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https://www.readbyqxmd.com/read/28549338/fast-backprojection-based-reconstruction-of-spectral-spatial-epr-images-from-projections-with-the-constant-sweep-of-a-magnetic-field
#1
Denis A Komarov, Hiroshi Hirata
In this paper, we introduce a procedure for the reconstruction of spectral-spatial EPR images using projections acquired with the constant sweep of a magnetic field. The application of a constant field-sweep and a predetermined data sampling rate simplifies the requirements for EPR imaging instrumentation and facilitates the backprojection-based reconstruction of spectral-spatial images. The proposed approach was applied to the reconstruction of a four-dimensional numerical phantom and to actual spectral-spatial EPR measurements...
May 17, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28549293/automated-recognition-of-the-pericardium-contour-on-processed-ct-images-using-genetic-algorithms
#2
É O Rodrigues, L O Rodrigues, L S N Oliveira, A Conci, P Liatsis
This work proposes the use of Genetic Algorithms (GA) in tracing and recognizing the pericardium contour of the human heart using Computed Tomography (CT) images. We assume that each slice of the pericardium can be modelled by an ellipse, the parameters of which need to be optimally determined. An optimal ellipse would be one that closely follows the pericardium contour and, consequently, separates appropriately the epicardial and mediastinal fats of the human heart. Tracing and automatically identifying the pericardium contour aids in medical diagnosis...
May 17, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28549292/globally-supported-radial-basis-function-based-collocation-method-for-evolution-of-level-set-in-mass-segmentation-using-mammograms
#3
Kanchan Lata Kashyap, Manish Kumar Bajpai, Pritee Khanna
Computer-aided detection systems play an important role for the detection of breast abnormalities using mammograms. Global segmentation of mass in mammograms is a complex process due to low contrast mammogram images, irregular shape of mass, speculated margins, and the presence of intensity variations of pixels. This work presents a new approach for mass detection in mammograms, which is based on the variational level set function. Mesh-free based radial basis function (RBF) collocation approach is employed for the evolution of level set function for segmentation of breast as well as suspicious mass region...
May 15, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28549207/morphological-descriptors-and-issr-molecular-markers-in-the-evaluation-of-genetic-variability-of-tectona-grandis-genotypes
#4
A M Chimello, J G Jesus, P E Teodoro, A A B Rossi, K L Araújo, T N Marostega, L G Neves, M A A Barelli
This study aimed to evaluate the genetic variability of the teak germplasm bank, using morphological traits and inter-simple sequence repeat molecular markers. Thirty clones were evaluated in a randomized complete block design with three replicates, and each plot was composed of three plants. A joint analysis of quantitative and qualitative variables was performed using the Gower algorithm. Quantitative, qualitative, and molecular variables were analyzed simultaneously using the Ward-MLM procedure. There is genetic variability among the 30 teak genotypes studied, considering the quantitative, qualitative, and molecular variables by the Ward-MLM statistical procedure...
May 25, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28549168/assessing-the-thermal-dissipation-sap-flux-density-method-for-monitoring-cold-season-water-transport-in-seasonally-snow-covered-forests
#5
Allison M Chan, David R Bowling
Productivity of conifers in seasonally snow-covered forests is high before and during snowmelt when environmental conditions are optimal for photosynthesis. Climate change is altering the timing of spring in many locations, and changes in the date of transition from winter dormancy can have large impacts on annual productivity. Sap flow methods provide a promising approach to monitor tree activity during the cold season and the winter-spring and fall-winter transitions. Although sap flow techniques have been widely used, cold season results are generally not reported...
May 26, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28548676/the-diagnosis-and-management-of-chronic-migraine-in-primary-care
#6
Werner J Becker
BACKGROUND: Chronic migraine is common, affecting approximately 1% of the general population, and causes significant disability. OBJECTIVE: To summarize optimal involvement of primary care physicians in chronic migraine care, and to provide algorithms to assist them in the diagnosis and management of patients with chronic migraine. METHODS: An analysis of diagnostic and treatment needs in chronic migraine, based on a synthesis of the medical literature and clinical experience...
May 26, 2017: Headache
https://www.readbyqxmd.com/read/28548650/aflibercept-in-age-related-macular-degeneration-evaluating-its-role-as-a-primary-therapeutic-option
#7
REVIEW
M Ashraf, A A R Souka
The recent VIEW studies have demonstrated the non-inferiority of monthly and bi-monthly aflibercept in the management of wet age related macular degeneration (AMD) compared with ranibizumab. However, the current data are limited mainly to fixed dosing regimens with few studies looking at flexible dosing regimens of aflibercept in wet AMD. In addition, recent data from the VIEW 96 week extension has shown that patients being shifted from fixed dosing regimens to PRN have shown a drop in visual acuity and increase in central macular thickness...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28548536/inductive-supervised-quantum-learning
#8
Alex Monràs, Gael Sentís, Peter Wittek
In supervised learning, an inductive learning algorithm extracts general rules from observed training instances, then the rules are applied to test instances. We show that this splitting of training and application arises naturally, in the classical setting, from a simple independence requirement with a physical interpretation of being nonsignaling. Thus, two seemingly different definitions of inductive learning happen to coincide. This follows from the properties of classical information that break down in the quantum setup...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548299/a-noninvasive-diagnosis-of-hepatic-fibrosis-by-biofibroscore%C3%A2-in-chronic-hepatitis-c-patients
#9
Chen-Hua Liu, Chun-Jen Liu, Chun-Ming Hong, Tung-Hung Su, Hung-Chih Yang, Kuei-Ming Chen, Yi-Ping Huang, Yu-Ming Yeh, Hui-Lan Tien, Yuan-Chih Liu, Jia-Horng Kao, Ding-Shinn Chen, Pei-Jer Chen
BACKGROUND & AIMS: The diagnostic accuracy of a novel serological panel (BioFibroScore®) to predict hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection is unknown. METHODS: Three markers of BioFibroScore®, including urokinase plasminogen activator (uPA), matrix metalloproteinase-9 (MMP-9), and beta-2 microglobulin (β2M), were retrospectively evaluated in 635 HCV-infected patients who received percutaneous liver biopsy and FibroScan®. The formula of BioFibroScore® to predict the severity of hepatic fibrosis was developed by Adaboost algorithm...
May 26, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28548044/falcon-a-highly-flexible-open-source-software-for-closed-loop-neuroscience
#10
Davide Ciliberti, Fabian Kloosterman
OBJECTIVE: Closed-loop experiments provide unique insights into brain dynamics and function. Here, we demonstrate an open-source software platform that enables high-performance real-time processing of streaming experimental data, suitable for a wide range of closed-loop experiments. APPROACH: We wrote a C++ multi-threaded software (Falcon) in which the user can load and execute an arbitrary processing graph. Each node in the graph is internally mapped to a single thread and nodes communicate with each other through thread-safe buffers...
May 26, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28547868/improving-three-dimensional-mechanical-imaging-of-breast-lesions-with-principal-component-analysis
#11
Mohit Tyagi, Yuqi Wang, Timothy Hall, Paul E Barbone, Assad A Oberai
PURPOSE: Elastography has emerged as a new tool for detecting and diagnosing many types of diseases including breast cancer. To date, most clinical applications of elastography have utilized two-dimensional strain images. The goal of this paper is to present a new quasi-static elastography technique that yields shear modulus images in three dimensions METHODS: An automated breast volume scanner was used to acquire ultrasound images of the breast as it was gently compressed. Cross-correlation between successive images was used to determine the displacement within the tissue...
May 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28547809/treatment-of-lumbar-spinal-stenosis-by-microscopic-unilateral-laminectomy-for-bilateral-decompression-a-technical-note
#12
Kevin Phan, Ian Teng, Konrad Schultz, Ralph J Mobbs
Lumbar spinal stenosis is typically a degenerative condition that leads to compression of the spinal canal and lateral recess, resulting in leg pain and walking disability. Surgical management is indicated after failure of non-surgical management or rapidly worsening neurological impairment. The traditional approach is a laminectomy with foraminotomy and partial facetectomy but a newer minimally invasive option, unilateral laminectomy for bilateral decompression (ULBD), seems to demonstrate the better postoperative outcomes due to its unilateral exposure...
May 26, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28547755/demographic-and-socioeconomic-influences-on-helicobacter-pylori-gastritis-and-its-pre-neoplastic-lesions-amongst-us-residents
#13
R M Genta, K O Turner, A Sonnenberg
BACKGROUND: Gastric infection with Helicobacter pylori (Hp) can lead to chronic inactive gastritis, atrophy and intestinal metaplasia. AIMS: To investigate in a cross-sectional study these changes among different socioeconomic and ethnic groups within the USA. METHODS: We used the Miraca Life Sciences database, an electronic depository of clinicopathological records from patients distributed throughout the USA, to extract data from 487 587 patients who underwent oesophago-gastro-duodenoscopy with biopsy between 1/2008 and 12/2014...
May 25, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28547747/deciphering-common-recognition-principles-of-nucleoside-mono-di-and-tri-phosphates-binding-in-diverse-proteins-via-structural-matching-of-their-binding-sites
#14
Raghu Bhagavat, Narayanaswamy Srinivasan, Nagasuma Chandra
Nucleoside triphosphate (NTP) ligands are of high biological importance and essential for all life forms. A pre-requisite for them to participate in diverse biochemical processes is their recognition by diverse proteins. It is thus of great interest to understand the basis for such recognition in different proteins. Towards this, we have employed a structural bioinformatics approach and analyse structures of 4677 NTP complexes available in PDB. Binding sites were extracted and compared exhaustively by using PocketMatch, a sensitive in-house site comparison algorithm, which resulted in grouping the entire dataset into 27 site-types...
May 25, 2017: Proteins
https://www.readbyqxmd.com/read/28547116/groove-binding-of-vanillin-and-ethyl-vanillin-to-calf-thymus-dna
#15
Kaixin Xia, Guowen Zhang, Song Li, Deming Gong
Vanillin (VAN) and ethyl vanillin (EVA) are widely used food additives as flavor enhancers, but may have a potential security risk. In this study, the properties of binding of VAN or EVA with calf thymus DNA (ctDNA) were characterized by multi-spectroscopic methods, multivariate curve resolution-alternating least-squares (MCR-ALS) algorithm and molecular simulation. The concentration profiles for the components (VAN or EVA, ctDNA and VAN-ctDNA or EVA-ctDNA complex) by the MCR-ALS analysis showed that VAN or EVA interacted with ctDNA and formed VAN-ctDNA or EVA-ctDNA complex...
May 25, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28547006/on-homotopy-continuation-for-speech-restoration
#16
Darian M Onchis, Pedro Real
In this paper, a homotopy-based method is employed for the recovery of speech recordings from missing or corrupted samples taken in a noisy environment. The model for the acquisition device is a compressed sensing scenario using Gabor frames. To recover an approximation of the speech file, we used the basis pursuit denoising method with the homotopy continuation algorithm. We tested the proposed method with various speech recordings.
June 2, 2016: Comput Topol Image Context (2016)
https://www.readbyqxmd.com/read/28546992/identification-of-transcription-factors-potentially-involved-in-human-adipogenesis-in%C3%A2-vitro
#17
Melvin Anyasi Ambele, Michael Sean Pepper
BACKGROUND: Increased adiposity in humans leads to obesity, which is a major risk factor for cardiovascular disease, type 2 diabetes, and cancer. We previously conducted an extensive unbiased in vitro transcriptomic analysis of adipogenesis, using human adipose-derived stromal cells (ASCs). Here, we have applied computational methods to these data to identify transcription factors (TFs) that constitute the upstream gene regulatory networks potentially, driving adipocyte formation in human ASCs...
May 2017: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/28546904/a-fast-image-simulation-algorithm-for-scanning-transmission-electron-microscopy
#18
Colin Ophus
Image simulation for scanning transmission electron microscopy at atomic resolution for samples with realistic dimensions can require very large computation times using existing simulation algorithms. We present a new algorithm named PRISM that combines features of the two most commonly used algorithms, namely the Bloch wave and multislice methods. PRISM uses a Fourier interpolation factor f that has typical values of 4-20 for atomic resolution simulations. We show that in many cases PRISM can provide a speedup that scales with f(4) compared to multislice simulations, with a negligible loss of accuracy...
2017: Advanced Structural and Chemical Imaging
https://www.readbyqxmd.com/read/28546863/ecg-signal-analysis-using-modified-s-transform
#19
Birendra Biswal
Accurate detection of QRS complexes is essential for the investigation of heart rate variability. Several transform techniques have been proposed and extensively used for the detection and analysis of QRS complexes. In this proposed work, the de-noised ECG signal is subjected to a modified S-transform for QRS complex detection.The performance analysis of the proposed work is evaluated using parameters such as sensitivity, positive predictivity and accuracy. The algorithm delivers sensitivity, positive predictivity and overall accuracy of 99...
April 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28546808/improving-classification-performance-through-an-advanced-ensemble-based-heterogeneous-extreme-learning-machines
#20
Adnan O M Abuassba, Dezheng Zhang, Xiong Luo, Ahmad Shaheryar, Hazrat Ali
Extreme Learning Machine (ELM) is a fast-learning algorithm for a single-hidden layer feedforward neural network (SLFN). It often has good generalization performance. However, there are chances that it might overfit the training data due to having more hidden nodes than needed. To address the generalization performance, we use a heterogeneous ensemble approach. We propose an Advanced ELM Ensemble (AELME) for classification, which includes Regularized-ELM, L2-norm-optimized ELM (ELML2), and Kernel-ELM. The ensemble is constructed by training a randomly chosen ELM classifier on a subset of training data selected through random resampling...
2017: Computational Intelligence and Neuroscience
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