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Siripanth Nippita, Miriam J Haviland, Sara F Voit, Judith Perez-Peralta, Michele R Hacker, Maureen E Paul
BACKGROUND: High fidelity simulation creates conditions that resemble real circumstances, and can help teach procedures such as intrauterine contraception placement. Its impact on skill retention has not been studied. OBJECTIVE: To evaluate novice learners' skills, attitudes, and knowledge on placement of intrauterine contraception when trained using a high-fidelity commercially available simulator compared with a low-fidelity simulator. STUDY DESIGN: We recruited senior nurse practitioner students and interns in obstetrics and gynecology and family medicine inexperienced with intrauterine contraception placement...
November 11, 2017: American Journal of Obstetrics and Gynecology
Wenchao Du, Wenjuan Tan, Ying Yin, Rong Ji, Jose R Peralta-Videa, Hongyan Guo, Jorge L Gardea-Torresdey
The effects of metallic copper nanoparticles (nCu) in plants are not well understood. In this study, soil grown oregano (Origanum vulgare) was exposed for 60days to nCu and Cu microparticles (μCu) at 0-200mgCu/kg. At harvest, Cu accumulation, biomass production, nutrient composition, and Cu fractions in soil were measured. Except for μCu at 50mg/kg, both nCu and μCu increased root Cu (28.4-116.0%) and shoot Cu (83.0-163.0% and 225.4-652.5%, respectively), compared with control. Copper accumulation from μCu increased as the external μCu increased...
November 10, 2017: Science of the Total Environment
Jesús Gustavo Ponce González, Amelia Guadalupe-Grau, Francisco Germán Rodríguez-González, Rafael Torres-Peralta, David Morales-Alamo, Lorena Rodríguez-García, Bonifacio Nicolás Díaz-Chico, José Antonio López Calbet, Cecilia Dorado
INTRODUCTION: Androgens play a major role in fat oxidation; however, the effects of androgens depend, among other factors, on the intrinsic characteristics of the androgen receptor (AR). Lower repetitions of CAG and GGN polymorphism appear to have a protective effect on fat accumulation in the transition from adolescent to mid-twenties. Whether a similar protective effect is present later in life remains unknown. The aims of this study were: a) to evaluate if extreme CAG and GGN repeat polymorphisms of the androgen receptors influence body fat mass, its regional distribution, resting metabolic rate (RMR), maximal fat oxidation capacity (MFO) and serum leptin, free testosterone and osteocalcin in healthy adult men; and b) to determine the longitudinal effects on fat tissue accumulation after 6...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Jesús de la Fuente, Inmaculada Cubero, Mari Carmen Sánchez-Amate, Francisco J Peralta, Angélica Garzón, Javier Fiz Pérez
The competency for interacting with alcohol is a highly useful Educational Psychology model for preventing and for understanding the different behavioral levels of this interaction. Knowledge of facts, concepts and principles about alcohol use, self-regulated behavior, and attitudes toward alcohol are predictive of adequate interaction with alcohol. The objective of this study was to empirically evaluate this postulated relationship. A total of 328 Spanish adolescents participated, between the ages of 12 and 17...
2017: Frontiers in Psychology
Carmen Vargas-Lagunas, Yolanda Mora, Rafael Díaz, Gabriel Martínez-Batallar, Lourdes Girard, Sergio Encarnación, Humberto Peralta, Jaime Mora
argC encodes N-acetyl-gamma-glutamyl phosphate reductase, the enzyme that catalyzes the high-energy consuming third step in the arginine synthesis pathway. A comparative analysis revealed two translation start sites in argC from Sinorhizobium meliloti. To determine whether both protein versions are synthesized in the organism and their functional role, we obtained genetic constructs with one (1S) or two (2S) start sites, with promoters of low (pspeB) or high (plac) transcriptional rate. The constructs were transferred to the S...
November 7, 2017: FEMS Microbiology Letters
José Pedro Lavrador, Marta Valente Pinto, Luís Mascarenhas Lemos, Catarina Ribeiro, André Peralta Santos
The prognosis of the association between Breast Cancer (BC) and Meningioma (M) is unknown. To evaluate the survival impact of tumor exposure sequence in patients with both tumors. Patients were divided in groups according to the tumors sequence: BC before M (group 1), synchronous BC + M (group 2) and BC after M (group 3). The SEER database was used. Demographics, meningioma and breast cancer variables were analyzed. The primary outcome was oncological survival. A total of 1715 patients were included (median follow-up:84 months)...
November 8, 2017: Journal of Neuro-oncology
Zeyu Peng, Amanda S Parker, Maria D R Peralta, Krishnakumar M Ravikumar, Daniel L Cox, Michael D Toney
We present estimates of ultimate tensile strength (UTS) for two engineered β-solenoid protein mutant fibril structures (spruce budworm and Rhagium inquisitor antifreeze proteins) derived from sonication-based measurements and from force pulling molecular dynamics simulations, both in water. Sonication experiments generate limiting scissioned fibrils with a well-defined length-to-width correlation for the mutant spruce budworm protein and the resultant UTS estimate is 0.66 ± 0.08 GPa. For fibrils formed from engineered R...
November 7, 2017: Biophysical Journal
Caucasella Diaz-Trujillo, Pablo Chong, Ioannis Stergiopoulos, Viviane Cordovez, Mauricio Guzman, Pierre J G M De Wit, Harold J G Meijer, Rafael E Arango Isaza, Gabriel Scalliet, Helge Sierotzki, Esther Lilia Peralta, Gerrit H J Kema
The Dothideomycete Pseudocercospora fijiensis, previously Mycosphaerella fijiensis, is the causal agent of black Sigatoka, one of the most destructive diseases of bananas and plantains. Disease management depends on fungicide applications with a major share for sterol demethylation-inhibitors (DMIs). The continued use of DMIs puts a considerable selection pressure on natural P. fijiensis populations enabling the selection of novel genotypes with reduced sensitivity. The hitherto explanatory mechanism for this reduced sensitivity was the presence of non-synonymous point mutations in the target gene Pfcyp51, encoding the sterol 14α-demethylase enzyme...
November 4, 2017: Molecular Plant Pathology
Gabriela Borrayo Sánchez, Héctor Álvarez Covarrubias, Gilberto Pérez Rodríguez, Efraín Arizmendi Uribe, Erick Ramírez-Arias, Martín Rosas Peralta, Jesús Arriaga Dávila
Objective: To evaluate the impact of the implementation of the Infarction Code strategy in patients with acute myocardial infarction diagnosis. Methods: Consecutive patients with ST-elevation acute myocardial infarction ≤12 hours of evolution, were included in the infarction code strategy, before (Group I) and after (Group II). Times of medical attention and major cardiovascular events during hospitalization were analyzed. Results: 1227 patients were included, 919 men (75%) and 308 women (25%) with an average age of 62 ± 11 years...
2017: Gaceta Médica de México
Manuel J Cuesta, Lucia Moreno-Izco, María Ribeiro, Jose M López-Ilundain, Pablo Lecumberri, Teresa Cabada, Ruth Lorente-Omeñaca, Ana M Sánchez-Torres, M Sol Gómez, Victor Peralta
Motor abnormalities (MAs) may be already evidenced long before the beginning of illness and are highly prevalent in psychosis. However, the extent to which the whole range of MAs are related to cognitive impairment in psychosis remains understudied. This study aimed to examine comparatively the relationships between the whole range of motor abnormalities and cognitive impairments in the first-episode of psychosis (FEP), their unaffected siblings and healthy control subjects. Fifty FEP patients, 21 of their healthy siblings and 24 age- and sex matched healthy controls were included...
October 30, 2017: Schizophrenia Research
Jaqueline Garcia-Silva, Nuria Navarrete Navarrete, Ana Ruano Rodríguez, María Isabel Peralta-Ramírez, Juan Diego Mediavilla García, Vicente E Caballo
BACKGROUND AND OBJECTIVE: Metabolic syndrome (MetS) is a cluster of metabolic conditions that include abdominal obesity, reduction in cholesterol concentrations linked to high density lipoproteins (HLDc), elevated triglycerides, increased blood pressure and hyperglycaemia. Given that this is a multicausal disease, the aim of this study is to identify the psychological, emotional and lifestyle variables that can have an influence on the different MetS components. PATIENTS AND METHODS: A cross-sectional study with 103 patients with diagnostic criteria for MetS (47 male and 56 female)...
October 30, 2017: Medicina Clínica
Bayileyegn A Abate, Rajendra P Joshi, Juan E Peralta
In this work, we generalize the local spin analysis of Clark and Davidson [J. Chem. Phys. 115(16), 7382 (2001)] for the partitioning of the expectation value of molecular spin square operator, 〈S(2)〉, into atomic contributions, 〈SA·SB〉, to the noncollinear spin case in the framework of density functional theory (DFT). We derive the working equations and we show applications to the analysis of the noncollinear spin solutions of typical spin-frustrated systems and to the calculation of magnetic exchange couplings...
November 2, 2017: Journal of Chemical Theory and Computation
Isela García-Gudiño, Eucario Yllescas-Medrano, Rolando Maida-Claros, Diana Soriano-Becerril, Nestor F Díaz, Guadalupe García-López, Anayansí Molina-Hernández, Oscar Flores-Herrera, Francisco J Zavala-Díaz de la Serna, María Del Rosario Peralta-Pérez, Héctor Flores-Herrera
It is estimated that 15% of all newborns admitted to the neonatal intensive care unit (NICU) for suspected sepsis receive multiple broad-spectrum antibiotics without pathogen identification. The gold standard for bacterial sepsis detection is blood culture, but the sensitivity of this method is very low. Recently, amplification and analysis of the 16S ribosomal DNA (rDNA) bacterial gene in combination with denaturing gradient gel electrophoresis (DGGE) has proven to be a useful approach for identifying bacteria that are difficult to isolate by standard culture methods...
October 31, 2017: European Journal of Pediatrics
M Peralta-Mamani, Á Terrero-Pérez, G Dalben, C M F Rubira, H M Honório, I F Rubira-Bullen
The presence of lower lip pits in individuals with Van der Woude syndrome (VWS) may cause discomfort due to saliva secretion. Furthermore, one of the main complaints in relation to lip pits is poor aesthetics, which often affects quality of life. The aim of this systematic review was to identify the best technique for the surgical removal of lower lip pits in terms of aesthetic and functional characteristics. A search of the PubMed, Embase, Web of Science, Science Direct, and Scopus databases was performed on December 27, 2016, which retrieved 88 records without duplicates...
October 28, 2017: International Journal of Oral and Maxillofacial Surgery
Cristina Pantoja Peralta, Ángeles Moreno Gutiérrez, Benet Gómez Moya
No abstract text is available yet for this article.
October 2017: Emergencias
E C Cortés-Peralta, J Ocampo-Candiani, O T Vázquez-Martínez, I M Gutiérrez-Villarreal, I Miranda-Maldonado, V Garza-Rodríguez
BACKGROUND: Histological diagnosis of a clinically suspected nonmelanoma skin cancer (NMSC) is recommended before treatment. For NMSC, concordance between the histological subtype of the preoperative biopsy and the excision specimen of basal cell carcinoma (BCC) has been reported to range from 10% to 81%. No large study on the concordance between NMSC histology seen in a preoperative biopsy with the following tumour specimen from Mohs micrographic surgery (MMS) has been performed in a Latin American population...
October 21, 2017: Actas Dermo-sifiliográficas
Zeyu Peng, Maria D R Peralta, Michael D Toney
The self-assembly of biological molecules into ordered nanostructures is an attractive method for fabricating novel nanomaterials. Nucleic acid-based nanostructures suffer from limitations to functionalization and stability. Alternatively, protein-based nanostructures have advantageous chemical properties, but design facility lags behind that of nucleic acids. Structurally defined fibrils engineered from β-solenoid proteins (BSPs) form under mild conditions [Peralta, M. D. R., et al. (2015) ACS Nano 9, 449-463] and are good candidates for novel nanomaterials because of the defined sequence-to-structure relationship and tunable properties...
November 3, 2017: Biochemistry
Danielle A Ferraguti, Molly McGetrick, Ivan Zendejas, David Hernandez-Gonzalo, Regino Gonzalez-Peralta
Mucinous cystadenomas (MCAs) of the liver (also called hepatic biliary cystadenomas) are rare tumors that comprise about 5% of cystic masses of the liver in adults. These slow-growing lesions most commonly occur in middle-aged individuals, with a female sex predominance. Herein, we present a MCA in a 6-year-old male, one of only very few such cases described in the pediatric literature to date. Although MCAs are generally considered benign lesions, malignant transformation rarely occurs. The recurrence rate is high when partial cyst excision is performed...
2017: Frontiers in Pediatrics
Teresa K Chen, Adrienne Tin, Carmen A Peralta, Lawrence J Appel, Michael J Choi, Michael S Lipkowitz, Cheryl A Winkler, Michelle M Estrella
BACKGROUND AND OBJECTIVES: The natural history of kidney disease among blacks who carry the APOL1 high-risk variants varies, with only a subgroup progressing to ESRD. We aimed to determine whether the APOL1 risk variants are associated with incident proteinuria in the context of hypertension-attributed CKD, and whether subsequent kidney function decline after the onset of proteinuria differs by APOL1 risk status. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using Cox models, we studied the association between APOL1 risk status and incident proteinuria (defined as a doubling of urine protein-to-creatinine ratio to a level ≥0...
November 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
Maged Alotaibi, Sueli Skinner-Ramos, Ali Alamri, Bader Alharbi, Mohammed Alfarraj, Luis Grave de Peralta
Simulations were conducted to explore a broader collection of possible illumination patterns realizable using a white-light-emitting hemispherical digital condenser. Several simple, but practical, illumination patterns were selected and used in experiments where a sample was illuminated simultaneously from different directions. The illumination-direction multiplexing (IDM) Fourier ptychographic microscopy (FPM) method was successfully used for imaging and phase recovery. This study suggests that IDM-FPM can be used for imaging photonic crystals with subwavelength periods using traditional microscope condensers with variable numerical aperture...
May 10, 2017: Applied Optics
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