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Michelle Turcotte, Arkan Abadi, Jesus Peralta-Romero, Fernando Suarez, Hudson Reddon, Jaime Gomez-Zamudio, Ana I Burguete-Garcia, Miguel Cruz, David Meyre
BACKGROUND/OBJECTIVES: The prevalence of abdominal obesity in Mexican children has risen dramatically in the past decade. Genome-wide association studies (GWAS) for waist-to-hip ratio (WHR) performed predominantly in European descent adult  populations have identified multiple single-nucleotide polymorphisms (SNPs) with larger effects in women. The contribution of these SNPs to WHR in non-European children is unknown. SUBJECTS/METHODS: Mexican children and adolescents (N = 1421, 5-17 years) were recruited in Mexico City...
March 13, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Eduardo Hernández-Vázquez, Sandra Young-Peralta, Litzia Cerón-Romero, Sara García-Jiménez, Samuel Estrada-Soto
OBJECTIVES: To explore the antihyperglycaemic and antidiabetic effects and to determine the acute toxicity of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (ENP-9). METHODS: The antihyperglycaemic effect of ENP-9 (50 mg/kg) was determined by oral glucose tolerance test (OGTT). Also, the acute (16, 50 and 160 mg/kg) and subacute (50 mg/kg/day for 10 days) antidiabetic effects of ENP-9 were determined. After subacute treatment, blood samples were analysed to determine glucose and lipid profiles...
May 17, 2018: Journal of Pharmacy and Pharmacology
Aline Cristine da Silva de Souza, Geferson de Almeida Gonсalves, Andréia Assunсão Soares, Anacharis B de Sá-Nakanishi, Ana Paula de Santi-Rampazzo, Maria Raquel Marсal Natali, Rosane Marina Peralta, Adelar Bracht
The purpose of this study was to evaluate possible effects of the administration of an aqueous Agaricus brasiliensis extract on the oxidative state of the liver, brain, and plasma in adjuvant-induced arthritic rats, a model for human rheumatoid arthritis. Daily doses of 400 mg · kg-1 were administered by gavage for 23 days. This treatment produced significant diminutions in protein carbonylation and lipid damage in the liver, brain, and plasma. It also diminished the tissue reactive oxygen species and increased the antioxidant capacity of the plasma...
2018: International Journal of Medicinal Mushrooms
Hsin Yen Liu, Akram Alyass, Arkan Abadi, Jesus Peralta-Romero, Fernando Suarez, Jaime Gomez-Zamudio, Astride Audirac, Esteban J Parra, Miguel Cruz, David Meyre
BACKGROUND/OBJECTIVES: Mexico has one of the highest prevalence of childhood obesity in the world. Genome-wide association studies (GWAS) for obesity have identified multiple single-nucleotide polymorphisms (SNPs) in populations of European, East Asian, and African descent. The contribution of these loci to obesity in Mexican children is unclear. We assessed the transferability of 98 obesity loci in Mexican children and fine-mapped the association signals. SUBJECTS/METHODS: The study included 405 and 390 Mexican children with normal weight and obesity...
March 12, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Adilson Marques, Miguel Peralta, Hugo Sarmento, João Martins, Miguel González Valeiro
Background: This study aimed to assess cross-sectional and prospective relationships between vigorous physical activity (VPA) and the risk of major chronic diseases among European older adults. Methods: Participants were 37 524 older adults who responded to the fourth (in 2011) and fifth (in 2013) wave of the SHARE project, from 13 European countries. Participants answered interview questions about the presence of chronic conditions and VPA. The cross-sectional and prospective association between PA and the number of chronic diseases was assessed using logistic regression models...
May 14, 2018: European Journal of Public Health
Deepika Sirohi, Charlie Vaske, Zack Sanborn, Steven C Smith, Michelle D Don, Kathryn G Lindsey, Scot Federman, Mahesha Vankalakunti, Jamie Koo, Shikha Bose, Mariza de Peralta-Venturina, Jessica van Ziffle, James P Grenert, Steve Miller, Charles Chiu, Mahul B Amin, Jeffry P Simko, Bradley A Stohr, Daniel J Luthringer
In recent years, there has been increased interest in carcinomas of the urologic tract, that demonstrate association with the polyoma virus BK arising in immunosuppressed individuals, though the nature of this association is uncertain. To begin to understand this phenomenon, we reviewed the clinical, morphological, and immunohistochemical features of 11 carcinomas of the urologic tract, mainly urothelial (N = 9) and collecting duct carcinomas (N = 2), occurring during immunosuppression, and expressing polyoma virus T-antigen by immunohistochemistry...
May 15, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Victor Contreras, Ricardo Valencia, Jairo Peralta, H Sobral, M A Meneses-Nava, Horacio Martinez
Laser-induced breakdown spectroscopy is presented for trace element detection of liquid samples by analyzing a single droplet levitated by ultrasonic waves. A single liquid droplet is placed in the node of a standing acoustic wave produced by a uniaxial levitator for further chemical analysis. The acoustic levitator consists of a commercial Langevin-type transducer, attached to a concave mechanical amplifier, and a concave reflector. A micro-syringe was used to manually place individual liquid droplet samples in the acoustic levitation system...
May 15, 2018: Optics Letters
Esmeralda G Blanco-Enríquez, Francisco Javier Zavala-Díaz de la Serna, María Del Rosario Peralta-Pérez, Lourdes Ballinas-Casarrubias, Iván Salmerón, Héctor Rubio-Arias, Beatriz A Rocha-Gutiérrez
Pollution of freshwater ecosystems from polycyclic aromatic hydrocarbons (PAHs) is a global concern. The US Environmental Protection Agency (EPA) has included the PAHs pyrene, phenanthrene, and naphthalene among the 16 priority compounds of special concern for their toxicological effects. The aim of this study was to adapt and characterize a microbial consortium from ore waste with the potential to remove these three PAHs from water. This microbial consortium was exposed to the target PAHs at levels of 5, 10, 20, 50, and 100 mg L−1 for 14 days...
May 13, 2018: International Journal of Environmental Research and Public Health
Borja Romero-González, Rafael Arcangel Caparrós-González, Helen Strivens Vilchez, María Isabel Peralta-Ramírez
INTRODUCTION: pregestational Body Mass Index (BMI) affects mother's health during and after pregnancy and is related to negative outcomes such as low birth weight and preterm birth. Higher pregestational BMI may increase anxiety, stress and depression. OBJECTIVES: to assess potential differences on stress, psychopathological symptoms and physiological variables during pregnancy, among pregnant women with normal pregestational BMI rates and high pregestational BMI rates...
March 1, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Jesús Manuel Morán López, Miriam Hernández González, David Peñalver Talavera, María Peralta Watt, José Luis Temprano Ferreras, Cristina Redondo Llorente, María Yolanda Rubio Blanco
INTRODUCTION: Disease-related malnutrition (DRM) is highly prevalent in Spanish hospitals (occurring in 1 out of every 4 patients). The 'Más Nutridos' Alliance has developed an action plan to detect and treat DRM. In Extremadura (Spain), the public health system has included nutritional screening as the only mechanism to fight malnutrition. The results of this strategy are evaluated here. PATIENTS AND METHODS: An agreement study was conducted in standard clinical practice...
May 8, 2018: Endocrinología, Diabetes y Nutrición
María Inés Alvarez Echazú, Christian Ezequiel Olivetti, Ignacio Peralta, Maria Rosario Alonso, Claudia Anesini, Claudio Javier Perez, Gisela Solange Alvarez, Martin Federico Desimone
A detailed study of biomaterials is mandatory to comprehend their feasible biomedical applications in terms of drug delivery and tissue regeneration. Particularly, mucoadhesive biopolymers such as chitosan (chi) and carboxymethylcellulose (CMC) have become interesting biomaterials regards to their biocompatibility and non-toxicity for oral mucosal drug delivery. In this work, pH-responsive biopolymer-silica composites (Chi-SiO2 , Chi-CMC-SiO2 ) were developed. These two types of composites presented a different swelling behavior due to the environmental pH...
May 7, 2018: Colloids and Surfaces. B, Biointerfaces
Miguel Peralta, João Martins, Francisco Gómez Chávez, Paola Cortés Almanzar, Adilson Marques
BACKGROUND: Physical activity and self-rated wellbeing have important benefits to health. However, scientific knowledge regarding their relationship among older adults is scarce. Thus, the aim of this study was to examine the associations between physical activity frequency and several dimensions of self-rated wellbeing, in a representative sample of European older adults from 28 countries. METHODS: This study is based on the European Social Survey round 6, 2012...
May 8, 2018: European Journal of Sport Science
David Peralta
Exciting changes: Editor David Peralta presents some changes to the ChemMedChem Editorial Board and International Advisory Board. Learn about the new board members in their biographies featured here. Also discussed are our new stance on preprint servers and our upcoming Special Issues, Virtual Issues, and exciting conferences the journal is supporting.
May 8, 2018: ChemMedChem
Krista A McCoy, Ariane L Peralta
No abstract text is available yet for this article.
2018: Frontiers in Microbiology
Luis D Arreola-Peralta, Frida Altamirano-Reyna, Deni M Galindo-González, Jessica G Solis-Anguiano, Enza Lacivita, Marcello Leopoldo, José A Terrón
A decrease in the activation threshold of primary sensory neurons to transient receptor potential V1 (TRPV1) stimulation by serotonin 5-HT7 receptors has been reported but no confirmation if this might translate into facilitation of neurogenic inflammation has been provided. We analysed the modulation of capsaicin (CAP)-induced neurogenic inflammation in the rat hind paw by the selective 5-HT7 receptor agonist, LP-44, and the involvement of calcitonin gen-related peptide (CGRP) in this effect. Animals received intra-plantar injections (30 μl) of vehicle, CAP (0...
May 3, 2018: Peptides
Sean F Mungovan, Paula J Peralta, Gregory C Gass, Aaron T Scanlan
OBJECTIVES: To examine the test-retest reliability and criterion validity of a high-intensity, netball-specific fitness test. DESIGN: Repeated measures, within-subject design. METHODS: Eighteen female netball players competing in an international competition completed a trial of the Net-Test, which consists of 14 timed netball-specific movements. Players also completed a series of netball-relevant criterion fitness tests. Ten players completed an additional Net-Test trial one week later to assess test-retest reliability using intraclass correlation coefficient (ICC), typical error of measurement (TEM), and coefficient of variation (CV)...
April 12, 2018: Journal of Science and Medicine in Sport
Salvador Alcocer, Alain Picos, Agustín R Uribe, Tzayam Pérez, Juan M Peralta-Hernández
Comparative degradation of the industrial dyes Blue BR, Violet SBL and Brown MF 50 mg L-1 has been studied by the electrochemical oxidation (EOx), electro-Fenton (EF), photoelectro-Fenton (PEF) process based on BDD electrode. Each dye was tested in 0.05 mM Na2 SO4 with 0.5 mM Fe2+ at pH 3.0, and electrolyzed in a stirred tank reactor under galvanostatic conditions with 2.0, 5.0, 7.0, 11.0 and 18.0 mA cm-2 . Dyes were oxidized via hydroxyl radicals (OH) formed at the BDD anode from water oxidation coupled with Fenton's reaction cathodically produced hydrogen peroxide (H2 O2 )...
April 27, 2018: Chemosphere
Mariana Yumi Miyadahira, Maria de Lourdes Brizot, Mário Henrique Burlacchini de Carvalho, Sckarlet Ernandes Biancolin, Rita de Cássia Alam Machado, Vera Lúcia Jornada Krebs, Rossana Pulcineli Vieira Francisco, Cleisson Fábio Andrioli Peralta
OBJECTIVES: To describe the perinatal outcomes of type II and III selective fetal growth restriction (sFGR) in monochorionic-diamniotic (MCDA) twin pregnancies treated with expectant management or laser ablation of placental vessels (LAPV). METHODS: Retrospective analysis of cases of sFGR that received expectant management (type II, n=6; type III, n=22) or LAPV (type II, n=30; type III, n=9). The main outcomes were gestational age at delivery and survival rate. RESULTS: The smaller fetus presented an absent/reversed "a" wave in the ductus venosus (arAWDV) in all LAPV cases, while none of the expectant management cases presented arAWDV...
2018: Clinics
Stephen Sarria, Thomas G Bartholow, Adam Verga, Michael D Burkart, Pamela Peralta-Yahya
Medium-chain fatty acids (MCFAs) are key intermediates in the synthesis of medium-chain chemicals including α-olefins and dicarboxylic acids. In bacteria, microbial production of MCFAs is limited by the activity and product profile of fatty acyl-ACP thioesterases. Here, we engineer a heterologous bacterial medium-chain fatty acyl-ACP thioesterase for improved MCFA production in Escherichia coli. Electrostatically matching the interface between the heterologous medium-chain Acinetobacter baylyi fatty acyl-ACP thioesterase (AbTE) and the endogenous E...
May 3, 2018: ACS Synthetic Biology
Daniela S Arroyo, Emilia A Gaviglio, Javier M Peralta Ramos, Claudio Bussi, Maria P Avalos, Liliana M Cancela, Pablo Iribarren
Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from Staphylococcus aureus, in vitro and in vivo , induced microglial cell activation followed by autophagy induction. In this report, we evaluated if phosphatidyl-inositol-3 kinase (PI3K) pharmacological inhibitors LY294200 and 3-methyladenine (3-MA) can modulate the innate immune response to PGN in the central nervous system...
2018: Frontiers in Immunology
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