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https://www.readbyqxmd.com/read/28718347/priming-involuntary-autobiographical-memories-in-the-lab
#1
Krystian Barzykowski, Agnieszka Niedźwieńska
Involuntary autobiographical memories (IAMs) are recollections of personal past that frequently and spontaneously occur in daily life. Initial studies by Mace ( 2005 ) showed that deliberately reminiscing about a certain lifetime period (e.g., high school) significantly increased the number of different IAMs from the same period in subsequent days, suggesting that priming may play a significant role in the retrieval of IAMs in everyday life. In the present study, we used a modified experimental paradigm, originally used by Schlagman and Kvavilashvili ( 2008 ), to study IAMs under well-controlled laboratory conditions...
July 18, 2017: Memory
https://www.readbyqxmd.com/read/28712949/role-of-early-second-trimester-uterine-artery-doppler-screening-to-predict-small-for-gestational-age-babies-in-nulliparous-women
#2
Samuel Parry, Anthony Sciscione, David M Haas, William A Grobman, Jay D Iams, Brian M Mercer, Robert M Silver, Hyagriv N Simhan, Ronald J Wapner, Deborah A Wing, Michal A Elovitz, Frank P Schubert, Alan Peaceman, M Sean Esplin, Steve Caritis, Michael P Nageotte, Benjamin A Carper, George R Saade, Uma M Reddy, Corette B Parker
BACKGROUND: Trophoblastic invasion of the uterine spiral arteries substantially increases compliance to accommodate increased blood flow to the placenta. Failure of this process impedes uterine artery blood flow, and this may be detected by uterine artery Doppler flow studies. However, the clinical utility of uterine artery Doppler flow studies in the prediction of adverse pregnancy outcomes in a general population remains largely unknown. OBJECTIVE: To determine the utility of early second trimester uterine artery Doppler studies as a predictor of small for gestational age (SGA) neonates...
July 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28697250/vaginal-fetal-fibronectin-to-predict-spontaneous-preterm-birth-reply
#3
M Sean Esplin, Michal Elovitz, Jay Iams
No abstract text is available yet for this article.
July 11, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28694791/no-clear-differences-between-organic-or-conventional-pig-farms-in-the-genetic-diversity-or-virulence-of-campylobacter-coli-isolates
#4
Martine Denis, Bérengère Nagard, Valérie Rose, Kévin Bourgoin, Mélina Cutimbo, Annaëlle Kerouanton
To evaluate the impact of pig farm management on the genetic diversity and on the virulence of Campylobacter coli, we characterized isolates from 19 organic pig farms (62 isolates) and from 24 conventional pig farms (58 isolates). The 120 C. coli isolates were typed using pulsed field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) and the presence of nine virulence genes was screened using real-time PCR. The capacity of adhesion and invasion of 61 isolates (32 from organic and 29 from conventional farms) were then tested on human intestinal Caco-2 cells...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28691828/virulence-and-antibiotic-resistance-genes-in-campylobacter-spp-in-the-czech-republic
#5
J Bardoň, V Pudová, I Koláčková, R Karpíšková, M Röderová, M Kolář
OBJECTIVE: Thermotolerant species of the genus Campy-lobacter are the important agents causing human foodborne infections throughout the world. The aims of this study were to evaluate the presence of nine putative virulence genes in Campylobacter spp. isolated from patients and from foods (poultry meat, pork liver), to determine the resistance of Campylobacter isolates to eight antibiotic agents and to detect four resistance genes.Matherial and methods: The presence of the virulence genes cdtA, cdtB, cdtC, virB11, ciaB, wlaN, iam, dnaJ and racR was detected by polymerase chain reaction (PCR) in 94 Campylobacter spp...
2017: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/28688767/the-activation-of-b-cells-enhances-dc-sign-expression-and-promotes-susceptibility-of-b-cells-to-hpai-h5n1-infection
#6
Prasit Na-Ek, Jutarat Thewsoongnoen, Maytawan Thanunchai, Suwimon Wiboon-Ut, Noppadol Sa-Ard-Iam, Rangsini Mahanonda, Arunee Thitithanyanont
The interplay between highly pathogenic avian influenza (HPAI) H5N1 virus and immune cells has been extensively studied for years, as host immune components are thought to play significant roles in promoting the systemic spread of the virus and in the induction of cytokine storm. Previous studies suggested that the interaction of B cells and monocytes could promote HPAI H5N1 infection by enhancing avian influenza virus receptor expression. In this study, we further investigate the relationship between the HPAI H5N1 virus, activated B cells, and DC-SIGN expression...
July 5, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28672008/nanofibrous-scaffolds-for-the-guidance-of-stem-cell-derived-neurons-for-auditory-nerve-regeneration
#7
Sandra Hackelberg, Samuel J Tuck, Long He, Arjun Rastogi, Christina White, Liqian Liu, Diane M Prieskorn, Ryan J Miller, Che Chan, Benjamin R Loomis, Joseph M Corey, Josef M Miller, R Keith Duncan
Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for hearing loss occurring independently or in addition to sensory hair cell damage. Unfortunately, mammalian SGNs lack the potential for autonomous regeneration. Stem cell based therapy is a promising approach for auditory nerve regeneration, but proper integration of exogenous cells into the auditory circuit remains a fundamental challenge. Here, we present novel nanofibrous scaffolds designed to guide the integration of human stem cell-derived neurons in the internal auditory meatus (IAM), the foramen allowing passage of the spiral ganglion to the auditory brainstem...
2017: PloS One
https://www.readbyqxmd.com/read/28644732/lipophilicity-and-biomimetic-properties-to-support-drug-discovery
#8
Fotios Tsopelas, Constantinos Giaginis, Anna Tsantili-Kakoulidou
Lipophilicity, expressed as the octanol-water partition coefficient, constitutes the most important property in drug action, influencing both pharmacokinetic and pharmacodynamics processes as well as drug toxicity. On the other hand, biomimetic properties defined as the retention outcome on HPLC columns containing a biological relevant agent, provide a considerable advance for rapid experimental - based estimation of ADME properties in early drug discovery stages. Areas covered: This review highlights the paramount importance of lipophilicity in almost all aspects of drug action and safety...
June 28, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28599896/objectively-measured-short-sleep-duration-and-later-sleep-midpoint-in-pregnancy-are-associated-with-a-higher-risk-of-gestational-diabetes
#9
Francesca L Facco, William A Grobman, Kathryn J Reid, Corette B Parker, Shannon M Hunter, Robert M Silver, Robert C Basner, George R Saade, Grace W Pien, Shalini Manchanda, Judette M Louis, Chia-Ling Nhan-Chang, Judith H Chung, Deborah A Wing, Hyagriv N Simhan, David M Haas, Jay Iams, Samuel Parry, Phyllis C Zee
BACKGROUND: Experimental and epidemiologic data suggest that among nonpregnant adults, sleep duration may be an important risk factor for chronic disease. Although pregnant women commonly report poor sleep, few studies objectively evaluated the quality of sleep in pregnancy or explored the relationship between sleep disturbances and maternal and perinatal outcomes. OBJECTIVE: Our objective was to examine the relationship between objectively assessed sleep duration, timing, and continuity (measured via wrist actigraphy) and maternal cardiovascular and metabolic morbidity specific to pregnancy...
June 7, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28596636/no-gold-standard-evaluation-of-image-acquisition-methods-using-patient-data
#10
Abhinav K Jha, Eric Frey
Several new and improved modalities, scanners, and protocols, together referred to as image-acquisition methods (IAMs), are being developed to provide reliable quantitative imaging. Objective evaluation of these IAMs on the clinically relevant quantitative tasks is highly desirable. Such evaluation is most reliable and clinically decisive when performed with patient data, but that requires the availability of a gold standard, which is often rare. While no-gold-standard (NGS) techniques have been developed to clinically evaluate quantitative imaging methods, these techniques require that each of the patients be scanned using all the IAMs, which is expensive, time consuming, and could lead to increased radiation dose...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28579562/crystal-structure-and-electrostatic-properties-of-prednisolone-acetate-studied-using-a-transferred-multipolar-atom-model
#11
Ammara Shahid, Sajida Noureen, Muhammad Iqbal Choudhary, Sammer Yousuf, Maqsood Ahmed
Prednisolone acetate {systematic name: 2-[(8S,9S,10R,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl acetate}, is an ophthalmic drug that belongs to the class of corticosteroids. Its crystal structure was refined using the classical independent atom model (IAM) and a transferred multipolar atom model using the ELMAM2 database. The results of both refinements have been compared. The ELMAM2 refinement was found to be superior in terms of the refinement statistics...
June 1, 2017: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/28522317/the-association-among-cytochrome-p450-3a-progesterone-receptor-polymorphisms-plasma-17-alpha-hydroxyprogesterone-caproate-concentrations-and-spontaneous-preterm-birth
#12
Martha L Bustos, Steve N Caritis, Kathleen A Jablonski, Uma M Reddy, Yoram Sorokin, Tracy Manuck, Michael W Varner, Ronald J Wapner, Jay D Iams, Marshall W Carpenter, Alan M Peaceman, Brian M Mercer, Anthony Sciscione, Dwight J Rouse, Susan M Ramin
BACKGROUND: Infants born <37 weeks' gestation are of public health concern since complications associated with preterm birth are the leading cause of mortality in children <5 years of age and a major cause of morbidity and lifelong disability. The administration of 17-alpha hydroxyprogesterone caproate reduces preterm birth by 33% in women with history of spontaneous preterm birth. We demonstrated previously that plasma concentrations of 17-alpha hydroxyprogesterone caproate vary widely among pregnant women and that women with 17-alpha hydroxyprogesterone caproate plasma concentrations in the lowest quartile had spontaneous preterm birth rates of 40% vs rates of 25% in those women with higher concentrations...
May 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28515389/ca-2-in-hybridization-solutions-for-fluorescence-in-situ-hybridization-facilitates-the-detection-of-enterobacteriaceae
#13
Shin Haruta, Takao Iino, Moriya Ohkuma, Ken-Ichiro Suzuki, Yasuo Igarashi
Fluorescence in situ hybridization (FISH) has been employed to identify microorganisms at the single cell level under a microscope. Extensive efforts have been made to improve and extend the FISH technique; however, the development of a widely applicable protocol is a continuing challenge. The present study evaluated the effects of divalent cations in the hybridization solution on the FISH-based detection of various species of bacteria and archaea with rRNA-targeted probes. A flow cytometric analysis after FISH with a standard hybridization buffer detected positive signals from less than 30% of Escherichia coli IAM 1264 cells...
June 24, 2017: Microbes and Environments
https://www.readbyqxmd.com/read/28505683/tranexamic-acid-effectively-reduces-blood-loss-and-transfusion-rates-during-simultaneous-bilateral-total-knee-arthroplasty
#14
Hernan A Prieto, Heather K Vincent, Justin T Deen, Dane A Iams, Hari K Parvataneni
No abstract text is available yet for this article.
May 15, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28494993/robust-activation-detection-methods-for-real-time-and-offline-fmri-analysis
#15
Kaya Oguz, Muhammed G Cinsdikici, Ali Saffet Gonul
We propose two contributions with novel approaches to fMRI activation analysis. The first is to apply confidence intervals to locate activations in real-time, and second is a new metric based on robust regression of fMRI signals. These contributions are implemented in our four proposed methods; Instantaneous Activation Method (IAM), Instantaneous Activation Method with Past Blocks (IAMP) for real-time analysis, Task Robust Regression Distance Method (TRRD) for the new metric with robust regression and Instantaneous Robust Regression Distance Method (IRRD) for both contributions...
June 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28489217/intra-aortic-balloon-pump-in-cardiogenic-shock-state-of-the-art
#16
Petronio Generoso Thomaz, Leonel Adelino Moura, Giovana Muramoto, Renato Samy Assad
The clinical definition of cardiogenic shock is that of a low cardiac output and evidence of tissue hypoxia in the presence of adequate blood volume. Cardiogenic shock is the main cause of death related to acute myocardial infarction (AMI), with a mortality rate of 45-70% in the absence of aggressive and highly specialized technical care. The intra-aortic balloon pump (IABP) is one of the most widely used mechanical assisting devices. During the last two decades, about 42% of patients with AMI who evolved with cardiogenic shock received mechanical circulatory assistance with IABP...
January 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28468424/manipulating-surface-plasmon-polaritons-with-infinitely-anisotropic-metamaterials
#17
Zheping Shao, Yihao Yang, Zuojia Wang, Muhiddeen Yahaya, Bin Zheng, Shahram Dehdashti, Huaping Wang, Hongsheng Chen
Guiding surface states through disorders recently has attracted attention of scientists from diverse backgrounds. In this work, we report a robust method to guide surface plasmon polaritons (SPPs) through arbitrary distorted metal surfaces (a kind of disorder), including slopes, bumps, and sharp corners. Almost total transmissions over a broad frequency range can be achieved by use of infinitely anisotropic metamaterials (IAMs). The SPPs are coupled into and out of the bulk modes in the IAMs, where the bulk modes are routed by altering the principle axis of the IAMs...
May 1, 2017: Optics Express
https://www.readbyqxmd.com/read/28451989/tissue-engineered-human-amniotic-membrane-application-in-mouse-ovarian-follicular-culture
#18
M Motamed, Z Sadr, M R Valojerdi, A Moini, S Oryan, M Totonchi, B Ebrahimi, S Maroufizadeh, E Taghiabadi, R Fathi
Since folliculogenesis requires a powerful cell-matrix interaction, natural scaffolds seem to be needed for follicular culture. Human amniotic membrane (HAM) offers promise as a support of in vitro ovarian follicular culture. HAM was decellularized with trypsin and EDTA. DNA and histology assays were performed to determine the elimination rate of genomic components. Cyto-biocompatibility of decellular AM (DAM) was verified by the cell viability (MTT) test. The small parts of intact amniotic membrane (IAM) and DAM were coated on the bottom of 96-well and each well was filled with 150 µL of base medium...
April 27, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28448792/imagining-possible-selves-across-time-characteristics-of-self-images-and-episodic-thoughts
#19
J Hamilton, S N Cole
Thinking about our possible selves can entail thinking about self-related imagined future events. When remembering and imagining, individuals can use both 1st person (field) and 3rd person (observer) perspectives. There is currently a paucity of research examining the visual perspectives of episodic future thoughts that represent possible selves. We hypothesised that temporally distant self-images would elicit more observer perspectives in episodic thoughts than temporally near self-images and current self-images...
April 24, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28435859/the-frequency-and-extent-of-sub-ice-phytoplankton-blooms-in-the-arctic-ocean
#20
Christopher Horvat, David Rees Jones, Sarah Iams, David Schroeder, Daniela Flocco, Daniel Feltham
In July 2011, the observation of a massive phytoplankton bloom underneath a sea ice-covered region of the Chukchi Sea shifted the scientific consensus that regions of the Arctic Ocean covered by sea ice were inhospitable to photosynthetic life. Although the impact of widespread phytoplankton blooms under sea ice on Arctic Ocean ecology and carbon fixation is potentially marked, the prevalence of these events in the modern Arctic and in the recent past is, to date, unknown. We investigate the timing, frequency, and evolution of these events over the past 30 years...
March 2017: Science Advances
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