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https://www.readbyqxmd.com/read/28315538/self-administered-premedication-improving-taxane-chemotherapy-treatment%C3%A2
#1
Kristin Roper, Mary Lou Siefert, Frances Fuller, Diane Lucier, Donna L Berry
BACKGROUND: Patients receiving taxane therapy are at risk for hypersensitivity reactions without appropriate premedication management. Patients must understand the importance of taking premedications as prescribed to prevent reactions.
. OBJECTIVES: The objectives of this study were to implement and evaluate a multidisciplinary practice protocol comprised of standardized nursing documentation of premedication regimens, teaching, and patient adherence to at-home premedication in an electronic health record (EHR)...
April 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28306135/how-common-are-pulmonary-and-hepatic-adverse-effects-in-older-adults-prescribed-nitrofurantoin
#2
Karin Claussen, Edward Stocks, Deepa Bhat, Jason Fish, Craig D Rubin
OBJECTIVES: To determine the frequency of serious pulmonary and hepatic adverse events (AEs) in persons aged 65 and older prescribed nitrofurantoin. DESIGN: Retrospective electronic health record (EHR) audit of nitrofurantoin prescriptions and associated AEs. SETTING: Urban academic medical center. PARTICIPANTS: All inpatients and outpatients aged 65 and older prescribed nitrofurantoin from January 1, 2010, to December 31, 2014...
March 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28303255/active-use-of-electronic-health-records-ehrs-and-personal-health-records-phrs-for-epidemiologic-research-sample-representativeness-and-nonresponse-bias-in-a-study-of-women-during-pregnancy
#3
Julie K Bower, Claire E Bollinger, Randi E Foraker, Darryl B Hood, Abigail B Shoben, Albert M Lai
INTRODUCTION: With the growing use of electronic medical records, electronic health records (EHRs), and personal health records (PHRs) for health care delivery, new opportunities have arisen for population health researchers. Our objective was to characterize PHR users and examine sample representativeness and nonresponse bias in a study of pregnant women recruited via the PHR. DESIGN: Demographic characteristics were examined for PHR users and nonusers. Enrolled study participants (responders, n=187) were then compared with nonresponders and a representative sample of the target population...
2017: EGEMS
https://www.readbyqxmd.com/read/28293684/meaningful-use-of-an-electronic-personal-health-record-ephr-among-pediatric-cancer-survivors
#4
Rebecca S Williamson, Brooke O Cherven, Jordan Gilleland Marchak, Paula Edwards, Michael Palgon, Cam Escoffery, Lillian R Meacham, Ann C Mertens
Background and Objectivs: Survivors of pediatric and adolescent cancer are at an increased risk of chronic and debilitating health conditions and require life-long specialized care. Stand-alone electronic personal health records (ePHRs) may aid their self-management. This analysis characterizes young adult survivors and parents who meaningfully use an ePHR, Cancer SurvivorLink(TM), designed for survivors of pediatric and adolescent cancer. METHODS: This was a retrospective observational study of patients seen at a pediatric survivor clinic for annual survivor care...
March 15, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28291496/public-health-surveillance-via-template-management-in-electronic-health-records-tri-service-workflow-s-rapid-response-to-an-infectious-disease-crisis
#5
Holly Berkley, Matthew Barnes, David Carnahan, Janet Hayhurst, Archie Bockhorst, James Neville
OBJECTIVE: To describe the use of template-based screening for risk of infectious disease exposure of patients presenting to primary care medical facilities during the 2014 West African Ebola virus outbreak. METHODS: The Military Health System implemented an Ebola risk-screening tool in primary care settings in order to create early notifications and early responses to potentially infected persons. Three time-sensitive, evidence-based screening questions were developed and posted to Tri-Service Workflow (TSWF) AHLTA templates in conjunction with appropriate training...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291483/risk-factors-for-incident-postdeployment-mental-health-conditions-among-u-s-air-force-medical-service-personnel
#6
Genny M Maupin, Anthony P Tvaryanas, Edward D White, Heather J Lysfjord
The prevalence of postdeployment mental health (PDMH) conditions in military health care personnel appears to be on par with that of other military personnel. However, there is no comprehensive analysis of incident PDMH conditions within the overall population of U.S. Air Force Medical Service personnel. This study explored the epidemiology of incident PDMH conditions among Air Force Medical Service personnel returning from deployment. A cohort survival analysis was conducted of 24,409 subjects without preexisting mental health conditions and at least one deployment during 2003-2013...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28287993/prediction-of-adverse-events-in-patients-undergoing-major-cardiovascular-procedures
#7
Bobak Mortazavi, Nihar Desai, Jing Zhang, Andreas Coppi, Frederick Warner, Harlan Krumholz, Sahand Negahban
Electronic health records (EHR) provide opportunities to leverage vast arrays of data to help prevent adverse events, improve patient outcomes, and reduce hospital costs. This work develops a postoperative complications prediction system by extracting data from the EHR and creating features. The analytic engine then provides model accuracy, calibration, feature ranking, and personalized feature responses. This allows clinicians to interpret the likelihood of an adverse event occurring, general causes for these events, and the contributing factors for each specific patient...
March 1, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28276633/public-health-and-precision-medicine-share-a-goal
#8
Asokan G Vaithinathan, Vanitha Asokan
The advances made in genomics and molecular tools aid public health programs in the investigation of outbreaks and control of diseases by taking advantage of the precision medicine. Precision medicine means "segregating the individuals into subpopulations who vary in their disease susceptibility and response to a precise treatment" and not merely designing of drugs or creation of medical devices. By 2017, the United Kingdom 100,000 Genomes Project is expected to sequence 100,000 genomes from 70,000 patients...
December 16, 2016: Journal of Evidence-based Medicine
https://www.readbyqxmd.com/read/28271977/end-of-life-conversations-and-hospice-placement-association-with-less-aggressive-care-desired-in-the-nursing-home
#9
Joann P Reinhardt, Deirdre Downes, Verena Cimarolli, Patricia Bomba
Education about end-of-life care and treatment options, communication between family and health care providers, and having advance directives and medical orders in place are important for older adults with chronic, progressive decline and end-stage disease who spend their last days in the nursing home. This study used retrospective data (6 months before death) of long-stay nursing home decedents (N = 300) taken from electronic health records to capture the end-of-life experience. Findings showed for almost all decedents, Do Not Resuscitate and Do Not Intubate orders were in place, and just over one-half had Do Not Hospitalize and No Artificial Feeding orders in place...
January 2017: Journal of Social Work in End-of-life & Palliative Care
https://www.readbyqxmd.com/read/28268840/secure-access-to-patient-s-health-records-using-speechxrays-a-mutli-channel-biometrics-platform-for-user-authentication
#10
Emmanouil G Spanakis, Marios Spanakis, Apostolos Karantanas, Kostas Marias
The most commonly used method for user authentication in ICT services or systems is the application of identification tools such as passwords or personal identification numbers (PINs). The rapid development in ICT technology regarding smart devices (laptops, tablets and smartphones) has allowed also the advance of hardware components that capture several biometric traits such as fingerprints and voice. These components are aiming among others to overcome weaknesses and flaws of password usage under the prism of improved user authentication with higher level of security, privacy and usability...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268820/towards-sophisticated-learning-from-ehrs-increasing-prediction-specificity-and-accuracy-using-clinically-meaningful-risk-criteria
#11
Ieva Vasiljeva, Ognjen Arandjelovic
Computer based analysis of Electronic Health Records (EHRs) has the potential to provide major novel insights of benefit both to specific individuals in the context of personalized medicine, as well as on the level of population-wide health care and policy. The present paper introduces a novel algorithm that uses machine learning for the discovery of longitudinal patterns in the diagnoses of diseases. Two key technical novelties are introduced: one in the form of a novel learning paradigm which enables greater learning specificity, and another in the form of a risk driven identification of confounding diagnoses...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267788/dementia-incidence-trend-over-1992-2014-in-the-netherlands-analysis-of-primary-care-data
#12
Emma F van Bussel, Edo Richard, Derk L Arts, Astrid C J Nooyens, Preciosa M Coloma, Margot W M de Waal, Marjan van den Akker, Marion C J Biermans, Markus M J Nielen, Kees van Boven, Hugo Smeets, Fiona E Matthews, Carol Brayne, Wim B Busschers, Willem A van Gool, Eric P Moll van Charante
BACKGROUND: Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health in early age have been suggested to be bringing about this effect. The aim of this study was to estimate the age-specific dementia incidence trend in primary care records from a large population in the Netherlands. METHODS AND FINDINGS: A dynamic cohort representative of the Dutch population was composed using primary care records from general practice registration networks (GPRNs) across the country...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28262574/health-adjusted-life-expectancy-in-hiv-positive-and-hiv-negative-men-and-women-in-british-columbia-canada-a-population-based-observational-cohort-study
#13
Robert S Hogg, Oghenowede Eyawo, Alexandra B Collins, Wendy Zhang, Shahab Jabbari, Mark W Hull, Viviane Dias Lima, Tareq Ahmed, Claire E Kendall, Keri N Althoff, Amy C Justice, Rolando Barrios, Jeannie Shoveller, Julio S G Montaner
BACKGROUND: We sought to understand whether people living with HIV (PLHIV) ever on highly active antiretroviral therapy (ART) follow a pattern where morbidity is compressed into the last years of life or lessened as people age. We aimed to estimate health-adjusted life expectancy (HALE) among adults living with and without HIV, and examine dependency between causes of comorbidities. METHODS: The Comparative Outcomes and Service Utilization Trends (COAST) study is a retrospective cohort of adults (≥20 years) including all known PLHIV and a 10% random sample of the general population of British Columbia, and with longitudinal data spanning from April 1, 1996, to Dec 31, 2012...
March 2, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28259737/medication-adherence-molecular-monitoring-and-clinical-outcomes-in-patients-with-chronic-myelogenous-leukemia-in-a-large-hmo
#14
Reina Haque, Jiaxiao Shi, Joanie Chung, Xiaoqing Xu, Chantal Avila, Christopher Campbell, Syed A Ahmed, Lei Chen, Joanne E Schottinger
OBJECTIVE: Our objective was to examine the association between adherence to tyrosine kinase inhibitors (TKIs) and molecular monitoring and the risk of disease progression or mortality among patients with chronic phase chronic myeloid leukemia (CML). DESIGN: We assembled a retrospective cohort of patients with CML (chronic phase, no prior cancer history, and confirmed to be Philadelphia chromosome positive) using data from electronic health records and chart reviews...
March 1, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28257920/a-web-based-personalized-risk-communication-and-decision-making-tool-for-women-with-dense-breasts-design-and-methods-of-a-randomized-controlled-trial-within-an-integrated-health-care-system
#15
Sarah Knerr, Karen J Wernli, Kathleen Leppig, Kelly Ehrlich, Amanda L Graham, David Farrell, Chalanda Evans, George Luta, Marc D Schwartz, Suzanne C O'Neill
BACKGROUND: Mammographic breast density is one of the strongest risk factors for breast cancer after age and family history. Mandatory breast density disclosure policies are increasing nationally without clear guidance on how to communicate density status to women. Coupling density disclosure with personalized risk counseling and decision support through a web-based tool may be an effective way to allow women to make informed, values-consistent risk-management decisions without increasing distress...
February 28, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28257309/patient-centered-anesthesia-triage-system-predicts-asa-physical-status
#16
F Kayser Enneking, Nila S Radhakrishnan, Kent Berg, Saharsh Patel, Judith M Wishin, Terrie Vasilopoulos
BACKGROUND: The purpose of this study was to validate a patient-centered anesthesia triage system (PCATS) by examining its association with, and predictive value of, ASA physical status (PS) classification. ASA PS classification is a widely used indicator of health status and the predictor of risk of perioperative complications. Thus, ASA PS is a good triage point such that healthy surgical patients (ASA PS I and II) undergoing low-complexity surgery are assessed by telephone, whereas less-healthy patients (ASA PS III and IV) or those patients undergoing highly complex surgery are seen in person at a presurgical clinic...
March 2, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28254735/a-personal-electronic-health-record-study-protocol-of-a-feasibility-study-on-implementation-in-a-real-world-health-care-setting
#17
Dominik Ose, Aline Kunz, Sabrina Pohlmann, Helene Hofmann, Markus Qreini, Johannes Krisam, Lorenz Uhlmann, Christian Jacke, Eva C Winkler, Hans-Joachim Salize, Joachim Szecsenyi
BACKGROUND: A significant potential for patient empowerment is seen in concepts aiming to give patients access to their personal health information (PHI) and to share this PHI across different care settings and health systems. Personal health records (PHRs) and the availability of information through health information exchanges are considered to be key components of effective and efficient health care. With tethered PHRs, as often used in the United States, patients' opportunities to manage their PHI are strongly restricted...
March 2, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28253851/a-systematic-review-of-studies-with-a-representative-sample-of-refugees-and-asylum-seekers-living-in-the-community-for-participation-in-mental-health-research
#18
Joanne C Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas, Graham Meadows
BACKGROUND: The aim was to review the literature to identify the most effective methods for creating a representative sample of refugee and asylum seeker groups living in the community to participate in health and mental health survey research. METHODS: A systematic search of academic and grey literature was conducted for relevant literature with 'hidden' groups published between January 1995 and January 2016. The main search used Medline, PsycINFO, EMBASE, CINAHL and SCOPUS electronic databases...
March 2, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28253838/predictors-and-incidence-of-sexually-transmitted-hepatitis-c-virus-infection-in-hiv-positive-men-who-have-sex-with-men
#19
Nicholas A Medland, Eric P F Chow, Catriona S Bradshaw, Timothy H R Read, Joseph J Sasadeusz, Christopher K Fairley
BACKGROUND: Sexual transmission of Hepatitis C virus (HCV) in men who have sex with men (MSM) and its interaction with HIV status, sexually transmitted infections and sexual behaviour is poorly understood. We assessed the incidence and predictors of HCV infection in HIV positive MSM. METHODS: The electronic medical record and laboratory results from HIV positive MSM in care at a large urban public specialist HIV clinic embedded in a sexual health centre in Melbourne Australia were collected...
March 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28237052/retention-in-buprenorphine-treatment-is-associated-with-improved-hcv-care-outcomes
#20
B L Norton, A Beitin, M Glenn, J DeLuca, A H Litwin, C O Cunningham
Persons who inject drugs, most of whom are opioid dependent, comprise the majority of the HCV infected in the United States. As the national opioid epidemic unfolds, increasing numbers of people are entering the medical system to access treatment for opioid use disorder, specifically with buprenorphine. Yet little is known about HCV care in patients accessing buprenorphine-based opioid treatment. We sought to determine the HCV prevalence, cascade of care, and the association between patient characteristics and completion of HCV cascade of care milestones for patients initiating buprenorphine treatment...
April 2017: Journal of Substance Abuse Treatment
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