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https://www.readbyqxmd.com/read/29243674/turmeric-a-condiment-cosmetic-and-cure
#1
REVIEW
Hima Gopinath, Kaliaperumal Karthikeyan
Turmeric (Curcuma longa L.) is an integral part of Asian culture and cuisine. It has been used in traditional medicine since centuries. A myriad of health benefits have been attributed to it. Curcumin, the most biologically active curcuminoid in turmeric, is being investigated in pre-clinical and clinical trials for its role in disease prevention and cure. It has antioxidant, anti-inflammatory, antineoplastic, anti-proliferative and antimicrobial effects. We review the chemistry of this plant, its cultural relevance in Indian skin care, and its uses in dermatology...
December 14, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29234442/the-association-of-quantitative-facial-color-features-with-cold-pattern-in-traditional-east-asian-medicine
#2
Sujeong Mun, Ilkoo Ahn, Siwoo Lee
Introduction: Facial diagnosis is a major component of the diagnostic method in traditional East Asian medicine. We investigated the association of quantitative facial color features with cold pattern using a fully automated facial color parameterization system. Methods: The facial color parameters of 64 participants were obtained from digital photographs using an automatic color correction and color parameter calculation system. Cold pattern severity was evaluated using a questionnaire...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29226039/an-inner-city-emergency-medicine-rotation-does-not-improve-attitudes-toward-the-homeless-among-junior-medical-learners
#3
Aaron Sibley, Kathryn A Dong, Brian H Rowe
Introduction Learners in the emergency department (ED) frequently encounter individuals who are homeless. We sought to evaluate the effect of an inner city emergency medicine rotation at the Royal Alexandra Hospital (RAH) on the attitudes of medical students and residents towards this population. Methods Data were collected both pre- and post-rotation using an electronic survey. Data collected included demographic information and as well as scores on the Health Professionals' Attitudes Towards the Homeless Inventory (HPATHI)...
October 5, 2017: Curēus
https://www.readbyqxmd.com/read/29224365/evaluation-of-genotoxic-and-modulatory-effects-of-nyctanthes-arbor-tristis-calyx-extract-and-the-isolated-crocin-in-ames-assay
#4
Neha Pawar, Shital Panchal, Dhananjay Kawle, Chhaya Gadgoli, Girish Maru
Flowers of the plant Nyctanthes arbor-tristis (NAT) are widely used in the traditional medicinal systems of several Asian countries. In the present study, potential genotoxicity and modulatory effects of ethanolic extract of NAT flower calyx (NAT FCE) and crocin, a carotenoid principle were evaluated employing standard Salmonella assay. Experiments evaluating the genotoxic potential of NAT FCE and crocin, with and without the S9-activation in TA 98, TA 100 and TA 102 showed a lack of increase in revertant mutants...
December 11, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29217726/the-association-between-the-use-of-biomedical-services-and-the-holistic-use-of-traditional-east-asian-medicine-a-national-survey-of-outpatients-in-south-korea
#5
Jae-Mahn Shim, Yun-Suk Lee
OBJECTIVES: The holistic use of a system of complementary and alternative medicine (CAM) is potentially linked to its treatment outcomes. This paper examines how the use of biomedicine is associated with the holistic use of CAM, focusing on traditional East Asian medicine (EM) that is uniquely integrated in the medical system in South Korea. DESIGN/SETTINGS: A representative national sample of EM outpatients in South Korea. PARTICIPANTS: 3861 survey respondents...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29209958/moxibustion-therapy-in-traditional-mongolian-medicine
#6
Tae-Hun Kim, Do-Hoon Kim, Seong Gyu Lee
From the medical history of traditional Eastern Asian and Tibetan medicine, the origin and development of moxibustion seems to be closely related to Mongolia. To explore the current clinical practice of moxibustion in Mongolia, we visited a teaching hospital, the Traditional Medical Science, Technology and Production Corporation of Mongolia, in February 2014. Many types of moxibustion are found to be used, and various modalities and methods are practiced based on the principles of traditional Mongolian medicine...
December 5, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29209457/anti-fibrotic-effects-of-orostachys-japonicus-a-berger-crassulaceae-on-hepatic-stellate-cells-and-thioacetamide-induced-fibrosis-in-rats
#7
Sushruta Koppula, Mun-Jeong Yum, Jin-Seoub Kim, Gwang-Mo Shin, Yun-Jin Chae, Tony Yoon, Chi-Su Chun, Jae-Dong Lee, MinDong Song
BACKGROUND/OBJECTIVE: Orostachys japonicus A. Berger (Crassulaceae) has been used in traditional herbal medicines in Korea and other Asian countries to treat various diseases, including liver disorders. In the present study, the anti-fibrotic effects of O. japonicus extract (OJE) in cellular and experimental hepatofibrotic rat models were investigated. MATERIALS/METHODS: An in vitro hepatic stellate cells (HSCs) system was used to estimate cell viability, cell cycle and apoptosis by MTT assay, flow cytometry, and Annexin V-FITC/PI staining techniques, respectively...
December 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/29206203/de-novo-rna-sequencing-and-expression-analysis-of-aconitum-carmichaelii-to-analyze-key-genes-involved-in-the-biosynthesis-of-diterpene-alkaloids
#8
Megha Rai, Amit Rai, Noriaki Kawano, Kayo Yoshimatsu, Hiroki Takahashi, Hideyuki Suzuki, Nobuo Kawahara, Kazuki Saito, Mami Yamazaki
Aconitum carmichaelii is an important medicinal herb used widely in China, Japan, India, Korea, and other Asian countries. While extensive research on the characterization of metabolic extracts of A. carmichaelii has shown accumulation of numerous bioactive metabolites including aconitine and aconitine-type diterpene alkaloids, its biosynthetic pathway remains largely unknown. Biosynthesis of these secondary metabolites is tightly controlled and mostly occurs in a tissue-specific manner; therefore, transcriptome analysis across multiple tissues is an attractive method to identify the molecular components involved for further functional characterization...
December 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29204385/evidence-based-review-grade-of-recommendation-and-suggested-treatment-recommendations-for-melasma
#9
Nilendu Sarma, Sayantani Chakraborty, Shital A Poojary, Sanjay Rathi, Sendhil Kumaran, Balakrishnan Nirmal, Joan Felicita, Rashmi Sarkar, Prashansa Jaiswal, Paschal D'Souza, Nagaraju Donthula, Sumit Sethi, Pallavi Ailawadi, Bebisha Joseph
Treatment of melasma is known to be less satisfactory, often incomplete, and relapse is frequent. Although many treatment options are available, they are either known to be unsafe on long-term use or their long-term safety profile is unknown. Patients often use various drugs, even topical steroid-based preparation without any medical supervision for long period of time, making the skin unsuitable for many of the drugs available. Thus, there has been gross disparity among the treating physician about what drugs and what regimen are best suitable for various categories of melasma patients and in different situations...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29203273/the-traditional-use-of-vachellia-nilotica-for-sexually-transmitted-diseases-is-substantiated-by-the-antiviral-activity-of-its-bark-extract-against-sexually-transmitted-viruses
#10
Manuela Donalisio, Valeria Cagno, Andrea Civra, Davide Gibellini, Giuseppina Musumeci, Massimo Rittà, Manik Ghosh, David Lembo
ETHNOPHARMACOLOGICAL RELEVANCE: Vachellia (Acacia) nilotica and other plants of this genus have been used in traditional medicine of Asian and African countries to treat many disorders, including sexually transmitted diseases, but few studies were performed to validate their anti-microbial and anti-viral activity against sexually transmitted infections. AIM OF THE STUDY: The present study was undertaken to explore whether the ethnomedical use of V.nilotica to treat genital lesions is substantiated by its antiviral activity against the human immunodeficiency virus (HIV), the herpes simplex virus (HSV) and the human papillomavirus (HPV)...
December 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29202423/suicide-and-self-harm-in-nepal-a-scoping-review
#11
REVIEW
Suresh Thapaliya, Pawan Sharma, Kapil Upadhyaya
BACKGROUND: Suicide and self harm behavior has become a major public health issue in recent years in Nepal. This small south Asian country was ranked 7th by suicide rate globally by the 2014 World Health Organization report with an estimated 6,840 suicides annually, or 24.9 suicides per 100,000 people. We decided to explore the epidemiology of suicidal behaviour and self harm, modes of attempt, associated risk factors and trends in specific population. METHODOLOGY: Two researchers independently reviewed 47 studies published in the US National Library of Medicine's PubMed electronic Database and Google Scholar till December 2016...
December 1, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29201778/liver-disease-in-sri-lanka
#12
REVIEW
Hasitha S Wijewantha
Liver disease in Sri Lanka is mainly due to alcoholic liver disease and nonalcoholic fatty liver disease. In contrast to other South Asian countries, the prevalence of hepatitis B and C is low in Sri Lanka and prevalence of hepatitis A is intermediate. The few reported cases of hepatitis E in Sri Lanka are mainly in people who have traveled to neighboring South Asian countries. Wilson's disease, autoimmune hepatitis, hemochromatosis, drug-induced liver disease, and primary biliary cirrhosis are recognized causes of liver disease in Sri Lanka...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29200714/simultaneous-determination-of-ten-constituents-in-chaiqin-qingning-capsule-by-high-performance-liquid-chromatography-coupled-with-triple-quadrupole-mass-spectrometry
#13
Ting Yu Li, Xiao Kui Huo, Lu Zheng, Chao Wang, Hai Jian Cong, Ting Xiang, Lin Zhang, Bao Jing Zhang, Shan Shan Huang, Bin Wu, Xin Yu Li
Background: Chaiqin Qingning Capsule (CQQNC) was a prescription of Traditional Chinese Medicine with the effects of clearing away heat and removing toxin, harmonizing the exterior and interior, it was widely used in Asian, for example, China and Japan, different batches of the raws materials and different processing time may be the vital factor which raised a challenge to control the quality of the CQQNC. Experimental Methods: In this experiment, a high-performance liquid chromatography-mass spectrometry/MS (HPLC-MS/MS) method was developed to simultaneously determine ten bioactive components for the quality control of CQQNC...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29198424/the-uterine-fibroid-myoma-tumour-analysis-of-the-global-research-architecture-using-density-equalizing-mapping
#14
Dörthe Brüggmann, Frank Louwen, Tatjana Braun, Doris Klingelhöfer, Jan Bauer, Michael H Bendels, Matthias Bundschuh, David Quarcoo, Jenny Jaque, Eileen M Wanke, David A Groneberg
Uterine fibroids can severely impact a woman's quality of life, result in significant morbidity and are a leading indication for hysterectomy. Many aspects of the disease remain largely obscure. Despite these knowledge gaps, no detailed maps of the global fibroid research architecture have yet been generated. This study used the NewQIS approach to assess worldwide research productivity, encompassing numerous aspects of the scientific output, quality and socioeconomic features. Regression analysis indicated an increase in fibroid research activity in the investigated time periods...
November 15, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29197368/an-asian-traditional-herbal-complex-containing-houttuynia-cordata-thunb-perilla-frutescens-var-acuta-and-green-tea-stimulates-hair-growth-in-mice
#15
Mun Su Chung, Woong Jin Bae, Sae Woong Choi, Kyu Won Lee, Hyun Cheoul Jeong, Fahad Bashraheel, Seung Hwan Jeon, Jin Woo Jung, Byung Il Yoon, Eun Bi Kwon, Hyun A Oh, Sung Yeoun Hwang, Sae Woong Kim
BACKGROUND: Houttuynia cordata Thunb (HC) is a traditional herbal medicine widely used in Asia for the treatment of patients with alopecia, usually in combination with other two herbal medicines (Perilla frutescens var. acuta (PFVA) and green tea (GT)). However, the effect of this herbal complex has not been clearly demonstrated. We sought to determine the hair growth-promoting effect of this herbal complex (HC, PFVA, and GT) in the animal model. METHODS: Six-week-old male C57BL/6 mice were randomly divided into four groups (negative control, finasteride (1 mg/kg) as a positive control, and two (200 and 400 mg/kg) concentrations of the herbal complex as experimental groups) and were fed its corresponding medications orally for 25 days...
December 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29183812/muli-bamboo-melocanna-baccifera-leaves-ethanolic-extract-a-non-toxic-phyto-prophylactic-against-low-ph-stress-and-saprolegniasis-in-labeo-rohita-fingerlings
#16
Md Idrish Raja Khan, Ratan Kumar Saha, Himadri Saha
Bamboo (Melocanna baccifera) plant plays a significant role in traditional Asian medicine and it can be used as an alternative to various chemo-therapeutics or prophylactic agents used in aquaculture. In the present study, the first experiment was done for the preparation of extracts from bamboo leaves by using 90% alcohol as a solvent. In the 2nd experiment, toxicity study was carried on Labeo rohita fingerlings (average length of 10.3 ± 1.5 cm and weight 18.5 ± 1.5 g) using BLAL (Bamboo Leaf Alcoholic) extract and it did not show any mortalities in fish even at the dose of 20 g kg-1 body weight, which can be regarded as virtually non-toxic with minimal effect...
November 25, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29183271/compulsory-licensing-of-pharmaceuticals-reconsidered-current-situation-and-implications-for-access-to-medicines
#17
Kyung-Bok Son, Tae-Jin Lee
To examine patterns and trends in attempts, distinguished from issuance, to issue compulsory licensing of pharmaceuticals and to assess related implications in the era of high-cost medicines. Documents from various civil society organisations were primarily used to search attempts, as well as published literature. The identified attempts were analysed by pharmaceutical level, national level, claimers, and the outcomes of the attempts. There have been 108 attempts to issue compulsory licensing for 40 pharmaceuticals in 27 countries since 1995...
November 28, 2017: Global Public Health
https://www.readbyqxmd.com/read/29179688/evaluating-genetic-ancestry-and-self-reported-ethnicity-in-the-context-of-carrier-screening
#18
Roman Shraga, Sarah Yarnall, Sonya Elango, Arun Manoharan, Sally Ann Rodriguez, Sara L Bristow, Neha Kumar, Mohammad Niknazar, David Hoffman, Shahin Ghadir, Rita Vassena, Serena H Chen, Avner Hershlag, Jamie Grifo, Oscar Puig
BACKGROUND: Current professional society guidelines recommend genetic carrier screening be offered on the basis of ethnicity, or when using expanded carrier screening panels, they recommend to compute residual risk based on ethnicity. We investigated the reliability of self-reported ethnicity in 9138 subjects referred to carrier screening. Self-reported ethnicity gathered from test requisition forms and during post-test genetic counseling, and genetic ancestry predicted by a statistical model, were compared for concordance...
November 28, 2017: BMC Genetics
https://www.readbyqxmd.com/read/29174375/actinidia-arguta-extract-attenuates-inflammasome-activation-potential-involvement-in-nlrp3-ubiquitination
#19
Kang-Hyuck Heo, Xiao Sun, Do-Wan Shim, Myong-Ki Kim, Sushruta Koppula, Sang-Hyeun Yu, Han-Bi Kim, Tack-Joong Kim, Tae-Bong Kang, Kwang-Ho Lee
ETHNOPHARMACOLOGICAL RELEVANCE: Actinidia arguta (A. arguta) has been widely used in Asian countries as a traditional medicinal herb to treat inflammation-related diseases, such as gastritis, bronchitis, and arthritis. AIM OF THE STUDY: The inhibitory effect of A. arguta leaves' extract (AA) on inflammasome activation was investigated to verify its traditional use in treating inflammation-related diseases. MATERIALS AND METHODS: Bone marrow-derived macrophages (BMDMs) primed by lipopolysaccharide (LPS) were activated by selective inflammasome stimulators, and the effect of AA on inflammasome activation was investigated...
November 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29173101/advancing-global-precision-medicine-an-overview-of-genomic-testing-and-counseling-services-in-malaysia
#20
Angeliki Balasopoulou, Foong-Ming Mooy, Darrol J Baker, Christina Mitropoulou, Efthymios Skoufas, Awang Bulgiba, Theodora Katsila, George P Patrinos
Precision medicine, genomic and diagnostic services are no longer limited to developed countries. This broadening in geography of biomarker applications and omics diagnostics also demands empirical study of implementation, diagnostic testing, and counseling practices in the field. For example, the Malaysian population has large ethnic diversity and high prevalence of genetic disorders such as hemoglobinopathies and metabolic disorders. Increased morbidity and mortality from such diseases have a direct impact on society and health system sustainability and for this, decision-making becomes of outmost importance...
November 27, 2017: Omics: a Journal of Integrative Biology
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