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https://www.readbyqxmd.com/read/29353401/temporal-analysis-of-factors-associated-with-eat-10-in-outpatients-with-oropharyngeal-dysphagia-from-a-tertiary-care-clinic
#1
R S Bartlett, J E Moore, S L Thibeault
Self-perception of disease is increasingly recognized as a determinant of health. The Eating Assessment Tool-10 (EAT-10) is a functional health status questionnaire that measures the symptomatic severity of dysphagia from the patient's perspective. The objective of this work was to identify factors (demographics, clinical variables, swallowing physiology, health-related quality of life) associated with longitudinal change in EAT-10 scores in outpatients with oropharyngeal dysphagia at a multi-disciplinary, tertiary care clinic...
January 20, 2018: Dysphagia
https://www.readbyqxmd.com/read/29352532/the-impact-of-severe-mental-disorders-and-psychotropic-medications-on-sexual-health-and-its-implications-for-clinical-management
#2
Angel L Montejo, Laura Montejo, David S Baldwin
Sexual dysfunction often accompanies severe psychiatric illness and can be due to both the mental disorder itself and the use of psychotropic treatments. Many sexual symptoms resolve as the mental state improves, but treatment-related sexual adverse events tend to persist over time, and are unfortunately under-recognized by clinicians and scarcely investigated in clinical trials. Treatment-emergent sexual dysfunction adversely affects quality of life and may contribute to reduce treatment adherence. There are important differences between the various compounds in the incidence of adverse sexual effects, associated with differences in mechanisms of action...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29352460/pelvic-floor-muscle-function-and-quality-of-life-in-post-menopausal-women-with-and-without-pelvic-floor-dysfunction
#3
Isabella Parente Ribeiro Frota, Adriana Bombonato Oliveira Rocha, José Ananias Vasconcelos Neto, Camila Teixeira Moreira Vasconcelos, Thais Fontes De Magalhaes, Sara Arcanjo Lino Karbage, Kathiane Lustosa Augusto, Simony Lira Do Nascimento, Jorge Millem Haddad, Leonardo Robson Pinheiro Sobreira Bezerra
This study aims to compare pelvic floor muscle (PFM) function in post-menopause women with and without pelvic floor dysfunction (PFD) and the relationship between PFM function and quality of life MATERIAL AND METHODS: a case-control study with 216 post-menopause women with (n=126) and without PFD (n=90). PFM function was assessed by digital vaginal palpation using PERFECT scale. Specific quality of life was evaluated by King's Health Questionnaire for women with urinary incontinence and Prolapse Quality-of-Life Questionnaire for women with pelvic organ prolapse...
January 20, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29352360/quality-of-life-in-obstructive-sleep-apnea-is-related-to-female-gender-and-comorbid-insomnia
#4
Mehmet Sezai Tasbakan, Canan Gunduz, Sebnem Pirildar, Ozen K Basoglu
PURPOSE: Obstructive sleep apnea (OSA) is a common sleep disorder affecting health-related quality of life (QoL), and OSA severity is not a reliable indicator for QoL. The aim of this study was (1) to evaluate the impact of gender on QoL and (2) to identify the predictors of QoL in OSA patients. METHODS: World Health Organization Quality of Life Scale short form (WHOQOL-Bref) was used for evaluating QoL in OSA patients undergoing polysomnography in sleep laboratory of a university hospital...
January 19, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29351979/when-is-the-right-time
#5
Jacky Reid, Andrea Nolan, Marian Scott
Veterinary medicine is veering further towards prolongation of life at all costs, without the safeguard of being able to robustly measure quality of life. Jacky Reid, Andrea Nolan and Marian Scott discuss major steps forward in the ability to measure changes in health-related quality of life.
January 20, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29351819/patient-reported-outcomes-in-older-adults-with-obstructive-sleep-apnea-treated-with-continuous-positive-airway-pressure-therapy
#6
Jennifer Pallansch, Yiping Li, James Bena, Lu Wang, Nancy Foldvary-Schaefer
STUDY OBJECTIVES: Although continuous positive airway pressure (CPAP) therapy is regarded as the gold standard treatment for obstructive sleep apnea (OSA) in adults, outcomes in older patients are limited. This study examines the effect of CPAP therapy in older adults with OSA (older than 60 years) compared to younger adults (age 18 to 60 years) to inform the current standard of practice. METHODS: We performed a retrospective study with a convenience sample to compare responses to CPAP treatment in older versus younger adults with OSA using validated, patient-reported outcomes (PROs)...
January 16, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29351517/caregiver-difficulties-scale-cds-translation-and-psychometric-evaluation-among-iranian-mothers-of-cerebral-palsy-children
#7
Ata Farajzadeh, Malek Amini, Saman Maroufizadeh, Champa J Wijesinghe
The aim of this study was to investigate of psychometric properties of the Caregiver Difficulties Scale (CDS) for Iranian caregivers of children with cerebral palsy (CP). After a forward-backward translation, the Persian version of CDS (P-CDS) was administered to 151 Iranian mothers of CP children. The confirmatory factor analysis (CFA) was applied to measure the factor structure of P-CDS. The reliability was evaluated by examining internal consistency and test-retest method over a 2-week period using Cronbach's alpha and the intraclass correlation coefficient (ICC), respectively...
January 2018: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/29351310/healthy-ageing-at-work-efficacy-of-group-interventions-on-the-mental-health-of-nurses-aged-45-and-older-results-of-a-randomised-controlled-trial
#8
Imad Maatouk, Andreas Müller, Peter Angerer, Renate Schmook, Christoph Nikendei, Kirsten Herbst, Melanie Gantner, Wolfgang Herzog, Harald Gündel
OBJECTIVE: This multicentre, randomised controlled trial (RCT) aimed to evaluate the efficacy of a small-group intervention promoting successful ageing at work in older nurses (aged ≥45). METHOD: A sample of 115 nurses aged ≥45 from 4 trial sites in Germany were randomly assigned to either the intervention group (IG), that received a small-group intervention of seven weekly sessions of 120 min with a booster session after six weeks or to a wait-list control condition (WLC)...
2018: PloS One
https://www.readbyqxmd.com/read/29351296/hybrid-genome-assembly-and-annotation-of-paenibacillus-pasadenensis-strain-r16-reveals-insights-on-endophytic-life-style-and-antifungal-activity
#9
Alessandro Passera, Luca Marcolungo, Paola Casati, Milena Brasca, Fabio Quaglino, Chiara Cantaloni, Massimo Delledonne
Bacteria of the Paenibacillus genus are becoming important in many fields of science, including agriculture, for their positive effects on the health of plants. However, there are little information available on this genus compared to other bacteria (such as Bacillus or Pseudomonas), especially when considering genomic information. Sequencing the genomes of plant-beneficial bacteria is a crucial step to identify the genetic elements underlying the adaptation to life inside a plant host and, in particular, which of these features determine the differences between a helpful microorganism and a pathogenic one...
2018: PloS One
https://www.readbyqxmd.com/read/29351222/association-between-work-related-stress-and-health-related-quality-of-life-the-impact-of-socio-demographic-variables-a-cross-sectional-study-in-a-region-of-central-italy
#10
Giuseppe La Torre, Cristina Sestili, Alice Mannocci, Alessandra Sinopoli, Massimiliano De Paolis, Sara De Francesco, Laura Rapaccini, Marco Barone, Valentina Iodice, Bruno Lojodice, Sabina Sernia, Simone De Sio, Angela Del Cimmuto, Maria De Giusti
The aim of this work is investigate relationship between health-related quality of life and work-related stress and the impact of gender, education level, and age on this relationship. A cross-sectional study was conducted among workers of various setting in Rome and Frosinone. Work-related stress was measured with a demand-control questionnaire and health-related functioning by SF (short form)-12 health survey. There were 611 participants. Men reported high mental composite summary (MCS) and physical composite summary (PCS)...
January 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29351154/predictors-of-health-related-quality-of-life-in-irritable-bowel-syndrome-patients-compared-with-healthy-individuals
#11
Raymond Addante, Bruce Naliboff, Wendy Shih, Angela P Presson, Kirsten Tillisch, Emeran A Mayer, Lin Chang
BACKGROUND: Irritable bowel syndrome (IBS) reduces health-related quality of life (HRQOL). It is unclear how having IBS modifies the impact of gastrointestinal (GI), psychosocial, and somatic symptom variables on HRQOL compared with healthy controls (HCs). AIMS: (1) Determine psychosocial, somatic, and physical status variables most predictive of HRQOL in IBS and HCs and (2) determine if IBS status modifies relationships between predictive factors and HRQOL. METHODS: IBS patients and HCs completed validated questionnaires measuring GI symptoms, psychosocial/somatic variables, and physical [physical component score (PCS)] and mental [mental component score (MCS)] HRQOL via the Short-Form-36...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29351130/comparative-effectiveness-of-low-volume-time-efficient-resistance-training-versus-endurance-training-in-patients-with-heart-failure
#12
Gregers Winding Munch, Jaya Birgitte Rosenmeier, Morten Petersen, Anders Rasmussen Rinnov, Ulrik Winning Iepsen, Bente Klarlund Pedersen, Stefan Peter Mortensen
PURPOSE: Cardiorespiratory fitness is positively related to heart failure (HF) prognosis, but lack of time and low energy are barriers for adherence to exercise. We, therefore, compared the effect of low-volume time-based resistance exercise training (TRE) with aerobic moderate-intensity cycling (AMC) on maximal and submaximal exercise capacity, health-related quality of life, and vascular function. METHODS: Twenty-eight HF patients (New York Heart Association class I-II) performed AMC (n = 14) or TRE (n = 14)...
January 18, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29350456/a-prospective-study-of-family-predictors-of-health-related-quality-of-life-in-pediatric-brain-tumor-survivors
#13
Lauren F Quast, Peter C Phillips, Yimei Li, Anne E Kazak, Lamia P Barakat, Matthew C Hocking
BACKGROUND: The objective of this study was to examine prospectively the associations between family functioning at the end of tumor-directed treatment and the health-related quality of life (HRQL) of pediatric brain tumor survivors (PBTSs) approximately 9 months later. PROCEDURE: Thirty-five PBTS (age 6-16 years) and their mothers completed measures of family functioning and survivor HRQL within 5 months of completing tumor-directed therapy (baseline) and again approximately 9 months later (follow-up)...
January 19, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29350378/eq-5d-studies-in-cardiovascular-diseases-in-eight-central-and-eastern-european-countries-a-systematic-review-of-the-literature
#14
Paulina Batóg, Fanni Rencz, Márta Péntek, László Gulácsi, Krzysztof J Filipiak, Valentina Prevolnik Rupel, Judit Simon, Valentin Brodszky, Petra Baji, Jakub Závada, Guenka Petrova, Alexandru Rotar, Dominik Golicki
BACKGROUND: The measurement of health-related quality of life (HRQOL) by validated generic instruments, such as EQ-5D, becomes an increasingly important tool for the assessment of health care in a wide range of different diagnoses. AIM: To systematically review EQ-5D literature generated in cardiovascular diseases in eight selected Central and Eastern Europe (CEE) countries. METHODS: A structured literature search was conducted in MEDLINE, EMBASE, Web of Science, CINAHL, PsycINFO, the Cochrane Library and the EuroQol website up to November 2016...
January 19, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29350345/measurement-invariance-and-general-population-reference-values-of-the-promis-profile-29-in-the-uk-france-and-germany
#15
Felix Fischer, Chris Gibbons, Joël Coste, Jose M Valderas, Matthias Rose, Alain Leplège
PURPOSE: Comparability of patient-reported outcome measures over different languages is essential to allow cross-national research. We investigate the comparability of the PROMIS Profile 29, a generic health-related quality of life measure, in general population samples in the UK, France, and Germany and present general population reference values. METHODS: A web-based survey was simultaneously conducted in the UK (n = 1509), France (1501), and Germany (1502)...
January 19, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29350344/the-relationship-between-exercise-dose-and-health-related-quality-of-life-with-a-phase-iii-cardiac-rehabilitation-program
#16
Borja Del Pozo-Cruz, Graeme Carrick-Ranson, Stacey Reading, Paul Nolan, Lance C Dalleck
PURPOSE: To quantify the relationship between the change in exercise dose and health-related quality of life (HRQoL) in a cohort of patients participating in a community-based phase-3 cardiac rehabilitation (CR) program. METHODS: A retrospective, pre-experimental (no control group) design of 58 participants that completed a phase-3, 12-week exercise-based CR program was used to test the current hypothesis. Self-reported HRQoL (36-Item Short Form Health Survey Version 2, SF-36v2) was assessed prior and after completing the CR program...
January 19, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29350332/sleep-in-ankylosing-spondylitis-and-non-radiographic-axial-spondyloarthritis-associations-with-disease-activity-gender-and-mood
#17
Alison Wadeley, Emily Clarke, Shaaron Leverment, Raj Sengupta
The study aims were to assess the prevalence of good or poor sleep in a cohort of axial spondyloarthritis patients and to investigate its correlation with a range of objectively and subjectively measured variables in order to develop a model for distinguishing good from poor sleepers. Five hundred ninety-eight patients with ankylosing spondylitis and 61 with non-radiographic axial spondyloarthritis completed the Jenkins Sleep Evaluation Questionnaire. Measures of disease activity, mobility, function, mood, fatigue, quality of life, work productivity, night-time pain and general health were gathered...
January 19, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29350177/antidepressant-medication-in-a-german-cohort-of-patients-with-alzheimer-s-disease%C3%A2
#18
Philipp Hessmann, Richard Dodel, Erika Baum, Matthias J Müller, Greta Paschke, Bernhard Kis, Jan Zeidler, Mike Klora, Jens-Peter Reese, Monika Balzer-Geldsetzer
OBJECTIVE: The use of antidepressant drugs in dementia patients is associated with the risk of adverse events, and the evidence for relevant effects is scarce. We aimed to determine the associations between the prescription of antidepressants and patients' sociodemographic (e.g., age, gender, living situation) and clinical characteristics (e.g., disease severity, neuropsychiatric symptoms). MATERIALS AND METHODS: We included 395 institutionalized and community-dwelling patients with Alzheimer's disease (AD) across all severity stages of dementia in a cross-sectional study design...
January 19, 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29349713/patient-reported-outcomes-of-catheter-based-accelerated-partial-breast-brachytherapy-and-whole-breast-irradiation-a-single-institution-experience
#19
Krishan R Jethwa, Mohamed M Kahila, Kristin C Mara, William S Harmsen, David M Routman, Geralyn M Pumper, Kimberly S Corbin, Jeff A Sloan, Kathryn J Ruddy, Tina J Hieken, Sean S Park, Robert W Mutter
PURPOSE: Accelerated partial breast irradiation (APBI) and whole breast irradiation (WBI) are treatment options for early-stage breast cancer. The purpose of this study was to compare patient-reported-outcomes (PRO) between patients receiving multi-channel intra-cavitary brachytherapy APBI or WBI. METHODS: Between 2012 and 2015, 131 patients with ductal carcinoma in situ (DCIS) or early stage invasive breast cancer were treated with adjuvant APBI (64) or WBI (67) and participated in a PRO questionnaire...
January 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29349708/cost-effectiveness-of-empagliflozin-for-the-treatment-of-patients-with-type-2-diabetes-mellitus-at-increased-cardiovascular-risk-in-greece
#20
George Gourzoulidis, Charalampos Tzanetakos, Ioannis Ioannidis, Apostolos Tsapas, Georgia Kourlaba, Giannis Papageorgiou, Nikos Maniadakis
BACKGROUND AND OBJECTIVE: Type 2 diabetes mellitus (T2DM) is frequently associated with co-morbidities that exacerbate cardiovascular (CV) risk. CV disease is the leading cause of death in people with diabetes across the world and accounts for approximately half the deaths in the T2DM population. Hence, the objective of present study was to evaluate the cost-effectiveness of empagliflozin, in addition to standard of care (SoC), for the treatment of adult patients with T2DM and high CV risk in Greece...
January 18, 2018: Clinical Drug Investigation
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