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https://www.readbyqxmd.com/read/29690929/gonococcal-sepsis-in-a-32-year-old-female-a-case-report
#1
Michael Owusu, Kwadwo Sarfo Marfo, Godfred Acheampong, Abednego Arthur, Nimako Sarpong, Justin Im, Ondari D Mogeni, Augustina Annan, Hsin-Ying Chiang, Chih-Horng Kuo, Se Eun Park, Florian Marks, Ellis Owusu-Dabo, Yaw Adu-Sarkodie
BACKGROUND: Neisseria gonorrhoeae is a Gram-negative bacterium which affects the urethra, throat, rectum and cervix of patients and often associated with sexually transmitted infections. The global epidemiology of the disease is not well characterised especially in resource constraint countries due to poor diagnostic capacity and inefficient reporting systems. Although important, little is known about the propensity of this bacterium to cause sepsis in immunocompetent individuals. CASE PRESENTATION: A 32-year-old female presented with fever and generalised malaise to a rural hospital in Ghana...
April 24, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29686708/association-between-prior-chlamydia-trachomatis-infection-and-ectopic-pregnancy-at-a-tertiary-care-hospital-in-south-western-uganda
#2
Derrick Paul Mpiima, George Wasswa Salongo, Henry Lugobe, Augustine Ssemujju, Olivier Mumbere Mulisya, Abraham Masinda, Hillary Twizerimana, Joseph Ngonzi
Background: Increase in the number of ectopic pregnancy is attributed to increase in the incidence of pelvic infections. Chlamydia trachomatis is responsible for most of the sexually transmitted bacterial infections. If undetected and untreated, the infection can ascend to the upper genital tract and cause pelvic inflammatory disease (PID) and related sequelae (ectopic pregnancy and tubal factor infertility). Objective: To determine the association between prior Chlamydia trachomatis infection and ectopic pregnancy at Mbarara Regional Referral Hospital (MRRH)...
2018: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/29680458/sexually-transmitted-diseases-of-the-anus-and-rectum-causal-agents-coinfections-hiv-infection-and-high-risk-sexual-behaviour
#3
Daniel Morgado-Carrasco, Mercè Alsina Gibert, Jordi Bosch Mestres, Miriam Álvarez Martínez, José Luís Blanco Arévalo, Irene Fuertes de Vega
INTRODUCTION AND OBJECTIVE: Sexually transmitted infections of the rectum and anus (STI-RA) mainly affect men who have sex with men (MSM). The incidence of STI-RA among them has increased in recent years. MATERIAL AND METHODS: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Epidemiological, clinical and microbiological data were collected. RESULTS: We included 95 patients, all of whom were MSM; 88...
April 18, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29680200/biological-feasibility-and-importance-of-a-gonorrhea-vaccine-for-global-public-health
#4
Leah R Vincent, Ann E Jerse
There is a growing public health interest in controlling sexually transmitted infections (STIs) through vaccination due to increasing recognition of the global disease burden of STIs and the role of STIs in women's reproductive health, adverse pregnancy outcomes, and the health and well-being of neonates. Neisseria gonorrhoeae has historically challenged vaccine development through the expression of phase and antigenically variable surface molecules and its capacity to cause repeated infections without inducing protective immunity...
April 18, 2018: Vaccine
https://www.readbyqxmd.com/read/29670527/comparative-metabolomics-analysis-of-cervicitis-in-human-patients-and-a-phenol-mucilage-induced-rat-model-using-liquid-chromatography-tandem-mass-spectrometry
#5
Xiaoyong Zhang, Junmao Li, Bin Xie, Bei Wu, Shuangxia Lei, Yun Yao, Mingzhen He, Hui Ouyang, Yulin Feng, Wen Xu, Shilin Yang
Cervicitis is an exceedingly common gynecological disorder that puts women at high risk of sexually transmitted infections and induces a series of reproductive system diseases. This condition also has a significant impact on quality of life and is commonly misdiagnosed in clinical practice due to its complicated pathogenesis. In the present study, we performed non-targeted plasma metabolomics analysis of cervicitis in both plasma samples obtained from human patients and plasma samples from a phenol mucilage induced rat model of cervicitis, using ultra-performance liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29658200/detection-of-ureaplasma-species-by-a-semi-quantitative-pcr-test-in-urine-samples-can-it-predict-clinical-significance
#6
Merav Strauss, Raul Colodner, Dana Sagas, Azmi Adawi, Hanna Edelstein, Bibiana Chazan
BACKGROUND: Ureaplasma species (Usp) are the most prevalent genital Mycoplasma isolated from the urogenital tract of both men and women. Usp may be commensals in the genital tract but may also be contributors to a number of pathological conditions of the genital tract. Because they can also just colonize the genital tract of healthy people, their pathogenic role can be difficult to prove. OBJECTIVES: The aim of the study was to evaluate the efficacy of a quantitative polymerase chain reaction (qPCR) method for the discrimination between infection and colonization by measuring prevalence of Usp in asymptomatic versus symptomatic patients...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29656416/women-infected-with-hiv-and-the-impact-of-associated-sexually-transmitted-infections
#7
REVIEW
Somaia Reda, Fernanda Aguiar Gonçalves, Melissa Mello Mazepa, Newton Sérgio de Carvalho
OBJECTIVE: To review the relationship between concomitant sexually transmitted infections in women infected with HIV. METHODS: PubMed and Scopus were searched for articles published in English and Portuguese between January 1, 1994, and December 31, 2015, using relevant keywords, including AIDS, HIV, female genital diseases, and sexually transmitted infections. Articles that associated sexually transmitted infections with HIV-infected women were selected for inclusion...
April 14, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29648649/infectious-inflammatory-and-autoimmune-male-factor-infertility-how-do-rodent-models-inform-clinical-practice
#8
Monika Fijak, Adrian Pilatz, Mark P Hedger, Nour Nicolas, Sudhanshu Bhushan, Vera Michel, Kenneth S K Tung, Hans-Christian Schuppe, Andreas Meinhardt
BACKGROUND: Infection and inflammation of the reproductive tract are significant causes of male factor infertility. Ascending infections caused by sexually transmitted bacteria or urinary tract pathogens represent the most frequent aetiology of epididymo-orchitis, but viral, haematogenous dissemination is also a contributory factor. Limitations in adequate diagnosis and therapy reflect an obvious need for further understanding of human epididymal and testicular immunopathologies and their contribution to infertility...
April 10, 2018: Human Reproduction Update
https://www.readbyqxmd.com/read/29648594/active-case-finding-for-communicable-diseases-in-prison-settings-increasing-testing-coverage-and-uptake-among-the-prison-population-in-the-european-union-european-economic-area
#9
Lara Tavoschi, Hilde Vroling, Giordano Madeddu, Sergio Babudieri, Roberto Monarca, Marije Vonk Noordegraaf-Schouten, Netta Beer, Joana Gomes Dias, Éamonn O'Moore, Dagmar Hedrich, Anouk Oordt-Speets
Prison populations are disproportionally affected by communicable diseases when compared with the general community because of a complex mix of socioeconomic determinants and environmental factors. Tailored and adequate health care provision in prisons has the potential to reach vulnerable and underserved groups and address their complex needs. We investigated the available evidence on modalities and effectiveness of active case-finding interventions in prisons by searching PubMed, Embase, and the Cochrane Library for records on prison and active case finding with no language limit...
April 10, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29644437/a-paperfluidic-platform-to-detect-neisseria-gonorrhoeae-in-clinical-samples
#10
Audrey L Horst, Justin M Rosenbohm, Nikunja Kolluri, Justin Hardick, Charlotte A Gaydos, Mario Cabodi, Catherine M Klapperich, Jacqueline C Linnes
Globally, the microbe Neisseria gonorrhoeae (NG) causes 106 million newly documented sexually transmitted infections each year. Once appropriately diagnosed, NG infections can be readily treated with antibiotics, but high-risk patients often do not return to the clinic for treatment if results are not provided at the point of care. A rapid, sensitive molecular diagnostic would help increase NG treatment and reduce the prevalence of this sexually transmitted disease. Here, we report on the design and development of a rapid, highly sensitive, paperfluidic device for point-of-care diagnosis of NG...
April 11, 2018: Biomedical Microdevices
https://www.readbyqxmd.com/read/29644039/giant-anorectal-condyloma-acuminatum-of-buschke-l%C3%A3-wenstein-presents-difficult-management-decisions
#11
Hyunyoung G Kim, Jennifer E Kesey, John A Griswold
Condyloma acuminata, or anogenital warts, caused by human papillomavirus are the most common sexually transmitted disease. In rare cases, the disease could progress to an extensive neoplasm called Buschke-Löwenstein tumor (BLT), also known as giant condyloma acuminatum. BLT differs from normal condyloma acuminata by presenting with locally invasive growth, lack of spontaneous resolution, tendency for recurrence after treatment and potential for malignant transformation. We examine a BLT case reaching large dimensions in the anorectal region treated with neoadjuvant chemoradiation therapy and surgical excision of residual lesions...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29627410/-intrauterine-device-and-pelvic-inflammatory-disease-myth-or-reality
#12
T Straub, M Reynaud, M Yaron
INTRODUCTION: Intrauterine device (IUD) is a reliable contraceptive method that is long term reversible, and well tolerated. Numerous studies prove its efficiency and report rare complications that are attributed to it. However, its use is limited due to fear that it can cause a pelvic inflammatory disease (PID). This is based on historical data on infections related to the "Dalkon Shield", which was removed from the market in 1974. METHOD: The analyzed articles were extracted from PUBMED database between 2000 and 2016...
April 4, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29624561/recent-changes-in-prevention-funding-to-areas-with-high-racial-and-ethnic-disparities-in-sexually-transmitted-disease-rates
#13
Austin Williams, Harrell Chesson
We examined changes in federal STD funding allocations to areas with high racial/ethnic disparities in STDs following the implementation of a funding formula in 2014. The funding formula increased prevention funding allocations to areas with high relative racial/ethnic disparities. Results were mixed for areas with high absolute disparities.
April 5, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29623213/a-case-of-oropharyngeal-ureaplasma-urealyticum-infection-in-a-human-immunodeficiency-virus-positive-bisexual-male-co-infected-with-human-papilloma-virus-and-treponema-pallidum
#14
Nazneen Arif Suri, Sujeesh Sebastian, Deepika Yadav, Neena Khanna, Benu Dhawan
Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address Neisseria gonorrhoeae and Chlamydia trachomatis alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites. Case presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts...
March 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29619908/prevalence-of-sexually-transmitted-diseases-in-asymptomatic-renal-transplant-recipients
#15
Mehmet Sarier, Nevgun Sepin Ozen, Hicran Guler, Ibrahim Duman, Yücel Yüksel, Sabri Tekin, Asuman Havva Yavuz, Levent Yucetin, Mine Erdogan Yilmaz
OBJECTIVES: Sexually transmitted diseases, which may be asymptomatic, have the potential to cause serious health problems in renal transplant recipients. The aim of this study was to determine the prevalence of sexually transmitted diseases in sexually active asymptomatic renal transplant patients by using real-time multiplex polymerase chain reaction assays. MATERIALS AND METHODS: This prospective controlled study was conducted between November 2016 and January 2017 in our hospital...
April 4, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29619436/concomitant-sexually-transmitted-diseases-in-patients-with-diagnosed-hiv-aids-a-retrospective-study
#16
Densy Violina Harnanti, Afif Nurul Hidayati, Muhammad Miftahussurur
Background: Human immunodeficiency virus (HIV) is a virus that causes Acquired Immunodeficiency Syndrome (AIDS) which weaken the human immune system and thus increasing the incidence of sexually transmitted infections (STIs) and vice versa. Materials and Methods: A retrospective study of STIs in HIV/AIDS patients in Unit Perawatan Intermediate Penyakit Infeksi (UPIPI) Dr. Soetomo General Hospital Surabaya was conducted from January 1st, 2013 to December 31st, 2014...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29616284/-urology-and-alternative-medicine-1900-1970
#17
REVIEW
F G Mildenberger
Disorders of the lower abdomen were often associated with sexually transmitted diseases (STDs) or related conditions. The urological diagnostic workup and treatment was based on the idea that technical devices and objective scientific examination methods would lead to targeted success. The fact that illnesses such as urinary retention, urinary incontinence, urge incontinence, orchitis or urethritis often implicated psychosomatic complications and had a possibly far more important impact on sexual life did not play a role in the early years of urology...
April 3, 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29615297/is-there-synergy-in-syndemics-psychosocial-conditions-and-sexual-risk-among-men-who-have-sex-with-men-in-india
#18
Cecilia Tomori, Allison M McFall, Sunil S Solomon, Aylur K Srikrishnan, Santhanam Anand, P Balakrishnan, Shruti H Mehta, David D Celentano
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Following these suggestions, we compared the traditional additive approach with a test for synergistic association of 5 syndemic conditions (alcohol dependence, illicit drug use, depression, intimate partner violence (IPV), and childhood sexual abuse (CSA)) with unprotected anal intercourse (UAI) and active syphilis infection among 11,771 MSM recruited through respondent driven sampling from 12 cities in India...
March 23, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29610589/a-statistical-assessment-of-information-knowledge-and-attitudes-of-medical-students-regarding-contraception-use
#19
Anca A Simionescu, Alexandra Horobet, Lucian Belascu
Objective: To evaluate how contraception use is linked to information, knowledge and attitudes towards family planning and contraception of medical students. Methods: This is a voluntary cross-sectional study using an anonymous questionnaire applied to 62 medical students. The questionnaire had the following main structure: characteristics of the studied population, information on contraception, knowledge about contraception methods, attitudes regarding family planning and contraception, and contraception use...
December 2017: Mædica
https://www.readbyqxmd.com/read/29607650/factors-associated-with-high-grade-anal-intraepithelial-lesion-in-hiv-positive-men-in-a-southern-u-s-city
#20
Melanie Ann Frank, Cecile Lahiri, Minh Ly Nguyen, C Christina Mehta, Marina Mosunjac, Lisa Flowers
The incidence of anal cancer is increased in HIV-infected patients compared to the general population. Risk factors associated with the anal cancer precursor, high-grade squamous intraepithelial lesion (HSIL), have not been extensively studied in an urban black population with late stage HIV disease. We performed a retrospective chart review of HIV infected men at the Grady Ponce de Leon Center HIV Clinic in Atlanta, Georgia referred for high resolution anoscopy (HRA), a procedure where anal tissue is examined under magnification and abnormal areas are biopsied...
April 1, 2018: AIDS Research and Human Retroviruses
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