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https://www.readbyqxmd.com/read/27923782/comparing-arterial-function-parameters-for-the-prediction-of-coronary-heart-disease-events-the-multi-ethnic-study-of-atherosclerosis-mesa
#1
Elizabeth K Hom, Daniel A Duprez, David R Jacobs, David A Bluemke, Lyndia C Brumback, Joseph F Polak, Carmen A Peralta, Philip Greenland, Sheryl L Magzamen, João A C Lima, Alban Redheuil, David M Herrington, James H Stein, Dhananjay Vaidya, Pamela Ouyang, Joel D Kaufman
Arterial dysfunction has been linked to decline in cardiac function and increased risk of cardiovascular disease events. We calculated the value of arterial function, measured at baseline (2000-2002), in predicting time to first coronary heart disease (CHD) event (median follow-up, 10.2 years) among participants in the Multi-Ethnic Study of Atherosclerosis (MESA). Measures included the following: C1 and C2, derived from diastolic pulse contour analysis from the radial artery blood pressure waveform obtained by tonometry (n = 6,336); carotid distensibility and Young's elastic modulus at the carotid artery, derived from carotid artery ultrasonography (n = 6,531 and 6,528); and aortic distensibility, measured using cardiac magnetic resonance imaging (n = 3,677)...
December 6, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27918534/multiethnic-genome-wide-meta-analysis-of-ectopic-fat-depots-identifies-loci-associated-with-adipocyte-development-and-differentiation
#2
Audrey Y Chu, Xuan Deng, Virginia A Fisher, Alexander Drong, Yang Zhang, Mary F Feitosa, Ching-Ti Liu, Olivia Weeks, Audrey C Choh, Qing Duan, Thomas D Dyer, John D Eicher, Xiuqing Guo, Nancy L Heard-Costa, Tim Kacprowski, Jack W Kent, Leslie A Lange, Xinggang Liu, Kurt Lohman, Lingyi Lu, Anubha Mahajan, Jeffrey R O'Connell, Ankita Parihar, Juan M Peralta, Albert V Smith, Yi Zhang, Georg Homuth, Ahmed H Kissebah, Joel Kullberg, René Laqua, Lenore J Launer, Matthias Nauck, Michael Olivier, Patricia A Peyser, James G Terry, Mary K Wojczynski, Jie Yao, Lawrence F Bielak, John Blangero, Ingrid B Borecki, Donald W Bowden, John Jeffrey Carr, Stefan A Czerwinski, Jingzhong Ding, Nele Friedrich, Vilmunder Gudnason, Tamara B Harris, Erik Ingelsson, Andrew D Johnson, Sharon L R Kardia, Carl D Langefeld, Lars Lind, Yongmei Liu, Braxton D Mitchell, Andrew P Morris, Thomas H Mosley, Jerome I Rotter, Alan R Shuldiner, Bradford Towne, Henry Völzke, Henri Wallaschofski, James G Wilson, Matthew Allison, Cecilia M Lindgren, Wolfram Goessling, L Adrienne Cupples, Matthew L Steinhauser, Caroline S Fox
Variation in body fat distribution contributes to the metabolic sequelae of obesity. The genetic determinants of body fat distribution are poorly understood. The goal of this study was to gain new insights into the underlying genetics of body fat distribution by conducting sample-size-weighted fixed-effects genome-wide association meta-analyses in up to 9,594 women and 8,738 men of European, African, Hispanic and Chinese ancestry, with and without sex stratification, for six traits associated with ectopic fat (hereinafter referred to as ectopic-fat traits)...
December 5, 2016: Nature Genetics
https://www.readbyqxmd.com/read/27913169/liquid-nitrogen-pretreatment-of-eucalyptus-sawdust-and-rice-hull-for-enhanced-enzymatic-saccharification
#3
Rafael Castoldi, Vanesa G Correa, Gutierrez Rodrigues de Morais, Cristina G M de Souza, Adelar Bracht, Rosely A Peralta, Regina F Peralta-Muniz Moreira, Rosane M Peralta
In this work, liquid nitrogen was used for the first time in the pretreatment of plant biomasses for purposes of enzymatic saccharification. After treatment (cryocrushing), the initial rates of the enzymatic hydrolysis of eucalyptus sawdust and rice hull were increased more than ten-fold. Cryocrushing did not modify significantly the contents of cellulose, hemicellulose and lignin in both eucalyptus sawdust and rice hulls. However, substantial disorganization of the lignocellulosic materials in consequence of the pretreatment could be observed by electron microscopy...
November 25, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27901070/low-frequency-piezoresonance-defined-dynamic-control-of-terahertz-wave-propagation
#4
Moumita Dutta, Soutik Betal, Xomalin G Peralta, Amar S Bhalla, Ruyan Guo
Phase modulators are one of the key components of many applications in electromagnetic and opto-electric wave propagations. Phase-shifters play an integral role in communications, imaging and in coherent material excitations. In order to realize the terahertz (THz) electromagnetic spectrum as a fully-functional bandwidth, the development of a family of efficient THz phase modulators is needed. Although there have been quite a few attempts to implement THz phase modulators based on quantum-well structures, liquid crystals, or meta-materials, significantly improved sensitivity and dynamic control for phase modulation, as we believe can be enabled by piezoelectric-resonance devices, is yet to be investigated...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27899573/the-ecocyc-database-reflecting-new-knowledge-about-escherichia-coli-k-12
#5
Ingrid M Keseler, Amanda Mackie, Alberto Santos-Zavaleta, Richard Billington, César Bonavides-Martínez, Ron Caspi, Carol Fulcher, Socorro Gama-Castro, Anamika Kothari, Markus Krummenacker, Mario Latendresse, Luis Muñiz-Rascado, Quang Ong, Suzanne Paley, Martin Peralta-Gil, Pallavi Subhraveti, David A Velázquez-Ramírez, Daniel Weaver, Julio Collado-Vides, Ian Paulsen, Peter D Karp
EcoCyc (EcoCyc.org) is a freely accessible, comprehensive database that collects and summarizes experimental data for Escherichia coli K-12, the best-studied bacterial model organism. New experimental discoveries about gene products, their function and regulation, new metabolic pathways, enzymes and cofactors are regularly added to EcoCyc. New SmartTable tools allow users to browse collections of related EcoCyc content. SmartTables can also serve as repositories for user- or curator-generated lists. EcoCyc now supports running and modifying E...
November 28, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27896278/lack-of-association-between-slc30a8-variants-and-type-2-diabetes-in-mexican-american-families
#6
Hemant Kulkarni, Manju Mamtani, Juan Manuel Peralta, Vincent Diego, Thomas D Dyer, Harald Goring, Laura Almasy, Michael C Mahaney, Sarah Williams-Blangero, Ravindranath Duggirala, Joanne E Curran, John Blangero
SLC30A8 encodes zinc transporter 8 which is involved in packaging and release of insulin. Evidence for the association of SLC30A8 variants with type 2 diabetes (T2D) is inconclusive. We interrogated single nucleotide polymorphisms (SNPs) around SLC30A8 for association with T2D in high-risk, pedigreed individuals from extended Mexican American families. This study of 118 SNPs within 50 kb of the SLC30A8 locus tested the association with eight T2D-related traits at four levels: (i) each SNP using measured genotype approach (MGA); (ii) interaction of SNPs with age and sex; (iii) combinations of SNPs using Bayesian Quantitative Trait Nucleotide (BQTN) analyses; and (iv) entire gene locus using the gene burden test...
2016: Journal of Diabetes Research
https://www.readbyqxmd.com/read/27885108/increasing-our-advocacy-capacity-through-hiv-community-mobilization-perspectives-from-emerging-and-mid-career-professionals
#7
Irene Ovalle, Oralia Loza, David Peralta-Torres, Jacob Martinez, Kristen Hernandez, Holly Mata
In this commentary, six public health practitioners and researchers discuss how their participation in the El Paso HIV Community Mobilization effort has contributed to their professional development and increased their collective capacity to advocate for practice and policy improvements that contribute to health equity in general and within the context of HIV prevention. Like previous commentaries in this department that have highlighted the value of the Certified Health Education Specialist credential (http://www...
November 23, 2016: Health Promotion Practice
https://www.readbyqxmd.com/read/27877210/in-vivo-antitumor-effect-of-an-hpv-specific-promoter-driving-il-12-expression-in-an-hpv-16-positive-murine-model-of-cervical-cancer
#8
Victor Hugo Bermúdez-Morales, Geny Fierros-Zarate, Celina García-Meléndrez, Juan Manuel Alcocer-Gonzalez, Ausencio Morales-Ortega, Oscar Peralta-Zaragoza, Kirvis Torres-Poveda, Ana Isabel Burguete-García, Eva Hernández-Márquez, Vicente Madrid-Marina
Human papillomavirus (HPV) is a DNA virus that infects epithelial cells and has been implicated in the development of cervical cancer. Few therapeutic strategies have been designed for the treatment of cervical intraepithelial neoplasia, a precursor of cervical cancer. In these early stages, the HPV E2 protein is the most important viral factor involved in viral gene expression and plays crucial roles during the vegetative viral cycle in epithelial cells. Papillomavirus E2 binds specifically to palindromic ACCN6GGT sequences, referred to as the E2 binding sites (E2BS), which are concentrated within the viral long control region, and which are responsible for regulation of the HPV protein's expression...
2016: Journal of Cancer
https://www.readbyqxmd.com/read/27875909/high-hiv-trypanosoma-cruzi-coinfection-levels-in-vulnerable-populations-in-buenos-aires-argentina
#9
Andres Benchetrit, Guadalupe Andreani, Maria Mercedes Avila, Diana Rossi, Ana Maria De Rissio, Mercedes Weissenbacher, Liliana Martinez Peralta, Guillermina Dolcini
The coinfection with Trypanosoma cruzi (T. cruzi) and HIV is a relevant clinical event. The goal of this study was to establish the frequency of coinfection in populations at risk for HIV-1 in Argentina. A total of 280 HIV positive serum samples from HIV seroprevalence studies in HIV at-risk groups were tested for T.cruzi infection. Of those samples, 8 were positive for T. cruzi (coinfection rate: 2.9%); 6 of them came from HIV positive injecting drug users (IDUs) (rate: 7.8%). In view of these results, all HIV infected patients in endemic countries should undergo T...
November 22, 2016: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27869413/humoral-immunity-to-tetanus-measles-and-rubella-in-children-with-acute-lymphoblastic-leukemia-after-chemotherapy
#10
Myriam Onorateli, Claudia Botana, Laura Peralta, Magali Rebollo, Silvina Ruvinsky, Myriam Guitter, Maria S Felice, Mercedes Posadas, Silvina Evangelista, Maria V Villar, Mariana Golluscio, Agustina Molina, Lidia Fraquelli
Chemotherapy regimens and clinical support advances have improved survival in children with acute lymphoblastic leukemia. The after-effects of treatment are a reason for concern, including damage to the immune system induced by immunosuppressive therapy which is reflected in the loss of antibody protection provided by prior immunizations. Our goal was to assess the presence of measles, rubella, and tetanus protective antibody titers among patients with acute lymphoblastic leukemia after completing chemotherapy...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27859031/non-random-food-web-assembly-at-habitat-edges-increases-connectivity-and-functional-redundancy
#11
Guadalupe Peralta, Carol M Frost, Raphael K Didham, Tatyana A Rand, Jason M Tylianakis
Habitat fragmentation dramatically alters the spatial configuration of landscapes, with the creation of artificial edges affecting community structure and dynamics. Despite this, it is not known how the different food webs in adjacent habitats assemble at their boundaries. Here we demonstrate that the composition and structure of herbivore-parasitoid food webs across edges between native and plantation forests are not randomly assembled from those of the adjacent communities. Rather, elevated proportions of abundant, interaction-generalist parasitoid species at habitat edges allowed considerable interaction rewiring, which led to higher linkage density and less modular networks, with higher parasitoid functional redundancy...
November 14, 2016: Ecology
https://www.readbyqxmd.com/read/27857888/the-triple-q-algorithm-a-practical-approach-to-the-identification-of-liver-topography
#12
Omar Bekdache, Ahmad Zarour, Ayman El-Menyar, Yassir Abdulrahman, Husham Abdelrahman, Mohammad Ellabib, Ruben Peralta, Hassan Al-Thani
The descriptive identification and interpretation of liver pathology continue to raise debate, especially for trainees and junior physicians. There is wide diversity in the description of liver segmentation with sometimes contradictory terminology between French and American literature. Attempts were made to create a unified nomenclature that simplifies the problem. We propose a simple approach to describe the location of liver pathology in different settings by referring to an algorithm based on three questions...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27855309/evidence-of-an-epistatic-effect-between-dysbindin-1-and-neuritin-1-genes-on-the-risk-for-schizophrenia-spectrum-disorders
#13
C Prats, B Arias, J Moya-Higueras, E Pomarol-Clotet, M Parellada, A González-Pinto, V Peralta, M I Ibáñez, M Martín, L Fañanás, M Fatjó-Vilas
BACKGROUND: The interest in studying gene-gene interactions is increasing for psychiatric diseases such as schizophrenia-spectrum disorders (SSD), where multiple genes are involved. Dysbindin-1 (DTNBP1) and Neuritin-1 (NRN1) genes have been previously associated with SSD and both are involved in synaptic plasticity. We aimed to study whether these genes show an epistatic effect on the risk for SSD. METHODS: The sample comprised 388 SSD patients and 397 healthy subjects...
November 14, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/27850081/441-bedside-ultrasound-training-for-university-of-missouri-internal-medicine-residents
#14
Tabitha Ku, Julie Alexander, Joseph Puetz, Tushar Tarun, Devin Kennedy, Angel Peralta, Harjyot Sohal
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27836330/evaluation-of-rosemont-criteria-for-non-calcific-chronic-pancreatitis-nccp-based-on-histopathology-a-retrospective-study
#15
Guru Trikudanathan, Satish Munigala, Usman Barlass, Ahmad Malli, Yusheng Han, Miroslav Sekulic, Melena Bellin, Srinath Chinnakotla, Ty Dunn, Timothy Pruett, Gregory Beilman, Jose-Vega Peralta, Mustafa Arain, Stuart Amateau, Shawn Mallery, Martin L Freeman, Rajeev Attam
BACKGROUND: Rosemont classification for chronic pancreatitis has not been evaluated specifically in non-calcific chronic pancreatitis (NCCP) patients and to this date, it has not been correlated with the gold standard namely histopathology. OBJECTIVE: To assess the correlation of EUS Rosemont criteria for NCCP with histopathology from surgical specimens and evaluate the impact of age, sex, BMI, smoking and alcohol on Rosemont classification. METHODS: Adult patients undergoing TPIAT for NCCP between July 2009 and January 2013 were identified from our institutional database...
October 26, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/27833604/genomic-comparison-of-agrobacterium-pusense-strains-isolated-from-bean-nodules
#16
Alejandro Aguilar, Humberto Peralta, Yolanda Mora, Rafael Díaz, Carmen Vargas-Lagunas, Lourdes Girard, Jaime Mora
No abstract text is available yet for this article.
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27833125/photo-electrons-unveil-topological-transitions-in-graphene-like-systems
#17
Lucila Peralta Gavensky, Gonzalo Usaj, C A Balseiro
The topological structure of the wavefunctions of particles in periodic potentials is characterized by the Berry curvature Ωkn whose integral on the Brillouin zone is a topological invariant known as the Chern number. The bulk-boundary correspondence states that these numbers define the number of edge or surface topologically protected states. It is then of primary interest to find experimental techniques able to measure the Berry curvature. However, up to now, there are no spectroscopic experiments that proved to be capable to obtain information on Ωkn to distinguish different topological structures of the bulk wavefunctions of semiconducting materials...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27831609/-psychometric-properties-of-the-third-version-of-family-adaptability-and-cohesion-evaluation-scales-faces-iii-a-study-of-peruvian-adolescents
#18
Juan Carlos Bazo-Alvarez, Oscar Alfredo Bazo-Alvarez, Jeins Aguila, Frank Peralta, Wilfredo Mormontoy, Ian M Bennett
Objetives.: Our aim was to evaluate the psychometric properties of the FACES-III among Peruvian high school students. Materials and Methods.: This is a psychometric cross-sectional study. A probabilistic sampling was applied, defined by three stages: stratum one (school), stratum two (grade) and cluster (section). The participants were 910 adolescent students of both sexes, between 11 and 18 years of age. The instrument was also the object of study: the Olson's FACES-III...
July 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/27828900/multicolor-scanning-laser-imaging-in-lipemia-retinalis
#19
David Rivera-De La Parra, Liliana Perez-Peralta, Jim Toldi, Jason Levine, Michael Fikhman, Enrique O Graue-Hernandez
PURPOSE: To describe multicolor scanning laser imaging (MSLI) and conventional fundus photography findings in lipemia retinalis (LR). METHODS: We report two LR cases. The first case is a 47-year-old diabetic woman with LR secondary to familial hypertriglyceridemia examined with MSLI, conventional fundus photography, and optical coherence tomography (OCT). The second case is a 39-year-old diabetic man with hypertriglyceridemia and LR. He was followed over time with conventional fundus photography of his retina until metabolic control was achieved...
November 8, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27825484/acanthamoeba-spp-as-a-universal-host-for-pathogenic-microorganisms-one-bridge-from-environment-to-host-virulence
#20
REVIEW
Allan J Guimaraes, Kamilla Xavier Gomes, Juliana Reis Cortines, José Mauro Peralta, Regina H Saramago Peralta
Free-living amoebas (FLA) are ubiquitous environmental protists that have enormously contributed to the microbiological contamination of water sources. FLAs have displayed resistance to environmental adversities and germicides and have played important roles in the population control of microbial communities due to its predatory behavior and microbicidal activity. However, some organisms have developed resistance to the intracellular milieu of amoebas, as in the case of Acanthamoebas, which in turn, have been functioning as excellent reservoirs for amoeba-resistant microorganisms (ARMs), such as bacteria, viruses and fungi...
December 2016: Microbiological Research
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