keyword
https://read.qxmd.com/read/38050394/expedited-awake-tracheal-intubation-using-ropivacaine-topicalisation-for-the-evacuation-of-a-postoperative-neck-haematoma-in-the-presence-of-lignocaine-allergy
#21
JOURNAL ARTICLE
Walston Martis, Rani Chahal
Progressive airway compromise from a neck haematoma is a feared complication of head and neck surgery that can rapidly lead to death if not urgently intervened upon. We report a case of a patient developing a progressively expanding neck haematoma on the first postoperative night after parotidectomy and neck dissection for malignancy. Although he did not have respiratory compromise or stridor, ultrasound examination of his airway revealed marked tracheal deviation, and flexible nasoendoscopy showed significant supraglottic swelling...
December 1, 2023: BMJ Case Reports
https://read.qxmd.com/read/38025547/comparative-evaluation-of-lignocaine-nebulization-with-and-without-dexmedetomidine-for-flexible-videoendoscopic-guided-awake-nasal-intubation-for-general-anaesthesia
#22
JOURNAL ARTICLE
Jyoti Gaikawad, Santosh Choudhary, Sandeep Sharma, Khemraj Meena, Devendra Verma, Vikram Bedi
BACKGROUND AND AIMS: Awake fibreoptic intubation is considered a safe approach in airway management of a patient with difficult airway. Awake fibreoptic endoscopy needs appropriate anaesthesia of airway to suppress airway reflexes and prevent discomfort. We planned this study to evaluate effect of adding dexmedetomidine to lignocaine nebulization on conditions for awake videoendoscopic intubation. MATERIAL AND METHODS: In this prospective randomized double blind controlled study, ninety six ASA grade I, II patients of either gender, aged 18-65 years, scheduled for elective surgeries under general anaesthesia, were randomly allocated into two groups, Group D and L to receive nebulization with 4% Lignocaine 5 ml + Dexmedetomidine 2 mcg/kg and 4% Lignocaine alone respectively, 20 min before procedure...
2023: Journal of Anaesthesiology, Clinical Pharmacology
https://read.qxmd.com/read/38021496/comparative-evaluation-of-electronic-acupuncture-pen-and-2-lignocaine-gel-as-an-intraoral-topical-anesthetic-agent-in-children
#23
JOURNAL ARTICLE
Pranjali V Deulkar, Nilesh V Rathi, Nilima Thosar, Sphurti P Bane, Meghana A Deshpande
Background The most exasperating aspect for pediatric patients in a dental setup is the fear and anxiety caused by injections, called "blenophobia". There are numerous local anesthetic agents available to reduce the needle prick pain. Taking into consideration the paradigm shift, there is always a possibility for alternate treatment options. This study aimed to evaluate and compare the effectiveness of transcutaneous electrical nerve stimulation (TENS) application through an electronic acupuncture pen (Meridian Energy Acupuncture Pen W-912 GENERIC) and 2% lignocaine gel as an intraoral topical anesthetic agent in children...
October 2023: Curēus
https://read.qxmd.com/read/37942998/topical-anaesthesia-and-decongestion-in-rhinology
#24
JOURNAL ARTICLE
S J M Hale, R Kim, R G Douglas
Topical anaesthesia and decongestion of the sinonasal mucosa are used commonly in rhinology practice to facilitate nasal endoscopy, as well as debridement and biopsies. Topical agents used for sinonasal anaesthesia include lignocaine, tetracaine and cocaine. Unlike lignocaine and tetracaine, cocaine also has a decongestant effect. Phenylephrine, oxymetazoline, xylometazoline or adrenaline are usually added to lignocaine and tetracaine to provide decongestion. Several studies have been performed seeking to identify the optimal nasal preparation for nasal endoscopy in the clinic setting...
November 9, 2023: Rhinology
https://read.qxmd.com/read/37935241/wide-awake-local-anesthesia-and-no-tourniquet-walant-in-upper-limb-fractures
#25
JOURNAL ARTICLE
N Bansal, P Tiwari, P Dev
Wide-awake local anesthesia and no tourniquet (WALANT), first used for hand surgery, has been sparingly described for use in fracture fixation of the upper limb. We present our experience using this technique. 26 patients with upper limb fractures (3 distal radius, 6 radial shaft, 11 ulnar shaft, and 6 olecranon fractures) were operated on using WALANT by three orthopedic surgeons. We used 35-40ml of 2% Lignocaine with 1:80000 Adrenaline(7mg/kg) diluted with normal saline. Numeric Pain Rating (NPR) scoring was done during injection and per-operatively, and the Likert scale was used for the surgeon's satisfaction...
September 2023: Acta Orthopaedica Belgica
https://read.qxmd.com/read/37877882/inferior-alveolar-plus-buccal-nerve-block-decreases-postoperative-pain-scores-at-buccal-mucosal-graft-harvest-site-a-retrospective-analysis
#26
JOURNAL ARTICLE
Vivek Tarigopula, Swarnendu Mandal, Gorrepati Rohith, Abhay S Gaur, Manoj K Das
OBJECTIVE: Postoperative pain at buccal mucosal graft (BMG) harvest site hinders the resumption of food intake. We aim to study the effect of inferior-alveolar nerve block plus buccal nerve block (IANB+BNB) on pain scores. METHODS: This was a retrospective case-control study performed in a single center from July 2021 to July 2022 (ethics committee approval: T/IM-NF/Urology/23/27). We performed IANB+BNB with a mixture of 5 mL each of 1% lignocaine and 0.25% bupivacaine and 4 mg dexamethasone, in addition to local infiltration of 2% lignocaine and (1:100000) epinephrine combination before harvesting BMG...
September 2023: Urol Res Pract
https://read.qxmd.com/read/37868394/autologous-whole-blood-versus-corticosteroid-local-injection-in-treatment-of-plantar-fasciitis-a-randomized-single-blind-placebo-controlled-study
#27
JOURNAL ARTICLE
Nikhil Digra, Anurag Beri, Shashank Sharma, Ramkrishna Verma
BACKGROUND: Autologous whole-blood intralesional injection has attracted interest as a possible means of treatment for chronic plantar fasciitis. We contrasted its effectiveness with that of corticosteroids, which have a longer history of success in treating tendinopathies such as plantar fasciitis. In order to monitor the disease's progress naturally, we also compared them with a placebo. METHODS: Sixty clinically diagnosed patients were taken up for intralesional injection of autologous whole blood (AWB), corticosteroid, and normal saline as placebo mixed with 2 mL of lignocaine after dividing them into three groups...
September 2023: Curēus
https://read.qxmd.com/read/37829774/quantitative-assessment-of-ultrasound-guided-sciatic-nerve-block-a-comparison-of-a-single-point-versus-two-point-injection-technique-a-randomised-controlled-double-blinded-trial
#28
JOURNAL ARTICLE
Kusha Nag, M Ravishankar, S Parthasarathy, Tina M Thomas
BACKGROUND AND AIMS: Sciatic nerve block at the popliteal level for lower limb procedures provides unpredictable success rates even with ultrasonographic (USG) guidance. This study aimed to compare USG-guided single-point versus two-point injection techniques . METHODS: Sixty patients posted for foot surgeries under USG-guided sciatic nerve block were randomised into Group Single Point, receiving a single injection of 20 mL of 1.5% lignocaine with adrenaline just proximal to the sciatic nerve bifurcation, and Group Double Point, receiving two injections of 10 mL of 1...
September 2023: Indian Journal of Anaesthesia
https://read.qxmd.com/read/37802488/serum-lidocaine-lignocaine-concentrations-during-prolonged-perioperative-infusion-in-patients-undergoing-breast-cancer-surgery-a-secondary-analysis-of-a-randomised-controlled-trial
#29
RANDOMIZED CONTROLLED TRIAL
Andrew J Toner, Martin A Bailey, Stephan A Schug, Michael Phillips, Jacobus Pj Ungerer, Andrew A Somogyi, Tomas B Corcoran
Perioperative lidocaine (lignocaine) infusions are being employed with increasing frequency. The determinants of systemic lidocaine concentrations during prolonged administration are unclear. In the Long-term Outcomes after Lidocaine Infusions for PostOperative Pain (LOLIPOP) pilot trial, the impact of infusion duration and body size metrics on serum lidocaine concentrations was examined with regression models in 48 women undergoing breast cancer surgery. Lidocaine was delivered as an intravenous bolus (1.5 mg/kg) and infusion (2 mg/kg per h) intraoperatively, followed by a 12-h subcutaneous infusion (1...
November 2023: Anaesthesia and Intensive Care
https://read.qxmd.com/read/37760362/use-of-a-local-anaesthetic-antiseptic-formulation-for-the-treatment-of-lambs-experimentally-infected-with-orf-virus
#30
JOURNAL ARTICLE
Delia Lacasta, Marina Ríos, Marta Ruiz de Arcaute, Aurora Ortín, Juan José Ramos, Sergio Villanueva-Saz, María Teresa Tejedor, Héctor Ruiz, Marta Borobia, Ramsés Reina, Alex Gómez, Teresa Navarro, Peter Andrew Windsor
Contagious ecthyma is a highly transmissible eruptive viral disease of the skin and mucosa of sheep and goats distributed worldwide. The treatment of orf lesions is usually based on the use of antiseptics and antibiotics for the management of presumptive secondary infections, increasing risks of antimicrobial resistance. The wound dressing formulation Tri-Solfen® (TS) containing two local anaesthetics (lignocaine and bupivacaine), adrenaline and an antiseptic (cetrimide) in a gel formulation has been demonstrated to reduce suffering and enhance recovery in cattle and buffalo with oral and skin lesions due to foot-and-mouth disease virus infection and reduced the orf viral load in lambs...
September 19, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/37736776/correction-to-a-comparison-of-two-techniques-of-postoperative-analgesia-lignocaine-fentanyl-intravenous-infusion-and-ropivacaine-fentanyl-epidural-infusion-in-patients-undergoing-cytoreductive-cancer-surgery-crs-and-hyperthermic-intraperitoneal-chemotherapy
#31
Kiran Mahendru, Rakesh Garg, Sachidanand Jee Bharati, Vinod Kumar, Nishkarsh Gupta, Seema Mishra, Sushma Bhatnagar, Mukurdipi Ray, Suryanarayana Deo
No abstract text is available yet for this article.
September 22, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/37719558/comparison-of-animation-distraction-versus-local-anesthetic-application-for-pain-alleviation-in-children-undergoing-intravenous-cannulation-a-randomized-controlled-trial
#32
JOURNAL ARTICLE
Aparna R Thomas, Deepa T Unnikrishnan, Isac Mathai M
Background Medical procedures induce behavioral discomfort, fear, and worry in children and their families, worsening their agony. Reading, playing video games, and watching television lessen anxiety and discomfort. This study aims to compare the pain reduction in children using animation distraction and two percent lignocaine with the control group undergoing intravenous (IV) cannulation using the Visual Analogue Scale (VAS) at a tertiary care hospital in Kolenchery, Kerala, South India, and to study the clinico-social factors influencing pain reduction in children undergoing IV cannulation...
August 2023: Curēus
https://read.qxmd.com/read/37711519/a-clinical-study-for-removal-of-impacted-mandibular-third-molar-under-local-anaesthesia-with-and-without-ketamine-a-split-mouth-comparative-study
#33
JOURNAL ARTICLE
Subham Dutta, R Mahesh Kumar, K R Ashok Kumar, T R Marimallappa, Supriyo Pal, Keerthana Rao
INTRODUCTION: Disimpaction is one of the most common operations done by oral and maxillofacial surgeons around the world. Ketamine is a well-known general anaesthetic and short-acting intraoperative analgesic. The aim of this study was to measure the efficacy of anaesthesia using combined treatment with local anaesthetic plus a subanaesthetic dose of ketamine and local anaesthetic alone in bilaterally impacted mandibular third molar surgery. METHODS AND MATERIALS: A total of 24 patients who consented were taken up for a split-mouth study...
2023: Annals of Maxillofacial Surgery
https://read.qxmd.com/read/37693035/efficacy-of-intravenous-dexmedetomidine-lignocaine-infusion-compared-to-morphine-for-intraoperative-haemodynamic-stability-in-modified-radical-mastectomy-a-randomised-controlled-trial
#34
JOURNAL ARTICLE
Annu Jose, Suvarna Kaniyil, Rashmi Ravindran
BACKGROUND AND AIMS: In recent times, non-opioid analgesic-based anaesthesia has been gaining popularity as it can achieve the goals of hypnosis, amnesia, and haemodynamic stability while avoiding opioid side effects. Our study compares the efficacy of opioid-free anaesthesia and opioid-based general anaesthesia regarding intraoperative haemodynamic stability, anaesthetic requirements, awareness, and recovery profile. METHODS: After receiving ethical approval and registering the trial, we conducted this randomised, single-blinded study on American Society of Anesthesiologists (ASA) physical status I and II patients who were aged 18-65 and were scheduled for modified radical mastectomy under general anaesthesia...
August 2023: Indian Journal of Anaesthesia
https://read.qxmd.com/read/37692744/etomidate-versus-propofol-for-monitored-anesthesia-care-during-endoscopic-retrograde-cholangiopancreatography-a-prospective-randomized-controlled-trial
#35
JOURNAL ARTICLE
Udit Dhingra, Nitin Mantri, Soveena Pani, Deepak K Tempe, Mahesh Arora
Background and objectives Propofol-based sedation is one of the most commonly used methods for endoscopic retrograde cholangiopancreatography (ERCP). The commonest complications during ERCP are in the form of adverse cardiopulmonary events as a result of sedation. Etomidate has a more stable cardiovascular and respiratory profile than propofol and has been used for sedation in simple gastrointestinal endoscopy but has not been studied for procedural sedation in ERCP. The objective of the present study was to compare the safety and feasibility of etomidate and propofol for sedation during ERCP procedures...
August 2023: Curēus
https://read.qxmd.com/read/37615724/a-comparison-of-two-techniques-of-postoperative-analgesia-lignocaine-fentanyl-intravenous-infusion-and-ropivacaine-fentanyl-epidural-infusion-in-patients-undergoing-cytoreductive-cancer-surgery-crs-and-hyperthermic-intraperitoneal-chemotherapy-hipec-prospective
#36
RANDOMIZED CONTROLLED TRIAL
Kiran Mahendru, Rakesh Garg, Sachidanand Jee Bharati, Vinod Kumar, Nishkarsh Gupta, Seema Mishra, Sushma Bhatnagar, Mukurdipi Ray, Suryanarayana Deo
BACKGROUND: Extensive surgical dissection, hemodynamic alterations associated with cytoreductive surgery (CRS), and hyperthermic intraperitoneal chemotherapy (HIPEC) make pain management challenging. We hypothesized that infusions of intravenous lignocaine and fentanyl provide comparable analgesia to epidural ropivacaine and fentanyl in these patients. METHODS: Fifty patients scheduled to undergo CRS and HIPEC were enrolled in the study. The patients in group IV (Intravenous) received a bolus dose of 1...
August 24, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/37605567/a-study-on-the-mechanism-of-action-of-yiqiyangyindecotion-for-the-treatment-of-diabetes-based-on-network-pharmacology
#37
JOURNAL ARTICLE
Ru Liu, Jing Xu, Qian Lu
To study the mechanism of action of YiQiYangYin decoction on diabetes mellitus by a network pharmacology method. The chemical components and targets of all the drugs in the YiQiYangYin decoction were obtained through the Traditional Chinese Medicine Systematic Pharmacology Database and Analysis Platform (TCMSP) and Traditional Chinese Medicine Integrated Database (TCMID), and the targets of diabetes were screened through the GeneCards and OMIM databases. The obtained targets were imported into Cytoscape 3.7...
June 30, 2023: Cellular and Molecular Biology
https://read.qxmd.com/read/37600432/iontophoresis-infused-deep-topical-anesthesia-and-injectable-local-anesthesia-for-dental-procedures-among-pediatric-patients-performances-and-consequences
#38
JOURNAL ARTICLE
Harsh Mistry, Shobha Fernandes, Md Ahsanul Haq, Yash Bafna, Rohan Bhatt, Susmita Sinha, Shreya Gajjar, Santosh Kumar, Mainul Haque
INTRODUCTION: Exploring routes of needle-free anesthesia has drawn particular attention to the iontophoretic technique. Iontophoresis has a wide range of applications in dentistry, treating hypersensitivity, oral ulcers, non-invasive procedures of deep topical anesthesia, etc. Hence, this research was performed for a comparative assessment of topical anesthesia spray infused via iontophoresis and local anesthesia (LA) infiltration for dental procedures among 5-12-year-old patients. MATERIALS AND METHODS: A split-mouth, randomized clinical trial was undertaken over two years among study subjects aged 5 to 12 years...
August 2023: Curēus
https://read.qxmd.com/read/37564844/comparison-of-landmark-guided-and-ultrasound-guided-technique-for-superior-laryngeal-nerve-block-to-aid-fibreoptic-intubation-an-observational-study
#39
JOURNAL ARTICLE
Nandini Basappa Magadum, Anitha Nileshwar, Vijayakumara
BACKGROUND AND AIMS: Awake fibreoptic intubation (AFOI) is the gold standard in the management of the difficult airway. Several methods to achieve airway anesthesia to aid AFOI include superior laryngeal nerve block (SLNB). This study aimed to compare land-mark-guided and ultrasound-guided techniques for SLNB to aid AFOI. MATERIAL AND METHODS: This was a prospective, observational study. Patients in both groups received 1 mg Midazolam and 50 μg of fentanyl for mild sedation before intubation, nasal passages were anaesthetized using lignocaine-coated nasopharyngeal airways, nebulization of 3 ml of 2% lignocaine, and intratracheal injection of 2 ml of 2% lignocaine given through cricothyroid membrane...
2023: Journal of Anaesthesiology, Clinical Pharmacology
https://read.qxmd.com/read/37564832/effects-of-bilateral-transmucosal-sphenopalatine-ganglion-block-on-intraoperative-anesthetic-requirements-and-recovery-profile-in-children-undergoing-palatoplasty-under-general-anesthesia
#40
JOURNAL ARTICLE
Sunil Rajan, Niranjan Kumar Sasikumar, Varsha Rudrahitlu, Jacob Mathew, Kaushik Barua, Lakshmi Kumar
BACKGROUND AND AIMS: Sphenopalatine ganglion block (SPGB) given as injection provides excellent perioperative analgesia during palatoplasty. Our objectives were to assess the effect of transmucosal SPGB on anesthetic requirements, intraoperative hemodynamics, recovery time, and emergence delirium in children undergoing palatoplasty. MATERIAL AND METHODS: This prospective, randomized study was conducted in 30 children with cleft palate undergoing palatoplasty, divided into two equal groups...
2023: Journal of Anaesthesiology, Clinical Pharmacology
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