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Coronary Artery Calcium

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https://www.readbyqxmd.com/read/29667200/treatment-in-a-preventive-cardiology-clinic-utilizing-advanced-practice-providers-apps-effectively-closes-atherosclerotic-cardiovascular-disease-ascvd-risk-management-gaps-amongst-a-primary-prevention-population-compared-with-a-propensity-matched-primary-care
#1
Emilio Fentanes, Anthony G Vande Hei, R Scott Holuby, Norma Suarez, Yousif Slim, Jennifer N Slim, Ahmad M Slim, Dustin Thomas
BACKGROUND: Advanced Practice Providers (APPs) can fill access to care gaps created by physician shortages and improve adherence/compliance with preventive atherosclerotic cardiovascular disease (ASCVD) interventions. METHODS: We retrospectively reviewed data on 595 patients enrolled in a preventive cardiology clinic (PCC) utilizing APPs compared with a propensity-matched cohort (PMC) of 595 patients enrolled in primary care clinics alone. PCC patients were risk stratified using Framingham risk scoring (FRS) and coronary artery calcium scoring (CACS) and treated based on published guideline-based algorithms...
April 17, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29664030/do-practice-gaps-exist-in-evidence-based-medication-prescription-at-hospital-discharge-in-patients-undergoing-coronary-artery-bypass-surgery-coronary-angioplasty
#2
Pradeep Pereira, Aditya Kapoor, Archana Sinha, Surendra K Agarwal, Shantanu Pande, Roopali Khanna, Nilesh Srivastava, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin Goel
Background & objectives: Prescription patterns of guideline-directed medical therapy (GDMT) after coronary artery bypass surgery [coronary artery bypass graft (CABG)] and percutaneous coronary intervention (PCI) at hospital discharge are often not optimal. In view of scarce data from the developing world, a retrospective analysis of medication advice to patients following CABG and PCI was conducted. Methods: Records of 5948 patients (post-PCI: 5152, post-CABG: 796) who underwent revascularization from 2010 to 2014 at a single tertiary care centre in north India were analyzed...
December 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29663283/eeg-artifact-versus-subclinical-status-epilepticus-in-a-patient-following-cardiac-arrest
#3
Jean E Cibula, Daniel S Demos, Brenda G Fahy
BACKGROUND: A challenge in ICU EEG interpretation is identifying subclinical status epilepticus versus patterns on the ictal-interictal continuum versus other repetitive patterns. In the electrically noisy intensive care unit, identifying and eliminating interference and artifact allow accurate diagnoses from the EEG, avoiding unnecessary treatment or sedation. METHODS: We present a case during Impella (Abiomed Inc, Danvers, MA) continuous flow left ventricular assist device use where the EEG artifact was initially misinterpreted as seizure by the resident and treated as status epilepticus because of the "focal" sharply contoured repetitive pattern...
April 16, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29663177/intravascular-ultrasound-assessment-of-the-effects-of-rotational-atherectomy-in-calcified-coronary-artery-lesions
#4
Sung Sik Kim, Myong Hwa Yamamoto, Akiko Maehara, Novalia Sidik, Kohei Koyama, Colin Berry, Keith G Oldroyd, Gary S Mintz, Margaret McEntegart
We sought to clarify intravascular ultrasound (IVUS) features of rotational atherectomy (RA) of calcified lesions. IVUS was performed post-RA and post-stent in 38 lesions and analyzed every 1 mm. Pre-intervention IVUS was performed when the IVUS catheter crossed the lesion (n = 11). Calcium Index was average calcium angle multiplied by calcium length. We compared lowest (n = 13), middle (n = 13), and highest (n = 12) Calcium Index tertiles. Reverberations (multiple reflections from calcium) with a concave-shaped lumen in the post-RA IVUS were considered to represent RA-related calcium modification...
April 16, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29659778/impact-of-diabetes-mellitus-on-the-contractile-properties-of-the-left-and-right-atrial-myofilaments
#5
Constanze Bening, Khaled Alhussini, Elena-Aura Mazalu, Jonathan Yaqub, Khaled Hamouda, Dejan Radakovic, Christoph Schimmer, Grzegorz Hirnle, Rainer Leyh
OBJECTIVES: The incidence of diabetes mellitus in patients with ischaemic cardiomyopathy is increasing. To evaluate the impact of diabetes mellitus on contractility, we examined the calcium-induced force in left and right atrial myofilaments of patients with and without diabetes. METHODS: We included 149 patients (106 without diabetes, 43 with diabetes), scheduled for elective coronary artery bypass grafting from August 2016 to June 2017. The left and right atria were excised and prepared for skinned fibre measurements (pCa-force curve)...
April 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29655684/protective-role-and-mechanism-of-snakegourd-peel-against-myocardial-infarction-in-rats
#6
Guanlin Yang, Dongyu Min, Junwei Yan, Ming Yang, Guijun Lin
BACKGROUND: Injection of snakegourd peel (SP), an herb used in traditional Chinese medicine, is used to treat coronary artery disease and stable angina in China. However, its therapeutic role and mechanism of action for the treatment of myocardial infarction (MI) is not fully understood. PURPOSE: The present study was designed to investigate the effect of SP on MI-induced cardiac injury and elucidate its underlying molecular mechanisms. METHODS: To create an in vivo model of MI, we ligated the left coronary artery of Wistar rats...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29625564/urinary-proteomics-for-prediction-of-mortality-in-patients-with-type-2-diabetes-and-microalbuminuria
#7
Gemma E Currie, Bernt Johan von Scholten, Sheon Mary, Jose-Luis Flores Guerrero, Morten Lindhardt, Henrik Reinhard, Peter K Jacobsen, William Mullen, Hans-Henrik Parving, Harald Mischak, Peter Rossing, Christian Delles
BACKGROUND: The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of mortality and cardiovascular disease in patients with microalbuminuria (MA) is unknown. METHODS: Urine samples were obtained from 155 patients with type 2 diabetes and confirmed microalbuminuria. Proteomic analysis was undertaken using capillary electrophoresis coupled to mass spectrometry to determine the CKD273 classifier score...
April 6, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29622976/patients-with-non-obstructive-coronary-artery-disease-admitted-with-acute-myocardial-infarction-carry-a-better-outcome-compared-to-those-with-obstructive-coronary-artery-disease
#8
Yasser Yazied Abdelmonem, Adel Abdelgawad Bakr, Hossam Ghanem El-Hossary, Mohammed Mahmoud Abdel Ghany
Background: The characterization of patients who have acute myocardial infarction (AMI) and insignificant coronary stenosis is unclear. Aim: The present study aimed to investigate the clinical profile, in-hospital and 3-month outcome of AMI patients with insignificant coronary stenosis in comparison with those with significant disease. Methods: This prospective observational study included 200 consecutive patients admitted with AMI. Group I (100 patients) included patients with insignificant CAD (all lesions <50% stenosis)...
September 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622969/relationship-between-serum-osteoprotegerin-and-vascular-calcifications-in-hemodialysis-patients
#9
Tarek Z El Baz, Osama A Khamis, Amal El-Shehaby, Hussein Chahine, Ahmad Alaa Al-Din Ahmed, Mostafa A Alsawasany
Background: Uremia is a vasculopathic process, and both cardiac calcification and vascular calcification seen from the early stages of chronic kidney disease. Osteoprotegerin could play a crucial role in atherosclerotic plaque formation, maturation and calcification. The goal of this study was to determine the relationship of serum osteoprotegerin with vascular calcification in patients with end stage kidney disease who were maintained on regular hemodialysis. Methods: Sixty clinically stable chronic renal failure patients undergoing regular hemodialysis were enrolled in this cross sectional study...
June 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29611835/essential-role-for-smooth-muscle-cell-stromal-interaction-molecule-1-in-myocardial-infarction
#10
Vishal Mali, Samuel Haddox, Souad Belmadani, Khalid Matrougui
OBJECTIVES: Stromal interacting molecule-1 (STIM1) plays a role in coordinating calcium signaling in different cell types. The increase or deletion of STIM1 expression in cardiomyocyte causes cardiac complication. Moreover, the deletion of STIM1 in endothelial cell causes vascular endothelial dysfunction. However, the disruption of STIM1 in smooth muscle cells (SMC) has no effect on endothelial function but protects vascular function when mice are infused with angiotensin-II. Nevertheless, the role of SMC-STIM1 in acute and chronic myocardial infarction (MI) induced by acute ischemia-reperfusion injury and permanent coronary artery occlusion is unknown...
February 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29610608/pharmacotherapy-evaluation-and-utilization-in-coronary-artery-bypass-grafting-patients-in-kosovo-during-the-period-2016-2017
#11
Armond Daci, Adnan Bozalija, Raif Cavolli, Rame Alaj, Giangiacomo Beretta, Shaip Krasniqi
BACKGROUND: Coronary Artery Bypass Grafting (CABG) is realised in patients with critical or advanced disease of coronary arteries. There are different pharmacotherapeutic approaches which are used as management, treatment and preventive therapy in cardiovascular disease or related comorbidities. Performing a successful surgery, pharmacotherapy, and increase of bypass patency rate remains a serious challenge. AIM: This study aims to analyse the patient characteristics undergoing CABG and evaluation of their drug utilisation rate and daily dosages in the perioperative period...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29609131/hepatocyte-growth-factor-is-associated-with-progression-of-atherosclerosis-the-multi-ethnic-study-of-atherosclerosis-mesa
#12
Elizabeth J Bell, Paul A Decker, Michael Y Tsai, James S Pankow, Naomi Q Hanson, Christina L Wassel, Nicholas B Larson, Kevin P Cohoon, Matthew J Budoff, Joseph F Polak, James H Stein, Suzette J Bielinski
BACKGROUND AND AIMS: Hepatocyte growth factor (HGF) has previously been associated with risk of stroke, coronary heart disease, and atherosclerosis. We hypothesized that higher circulating HGF is associated with greater progression of measures of atherosclerosis: coronary artery calcium (CAC) and carotid plaque. METHODS: Participants aged 45-84 years from the prospective cohort study Multi-Ethnic Study of Atherosclerosis had HGF measured at baseline (between 2000 and 2002) and were followed for progression of atherosclerosis for up to 12 years...
March 23, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29607444/oct-based-three-dimensional-modeling-of-stent-deployment
#13
Pengfei Dong, David Prabhu, David L Wilson, Hiram G Bezerra, Linxia Gu
Stent deployment has been widely used to treat narrowed coronary artery. Its acute outcome in terms of stent under expansion and malapposition depends on the extent and shape of calcifications. However, no clear understanding as to how to quantify or categorize the impact of calcification. We have conducted ex vivo stenting characterized by the optical coherence tomography (OCT). The goal of this work is to capture the ex vivo stent deployment and quantify the effect of calcium morphology on the stenting. A three dimensional model of calcified plaque was reconstructed from ex vivo OCT images...
November 2017: International Mechanical Engineering Congress and Exposition: [proceedings]
https://www.readbyqxmd.com/read/29600583/compositional-analysis-of-coronary-artery-calcification-in-dialysis-patients-in-vivo-by-dual-energy-computed-tomography-angiography
#14
Yoko Nishizawa, Chieko Higuchi, Takashi Nakaoka, Hisako Omori, Tetsuya Ogawa, Hiroshi Sakura, Kosaku Nitta
While vascular calcification is an important factor regulating prognosis in dialysis patients, its components have not been adequately studied. We analyzed in vivo components of calcification in the coronary arteries of dialysis patients using the effective atomic number from dual-energy computed tomography. In dialysis patients (hemodialysis, N = 10; peritoneal dialysis, N = 12), average of median effective atomic number was 13.8 in the hemodialysis group, and 13.7 in the peritoneal dialysis group...
March 30, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29597077/urine-cotinine-level-with-smoking-history-predicts-a-risk-of-coronary-artery-calcification
#15
Hui-Jin Yu, Sangeun Lim, Min-Kyeong Kim, Seungjun Lee, Min-Jung Kwon, Hyosoon Park, Hee-Yeon Woo
We investigated whether urine cotinine level, alone or combined with smoking status and cumulative smoking amount, could predict coronary calcium (CAC) score increase over time. The study population included 10,980 subjects. We analysed an association between CAC score increase over time and single or combined smoking-related factors. Urine cotinine level of ≥100 ng/mL, current or ex-smokers, and cumulative smoking amount of ≥1 pack-years (PY) showed significantly higher odds ratios (ORs) for CAC score increase over time...
March 21, 2018: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29593281/long-term-effects-of-low-calcium-dialysates-on-the-serum-calcium-levels-during-maintenance-hemodialysis-treatments-a-systematic-review-and-meta-analysis
#16
Masahiro Yoshikawa, Osamu Takase, Taro Tsujimura, Etsuko Sano, Matsuhiko Hayashi, Tsuyoshi Takato, Keiichi Hishikawa
Hypercalcemia and hyperparathyroidism in patients receiving maintenance hemodialysis (MHD) can cause the progression of cardiovascular diseases (CVD) and mineral bone disorders (MBD). The KDIGO recommends the dialysates with a calcium (Ca) concentration of 1.25-1.5 mmol/L for MHD treatments, but the optimal concentration remains controversial. Here, we conducted a systematic review and a meta-analysis of seven randomized controlled trials examining a total of 622 patients to investigate the optimal concentration for MHD for 6 months or longer...
March 28, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29590353/percutaneous-aspiration-of-calcium-debris-resulting-in-coronary-artery-occlusion-after-aortic-valve-replacement
#17
Martin Simek, Martin Sluka, Marek Gwozdziewicz
No abstract text is available yet for this article.
March 26, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29590332/subclinical-coronary-artery-disease-in-swiss-hiv-positive-and-hiv-negative-persons
#18
Philip E Tarr, Bruno Ledergerber, Alexandra Calmy, Thanh Doco-Lecompte, Alex Marzel, Rainer Weber, Philipp A Kaufmann, René Nkoulou, Ronny R Buechel, Helen Kovari
Aims: HIV-positive persons have increased cardiovascular event rates but data on the prevalence of subclinical atherosclerosis compared with HIV-negative persons are not uniform. We assessed subclinical atherosclerosis utilizing coronary artery calcium (CAC) scoring and coronary computed tomography angiography (CCTA) in 428 HIV-positive participants of the Swiss HIV Cohort Study and 276 HIV-negative controls concurrently referred for clinically indicated CCTA. Methods and results: We assessed the association of HIV infection, cardiovascular risk profile, and HIV-related factors with subclinical atherosclerosis in univariable and multivariable analyses...
March 24, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29589390/high-brachial-ankle-pulse-wave-velocity-as-a-marker-for-predicting-coronary-artery-stenosis-in-patients-with-type-2-diabetes
#19
Bo Hyun Kim, Jae Sik Jang, Yong Seop Kwon, June Hyung Kim, In Joo Kim, Chang Won Lee
BACKGROUND: We evaluated the ability of brachial ankle pulse wave velocity (baPWV) to predict coronary artery stenosis (CAS) in patients with type 2 diabetes, and compared the predictive power of baPWV to that of well-known cardiovascular disease (CVD) risk calculators. METHODS: The study group included 83 consecutive patients over 30 years old with type 2 diabetes who complained of vague chest discomfort. An automatic pulse waveform analyzer was used to measure baPWV...
March 2018: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29579601/circulating-interleukin-6-is-a-biomarker-for-coronary-atherosclerosis-in-nonalcoholic-fatty-liver-disease-results-from-the-multi-ethnic-study-of-atherosclerosis
#20
Tracey G Simon, Maria Esther Perez Trejo, Robyn McClelland, Ryan Bradley, Michael J Blaha, Irfan Zeb, Kathleen E Corey, Matthew J Budoff, Raymond T Chung
BACKGROUND: Biomarkers to predict the presence and severity of subclinical cardiovascular disease (CVD) in nonalcoholic fatty liver disease (NAFLD) are lacking. METHODS: 3876 participants from the Multi-Ethnic Study of Atherosclerosis (MESA), without known chronic liver disease underwent baseline non-contrast cardiac CT, with NAFLD defined by validated liver:spleen ratio (L:S) < 1.0, and subclinical CVD defined by coronary artery calcium (CAC) score > 0...
May 15, 2018: International Journal of Cardiology
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