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https://www.readbyqxmd.com/read/28822255/malnutrition-in-postacute-geriatric-care-basic-espen-diagnosis-and-etiology-based-diagnoses-analyzed-by-length-of-stay-in-hospital-mortality-and-functional-rehabilitation-indexes
#1
Dolores Sánchez-Rodríguez, Ester Marco, Cédric Annweiler, Natalia Ronquillo-Moreno, Andrea Tortosa, Olga Vázquez-Ibar, Ferran Escalada, Xavier Duran, Josep M Muniesa
OBJECTIVE: To determine the relationships between malnutrition and nutrition-related conditions according to the European Society of Clinical Nutrition and Metabolism (ESPEN) consensus and guidelines and clinical outcomes in postacute rehabilitation. METHODS: Of 102 eligible inpatients, 95 (84.5 years old, 63.2% women) fulfilled inclusion criteria: aged ≥70 years, body mass index <30kg/m(2), admission for rehabilitation. Mini-Nutritional Assessment-Short Form (MNA-SF≤11) identified patients "at risk" and ESPEN basic and etiology based definitions were applied...
August 2, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28822233/obese-fathers-lead-to-an-altered-metabolism-and-obesity-in-their-children-in-adulthood-review-of-experimental-and-human-studies
#2
REVIEW
Fernanda Ornellas, Priscila V Carapeto, Carlos A Mandarim-de-Lacerda, Marcia B Aguila
OBJECTIVE: To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. SOURCES: A non-systematic review in the PubMed database found few publications in which paternal obesity was implicated in the adverse transmission of characteristics to offspring. Specific articles on epigenetics were also evaluated. As the subject is recent and still controversial, all articles were considered regardless of year of publication...
August 16, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28822064/evolution-of-29-anthropometric-nutritional-and-cardiometabolic-parameters-among-morbidly-obese-adolescents-2-years-post-sleeve-gastrectomy
#3
Wahiba Elhag, Walid El Ansari, Sama Abdulrazzaq, Ali Abdullah, Mohamed Elsherif, Israa Elgenaied
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a popular treatment for adolescent morbid obesity. Research on LSG outcomes among adolescents assessed a narrow range of anthropometric, nutritional, or cardiometabolic parameters, leading to an incomplete picture of these changes. We examined a wide variety of anthropometric, nutritional, and cardiometabolic parameters among adolescents before and after LSG. METHODS: We retrospectively reviewed medical charts of all obese adolescents who underwent LSG at Hamad Medical Corporation, Qatar, between January 2011 and June 2015 (N = 102)...
August 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28822052/bariatric-surgery-worldwide-baseline-demographic-description-and-one-year-outcomes-from-the-second-ifso-global-registry-report-2013-2015
#4
Richard Welbourn, Dimitri J Pournaras, John Dixon, Kelvin Higa, Robin Kinsman, Johan Ottosson, Almino Ramos, Bart van Wagensveld, Peter Walton, Rudolf Weiner, Natan Zundel
BACKGROUND: Five International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) surveys since 1998 have estimated the volume and type of bariatric surgery being done in constituent member countries. These reports did not include baseline demographic descriptions. METHODS: An IFSO Global Registry pilot project in 2014 demonstrated that it was possible to amalgamate large numbers of individual patient data from different local and national database systems...
August 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28822046/body-mass-index-and-clinical-response-to-intravenous-or-subcutaneous-abatacept-in-patients-with-rheumatoid-arthritis
#5
Maria-Antonietta D'Agostino, Rieke Alten, Eduardo Mysler, Manuela Le Bars, June Ye, Bindu Murthy, Julia Heitzmann, Radu Vadanici, Gianfranco Ferraccioli
This post hoc analysis of ACQUIRE (NCT00559585) explored the effect of baseline body mass index (BMI) on the pharmacokinetics of and clinical response to subcutaneous (SC) or intravenous (IV) abatacept in patients with rheumatoid arthritis (RA). ACQUIRE was a phase 3b, 6-month, double-blind, double-dummy study in which patients with RA were randomized (1:1) to SC (fixed - dose; 125 mg/week) or IV (weight-tiered; ~ 10 mg/kg/month) abatacept plus methotrexate. In this analysis, minimum abatacept plasma concentration (Cmin) was measured at 3 and 6 months, and clinical remission over 6 months was assessed by Disease Activity Score 28 (C-reactive protein; DAS28 [CRP], < 2...
August 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28822025/cardiovascular-health-in-st-louis-bosnian-americans
#6
Maximillian T Bourdillon, Asad S Akhter, Dejan Vrtikapa, Amer Avdagic, Marc A McNeese, Richard Lee, Dawn S Hui
In Bosnia and Herzegovina, cardiovascular disease accounts for nearly 50% of deaths. Cardiovascular health of resettled Bosnian-Americans has not been well-characterized. Our study aimed to quantify cardiovascular risk in Bosnian-Americans in St. Louis, the largest non-European center of resettlement. Seven community screenings focused on Bosnian-Americans were held. Cardiovascular risk was calculated to stratify individuals into low (<10%), moderate (10-20%), and high (>20%) risk. Those with self-reported coronary heart disease (CHD) or risk equivalent were considered high-risk...
August 18, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28822023/pulse-contour-derived-cardiac-output-measurements-in-morbid-obesity-influence-of-actual-ideal-and-adjusted-bodyweight
#7
Chantal A Boly, Pieter Schraverus, Floris van Raalten, Jan-Willem Coumou, Christa Boer, Simone van Kralingen
The non-invasive Nexfin cardiac output (CO) monitor shows a low level of agreement with the gold standard thermodilution method in morbidly obese patients. Here we investigate whether this disagreement is related to excessive bodyweight, and can be improved when bodyweight derivatives are used instead. We performed offline analyses of cardiac output recordings of patient data previously used and partly published in an earlier study by our group. In 30 morbidly obese patients (BMI > 35 kg/m(2)) undergoing laparoscopic gastric bypass, cardiac output was simultaneously determined with PiCCO thermodilution and Nexfin pulse-contour method...
August 18, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28822021/morus-nigra-and-its-major-phenolic-syringic-acid-have-antidepressant-like-and-neuroprotective-effects-in-mice
#8
Ana Paula Dalmagro, Anderson Camargo, Ana Lúcia Bertarello Zeni
Depression is a disorder with a high incidence that has been increasing worldwide although the pathophysiology remains unclear. Moreover, some studies revealed a higher concentration of glutamate and oxidative stress in the patients' brain, which causes cell death by excitotoxicity. Morus nigra L. is known as black mulberry and its leaves are popularly used to treat affections related to menopause, obesity and high cholesterol. M. nigra leaves are a rich fount of phenolics which well-known by the antioxidant property...
August 18, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28821939/analgesic-use-in-patients-with-knee-and-or-hip-osteoarthritis-referred-to-an-outpatient-center-a-cross-sectional-study-within-the-amsterdam-osteoarthritis-cohort
#9
Jesper Knoop, Joyce van Tunen, Martin van der Esch, Leo D Roorda, Joost Dekker, Marike van der Leeden, Willem F Lems
Although analgesics are widely recommended in current guidelines, underuse and inadequate prescription of analgesics seem to result in suboptimal treatment effects in patients with knee and/or hip osteoarthritis (OA). This study aimed (i) to describe the use of analgesics; and (ii) to determine factors that are related to analgesic use in patients with knee and/or hip OA referred to an outpatient center. A cross-sectional study with data from 656 patients with knee and/or hip OA referred to an outpatient center (Amsterdam Osteoarthritis (AMS-OA) cohort) was conducted...
August 18, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28821888/risk-factors-for-epistaxis-in-patients-followed-in-general-practices-in-germany
#10
D U Seidel, L Jacob, K Kostev, A M Sesterhenn
<p>BACKGROUND: The goal of the present study was to analyze the risk factors for epistaxis in patients followed in general practices in Germany.</p> <p>METHODS: The current study sample included patients aged 18 years or older who received a first epistaxis diagnosis between January 2012 and December 2016 (index date). Epistaxis patients and controls without epistaxis were matched (1:1) on the basis of age, gender, insurance status and physician. </p> <p>RESULTS: A total of 16,801 patients with epistaxis and 16,801 control subjects were included in this study...
August 19, 2017: Rhinology
https://www.readbyqxmd.com/read/28821853/visceral-adiposity-index-is-strongly-associated-with-hyperuricemia-independently-of-metabolic-health-and-obesity-phenotypes
#11
Huimin Dong, Yang Xu, Xiuzhi Zhang, Simiao Tian
Visceral adiposity index (VAI) is a novel sex-specific index for visceral adipose function; however the association between VAI and hyperuricemia in China is unknown. We aimed to investigate this association, also whether it was independent of metabolic health and obesity phenotypes. 7632 adult subjects from the China Health and Nutrition Survey 2009 were retained. Subjects were categorized into four obesity phenotypes based on a cross-classification of BMI and metabolic health status by two representative criteria...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821741/predicting-the-murine-enterocyte-metabolic-response-to-diets-that-differ-in-lipid-and-carbohydrate-composition
#12
Neeraj Sinha, Maria Suarez-Diez, Evert M van Schothorst, Jaap Keijer, Vitor A P Martins Dos Santos, Guido J E J Hooiveld
The small intestine serves as gatekeeper at the interface between body and diet and is thought to play an important role in the etiology of obesity and associated metabolic disorders. A computational modelling approach was used to improve our understanding of the metabolic responses of epithelial cells to different diets. A constraint based, mouse-specific enterocyte metabolic model (named mmu_ENT717) was constructed to describe the impact of four fully characterized semi-purified diets, that differed in lipid and carbohydrate composition, on uptake, metabolism, as well as secretion of carbohydrates and lipids...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821663/agrp-neurons-can-increase-food-intake-during-conditions-of-appetite-suppression-and-inhibit-anorexigenic-parabrachial-neurons
#13
Rachel A Essner, Alison G Smith, Adam A Jamnik, Anna R Ryba, Zoe D Trutner, Matthew E Carter
To maintain energy homeostasis, orexigenic (appetite-inducing) and anorexigenic (appetite suppressing) brain systems functionally interact to regulate food intake. Within the hypothalamus, neurons that express agouti-related protein (AgRP) sense orexigenic factors and orchestrate an increase in food-seeking behavior. In contrast, calcitonin gene-related peptide (CGRP)-expressing neurons in the parabrachial nucleus (PBN) suppress feeding. PBN CGRP neurons become active in response to anorexigenic hormones released following a meal, including amylin, secreted by the pancreas, and cholecystokinin (CCK), secreted by the small intestine...
August 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821636/twenty-four-hour-rhythmicity-of-circulating-metabolites-effect-of-body-mass-and-type-2-diabetes
#14
Cheryl M Isherwood, Daan R Van der Veen, Jonathan D Johnston, Debra J Skene
Metabolic profiling of individuals with type 2 diabetes mellitus (T2DM) has previously been limited to single-time-point samples, ignoring time-of-day variation. Here, we tested our hypothesis that body mass and T2DM affect daily rhythmicity and concentrations of circulating metabolites across a 24-h day in 3 age-matched, male groups-lean, overweight/obese (OW/OB), and OW/OB with T2DM-in controlled laboratory conditions, which were not confounded by large meals. By using targeted liquid chromatography/mass spectrometry metabolomics, we quantified 130 plasma metabolites every 2 h over 24 h, and we show that average metabolite concentrations were significantly altered by increased body mass (90 of 130) and T2DM (56 of 130)...
August 18, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28821567/chronic-spinal-cord-changes-in-a-high-fat-diet-fed-male-rat-model-of-thoracic-spinal-contusion
#15
Redin A Spann, William J Lawson, Raymond J Grill, Michael R Garrett, Bernadette E Grayson
Individuals that suffer injury to the spinal cord can result in long-term, debilitating sequelae. Spinal cord injured patients have increased risk for the development of metabolic disease which can further hinder the effectiveness of treatments to rehabilitate the cord and improve quality of life. In the present study, we sought to understand the impact of high-fat diet induced obesity on spinal cord injury (SCI) by examining transcriptome changes in the area of the injury and rostral and caudal to site of damage 12 weeks after injury...
August 18, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28821510/social-and-somatic-determinants-of-underweight-overweight-and-obesity-at-5-years-of-age-a-norwegian-regional-cohort-study
#16
Hilde Mjell Donkor, Jacob Holter Grundt, Pétur Benedikt Júlíusson, Geir Egil Eide, Jørgen Hurum, Robert Bjerknes, Trond Markestad
OBJECTIVE: To identify associations between the weight groups underweight (UW), overweight (OW) and obesity (OB) at 5 years of age and exposures related to pregnancy, anthropometric measures at birth, sociodemographic factors, and family health, anthropometric measures and habits. DESIGN: Regional cohort study. SETTING: Oppland County, Norway. METHODS: Pregnancy data were obtained from a prospective perinatal register for children born in the county, and weight and height were measured by midwives at birth and by public health nurses at 5 years...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821502/overweight-and-obese-children-do-not-consult-their-general-practitioner-more-often-than-normal-weight-children-for-musculoskeletal-complaints-during-a-2-year-follow-up
#17
Janneke van Leeuwen, Marienke van Middelkoop, Winifred D Paulis, Herman J Bueving, Patrick J E Bindels, Bart W Koes
BACKGROUND: Childhood obesity is associated with self-reported musculoskeletal complaints, injuries and fractures. In the current study, we investigated the association between weight status of children and the frequency and type of musculoskeletal consultations at the general practitioner (GP) during a 2-year follow-up. METHODS: Data from a prospective longitudinal cohort study including children aged 2-18 years presenting in general practices in the Netherlands were used...
August 18, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28821495/obesity-type-2-diabetes-and-metformin
#18
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28821476/bma-calls-for-tougher-action-on-food-industry-to-curb-childhood-obesity
#19
Abi Rimmer
No abstract text is available yet for this article.
August 18, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28821446/diet-induced-obesity-alters-memory-consolidation-in-female-rats
#20
P Zanini, B D Arbo, G Niches, D Czarnabay, F Benetti, M F Ribeiro, A L Cecconello
Obesity is a multifactorial disease characterized by the abnormal or excessive fat accumulation, which is caused by an energy imbalance between consumed and expended calories. Obesity leads to an inflammatory response that may result in peripheral and central metabolic changes, including insulin and leptin resistance. Insulin and leptin resistance have been associated with metabolic and cognitive dysfunctions. Obesity and some neurodegenerative diseases that lead to dementia affect mainly women. However, the effects of diet-induced obesity on memory consolidation in female rats are poorly understood...
August 15, 2017: Physiology & Behavior
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