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https://www.readbyqxmd.com/read/28550633/the-efficiency-of-the-multi-walled-carbon-nanotubes-used-for-antibiotics-removal-from-wastewaters-generated-by-animal-farms
#1
Maria-Loredana Soran, Ocsana Opriş, Ildikó Lung, Irina Kacso, Alin S Porav, Manuela Stan
In the recent years, residual antibiotics are considered to be emerging environmental pollutants due to their continuous input and persistence into the aquatic ecosystem even at low concentrations. Therefore, these are necessary to develop efficient methods for the wastewater treatment. The present paper describes the efficiency of several types of multi-walled carbon nanotubes (MWCNTs) for the retention of the selected antibiotics (ampicillin, ceftazidime, cefepime, imipenem, piperacillin, tazobactam, tetracycline, erythromycin, ciprofloxacin, norfloxacin, vancomycin, gentamicin, sulfamethoxazole, and thrimetoprim) from aqueous (synthetic) solutions and wastewater samples...
May 27, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28549878/outbreak-of-imipenem-resistant-acinetobacter-baumannii-in-different-wards-at-a-regional-hospital-related-to-untrained-bedside-caregivers
#2
Ching-Hsun Wang, Jin-Feng Li, Li-Yueh Huang, Fu-Mei Lin, Ya-Sung Yang, L Kristopher Siu, Feng-Yee Chang, Jung-Chung Lin
BACKGROUND: This study describes an outbreak caused by imipenem-resistant Acinetobacter baumannii (IRAB) involving 2 general wards at the Penghu branch of Tri-Service General Hospital. METHODS: Clinical data obtained from the patients with IRAB during an outbreak from May 2014-October 2014 were reviewed. Microbiologic sampling from the environment and the hands of health care workers (HCWs) was performed. Clinical isolates from case patients were genotyped using pulsed-field gel electrophoresis (PFGE)...
May 23, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28545899/multiple-brain-abscesses-due-to-enterobacter-cloacae-in-an-immune-competent-child
#3
Arushi Gahlot Saini, Vinay Rathore, Chirag Kumar Ahuja, Rajesh Chhabra, Pankaj C Vaidya, Pratibha Singhi
Brain abscesses due to Enterobacteriaceae in immune-competent children are rare, and those due to Enterobacter cloacae are even rarer. We report an interesting case of community-acquired E. cloacae neuroinfection resulting in multiple brain abscesses in a young child with no underlying risk-factors. A 10 year-old-boy presented with low-grade fever, headache, neck pain and progressive deterioration of sensorium. On examination, he was conscious but drowsy with photophobia, normal fundii, meningeal signs, mild hypertonia, brisk muscle stretch reflexes and extensor plantar responses...
May 22, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28543519/a-new-treatment-of-sepsis-caused-by-veillonella-parvula-a-case-report-and-literature-review
#4
J Li, P Chen, J Li, X Gao, X Chen, J Chen
WHAT IS KNOWN AND OBJECTIVES: Veillonella parvula is usually regarded as a contaminant bacteria associated with polymicrobial infection. Here we report a rare case of sepsis caused by V. parvula, which was successfully treated by chloramphenicol. In addition, the therapeutic strategy for V. parvula infection was reviewed. CASE SUMMARY: A 55-year-old woman underwent surgery for lumbar spinal stenosis and developed high fever (39.5°C) after surgery, accompanied by chills and fatigue...
May 23, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28540775/preventing-intrahepatic-infection-after-ablation-of-liver-tumours-in-biliary-enteric-anastomosis-patients
#5
Shui-Lian Tan, Xiao-Ling Yu, Ping Liang, Fangyi Liu, Zhigang Cheng, Zhi-Yu Han, Jie Yu
PURPOSE: To assess the value of bowel preparation plus targeted antibiotics for preventing intrahepatic infections after MWA of liver tumours in BEA patients. MATERIALS AND METHODS: This retrospective study included 21 patients (divided into two groups) with a history of BEA undergoing ultrasound-guided MWA of liver tumours from November 2008 to June 2014. Group A (n = 10) received single-antibiotic therapy (cefazedone 2 g bid 4, amoxicillin and flucloxacillin sodium 2 g bid 3, levofloxacin 0...
February 28, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540747/in-vitro-susceptibility-and-resistance-phenotypes-in-contemporary-enterobacter-isolates-in-a-university-hospital-in-crete-greece
#6
Sofia Maraki, Konstantinos Z Vardakas, George Samonis, Dimitrios Perdikis, Viktoria Eirini Mavromanolaki, Diamantis P Kofteridis, Matthew E Falagas
AIM: To study the evolution in the susceptibility of Enterobacter spp. in Crete, Greece from 2010 to 2015. METHODS: Non-duplicate isolates were studied using automated systems. Phenotypic confirmatory tests were applied. RESULTS: A total of 939 Enterobacter isolates were included. Colistin was the most active antibiotic (97.9%) followed by imipenem (96.1%), gentamicin (95.7%), tigecycline (91.8%), cefepime (89.4%), chloramphenicol (85.8%), fosfomycin (85...
May 25, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28537050/prevalence-and-significance-of-fluoroquinolone-resistant-bacteria-carriage-in-patients-undergoing-transrectal-ultrasound-prostate-biopsy
#7
Amir Hasanzadeh, Mohammad Reza Pourmand, Ahad Alizadeh, Gholamreza Pourmand
PURPOSE: To determine the prevalence of fluoroquinolone-resistant (FQR) bacteria carriage in patients undergoing transrectal ultrasound prostate biopsy (TRUS-Bx), and the relationship between the risk factors and FQR carriers as well as infections after prostate biopsy. MATERIALS AND METHODS: Rectal swabs were obtained from 158 patients undergoing TRUS-Bx. The FQR organisms were isolated using selective media, and the antibiotic susceptibility pattern was determined...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28535440/management-of-ventilator-associated-pneumonia-with-a-new-antibiotic-adjuvant-entity-ceftriaxone-sulbactam-disodium-edetate-a-novel-approach-to-spare-carbapenems
#8
Prachee Sathe, Sagar Maddani, Shilpa Kulkarni, Nita Munshi
BACKGROUND: Ventilator associated pneumonia (VAP) is one of the most serious nosocomial infections in Intensive Care Unit (ICU). The aim of this study was to evaluate a new approach to spare the carbapenems for the management of patients diagnosed with VAP due to Acinetobacter baumannii (A. baumannii). METHOD: This retrospective study was conducted on VAP patients presenting for treatment at tertiary care centre between May 2014 and March 2016. The case sheets of patients who have been treated for VAP with meropenem, antibiotic adjuvant entity (AAE) and colistin were analysed...
May 15, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28535303/a-novel-goldnano-carb-test-for-rapid-phenotypic-detection-of-carbapenemases-particularly-oxa-type-in-enterobacteriaceae-pseudomonas-aeruginosa-and-acinetobacter-spp
#9
Arpasiri Srisrattakarn, Aroonlug Lulitanond, Chotechana Wilailuckana, Nicha Charoensri, Jureerut Daduang, Aroonwadee Chanawong
Objectives: To develop a simple gold nanoparticle (AuNP)-based colorimetric test, GoldNano Carb (GoldC), for detecting carbapenemase production in Gram-negative bacteria, compared with updated Carba NP (CNP) and CarbAcineto NP (CAcNP) tests by using PCR methods as gold standard. Methods: Ninety-nine carbapenemase-producing Enterobacteriaceae (CPE), Pseudomonas spp. and Acinetobacter spp. isolates and 89 non-CPE isolates were tested by the GoldC and CNP. Additionally, the CAcNP was performed in the Acinetobacter spp...
May 23, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28535274/development-of-carbapenem-resistance-in-pseudomonas-aeruginosa-is-associated-with-oprd-polymorphisms-particularly-the-amino-acid-substitution-at-codon-170
#10
Jwu-Ching Shu, An-Jing Kuo, Lin-Hui Su, Tsui-Ping Liu, Ming-Hsun Lee, I-Ning Su, Tsu-Lan Wu
Objectives: Pan-susceptible Pseudomonas aeruginosa (PSPA) clinical isolates carrying an OprD with loop 7 shortening (the group-1A allele) were found to rapidly develop carbapenem resistance under continuous selection pressure. We further studied whether OprD polymorphisms are associated with the potential to develop carbapenem resistance. Methods: OprD amino acid sequences of 126 PSPA clinical isolates were analysed to determine their STs using P. aeruginosa strain PAO1 as the control strain...
May 23, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28533769/celecoxib-enhances-the-efficacy-of-low-dose-antibiotic-treatment-against-polymicrobial-sepsis-in-mice-and-clinical-isolates-of-eskape-pathogens
#11
Madhavi Annamanedi, Gajapati Y N Varma, K Anuradha, Arunasree M Kalle
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the minimal inhibitory concentration to limit Staphylococcus aureus infection. However, the efficacy of this combinatorial treatment against various pathogenic bacteria is not determined. Therefore, we have evaluated the potential use of celecoxib in combination with low doses of antibiotic in limiting Gram-positive and Gram-negative bacteria in vivo in murine polymicrobial sepsis developed by cecum ligation and puncture (CLP) method and against clinically isolated human ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28528936/efficacy-of-non-carbapenem-antibiotics-for-pediatric-patients-with-first-febrile-urinary-tract-infection-due-to-extended-spectrum-beta-lactamase-producing-escherichia-coli
#12
Yoshifusa Abe, Işil Inan-Erdogan, Kunihiko Fukuchi, Hitomi Wakabayashi, Yasuha Ogawa, Satoshi Hibino, Shunsuke Sakurai, Kazuhiko Matsuhashi, Yoshitaka Watanabe, Kaori Hashimoto, Kazuhisa Ugajin, Kazuo Itabashi
Although carbapenem is the recommended for urinary tract infection (UTI) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms, non-carbapenems have been reported to be effective for adult patients with UTI caused by ESBL-producing organisms. The purpose of this study was to evaluate the efficacy of non-carbapenems for pediatric patients with UTI due to ESBL-producing Escherichia coli (E. coli) based on the microbiologic and clinical outcomes. Fifteen children, who were treated for first febrile UTI caused by ESBL-producing E...
May 18, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28511383/study-on-mics-of-tigecycline-in-clinical-isolates-of-carbapenem-resistant-enterobacteriaceae-cre-at-a-tertiary-care-centre-in-north-india
#13
Vineeta Khare, Prashant Gupta, Fareya Haider, Rehana Begum
INTRODUCTION: Members of family Enterobacteriaceae are the most common Gram-negative bacteria isolated from clinical samples. Those Enterobacteriaceae which have acquired resistance to all β-lactams antibiotics including the carbapenems are considered as Carbapenem Resistant Enterobacteriaceae (CRE). These CRE isolates are often resistant to most other classes of antimicrobials as well, making their treatment a great challenge. Tigecycline is one of the last resort antimicrobials against such multidrug resistant bacteria...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28506633/-anaerobiospirillum-succiniciproducens-and-desulfovibrio-desulfuricans-in-2-cases-of-insidious-bacteremia
#14
Silvia C Predari, Adriana N de Paulis, Eugenia Bertona, Daiana Guevara Núñez, Juan P Suárez, Liliana Castello
Two cases of insidious bacteremia by uncommon curve and spiral-shaped, motile anaerobic gram-negative rods are presented. Both of them were of an unclear origin and occurred in immunosuppressed patients with simultaneous diseases. The key tests for the identification of Anaerobiospirillum were its micromorphology, a strictly anaerobic condition, negative catalase activity, the special-potency disk profile, glucose fermentation, and β-NAG production. Desulfovibrio species was identified by all the above preliminary tests but with a different disk profile, as well as for being asaccharolytic and desulfoviridin and H2S producer...
May 12, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28506272/prevalence-and-clonal-relationship-of-esbl-producing-salmonella-strains-from-humans-and-poultry-in-northeastern-algeria
#15
Samia Djeffal, Sofiane Bakour, Bakir Mamache, Rachid Elgroud, Amir Agabou, Selma Chabou, Sana Hireche, Omar Bouaziz, Kheira Rahal, Jean-Marc Rolain
BACKGROUND: The aims of this study were to investigate Salmonella contamination in broiler chicken farms and slaughterhouses, to assess the antibiotic resistance profile in avian and human Salmonella isolates, and to evaluate the relationship between avian and human Extended Spectrum β-Lactamase (ESBL)-producing isolates. Salmonella was screened in different sample matrices collected at thirty-two chicken farms and five slaughterhouses. The human isolates were recovered from clinical specimens at the University Teaching Hospital of Constantine (UTH)...
May 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28499958/unexpected-persistence-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-in-the-faecal-microbiota-of-hospitalised-patients-treated-with-imipenem
#16
N Grall, V Lazarevic, N Gaïa, C Couffignal, C Laouénan, E Ilic-Habensus, I Wieder, P Plesiat, C Angebault, M E Bougnoux, L Armand-Lefevre, A Andremont, X Duval, J Schrenzel
Imipenem is active against extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) but favours the intestinal emergence of resistance. The effects of imipenem on intestinal microbiota have been studied using culture-based techniques. In this study, the effects were investigated in patients using culture and metagenomic techniques. Seventeen hospitalised adults receiving imipenem were included in a multicentre study (NCT01703299, http://www.clinicaltrials.gov). Most patients had a history of antibiotic use and/or hospitalisation...
May 9, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28497052/etiological-and-resistance-profile-of-bacteria-involved-in-urinary-tract-infections-in-young-children
#17
Antonio Sorlózano-Puerto, José María Gómez-Luque, Juan de Dios Luna-Del-Castillo, José María Navarro-Marí, José Gutiérrez-Fernández
Background. The objective of this study was to identify the bacteria most frequently responsible for urinary tract infection (UTI) in the population of under-2-year-olds in our geographic area and to evaluate the activity of antibiotics widely used for UTI treatment during a 4-year study period. Materials and Methods. A retrospective analysis was conducted of data on the identification and susceptibility of microorganisms isolated in urine samples from children under 2 years of age. Results. A total of 1,045 uropathogens were isolated...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28486994/the-emergence-of-a-novel-sequence-type-of-mdr-acinetobacter-baumannii-from-the-intensive-care-unit-of-an-egyptian-tertiary-care-hospital
#18
Doaa Mohammad Ghaith, Mai Mahmoud Zafer, Mohamed Hamed Al-Agamy, Essam J Alyamani, Rayan Y Booq, Omar Almoazzamy
BACKGROUND AND AIM OF WORK: Acinetobacter baumannii is known for nosocomial outbreaks worldwide. In this study, we aimed to investigate the antibiotic susceptibility patterns and the clonal relationship of A. baumannii isolates from the intensive care unit (ICU) of an Egyptian hospital. METHODS: In the present study, 50 clinical isolates of multidrug resistant (MDR)-A. baumannii were obtained from patients admitted into the ICU from June to December 2015. All isolates were analyzed for antimicrobial susceptibilities...
May 10, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28480928/differential-flap-dynamics-in-l-d-transpeptidase2-from-mycobacterium-tuberculosis-revealed-by-molecular-dynamics
#19
Zeynab Fakhar, Thavendran Govender, Glenn E M Maguire, Gyanu Lamichhane, Ross C Walker, Hendrik G Kruger, Bahareh Honarparvar
Despite the advances in tuberculosis treatment, TB is still one the most deadly infectious diseases and remains a major global health quandary. Mycobacterium tuberculosis (Mtb) is the only known mycobacterium with a high content of 3→3 crosslinks in the biosynthesis of peptidoglycan, which is negligible in most bacterial species. An Mtb lacking LdtMt2 leads to alteration of the colony morphology and loss of virulence which makes this enzyme an attractive target. Regardless of the vital role of LdtMt2 for cell wall survival, the impact of ligand binding on the dynamics of the β-hairpin flap is still unknown...
May 8, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/28480813/risk-factors-associated-with-multi-drug-resistant-acinetobacter-baumannii-nosocomial-infections-at-a-tertiary-care-hospital-in-makkah-saudi-arabia%C3%A2-%C3%A2-a-matched-case-control-study
#20
Manal M Al-Gethamy, Hani S Faidah, Hamed A Ademola, Abdul Haseeb, Sami S Ashgar, Tayeb K Mohanned, Al-Haj Mohammed, Muhammad Khurram, Mohamed A Hassali
Objective To determine risk factors for multi-drug-resistant Acinetobacter baumannii (MDR-AB) nosocomial infections in intensive care units in a tertiary care hospital, Makkah, Saudi Arabia. Methods We performed a hospital-based, matched case-control study in patients who were admitted to Al Noor Specialist Hospital between 1 January 2012 and 31 August 2012. The study included cases of A. baumannii nosocomial infection and controls without infection. Controls were matched to cases by age and ward of admission...
January 1, 2017: Journal of International Medical Research
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