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https://www.readbyqxmd.com/read/29928915/renal-failure-and-active-tuberculosis-in-a-high-incidence-uk-city
#1
E Moran, J Baharani, M Dedicoat, E Robinson, G Smith, P Bhomra, O S Thien, R Ryan
OBJECTIVES: The risk of developing active TB is greater in those receiving haemodialysis. This study aimed to describe the incidence of active tuberculosis among patients referred for management of kidney disease and dialysis in a high incidence UK city, with the purpose of informing latent TB testing and treatment practice. METHODS: Information from the tuberculosis register was cross-referenced with the Department of Renal Medicine patient information system. All patients seen between 1st January 2005 and 1st October 2016 were included in the analyses with the exception of those with prior TB...
June 18, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29924497/cyp2e1-rsa-%C3%AE-pst-%C3%AE-polymorphism-and-lung-cancer-susceptibility-a-meta-analysis-involving-10-947-subjects
#2
Ze-Tian Shen, Xin-Hu Wu, Bing Li, Jun-Shu Shen, Zhen Wang, Jing Li, Xi-Xu Zhu
The above article, published in the Journal of Cellular and Molecular Medicine on 14 September 2016 in Wiley Online Library (wileyonlinelibrary.com), and in Volume 19, pp. 2136-2142, has been retracted by agreement between the authors, the journal Editor in Chief, Stefan Constantinescu, and John Wiley & Sons Ltd. The retraction has been agreed due to unattributed overlap of the language used in the "Materials and method" and "Discussion" sections of this study and the following article published in Lung Cancer: "CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians" by Ping Zhan, Jing Wang, Yu Zhang, Li-Xin Qiu, Su-feng Zhao, Qian Qian, Shu-Zhen Wei, Li-Ke Yu and Yong Song, Volume 69, 2010, pages 19-25...
July 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29913255/chemoprevention-of-leishmaniasis-in-vitro-antiparasitic-activity-of-dibenzalacetone-a-synthetic-curcumin-analog-leads-to-apoptotic-cell-death-in-leishmania-donovani
#3
Indira Singh Chauhan, G SubbaRao, Jai Shankar, Lalit Kumar Singh Chauhan, Govind J Kapadia, Neeloo Singh
Curcumin is the major phenolic compound found in turmeric, a dry powder of rhizomes and roots of the plant, Curcuma longa L., which is widely used as spice and food colorant around the world, and in herbal medicinal practice in Asian countries. The present study reports the leishmanicidal activity of trans-dibenzalacetone (DBA), a synthetic monoketone analog of curcumin, against Leishmania donovani parasites. We for the first time report the antiproliferative effect of a curcumin analog (DBA) on the intracellular amastigotes of L...
June 15, 2018: Parasitology International
https://www.readbyqxmd.com/read/29908314/quality-control-of-goji-fruits-of-lycium-barbarum-l-and-l-chinense-mill-a-value-chain-analysis-perspective
#4
Ruyu Yao, Michael Heinrich, Zigui Wang, Caroline S Weckerle
ETHNOPHARMACOLOGICAL RELEVANCE: Goji (fruits of Lycium barbarum L. and L. chinense Mill., Solanaceae) have been used as a traditional food and medicine for hundreds of years in Asian countries and are now consumed globally. Quality of herbal medicines is critical for safe use and has been shown to be affected by value chains. AIM OF THE STUDY: Using a value chain (VC) framework, we aim at understanding the influence of different VC types on goji quality and revenue of stakeholders...
June 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29907221/racial-ethnic-disparities-in-the-adjuvant-chemotherapy-of-locally-advanced-colon-cancer-patients
#5
Xi Zhong, Zhexu Guo, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Yu Sun, Zhenning Wang
BACKGROUND: Most race/ethnicity-oriented investigations focus on Caucasian Americans (whites) and African Americans (blacks), leaving Asians, Hispanic white (Hispanics), and other minorities less well studied. Adjuvant chemotherapy (CT) after curative resection is critical to patients with locally advanced colon cancer (LACC). We studied the racial disparities in the adjuvant CT of LACC to aid in selecting optimal treatments for people from different races/ethnicities in this era of precision medicine...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29895962/the-antiviral-drug-arbidol-inhibits-zika-virus
#6
Susan L Fink, Lucia Vojtech, Jessica Wagoner, Natalie S J Slivinski, Konner J Jackson, Ruofan Wang, Sudip Khadka, Priya Luthra, Christopher F Basler, Stephen J Polyak
There are many emerging and re-emerging globally prevalent viruses for which there are no licensed vaccines or antiviral medicines. Arbidol (ARB, umifenovir), used clinically for decades in several countries as an anti-influenza virus drug, inhibits many other viruses. In the current study, we show that ARB inhibits six different isolates of Zika virus (ZIKV), including African and Asian lineage viruses in multiple cell lines and primary human vaginal and cervical epithelial cells. ARB protects against ZIKV-induced cytopathic effects...
June 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29887604/-i-don-t-want-to-be-henrietta-lacks-diverse-patient-perspectives-on-donating-biospecimens-for-precision-medicine-research
#7
Sandra S-J Lee, Mildred K Cho, Stephanie A Kraft, Nina Varsava, Katie Gillespie, Kelly E Ormond, Benjamin S Wilfond, David Magnus
PURPOSE: To determine whether patients distinguish between biospecimens and electronic health records (EHRs) when considering research participation to inform research protections. METHODS: We conducted 20 focus groups with individuals who identified as African American, Hispanic, Chinese, South Asian, and non-Hispanic white on the collection of biospecimens and EHR data for research. RESULTS: Our study found that many participants did not distinguish between biospecimens and EHR data...
June 11, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29881686/plastome-wide-comparison-reveals-new-snv-resources-for-the-authentication-of-dendrobium-huoshanense-and-its-corresponding-medicinal-slice-huoshan-fengdou
#8
Zhitao Niu, Jiajia Pan, Qingyun Xue, Shuying Zhu, Wei Liu, Xiaoyu Ding
Dendrobium species and their corresponding medicinal slices have been extensively used as traditional Chinese medicine (TCM) in many Asian countries. However, it is extremely difficult to identify Dendrobium species based on their morphological and chemical features. In this study, the plastomes of D. huoshanense were used as a model system to investigate the hypothesis that plastomic mutational hotspot regions could provide a useful single nucleotide variants (SNVs) resource for authentication studies. We surveyed the plastomes of 17 Dendrobium species, including the newly sequenced plastome of D...
May 2018: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/29881684/synergistic-immunoreaction-of-acupuncture-like-dissolving-microneedles-containing-thymopentin-at-acupoints-in-immune-suppressed-rats
#9
Qian Zhang, Chuncao Xu, Shiqi Lin, Huanbin Zhou, Gangtao Yao, Hu Liu, Lili Wang, Xin Pan, Guilan Quan, Chuanbin Wu
Dissolving microneedles carried drug molecules can effectively penetrate the stratum corneum of skin to improve the transdermal drug delivery. The traditional Chinese medicine acupuncture is based on the needle stimulation at a specific location (acupoint) to generate and transmit biochemical and physiological signals which alter the pathophysiological state of patients. However, the pain associated with conventional acupuncture needles and the requirement of highly trained professionals limit the development of acupuncture in non-Asian countries...
May 2018: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/29880082/possible-antithrombotic-effects-of-angelica-keiskei-ashitaba
#10
N Ohkura, G Atsumi, K Ohnishi, K Baba, M Taniguchi
Angelica keiskei Koidzumi (Ashitaba) is a large perennial herb that is native to the Pacific coast of Japan, and it has recently become popular as herbal medicine, dietary supplement and health food in Asian countries. The structures of various constituents isolated from Ashitaba such as chalcones, flavanones and coumarins have been precisely characterized, and many of them have bioactivities. A recent study clarified that Angelica keiskei exerts actions that lead to the prevention of thrombosis. Here, we introduce the possibility that ingesting Ashitaba could help to prevent thrombotic diseases...
June 1, 2018: Die Pharmazie
https://www.readbyqxmd.com/read/29872510/b-glucans-from-grifola-frondosa-and-ganoderma-lucidum-in-breast-cancer-an-example-of-complementary-and-integrative-medicine
#11
REVIEW
Paola Rossi, Raffaele Difrancia, Vincenzo Quagliariello, Elena Savino, Paolo Tralongo, Cinzia Lucia Randazzo, Massimiliano Berretta
Culinary and medicinal mushrooms are widely used in Asian countries, both as dietary supplements and as nutraceutical foods. They have recently become popular in Europe, as well, for their nutritional and health benefits. In particular, epidemiological studies conducted in Asia suggest that mushroom intake, together with other phytotherapy substances, protects against cancer, specifically gastrointestinal (GI) and breast cancers. Most of the data come from in vitro studies and in vivo experimental animal models...
May 15, 2018: Oncotarget
https://www.readbyqxmd.com/read/29867486/contamination-parts-and-residue-levels-of-multi-mycotoxins-in-medicinal-and-edible-locust
#12
Dandan Kong, Weijun Kong, Xiaoli Yang, Meihua Yang
Locust is esteemed as a traditional Chinese medicine, as well as one of the most important nutritional foods especially in Asian countries. However, some toxic secondary metabolites such as mycotoxins are usually found in different parts of locust to affect its quality and safety. This study aimed to investigate the aflatoxins (AFs) contaminated parts by observing Aspergillus flavus , spores' diameter, amount and distribution on head, tentacle, wing, belly and shank parts of the locust with scanning electron microscopy (SEM)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29843642/gestational-weight-gain-in-chinese-women-results-from-a-retrospective-cohort-in-changsha-china
#13
Xin Huang, Hongzhuan Tan, Ming Cai, Ting Shi, Chunmei Mi, Jun Lei
BACKGROUND: The generalizability of the gestational weight gain (GWG) ranges recommended by the Institute of Medicine (IOM) to Chinese women is disputed. METHODS: In 2016, 16,780 pregnant women who gave birth to live singletons in Changsha, China, were enrolled. First, subjects with optimal pregnancy outcomes were identified for the GWG percentile distribution description and for comparison to the IOM recommendations. Second, all subjects with optimal GWG according to the IOM body mass index (BMI) cutoffs and those with optimal GWG according to the Asian BMI cutoffs were selected...
May 29, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29806618/assessment-of-physicians-proficiency-in-reading-chest-radiographs-for-pneumoconiosis-based-on-a-60-film-examination-set-with-two-factors-constituting-eight-indices
#14
Taro Tamura, Yukinori Kusaka, Narufumi Suganuma, Kazuhiro Suzuki, Ponglada Subhannachart, Somkiat Siriruttanapruk, Narongpon Dumavibhat, Xing Zhang, P K Sishodiya, Tran Anh Thanh, Kurt G Hering, John E Parker, Eduardo Algranti, Francisco Santos-O'Connor, Hisao Shida, Masanori Akira
Two hundred and thirty-three individuals read chest x-ray images (CXR) in the Asian Intensive Reader of Pneumoconiosis (AIR Pneumo) workshop. Their proficiency in reading CXR for pneumoconiosis was calculated using eight indices (X1-X8), as follows: sensitivity (X1) and specificity (X2) for pneumoconiosis; sensitivity (X3) and specificity (X4) for large opacities; sensitivity (X5) and specificity (X6) for pleural plaques; profusion increment consistency (X7); and consistency for shape differentiation (X8). For these eight indices, one-way analysis of variance (ANOVA) and Scheffe's multiple comparison were conducted on six groups, based on the participants' specialty: radiology, respiratory medicine, industrial medicine, public health, general internal medicine, and miscellaneous physicians...
May 26, 2018: Industrial Health
https://www.readbyqxmd.com/read/29796604/travel-related-risk-factors-for-coccidioidomycosis
#15
James H Diaz
Background: Coccidioidomycosis is a regionally endemic systemic mycosis with unique risk factors. Since people travel for business or pleasure, and often in conjunction with their avocations or hobbies, the objectives of this review were to describe these and other risk factors for coccidioidomycosis; to alert travel medicine clinicians to the different presenting manifestations of coccidioidomycosis; and to recommend effective treatment, disease control and prevention strategies. Methods: To meet the objectives of this review, Internet search engines were queried with the keywords as medical subject headings over the study period, 1970-2017...
January 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29794403/bst106-protects-against-cartilage-damage-by-inhibition-of-apoptosis-and-enhancement-of-autophagy-in-osteoarthritic-rats
#16
Jeong-Min Hong, Jun-Kyu Shin, Jeom-Yong Kim, Min-Jung Jang, Sun-Kyu Park, Jong-Hoon Lee, Jung-Hyo Choi, Sun-Mee Lee
Chrysanthemum zawadskii var. latilobum (CZ) has been used as a traditional medicine in Asian countries for the treatment of inflammatory diseases. Recently, CZ extract was shown to inhibit differentiation of osteoclasts and provide protection against rheumatoid arthritis. The aim of this study was to investigate the molecular mechanisms of BST106, the ethanol extract of CZ, for cartilage protection in monosodium iodoacetate (MIA)-induced osteoarthritis (OA), particularly focusing on apoptosis and autophagy...
May 23, 2018: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29791813/higher-lung-cancer-incidence-in-young-women-than-young-men-in-the-united-states
#17
Ahmedin Jemal, Kimberly D Miller, Jiemin Ma, Rebecca L Siegel, Stacey A Fedewa, Farhad Islami, Susan S Devesa, Michael J Thun
BACKGROUND: Previous studies showed a higher incidence of lung cancer among young women than among young men in the United States. Whether this pattern has continued in contemporary birth cohorts and, if so, whether it can be fully explained by sex differences in smoking behaviors are unknown. METHODS: We examined the nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group (30 to 34, 35 to 39, 40 to 44, 45 to 49, and 50 to 54 years), year of birth (1945 to 1980), and calendar period of diagnosis (1995-1999, 2000-2004, 2005-2009, and 2010-2014), and we calculated female-to-male incidence rate ratios...
May 24, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29790361/anti-bacterial-effects-of-components-from-sanguisorba-officinalis-l-on-vibrio-vulnificus-and-their-soluble-epoxide-hydrolase-inhibitory-activity
#18
Xiang Dong Su, Rui Hong Guo, Seo Young Yang, Young Ho Kim, Young Ran Kim
Sanguisorba officinalis L. is a traditional herbal medicine, which is prevailingly applied to cure hemorrhoids, wounds and ulcers in Eastern Asian countries. The purpose of this study was to investigate the antibacterial and soluble epoxide hydrolase (sEH) inhibitory effects of the extracts and components from S. officinalis. The methanol extract was divided into ethyl acetate (EtOAc), n-butanol (n-BuOH), and water layers. In our screening procedure, the EtOAc and n-BuOH extracts and compounds (1-2) remarkably suppressed the growth of V...
May 23, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29789303/-me_who-anatomy-of-scholastic-leadership-and-social-isolation-of-underrepresented-minority-women-in-academic-medicine
#19
Michelle A Albert
In academic medicine, under-represented minority women physician-scientists (URMWP)* are uncommon, particularly in leadership positions. Data from the American Association of Medical Colleges (AAMC) show that among internal medicine chairs, there are 12 Asian males, 10 African/American (blacks; 9 men), 7 Hispanics (2 females) and 137 whites (21 females). In the top 40 ranked cardiology programs, there are no female cardiology chiefs, whereas there are at least 10, 2, 1 and 24 Asian, black, Hispanic and white males respectively...
May 22, 2018: Circulation
https://www.readbyqxmd.com/read/29788885/application-of-traditional-chinese-herbal-medicine-by-products-as-dietary-feed-supplements-and-antibiotic-replacements-in-animal-production
#20
Abedin Abdallah, Pei Zhang, Qingzhen Zhong, Zewei Sun
Misuse of synthetic antibiotics in livestock leads to the transfer of antibiotic resistant pathogens into humans and deposits toxic residues in meat and milk. There is therefore an urgent need for safe and viable alternative approaches to improve the nutrition and wellbeing of farm animals. An alternative source that has been widely exploited is traditional Chinese herbal medicine (TCHM). These herbal medicines are an important part of the healthcare system in many Asian countries. Such herbs contain several but less toxic bioactive compounds which are generally regarded biodegradable...
May 22, 2018: Current Drug Metabolism
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