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https://www.readbyqxmd.com/read/29150972/patient-level-factors-and-the-quality-of-care-delivered-in-pediatric-emergency-departments
#1
James P Marcin, Patrick S Romano, Parul Dayal, Madan Dharmar, James M Chamberlain, Nanette Dudley, Charles G Macias, Lise E Nigrovic, Elizabeth C Powell, Alexander J Rogers, Meridith Sonnett, Leah Tzimenatos, Elizabeth R Alpern, Rebecca Andrews-Dickert, Dominic A Borgialli, Erika Sidney, T Charles Casper, J Michael Dean, Nathan Kuppermann
OBJECTIVE: Quality of care delivered to adult patients in the emergency department (ED) is often associated with demographic and clinical factors such as a patient's race/ethnicity and insurance status. We sought to determine whether the quality of care delivered to children in the ED was associated with a variety of patient-level factors. METHODS: This was a retrospective, observational cohort study. Pediatric patients (<18 years) who received care between January 2011 and December 2011 at one of twelve EDs participating in the Pediatric Emergency Care Applied Research Network (PECARN) were included...
November 18, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29148264/negative-symptoms-in-first-episode-psychosis-clinical-correlates-and-1-year-follow-up-outcomes-in-london-early-intervention-services
#2
Aikaterini Rammou, Helen L Fisher, Sonia Johnson, Barnaby Major, Nikola Rahaman, Nick Chamberlain-Kent, James M Stone
AIM: Negative symptoms (NS) have been associated with poor outcome and remain difficult to treat in patients with psychosis. This study examined the association of NS with clinical features at first presentation to mental health services for psychosis and with outcomes at 1-year follow-up. METHODS: Clinical data were utilized from five London Early Intervention Services (EIS) included in the MiData audit database. The sample comprised 484 first-episode psychosis patients with complete Positive and Negative Syndrome Scale data at baseline and 1-year follow-up...
November 16, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29143331/implicit-review-instrument-to-evaluate-quality-of-care-delivered-by-physicians-to-children-in-emergency-departments
#3
James P Marcin, Patrick S Romano, Madan Dharmar, James M Chamberlain, Nanette Dudley, Charles G Macias, Lise E Nigrovic, Elizabeth C Powell, Alexander J Rogers, Meridith Sonnett, Leah Tzimenatos, Elizabeth R Alpern, Rebecca Andrews-Dickert, Dominic A Borgialli, Erika Sidney, Charlie Casper, Jonathan Michael Dean, Nathan Kuppermann
OBJECTIVE: To evaluate the consistency, reliability, and validity of an implicit review instrument that measures the quality of care provided to children in the emergency department (ED). DATA SOURCES/STUDY SETTING: Medical records of randomly selected children from 12 EDs in the Pediatric Emergency Care Applied Research Network (PECARN). STUDY DESIGN: Eight pediatric emergency medicine physicians applied the instrument to 620 medical records...
November 16, 2017: Health Services Research
https://www.readbyqxmd.com/read/29139509/nexafs-spectroscopy-of-ionic-liquids-experiments-versus-calculations
#4
Richard M Fogarty, Richard P Matthews, Matthew T Clough, Claire R Ashworth, Agnieszka Brandt-Talbot, Paul J Corbett, Robert G Palgrave, Richard A Bourne, Thomas W Chamberlain, Tom Vander Hoogerstraete, Paul B J Thompson, Patricia A Hunt, Nicholas A Besley, Kevin R J Lovelock
Experimental near edge X-ray absorption fine structure (NEXAFS) spectra are reported for 12 ionic liquids (ILs) encompassing a range of chemical structures for both the sulfur 1s and nitrogen 1s edges and compared with time-dependent density functional theory (TD-DFT) calculations. The energy scales for the experimental data were carefully calibrated against literature data. Gas phase calculations were performed on lone ions, ion pairs and ion pair dimers, with a wide range of ion pair conformers considered...
November 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29095388/identifying-nonprovider-factors-affecting-pediatric-emergency-medicine-provider-efficiency
#5
Fareed Saleh, Kristen Breslin, Paul C Mullan, Zachary Tillett, James M Chamberlain
OBJECTIVE: The aim of this study was to create a multivariable model of standardized relative value units per hour by adjusting for nonprovider factors that influence efficiency. METHODS: We obtained productivity data based on billing records measured in emergency relative value units for (1) both evaluation and management of visits and (2) procedures for 16 pediatric emergency medicine providers with more than 750 hours worked per year. Eligible shifts were in an urban, academic pediatric emergency department (ED) with 2 sites: a tertiary care main campus and a satellite community site...
October 31, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29080260/non-linearities-in-bird-responses-across-urbanisation-gradients-a-meta-analysis
#6
Péter Batáry, Kornélia Kurucz, Marcela Suarez-Rubio, Dan E Chamberlain
Urbanisation is one of the most extreme forms of environmental alteration, posing a major threat to biodiversity. We studied the effects of urbanisation on avian communities via a systematic review using hierarchical and categorical meta-analyses. Altogether, we found 42 observations from 37 case studies for species richness and 23 observations from 20 case studies for abundance. Urbanisation had an overall strong negative effect on bird species richness, whereas abundance increased marginally with urbanisation...
October 28, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29074757/ethics-of-maternal-vaccination
#7
A T Chamberlain, J V Lavery, A White, S B Omer
No abstract text is available yet for this article.
October 27, 2017: Science
https://www.readbyqxmd.com/read/29068464/atomic-charges-of-sulfur-in-ionic-liquids-experiments-and-calculations
#8
Richard M Fogarty, Rebecca Rowe, Richard P Matthews, Matthew T Clough, Claire R Ashworth, Agnieszka Brandt, Paul J Corbett, Robert G Palgrave, Emily F Smith, Richard A Bourne, Thomas W Chamberlain, Paul B J Thompson, Patricia A Hunt, Kevin R J Lovelock
Experimental near edge X-ray absorption fine structure (NEXAFS) spectra, X-ray photoelectron (XP) spectra and Auger electron spectra are reported for sulfur in ionic liquids (ILs) with a range of chemical structures. These values provide experimental measures of the atomic charge in each IL and enable the evaluation of the suitability of NEXAFS spectroscopy and XPS for probing the relative atomic charge of sulfur. In addition, we use Auger electron spectroscopy to show that when XPS binding energies differ by less than 0...
October 25, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/29067669/aav6-vector-production-and-purification-for-muscle-gene-therapy
#9
Christine L Halbert, James M Allen, Jeffrey S Chamberlain
Vectors derived from adeno-associated viruses (AAV) have been generated using numerous naturally occurring and synthetic serotypes of the virus. Such vectors have proven to be extremely useful for a variety of gene transfer studies, both in vitro and in vivo, and are increasingly being used in gene therapy protocols for a variety of human disorders. Methods to produce AAV vectors typically rely on co-transfection of several different plasmid vectors that carry the transgene of interest (the gene to be delivered , in a "transfer plasmid") and helper genes needed for AAV vector replication and packaging (helper plasmids)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29066003/clinical-outcomes-after-burns-in-elderly-patients-over-70-years-a-17-year-retrospective-analysis
#10
Gregg Dexter, Sachin Patil, Kanwardeep Singh, Michael A Marano, Robin Lee, Sylvia J Petrone, Ronald S Chamberlain
INTRODUCTION: In the United Stated population >70years is likely to double by the year 2050. Elderly population (>70years) are most vulnerable to burns and outcomes following such injuries in this special group is poorly studied. This study aimed to look at outcomes following burns in patients >70years over a period of 17 years. MATERIALS AND METHODS: Data on 6512 patients admitted to a Level I Burn Center between 1995 and 2011 was analyzed. Age, gender, ethnicity, TBSA, burn etiology, hospital and burn intensive care unit (ICU) length of stay (LOS) and status at discharge were abstracted...
October 20, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29060142/classification-of-voluntary-coughs-applied-to-the-screening-of-respiratory-disease
#11
Christian Infante, Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher
Pulmonary and respiratory diseases (e.g. asthma, COPD, allergies, pneumonia, tuberculosis, etc.) represent a large proportion of the global disease burden, mortality, and disability. In this context of creating automated diagnostic tools, we explore how the analysis of voluntary cough sounds may be used to screen for pulmonary disease. As a clinical study, voluntary coughs were recorded using a custom mobile phone stethoscope from 54 patients, of which 7 had COPD, 15 had asthma, 11 had allergic rhinitis, 17 had both asthma and allergic rhinitis, and four had both COPD and allergic rhinitis...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29056097/paths-to-improving-care-of-australian-aboriginal-and-torres-strait-islander-women-following-gestational-diabetes-corrigendum
#12
Sandra Campbell, Nicolette Roux, Cilla Preece, Eileen Rafter, Bronwyn Davis, Jackie Mein, Jacqueline Boyle, Bronwyn Fredericks, Catherine Chamberlain
No abstract text is available yet for this article.
October 23, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29049512/time-requirements-for-electronic-health-record-use-in-an-academic-ophthalmology-center
#13
Sarah Read-Brown, Michelle R Hribar, Leah G Reznick, Lorinna H Lombardi, Mansi Parikh, Winston D Chamberlain, Steven T Bailey, Jessica B Wallace, Thomas R Yackel, Michael F Chiang
Importance: Electronic health record (EHR) systems have transformed the practice of medicine. However, physicians have raised concerns that EHR time requirements have negatively affected their productivity. Meanwhile, evolving approaches toward physician reimbursement will require additional documentation to measure quality and cost of care. To date, little quantitative analysis has rigorously studied these topics. Objective: To examine ophthalmologist time requirements for EHR use...
November 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29048958/shade-sails-and-passive-recreation-in-public-parks-of-melbourne-and-denver-a-randomized-intervention
#14
RANDOMIZED CONTROLLED TRIAL
David B Buller, Dallas R English, Mary Klein Buller, Jody Simmons, James A Chamberlain, Melanie Wakefield, Suzanne Dobbinson
OBJECTIVES: To test whether shade sails will increase the use of passive recreation areas (PRAs). METHODS: We conducted a stratified randomized pretest-posttest controlled design study in Melbourne, Australia, and Denver, Colorado, in 2010 to 2014. We randomized a sample of 144 public parks with 2 PRAs in full sun in a 1:3 ratio to treatment or control. Shade sails were built at 1 PRA per treatment park. The outcome was any use of the study PRA (n = 576 pretest and n = 576 posttest observations; 100% follow-up)...
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29040319/habitat-selection-and-diurnal-refugia-of-gray-foxes-in-southwestern-georgia-usa
#15
Nicholas R Deuel, L Mike Conner, Karl V Miller, Michael J Chamberlain, Michael J Cherry, Larry V Tannenbaum
Understanding habitat selection of gray foxes (Urocyon cinereoargenteus) is essential to evaluate their potential response to changes in land use and predator communities. Few studies have evaluated temporal habitat selection or explicitly identified habitats used by gray foxes for diurnal refugia. We used GPS collars to obtain location data for 34 gray foxes (20 males and 14 females) from February 2014 to December 2015 to evaluate temporal (seasonal and diel) habitat selection and selection of diurnal refugia in southwestern Georgia, USA...
2017: PloS One
https://www.readbyqxmd.com/read/29040133/what-s-new-in-shoulder-and-elbow-surgery
#16
Aaron M Chamberlain, Alexander Aleem, Jay D Keener
No abstract text is available yet for this article.
October 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29036632/mapping-compulsivity-in-the-dsm-5-obsessive-compulsive-and-related-disorders-cognitive-domains-neural-circuitry-and-treatment
#17
Naomi A Fineberg, Annemieke M Apergis-Schoute, M Matilde Vaghi, Paula Banca, Claire M Gillan, Valerie Voon, Samuel R Chamberlain, Cinosi Eduardo, Reid Jemma, Sonia Shahper, Edward T Bullmore, Barbara J Sahakian, Trevor W Robbins
Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm. Growing evidence suggests that the neurocognitive mechanisms mediating behavioural inhibition (motor inhibition, cognitive inflexibility) reversal learning and habit formation (shift from goal-directed to habitual responding) contribute toward compulsive activity in a broad range of disorders. In obsessive compulsive disorder (OCD), distributed network perturbation appears focussed around the pre-frontal cortex, caudate, putamen and associated neuro-circuitry...
September 23, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29036581/secondary-use-of-electronic-health-record-data-for-clinical-workflow-analysis
#18
Michelle R Hribar, Sarah Read-Brown, Isaac H Goldstein, Leah G Reznick, Lorinna Lombardi, Mansi Parikh, Winston Chamberlain, Michael F Chiang
Objective: Outpatient clinics lack guidance for tackling modern efficiency and productivity demands. Workflow studies require large amounts of timing data that are prohibitively expensive to collect through observation or tracking devices. Electronic health records (EHRs) contain a vast amount of timing data - timestamps collected during regular use - that can be mapped to workflow steps. This study validates using EHR timestamp data to predict outpatient ophthalmology clinic workflow timings at Oregon Health and Science University and demonstrates their usefulness in 3 different studies...
September 26, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29036345/phase-ii-study-of-cabozantinib-in-patients-with-progressive-glioblastoma-subset-analysis-of-patients-with-prior-antiangiogenic-therapy
#19
Timothy F Cloughesy, Jan Drappatz, John de Groot, Michael D Prados, David A Reardon, David Schiff, Marc Chamberlain, Tom Mikkelsen, Annick Desjardins, Jerry Ping, Jaymes Holland, Ron Weitzman, Patrick Y Wen
Background: Cabozantinib is a potent, multi-target inhibitor of hepatocyte growth factor receptor (MET) and vascular endothelial growth factor receptor-2 (VEGFR2). This open-label, phase II trial evaluated cabozantinib in patients with recurrent or progressive glioblastoma (GBM; NCT00704288). Methods: Patients were initially enrolled to a starting cabozantinib dose of 140 mg/day, but the starting dose was amended to 100 mg/day because of safety concerns. Treatment continued until disease progression or unacceptable toxicity...
October 3, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/29034588/clinical-and-demographic-differences-between-patients-with-manic-depressive-and-schizophrenia-spectrum-psychoses-presenting-to-early-intervention-services-in-london
#20
Adisha Kapila, Helen L Fisher, Sonia Johnson, Barnaby Major, Nikola Rahaman, John Joyce, Nick Chamberlain-Kent, Jo Lawrence, Allan H Young, James M Stone
AIM: To investigate the relationship between the presenting clinical and demographic characteristics in first-episode psychosis (FEP) patients with their clinical diagnostic grouping 1 year later. METHODS: Data from 1014 first-presentation psychosis patients from seven London-based Early Intervention Services were extracted from the MiData audit database. Associations between clinical and demographic measures at presentation and clinical diagnosis made at 1 year were assessed with analysis of variance (ANOVA) and Chi-square tests...
October 15, 2017: Early Intervention in Psychiatry
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