keyword
MENU ▼
Read by QxMD icon Read
search

USV electrophysiology

keyword
https://www.readbyqxmd.com/read/24416405/discrimination-of-ultrasonic-vocalizations-by-cba-caj-mice-mus-musculus-is-related-to-spectrotemporal-dissimilarity-of-vocalizations
#1
Erikson G Neilans, David P Holfoth, Kelly E Radziwon, Christine V Portfors, Micheal L Dent
The function of ultrasonic vocalizations (USVs) produced by mice (Mus musculus) is a topic of broad interest to many researchers. These USVs differ widely in spectrotemporal characteristics, suggesting different categories of vocalizations, although this has never been behaviorally demonstrated. Although electrophysiological studies indicate that neurons can discriminate among vocalizations at the level of the auditory midbrain, perceptual acuity for vocalizations has yet to be determined. Here, we trained CBA/CaJ mice using operant conditioning to discriminate between different vocalizations and between a spectrotemporally modified vocalization and its original version...
2014: PloS One
https://www.readbyqxmd.com/read/23441094/knockout-of-nmda-receptors-in-parvalbumin-interneurons-recreates-autism-like-phenotypes
#2
John A Saunders, Valerie M Tatard-Leitman, Jimmy Suh, Eddie N Billingslea, Timothy P Roberts, Steven J Siegel
Autism is a disabling neurodevelopmental disorder characterized by social deficits, language impairment, and repetitive behaviors with few effective treatments. New evidence suggests that autism has reliable electrophysiological endophenotypes and that these measures may be caused by n-methyl-d-aspartic acid receptor (NMDAR) disruption on parvalbumin (PV)-containing interneurons. These findings could be used to create new translational biomarkers. Recent developments have allowed for cell-type selective knockout of NMDARs in order to examine the perturbations caused by disrupting specific circuits...
April 2013: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/18515444/effects-of-bifeprunox-and-aripiprazole-on-rat-serotonin-and-dopamine-neuronal-activity-and-anxiolytic-behaviour
#3
COMPARATIVE STUDY
L Dahan, H Husum, O Mnie-Filali, J Arnt, P Hertel, N Haddjeri
The atypical antipsychotic bifeprunox is a partial dopamine D(2) and 5-HT(1A) receptor agonist. Using in-vivo electrophysiological and behavioural paradigms in the rat, the effects of bifeprunox and aripiprazole were assessed on ventral tegmental area (VTA) dopamine and dorsal raphe serotonin (5-HT) cell activity and on foot shock-induced ultrasonic vocalisation (USV). In VTA, bifeprunox and aripiprazole decreased (by 20-50%) firing of dopamine neurons. Interestingly, bursting activity was markedly reduced (by 70-100%), bursting being associated with a larger synaptic dopamine release than single spike firing...
March 2009: Journal of Psychopharmacology
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"