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https://www.readbyqxmd.com/read/29743284/vertebroplasty-versus-sham-procedure-for-painful-acute-osteoporotic-vertebral-compression-fractures-vertos-iv-randomised-sham-controlled-clinical-trial
#1
Cristina E Firanescu, Jolanda de Vries, Paul Lodder, Alexander Venmans, Marinus C Schoemaker, Albert J Smeet, Esther Donga, Job R Juttmann, Caroline A H Klazen, Otto E H Elgersma, Frits H Jansen, Alexander V Tielbeek, Issam Boukrab, Karen Schonenberg, Willem Jan J van Rooij, Joshua A Hirsch, Paul N M Lohle
OBJECTIVE: To assess whether percutaneous vertebroplasty results in more pain relief than a sham procedure in patients with acute osteoporotic compression fractures of the vertebral body. DESIGN: Randomised, double blind, sham controlled clinical trial. SETTING: Four community hospitals in the Netherlands, 2011-15. PARTICIPANTS: 180 participants requiring treatment for acute osteoporotic vertebral compression fractures were randomised to either vertebroplasty (n=91) or a sham procedure (n=89)...
May 9, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29739543/special-indications-for-opioid-free-anaesthesia-and-analgesia-patient-and-procedure-related-including-obesity-sleep-apnoea-chronic-obstructive-pulmonary-disease-complex-regional-pain-syndromes-opioid-addiction-and-cancer-surgery
#2
REVIEW
Adrian Sultana, David Torres, Roman Schumann
Opioid-free anaesthesia (OFA) is a technique where no intraoperative systemic, neuraxial or intracavitary opioid is administered with the anaesthetic. Opioid-free analgesia similarly avoids opioids in the perioperative period. There are many compelling reasons to avoid opioids in the surgical population. A number of case reports and, increasingly, prospective studies from all over the world support its benefits, especially in the morbidly obese population with or without sleep apnoea. A derivative technique is opioid sparing, where the same techniques are used but some opioid use is allowed...
December 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29666908/intravenous-local-anaesthetic-compared-with-intraperitoneal-local-anaesthetic-in-abdominal-surgery-a-systematic-review
#3
REVIEW
Wiremu S MacFater, Weisi Xia, Ahmed Barazanchi, Bruce Su'a, Darren Svirskis, Andrew G Hill
INTRODUCTION: Modern perioperative care strategies aim to optimise perioperative care by reducing the body's stress response to surgery. A major facet of optimising an abdominal surgery analgesia programme is using a multimodal opioid sparing approach. Local anaesthetics have shown promise and there has been considerable research into the most effective route for their administration. This review aims to determine if there is a difference in analgesic efficacy between intraperitoneal local anaesthetic (IPLA) and intravenous local anaesthetic (IVLA)...
April 17, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29643633/anesthetic-efficacy-of-4-articaine-and-2-lignocaine-in-achieving-palatal-anesthesia-following-a-single-buccal-infiltration-during-periodontal-therapy-a-randomized-double-blind-split-mouth-study
#4
Balachandran Ashwath, Sundaram Subramoniam, Rajaram Vijayalakshmi, Muthukali Shanmugam, Bagavathiperumal Meena Priya, Vijayarangan Anitha
Background: The aim of this randomized split-mouth double-blind study was to evaluate whether 4% articaine hydrochloride with 1:100,000 epinephrine administered as a single buccal infiltration in the maxillary posterior sextant can provide palatal anesthesia when compared with 2% lignocaine with 1:100,000 epinephrine during scaling and root planing and access flap surgery (AFS). Material and Methods: A total of 40 patients with chronic generalized periodontitis requiring periodontal therapy in the maxillary posterior sextants were recruited in this study...
January 2018: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29643620/opioid-free-anesthesia-for-breast-cancer-surgery-an-observational-study
#5
Swagata Tripathy, Satyajit Rath, Suresh Agrawal, P Bhaskar Rao, A Panda, T S Mishra, Sukdev Nayak
Background and Aims: Opioids are associated with postoperative nausea, vomiting, drowsiness, and increased analgesic requirement. A nonopioid anesthesia technique may reduce morbidity, enable day care surgery, and possibly decrease tumor recurrence. We compared opioid-free, nerve block-based anesthesia with opioid-based general anesthesia for breast cancer surgery in a prospective cohort study. Material and Methods: Twenty four adult American Society of Anesthesiologists grade I-III patients posted for modified radical mastectomy (MRM) with axillary dissection were induced with propofol and maintained on isoflurane (0...
January 2018: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29643556/a-prospective-observational-study-of-injection-pain-in-children-with-medium-plus-long-chain-triglyceride-and-long-chain-triglyceride-propofol-premixed-with-lignocaine
#6
Bhavika Singla, Anila D Malde
Background and Aims: Propofol injection pain is an unresolved problem in children. Although medium and long chain triglyceride (MCT-LCT) propofol has shown promising results in adults, its efficacy in children is not proven. In a prospective observational study the incidence and severity of pain with MCT-LCT and LCT propofol in children was compared. Methods: After obtaining approval from the Institutional Ethics Committee, 170 children (age group 6 months to 8 years) scheduled for various surgeries were included in this study...
March 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29628865/intranasal-lignocaine-spray-for-sphenopalatine-ganglion-block-for-postdural-puncture-headache
#7
Preksha Dubey, Prakash K Dubey
No abstract text is available yet for this article.
April 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29628834/comparison-of-analgesic-efficacy-and-safety-of-continuous-epidural-infusion-versus-local-infiltration-and-systemic-opioids-in-video-assisted-thoracoscopic-surgery-decortication-in-pediatric-empyema-patients
#8
Priyanka Pradeep Karnik, Nandini Malay Dave, Madhu Garasia
Introduction: The stripping of the densely innervated and inflamed parietal pleura in empyema during video-assisted thoracoscopic surgery (VATS) decortication can lead to significant pain and major postoperative respiratory compromise. Hence, we compared the analgesic efficacy of continuous epidural infusion versus local infiltration and systemic opioids in children undergoing VATS decortications. Methodology: Following ethics approval and informed consent, forty patients from 1 to 12 years of age were randomized into two groups, Group E (epidural) and Group L (local infiltration) after induction of anesthesia...
April 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29628705/ultrasound-guided-versus-landmark-guided-corticosteroid-injection-in-patients-with-rotator-cuff-syndrome-randomised-controlled-trial
#9
Himanshu Bhayana, Puneet Mishra, Anupama Tandon, Amite Pankaj, Rohit Pandey, Raskesh Malhotra
Objective: Impingement syndrome is the most common differential in a patient presenting to an orthopaedic OPD with shoulder pain. Impingement syndrome is often managed with subacromial corticosteroid injection, which can be instilled using either landmark guided (LMG) approach or with the assistance of ultrasound (US). This study was envisaged to enquire whether ultrasound assistance improves the accuracy, efficacy or safety profile of the injection. Methods: 60 patients of rotator cuff syndrome underwent diagnostic ultrasound...
March 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29628577/comparison-of-dexamethasone-and-buprenorphine-as-adjuvant-in-ultrasound-guided-brachial-plexus-blocks-a-randomized-controlled-trial
#10
Prasanna Vadhanan, Narendren Ganesh, M I Hussain Ahmed
Introduction: Effective postoperative analgesia is imperative for orthopedic surgeries to enhance recovery and facilitate early ambulation. Various additives have been used as adjuvants with local anesthetics in peripheral nerve blocks to provide postoperative analgesia. The aim of this study is to compare the duration of postoperative analgesia with buprenorphine and dexamethasone when administered as an adjuvant during ultrasound-guided brachial plexus blocks. Methodology: Sixty adult patients undergoing various upper arm surgeries were recruited for the study after acquiring ethics committee clearance...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29628574/effects-of-intravenous-and-inhaled-nebulized-lignocaine-on-the-hemodynamic-response-of-endotracheal-intubation-patients-a-randomized-clinical-trial
#11
Abolfazl Jokar, Maryam Babaei, Sahar Pourmatin, Majid Taheri, Amir Almasi-Hashiani, Arash Yazdanbakhsh
Background: Endotracheal intubation is one of the most common measures in the Intensive Care Unit (ICU) which plays an important role in airway management of the critically ill patients. Aims: The study aimed to evaluate the effects of lignocaine spray on hemodynamic response of endotracheal intubation patients. Settings and Design: This study is a randomized clinical trial on a study population comprising patients admitted to the ICU. Subjects and Methods: The patients were divided into three groups using a permuted block randomization...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29628554/comparison-of-ultrasound-with-peripheral-nerve-stimulator-guided-technique-for-supraclavicular-block-in-upper-limb-surgeries-a-randomized-controlled-trial
#12
Vinu Mervick Alfred, Gnanasekaran Srinivasan, Mamie Zachariah
Background: The supraclavicular approach is considered to be the easiest and most effective approach to block the brachial plexus for upper limb surgeries. The classical approach using the anatomical landmark technique was associated with higher failure rates and complications. Ultrasonography (USG) guidance and peripheral nerve stimulator (PNS) have improved the success rates and safety margin. Aims: The aim of the present study is to compare USG with PNS in supraclavicular brachial plexus block for upper limb surgeries with respect to the onset of motor and sensory blockade, total duration of blockade, procedure time, and complications...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29619784/comparison-between-lignocaine-nebulization-and-airway-nerve-block-for-awake-fiberoptic-bronchoscopy-guided-nasotracheal-intubation-a-single-blind-randomized-prospective-study
#13
Pooja Rawat Mathur, Neena Jain, Aji Kumar, Beena Thada, Veena Mathur, Deepak Garg
BACKGROUND: The preferred management strategy for difficult airways is awake fiberoptic bronchoscopy-guided intubation, which requires effective airway anesthesia to ensure patient comfort and acceptance. This randomized single-blind prospective study was conducted to compare lignocaine nebulization and airway nerve block for airway anesthesia prior to awake fiberoptic bronchoscopy-guided intubation. METHODS: Sixty adult patients scheduled for surgical procedures under general anesthesia were randomly allocated to two groups...
April 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29618887/comparison-of-ropivacaine-0-75-and-lignocaine-2-with-1-200-000-adrenaline-in-dental-extractions-single-blind-clinical-trial
#14
Vishal Bansal, Deval Kumar, Apoorva Mowar, Avi Bansal
Introduction: The aim of this study was to evaluate the efficacy, safety and clinical acceptability of the local anaesthetic agent ropivacaine 0.75 % in comparison with lignocaine 2 % with adrenaline 1:200,000 in minor oral surgical procedures. Methods: Forty-seven patients, who required bilateral extractions in a single arch, were included in this study. One hundred and sixty-six extractions were performed and all the patients were administered nerve blocks/infiltration...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29543062/benefits-of-pre-emptive-analgesia-by-local-infiltration-at-day-case-general-anaesthetic-open-inguinal-hernioplasty
#15
R W Radwan, A Gardner, H Jayamanne, B M Stephenson
Introduction The open prosthetic repair of inguinal hernias under local anaesthesia (LA) is well established, with the concept of intraoperative 'pre-emptive analgesia' evolving so that patients are as comfortable as possible. We used a peri-incisional LA solution in patients undergoing day-case inguinal hernioplasty under general anaesthesia (GA) and recorded use of analgesia in the immediate postoperative period. Methods In this observational cohort study, 100 consecutive unselected men underwent open inguinal hernia repair as a day case...
March 15, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29534614/analytical-evidence-to-show-letters-impregnated-with-novel-psychoactive-substances-are-a-means-of-getting-drugs-to-inmates-within-the-uk-prison-service
#16
Loretta T Ford, Jonathan D Berg
Introduction Novel psychotropic substances also known as legal highs are a major concern in UK prisons, fuelling violence and putting a strain on resources for inmates requiring medical treatment for adverse effects. We provide a clinical toxicology service including routine screening for novel psychoactive substances. In 2015, we were approached by Her Majesty Prison Service search dog training team to advise on which novel psychoactive substances to target, and again in 2016 to further provide analytical support to test five letters which the dogs positively identified for novel psychotropic substances during routine searches of prison mail rooms...
January 1, 2018: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/29491517/comparison-of-different-doses-of-intravenous-lignocaine-on-etomidate-induced-myoclonus-a-prospective-randomised-and-placebo-controlled-study
#17
Priyanka Gupta, Mayank Gupta
Background and Aims: Etomidate-induced myoclonus (EM) is observed in 50%-80% of unpremedicated patients. Low-dose lignocaine has been shown to attenuate but not abolish the EM. The aim of this prospective, randomised controlled study was to compare the different doses of lignocaine on the incidence and severity of EM. Methods: Two hundred adult patients were randomly assigned into four groups to receive saline placebo (Group I) or IV lignocaine 0.5 mg/kg (Group II), 1 mg/kg (Group III) or 1...
February 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29487243/a-survey-of-flexible-bronchoscopy-practices-in-india-the-indian-bronchoscopy-survey-2017
#18
Karan Madan, Anant Mohan, Ritesh Agarwal, Vijay Hadda, Gopi C Khilnani, Randeep Guleria
Background: There is a lack of contemporaneous data on the practices of flexible bronchoscopy in India. Aim: The aim of the study was to study the prevalent practices of flexible bronchoscopy across India. Methods: The "Indian Bronchoscopy Survey" was a 98-question, online survey structured into the following sections: general information, patient preparation and monitoring, sedation and topical anesthesia, procedural/technical aspects, and bronchoscope disinfection/staff protection...
March 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29485637/influence-of-tramadol-on-anaesthetic-indices-and-physiological-parameters-of-epidural-lignocaine-in-west-african-dwarf-sheep-undergoing-laparo-ovariectomy
#19
R A Ajadi, O A Sobanke, A A Adeniyi, A A Adeusi, A Adebiyi, A K Akinloye
The influence of tramadol on the anaesthetic indices and physiological parameters of epidural injection of lignocaine was evaluated in West African Dwarf (WAD) sheep undergoing laparo-ovariectomy. Ten female sheep weighing (16.2 ± 1.3 kg) were randomly allocated into anaesthesia with epidural injection of lignocaine (4mg/kg) (LIG), or lignocaine (2mg/kg) and tramadol (2mg/kg) (LIG-TRA). Following anaesthesia, they were aseptically prepared and subjected to laparo-ovariectomy. Behavioural changes were noted as they occur, and onset of drug action (OAN) (time between epidural injection and loss of pedal reflex), duration of analgesia (DAN) (time between disappearance and reappearance of pedal reflex) were determined...
December 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29440819/intravenous-lignocaine-infusion-for-intractable-pain-in-ewing-s-sarcoma
#20
Nivedita Page
A 23-year-old female presented to our palliative care center with Ewing's sarcoma of the humerus with lung metastases. Pain in her arm was unrelieved by nonsteroidal anti-inflammatory drugs, neuropathic medication as well as morphine. She could not tolerate any further increase in opioid dose but was so distraught due to the pain that she wanted to die. An intravenous lignocaine infusion in a dose of 2 mg/kg was given over an hour for three successive days. This successfully relieved her pain after which she was settled with her original medication...
January 2018: Indian Journal of Palliative Care
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