William G Breen, Connie S Geno, Mark R Waddle, Jing Qian, William S Harmsen, Terry C Burns, Ugur T Sener, Michael W Ruff, Bryan J Neth, Joon H Uhm, David M Routman, Elizabeth Yan, Jon J Kruse, Nadia N Laack, Paul D Brown, Anita Mahajan
BACKGROUND: This study aimed to determine whether proton craniospinal irradiation (CSI) decreased the dose to normal tissue and resulted in less toxicity than photon CSI for adult patients. METHODS: This single-institution retrospective analyzed differences in radiation doses, acute toxicity, and cost between proton and CSI for adult medulloblastoma patients. RESULTS: Of 39 total patients, 20 were treated with photon CSI prior to 2015, and 19 were treated with proton CSI thereafter...
2024: Neuro-oncology advances