James E Kragel, Youssef Ezzyat, Michael R Sperling, Richard Gorniak, Gregory A Worrell, Brent M Berry, Cory Inman, Jui-Jui Lin, Kathryn A Davis, Sandhitsu R Das, Joel M Stein, Barbara C Jobst, Kareem A Zaghloul, Sameer A Sheth, Daniel S Rizzuto, Michael J Kahana
Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in humans. Encoding and retrieval are supported by the engagement of both distinct neural pathways across the cortex and common structures within the medial temporal lobes. However, the degree to which memory performance can be determined by neural processing that is common to encoding and retrieval remains to be determined. To identify neural signatures of successful memory function, we administered a delayed free-recall task to 187 neurosurgical patients implanted with subdural or intraparenchymal depth electrodes...
July 15, 2017: NeuroImage