keyword
https://read.qxmd.com/read/38535090/machine-learning-identifies-higher-survival-profile-in-extracorporeal-cardiopulmonary-resuscitation
#21
JOURNAL ARTICLE
Ruben Crespo-Diaz, Julian Wolfson, Demetris Yannopoulos, Jason A Bartos
OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival in patients with refractory out-of-hospital cardiac arrest (OHCA) caused by shockable rhythms. Further refinement of patient selection is needed to focus this resource-intensive therapy on those patients likely to benefit. This study sought to create a selection model using machine learning (ML) tools for refractory cardiac arrest patients undergoing ECPR. DESIGN: Retrospective cohort study...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38534914/extraction-and-detection-of-mitragynine-in-kratom-leaves-by-high-performance-liquid-chromatography
#22
JOURNAL ARTICLE
Karno Ng, Taehoon Ha
Mitragyna speciosa , also known as Kratom, is an evergreen tree native to Southeast Asia that has been used in traditional medicine to relieve pain. The primary active alkaloid, mitragynine, found in Kratom leaves affects the same µ-receptor as the opioids. The potential effects of Kratom leaves on humans draw international concerns. The purpose of this study is to develop an efficient extraction method for mitragynine from dried Kratom leaves. Mitragynine was extracted from grounded Kratom leaves by liquid-liquid extraction and detected by an HPLC system with a C-18 column...
March 27, 2024: Natural Product Research
https://read.qxmd.com/read/38534632/the-fragmented-picture-of-antimicrobial-resistance-in-kenya-a-situational-analysis-of-antimicrobial-consumption-and-the-imperative-for-antimicrobial-stewardship
#23
REVIEW
Aarman Sohaili, Judith Asin, Pierre P M Thomas
Antimicrobial resistance (AMR) jeopardizes the effectiveness of essential antimicrobial agents in treating infectious diseases. Accelerated by human activities, AMR is prevalent in Sub-Saharan Africa, including Kenya, due to indiscriminate antibiotic use and limited diagnostics. This study aimed to assess Kenya's AMR efforts through a situational analysis of policy efficacy, interventions, and implementation, culminating in recommendations for strengthening mitigation. Employing two methodologies, this study evaluated Kenya's AMR endeavors...
February 20, 2024: Antibiotics
https://read.qxmd.com/read/38534117/psychometric-properties-of-entrustable-professional-activity-based-objective-structured-clinical-examinations-during-transition-from-undergraduate-to-graduate-medical-education-a-generalizability-study
#24
JOURNAL ARTICLE
Manish Suneja, Kate DuChene Hanrahan, Clarence Kreiter, Jane Rowat
PURPOSE: The objective structured clinical examination (OSCE) assesses clinical competence in health sciences education. There is little research regarding the reliability and validity of using an OSCE during the transition from undergraduate to graduate medical education. The goal of this study was to measure the reliability of a unique 2-rater entrustable professional activity (EPA)-based OSCE format for transition to internship using generalizability theory for estimating reliability...
March 26, 2024: Academic Medicine
https://read.qxmd.com/read/38534094/relationship-between-siri-and-android-and-gynoid-fat-related-to-obesity-and-cardiovascular-risk-a-cross-sectional-study-of-nhanes-2017-2018
#25
JOURNAL ARTICLE
Xuanchun Zhang
OBJECTIVE: Inflammation has a crucial role in several metabolic diseases, such as obesity. The author aimed to investigate the relationship between the system inflammation response index (SIRI) and android fat composition and distribution. METHODS: Data for individuals aged 8-59 years, SIRI, android percent fat, and android-to-gynoid ratio from the 2017 to 2018 National Health and Nutrition Examination Survey were used. Weighted multiple linear regression and smooth curve fitting were used to test for linear and nonlinear associations...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38534089/learning-curve-of-ultrasound-guided-percutaneous-nephrolithotripsy-in-the-treatment-of-complex-renal-calculi
#26
JOURNAL ARTICLE
Zhaoxiang Lu, Wentie Yang, Wei He
OBJECTIVE: This study was performed to investigate the learning curve of ultrasound-guided percutaneous nephrolithotripsy (PCNL) for the treatment of complex renal calculi. METHODS: Seventy-two patients with complex renal stones who underwent ultrasound-guided PCNL by the same operator from November 2016 to September 2020 were retrospectively analyzed. The learning curve of PCNL for complex renal stones was analyzed using multifactorial cumulative sum (CUSUM) analysis and best-fit curves...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38534086/unstable-vancouver-b1-periprosthetic-femoral-fracture-fixation-a-biomechanical-comparison-between-a-novel-c-shaped-memory-alloy-implant-and-cerclage-wiring
#27
JOURNAL ARTICLE
Seog-Hyun Oh, Yu-Sung Suh, Emmanuel Eghan-Acquah, Kollerov Mikhail Yurevich, Sung-Hun Won, Min Jung Baek, Sung-Jae Lee, Sung-Woo Choi
BACKGROUND: To compare the biomechanical stability of a novel, C-shaped nickel-titanium shape memory alloy (SMA) implant (C-clip) with traditional cerclage wiring in the fixation of a Vancouver B1 (VB1) periprosthetic femoral fracture (PFF). METHODS: In total, 18 synthetic femoral fracture models were constructed to obtain unstable VB1 fracture with an oblique fracture line 8 cm below the lesser trochanter. For each model, the distal portion was repaired using a 10-hole locking plate and four distal bi-cortical screws...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38534077/synovial-sarcoma-of-the-viscera-lung-and-jejunum-a-case-report
#28
JOURNAL ARTICLE
Jixin He, Jiwei Wang, Lina Yang, Kai Wang, Maijian Wang, Jianguo Li
We report the case of a woman nearing 70 years old who was admitted to the hospital with a complaint of "epigastric distension for 1 month". Her main signs and symptoms were progressive abdominal distension and occasional abdominal pain. Computed tomography suggested an abdominal mass. She had a surgical history of synovial sarcoma (SS) of the lungs. After admission, she was diagnosed with jejunal SS following a puncture biopsy and laparoscopic surgery. This disease usually occurs in the soft tissues of the limbs, and it is extremely rare for SS to originate in the jejunum...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38534040/characterization-of-the-visually-impaired-patients-with-diabetes-mellitus-in-japan
#29
JOURNAL ARTICLE
Yuka Sugihara, Yoshihiro Takamura, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Kumiko Kato, Takao Hirano, Fumiko Murao, Miho Shimizu, Sentaro Kusuhara, Tomoya Murakami, Yuki Takenaka, Naoko Okabe, Tatsuya Jujo, Hiroto Terasaki, Daisuke Nagasato, Zhenyu Dong, Shigeo Yoshida, Shuntaro Ogura, Kanako Yasuda, Gaku Ishigooka, Osamu Sawada, Fumiaki Higashijima, Masaru Inatani
AIMS/INTRODUCTION: To conduct a multicenter survey of visually impaired patients with diabetes mellitus (DM) and to identify the physical and ocular characteristics that lead to blindness in Japan. MATERIALS AND METHODS: Visually impaired patients with diabetes mellitus in Japan were divided into blind and low-vision groups according to the World Health Organization classification. Data on parameters related to diabetes mellitus and ocular complications in the right and left eyes were collected from 19 highly advanced medical facilities and compared between the two groups...
March 27, 2024: Journal of Diabetes Investigation
https://read.qxmd.com/read/38534010/children-s-experiences-of-mask-wearing-a-systemic-review-and-narrative-synthesis
#30
REVIEW
Elin Preest, Trisha Greenhalgh, Christian Farrier, Helene-Mari van der Westhuizen
RATIONALE: Masks have been widely used as a preventative tool during the COVID-19 pandemic. However, the use of masks by children has been controversial, with international guidelines recommending a risk-based approach to national policymakers. AIMS AND OBJECTIVES: We aimed to conduct a systematic review that explores children's experiences of mask-wearing, drawing on an evidence base that describes mask-wearing in different contexts including air pollution, and to prevent the spread of infectious disease...
March 27, 2024: Journal of Evaluation in Clinical Practice
https://read.qxmd.com/read/38534007/high-hepatitis-c-cure-rates-among-patients-with-alcohol-use-at-a-safety-net-hepatitis-c-clinic
#31
JOURNAL ARTICLE
Erica Heiman, Meghan Alexander, Rebecca Zhang, Ziduo Zheng, Lesley S Miller
OBJECTIVES: We set out to examine several aspects of the relationship between alcohol use and hepatitis C virus (HCV) among a cohort of patients treated at an HCV clinic within a safety net hospital. We examined (1) the prevalence of alcohol use among patients treated for HCV, (2) the likelihood of being started on treatment among patients who reported drinking alcohol compared with those who did not, and (3) the associations between alcohol use and HCV cure. METHODS: We performed a retrospective chart abstraction study using data from the Grady Liver Clinic, a specialty HCV clinic colocated in Grady Memorial Hospital's primary care clinic and run by general internists...
March 27, 2024: Journal of Addiction Medicine
https://read.qxmd.com/read/38533880/experiences-with-pre-graduate-research-among-danish-medical-students-and-doctors
#32
JOURNAL ARTICLE
Ditte Georgina Zhang, Jawad Ahmad Zahid, Noor Al-Huda Hadi, Simon Francis Thomsen
INTRODUCTION: Pre-graduate research is popular among medical students. Concerns about time constraints and lack of mentorship have been raised in international studies. The extent to which these issues affect Danish medical students remains unclear. We therefore aimed to assess the conditions and outcomes of pre-graduate research among medical students from the University of Copenhagen. METHODS: A descriptive, cross-sectional, questionnaire-based survey on experiences from pre-graduate research was distributed to medical students and recently graduated medical doctors from the University of Copenhagen who had engaged in full-time pre-graduate research...
March 8, 2024: Danish Medical Journal
https://read.qxmd.com/read/38533857/-not-available
#33
JOURNAL ARTICLE
Malene Tanderup, Lone Schmidt, Charlotte Kroløkke, Birgitte Bruun Nielsen, Peter Humaidan
Gestational surrogacy, in which an infertile couple contracts with a woman to carry a foetus that the intended parents will raise, increases worldwide, and offers a route to parenthood for individuals and couples who otherwise have limited options. However, the situation in Denmark at present is that surrogacy with the help of healthcare professionals is illegal, and international adoption is no longer available. This review gives an overview of the legal situation of surrogacy in Denmark, the impact of the legislation, and medical issues to be aware of as healthcare professionals in the future...
March 25, 2024: Ugeskrift for Laeger
https://read.qxmd.com/read/38533849/impact-of-commonly-used-drugs-on-24-hour-urine-metanephrine-excretion
#34
JOURNAL ARTICLE
Marta Araujo-Castro, Ana M García Cano, Aura D Herrera-Martínez
No abstract text is available yet for this article.
March 27, 2024: Polish Archives of Internal Medicine
https://read.qxmd.com/read/38533848/atrial-fibrillation-comorbidities-stroke-and-mortality-in-real-world-clinical-practice
#35
JOURNAL ARTICLE
Giuseppe Boriani, Davide A Mei, Jacopo F Imberti
No abstract text is available yet for this article.
March 27, 2024: Polish Archives of Internal Medicine
https://read.qxmd.com/read/38533825/the-effect-of-an-electronic-medical-record-based-clinical-decision-support-system-on-adherence-to-clinical-protocols-in-inflammatory-bowel-disease-care-interrupted-time-series-study
#36
JOURNAL ARTICLE
Reed Taylor Sutton, Kaitlyn Delaney Chappell, David Pincock, Daniel Sadowski, Daniel C Baumgart, Karen Ivy Kroeker
BACKGROUND: Clinical decision support systems (CDSSs) embedded in electronic medical records (EMRs), also called electronic health records, have the potential to improve the adoption of clinical guidelines. The University of Alberta Inflammatory Bowel Disease (IBD) Group developed a CDSS for patients with IBD who might be experiencing disease flare and deployed it within a clinical information system in 2 continuous time periods. OBJECTIVE: This study aims to evaluate the impact of the IBD CDSS on the adherence of health care providers (ie, physicians and nurses) to institutionally agreed clinical management protocols...
March 22, 2024: JMIR Medical Informatics
https://read.qxmd.com/read/38533744/collaborative-study-for-the-establishment-of-ph-eur-biological-reference-preparation-for-human-tetanus-immunoglobulin-batch-2
#37
JOURNAL ARTICLE
P Stickings, R Tierney, J Hockley, P Rigsby, E Terao
This publication describes the outcome of a project to develop a replacement European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) for Human tetanus immunoglobulin (TIg) as well as for the World Health Organization (WHO) International Standard (IS) for Tetanus Immunoglobulin, Human. Bulk TIg was kindly provided by a European manufacturer and was used to prepare the candidate standard. The candidate standard was freeze-dried and calibrated in an international collaborative study jointly co-ordinated by the Medicines & Healthcare products Regulatory Agency (MHRA) and the European Directorate for the Quality of Medicines & HealthCare (EDQM, Council of Europe)...
2024: Pharmeuropa Bio & Scientific Notes
https://read.qxmd.com/read/38533427/writing-case-reports-can-improve-seven-components-in-clinical-reasoning
#38
JOURNAL ARTICLE
Toshinori Nishizawa, Kosuke Ishizuka, Yuki Otsuka, Toshiyuki Nakanishi, Akira Kawashima, Taiju Miyagami, Shun Yamashita
Case reports provide scientific knowledge and opportunities for new clinical research. However, it is estimated that less than 5% of cases presented by Japanese generalists at academic conferences are published due to various barriers such as the complex process of writing articles, conducting literature searches, the significant time required, the reluctance to write in English, and the challenge of selecting appropriate journals for publication. Therefore, the purpose of this opinion paper is to provide clinicians with practical tips for writing case reports that promote diagnostic excellence...
2024: International Medical Case Reports Journal
https://read.qxmd.com/read/38533294/a-review-and-discussion-of-full-time-equivalency-and-appropriate-compensation-models-for-an-adult-intensivist-in-the-united-states-across-various-base-specialties
#39
JOURNAL ARTICLE
Michael Nurok, Brigid C Flynn, Marc Pineton de Chambrun, Mina Kazemian, Joel Geiderman, Mark E Nunnally
OBJECTIVES: Physicians with training in anesthesiology, emergency medicine, internal medicine, neurology, and surgery may gain board certification in critical care medicine upon completion of fellowship training. These clinicians often only spend a portion of their work effort in the ICU. Other work efforts that benefit an ICU infrastructure, but do not provide billing opportunities, include education, research, and administrative duties. For employed or contracted physicians, there is no singular definition of what constitutes an intensive care full-time equivalent (FTE)...
April 2024: Critical care explorations
https://read.qxmd.com/read/38533177/the-impact-of-an-intern-s-clinical-guidebook-on-easing-the-transition-of-new-interns-into-the-united-states-healthcare-system
#40
JOURNAL ARTICLE
Andranik Bedross, Bekure B Siraw, Ayah Alkhidir, Eli A Zaher, Parth Patel, Ashok Kumar, Peter Bostoros, Hasan Sqour, Pardeep Kumar, Shayet Hossain Eshan
This study explores the efficacy of an intern's clinical guidebook in facilitating the transition of categorical internal medicine interns into the United States healthcare system. New interns, particularly foreign medical graduates, face multifaceted challenges during their initial year of residency. The research, conducted at Ascension Saint Joseph Hospital in Chicago, employed a quasi-experimental pre-post design involving 20 interns. Participants were provided with an intern's clinical guidebook, and their knowledge was assessed through pre and post exams...
February 2024: Curēus
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