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Rheumatic Fever

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https://www.readbyqxmd.com/read/28926079/oklar-feber-hos-patient-med-ms-och-rituximab%C3%A2-behandling-var-neoehrlichios-ny-f%C3%A3-stingburen-infektion-som-%C3%A3-r-sv%C3%A3-r-att-diagnostisera
#1
Arya Dadgar, Anna Grankvist, Lennart Wernbro, Christine Wennerås
Fever of unknown origin in a multiple sclerosis patient on immunomodulatory therapy was due to neoehrlichiosis The emerging tick-borne bacterium Candidatus Neoehrlichia mikurensis is the etiologic agent of neoehrlichiosis, a febrile illness that may be accompanied by vascular complications. Severe cases of neoehrlichiosis have been described in patients with hematologic malignancies and systemic rheumatic diseases. We present the first case of neoehrlichiosis in a patient with multiple sclerosis undergoing rituximab therapy...
September 18, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28912780/inflammatory-markers-for-arterial-stiffness-in-cardiovascular-diseases
#2
REVIEW
Ioana Mozos, Clemens Malainer, Jarosław Horbańczuk, Cristina Gug, Dana Stoian, Constantin Tudor Luca, Atanas G Atanasov
Arterial stiffness predicts an increased risk of cardiovascular events. Inflammation plays a major role in large arteries stiffening, related to atherosclerosis, arteriosclerosis, endothelial dysfunction, smooth muscle cell migration, vascular calcification, increased activity of metalloproteinases, extracellular matrix degradation, oxidative stress, elastolysis, and degradation of collagen. The present paper reviews main mechanisms explaining the crosstalk between inflammation and arterial stiffness and the most common inflammatory markers associated with increased arterial stiffness, considering the most recent clinical and experimental studies...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28906537/the-changing-spectrum-of-rheumatic-mitral-regurgitation-in-soweto-south-africa
#3
Ruchika Meel, Ferande Peters, Elena Libhaber, Mohammed Rafique Essop
OBJECTIVES: To determine the clinical and echocardiographic characteristics of contemporary patients with rheumatic mitral regurgitation (MR) at Chris Hani Baragwanath Academic Hospital. METHODS: This prospective, cross-sectional study included 84 patients with isolated moderate or severe rheumatic MR who underwent clinical and echocardiographic assessment. RESULTS: Mean age of the patients was 44 ± 15.3 years (84% females). Acute rheumatic fever was rare...
July 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28859047/childhood-blastic-plasmacytoid-dendritic-cell-neoplasm-mimicking-acute-rheumatic-fever-report-of-an-unusual-clinical-presentation-and-review-of-literature
#4
Banashree Devi Rajkumari, Vinay Munikoty, Sreejesh Sreedharanunni, Richa Jain, Man Updesh Singh Sachdeva, Neelam Varma
BACKGROUND: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is very rarely diagnosed in children with less than 50 cases in the literature. OBSERVATION: We report a case of childhood BPDCN who mimicked acute rheumatic fever at presentation. Majority of the reported childhood BPDCN received acute lymphoblastic leukemia-like chemotherapy with/without stem cell therapy, whereas those who received acute myeloid leukemia-like therapy predominantly succumbed to disease or sepsis...
August 30, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28796771/is-a-rheumatic-fever-register-the-best-surveillance-tool-to-evaluate-rheumatic-fever-control-in-the-auckland-region
#5
Te Aro Moxon, Peter Reed, Timothy Jelleyman, Philippa Anderson, Alison Leversha, Catherine Jackson, Diana Lennon
AIM: To determine the most accurate data source for acute rheumatic fever (ARF) epidemiology in the Auckland region. METHOD: To assess coverage of the Auckland Regional Rheumatic Fever Register (ARRFR), (1998-2010) for children <15 years and resident in Auckland at the time of illness, register, hospitalisation and notification data were compared. A consistent definition was applied to determine definite and probable cases of ARF using clinical records. (www...
August 11, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28796768/emm-type-distribution-of-group-a-streptococcus-isolates-from-the-throat-swabs-of-children-living-in-areas-with-a-high-northland-and-gisborne-or-low-palmerston-north-incidence-of-acute-rheumatic-fever
#6
COMPARATIVE STUDY
Noah Mhlanga, Grace Sharp, Mary Nulsen
AIM: To assess the circulating emm types of pharyngeal isolates of group A streptococcus (GAS) among school children living in Northland, the Gisborne region and Palmerston North, New Zealand. METHODS: GAS were isolated from throat swabs sent to laboratories in Northland (197 in 2013) and Gisborne (115 in 2014-15) and from children enrolled in the Palmerston North Solar Ventilation Project (70 in 2013-14). The incidences of acute rheumatic fever (ARF) cases in the three regions in 2014 were 9, 19...
August 11, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28796766/rheumatic-fever-as-an-indicator-of-child-health
#7
EDITORIAL
Diana Lennon
No abstract text is available yet for this article.
August 11, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28795446/tricuspid-valve-replacement-with-mechanical-prostheses-short-and-long-term-outcomes
#8
Xavier Rossello, Christian Muñoz-Guijosa, Elisabet Mena, Marta Camprecios, Ana B Mendez, Xavier Borras, Josep M Padro
BACKGROUND AND AIM: Tricuspid valve replacement has been associated with high mortality and poor long-term outcomes. We report the preoperative risk factors associated with short and long-term outcomes following tricuspid valve replacement with mechanical prostheses. METHODS: In 62 patients who underwent mechanical tricuspid valve replacement, clinical, laboratory, and echocardiographic findings were analyzed using both univariate and multivariate analyses to describe operative and long-term mortality...
September 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28776364/jaccoud-s-arthropathy-an-unusual-manifestation-of-idiopathic-retroperitoneal-fibrosis-rapid-improvement-of-symptoms-after-tocilizumab-treatment
#9
M Benucci, A Damiani, F Li Gobbi, V Grossi, M Infantino, A Arena, M Manfredi
Jaccoud's arthropathy (JA) is a chronic, non erosive, rheumatoid-like deformity associated with rheumatic fever (RF) and systemic lupus erythematosus and with other diseases such as psoriatic arthritis, connective tissue diseases, hypocomplementemic urticarial vasculitis, infections, sarcoidosis and neoplasia. We described a case of JA in a patient with cutaneous psoriasis but with a particular disease evolution associated with idiopathic retropritoneal fibrosis (IRF), evaluated with computed tomography, magnetic resonance and 18F-FDG PET/ CT...
August 3, 2017: Reumatismo
https://www.readbyqxmd.com/read/28768449/recurrent-fuo-due-to-intermittent-enterobacter-cloacae-bacteremias-from-an-infected-pacemaker-lead-diagnosed-by-gallium-scan
#10
Burke A Cunha, Ismail Jimada
Fever of unknown origin (FUO) refers to fevers of ≥101° F that persist for ≥3 weeks and remain undiagnosed after a focused inpatient or outpatient workup. FUO may be due to infectious, malignant/neoplastic, rheumatic/inflammatory, or miscellaneous disorders. Recurrent FUOs are due to the same causes of classical FUOs. Recurrent FUOs may have continuous or intermittent fevers and are particularly difficult to diagnose. With intermittent fever, recurrent FUO diagnostic tests are best obtained during fever episodes...
August 2, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28749400/a-novel-approach-for-characterizing-variations-in-serum-peptides-in-rheumatic-heart-disease
#11
Xiaochen Wu, Qin Yue, Weikun Jia, Jinbao Zhang, Hui Ouyang, Dong Xin, Yingbin Xiao
BACKGROUND & OBJECTIVES: Acute rheumatic fever and rheumatic heart disease (RHD) are important public health problems in developing countries. In this study, peptidomic analyses on RHD patients and healthy individuals were performed to characterize variations in serum peptide levels using label-free quantitation approaches. METHODS: Blood samples were obtained from 160 healthy controls and 160 RHD patients. Of the 448 identified peptides, 272 were analyzed by two label-free mass spectrometry methods, the spectral count and spectral index...
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28745221/rheumatic-heart-disease-pathogenesis-and-vaccine
#12
L Guilherme, S Freschi de Barros, K F Köhler, S R Santos, F Morais Ferreira, W R Silva, R Alencar, E Postol, J Kalil
Rheumatic fever (RF) and rheumatic heart disease (RHD) follow untreated S. pyogenes throat infections in children who present susceptible genes that favor the development of autoimmune reactions. In this review, we focus on the genes that confer susceptibility and on the autoimmune reactions that occur due to molecular mimicry between human-tissue proteins and streptococcal M protein. Polyarthritis is the initial manifestation, which can evolve to carditis and severe valve damage; these culminate in rheumatic heart disease (RHD) or Sydenham's chorea, which affects the central nervous system...
July 25, 2017: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28743364/rheumatic-fever-update-on-the-jones-criteria-according-to-the-american-heart-association-review-2015
#13
Breno Álvares de Faria Pereira, Alinne Rodrigues Belo, Nilzio Antônio da Silva
Rheumatic fever is still currently a prevalent disease, especially in developing countries. Triggered by a Group A β-hemolytic Streptococcus infection, the disease may affect genetically predisposed patients. Rheumatic carditis is the most important of its clinical manifestations, which can generate incapacitating sequelae of great impact for the individual and for society. Currently, its diagnosis is made based on the Jones criteria, established in 1992 by the American Heart Association. In 2015, the AHA carried out a significant review of these criteria, with new diagnostic parameters and recommendations...
July 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28741863/development-of-quality-metrics-for-ambulatory-pediatric-cardiology-infection-prevention
#14
Jonathan N Johnson, Cindy S Barrett, Wayne H Franklin, Eric M Graham, Nancy J Halnon, Brandy A Hattendorf, Catherine D Krawczeski, James J McGovern, Matthew J O'Connor, Amy H Schultz, Jeffrey M Vinocur, Devyani Chowdhury, Jeffrey B Anderson
INTRODUCTION: In 2012, the American College of Cardiology's (ACC) Adult Congenital and Pediatric Cardiology Council established a program to develop quality metrics to guide ambulatory practices for pediatric cardiology. The council chose five areas on which to focus their efforts; chest pain, Kawasaki Disease, tetralogy of Fallot, transposition of the great arteries after arterial switch, and infection prevention. Here, we sought to describe the process, evaluation, and results of the Infection Prevention Committee's metric design process...
July 25, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28741853/application-of-nir-spectroscopy-coupled-with-pls-regression-for-quantification-of-total-polyphenol-contents-from-the-fruit-and-aerial-parts-of-citrullus-colocynthis
#15
Tania S Rizvi, Fazal Mabood, Liaqat Ali, Mohammed Al-Broumi, Hamida K M Al Rabani, Javid Hussain, Farah Jabeen, Suryyia Manzoor, Ahmed Al-Harrasi
INTRODUCTION: Citrullus colocynthis (L.) Schrad is extensively used to treat diabetes, obesity, fever, cancer, amenorrhea, jaundice, leukemia, rheumatism, and respiratory diseases. Chemical studies have indicated the presence of several cucurbitacins, flavones, and other polyphenols in this plant. These phytochemical constituents are responsible for the interesting antioxidant and other biological activities of C. colocynthis. OBJECTIVE: In the present study, for the first time, near infrared (NIR) spectroscopy coupled with partial least square (PLS) regression analysis was used to quantify the polyphenolic phytochemicals of C...
July 25, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28721865/eliminating-acute-rheumatic-fever-and-rheumatic-heart-disease
#16
Magdi Yacoub, Bongani Mayosi, Ahmed ElGuindy, Alain Carpentier, Salim Yusuf
No abstract text is available yet for this article.
July 15, 2017: Lancet
https://www.readbyqxmd.com/read/28720034/rheumatic-fever-presenting-as-recurrent-pericarditis-and-cardiac-tamponade
#17
Ashley Howard, Lisa Sutton Md, Jaime Fergie
No abstract text is available yet for this article.
August 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28683722/epidemiology-of-pharyngitis-as-reported-by-zambian-school-children-and-their-families-implications-for-demand-side-interventions-to-prevent-rheumatic-heart-disease
#18
John Musuku, Joyce C Lungu, Elizabeth Machila, Catherine Jones, Laurence Colin, Sherri Schwaninger, Patrick Musonda, Brigitta Tadmor, Jonathan M Spector, Mark E Engel, Liesl J Zühlke
BACKGROUND: Prompt and appropriate treatment of streptococcal pharyngitis decreases the risk of acute rheumatic fever and rheumatic heart disease (RHD). Understanding public perceptions and behaviors related to sore throat is fundamental to inform health programs aimed at eliminating new cases of RHD in endemic regions. We sought to describe the epidemiology of pediatric pharyngitis and its treatment, as reported by children and their parents or guardians in Lusaka, Zambia. METHODS: This was a cross-sectional investigation using interviews and written surveys, nested in a school-based RHD prevalence study...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28681803/molecular-biology-of-group-a-streptococcus-and-its-implications-in-vaccine-strategies
#19
REVIEW
N K Brahmadathan
Infections due to Streptococcus pyogenes and their complications are a problem of major concern in many countries, including India. Primary prophylaxis with benzathine penicillin is the key to control and prevent sequelae such as acute rheumatic fever and rheumatic heart disease (RF/RHD) or post-streptococcal glomerulonephritis (PSGN). Non-compliance to prophylaxis due to fear of injection and anaphylaxis is major issues in RF/RHD control in India and leads to continued high prevalence of infection and post-streptococcal sequelae...
April 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28673022/secondary-prevention-for-screening-detected-rheumatic-heart-disease-opportunities-to-improve-adherence
#20
Daniel Engelman, Maureen Ah Kee, Reapi L Mataika, Joseph H Kado, Samantha M Colquhoun, Jim Tulloch, Andrew C Steer
Background: Secondary prevention is an effective treatment for rheumatic heart disease (RHD), but ensuring high adherence to prophylaxis over many years is challenging and requires understanding of local factors. Methods: Participants were young people diagnosed with RHD through echocardiographic screening in Fiji. We used a structured interview to evaluate the following: health seeking behaviours; attitudes, practice, barriers and potential improvement strategies for adherence to antibiotic prophylaxis; and adolescent-friendly qualities of the health service...
April 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
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