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https://www.readbyqxmd.com/read/28538805/the-effect-of-epidurally-administered-dexamethasone-with-lignocaine-for-post-operative-analgesia-in-dogs-undergoing-ovariohysterectomy-a-dose-response-study
#1
Larissa Correa Hermeto, Rafael de Rossi, Natalia de Andrade Bicudo, Klebs Tavares Assis, Lucas Latta Escobar, Pedro Santana de Camargo
Purpose: To evaluate the postoperative analgesic and adverse effects of three doses of dexamethasone, administered epidurally in combination with lignocaine, in dogs undergoing ovariohysterectomy (OVH). Methods: Twenty-four female dogs undergoing ovariohysterectomy were pre-medicated with acepromazine and general anaesthesia was induced and maintained with propofol. Animals were randomly allocated into four groups of six. The control group was given lignocaine 2% (LI) and the treatment groups were given lignocaine with either 2 mg dexamethasone (LIDEX2), 4 mg dexamethasone (LIDEX4) or 8 mg dexamethasone (LIDEX8) administered at the lumbosacral epidural space...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28492789/single-dose-lignocaine-based-blood-cardioplegia-in-single-valve-replacement-patients
#2
Jaydip Ramani, Amber Malhotra, Vivek Wadhwa, Pranav Sharma, Pankaj Garg, Malkesh Tarsaria, Himani Pandya
OBJECTIVE: Myocardial protection is the most important in cardiac surgery. We compared our modified single-dose long-acting lignocaine-based blood cardioplegia with short-acting St Thomas 1 blood cardioplegia in patients undergoing single valve replacement. METHODS: A total of 110 patients who underwent single (aortic or mitral) valve replacement surgery were enrolled. Patients were divided in two groups based on the cardioplegia solution used. In group 1 (56 patients), long-acting lignocaine based-blood cardioplegia solution was administered as a single dose while in group 2 (54 patients), standard St Thomas IB (short-acting blood-based cardioplegia solution) was administered and repeated every 20 minutes...
March 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28460372/the-role-of-topiceuticals-in-cancer-pain
#3
Peter Paisley, Michael Serpell
PURPOSE OF REVIEW: Pain is one of the most common and feared symptoms associated with a new diagnosis of cancer and its subsequent treatment. Unfortunately, it remains undertreated in around one third of patients. It has been recently postulated that one mechanism for this could be failure to recognize neuropathic pain. One attractive option in both the case of neuropathic pain and pain associated with intolerable side effects of prescribed opioids is the use of 'topiceuticals', as a means of targeted pain relief with potentially fewer side effects...
June 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28439159/a-randomized-controlled-study-comparing-efficacy-of-classical-and-gow-gates-technique-for-providing-anesthesia-during-surgical-removal-of-impacted-mandibular-third-molar-a-split-mouth-design
#4
Nanjappa Madan, Kateel Shashidhara Kamath, A L Gopinath, A Yashvanth, Nagaraj Vaibhav, G Praveen
INTRODUCTION: Reliable profound mandibular block anesthesia is questionable when depositing the anesthetic solution at the lingula. The Gow-Gates technique is an useful alternative to the classical inferior alveolar nerve block and the incidence of unsuccessful anesthesia may be as high as classical technique. The aim of this study is to compare the clinical efficacy, degree of patient acceptability, advantages, disadvantages and limitations of the classical and Gow-Gates techniques for providing anesthesia in patients undergoing bilateral symmetrical surgical removal of impacted mandibular third molar under local anesthesia...
June 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28405129/effect-of-addition-of-fentanyl-and-clonidine-to-local-anesthetic-solution-in-peribulbar-block
#5
Poonam Nehra, Vrinda Oza, Vandana Parmar, Pooja Fumakiya
OBJECTIVE: To compare the effect of addition of fentanyl and clonidine as adjuvants to bupivacaine and lignocaine in peribulbar block. METHODS: The study was conducted on 105 adult patients of either sex, of ASA grade I and II undergoing ophthalmic surgeries. Patients were randomly divided into 3 groups of 35 each. All the patients were given peribulbuar block with 5ml lignocaine 2% +3 ml bupivacaine 0.5% +1 ml hyaluronidase (250 IU). In addition to this 1 ml normal saline was added to Group S, 25 μg fentanyl to Group F and 25 μg clonidine to Group C...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28393433/nasal-high-flow-oxygen-delivery-in-children-with-abnormal-airways
#6
Susan Humphreys, Derek Rosen, Tessa Housden, Julia Taylor, Andreas Schibler
BACKGROUND: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange has been shown to safely prolong the safe apnea time in well children post induction of anesthesia and is rapidly becoming a new standard for apneic oxygenation in adults. The same oxygenation technique is described as nasal high flow and can be used in infants and children at risk of apnea during anesthesia. AIM: We investigated the use of nasal high flow oxygen delivery during anesthesia in children with abnormal airways requiring tubeless airway assessment or surgery...
June 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28361827/comparative-antinociceptive-effect-of-arachidonylcyclopropylamide-a-cannabinoid-1-receptor-agonist-lignocaine-a-local-anaesthetic-agent-following-direct-intrawound-administration-in-rats
#7
Rahul Kumar, Pranav Prasoon, Mayank Gautam, Subrata Basu Ray
BACKGROUND & OBJECTIVES: Treatment of inflammatory pain with opioids is accompanied by unpleasant and, at times, life-threatening side effects.Cannabis produces antinociception as well as psychotropic effects. It was hypothesized that peripheral cannabinoid receptors outside the central nervous system could be selectively activated for relief of pain. This study was undertaken to measure the antinociceptive effect of type 1 cannabinoid receptor (CB1r) agonist arachidonylcyclopropylamide (ACPA) in a rat model of inflammatory pain after intrawound administration and the effects were compared with lignocaine...
November 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28356688/comparing-hemodynamic-and-glycemic-response-to-local-anesthesia-with-epinephrine-and-without-epinephrine-in-patients-undergoing-tooth-extractions
#8
Paramjot Kaur, Rashi Bahl, Sameer Kaura, Sumit Bansal
INTRODUCTION: Lignocaine with epinephrine as local anesthetic (LA) provides hemostasis and decreases the risk of systemic toxicity. The purpose of the present study was to investigate and compare the response of lignocaine with and without epinephrine to evaluate hemodynamic and metabolic response in normotensive and type II controlled diabetic patients. MATERIAL AND METHODS: A total of 50 patients (25 healthy and 25 controlled type II diabetics) undergoing multiple tooth extractions (age group of 20-80 years) were included in this prospective, randomised, clinical study...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28300684/a-prospective-study-of-the-role-of-intralesional-bleomycin-in-orbital-lymphangioma
#9
Nirav D Raichura, Md Shahid Alam, Veena Olma Noronha, Bipasha Mukherjee
PURPOSE: To evaluate the efficacy of intralesional bleomycin injection in the management of lymphangiomas of the orbit. METHODS: This prospective noncomparative interventional case study included 13 patients with orbital lymphangiomas. Reconstituted bleomycin 1-5 ml (0.5 IU/kg body weight; maximum, 15 IU/ml) was injected with 2% lignocaine in the lesion as seen on imaging or, in deeper lesions, under ultrasound guidance. Repeat injections were administered when required after every 4 weeks...
April 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28299268/role-of-addition-of-dexamethasone-to-lignocaine-2-with-adrenaline-in-dental-nerve-blocks-for-third-molar-surgery-a-prospective-randomized-control-trial
#10
Saroj Prasad Deo
CONTEXT: Dexamethasone has been frequently used in oral surgical procedure and accepted by oral and maxillofacial surgeon community worldwide. However, this is the first clinical trial that used dexamethasone as adjuvant with lignocaine in dental nerve block (DNB). AIMS: The purpose of this double-blind, randomized control trial (RCT) was to compare the effect of dexamethasone with normal saline (NS) in a lignocaine DNB. SETTINGS AND DESIGN: This prospective, double-blind, RCT was carried out after obtaining approval from the Institutional Ethical Committee...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28298790/effect-of-periradial-administration-of-papaverine-on-radial-artery-diameter
#11
P S Nagaraja, Naveen G Singh, N Manjunatha, Rushikesh Chintamanrao Desai
BACKGROUND: Radial artery cannulation is a skillful procedure. An experienced anesthesiologist might also face difficulty in cannulating a feeble radial pulse. AIM: The purpose of the study was to determine whether periradial subcutaneous administration of papaverine results in effective vasodilation and improvement in the palpability score of radial artery. SETTINGS AND DESIGN: Prospective, double-blinded trial. METHODOLOGY: Thirty patients undergoing elective cardiac surgery were enrolled in the study...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298788/effects-of-lignocaine-administered-intravenously-or-intratracheally-on-airway-and-hemodynamic-responses-during-emergence-and-extubation-in-patients-undergoing-elective-craniotomies-in-supine-position
#12
Tabasum Shabnum, Zulfiqar Ali, Imtiaz Ahmad Naqash, Aabid Hussain Mir, Khan Azhar, Syed Amer Zahoor, Abdul Waheed Mir
INTRODUCTION: Sympathoadrenergic responses during emergence and extubation can lead to an increase in heart rate (HR) and blood pressure whereas increased airway responses may lead to coughing and laryngospasm. The aim of our study was to compare the effects of lignocaine administered intravenously (IV) or intratracheally on airway and hemodynamic responses during emergence and extubation in patients undergoing elective craniotomies. METHODOLOGY: Sixty patients with physical status American Society of Anaesthesiologists Classes I and II aged 18-70 years, scheduled to undergo elective craniotomies were included...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298777/the-effectiveness-of-articaine-and-lidocaine-single-buccal-infiltration-versus-conventional-buccal-and-palatal-injection-using-lidocaine-during-primary-maxillary-molar-extraction-a-randomized-control-trial
#13
Naveen Kumar Reddy Kolli, S V S G Nirmala, Sivakumar Nuvvula
BACKGROUND: Despite the advent of modern injection techniques, palatal injection continues to be a painful experience for children. AIMS: To compare the pain experienced during extraction of maxillary primary molars with conventional lignocaine anesthesia versus lignocaine and articaine buccal infiltration in children aged 6-14 years. MATERIALS AND METHODS: A prospective randomized triple blinded study was conducted with ninety children (n = 90), randomly allocated to receive lignocaine conventional anesthesia (Group I [control group]), and buccal infiltration using articaine (Group II [articaine group]) or lignocaine (Group III [lignocaine group])...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298773/comparison-of-nerve-stimulation-guided-axillary-brachial-plexus-block-single-injection-versus-four-injections-a-prospective-randomized-double-blind-study
#14
Santoshi V Badiger, Sameer N Desai
BACKGROUND: A variety of techniques have been described for the axillary block using nerve stimulator, either with single injection, two, three, or four separate injections. Identification of all the four nerves is more difficult and time-consuming than other methods. AIMS: Aim of the present study is to compare success rate, onset, and duration of sensory and motor anesthesia of axillary block using nerve stimulator, either with single injection after identification of any one of the four nerves or four separate injections following identification of each of nerve...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298771/attenuation-of-hemodynamic-response-to-skull-pin-head-holder-insertion-intravenous-clonidine-versus-intravenous-lignocaine-infusion
#15
Nethra H Nanjundaswamy, Vinay Marulasiddappa
BACKGROUND: Insertion of skull pin induces a significant increase in heart rate (HR), blood pressure (BP) and intracranial pressure. Alpha 2 agonist clonidine and intravenous (i.v.) lignocaine are effective in attenuating stress response. Local infiltration of pin site and scalp block with lignocaine are commonly used techniques for prevention of hemodynamic response to skull pin insertion. We compared the effectiveness of i.v. clonidine infusion and i.v. lignocaine infusion in suppressing the hemodynamic response to skull pin head holder insertion...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298758/comparison-of-analgesic-efficacy-of-dexmedetomidine-and-midazolam-as-adjuncts-to-lignocaine-for-intravenous-regional-anesthesia
#16
Bharti Gupta, Ravinder Kumar Verma, Sudershan Kumar, Geeta Chaudhary
BACKGROUND: Intravenous regional anesthesia (IVRA) is safe, technically simple, and cost-effective technique compared to general anesthesia with success rates of 94-98% for upper and lower limb surgeries. The main disadvantage of this procedure is its limited duration for surgery, lack of postoperative analgesia, and tourniquet pain. To overcome this disadvantage, various adjuvants to lignocaine have been studied from time to time. AIM: To compare the analgesic efficacy of dexmedetomidine and midazolam as adjuncts to lignocaine for IVRA for forearm and hand surgeries...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298755/attenuation-of-cardiovascular-response-to-direct-laryngoscopy-and-intubation-comparative-study-of-lignocaine-nifedipine-and-placebo-during-general-anesthesia
#17
Venkata Sesha Sai Krishna Manne, Venkata Raghavendra Paluvadi
BACKGROUND/OBJECTIVE: The purpose of the study was to compare the attenuation of cardiovascular response to direct laryngoscopy and intubation using lignocaine, nifedipine, and placebo during general anesthesia. MATERIALS AND METHODS: This prospective study was done in sixty patients undergoing noncardiac surgeries of American Society of Anesthesiologists health status Class I and II between the age groups of 18-60 years. They were randomly divided into three groups of 20 each (lignocaine group, nifedipine group, and placebo group) and cardiovascular response (heart rate [HR] and blood pressure [BP]) to direct laryngoscopy and intubation were compared...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28274058/evaluation-of-efficacy-of-intraligamentary-injection-technique-for-extraction-of-mandibular-teeth-a-prospective-study
#18
Raunak Pradhan, Deepak Kulkarni, Lakshmi Shetty
INTRODUCTION: Fear of dental pain is one of the most common reasons for delaying dental treatment. Local Anaesthesia (LA) is the most commonly employed technique of achieving pain control in dentistry. Pterygomandibular Nerve Block (PNB), for achieving mandibular anaesthesia has been the traditional technique used and is associated with a few set of complications which include pain, nerve injury, trismus, and rarely facial nerve palsy, and sustained soft tissue anaesthesia. These complications have resulted in a rapid need for research on alternative local anaesthetic techniques...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28250482/efficacy-of-intravenous-dexmedetomidine-on-patient-s-satisfaction-comfort-and-sedation-during-awake-fibre-optic-intubation-in-patients-with-cervical-spondylotic-myelopathy-posted-for-elective-cervical-fixation
#19
Saikat Niyogi, Samir Basak, Amita Acharjee, Indrani Chakraborty
BACKGROUND AND AIMS: Various anaesthetic drugs, in addition to airway block, are used for producing favourable intubation conditions during awake fibre-optic intubation (AFOI), but most of them cause respiratory depression and hypoxaemia. The aim of this study was to evaluate the efficacy of intravenous (IV) dexmedetomidine (DEX) on sedation, patient comfort and cardiovascular responses during AFOI in patients with cervical spondylotic myelopathy (CSM). METHODS: This randomised, placebo-controlled, double-blinded, prospective study was conducted on 56 adult patients with cervical spondylotic myelopathy (CSM) undergoing elective cervical fixation, who were randomly allocated into two groups - Group D and Group C...
February 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28216910/effectiveness-of-paracervical-block-for-pain-relief-in-women-undergoing-hysterosalpingography
#20
Shikha Jain, Dattaprasad B Inamdar, Abha Majumdar, Deepak K Jain
OBJECTIVES: To evaluate the potential benefit, in terms of pain relief, of the paracervical block with 2% lignocaine in women undergoing hysterosalpingography (HSG). STUDY DESIGN: This study was a prospective randomized controlled study. SETTINGS: This study was conducted in infertility clinic of a tertiary care center. MATERIALS AND METHODS: Four hundred and six patients undergoing HSG as a part of infertility evaluation were included in the study...
October 2016: Journal of Human Reproductive Sciences
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