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multiple scleosis

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1960: Acta Psychiatrica Scandinavica. Supplementum
A M Marmont
Since Morton and Siegel's epochal experiments 30 years ago animal models have been successfully utilized both for transfer and resolution of autoimmune diseases (AID). More recently human lymphocyte xenografts have reproduced clinical AID in SCID mice. Allogeneic stem cell transplantation demonstrated therapeutic potential in fully developed autoimmune disease. Mixed allogeneic chimerism induced by a sublethal approach has also been shown to prevent and even reverse autoimmune insulitis in nonobese diabetic (NOD) mice...
August 1998: Haematologica
A L Leonovich, L S Gitkina
A long-term observation over patients with disseminated scleosis who were treated by glucorticoid hormones demonstrated that hormone therapy with short sessions and a standard scheme appeared to be uneffective. The presentation is based on an examination of 25 patients who had undergone a durative course of hormone therapy with an individual scheme of optimal doses equal to middle ones (30-40 mg of prednisolon) and a selection of maintenance doses used for a long time or with short intervals. Such forms of treatment were more effective...
September 1976: Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova
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