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https://www.readbyqxmd.com/read/28099589/which-coronary-lesions-are-more-prone-to-cause-acute-myocardial-infarction
#1
Taner Sen, Mehmet Ali Astarcioglu, Osman Beton, Lale Dinc Asarcikli, Celal Kilit
Background: According to common belief, most myocardial infarctions (MIs) are due to the rupture of nonsevere, vulnerable plaques with < 70% obstruction. Data from recent trials challenge this belief, suggesting that the risk of coronary occlusion is, in fact, much higher after severe stenosis. The aim of this study was to investigate whether or not acute ST-elevation MIs result from high-grade stenoses by evaluating the presence of coronary collateral circulation (CCC). Methods: We retrospectively included 207 consecutive patients who had undergone primary percutaneous coronary intervention for acute ST-elevation MI...
January 16, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28079774/a-statewide-progestogen-promotion-program-in-ohio
#2
Jay D Iams, Mary S Applegate, Michael P Marcotte, Martha Rome, Michael A Krew, Jennifer L Bailit, Heather C Kaplan, Jessi Poteet, Melissa Nance, David S McKenna, Hetty C Walker, Jennifer Nobbe, Lakshmi Prasad, Maurizio Macaluso, Carole Lannon
OBJECTIVE: To promote use of progestogen therapy to reduce premature births in Ohio by 10%. METHODS: The Ohio Perinatal Quality Collaborative initiated a quality improvement project in 2014 working with clinics at 20 large maternity hospitals, Ohio Medicaid, Medicaid insurers, and service agencies to use quality improvement methods to identify eligible women and remove treatment barriers. The number of women eligible for prophylaxis, the percent prescribed a progestogen before 20 and 24 weeks of gestation, and barriers encountered were reported monthly...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28076446/downscaling-global-emissions-and-its-implications-derived-from-climate-model-experiments
#3
Shinichiro Fujimori, Manabu Abe, Tsuguki Kinoshita, Tomoko Hasegawa, Hiroaki Kawase, Kazuhide Kushida, Toshihiko Masui, Kazutaka Oka, Hideo Shiogama, Kiyoshi Takahashi, Hiroaki Tatebe, Minoru Yoshikawa
In climate change research, future scenarios of greenhouse gas and air pollutant emissions generated by integrated assessment models (IAMs) are used in climate models (CMs) and earth system models to analyze future interactions and feedback between human activities and climate. However, the spatial resolutions of IAMs and CMs differ. IAMs usually disaggregate the world into 10-30 aggregated regions, whereas CMs require a grid-based spatial resolution. Therefore, downscaling emissions data from IAMs into a finer scale is necessary to input the emissions into CMs...
2017: PloS One
https://www.readbyqxmd.com/read/27988185/global-land-use-allocation-model-linked-to-an-integrated-assessment-model
#4
Tomoko Hasegawa, Shinichiro Fujimori, Akihiko Ito, Kiyoshi Takahashi, Toshihiko Masui
We developed a global land-use allocation model that can be linked to integrated assessment models (IAMs) with a coarser spatial resolution. Using the model, we performed a downscaling of the IAMs' regional aggregated land-use projections to obtain a spatial land-use distribution, which could subsequently be used by Earth system models for global environmental assessments of ecosystem services, food security, and climate policies. Here we describe the land-use allocation model, discuss the verification of the downscaling technique, and explain the influences of the downscaling on estimates of land-use carbon emissions...
December 14, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27974157/development-of-double-chain-phosphatidylcholine-functionalized-polymeric-monoliths-for-immobilized-artificial-membrane-chromatography
#5
Qiqin Wang, Kun Peng, Weijia Chen, Zhen Cao, Peijie Zhu, Yumei Zhao, Yuqiang Wang, Haibo Zhou, Zhengjin Jiang
This study described a simple synthetic methodology for preparing biomembrane mimicking monolithic column. The suggested approach not only simplifies the preparation procedure but also improves the stability of double chain phosphatidylcholine (PC) functionalized monolithic column. The physicochemical properties of the optimized monolithic column were characterized by scanning electron microscopy, energy-dispersive X-ray spectrometry, and nano-LC. Satisfactory column permeability, efficiency, stability and reproducibility were obtained on this double chain PC functionalized monolithic column...
January 6, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27969535/ps01-68-heterogeneous-clinical-syndromes-existing-within-patients-with-stage-iv-kras-mutant-non-small-cell-lung-cancer-topic-medical-oncology
#6
Wade T Iams, Hui Yu, Yu Shyr, Tejas Patil, Leora Horn, Caroline McCoach, Karen Kelly, Robert Doebele, David R Camidge
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27923442/bullying-and-defending-behavior-the-role-of-explicit-and-implicit-moral-cognition
#7
Tiziana Pozzoli, Gianluca Gini, Robert Thornberg
Research on bullying has highlighted the role of morality in explaining the different behavior of students during bullying episodes. However, the research has been limited to the analysis of explicit measures of moral characteristics and moral reasoning, whereas implicit measures have yet to be fully considered. To overcome this limitation, this study investigated the association between bullying and defending, on one hand, and both explicit (moral disengagement, self-importance of moral values) and implicit (immediate affect toward moral stimuli [IAMS]) moral components, on the other hand...
December 2016: Journal of School Psychology
https://www.readbyqxmd.com/read/27919703/prediction-and-mechanism-elucidation-of-analyte-retention-on-phospholipid-stationary-phases-iam-hplc-by-in-silico-calculated-physico-chemical-descriptors
#8
Giacomo Russo, Lucia Grumetto, Francesco Barbato, Giulio Vistoli, Alessandro Pedretti
The present study proposes a method for an in silico calculation of phospholipophilicity. Phospholipophilicity is intended as the measure of analyte affinity for phospholipids; it is currently assessed by HPLC measures of analyte retention on phosphatidylcholine-like stationary phases (IAM - Immobilized Artificial Membrane) resulting in log kW(IAM) values. Due to the amphipathic and electrically charged nature of phospholipids, retention on these stationary phases results from complex mechanisms, being affected not only by lipophilicity (as measured by n-octanol/aqueous phase partition coefficients, log P) but also by the occurrence of polar and/or electrostatic intermolecular interaction forces...
December 3, 2016: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27917307/clinical-and-cost-impact-analysis-of-a-novel-prognostic-test-for-early-detection-of-preterm-birth
#9
Aaron B Caughey, John A F Zupancic, James M Greenberg, Susan S Garfield, Stephen F Thung, Jay D Iams
Objective The objective of this study was to evaluate the potential impact to the U.S. health care system by adopting a novel test that identifies women at risk for spontaneous preterm birth. Methods A decision-analytic model was developed to assess clinical and cost outcomes over a 1-year period. The use of a prognostic test to predict spontaneous preterm birth in a hypothetical population of women reflective of the U.S. population (predictive arm) was compared with the current baseline rate of spontaneous preterm birth and associated infant morbidity and mortality (baseline care arm)...
October 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27916390/chromatographic-behavior-of-selected-antibiotic-drugs-supported-by-quantitative-structure-retention-relationships
#10
Malgorzata Szultka-Mlynska, Boguslaw Buszewski
As antibiotic drugs have a wide variety of applications, there is a growing demand for their selective determination, a task for which chromatographic methods seem to be appropriate. With this end in view, chromatographic measurements were performed with the use of six different HPLC columns (ACE 5C18, IAM.PC.DD.2, octadecyl, phenyl, alkylamide and cholesteryl-alkylamide) to determine the logkw of selected antibiotic drugs (amoxicillin, cefatoxime, ciprofloxacin, fluconazole, gentamicin, clindamycin, linezolid and metronidazole)...
December 23, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27910733/a-comparative-morphologic-and-morphometric-study-about-geniculate-ganglion-development-in-man-and-in-rat
#11
Ana Sánchez-Del-Rey, José Maria Sánchez-Fernández, Arantza Ibargutxi, Agustin Martinez-Ibargüen, Francisco Santaolalla
CONCLUSIONS: Human-rat geniculate ganglion (GG) have multiple origins: (1) An initial proximity (20 μm) to the endocranial foramen of the IAM, suggests neural crest induction; and (2) The influence of epibranchial placodes: the tensor tympani muscle (TTM) and the otic apical coil. OBJECTIVES: This study was undertaken to determine the comparative development of human-rat GG. MATERIALS AND METHODS: A light microscopic study of the GG in human material obtained from spontaneous abortions at 9, 13, 14, 17, 18, and 30 weeks, and one neonate was done...
December 2, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27897385/reconstruction-of-biological-pathways-and-metabolic-networks-from-in-silico-labeled-metabolites
#12
Noushin Hadadi, Jasmin Hafner, Keng Cher Soh, Vassily Hatzimanikatis
Reaction atom mappings track the positional changes of all of the atoms between the substrates and the products as they undergo the biochemical transformation. However, information on atom transitions in the context of metabolic pathways is not widely available in the literature. The understanding of metabolic pathways at the atomic level is of great importance as it can deconvolute the overlapping catabolic/anabolic pathways resulting in the observed metabolic phenotype. The automated identification of atom transitions within a metabolic network is a very challenging task since the degree of complexity of metabolic networks dramatically increases when we transit from metabolite-level studies to atom-level studies...
November 29, 2016: Biotechnology Journal
https://www.readbyqxmd.com/read/27896793/self-assembled-formation-of-well-aligned-cu-te-nano-rods-on-heavily-cu-doped-znte-thin-films
#13
Jing Liang, Man Kit Cheng, Ying Hoi Lai, Guanglu Wei, Sean Derman Yang, Gan Wang, Sut Kam Ho, Kam Weng Tam, Iam Keong Sou
Cu doping of ZnTe, which is an important semiconductor for various optoelectronic applications, has been successfully achieved previously by several techniques. However, besides its electrical transport characteristics, other physical and chemical properties of heavily Cu-doped ZnTe have not been reported. We found an interesting self-assembled formation of crystalline well-aligned Cu-Te nano-rods near the surface of heavily Cu-doped ZnTe thin films grown via the molecular beam epitaxy technique. A phenomenological growth model is presented based on the observed crystallographic morphology and measured chemical composition of the nano-rods using various imaging and chemical analysis techniques...
December 2016: Nanoscale Research Letters
https://www.readbyqxmd.com/read/27888998/jay-d-iams-md-ajog-editor
#14
EDITORIAL
Roberto Romero, Ingrid Nygaard
No abstract text is available yet for this article.
December 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27849863/221-choosing-wisely-an-apn-led-initiative-to-reduce-unnecessary-chest-x-rays-in-the-cardiovascular-icu
#15
Lauren Oliver, Jayme Gibson, April Kapu, Ruth Kleinpell, Wade Iams, Pierce Trumbo
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27790738/comparative-molecular-field-analysis-of-chromatographic-hydrophobicity-indices-for-some-coumarin-analogs
#16
Mohammad Hossein Fatemi, Zahra Shakoori, Kobra Samghani
The chromatographic hydrophobicity index (CHI) is an HPLC-based parameter that provides reliable guidance in optimization of pharmacological efficiency and adsorption, distribution, metabolism and exertion (ADME) profile of drug candidates. In the present work, classical and three-dimensional quantitative structure-property relationship (QSPR) models were developed for prediction of CHI values of some 4-hydroxycoumarin analogs on immobilized artificial membrane column. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) as 3D-QSPR methods were performed to gain insight into the key structural factors affecting on the chromatographic hydrophobicity of interested chemicals...
October 27, 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/27782197/high-efficiency-holographic-bragg-grating-with-optically-prolonged-memory
#17
Iam Choon Khoo, Chun-Wei Chen, Tsung-Jui Ho
In this paper, we show that photosensitive azo-dye doped Blue-phase liquid crystals (BPLC) formed by natural molecular self-assembly are capable of high diffraction efficiency holographic recording with memory that can be prolonged from few seconds to several minutes by uniform illumination with the reference beam. Operating in the Bragg regime, we have observed 50 times improvement in the grating diffraction efficiency and shorter recording time compared to previous investigations. The enabling mechanism is BPLC's lattice distortion and index modulation caused by the action of light on the azo-dopant; upon photo-excitation, the azo-molecules undergo transformation from the oblong-shaped Trans-state to the bent-shaped Cis-state, imparting disorder and also cause the surrounding BPLC molecules to undergo coupled flow &reorientation leading to lattice distortion and index modulation...
October 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27767177/optimal-bioenergy-power-generation-for-climate-change-mitigation-with-or-without-carbon-sequestration
#18
Dominic Woolf, Johannes Lehmann, David R Lee
Restricting global warming below 2 °C to avoid catastrophic climate change will require atmospheric carbon dioxide removal (CDR). Current integrated assessment models (IAMs) and Intergovernmental Panel on Climate Change scenarios assume that CDR within the energy sector would be delivered using bioenergy with carbon capture and storage (BECCS). Although bioenergy-biochar systems (BEBCS) can also deliver CDR, they are not included in any IPCC scenario. Here we show that despite BECCS offering twice the carbon sequestration and bioenergy per unit biomass, BEBCS may allow earlier deployment of CDR at lower carbon prices when long-term improvements in soil fertility offset biochar production costs...
October 21, 2016: Nature Communications
https://www.readbyqxmd.com/read/27766877/reactions-of-2-propanol-radical-with-halogenated-organics-in-aqueous-solution-theoretical-evidence-for-proton-coupled-electron-transfer-and-competing-mechanisms
#19
Ivan Ljubić, Aleksandar Sabljić, Marija Bonifačić
The reactions of α-hydroxyalkyl radicals in aqueous medium are of interest because they exhibit a rich variety of fundamentally important competing mechanisms, such as proton-coupled electron transfer (PCET), hydrogen atom transfer, free radical substitutions, abstractions and additions, etc. We present a theoretical study of the mechanism and kinetics of the aqueous reactions of α-hydroxyisopropyl (2-propanol) radical with four halogenated organic substrates: iodoacetate (IAc), iodoacetamide (IAm), 5-bromouracil (5-BrU), and carbon tetrachloride (CCl4)...
November 17, 2016: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/27763332/innovation-results-of-iam-planning-in-urban-water-services
#20
M A Cardoso, A Poças, M S Silva, R Ribeiro, M C Almeida, R S Brito, S T Coelho, H Alegre
The requirement to provide urban water services continuously while infrastructures are ageing, imposes the need for increasingly sustainable infrastructure asset management (IAM). To achieve and maintain adequate levels of service, the AWARE-P IAM methodology has been applied in collaborative projects launched by the National Civil Engineering Laboratory, in partnership with IST (Technical University of Lisbon), Addition (software company) and several water utilities. The objective of these projects is to support urban water utilities in the development, implementation and maintenance of IAM plans...
October 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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