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Camille Loranger, Linda Moreau, Denis Sasseville
BACKGROUND: Aircraft building exposes workers to irritant and sensitizing products. OBJECTIVE: The aim of this article was to study occupational dermatoses among aircraft workers over 25 years. METHODS: The files of aerospace workers referred between 1990 and 2015 were extracted from the database of the McGill University Health Centre contact dermatitis clinic. These were subdivided according to demographics, type of work, patch testing results, and final diagnosis...
May 2018: Dermatitis
Yasuhiko Kawai, Hiroshi Muarakami, Jocelyne S Feine
OBJECTIVES: The use of a simplified method (S) of fabricating complete dentures has been shown to be more cost-efficient than the traditional method (T), and there are no negative consequences that detract from the cost savings in the short term. However, it is not clear whether this remains constant over a decade. The objective of this study was to clarify patients' perspectives and determine any differences between the dentures fabricated with these two different techniques after a decade of use...
May 11, 2018: Journal of Dentistry
Martin Bailey, Tomas Corcoran, Stephan Schug, Andrew Toner
Chronic post-surgical pain (CPSP) occurs in 12% of surgical populations and is a high priority for perioperative research. Systemic lidocaine may modulate several of the pathophysiological processes linked to CPSP. This systematic review aims to identify and synthesize the evidence linking lidocaine infusions and CPSP.The authors conducted a systematic literature search of the major medical databases from inception until October 2017. Trials that randomized adults without baseline pain to perioperative lidocaine infusion or placebo were included if they reported on CPSP...
May 11, 2018: Pain
Keiko Kurita, Eugenia L Siegler, M Cary Reid, Renee C Maciejewski, Holly G Prigerson
CONTEXT: Patients with advanced cancer often overestimate their time left to live. Those who have heightened awareness of their cognitive and physical deficits at the end of life may have a better prognostic understanding. OBJECTIVES: We sought to investigate the extent to which patients' self-reports of physical well-being and cognitive function were associated with prognostic understanding. METHODS: Logistic regression analyzed data from Coping with Cancer II, a National Cancer Institute-funded study of patients with advanced cancer from nine US cancer clinics...
May 9, 2018: Journal of Pain and Symptom Management
Kamlesh Khunti, James R Gavin, Andrew J M Boulton, Rick Blickstead, Margaret McGill, Antonio Ceriello, Itamar Raz, Shaukat Sadikot, David A Wood, Xavier Cos, Sanjay Kalra, Ashok Kumar Das, Cutberto Espinosa López
Diabetes is epidemic worldwide and places a huge burden on healthcare systems. The majority of the cost of type 2 diabetes (T2D) is related to hospitalization and the management of complications, and these also have a negative impact on the individual's quality of life. The Berlin Declaration is a global call for early action for the identification of high risk individuals, prevention of T2D and the prevention of complications in those with T2D, through prevention, early detection, early control and early access to the right multidisciplinary interventions...
May 8, 2018: Primary Care Diabetes
Peter McGill, Leah Vanono, Will Clover, Emmett Smyth, Vivien Cooper, Lisa Hopkins, Nick Barratt, Christopher Joyce, Kate Henderson, Sheila Sekasi, Susy Davis, Roy Deveau
BACKGROUND: Improving the quality of social care through the implementation of setting-wide positive behaviour support (SWPBS) may reduce and prevent challenging behaviour. METHOD: Twenty-four supported accommodation settings were randomized to experimental or control conditions. Settings in both groups had access to individualized PBS either via the organisation's Behaviour Support Team or from external professionals. Additionally, within the experimental group, social care practice was reviewed and improvement programmes set going...
May 8, 2018: Research in Developmental Disabilities
Wu Xu, Yan Zhi, Yongsheng Yuan, Bingfeng Zhang, Yuting Shen, Hui Zhang, Kezhong Zhang, Yun Xu
Despite a growing body of evidence suggests that abnormal iron metabolism plays an important role in the pathogenesis of Parkinson's disease (PD), few studies explored its role in non-motor symptoms (NMS) of PD. The present study aimed to investigate the relationship between abnormal iron metabolism and NMS of PD. Seventy PD patients and 64 healthy controls were consecutively recruited to compare serum iron, ceruloplasmin, ferritin, and transferrin levels. We evaluated five classic NMS, including depression, anxiety, pain, sleep disorder, and autonomic dysfunction in PD patients using the Hamilton Depression Scale (HAMD), the Hamilton Anxiety Scale (HAMA), the short form of the McGill Pain Questionnaire, the Pittsburgh Sleep Quality Index and the Scale for Outcomes in Parkinson's disease for Autonomic Symptoms, respectively...
May 10, 2018: Journal of Neural Transmission
Faezeh Monji, Farshad Hashemian, Mohammad-Hossein Salehi Surmaghi, Fatemeh Mohammadyari, Saeid Ghiyaei, Alireza Soltanmohammadi
OBJECTIVES: In Iranian folklore medicine, boiled extract of Stachys lavandulifolia Vahl is reputed to have therapeutic effects in painful disorders. This study evaluated the efficacy of the standardized formulation of S. lavandulifolia Vahl in reducing pain in primary dysmenorrhea, which is known to be a common disorder with significant impact on quality of life. DESIGN: A randomized, double blind, crossover, placebo-controlled pilot study. SETTINGS/LOCATION: Bu-Ali Hospital affiliated with Tehran Medical Branch, Islamic Azad University...
May 9, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
Christian Balkovec, Jim Veldhuis, John W Baird, G Wayne Brodland, Stuart M McGill
BACKGROUND: Disc height loss and osteophytes change the local mechanical environment in the spine; while previous research has examined kinematic dysfunction under degenerative change, none has looked at the influence of disc height loss and osteophytes throughout movement. METHODS: Twenty patients with pain related to the head, neck or shoulders were imaged via videofluoroscopy as they underwent sagittal-plane flexion and extension. A clinician graded disc height loss and osteophytes as "severe/moderate", "mild", or "none"...
April 26, 2018: Clinical Biomechanics
Anne MacDonald, Peter McGill, Glynis Murphy
BACKGROUND: Positive Behavioural Support (PBS) has been shown to be effective in minimizing challenging behaviour and improving the lives of people with intellectual disabilities. Training in PBS is an important factor in achieving good coverage in the use of PBS. The aim of this study was to evaluate the impact of training managers of social care services in PBS. METHOD: A year-long training programme in PBS was delivered to 50 managers of community-based services for people with challenging behaviour...
May 8, 2018: Journal of Applied Research in Intellectual Disabilities: JARID
Rossella Viscito, Paola Emilia Ferrara, Concetta Ljoka, Romina Pascuzzo, Loredana Maggi, Gianpaolo Ronconi, Calogero Foti
Mesotherapy is a technique that treats locoregional pain with intradermal injection of a drug in the affected area. Its short-term efficacy was observed in patients with low back pain using both normal saline solution, if there were contraindications to drugs' use, or a cocktail of drugs (normal saline solution, lidocaine hydrochloride, and lysine acetylsalicylate), whereas only the latter provided benefit for up to three months after treatment. The aim of this study was to measure the effects of mesotherapy in patients affected by neck pain in spondylarthrosis, a common pathology in rehabilitation, associated with significant disability and increased health expenditure...
January 2018: Igiene e Sanità Pubblica
James R Wright, Samuel J M M Alberti, Christopher Lyons, Richard S Fraser
CONTEXT: - In the early 1900s, it was common practice to retain, prepare, and display instructive pathologic specimens to teach pathology to medical trainees and practitioners; these collections were called medical museums. Maude Abbott established her reputation by developing expertise in all aspects of medical museum work. She was a founder of the International Association of Medical Museums (later renamed the International Academy of Pathology) and became an internationally renowned expert on congenital heart disease...
May 7, 2018: Archives of Pathology & Laboratory Medicine
Nathalie Bleau, Alexandre Gauvreau, Amira El-Messidi, Haim Arie Abenhaim
OBJECTIVE: Ultrasound is the primary modality used to evaluate adnexal lesions. Follow-up recommendations for ovarian cysts remain controversial between gynaecologists and radiologists. The objective of this study was to compare practice patterns for adnexal masses described on ultrasound on the basis of the interpreter's field of specialty. METHODS: This study was conducted within the McGill University Hospital Network at two hospitals that differ in the department of interpretation of pelvic ultrasounds...
May 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Dayna E McGill, Lisa K Volkening, Deborah A Butler, Kara R Harrington, Michelle L Katz, Lori M Laffel
BACKGROUND: Consistent use of continuous glucose monitoring (CGM) has been associated with improved glycemic control in youth with type 1 diabetes (T1D). There are many barriers to device uptake and continued use. There is a need to understand patient-specific characteristics when considering CGM. We evaluated patterns of CGM use and associations between baseline psychosocial measures and frequency of CGM use over 1 year. METHODS: Youth with T1D (n = 120), ages 8-18 years, completed questionnaires at CGM initiation and after 6 and 12 months assessing depressive symptoms, diabetes burden, and diabetes-specific and generic quality of life (QOL)...
May 4, 2018: Diabetes Technology & Therapeutics
Trevor J McGill, David J Wilson, Jonathan Stoddard, Lauren M Renner, Martha Neuringer
Transplantation of potentially therapeutic cells into the subretinal space is a promising prospective therapy for the treatment of retinal degenerative diseases including age-related macular degeneration (AMD). In rodent models with photoreceptor degeneration, subretinal transplantation of cell suspensions has repeatedly been demonstrated to rescue behaviorally measured vision, maintain electrophysiological responses from the retina and the brain, and slow the degeneration of rod and cone photoreceptors for extended periods...
2018: Advances in Experimental Medicine and Biology
Courtney Scerbak, Elena Vayndorf, Alicia Hernandez, Colin McGill, Barbara Taylor
Medicinal berries are appreciated for their health benefits, in traditional ecological knowledge and nutrition science. Determining the cellular mechanisms underlying the effects of berry supplementation may contribute to our understanding of aging. Here, we report that lowbush cranberry (Vaccinium vitis-idaea) treatment causes marked nuclear localization of the central aging-related transcription factor DAF-16/FOXO in aged Caenorhabditis elegans. Further, functional DAF-16 is required for the lifespan extension, improved mechanosensation, and posterior touch receptor neuron morphological changes induced by lowbush cranberry treatments...
May 1, 2018: GeroScience
Norman Ratcliffe, Stacey Adlard, Gabrielle Stowasser, Rona McGill
Optimal foraging theory predicts that when food is plentiful all individuals should take a small range of preferred prey types, but as competition increases less preferred prey will be included in the diet. This dietary switching may not be uniform among individuals, which produces discrete dietary clusters. We tested this hypothesis for gentoo penguins at Bird Island, South Georgia, using stable isotope analysis and biologging. Competition, in the form of the density of foraging dives, increased markedly from incubation to chick-rearing owing to increased foraging effort...
May 1, 2018: Scientific Reports
Corinne A Riddell, Sam Harper, Magdalena Cerdá, Jay S Kaufman
Background: The extent to which differences in homicide and suicide rates in black versus white men vary by U.S. state is unknown. Objective: To compare the rates of firearm and nonfirearm homicide and suicide in black and white non-Hispanic men by U.S. state and to examine whether these deaths are associated with state prevalence of gun ownership. Design: Surveillance study. Setting: 50 states and the District of Columbia, 2008 to 2016...
April 24, 2018: Annals of Internal Medicine
Arsalan Ghorbanpour, Mahmoud Reza Azghani, Mohammad Taghipour, Zahra Salahzadeh, Fariba Ghaderi, Ali E Oskouei
[Purpose] The aim of this study was to compare the effects of "McGill stabilization exercises" and "conventional physiotherapy" on pain, functional disability and active back flexion and extension range of motion in patients with chronic non-specific low back pain. [Subjects and Methods] Thirty four patients with chronic non-specific low back pain were randomly assigned to McGill stabilization exercises group (n=17) and conventional physiotherapy group (n=17). In both groups, patients performed the corresponding exercises for six weeks...
April 2018: Journal of Physical Therapy Science
Ravena C de Carvalho, Julia R Parisi, Wiliam A Prado, João E de Araújo, Andreia M Silva, Josie R T Silva, Marcelo L Silva
The objective of this study was to compare the effects of one or multiple sessions of electroacupuncture (EA) in patients with chronic low back pain. The outcome measures were visual analog score (VAS), pressure pain threshold (PPT), McGill pain questionnaire (MPQ), Roland Morris disability questionnaire (RMDQ), low back skin temperature, surface electromyography of longissimus muscle (contraction/rest) and blood cytokines. After examination (AV0), patients were submitted to EA (2 Hz, 30 minutes, bilaterally at the SP6, BL23, BL31, BL32, BL33, and BL60) and were revaluated after one week (AV1)...
April 2018: Journal of Acupuncture and Meridian Studies
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