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https://www.readbyqxmd.com/read/28530408/authentication-markers-for-five-major-panax-species-developed-via-comparative-analysis-of-complete-chloroplast-genome-sequences
#1
Van Binh Nguyen, Hyun-Seung Park, Sang-Choon Lee, Junki Lee, Jee Young Park, Tae-Jin Yang
Ginseng represents a set of high-value medicinal plants of different species: Panax ginseng (Asian ginseng), P. quinquefolius (American ginseng), P. notoginseng (Chinese ginseng), P. japonicus (Bamboo ginseng), and P. vietnamensis (Vietnamese ginseng). Each species is pharmacologically and economically important, with differences in efficacy and price. Accordingly, an authentication system is needed to combat economically motivated adulteration of Panax products. We conducted comparative analysis of the chloroplast genome sequences of these five species, identifying 34-124 indels and 141-560 SNPs...
May 22, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28529298/an-aspect-of-the-history-of-medicine-in-ancient-korea-as-examined-through-silla-buddhist-monks-annotations-on-the-chapter-on-eliminating-disease-in-the-sutra-of-golden-light-suvarnabh%C3%A4-sa-s%C3%A5-tra
#2
Chaekun Oh, Jongwook Jeon, Dongwon Shin
Nearly nothing is known of medicine in ancient Korea due to insufficient materials. With several extant prescriptions and esoteric methods of treating diseases alone, it is impossible to gauge in depth the management of medicine during this period. If one exception were to be cited, that would be the fact that the annotations for understanding the contents on Indian medicine in the "Chapter on Eliminating Disease" in the Sutra of Golden Light, a Buddhist sutra originating from India, reflected the medical knowledge of Buddhist monks from Silla (57 BC-935 AD) who were active immediately after the nation's unification of the two other kingdoms on the Korean Peninsula (668 AD) such as Wonhyo (617-686 AD), Gyeongheung (620?-700? AD), and Seungjang (684-? AD)...
December 2016: Ŭi Sahak
https://www.readbyqxmd.com/read/28525904/prognostic-value-of-the-microrna-214-in-multiple-human-cancers-a-meta-analysis-of-observational-studies
#3
Yajing Feng, Fujiao Duan, Weigang Liu, Xiaoli Fu, Shuli Cui, Zhenxing Yang
Previous studies showed that microRNA-214 (miR-214) may act as a prognostic biomarker of cancer. However, the available evidence is controversial. This study summarizes evidence and evaluates the prognostic role of miR-214 in various cancers. We carried out a systematic literature review and assessed the quality of included studies based on Oxford Centre for Evidence-based Medicine Criteria and Newcastle-Ottawa Scale (NOS). Pooled hazard ratios (HRs) with corresponding 95% confidence intervals (CIs) for overall survival (OS) and disease free survival/progressive free survival/recurrence free survival (DFS/PFS/RFS) were calculated to measure the effective value of miR-214 expression on prognosis...
May 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28506903/ethnozoological-assessment-of-animals-used-by-mon-traditional-medicine-vendors-at-kyaiktiyo-myanmar
#4
Vincent Nijman, Chris R Shepherd
ETHNOPHARMACOLOGICAL RELEVANCE: Wild animals are widely used in traditional Asian medicine but information from Myanmar is lacking. We show that a wide range of animals are used at a pilgrimage site, mostly for their rendered fats and oils to be used in mixed concoctions. The majority of species were sold to be used to treat aching joints, muscle ache and skin diseases. AIM OF THE STUDY: To assess wildlife for sale for medicinal purposes, and document their medicinal use at Kyaiktiyo, a pilgrimage site at a 1100m tall mountain, with many of the pilgrims climbing to the top...
May 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28501008/ethanol-extract-and-its-dichloromethane-fraction-of-alpinia-oxyphylla-miquel-exhibited-hepatoprotective-effects-against-ccl4-induced-oxidative-damage-in-vitro-and-in-vivo-with-the-involvement-of-nrf2
#5
Qiao Zhang, Xiaolong Hu, Fuhai Hui, Qi Song, Can Cui, Changli Wang, Qingchun Zhao
Alpinia oxyphylla Miq. (A. oxyphylla), as a kind of medicine which also be used as food, is widely used in East Asian for the treatment of dyspepsia, diarrhea, abdominal pain and deficiency cold of spleen and stomach. This study aimed to investigate the protective effects of ethanol extract (EE) and its dichloromethane fraction (DM) of A. oxyphylla, which are rich in phenolic compounds, against CCl4-induced hepatic injury in vitro and in vivo. EE, DM and silymarin ameliorated CCl4-induced decrease of cell viability and increase of reactive oxygen species (ROS) in HepG2 cells...
May 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28499305/aristolic-acid-derivatives-from-the-bark-of-antidesma-ghaesembilla
#6
Sibylle Schäfer, Stefan Schwaiger, Hermann Stuppner
Antidesma ghaesembilla is an important medicinal and food plant in many Asian countries. Ten substances could be isolated from the dichloromethane and methanol extract: sitostenone (3), daucosterol (4), chavibetol (5), asperphenamate (6), protocatechuic acid (7), vanillic acid-4-O-β-D-glucoside (8), 1-O-β-D-glucopyranosyl-3-O-methyl-phloroglucinol (9), and aristolic acid II-8-O-β-D-glucoside (10), and two new aristolic acid derivatives, 10-amino-5,7-dimethoxy-aristolic acid II (= 6-amino-9,11-dimethoxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; 1) and 5,7-dimethoxy-aristolochic acid II (= 9,11-dimethoxy-6-nitrophenantro[3,4-d]-1,3-dioxole-5-carboxylic acid; 2)...
May 12, 2017: Planta Medica
https://www.readbyqxmd.com/read/28495603/ethnopharmacological-uses-phytochemistry-biological-activities-and-therapeutic-applications-of-clinacanthus-nutans-burm-f-lindau-a-comprehensive-review
#7
REVIEW
Muhamad Noor Alfarizal Kamarudin, Md Moklesur Rahman Sarker, Habsah Abdul Kadir, Long Chiau Ming
ETHNOPHARMACOLOGICAL RELEVANCE: Clinacanthus nutans (Burm. f.) Lindau, a widely used medicinal plant, is extensively grown in tropical Asia and Southeast Asian countries. C. nutans, with its broad spectrum of pharmacological activities, has been traditionally used to treat cancer, inflammatory disorders, diabetes, insect bites, and skin problems, consumed as a vegetable, mixed with fresh juices, in concoctions, and as a whole plant. The present review analyzes the advances in the ethnopharmacology, phytochemistry, pharmacology, and toxicology of C...
May 8, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28493115/cardiovascular-disease-cancer-risk-among-south-asians-impact-of-sociocultural-influences-on-lifestyle-and-behavior
#8
Namratha Kandula, Munerah Ahmed, Sunita Dodani, Leena Gupta, Paromita Hore, Alka Kanaya, Aijaz Khowaja, Ashish Mathur, Darshan Mehta, Ranjita Misra, Muhammad Paracha, Nazleen Bharmal, Mira Aghhi, Jennifer Leng, Francesca Gany
A comprehensive literature review revealed cultural beliefs, societal obligations, and gender roles within the South Asian community to be indirect contributors to the health of South Asian immigrants (SAIs). Health professionals need to increase their work with SAI communities to change less beneficial cultural elements such as misconceptions about health and exercise, and lack of communication when using alternative medicines. Community engaged efforts and continuing medical education are both needed to improve the health of the South Asian immigrant population in a culturally appropriate manner...
May 10, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28490237/phytochemistry-and-pharmacological-activities-of-the-genus-swertia-gentianaceae-a-review
#9
Jie Li, Yan-Li Zhao, Heng-Yu Huang, Yuan-Zhong Wang
Swertia plants have been considered to be medicinal plants useful for the treatment of various ailments for thousands of years, especially in Asian countries. This is due to the broad variety of chemical compounds that provide multiple ligands for bonding to different endogenous biomacromolecules for patients. Chemical constituents and pharmacological activities of Swertia plants are summarized in this paper. Approximately 419 metabolites and 40 bioactive compounds have been reported from 30 Swertia species, including xanthones, flavonoids, seco-iridiods, iridiods, triterpenoids, alkaloids, volatiles, and other secondary metabolites...
May 11, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28487653/chinese-herbal-medicines-attenuate-acute-pancreatitis-pharmacological-activities-and-mechanisms
#10
REVIEW
Hong Xiang, Qingkai Zhang, Bing Qi, Xufeng Tao, Shilin Xia, Huiyi Song, Jialin Qu, Dong Shang
Acute pancreatitis (AP) is a commonly occurring gastrointestinal disorder. An increase in the annual incidence of AP has been observed, and it causes acute hospitalization and high mortality. The diagnosis and treatment guidelines for AP recommend conservative medical treatments focused on reducing pancreatic secretion and secondary injury, as a primary therapeutic approach. Unfortunately, the existing treatment options have limited impact on the incidence and severity of AP due to the complex and multifaceted pathological process of this disease...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28486988/cerebrospinal-fluid-a%C3%AE-42-t-tau-and-p-tau-levels-in-the-differential-diagnosis-of-idiopathic-normal-pressure-hydrocephalus-a-systematic-review-and-meta-analysis
#11
REVIEW
Zhongyun Chen, Chunyan Liu, Jie Zhang, Norman Relkin, Yan Xing, Yanfeng Li
OBJECTIVES: The purpose of this systematic review and meta-analysis was to evaluate the performance of cerebrospinal fluid (CSF) beta amyloid 42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) as potential diagnostic biomarkers for idiopathic normal-pressure hydrocephalus (iNPH) and to assess their utility indistinguishing patients with iNPH from those with Alzheimer disease (AD) and healthy normal controls. METHODS: Studies were identified by searching PubMed, Embase, the Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Wanfang Chinese Periodical Database, VIP Chinese database, and Chinese Bio-medicine Database (CBM) before August 2016...
May 10, 2017: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/28486159/trends-of-thromboprophylaxis-and-complications-after-major-lower-limb-orthopaedic-surgeries-in-korea-national-health-insurance-claim-data
#12
Sunyoung Kim, Hongyup Ahn, Soon-Ae Shin, Jong-Heon Park, Chang Won Won
BACKGROUND: In Western countries, prophylaxis for venous thromboembolism (VTE) following major lower limb orthopaedic surgeries is recommended. However, that has not been the case in Asian countries, where the reported incidence of postoperative VTE has been low. The present study examined trends in VTE prophylaxis prescriptions and related complications following major lower limb orthopaedic surgeries in South Korea. DESIGN/PARTICIPANTS: Using claim data from the National Health Insurance Corporation, 263,664 patients aged 65years or older who underwent major orthopaedic surgeries (total hip arthroplasty [THA], total knee arthroplasty [TKA], or hip fracture surgery [HFS]) between 2008 and 2012 were included...
April 26, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28483828/sources-of-sodium-in-us-adults-from-3-geographic-regions
#13
Lisa J Harnack, Mary E Cogswell, James M Shikany, Christopher D Gardner, Cathleen Gillespie, Catherine M Loria, Xia Zhou, Keming Yuan, Lyn M Steffen
BACKGROUND: Most US adults consume excess sodium. Knowledge about the dietary sources of sodium intake is critical to the development of effective reduction strategies. METHODS: A total of 450 adults were recruited from 3 geographic locations: Birmingham, AL (n=150); Palo Alto, CA (n=150); and the Minneapolis-St. Paul, MN (n=150), metropolitan areas. Equal numbers of women and men from each of 4 race/ethnic groups (blacks, Asians, Hispanics, and non-Hispanic whites) were targeted for recruitment...
May 9, 2017: Circulation
https://www.readbyqxmd.com/read/28476158/melicope-ptelefolia-leaf-extracts-exhibit-antioxidant-activity-and-exert-anti-proliferative-effect-with-apoptosis-induction-on-four-different-cancer-cell-lines
#14
Mohammad Faujul Kabir, Johari Mohd Ali, Mitra Abolmaesoomi, Onn Haji Hashim
BACKGROUND: Melicope ptelefolia is a well-known herb in a number of Asian countries. It is often used as vegetable salad and traditional medicine to address various ailments. However, not many studies have been currently done to evaluate the medicinal benefits of M. ptelefolia (MP). The present study reports antioxidant, anti-proliferative, and apoptosis induction activities of MP leaf extracts. METHOD: Young MP leaves were dried, powdered and extracted sequentially using hexane (HX), ethyl acetate (EA), methanol (MeOH) and water (W)...
May 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28462130/water-extract-of-galla-rhois-with-steaming-process-enhances-apoptotic-cell-death-in-human-colon-cancer-cells
#15
Nam-Hui Yim, Min Jung Gu, Youn-Hwan Hwang, Won-Kyung Cho, Jin Yeul Ma
BACKGROUND: Galla Rhois has been considered to have medicinal properties against diarrhea, excessive sweating, bleeding, and chronic cough in Asian countries. Gallotannins, which are Galla Rhois-derived tannins, have been reported to possess biological and pharmacological activities, especially anticancer activity. In this study, we evaluated the effect of steaming at a temperature over 120 °C on the chemical constituents and biological activities of the water extract of Galla Rhois (GRE)...
December 2016: Integr Med Res
https://www.readbyqxmd.com/read/28461125/modulation-of-neurogenesis-via-neurotrophic-factors-in-acupuncture-treatments-for-neurological-diseases
#16
REVIEW
Hwa Kyoung Shin, Sae-Won Lee, Byung Tae Choi
Acupuncture is one of the main healing arts in Oriental medicine. It has long been used in East Asian countries, including Korea and China, and is thought to be an effective alternative treatment for various neurological diseases. The therapeutic effects of acupuncture come from inserting a needle at specific acupoints on the body surface, with subsequent delivery of stimulation via manual rotation or electric pulses (electroacupuncture, EA). In various neurological disease models, peripheral nerve stimulation using acupuncture or EA may have protective effects on neural tissues by increasing expression of neurotrophic factors (NTFs), such as brain-derived neurotrophic factor and glial-derived neurotrophic factor, in the central nervous system, especially the brain...
April 29, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28458333/emphasizing-humanities-in-medical-education-promoting-the-integration-of-medical-scientific-spirit-and-medical-humanistic-spirit
#17
Peipei Song, Wei Tang
In the era of the biological-psychological-social medicine model, an ideal of modern medicine is to enhance the humanities in medical education, to foster medical talents with humanistic spirit, and to promote the integration of scientific spirit and humanistic spirit in medicine. Throughout the United States (US), United Kingdom (UK), other Western countries, and some Asian countries like Japan, many medical universities have already integrated the learning of medical humanities in their curricula and recognized their value...
April 29, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/28454586/n-hexane-intoxication-in-a-chinese-medicine-pharmaceutical-plant-a-case-report
#18
Jo-Hui Pan, Chiung-Yu Peng, Chung-Ting Lo, Chia-Yen Dai, Chao-Ling Wang, Hung-Yi Chuang
BACKGROUND: n-Hexane is a well-known neurotoxicant. Polyneuropathy due to occupational n-hexane exposure has been reported worldwide, however, our case is the first report in the Chinese herb industry. CASE PRESENTATION: A 25-year-old Asian man experienced progressive weakness and numbness in his hands and feet after working as an operator in a Chinese medicine pharmaceutical plant for the manufacture of Chinese herbal pain relief patches for 10 months. Electrophysiological studies indicated a reduction in nerve conduction velocity, prolongation of distal latencies, mildly positive sharp waves, and reduced recruitment with polyphasic potentials, particularly at distal sites...
April 28, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28451799/micro-autologous-fat-transplantation-maft-for-forehead-volumizing-and-contouring
#19
C K Chou, S S Lee, T Y Lin, Y H Huang, H Takahashi, C S Lai, S D Lin, T M Lin
BACKGROUND: Frontal fullness in Asians is often considered to indicate one's public popularity and leadership skills. Numerous materials and techniques have been applied clinically to recontour or volumize the frontal area, with variable results. The micro-autologous fat transplantation (MAFT) technique proposed by Lin et al. (2nd academic congress of Taiwan Cosmetic Association Taipei, Taiwan) in 2007 has demonstrated its feasibility in facial rejuvenation. In the present study, we used an innovative instrument to apply the MAFT technique to frontal augmentation with fat grafting and reported the results...
April 27, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28445955/metformin-is-associated-with-survival-benefit-in-pancreatic-cancer-patients-with-diabetes-a-systematic-review-and-meta-analysis
#20
Ping-Ting Zhou, Bo Li, Fu-Rao Liu, Mei-Chao Zhang, Qian Wang, Yan-Yan Li, Ci Xu, Yuan-Hua Liu, Yuan Yao, Dong Li
BACKGROUND: Pancreatic cancer is a highly lethal disease with a poor prognosis while metformin has been associated with a decreased risk of pancreatic cancer. Although the benefit of metformin was observed for pancreatic cancer prevention, it is not clear whether it can also affect the survival of pancreatic cancer patients with type 2 diabetes mellitus. A systematic review and meta-analysis was conducted to assess the effect of metformin on the survival of pancreatic cancer patients with type 2 diabetes mellitus...
April 11, 2017: Oncotarget
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