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https://www.readbyqxmd.com/read/28922081/clinical-outcomes-following-conservative-management-of-chronic-traumatic-cervical-myelopathy-a-case-report
#1
Justin Bridges, Roberto Sandoval
BACKGROUND AND PURPOSE: There is limited evidence supporting the conservative management of patients with cervical myelopathy. The purpose of this report is to describe the intervention and outcomes of conservative physical therapy interventions for one patient with chronic cervical myelopathy. CASE DESCRIPTION: This case was a 50-year-old male who sustained a neck injury following a rear-end collision 4 years prior to this therapeutic episode. The patient presented with decreased range of motion in the cervical spine and right upper extremity, strength deficits, altered sensation, poor posture, and reported chronic cervical region pain and difficulty sleeping...
September 18, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28919509/molecular-and-macro-scale-analysis-of-enzyme-crosslinked-silk-hydrogels-for-rational-biomaterial-design
#2
Meghan McGill, Jeannine M Coburn, Benjamin P Partlow, Xuan Mu, David L Kaplan
Silk fibroin-based hydrogels have exciting applications in tissue engineering and therapeutic molecule delivery; however, their utility is dependent on their diffusive properties. The present study describes a molecular and macro-scale investigation of enzymatically-crosslinked silk fibroin hydrogels, and demonstrates that these systems have tunable crosslink density and diffusivity. We developed a liquid chromatography tandem mass spectroscopy (LC-MS/MS) method to assess the quantity and order of covalent tyrosine crosslinks in the hydrogels...
September 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28917347/optical-diagnosis-of-early-colorectal-cancer-riding-the-highs%C3%A2-and-lows-of-the-japanese-narrow-band-imaging-expert%C3%A2-team-classification
#3
EDITORIAL
Sarah K McGill, Roy Soetikno, Tonya Kaltenbach
No abstract text is available yet for this article.
October 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28915401/the-modified-ketogenic-diet-for-adults-with-refractory-epilepsy-an-evaluation-of-a-set-up-service
#4
Kirsty J Martin-McGill, Michael D Jenkinson, Catrin Tudur Smith, Anthony G Marson
PURPOSE: The ketogenic diet (KD) has been proven to be effective in children with refractory epilepsy and is recommended by the National Institute of Health and Care Excellence (NICE). There is no randomised control trial (RCT) evidence for the clinical or cost effectiveness of KD in adults, for whom the KD is not currently recommended. We assessed the feasibility of the modified ketogenic diet (MKD) in adults with refractory epilepsy along with the willingness of patients to participate in a future RCT...
September 1, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28914087/effect-of-myofascial-techniques-for-treatment-of-persistent-arm-pain-after-breast-cancer-treatment-randomized-controlled-trial
#5
An De Groef, Marijke Van Kampen, Nele Vervloesem, Evi Dieltjens, Marie-Rose Christiaens, Patrick Neven, Lore Vos, Tessa De Vrieze, Inge Geraerts, Nele Devoogdt
OBJECTIVE: To investigate the effect of myofascial therapy in addition to a standard physical therapy program for treatment of persistent arm pain after finishing breast cancer treatment. DESIGN: Double-blinded (patient and assessor) randomized controlled trial. SETTING: University Hospitals Leuven, Belgium. PATIENTS: A total of 50 patients with persistent arm pain and myofascial dysfunctions after breast cancer treatment...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28912650/the-effects-combining-cryocompression-therapy-following-an-acute-bout-of-resistance-exercise-on-performance-and-recovery
#6
William H DuPont, Brek J Meuris, Vincent H Hardesty, Emily C Barnhart, Landon H Tompkins, Morricia J P Golden, Clayton J Usher, Paul A Spence, Lydia K Caldwell, Emily M Post, Matthew K Beeler, William J Kraemer
Compression and cold therapy used separately have shown to reduce negative effects of tissue damage. The combining compression and cold therapy (cryocompression) as a single recovery modality has yet to be fully examined. To examine the effects of cryocompression on recovery following a bout of heavy resistance exercise, recreationally resistance trained men (n =16) were recruited, matched, and randomly assigned to either a cryocompression group (CRC) or control group (CON). Testing was performed before and then immediately after exercise, 60 minutes, 24 hours, and 48 hours after a heavy resistance exercise workout (barbell back squats for 4 sets of 6 reps at 80% 1RM, 90 sec rest between sets, stiff legged deadlifts for 4 sets of 8 reps at 1...
September 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28899109/book-review-surface-imaginations-cosmetic-surgery-photography-and-skin-surface-imaginations-cosmetic-surgery-photography-and-skin-by-hurst-rebecca-alpha-johnston-montreal-mcgill-queen-s-university-press-2015-xxii-239-pp-32-95-hardcover
#7
https://www.readbyqxmd.com/read/28895154/perceptions-of-pain-of-laryngeal-electromyography
#8
Ashley P O'Connell Ferster, Amanda Hu
OBJECTIVE: To evaluate pain associated with laryngeal electromyography (LEMG). STUDY DESIGN: A prospective case series. METHODS: Adult patients scheduled for LEMG in a tertiary care laryngology practice were recruited between July 20, 2016, and March 1, 2017. Demographic and clinical data were extracted from the charts. Study participants reported their anticipated pain level using a visual analog scale (VAS) prior to the procedure. VAS was administered again within 10 minutes after the procedure, along with the validated McGill Pain Questionnaire, to gauge patient's pain perception after undergoing LEMG...
September 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28893382/pain-and-sensory-disturbances-following-surgical-repair-of-pectus-carinatum
#9
Marie Veje Knudsen, Hans K Pilegaard, Kasper Grosen
BACKGROUND/PURPOSE: The purpose of this study was to assess the characteristics of persistent postoperative pain and sensory disturbances following surgical repair of pectus carinatum. METHODS: Using a prospective observational design, 28 patients were assessed before, 6 weeks and 6 months after a modified Ravitch operation for pectus carinatum. Postoperative pain was assessed using the Short Form McGill Pain Questionnaire. Sensory testing was conducted to detect brush-evoked allodynia and pinprick hyperalgesia...
August 25, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28889054/evaluation-of-chemical-immersion-treatments-to-reduce-microbial-populations-in-fresh-beef
#10
Ahmed Kassem, Joseph Meade, James Gibbons, Kevina McGill, Ciara Walsh, James Lyng, Paul Whyte
The aim of the current study was to assess the ability of a number of chemicals (acetic Acid (AA), citric acid (CA) lactic acid (LA), sodium decanoate (SD) and trisodium phosphate (TSP)) to reduce microbial populations (total viable count, Campylobacter jejuni, Escherichia coli, Salmonella typhimurium and Listeria monocytogenes) on raw beef using an immersion system. The following concentrations of each chemical were used: 3 & 5% for AA, CA, LA, SD and 10 &12% for TSP. Possible synergistic effects of using combinations of two chemicals sequentially (LA+CA and LA+AA) were also investigated...
September 5, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28887855/effects-of-anhydrous-lanolin-versus-breast-milk-combined-with-a-breast-shell-for-the-treatment-of-nipple-trauma-and-pain-during-breastfeeding-a-randomized-clinical-trial
#11
Flaviana Vieira, Dálete Delalibera C F Mota, Thaíla Corrêa Castral, Janaína Valadares Guimarães, Ana Karina Marques Salge, Maria Márcia Bachion
INTRODUCTION: The purpose of this study was to compare the effect of anhydrous lanolin with the effect of breast milk combined with a breast shell for treatment of nipple trauma and pain during breastfeeding. METHODS: A randomized clinical trial was conducted in a maternity ward in a hospital accredited as a Baby-Friendly Hospital located in the middle-western region of Brazil. Breastfeeding women with obvious nipple trauma were randomized into 2 groups. In both groups, breastfeeding education was conducted...
September 9, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28885765/reducing-hospital-acquired-pressure-ulcers-using-bundle-methodology-in-pediatric-and-neonatal-patients-receiving-extracorporeal-membrane-oxygenation-therapy-an-integrative-review-and-call-to-action
#12
Suzanne E Courtwright, Kari A Mastro, Christa Preuster, Navid Dardashti, Sandra McGill, Myrlene Madelon, Donna Johnson
PURPOSE: This review focuses on identifying (1) evidence of the effectiveness of care bundle methodology to reduce hospital-acquired pressure ulcers (HAPUs) in pediatric and neonatal patients receiving extracorporeal membrane oxygenation (ECMO) therapy and (2) barriers to implementing HAPU care bundles in this at-risk population. DESIGN AND METHODS: An integrative review was conducted and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
September 8, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28885126/utility-and-costs-of-radiologist-interpretation-of-perioperative-imaging-in-patients-with-traumatic-single-level-thoracolumbar-fractures
#13
Michael H Weber, Lojan Sivakumaran, Maryse Fortin, Alisson R Teles, Jeff D Golan, Carlo Santaguida, Peter Jarzem, Thierry Pauyo
OBJECTIVE The cost of spine management is rising. As diagnostic imaging accounts for approximately 10% of total patient care spending, there is interest in determining if economies could be made with regard to the routine consultation of radiology for image interpretation. In the context of spine trauma, both the spine surgeon and the radiologist interpret perioperative imaging. Authors of the present study investigated the impact of radiologist interpretation of perioperative imaging from patients with traumatic single-level thoracolumbar fractures given that spine surgeons are expected to be comfortable interpreting pathologies of the musculoskeletal system...
September 8, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28884717/-clinical-and-emotional-behavioral-characteristics-of-acute-and-chronic-low-back-pain
#14
E Z Yakupov, T S Grigoryeva
AIM: To analyze clinical and emotional/behavioral characteristics of acute and chronic low-back pain that significantly affect quality-of-life. MATERIAL AND METHODS: Fifty-three patients with pain syndromes were examined using the painDETECT questionnaire, the Visual Analog Scale for Pain, The McGill Pain Questionnaire and laboratory and instrumental methods of neurological assessment. RESULTS AND CONCLUSION: A 'picture of the patient with acute and chronic pain' was built, a group of patients with neuropathic component of pain was described...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28884227/sleep-quality-in-subjects-suffering-from-chronic-pain
#15
Mohammad Keilani, Richard Crevenna, Thomas Ernst Dorner
BACKGROUND: Sleeping problems are very common in patients with chronic pain. The aim of the study was to investigate the association between different dimensions of chronic pain and sleep quality in chronic pain patients. METHODS: In this cross-sectional interview-based questionnaire study, patients from 3 different pain treatment centers in Vienna aged 18-65 years, with pain lasting 3 months or longer were asked to participate. The association between the short-form McGill pain questionnaire (SF-MPQ) and sleep quality (sleep onset latency, interrupted sleep due to pain, sleep duration and recovering effect of sleep) was assessed...
September 7, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28877953/anti-inflammatory-roles-of-p38%C3%AE-mapk-in-macrophages-are-context-dependent-and-require-il-10
#16
Abbas Raza, Jessica W Crothers, Mahalia M McGill, Gary M Mawe, Cory Teuscher, Dimitry N Krementsov
The p38 MAPK pathway was originally identified as a master regulator of proinflammatory cytokine production by myeloid cells. Numerous drugs targeting this kinase showed promise in preclinical models of inflammatory disease, but so far, none have shown efficacy in clinical trials. The reasons behind this are unclear, but may, in part, be explained by emerging anti-inflammatory functions of this kinase or overly refined selectivity of second-generation pharmacologic inhibitors. Here, we show that p38α signaling in macrophages plays pro- and anti-inflammatory functions in vivo and in vitro, with the outcome depending on the stimulus, output, kinetics, or mode of kinase inhibition (genetic vs...
September 6, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28877697/enhancing-the-get-healthy-information-and-coaching-service-for-aboriginal-adults-evaluation-of-the-process-and-impact-of-the-program
#17
E Quinn, B J O'Hara, N Ahmed, S Winch, B McGill, D Banovic, M Maxwell, C Rissel
BACKGROUND: Non-communicable chronic diseases in Australia contribute to approximately 85% of the total burden of disease; this proportion is greater for Aboriginal communities. The Get Healthy Service (GHS) is effective at reducing lifestyle-based chronic disease risk factors among adults and was enhanced to facilitate accessibility and ensure Aboriginal cultural appropriateness. The purpose of this study is to detail how formative research with Aboriginal communities was applied to guide the development and refinement of the GHS and referral pathways; and to assess the reach and impact of the GHS (and the Aboriginal specific program) on the lifestyle risk factors of Aboriginal participants...
September 6, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28865749/differential-deregulation-of-ngf-and-bdnf-neurotrophins-in-a-transgenic-rat-model-of-alzheimer-s-disease
#18
M Florencia Iulita, M Beatriz Bistué Millón, Rowan Pentz, Lisi Flores Aguilar, Sonia Do Carmo, Simon Allard, Bernadeta Michalski, Edward N Wilson, Adriana Ducatenzeiler, Martin A Bruno, Margaret Fahnestock, A Claudio Cuello
Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are compromised in Alzheimer's disease. However, the causes and temporal (pathology-dependent) evolution of these alterations are not completely understood. To elucidate these issues, we investigated the McGill-R-Thy1-APP transgenic rat, which exhibits progressive intracellular and extracellular amyloid-beta (Aβ) pathology and ensuing cognitive deficits...
August 30, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28865393/pediatric-aortoiliac-injury-following-blunt-abdominal-trauma-a-case-report
#19
Edward Daniele, Alan Coleman, Ben Hirsch, Thomas McGill, John Fitzwater
INTRODUCTION: The most common mechanism of aortic injury involves motor vehicle collisions resulting in aortic disruptions, occurring almost exclusively in the chest. Injury to the abdominal aorta following blunt trauma is nearly twenty times less likely to occur than the thoracic aorta. Because of the low incidence, there are few reports regarding the presentation and repair of these particular injuries, especially in the pediatric population. PRESENTATION OF CASE: We present a case of a 7-year-old boy involved in a high speed motor vehicle accident with an abdominal aorta transection at the aortic bifurcation extending into the left iliac artery...
July 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28859647/blob-ology-and-biology-of-cryo-em-an-interview-with-helen-saibil
#20
Helen R Saibil
Helen Saibil is Bernal Professor of Structural Biology at Birkbeck, University of London. After undergraduate work at McGill University, Canada, Helen moved to London for her PhD at Kings College. After stints at CEA Grenoble and the University of Oxford, she moved to Birkbeck where her lab studies the operation of macromolecular machinery-including molecular chaperones, protein folding/misfolding, and host cell interactions with pathogens. Helen is a Fellow of the Royal Society, Fellow of the Academy of Medical Sciences, and an Honorary Member of both the British Biophysical Society and the Royal Microscopical Society...
August 31, 2017: BMC Biology
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