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https://www.readbyqxmd.com/read/29222644/membrane-shed-vesicles-from-the-parasite-trichomonas-vaginalis-characterization-and-their-association-with-cell-interaction
#1
Yesica R Nievas, Veronica M Coceres, Victor Midlej, Wanderley de Souza, Marlene Benchimol, Antonio Pereira-Neves, Ajay A Vashisht, James A Wohlschlegel, Patricia J Johnson, Natalia de Miguel
Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human urogenital tract, where it remains extracellular and adheres to epithelial cells. Infections range from asymptomatic to highly inflammatory, depending on the host and the parasite strain. Despite the serious consequences associated with trichomoniasis disease, little is known about parasite or host factors involved in attachment of the parasite-to-host epithelial cells. Here, we report the identification of microvesicle-like structures (MVs) released by T...
December 8, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29221651/-the-myth-of-virgin-cleansing-latest-news-on-an-archaic-magico-religious-practice
#2
P Charlier, F Bou Abdallah, L Brun, V Hoang-Oppermann, S Deo, Y Mostefai-Dulac, M-F Mamzer, C Hervé
BACKGROUND: In the medical anthropology section of the Nanterre Hospital (France) for migrants and refugees, three cases were recorded of "virgin cleansing" in sub-Saharan African countries. PATIENTS AND METHODS: These consisted of sexual assaults (2 instances of rape and 1 of sexual interference) on sexually immature females (young girls) by patients with sexually transmitted infections (mainly HIV, syphilis) hoping they might thereby be cured. DISCUSSION: These particularly atrocious hetero-aggressive sexual practices based on magical arguments are unfortunately universal and are not limited to a specific culture...
December 5, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29220710/life-satisfaction-and-its-associated-factors-among-money-boys-in-china
#3
A Zhang, J Yan, G Yang, X Tan, X Wang, S Tan
OBJECTIVES: Money Boy (MB) is a unique term used in China referring to a specialized population of men who sell sex to other men. Life satisfaction can influence one's health-related behaviors. The aim of our study was to find out the situation of MBs' life satisfaction and its associated factors. STUDY DESIGN: A cross-sectional study among MBs was conducted between July and December 2013 in Hunan province, China. METHODS: Respondent-driven sampling method was used for recruitment, with the initial seven 'seeds' found from a gay dating website, and 234 participants were enrolled into the study...
December 5, 2017: Public Health
https://www.readbyqxmd.com/read/29219803/accuracy-and-reproducibility-of-the-etest-to-detect-drug-resistant-neisseria-gonorrhoeae-to-contemporary-treatment
#4
John R Papp, Marie-Claire Rowlinson, Norman P O'Connor, Jason Wholehan, Jafar H Razeq, Anita Glennen, Dapne Ware, Peter C Iwen, Lillian V Lee, Celia Hagan
PURPOSE: Neisseria gonorrhoeae is a sexually transmitted bacterial pathogen that continues to evolve to become resistant to known antibiotics. In preparing for potential emergence, the Centers for Disease Control and Prevention recommends that clinical laboratories maintain or develop protocols to assess antibiotic susceptibly for this organism. This study examines the intra-laboratory variability of using the Etest method to provide consistent MIC values for N. gonorrhoeae and also compared the results of the Etest to known agar dilution MIC values...
December 8, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29216562/substituted-carbamothioic-amine-1-carbothioic-thioanhydrides-as-novel-trichomonicidal-fungicides-design-synthesis-and-biology
#5
Dhanaraju Mandalapu, Bhavana Kushwaha, Sonal Gupta, Shagun Krishna, Nidhi Srivastava, Mahendra Shukla, Pratiksha Singh, Bhavana S Chauhan, Ravi Goyani, Jagdamba P Maikhuri, Koneni V Sashidhara, Brijesh Kumar, Renu Tripathi, Praveen K Shukla, Mohammad I Siddiqi, Jawahar Lal, Gopal Gupta, Vishnu L Sharma
Sexually transmitted diseases like trichomoniasis along with opportunistic fungal infections like candidiasis are major global health burden in female reproductive health. In this context a novel non-nitroimidazole class of substituted carbamothioic amine-1-carbothioic thioanhydride series was designed, synthesized, evaluated for trichomonacidal and fungicidal activities, and was found to be more active than the standard drug Metronidazole (MTZ). Compounds were trichomonicidal in the MIC ranges of 4.77-294...
November 23, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29215133/a-five-year-retrospective-study-on-syphilis-in-the-sexual-transmitted-disease-centre-stdc-of-the-teaching-hospital-umberto-i-in-rome
#6
S Pala, C Conti, P Goldoni, D Silvaggio, M Nicolai, E Schiariti, G B Orsi
OBJECTIVES: A retrospective study describing syphilis epidemiological and clinical features in patients referring to an infectious diseases centre in Rome, Italy. METHODS: Between January 2011 and December 2015 demographic, behavioral and clinical data were collected from all adult patients attending the Sexually Transmitted Diseases Centre of the Teaching Hospital Umberto I in Rome. RESULTS: Overall 723 patients, 495 males and 228 females, with syphilis infection diagnosis were included...
January 2018: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29209789/-novel-aspects-of-the-guidelines-for-hemotherapy-2017-implications-for-anesthesiology
#7
REVIEW
I Pekrul, G Wittmann, P Möhnle
Based on the German Transfusion Law, the periodically updated guidelines "Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten" ("Hämotherapierichtlinien") are intended to provide the current knowledge and state of the art of blood transfusion practice in Germany. The novel update 2017 contains relevant changes for blood donation, especially the extension of the exclusion period of persons at risk for sexually transmitted HBV, HCV and HIV diseases to 12 months. Moreover, the guidelines provide several changes relevant to blood transfusion practice in anesthesiology, such as: all autologous hemotherapy procedures including normovolemic hemodilution, cell saver, and autologous blood donation and transfusion require formal registration at the regulatory authority...
December 5, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29209488/education-early-screening-and-treatment-of-stis-could-reduce-infertility-among-women-in-kenya
#8
EDITORIAL
S M Musundi
In Kenya, sexually transmitted infections (STIs) such as Chlamydia trachomatis, Neisseria gonorrhoea, HIV, herpes simplex virus type 2 (HSV-2), syphilis and trichomoniasis tend to be prevalent, especially in women. Further, the research shows that women who test positive for STIs (other than HIV), have little knowledge of these infections. Of particular concern, is that there has been little attention on the part of government to educate the general public about STIs, yet these diseases can have devastating consequences on women's and men's health...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29208879/oncoe6-positivity-among-via-positive-suspected-cases-from-colposcopy-clinic-of-mymensingh-medical-college-hospital-mymensingh
#9
F Nahar, M A Hossain, S K Paul, M U Ahmed, S Khatun, N Akhter, G R Bhuiyan, S A Nasreen, S Roy, T K Barman, N Laskar, H Begum, S Abedin, N Haque, S Ahmed, N Kobayashi
Cervical cancer is a major world health problem for women. It is the fourth most leading cause of death in women around the world. High risk HPV DNA has been shown to be present in 99.7% of cervical cancers worldwide. Oncoprotein E6 and E7 play an important role in the development of cervical cancer which can be detected by OncoE6 cervical test. This Cross sectional observational study was performed to detect E6 Oncoprotein from cervical swab by OncoE6 cervical test. Following universal safety precautions a total of 47 endocervical swabs were collected from Colposcopy clinic of Obstetrics and Gynaecology department of Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from January 2015 to December 2015...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29203273/the-traditional-use-of-vachellia-nilotica-for-sexually-transmitted-diseases-is-substantiated-by-the-antiviral-activity-of-its-bark-extract-against-sexually-transmitted-viruses
#10
Manuela Donalisio, Valeria Cagno, Andrea Civra, Davide Gibellini, Giuseppina Musumeci, Massimo Rittà, Manik Ghosh, David Lembo
ETHNOPHARMACOLOGICAL RELEVANCE: Vachellia (Acacia) nilotica and other plants of this genus have been used in traditional medicine of Asian and African countries to treat many disorders, including sexually transmitted diseases, but few studies were performed to validate their anti-microbial and anti-viral activity against sexually transmitted infections. AIM OF THE STUDY: The present study was undertaken to explore whether the ethnomedical use of V.nilotica to treat genital lesions is substantiated by its antiviral activity against the human immunodeficiency virus (HIV), the herpes simplex virus (HSV) and the human papillomavirus (HPV)...
December 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29202553/extramammary-paget-s-disease-associated-with-genital-wart-and-lichen-sclerosus
#11
Rana Rafiei, Hojat Eftekhari, Siamak Granmayeh, Nahid Nickhah, Behnam Rafiee
Extramammary Paget's disease is an uncommon intraepithelial adenocarcinoma in genital and perianal regions. Genital wart is the most common sexually transmitted disease caused by human papilloma viruses and vulval lichen sclerosus is chronic pruritic dermatitis in genital area which could be able to change to invasive squamous cell carcinoma. We report a patient who had simultaneous lichen sclerosus, genital wart and extramammary Paget's disease of the vulva. We could not find any significant association between them in literature...
September 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29201473/recurrent-huge-left-bartholin-s-gland-abscess-for-one-year-in-a-teenager
#12
Athanase Lilungulu, Bonaventura C T Mpondo, Abdallah Mlwati, Dismas Matovelo, Albert Kihunrwa, Balthazar Gumodoka
Bartholin's gland abscess is the commonest worldwide reported abscess in gynaecological outpatient clinics; it has also been reported that Bartholin's gland abscess is three times more common in occurrences compared to Bartholin's gland cyst. It is more common in women who are at risk of acquiring sexually transmitted infections; however, other causes of infection should be investigated to exclude other causes of disease. We present the case of an 18-year-old female patient, a teenager of the reproductive age group, with the recurrent development of huge Bartholin's gland abscess in a period of one year...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29201420/knowledge-acceptance-and-utilisation-of-the-female-condom-among-women-of-reproductive-age-in-ghana
#13
Mark Kwame Ananga, Nuworza Kugbey, Jemima Misornu Akporlu, Kwaku Oppong Asante
Background: The female condom (FC) is the only safe and effective female-initiated method that provides simultaneous protection against unintended pregnancy as well as sexually transmitted infections (STIs), including HIV/AIDS. Knowledge of FC use among women and the perceptions and attitudes towards condom use can contribute to its uptake as an important public health strategy for HIV prevention in Ghana. However, there is a dearth of empirical evidence in this area of public health research to inform interventions...
2017: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29195636/attitudes-of-physicians-providing-family-planning-services-in-egypt-about-recommending-intrauterine-device-for-family-planning-clients
#14
Mirette Aziz, Sabra Ahmed, Boshra Ahmed
OBJECTIVES: To assess the attitudes of physicians providing family planning services at the public sector in Egypt about recommending intrauterine device (IUD) for family planning clients, and to identify the factors that could affect their attitudes. METHODS: A descriptive cross sectional study, in which all the physicians providing family planning services in Assiut Governorate were invited to complete self-administered questionnaires. The study participants were recruited at the family planning sector monthly meetings of the 13 health directorates of Assiut Governorate, Upper Egypt...
December 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/29193372/summary-of-the-uaa-aaus-guidelines-for-urinary-tract-infections
#15
Hyun-Sop Choe, Seung-Ju Lee, Stephen S Yang, Ryoichi Hamasuna, Shingo Yamamoto, Yong-Hyun Cho, Tetsuro Matsumoto
Urinary tract infections, genital tract infections and sexually transmitted infections are the most prevalent infectious diseases, and the establishment of locally optimized guidelines is critical to provide appropriate treatment. The Urological Association of Asia has planned to develop the Asian guidelines for all urological fields, and the present urinary tract infections, genital tract infections and sexually transmitted infections guideline was the second project of the Urological Association of Asia guideline development, which was carried out by the Asian Association of Urinary Tract Infection and Sexually Transmitted Infection...
November 28, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29193238/experiences-of-living-with-a-sexually-transmitted-disease-an-integrative-review
#16
REVIEW
Toni Haapa, Tarja Suominen, Eija Paavilainen, Jari Kylmä
PURPOSE: This integrative review describes experiences related to living with a sexually transmitted disease (STD). DESIGN: The data search was conducted using the CINAHL, MEDLINE (Ovid), PsycINFO and PubMed databases between the years 2000 and 2016. A manual search was also used. The retrieved data consisted of 33 original articles which were analysed using deductive and inductive content analysis. RESULTS: Based on the results, an infected person has a need for information about STDs and experiences emotions such as a loss of purity and control over his/her body...
November 29, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/29190689/trichomonicidal-and-parasite-membrane-damaging-activity-of-bidesmosic-saponins-from-manilkara-rufula
#17
Patrícia de Brum Vieira, Nícolas Luiz Feijó Silva, Camila Braz Menezes, Márcia Vanusa da Silva, Denise Brentan Silva, Norberto Peporine Lopes, Alexandre José Macedo, Jaume Bastida, Tiana Tasca
The infection caused by Trichomonas vaginalis is the most common but overlooked non-viral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5-nitroimidazoles, but resistance is widespread. New drugs are urgently needed. We reported the effect of crude and purified saponin fractions of Manilkara rufula against Trichomonas vaginalis. The compound responsible for antitrichomonal activity was isolated and identified as an uncommon bidesmosic saponin, Mi-saponin C. This saponin eliminated parasite viability without toxicity against the human vaginal epithelial line (HMVII)...
2017: PloS One
https://www.readbyqxmd.com/read/29186396/genome-sequencing-of-chlamydia-trachomatis-serovars-e-and-f-reveals-substantial-genetic-variation
#18
Thomas Eder, Stefanie Kobus, Sonja Stallmann, Stefanie Stepanow, Karl Köhrer, Johannes H Hegemann, Thomas Rattei
Chlamydia trachomatis (Ctr) is a bacterial pathogen that causes ocular, urogenital and lymph system infections in humans. It is highly abundant and among its serovars, E, F and D are most prevalent in sexually transmitted disease. However, the number of publicly available genome sequences of the serovars E and F, and thereby our knowledge about the molecular architecture of these serovars, is low. Here we sequenced the genomes of six E and F clinical isolates and one E lab strain, in order to study the genetic variance in these serovars...
November 24, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/29186268/quality-of-life-in-men-diagnosed-with-anogenital-warts
#19
Caio Cavassan de Camargo, Maria Paula Barbieri D'Elia, Helio Amante Miot
Anogenital warts are a worldwide public health problem. They consist of epithelial proliferations caused by HPV, whose transmission occurs mainly through sexual intercourse. In this study, we evaluated their impact on the quality of life of adult males. We interviewed 88 men in an outpatient clinic for sexually transmitted diseases at a Brazilian public institution, using the DLQI-BRA questionnaire. Most patients (81%) presented mild or no impairment of quality of life. The main dimensions affected were sex life, symptoms, and embarrassment...
May 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29186267/incidence-of-skin-diseases-diagnosed-in-a-public-institution-comparison-between-2003-and-2014
#20
Livia Maria Zanardi Miguel, Marilia Formentini Scotton Jorge, Bruna Rocha, Hélio Amante Miot
Epidemiology of diseases is influenced by population socio-demographic circumstances. Therefore it can be modified along the time. There are no studies exploring epidemiological transition in dermatology. This study investigated the incidence of dermatoses in new patients from a Brazilian country town public service in 2003 and 2014. There was a significant increase in the incidence of sexually transmitted diseases, leprosy, melasma, pruritus and hidradenitis suppurativa. However, a prominent reduction in scheduling of appointments for surgeries of benign lesions, drug reactions, urticaria and superficial mycoses was detected...
May 2017: Anais Brasileiros de Dermatologia
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