable-to-lesion-ablative-therapy
#1
Aurélie De Bruycker, Bieke Lambert, Tom Claeys, Louke Delrue, Chamberlain Mbah, Gert De Meerleer, Geert Villeirs, Filip De Vos, Kathia De Man, Karel Decaestecker, Valérie Fonteyne, Nicolaas Lumen, Filip Ameye, Ignace Billiet, Steven Joniau, Friedl Vanhaverbeke, Wim Duthoy, Piet Ost
OBJECTIVES: To describe the anatomical patterns of PCa recurrence following primary therapy and investigate if patients with low-volume disease have a better prognosis as compared to their counterparts. MATERIAL AND METHODS: Patients eligible for a F18-choline PET-CT were entered in a prospective cohort study. Eligible patients had an asymptomatic biochemical recurrence following primary PCa treatment and testosterone levels >50 ng/ml. The number of lesions were counted per scan...
June 24, 2017: BJU International
https://www.readbyqxmd.com/read/28646372/psychophysiological-and-behavioral-responses-to-a-novel-intruder-threat-task-for-children-on-the-autism-spectrum
#2
Mikle South, Katherine M Taylor, Tiffani Newton, Megan Christensen, Nathan K Jamison, Paul Chamberlain, Oliver Johnston, Michael J Crowley, J Dee Higley
We measured skin conductance response (SCR) to escalating levels of a direct social threat from a novel, ecologically-relevant experimental paradigm, the Intruder Threat Task. We simultaneously evaluated the contribution of social symptom severity and behavioral movement. Children with AS group showed less psychophysiological reactivity to social threat than controls across all three phases of the experiment. In the AS group, greater social impairment was significantly associated with reduced SCR. However, movement activity predicted SCR while diagnosis did not...
June 23, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28643914/the-use-of-cell-culture-platforms-to-identify-novel-markers-of-bone-and-dentin-resorption
#3
W J Rody, O Krokhin, V Spicer, C A Chamberlain, M Chamberlain, K P McHugh, S M Wallet, A K Emory, J D Crull, L S Holliday
OBJECTIVES: 1) To test the hypothesis that there would be proteomic differences in the composition of exosomes isolated from osteoclasts and odontoclasts and 2) to determine the clinical usefulness of these in vitro biomarker candidates. MATERIALS AND METHODS: Mouse bone marrow-derived precursors were cultured on either dentin or bone slices and allowed to mature and begin resorption. Exosomes were isolated from cell culture media and characterized by mass spectrometry...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28643790/corrigendum-muscle-specific-crispr-cas9-dystrophin-gene-editing-ameliorates-pathophysiology-in-a-mouse-model-for-duchenne-muscular-dystrophy
#4
Niclas E Bengtsson, John K Hall, Guy L Odom, Michael P Phelps, Colin R Andrus, R David Hawkins, Stephen D Hauschka, Joel R Chamberlain, Jeffrey S Chamberlain
This corrects the article DOI: 10.1038/ncomms14454.
June 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28638176/gallbladder-carcinoma-in-the-united-states-a-population-based-clinical-outcomes-study-involving-22-343-patients-from-the-surveillance-epidemiology-and-end-result-database-1973-2013
#5
Christine S M Lau, Aleksander Zywot, Krishnaraj Mahendraraj, Ronald S Chamberlain
INTRODUCTION: Gallbladder carcinoma (GBC) is the most common malignancy of the biliary tract and the third most common gastrointestinal tract malignancy. This study examines a large cohort of GBC patients in the United States in an effort to define demographics, clinical, and pathologic features impacting clinical outcomes. METHODS: Demographic and clinical data on 22,343 GBC patients was abstracted from the SEER database (1973-2013). RESULTS: GBC was presented most often among Caucasian (63...
2017: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/28628502/placebo-response-in-trichotillomania
#6
Jon E Grant, Samuel R Chamberlain, Sarah A Redden, Brian L Odlaug, Michael van Ameringen, Darin D Dougherty, Nancy J Keuthen, Suck W Kim
Trichotillomania is a functionally impairing, often overlooked disorder with no Food and Drug Administration-approved medications indicated for its treatment. The ability of clinical trials to detect the beneficial effects of pharmacologic treatment in trichotillomania has been hampered by the high placebo response rate. Very little is known about baseline demographic and clinical characteristics that may be predictive of placebo response in such patients. Overall, 104 participants assigned to placebo were pooled from five double-blind trials conducted at three sites in the USA and Canada...
June 16, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28620036/substrate-selectivity-in-the-zdhhc-family-of-s-acyltransferases
#7
REVIEW
Kimon Lemonidis, Christine Salaun, Marianna Kouskou, Cinta Diez-Ardanuy, Luke H Chamberlain, Jennifer Greaves
S-acylation is a reversible lipid modification occurring on cysteine residues mediated by a family of membrane-bound 'zDHHC' enzymes. S-acylation predominantly results in anchoring of soluble proteins to membrane compartments or in the trafficking of membrane proteins to different compartments. Recent work has shown that although S-acylation of some proteins may involve very weak interactions with zDHHC enzymes, a pool of zDHHC enzymes exhibit strong and specific interactions with substrates, thereby recruiting them for S-acylation...
June 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28619878/clarification-to-prison-litigation-reform-act-three-strikes-rule
#8
Vivek Datta, Tania M Michaels, John R Chamberlain
No abstract text is available yet for this article.
June 2017: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/28619877/government-management-of-accompanied-minors-held-in-the-custody-of-immigration-authorities
#9
James A Armontrout, John R Chamberlain
No abstract text is available yet for this article.
June 2017: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/28613084/perceived-social-support-and-self-care-in-patients-hospitalized-with-heart-failure
#10
Lyne Chamberlain
BACKGROUND: Rehospitalization of heart failure patients is often considered the result of inadequate self-care yet only one study documents superior outcomes with better self-care. AIMS: If inadequate self-care is related to hospitalizations, then hospitalized heart failure patients should have lower self-care skills than non-hospitalized patients. The purpose of this study was to evaluate perceived social support and self-care characteristics of patients hospitalized with an exacerbation of heart failure...
June 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28611741/glycosylation-of-a-capsule-like-complex-clc-by-francisella-novicida-is-required-for-virulence-and-partial-protective-immunity-in-mice
#11
Kelly C Freudenberger Catanzaro, Anna E Champion, Nrusingh Mohapatra, Thomas Cecere, Thomas J Inzana
Francisella tularensis is a Gram-negative bacterium and the etiologic agent of tularemia. F. tularensis may appear encapsulated when examined by transmission electron microscopy (TEM), which is due to production of an extracellular capsule-like complex (CLC) when the bacterium is grown under specific environmental conditions. Deletion of two glycosylation genes in the live vaccine strain (LVS) results in loss of apparent CLC and attenuation of LVS in mice. In contrast, F. novicida, which is also highly virulent for mice, is reported to be non-encapsulated...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28609498/treatment-of-a-mandibular-glandular-odontogenic-cyst-with-peripheral-ostectomy-bone-allograft-and-implant-reconstruction-a-case-report
#12
Christopher T Barth, John A Chamberlain, Jeffrey R Wessel
This article reports on a case of a glandular odontogenic cyst (GOC) in the posterior mandible of a 25-year-old male treated with peripheral ostectomy, bone allograft, and an implant-supported fixed dental prosthesis. During a routine 3-month postoperative visit, a radiograph suggested vertical bone loss on the implant in the location of the mandibular right first molar. The three-walled defect was surgically treated with debridement, bone allograft, and a membrane. Healing of this site has been uneventful...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28608787/is-patient-reported-exposure-a-reliable-indicator-for-anogenital-gonorrhea-and-chlamydia-screening-in-young-black-men-who-have-sex-with-men
#13
Nicholas Chamberlain, Richard A Crosby, Leandro Mena, Philip A Chan, Kenneth H Mayer
Among 485 young black men who have sex with men recruited in Jackson, MS, 90-day anal sexual exposure significantly predicted rectal infection, but 19.4% of rectal infections would have been missed among men denying receptive anal sex. Reports of consistent condom use were associated with lower infection rates only in men reporting insertive anal sex.
July 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28604891/pre-concentration-by-liquid-intake-by-paper-p-clip-a-new-technique-for-large-volumes-and-digital-microfluidics
#14
Darius G Rackus, Richard P S de Campos, Calvin Chan, Maria M Karcz, Brendon Seale, Tanya Narahari, Christopher Dixon, M Dean Chamberlain, Aaron R Wheeler
Microfluidic platforms are an attractive option for incorporating complex fluid handling into low-cost and rapid diagnostic tests. A persistent challenge for microfluidics, however, is the mismatch in the "world-to-chip" interface - it is challenging to detect analytes present at low concentrations in systems that can only handle small volumes of sample. Here we describe a new technique termed pre-concentration by liquid intake by paper (P-CLIP) that addresses this mismatch, allowing digital microfluidics to interface with volumes on the order of hundreds of microliters...
June 12, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28602452/disease-severity-presentation-and-clinical-outcomes-among-adolescents-with-malignant-breast-neoplasms-a-20-year-population-based-outcomes-study-from-the-seer-database-1973-2009
#15
Vijayashree Murthy, Shonali Pawar, Ronald S Chamberlain
INTRODUCTION: Primary breast cancer in adolescents is extremely rare and thus is not widely studied. This study aimed to evaluate trends, characteristics, and outcomes among a cohort of adolescents with breast cancer. PATIENTS AND METHODS: A total of 657,712 female patients with breast cancer from Surveillance Epidemiology and End Results (SEER) database (1973-2009) were analyzed, and 91 adolescents were identified. Three age groups (under 20 years, 20-50 years or premenopausal, and > 50 years or postmenopausal) were compared for tumor size, stage, receptor status, and outcomes...
May 8, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28573556/the-influence-of-bone-loss-on-the-three-adult-age-markers-of-the-innominate
#16
Carme Rissech, Jo Appleby, Alessandra Cosso, Francisco Reina, Anna Carrera, Richard Thomas
To evaluate the influence of bone loss on the three adult age markers of the innominate, 30 males and 30 females aged between 16 and 80 years coming from the British Coventry collection were analyzed. The pubic symphysis, auricular surface, and acetabulum age variables were evaluated following the descriptions of Schmitt, Buckberry-Chamberlain, and Rissech, respectively. The second metacarpal cortical index was used to evaluate bone loss. Possible sexual differences in metrical variables were explored by a Student t-test taking into account the entire sample...
June 1, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28560882/gambling-disorder-association-between-duration-of-illness-clinical-and-neurocognitive-variables
#17
Gustavo C Medeiros, Sarah A Redden, Samuel R Chamberlain, Jon E Grant
Background and aims Gambling disorder (GD) may have its onset in a wide range of ages, from adolescents to old adults. In addition, individuals with GD tend to seek treatment at different moments in their lives. As a result of these characteristics (variable age at onset and variable age at treatment seeking), we find subjects with diverse duration of illness (DOI) in clinical practice. DOI is an important but relatively understudied factor in GD. Our objective was to investigate clinical and neurocognitive characteristics associated with different DOI...
May 31, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28557973/cerebrospinal-fluid-dissemination-and-neoplastic-meningitis-in-primary-brain-tumors
#18
Sajeel Chowdhary, Sherri Damlo, Marc C Chamberlain
BACKGROUND: Neoplastic meningitis, also known as leptomeningeal disease, affects the entire neuraxis. The clinical manifestations of the disease may affect the cranial nerves, cerebral hemispheres, or the spine. Because of the extent of disease involvement, treatment options and disease staging should involve all compartments of the cerebrospinal fluid (CSF) and subarachnoid space. Few studies of patients with primary brain tumors have specifically addressed treatment for the secondary complication of neoplastic meningitis...
January 2017: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/28553667/translation-of-cardiac-myosin-activation-with-2-deoxy-atp-to-treat-heart-failure-via-an-experimental-ribonucleotide-reductase-based-gene-therapy
#19
Kassandra S Thomson, Guy L Odom, Charles E Murry, Gregory G Mahairas, Farid Moussavi-Harami, Sam L Teichman, Xiaolan Chen, Stephen D Hauschka, Jeffrey S Chamberlain, Michael Regnier
Despite recent advances, chronic heart failure remains a significant and growing unmet medical need, reaching epidemic proportions carrying substantial morbidity, mortality, and costs. A safe and convenient therapeutic agent that produces sustained inotropic effects could ameliorate symptoms, and improve functional capacity and quality of life. We discovered small amounts of 2-deoxy-ATP (dATP) activate cardiac myosin leading to enhanced contractility in normal and failing heart muscle. Cardiac myosin activation triggers faster myosin crossbridge cycling with greater force generation during each contraction...
December 2016: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28540346/less-invasive-surfactant-administration-reduces-the-need-for-mechanical-ventilation-in-preterm-infants-a-meta-analysis
#20
Christine S M Lau, Ronald S Chamberlain, Shyan Sun
Neonatal respiratory distress syndrome due to surfactant deficiency is associated with high morbidity and mortality in preterm infants, and the use of less invasive surfactant administration (LISA) has been increasingly studied. This meta-analysis found that LISA via thin catheter significantly reduced the need for mechanical ventilation within the first 72 hours (relative risk [RR] = 0.677; P = .021), duration of mechanical ventilation (difference in means [MD] = -39.302 hours; P < .001), duration of supplemental oxygen (MD = -68...
2017: Global Pediatric Health
keyword
keyword
30731
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"