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https://www.readbyqxmd.com/read/28341950/frontal-changes-in-the-lower-face-after-clockwise-rotation-of-the-maxillomandibular-complex-without-perisurgical-orthodontic-treatment-in-angle-class-i-and-skeletal-class-iii-women
#1
Sang Woo Lee, Jeongmok Cho, Kikap Kim, Seung Hyun Ahn
BACKGROUND: Orthognathic surgery has become more popular to slenderize a wide lower face and to improve facial esthetics in Asian patients with normal occlusion. Clockwise rotation (CR) of the maxillomandibular complex (MMC) steepens the mandibular plane. This study performed a quantitative analysis on the influence of CR on slenderness of the lower face from the frontal view. PATIENTS AND METHODS: This retrospective study included 36 female patients with Angle Class I occlusion and skeletal Class III pattern...
March 24, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28335885/policy-and-priorities-for-national-cancer-control-planning-in-low-and-middle-income-countries-lessons-from-the-association-of-southeast-asian-nations-asean-costs-in-oncology-prospective-cohort-study
#2
(no author information available yet)
BACKGROUND: Evidence to guide policymakers in developing affordable and equitable cancer control plans are scarce in low- and middle-income countries (LMIC). METHODS: The 2012-2014 ASEAN Costs in Oncology Study prospectively followed-up 9513 newly diagnosed cancer patients from eight LMIC in Southeast Asia for 12 months. Overall and country-specific incidence of financial catastrophe (out-of-pocket health costs ≥ 30% of annual household income), economic hardship (inability to make necessary household payments), poverty (living below national poverty line), and all-cause mortality were determined...
March 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28322971/effects-and-mechanisms-of-compound-chinese-medicine-and-major-ingredients-on-microcirculatory-dysfunction-and-organ-injury-induced-by-ischemia-reperfusion
#3
REVIEW
Jing-Yan Han, Quan Li, Zhi-Zhong Ma, Jing-Yu Fan
Microcirculation dysfunction and organ injury after ischemia and reperfusion (I/R) result from a complex pathologic process consisting of multiple links, with metabolism impairment in the ischemia phase and oxidative stress in the reperfusion phase as initiators, and any treatment targeting a single link is insufficient to cope with this. Compound Chinese medicine (CCM) has been applied in clinics in China and some Asian nations for more than 2000 years. Studies over the past decades revealed the protective and therapeutic effect of CCMs and major ingredients on I/R-induced microcirculatory dysfunction and tissue injury in the heart, brain, liver, intestine, and so on...
March 16, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28317886/systems-pharmacology-based-strategy-to-screen-new-adjuvant-for-hepatitis-b-vaccine-from-traditional-chinese-medicine-ophiocordyceps-sinensis
#4
Jingbo Wang, Rui Liu, Baoxiu Liu, Yan Yang, Jun Xie, Naishuo Zhu
Adjuvants are common component for many vaccines but there are still few licensed for human use due to low efficiency or side effects. The present work adopted Systems Pharmacology analysis as a new strategy to screen adjuvants from traditional Chinese medicine. Ophiocordyceps sinensis has been used for many years in China and other Asian countries with many biological properties, but the pharmacological mechanism has not been fully elucidated. First in this study, 190 putative targets for 17 active compounds in Ophiocordyceps sinensis were retrieved and a systems pharmacology-based approach was applied to provide new insights into the pharmacological actions of the drug...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28315856/an-update-on-hla-alleles-associated-with-adverse-drug-reactions
#5
Ingrid Fricke-Galindo, Adrián LLerena, Marisol López-López
Adverse drug reactions (ADRs) are considered as an important cause of morbidity and mortality. The hypersensitivity reactions are immune-mediated ADRs, which are dose-independent, unpredictable and have been associated with several HLA alleles. The present review aimed to describe HLA alleles that have been associated with different ADRs in populations worldwide, the recommendations of regulatory agencies and pharmacoeconomic information and databases for the study of HLA alleles in pharmacogenetics. A systematic search was performed in June 2016 of articles relevant to this issue in indexed journals and in scientific databases (PubMed and PharmGKB)...
March 18, 2017: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/28315022/report-of-the-89th-annual-scientific-meeting-of-the-japan-society-of-ultrasonics-in-medicine-the-12th-congress-of-the-asian-federation-of-societies-for-ultrasound-in-medicine-and-biology-and-the-8th-asian-conference-on-ultrasound-contrast-imaging-ultrasonic
#6
https://www.readbyqxmd.com/read/28303072/achievements-and-future-directions-of-the-apfcb-mass-spectrometry-harmonisation-project-on-serum-testosterone
#7
REVIEW
Ronda F Greaves, Chung S Ho, Kirsten E Hoad, John Joseph, Brett McWhinney, Janice P Gill, Therese Koal, Chris Fouracre, Heidi P Iu, Brian R Cooke, Conchita Boyder, Hai T Pham, Lisa M Jolly
As an outcome of the 2010 Asian Pacific Conference for Chromatography and Mass Spectrometry in Hong Kong, a collaborative working group was formed to promote the harmonisation of mass spectrometry methods. The Mass Spectrometry Harmonisation Working Group resides under the combined auspices of the Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB) and the Australasian Association of Clinical Biochemists (AACB). A decision was made to initially focus attention on serum steroids due to the common interest of members in this area; with the first steroid to assess being testosterone...
May 2016: Clinical Biochemist. Reviews
https://www.readbyqxmd.com/read/28302341/communication-behaviors-and-patient-autonomy-in-hospital-care-a-qualitative-study
#8
Zackary D Berger, Emily F Boss, Mary Catherine Beach
BACKGROUND: Little is known about how hospitalized patients share decisions with physicians. METHODS: We conducted an observational study of patient-doctor communication on an inpatient medicine service among 18 hospitalized patients and 9 physicians. A research assistant (RA) approached newly hospitalized patients and their physicians before morning rounds and obtained consent. The RA audio recorded morning rounds, and then separately interviewed both patient and physician...
March 7, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28299476/a-comparison-of-the-molecular-subtypes-of-triple-negative-breast-cancer-among-non-asian-and-taiwanese-women
#9
Ling-Ming Tseng, Jen-Hwey Chiu, Chun-Yu Liu, Yi-Fang Tsai, Yun-Lin Wang, Chu-Wen Yang, Yi-Ming Shyr
BACKGROUND: "Precision medicine" is a concept that by utilizing modern molecular diagnostics, an effective therapy is accurately applied for each cancer patient to improve their survival rates. The treatment of triple-negative breast cancer (TNBC) remains a challenging issue. The aim of this study was to compare the molecular subtypes of triple-negative breast cancer (TNBC) between Taiwanese and Non-Asian women. METHODS: GEO Datasets for non-Asian (12 groups, n = 1450) and Taiwanese (3 groups, n = 465) breast cancer, including 617 TNBC, were acquired, normalized and cluster analyzed...
March 15, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28295428/atheroprotective-effects-and-molecular-targets-of-tanshinones-derived-from-herbal-medicine-danshen
#10
REVIEW
Jian Fang, Peter J Little, Suowen Xu
Medicinal plant-derived bioactive compounds modulate multiple therapeutic targets in cardiovascular diseases (CVDs), rendering herb-derived phytochemicals effective against one of the major CVDs-atherosclerosis. Danshen (Salvia milthiorriza Bunge) is a Chinese medicine that has been used in cardio- and cerebro-vascular therapeutic remedies in Asian countries for many years. Emerging evidence from cellular, animal, and clinical studies suggests that major lipophilic tanshinones from Danshen can treat atherosclerotic CVDs...
February 16, 2017: Medicinal Research Reviews
https://www.readbyqxmd.com/read/28290319/consumer-perception-of-balsamic-vinegar-a-cross-cultural-study-between-korea-and-italy
#11
Luisa Torri, Seon-Young Jeon, Maria Piochi, Gabriella Morini, Kwang-Ok Kim
Understanding cross-cultural differences in food perception is a key issue of food research in order to understand consumer behaviour in different countries. The objective of this study was to explore potential cultural differences of balsamic vinegar perception between Korean and Italian consumers using the sorted napping method. Nine balsamic vinegars different in terms of ingredients, aging time, and origin were evaluated by Korean (n=50) and Italian (n=49) consumers using sorted napping. Familiarity and food matching were also examined...
January 2017: Food Research International
https://www.readbyqxmd.com/read/28280897/3d-photogrammetric-analysis-of-the-nasal-tip-projection-and-derotation-based-on-the-nasal-tip-quadripod-concept
#12
Jong Woo Choi, Young Chul Suh, Shin Young Song, Woo Shik Jeong
BACKGROUND: Regarding septal fixation in nasal tip plasty, the nasal tip tripod theory may require modification. We performed three-dimensional (3D) photogrammetric analysis of the "Skiff graft," which is a quadripod method involving folded conchal cartilages fixated on the caudal septal angle, paired lateral crura reinforced by a derotational conchal cartilage graft, and conjoined medial crus on the columella base. We assessed the efficacy of the Skiff graft in maintaining tip projection and preventing cephalic rotation of the nasal tip...
March 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28260011/ethyl-acetate-extract-from-asparagus%C3%A2-cochinchinensis-exerts-anti%C3%A2-inflammatory-effects-in-lps%C3%A2-stimulated-raw264-7-macrophage-cells-by-regulating-cox%C3%A2-2-inos-inflammatory-cytokine-expression-map-kinase-pathways-the-cell-cycle-and-anti-oxidant-activity
#13
Hyun Ah Lee, Eun Kyoung Koh, Ji Eun Sung, Ji Eun Kim, Sung Hwa Song, Dong Seob Kim, Hong Joo Son, Chung Yeoul Lee, Hee Seob Lee, Chang Joon Bae, Dae Youn Hwang
Asparagus cochinchinesis (A. cochinchinesis) is a medicine traditionally used to treat fever, cough, kidney disease, breast cancer, inflammatory disease and brain disease in northeast Asian countries. Although numerous studies of the anti‑inflammatory effects of A. cochinchinesis have been conducted, the underlying mechanisms of such effects in macrophages remain to be demonstrated. To investigate the mechanism of suppressive effects on the inflammatory response in macrophages, alterations of the nitric oxide (NO) level, the cell viability, inducible nitric oxide synthase (iNOS) and cyclooxygenase‑2 (COX‑2) expression levels, inflammatory cytokine expression, the mitogen-activated protein kinase (MAPK) signaling pathway, cell cycle arrest and reactive oxygen species (ROS) levels were measured in lipopolysaccharide (LPS)-activated RAW264...
April 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28259851/study-protocol-to-investigate-the-environmental-and-genetic-aetiology-of-atopic-dermatitis-the-indonesian-prospective-study-of-atopic-dermatitis-in-infants-isadi
#14
Conny Tanjung, Peter Rzehak, Muchtaruddin Mansyur, Zakiudin Munasir, Herawati Sudoyo, Suzanna Immanuel, Roedi Irawan, Eva Reischl, Hans Demmelmair, Berthold Koletzko, Sri Rezeki Hadinegoro, Damayanti Rusli Sjarif
INTRODUCTION: Atopic dermatitis (AD) is the most common skin disorder in young children worldwide, with a high impact on morbidity and quality of life. To date, no prospective study has been published on the incidence and potential predictors of AD in South East Asian populations. The Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI) will address the genetic, metabolic and dietary characteristics of mothers and their offspring, as well as potential determinants of AD within the first year of infant life...
March 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28258932/herbal-medicine-oreongsan-for-recurrent-chronic-subdural-hematoma-a-case-report
#15
Ki-Ho Cho, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon
Recently, the East-Asian herbal complex Oreongsan (Goreisan in Japanese and Wulingsan in Chinese) has been noted for its usefulness in preventing postoperative recurrence of chronic subdural hematoma (CSDH). Here, we present a case of CSDH, an 84-year-old man which had recurred four times, despite three previous burr-hole surgeries. Following the fourth burr-hole surgery, an herbal medicine called Oreongsan (TJ-17, Tsumura, Japan, 15g/d) was administered to the patient in hopes of preventing another CSDH recurrence...
December 18, 2016: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/28257063/red-yeast-rice
#16
Thu Nguyen, Mitchell Karl, Antonello Santini
Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for a long time in Asian cuisine and traditional medicine. It consists of multiple bioactive substances, including monacolins, which potentially can be used as a nutraceutical. Monacolin K, which is chemically identical to lovastatin, has been recognized as responsible for the cholesterolreducing effect of this compound. While the European Food Safety Authority maintains that the use of monacolin K from RYR preparations of at least 10 mg can produce a normal blood cholesterol level, the United States Food and Drug Administration considers monacolin K, due to its similarity with lovastatin, an unapproved drug, and therefore marketing of products that label the monacolin content is prohibited...
March 1, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28254482/lithospermum-erythrorhizon-extract-inhibits-der-p2-induced-inflammatory-response-through-alleviation-of-thymic-stromal-lymphopoietin-nuclear-factor-kappa-b-and-inflammasome-expression-in-human-bronchial-epithelial-cells
#17
Chung-Yang Yen, Wen-Dee Chiang, Shang-Yong Liu, Kun-Teng Wang, En-Chih Liao, Ching-Liang Hsieh
ETHNOPHARMACOLOGICAL RELEVANCE: Lithospermum erythrorhizon (LE) and Angelica sinensis (AS), widely used in several folk medicine for wound, pus discharge and dermatitis for the history of several hundred years in Asian countries. AIM OF STUDY: To investigate the therapeutic effect of LE and AS on Der p2-induced inflammatory response in human bronchial epithelial (BEAS-2B) cells. METHODS: The effects of Der p2 stimulation on thymic stromal lymphopoietin (TSLP), the nuclear factor kappa B (NF-κB) pathway, the inflammasome (specifically, the apoptosis speck-like protein [ASC] and nod-like receptor 3 [NLRP3]), Caspase-1 and the signal transducer and activator of transcription (STAT) 3 pathway were evaluated in the human bronchial epithelial (BEAS-2B) cells...
February 27, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28249821/ethno-veterinary-practices-in-southern-india-for-captive-asian-elephant-ailments
#18
Samidurai Jayakumar, Selvarasu Sathiskumar, Nagarajan Baskaran, Radjasegarin Arumugam, Varadhrajan Vanitha
ETHENOPHARMACOLOGICAL RELEVANCE: India has a long tradition of practicing Ayurvedic medicine not only for human ailments, but also for the management of livestock in the form of ethno-veterinary practices. Asian elephant is a significant part of Indian culture, and ethno-veterinary practices have extended to manage and cure various ailments of Asian elephant in captivity. Much of this knowledge has been lost in the light of modern practices. AIM OF THE STUDY: This study is aimed at documenting the existing knowledge on ethno-veterinary medicines practiced by elephant keepers (mahouts) in Tamil Nadu and Puducherry...
February 26, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28244320/hydrogel-based-materials-for-delivery-of-herbal-medicines
#19
Wing-Fu Lai, Andrey L Rogach
Herbal medicine, as an integral component of oriental medicine, has assimilated into the lives of Asian people for millennia. The therapeutic efficiency of herbal extracts and ingredients has, however, been limited by various factors, including the lack of targeting capacity and poor bioavailability. Hydrogels are hydrophilic polymer networks that can imbibe a substantial amount of fluids. Their high water content and low surface tension are some of the factors leading to good biocompatibility. Some hydrogels have also exhibited high drug loading efficiency, and have attracted widespread studies in pharmaceutical formulation...
February 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28220135/differential-gene-expression-analysis-in-polygonum-minus-leaf-upon-24-h-of-methyl-jasmonate-elicitation
#20
Reyhaneh Rahnamaie-Tajadod, Kok-Keong Loke, Hoe-Han Goh, Normah M Noor
Polygonum minus is an herbal plant that grows in Southeast Asian countries and traditionally used as medicine. This plant produces diverse secondary metabolites such as phenolic compounds and their derivatives, which are known to have roles in plant abiotic and biotic stress responses. Methyl jasmonate (MeJA) is a plant signaling molecule that triggers transcriptional reprogramming in secondary metabolism and activation of defense responses against many biotic and abiotic stresses. However, the effect of MeJA elicitation on the genome-wide expression profile in the leaf tissue of P...
2017: Frontiers in Plant Science
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