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https://www.readbyqxmd.com/read/28325536/self-reported-neuropathic-pain-characteristics-of-women-with-provoked-vulvar-pain-a-preliminary-investigation
#1
Emma Dargie, Ian Gilron, Caroline F Pukall
BACKGROUND: Provoked vestibulodynia (PVD) is a common chronic genital pain condition affecting approximately 12% of premenopausal women. Although parallels have been drawn between PVD and neuropathic pain (NP), no studies have examined self-reported NP characteristics in PVD. AIM: To explore pain symptoms that resemble NP reported by those with PVD and compare responses with those with an established NP condition. METHODS: Women with provoked vulvar pain (PVP; n = 65) completed online questionnaires designed to assess characteristics of NP...
March 15, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28324053/hepatic-insulin-resistance-and-altered-gluconeogenic-pathway-in-premature-baboons
#2
Lisa McGill-Vargas, Amalia Gastaldelli, Hanyu Liang, Diana Anzueto Guerra, Teresa Johnson-Pais, Steven Seidner, Donald McCurnin, Giovanna Muscogiuri, Ralph DeFronzo, Nicolas Musi, Cynthia Blanco
Premature infants have altered glucose regulation early in life and increased risk for diabetes in adulthood. Although prematurity leads to an increased risk of diabetes and metabolic syndrome in adult life, the role of hepatic glucose regulation and adaptation to an early extra-uterine environment in preterm infants remain unknown. The purpose of this study was to investigate developmental differences in glucose metabolism, hepatic protein content and gene expression of key insulin signaling/gluconeogenic molecules...
January 17, 2017: Endocrinology
https://www.readbyqxmd.com/read/28319701/tracking-effluent-discharges-in-undisturbed-stony-soil-and-alluvial-gravel-aquifer-using-synthetic-dna-tracers
#3
Liping Pang, Beth Robson, Kata Farkas, Erin McGill, Arvind Varsani, Lea Gillot, Jinhua Li, Phillip Abraham
With the intensification of human activities, fresh water resources are increasingly being exposed to contamination from effluent disposal to land. Thus, there is a greater need to identify the sources and pathways of water contamination to enable the development of better mitigation strategies. To track discharges of domestic effluent into soil and groundwater, 10 synthetic double-stranded DNA (dsDNA)(3) tracers were developed in this study. Laboratory column experiment and field groundwater and soil lysimeter studies were carried out spiking DNA with oxidation-pond domestic effluent...
March 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28314551/prevalence-and-correlates-of-pain-in-fatigued-patients-with-type-1-diabetes
#4
Juliane Menting, Cees J Tack, Hans Knoop
OBJECTIVE: To investigate the prevalence, location and severity of pain, as well as its association with psychosocial and clinical variables and its impact on functional impairment in fatigued patients with type 1 diabetes. METHODS: 120 severely fatigued patients with type 1 diabetes completed questionnaires on pain (McGill Pain Questionnaire, MPQ; Short Form Health Survey subscale bodily pain, SF-36), fatigue severity (Checklist Individual Strength subscale fatigue severity, CIS), depressive symptoms (Beck Depression Inventory Primary Care, BDI-PC) and functional impairment (Sickness Impact Profile-8, SIP-8)...
April 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28302700/predicting-suicidal-behaviours-using-clinical-instruments-systematic-review-and-meta-analysis-of-positive-predictive-values-for-risk-scales
#5
REVIEW
Gregory Carter, Allison Milner, Katie McGill, Jane Pirkis, Navneet Kapur, Matthew J Spittal
BackgroundPrediction of suicidal behaviour is an aspirational goal for clinicians and policy makers; with patients classified as 'high risk' to be preferentially allocated treatment. Clinical usefulness requires an adequate positive predictive value (PPV).AimsTo identify studies of predictive instruments and to calculate PPV estimates for suicidal behaviours.MethodA systematic review identified studies of predictive instruments. A series of meta-analyses produced pooled estimates of PPV for suicidal behaviours...
March 16, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28301498/knowledge-attitudes-and-practices-kap-relating-to-brucellosis-in-smallholder-dairy-farmers-in-two-provinces-in-pakistan
#6
Shumaila Arif, Peter C Thomson, Marta Hernandez-Jover, David M McGill, Hassan Mahmood Warriach, Jane Heller
The present study aimed to assess the extent of knowledge and understanding of brucellosis in smallholder dairy farmers and identify practices at the farm and household level that might pose a risk for humans contracting brucellosis. Between February and June 2015 a cross-sectional study was conducted among smallholder farms (n = 420) in five districts of Punjab and two districts of Sindh province. Farmers were interviewed using a questionnaire to obtain information on farmers' knowledge about brucellosis and the potential risks for contracting the disease that are present for dairy farmers and their families...
2017: PloS One
https://www.readbyqxmd.com/read/28299294/the-effect-of-chamomile-cream-on-episiotomy-pain-in-primiparous-women-a-randomized-clinical-trial
#7
Maryam Aradmehr, Sedigheh Azhari, Sedigheh Ahmadi, Elham Azmoude
Introduction: Episiotomy is a surgical incision made in the perineum to enlarge it. Perineal pain is the most common complaint of mothers after episiotomy. Chamomile extract has been proposed as a sedative in traditional medicine. This study was conducted to assess the effect of chamomile cream on the pain after episiotomy. Methods: This triple blind clinical trial was performed on 114 eligible women at Ommolbanin Hospital in Mashhad, Iran in 2014.They were randomly assigned to two groups using random blocks...
March 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28294643/a-videofluoroscopy-based-tracking-algorithm-for-quantifying-the-time-course-of-human-intervertebral-displacements
#8
Christian Balkovec, Jim H Veldhuis, John W Baird, G Wayne Brodland, Stuart M McGill
The motions of individual intervertebral joints can affect spine motion, injury risk, deterioration, pain, treatment strategies, and clinical outcomes. Since standard kinematic methods do not provide precise time-course details about individual vertebrae and intervertebral motions, information that could be useful for scientific advancement and clinical assessment, we developed an iterative template matching algorithm to obtain this data from videofluoroscopy images. To assess the bias of our approach, vertebrae in an intact porcine spine were tracked and compared to the motions of high-contrast markers...
March 15, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28294632/do-vulvodynia-tcm-patterns-differ-by-pain-types-beginning-evidence-supporting-the-concept
#9
Judith M Schlaeger, Hui Yan Cai, Xu Nenggui, Alana D Steffens, Wang Lin, Diana J Wilkie
INTRODUCTION: Vulvodynia affects a maximum of 14 million U.S. women; however, it has not been adequately characterized. Traditional Chinese Medicine (TCM) offers pattern diagnoses that may be considered vulvodynia phenotypes and may guide the development of more targeted treatments. OBJECTIVES: In women with vulvodynia, to explore relationships between the TCM patterns and pain. DESIGN/METHODS: In an exploratory study, 36 women diagnosed with vulvodynia had a TCM assessment and completed the Short Form McGill Pain Questionnaire (SF-MPQ)...
March 15, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28294367/the-role-of-the-facilitator-in-couple-relationship-education
#10
Scott A Ketring, Angela B Bradford, Stephanie Y Davis, Francesca Adler-Baeder, Julianne McGill, Thomas A Smith
While much of the Couple Relationship Education (CRE) research has focused on participant factors, unexpectedly little research has considered how characteristics of those providing the programming shape its efficacy. The current study draws upon a diverse sample of 225 couples who received CRE from community educators to examine how facilitation alliance is related to relationship outcomes for men and women and whether having a facilitator with similar demographic characteristics is related to the alliance...
March 11, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28282756/the-effect-of-short-term-isometric-training-on-core-torso-stiffness
#11
Benjamin Lee, Stuart McGill
"Core" exercise is a basic part of many physical training regimens with goals ranging from rehabilitation of spine and knee injuries to improving athletic performance. Core stiffness has been proposed to perform several functions including reducing pain by minimising joint micro-movements, and enhancing strength and speed performance. This study probes the links between a training approach and immediate but temporary changes in stiffness. Passive and active stiffness was measured on 24 participants; 12 having little to no experience in core training (inexperienced), and the other 12 being athletes experienced to core training methods; before and after a 15 min bout of isometric core exercises...
September 26, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28272378/perception-of-policy-and-environmental-action-to-promote-healthy-behaviors-in-african-american-communities
#12
Clifton Addison, Brenda W Campbell Jenkins, Monique White, Frances Henderson, Dorothy J McGill, Donna Antoine-LaVigne, Marinelle Payton
The present study aimed to examine the perceptions of African American communities regarding the involvement of political leaders in facilitating policy and environmental change promoting healthy eating and physical activity. We selected the Metro Jackson Area comprised of Hinds, Madison and Rankin Counties because it is a combination of urban and rural communities. The sample consisted of 70 participants from seven sites. A total of seven focus groups were asked to respond to one question to assess political leaders' involvement in healthy living: "When you think about your political leaders that you have in the Jackson, Mississippi area, do any of them promote healthy eating and physical activity?" Focus groups consisted of six to 12 participants and were asked to comment on their participation in physical activity...
March 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28272220/clinical-study-of-duloxetine-hydrochloride-combined-with-doxazosin-for-the-treatment-of-pain-disorder-in-chronic-prostatitis-chronic-pelvic-pain-syndrome-an-observational-study
#13
Mingxin Zhang, Hanzhong Li, Zhigang Ji, Dexin Dong, Su Yan
To explore the safety and efficacy of the selective 5-serotonin and norepinephrine reuptake inhibitor duloxetine hydrochloride and alpha-adrenergic receptor blocker (alpha-blocker) doxazosin mesylate-controlled tablets in the treatment of pain disorder in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).In all, 150 patients were enrolled and 126 patients completed the study (41 patients in the doxazosin group, 41 patients in the sertraline group, and 44 patients in the duloxetine group). This was an open randomized 6-month study...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28264503/wearable-device-based-gait-recognition-using-angle-embedded-gait-dynamic-images-and-a-convolutional-neural-network
#14
Yongjia Zhao, Suiping Zhou
The widespread installation of inertial sensors in smartphones and other wearable devices provides a valuable opportunity to identify people by analyzing their gait patterns, for either cooperative or non-cooperative circumstances. However, it is still a challenging task to reliably extract discriminative features for gait recognition with noisy and complex data sequences collected from casually worn wearable devices like smartphones. To cope with this problem, we propose a novel image-based gait recognition approach using the Convolutional Neural Network (CNN) without the need to manually extract discriminative features...
February 28, 2017: Sensors
https://www.readbyqxmd.com/read/28259406/evaluation-of-the-national-research-council-2001-dairy-model-and-derivation-of-new-prediction-equations-2-rumen-degradable-and-undegradable-protein
#15
R R White, Y Roman-Garcia, J L Firkins, P Kononoff, M J VandeHaar, H Tran, T McGill, R Garnett, M D Hanigan
This work evaluated the National Research Council (NRC) dairy model (2001) predictions of rumen undegradable (RUP) and degradable (RDP) protein compared with measured postruminal non-ammonia, nonmicrobial (NANMN) and microbial N flows. Models were evaluated using the root mean squared prediction error (RMSPE) as a percent of the observed mean, mean and slope biases as percentages of mean squared prediction error (MSPE), and concordance correlation coefficient (CCC). The NRC (2001) over-estimated NANMN by 18% and under-estimated microbial N by 14%...
March 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28259403/evaluation-of-the-national-research-council-2001-dairy-model-and-derivation-of-new-prediction-equations-1-digestibility-of-fiber-fat-protein-and-nonfiber-carbohydrate
#16
R R White, Y Roman-Garcia, J L Firkins, M J VandeHaar, L E Armentano, W P Weiss, T McGill, R Garnett, M D Hanigan
Evaluation of ration balancing systems such as the National Research Council (NRC) Nutrient Requirements series is important for improving predictions of animal nutrient requirements and advancing feeding strategies. This work used a literature data set (n = 550) to evaluate predictions of total-tract digested neutral detergent fiber (NDF), fatty acid (FA), crude protein (CP), and nonfiber carbohydrate (NFC) estimated by the NRC (2001) dairy model. Mean biases suggested that the NRC (2001) lactating cow model overestimated true FA and CP digestibility by 26 and 7%, respectively, and under-predicted NDF digestibility by 16%...
March 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28254107/protocol-testing-the-relevance-of-acupuncture-theory-in-the-treatment-of%C3%A2-myofascial-pain-in-the-upper-trapezius-muscle
#17
Dale S Elsdon, Selina Spanswick, Chris Zaslawski, Peter C Meier
A protocol for a prospective single-blind parallel four-arm randomized placebo-controlled trial with repeated measures was designed to test the effects of various acupuncture methods compared with sham. Eighty self-selected participants with myofascial pain in the upper trapezius muscle were randomized into four groups. Group 1 received acupuncture to a myofascial trigger point (MTrP) in the upper trapezius. Group 2 received acupuncture to the MTrP in addition to relevant distal points. Group 3 received acupuncture to the relevant distal points only...
January 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28253400/long-term-characterization-of-retinal-degeneration-in-royal-college-of-surgeons-rats-using-spectral-domain-optical-coherence-tomography
#18
Renee C Ryals, Michael D Andrews, Shreya Datta, Aaron S Coyner, Cody M Fischer, Yuquan Wen, Mark E Pennesi, Trevor J McGill
Purpose: Prospective treatments for age-related macular degeneration and inherited retinal degenerations are commonly evaluated in the Royal College of Surgeons (RCS) rat before translation into clinical application. Historically, retinal thickness obtained through postmortem anatomic assessments has been a key outcome measure; however, utility of this measurement is limited because it precludes the ability to perform longitudinal studies. To overcome this limitation, the present study was designed to provide a baseline longitudinal quantification of retinal thickness in the RCS rat by using spectral-domain optical coherence tomography (SD-OCT)...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28253307/effects-of-systemic-lidocaine-versus-magnesium-administration-on-postoperative-functional-recovery-and-chronic-pain-in-patients-undergoing-breast-cancer-surgery-a-prospective-randomized-double-blind-comparative-clinical-trial
#19
Myoung Hwa Kim, Ki Young Lee, Seho Park, Seung Il Kim, Hyung Seok Park, Young Chul Yoo
INTRODUCTION: We aimed to compare the effects of intraoperative lidocaine and magnesium on postoperative functional recovery and chronic pain after mastectomy due to breast cancer. Systemic lidocaine and magnesium reduce pain hypersensitivity to surgical stimuli; however, their effects after mastectomy have not been evaluated clearly. METHODS: In this prospective, double-blind, clinical trial, 126 female patients undergoing mastectomy were randomly assigned to lidocaine (L), magnesium (M), and control (C) groups...
2017: PloS One
https://www.readbyqxmd.com/read/28251729/sham-acupuncture-is-as-efficacious-as-true-acupuncture-for-the-treatment-of-ibs-a-randomized-placebo-controlled-trial
#20
C Lowe, A Aiken, A G Day, W Depew, S J Vanner
BACKGROUND: Irritable bowel syndrome (IBS) patients increasingly seek out acupuncture therapy to alleviate symptoms, but it is unclear whether the benefit is due to a treatment-specific effect or a placebo response. This study examined whether true acupuncture is superior to sham acupuncture in relieving IBS symptoms and whether benefits were linked to purported acupuncture mechanisms. METHODS: A double blind sham controlled acupuncture study was conducted with Rome I IBS patients receiving twice weekly true acupuncture for 4 weeks (n=43) or sham acupuncture (n=36)...
March 2, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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