Honge Gui, Pan Xiao, Bintao Xu, Xiaole Zhao, Hongyu Wang, Li Tao, Xiaoyu Zhang, Qin Li, Xueyan Zhang, Huiyue Chen, Hansheng Wang, Fajin Lv, Tianyou Luo, Oumei Cheng, Jin Luo, Yun Man, Zheng Xiao, Weidong Fang
BACKGROUND: Essential tremor (ET) and dystonic tremor (DT) are the two most common tremor disorders, and misdiagnoses are very common due to similar tremor symptoms. In this study, we explore the structural network mechanisms of ET and DT using brain grey matter (GM) morphological networks and combine those with machine learning models. METHODS: 3D-T1 structural images of 75 ET patients, 71 DT patients, and 79 healthy controls (HCs) were acquired. We used voxel-based morphometry to obtain GM images and constructed GM morphological networks based on the Kullback-Leibler divergence-based similarity (KLS) method...
April 28, 2024: Parkinsonism & related Disorders