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https://www.readbyqxmd.com/read/29457844/effect-of-type-d-personality-on-smoking-status-and-their-combined-impact-on-outcome-after-acute-myocardial-infarction
#1
Egidio Imbalzano, Marco Vatrano, Sebastiano Quartuccio, Roberto Ceravolo, Vincenzo Antonio Ciconte, Paola Rotella, Renato Pardeo, Giovanni Trapani, Pasquale De Fazio, Cristina Segura-Garcia, Rossella Costantino, Antonino Saitta, Giuseppe Mandraffino
BACKGROUND: Smoking cessation is correlated with several psychological, social, biological, and pharmacological aspects. The combined tendency to experience negative emotions and to inhibit the expression of these emotions is indicated as "type D personality," an independent risk marker for clinical outcome in cardiac disease. Despite this effect of type D personality on cardiovascular disease, it is still unclear whether this personality trait may influence smoking cessation after a myocardial infarction...
February 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29457713/probing-structural-changes-among-analogous-inhibitor-bound-forms-of-hiv-1-protease-and-a-drug-resistant-mutant-in-solution-by-nuclear-magnetic-resonance
#2
Shahid N Khan, John D Persons, Janet L Paulsen, Michel Guerrero, Celia A Schiffer, Nese Kurt-Yilmaz, Rieko Ishima
In the era of state-of-the-art inhibitor design and high-resolution structural studies, detection of significant but small protein structural differences in the inhibitor-bound forms is critical to further developing the inhibitor. Here, we probed differences in HIV-1 protease (PR) conformation among darunavir and four analogous inhibitor-bound forms and compared them with a drug-resistant mutant using nuclear magnetic resonance chemical shifts. Changes in amide chemical shifts of wild-type (WT) PR among these inhibitor-bound forms, ΔCSP, were subtle but detectable and extended >10 Å from the inhibitor-binding site, asymmetrically between the two subunits of PR...
February 19, 2018: Biochemistry
https://www.readbyqxmd.com/read/29457582/green-leafy-and-cruciferous-vegetable-consumption-and-risk-of-type-2-diabetes-results-from-the-singapore-chinese-health-study-and-meta-analysis
#3
Guo-Chong Chen, Woon-Puay Koh, Jian-Min Yuan, Li-Qiang Qin, Rob M van Dam
Several previous prospective studies suggest that consumption of green leafy and cruciferous vegetables may lower the risk of type 2 diabetes (T2D). We investigated the association between consumption of different types of vegetables in relation to T2D risk in an Asian Population. We included 45 411 participants (age range: 45-74 years) of the Singapore Chinese Health Study (SCHS) free of diabetes, cancer or CVD at baseline (1993-1998). Dietary information was collected using a validated FFQ. Physician-diagnosed incident diabetes was reported at follow-up I (1999-2004) and II (2006-2010) interviews...
February 19, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29457520/caregiver-reactions-to-aggressive-behaviors-in-persons-with-dementia-in-a-diverse-community-dwelling-sample
#4
Bryan R Hansen, Nancy A Hodgson, Chakra Budhathoki, Laura N Gitlin
PURPOSE: To describe caregiver challenges with and confidence managing three aggressive behavior types in persons with dementia: verbal aggression, destroying property, and threatening to hurt others. DESIGN AND METHOD: Secondary analysis of baseline data from the 2001-2004 Resources for Enhancing Alzheimer's Caregiver Health II (REACH II) initiative. RESULTS: One or more aggressive behaviors within 1 week were reported by more than a third of caregivers, with most expressing upset but fewer expressing confidence managing the behaviors...
February 1, 2018: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/29457488/referral-patterns-and-implementation-costs-of-the-partners-in-recovery-initiative-in-gippsland-learnings-for-the-national-disability-insurance-scheme
#5
Anton N Isaacs, Kim Dalziel, Keith Sutton, Darryl Maybery
OBJECTIVE: The purpose of this paper is to provide some learnings for the NDIS from the referral pattern and cost of implementing the Partners in Recovery initiative of Gippsland. METHOD: Information on referral areas made for each consumer was collated from support facilitators. Cost estimates were determined using budget estimates, administrative costs and a literature review and are reported from a government perspective. RESULTS: Sixty-three per cent of all referrals were made to organisations that provided multiple types of services...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29456422/understanding-the-meaning-of-food-in-people-with-type-2-diabetes-living-in-northern-appalachia
#6
Elizabeth A Beverly, Marilyn D Ritholz, Linda A Wray, Ching-Ju Chiu, Emmy Suhl
Purpose: Food and eating convey memories and feelings and serve important functions in creating and maintaining relationships. Given the increasing rate of diabetes in the United States, research understanding the meaning of food may shed light on how patients negotiate everyday food choices while managing type 2 diabetes. The purpose of this qualitative study was to explore the meaning of food among adults with type 2 diabetes living in Northern Appalachia. Methods: In-depth, face-to-face interviews were conducted with type 2 diabetes patients...
February 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29456150/antidepressants-as-antipruritic-agents-a-review
#7
REVIEW
Randeep Kaur, V R Sinha
Pruritus is a concomitant symptom of various underlying disorders viz. dermatological, systemic and psychiatric disorders that provoke the person to scratch the skin. Many natural as well as, antipruritic therapies are usually practiced in the treatment of pruritus including general preventive measures, topical therapies such as cooling agents, antihistamines, anesthetics, capsaicin, corticosteroids, immunomodulators and; systemic therapies including administration of antihistamines, opioid antagonists/agonists, antiepileptic drugs/neuroleptics (e...
February 15, 2018: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29456091/frequency-of-human-papillomavirus-infection-in-patients-with-gastrointestinal-cancer
#8
F Roesch-Dietlen, A D Cano-Contreras, Y J Sánchez-Maza, J M Espinosa-González, M Á Vázquez-Prieto, E J Valdés-de la O, F Díaz-Roesch, M Á Carrasco-Arroniz, A Cruz-Palacios, P Grube-Pagola, A Sumoza-Toledo, H Vivanco-Cid, G Mellado-Sánchez, A Meixueiro-Daza, C S Silva-Cañetas, M G Carrillo-Toledo, R Lagunes-Torres, M Amieva-Balmori, P C Gómez-Castaño, J U Reyes-Huerta, J M Remes-Troche
INTRODUCTION AND AIM: Cancer is the result of the interaction of genetic and environmental factors. It has recently been related to viral infections, one of which is human papillomavirus. The aim of the present study was to describe the frequency of human papillomavirus infection in patients with digestive system cancers. MATERIALS AND METHODS: A prospective, multicenter, observational study was conducted on patients with gastrointestinal cancer at 2public healthcare institutes in Veracruz...
February 15, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29455697/meaningful-ways-of-understanding-and-measuring-change-for-people-with-borderline-personality-disorder-a-thematic-analysis
#9
Louise McCusker, Marie-Louise Turner, Georgina Pike, Helen Startup
BACKGROUND: The effective treatment of Borderline Personality Disorder (BPD) presents healthcare providers with a significant challenge. The evidence base remains limited partially due to a lack of professional consensus and service user involvement regarding ways of measuring change. As a result, the limited evidence that is available draws on such a wide range of outcome measures, that comparison across treatment types is hindered, maintaining a lack of clarity regarding the clinical needs of this group...
February 19, 2018: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/29455383/healthcare-experiences-of-low-income-women-with-prior-gestational-diabetes
#10
Reena Oza-Frank, Elizabeth Conrey, Jo Bouchard, Cynthia Shellhaas, Mary Beth Weber
Introduction An important yet understudied component of postpartum type 2 diabetes risk reduction among high risk women is experiences with the healthcare system. Our objective was to describe the healthcare experiences of a diverse, low-income sample of women with prior GDM, including their suggestions for improving care. Methods Focus groups were conducted among African American, Hispanic, and Appalachian women who were diagnosed with GDM within the past 10 years. Participants were recruited from community and medical resources...
February 17, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29454824/candida-albicans-biology-molecular-characterization-pathogenicity-and-advances-in-diagnosis-and-control-an-update
#11
REVIEW
Maryam Dadar, Ruchi Tiwari, Kumaragurubaran Karthik, Sandip Chakraborty, Youcef Shahali, Kuldeep Dhama
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an important source of invasive disease in humans and generating high healthcare costs worldwide. This fungus is frequently found in different anatomical sites of healthy persons and could induce systemic and superficial infections under optimal environmental conditions. Invasive candidiasis (IC) is an important nosocomial infection with high morbidity and mortality rates in hospitalized children. It represents a major source of prolonged infections in intensive care unit (ICU), particularly in immunosuppressed or elderly patients...
February 15, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29454243/health-inequities-faced-by-ethiopian-migrant-domestic-workers-in-lebanon
#12
Bina Fernandez
This paper investigates the healthcare needs, access to healthcare, and healthcare strategies of Ethiopian migrant domestic workers (MDWs) in Lebanon, drawing on qualitative empirical research. The analysis focusses on four types of health care needs: minor illnesses, pregnancies, serious illnesses (such as cancer, tuberculosis or heart problems), and emergencies (due to accidents, suicide attempts or assaults). Predictably, access to healthcare is distinctly differentiated according to an MDW's status as a documented, freelancer, or undocumented worker...
February 14, 2018: Health & Place
https://www.readbyqxmd.com/read/29454016/mother-and-child-personality-traits-associated-with-common-feeding-strategies-and-child-body-mass-index
#13
Angelina R Sutin, Antonio Terracciano
The feeding strategies that parents use with their children shape their children's attitudes and behaviors toward food. The present research examined whether personality traits of the mother and the child are associated with the types of feeding strategies mothers use with their children. The present research also examined whether these characteristics are associated with the child's body mass index (BMI). Mothers (N = 2928) reported how often they used three feeding strategies (Restriction, Pressure to Eat, Monitoring) with the target child and their personality and the personality of the child...
February 14, 2018: Appetite
https://www.readbyqxmd.com/read/29453308/sex-specific-mechanisms-of-resistance-vessel-endothelial-dysfunction-induced-by-cardiometabolic-risk-factors
#14
Ana P Davel, Qing Lu, M Elizabeth Moss, Sitara Rao, Imran J Anwar, Jennifer J DuPont, Iris Z Jaffe
BACKGROUND: The incidence of obesity is rising, particularly among women. Microvascular dysfunction is more common with female sex, obesity, and hyperlipidemia and predicts adverse cardiovascular outcomes, but the molecular mechanisms are unclear. Because obesity is associated with mineralocorticoid receptor (MR) activation, we tested the hypothesis that MR in endothelial cells contribute to sex differences in resistance vessel dysfunction in response to cardiometabolic risk factors. METHODS AND RESULTS: Male and female endothelial cell-specific MR knockout mice and MR-intact littermates were randomized to high-fat-diet-induced obesity or obesity with hyperlipidemia induced by adeno-associated virus-based vector targeting transfer of the mutant stable form (DY mutation) of the human PCSK9 (proprotein convertase subtilisin/kexin type 9) gene and compared with control diet...
February 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29453156/approaching-the-experience-of-people-through-the-process-of-a-colostomy
#15
Raquel Palomero-Rubio, Azucena Pedraz-Marcos, Ana María Palmar-Santos
OBJECTIVE: The purpose of this paper is to explore the experience of people who go through the process of a colostomy. METHOD: Methodological approach of qualitative type and with a phenomenological framework, through in-depth interviews. Six women and 12 men, between 38 and 86 years of age, were interviewed before and after surgery, between 3 and 6 months after the intervention. The discourses were recorded and transcribed verbatim and analyzed following the 3 stages of Taylor and Bogdan: finding in progress, data coding and refinement of the understanding of the subject of study, and relativisation of the findings...
February 13, 2018: Enfermería Clínica
https://www.readbyqxmd.com/read/29453008/forensic-image-analysis-cctv-distortion-and-artefacts
#16
REVIEW
Dilan Seckiner, Xanthé Mallett, Claude Roux, Didier Meuwly, Philip Maynard
As a result of the worldwide deployment of surveillance cameras, authorities have gained a powerful tool that captures footage of activities of people in public areas. Surveillance cameras allow continuous monitoring of the area and allow footage to be obtained for later use, if a criminal or other act of interest occurs. Following this, a forensic practitioner, or expert witness can be required to analyse the footage of the Person of Interest. The examination ultimately aims at evaluating the strength of evidence at source and activity levels...
February 6, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29452453/-personalized-ophthalmology-induced-pluripotent-stem-cells-for-in-vitro-modelling-of-retinal-degenerative-diseases
#17
Caroline Brandl, Bernhard H F Weber
Today, the search for therapeutic options to treat retinal degeneration often relies on an in-depth understanding of the underlying pathological events. Alternatively, it is conceivable to search, in an undirected screening approach, for chemical compounds affecting disease outcome. For both approaches, there is an urgent need for in vitro and, ideally, in vivo disease models that adequately reflect the site of pathology. Currently available animal models possess limitations as they often develop only defined aspects of disease...
February 16, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29452422/asynchronous-and-pathological-windows-of-implantation-two-causes-of-recurrent-implantation-failure
#18
P Sebastian-Leon, N Garrido, J Remohí, A Pellicer, P Diaz-Gimeno
STUDY QUESTION: Is endometrial recurrent implantation failure (RIF) only a matter of an asynchronous (displaced) window of implantation (WOI), or could it also be a pathological (disrupted) WOI? SUMMARY ANSWER: Our predictive results demonstrate that both displaced and disrupted WOIs exist and can present independently or together in the same RIF patient. WHAT IS KNOWN ALREADY: Since 2002, many gene expression signatures associated with endometrial receptivity and RIF have been described...
February 14, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29452366/prevalence-and-incidence-of-anal-and-cervical-high-risk-human-papillomavirus-hpv-types-covered-by-current-hpv-vaccines-among-hiv-infected-women-in-the-study-to-understand-the-natural-history-of-hiv-aids-in-the-era-of-effective-therapy-the-sun-study
#19
Erna Milunka Kojic, Lois Conley, Tim Bush, Susan Cu-Uvin, Elizabeth R Unger, Keith Henry, John Hammer, Gerome Escota, Teresa M Darragh, Joel M Palefsky, John T Brooks, Pragna Patel
Background: Nonavalent (9v) human papilloma virus vaccine targets high-risk (HR)-HPV types 16, 18, 31, 33, 45, 52, 58, and low-risk 6, 11. We examined prevalence, incidence, and clearance of anal and cervical HR-HPV in HIV-infected women. Methods: From 2004-2006, the SUN Study enrolled 167 women from four US cities. Anal and cervical specimens were collected annually for cytology and identification of 37 HPV types; 14 HR include: 9v 16, 18, 31, 33, 45, 52, 58; non-9v 35, 39, 51, 56, 59, 66, 68...
February 14, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29451631/-effects-of-saludarte-program-in-feeding-and-nutrition-components-in-school-children-in-mexico-city
#20
Teresa Shamah-Levy, Lucía Cuevas-Nasu, Luz María Gómez-Acosta, Ma Del Carmen Morales-Ruan, Ignacio Méndez-Gómez Humarán, Mara Nadiezhda Robles-Villaseñor, Mauricio Hernández-Ávila
OBJECTIVE: To assess the effect of Education in Nutrition and Food Assistance components of the SaludArte program in participant schools during 2013-2015. MATERIALS AND METHODS: A three cohort comparative study was used, with two type of follow-up panel structures: a complete panel and a continuous time, with a total of consisting on 1620 scholar children from 144 schools. Information on food intake, feeding behaviors, food preservation and hygiene, physical activity (PI) and anthropometry was registered...
November 2017: Salud Pública de México
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