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https://www.readbyqxmd.com/read/29775778/the-genus-cordyceps-an-extensive-review-of-its-traditional-uses-phytochemistry-and-pharmacology
#1
REVIEW
Opeyemi Joshua Olatunji, Jian Tang, Adesola Tola, Florence Auberon, Omolara Oluwaniyi, Zhen Ouyang
The genus Cordyceps has about 750 identified species which are distributed in many regions of the World, but mainly found in South Asia, Europe and North America. The species of the genus are highly priced and are widely used as food and medicine for the treatment of various ailments. This present review compiles literature information on the ethno-medicinal, phytochemistry and pharmacological properties of species in the genus Cordyceps. In addition, the review also suggest recommendations for the future researches...
May 15, 2018: Fitoterapia
https://www.readbyqxmd.com/read/29775226/moxibustion-for-cephalic-version-of-breech-presentation
#2
REVIEW
Judith M Schlaeger, Cynthia L Stoffel, Jeanie L Bussell, Hui Yan Cai, Miho Takayama, Hiroyoshi Yajima, Nobuari Takakura
Moxibustion, a form of traditional Chinese medicine (TCM), is the burning of the herb moxa (Folium Artemisiae argyi or mugwort) over acupuncture points. It is often used in China to facilitate cephalic version of breech presentation. This article reviews the history, philosophy, therapeutic use, possible mechanisms of action, and literature pertaining to its use for this indication. For moxibustion, moxa can be rolled into stick form, placed directly on the skin, or placed on an acupuncture needle and ignited to warm acupuncture points...
May 18, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29774927/-interpretation-on-chinese-surgeons-consensus-opinion-for-the-definition-of-gastric-stump-cancer-version-2018
#3
Zhidong Gao, Kewei Jiang, Yingjiang Ye, Shan Wang
Gastric stump cancer(GSC) is defined as newly developed remnant stomach cancer following gastrectomy. This definition initially referred to carcinoma detected in the remnant stomach more than 5 years after the primary surgery for a benign disease. Subsequently, this timeframe was extended to 10 years after the primary surgery for a malignant disease. Recently, the concept of "carcinoma in the remnant stomach(CRS)" proposed by the Japanese Gastric Cancer Association was introduced in China. The new definition encompasses all carcinomas arising in the remnant stomach following gastrectomy, irrespective of the histology of the primary lesion, extent of resection, or reconstruction method...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29773004/anti-inflammatory-activity-of-chemical-constituents-isolated-from-the-willow-bracket-medicinal-mushroom-phellinus-igniarius-agaricomycetes
#4
Zhe Jiang, Mei Jin, Wei Zhou, Ren Li, Yan Zhao, Xuejun Jin, Gao Li
Nuclear factor-κB (NF-κB) has an important role in immune response and inflammation. Phellinus igniarius (known as Sang huang in traditional Chinese medicine) has various pharmacologic effects. In this study, 19 chemical constituents (1-19) were isolated from the fruiting bodies of Ph. igniarius. Their structures were elucidated based on data from nuclear magnetic resonance spectroscopy and comparison with the literature. Overall, 3 compounds (2, 7, and 11) from this species were reported, to our knowledge for the first time...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29772791/compounds-identification-in-semen-cuscutae-by-ultra-high-performance-liquid-chromatography-uplcs-coupled-to-electrospray-ionization-mass-spectrometry
#5
Ying Zhang, Hui Xiong, Xinfang Xu, Xue Xue, Mengnan Liu, Shuya Xu, Huan Liu, Yan Gao, Hui Zhang, Xiangri Li
Semen Cuscutae is commonly used in traditional Chinese medicine and contains a series of compounds such as flavonoids, chlorogenic acids and lignans. In this study, we identified different kinds of compositions by ultra-high-performance liquid chromatography (UPLC) coupled to electrospray ionization mass spectrometry (MS). A total of 45 compounds were observed, including 20 chlorogenic acids, 23 flavonoids and 2 lignans. 23 of them are reported for the first time including 6- O -caffeoyl- β -glucose, 3- O -(4'- O -Caffeoylglucosyl) quinic acid, etc...
May 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29772715/effects-of-sparassis-crispa-in-medical-therapeutics-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#6
Le Thi Nhu Ngoc, You-Kwan Oh, Young-Jong Lee, Young-Chul Lee
In this study, we investigated the therapeutic potential and medical applications of Sparassis crispa ( S. crispa ) by conducting a systematic review of the existing literature and performing a meta-analysis. The original efficacy treatment of the mushroom extract is considered primarily and searched in electronic databases. A total of 623 articles were assessed, 33 randomized controlled experiments were included after the manual screening, and some papers, review articles, or editorials that did not contain data were excluded...
May 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29771635/pathogenesis-based-treatments-in-primary-sjogren-s-syndrome-using-artificial-intelligence-and-advanced-machine-learning-techniques-a-systematic-literature-review
#7
Nathan Foulquier, Pascal Redou, Christophe Le Gal, Bénédicte Rouvière, Jacques-Olivier Pers, Alain Saraux
Big data analysis has become a common way to extract information from complex and large datasets among most scientific domains. This approach is now used to study large cohorts of patients in medicine. This work is a review of publications that have used artificial intelligence and advanced machine learning techniques to study physio pathogenesis-based treatments in pSS. A systematic literature review retrieved all articles reporting on the use of advanced statistical analysis applied to the study of systemic autoimmune diseases (SADs) over the last decade...
May 17, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29771251/-ebm-guidelines-protocols-knowledge-attitudes-and-utilization-in-the-era-of-law-on-professional-responsibility-and-safety-of-health-care
#8
Silvia Minozzi, Francesca Ruggiero, Matteo Capobussi, Marien González-Lorenzo, Micaela La Regina, Alessandro Squizzato, Lorenzo Moja, Francesco Orlandini
INTRODUCTION: <AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">The knowledge of principles and methods of Evidence Based Medicine (EBM) and the use of Clinical Practice Guidelines to inform clinical decisions are recognised as key instruments to improve the quality of care. In Italy the Parliament has revised the legal system that rules the responsibilities of health professionals and health care safety, prescribing health professionals to adhere to guidelines and good practice recommendations...
May 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29771224/discipline-specific-competency-based-curricula-for-leadership-learning-in-medical-specialty-training
#9
Sandra Turner, Ming-Ka Chan, Judy McKimm, Graham Dickson, Timothy Shaw
Purpose Doctors play a central role in leading improvements to healthcare systems. Leadership knowledge and skills are not inherent, however, and need to be learned. General frameworks for medical leadership guide curriculum development in this area. Explicit discipline-linked competency sets and programmes provide context for learning and likely enhance specialty trainees' capability for leadership at all levels. The aim of this review was to summarise the scholarly literature available around medical specialty-specific competency-based curricula for leadership in the post-graduate training space...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29770862/is-latin-america-ready-to-identify-anaplastic-large-cell-lymphoma-in-breast-implants-patients-regional-encounter-during-the-national-plastic-surgery-meeting-in-cancun-mexico
#10
EDITORIAL
Guillermo Ramos-Gallardo, Jesus Cuenca-Pardo, Lazaro Cardenas-Camarena, Hector Duran-Vega, Eugenio Rodríguez-Olivares, Jorge Enrique Bayter-Marin, Gerardo Levelier De Doig Alvear, Guillermo Vazquez, Montserrat Fontbona-Torres, Ricardo Galán-Suárez, Gabriela Guzman-Stein, Sergio Guzmán-Padilla, Guillermo Echeverría-Roldán, Jose Fernando Silva-Gavarrete, Alfonso Vallarta-Rodríguez, Livia Contreras-Bulnes, Carlos Guillemro Oaxaca-Escobar, Isabel Caravantes-Cortes, María Eugenia Flores, Jorge Cowes-McGowen, María Liz Maciel-Sosa, Ricardo Delgado-Binasco, Linda Rincón-Rubio
INTRODUCTION: Anaplastic large cell lymphoma associated with breast implants is receiving increased attention. Most cases have been reported in Europe, North America (USA and Canada), Australia and New Zealand. Fewer cases have been reported in Latin America (including Mexico), Africa and Asia. METHODS: This report was delivered during our national plastic surgery meeting in Cancun in May 2017. Before the meeting, two participants reviewed the literature. The review was performed using the following information sources: PubMed, Embase, Cochrane, Fisterra, Google Scholar and LILACS, with entries from 1980 to August 2015 in several languages (English, Spanish, French and Portuguese)...
May 16, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29770054/new-vaccine-administration-practice-recommendations-from-the-canadian-immunization-guide
#11
C Jensen, D Moore, C Mah, O Baclic, S Marchant-Short
Background: The Canadian Immunization Guide (CIG) is published online by the Public Health Agency of Canada and summarizes guidance on vaccines for human use into a single resource. Chapters are reviewed and updated on a regular basis. Vaccine administration is a critical part of any immunization program. Recently, the CIG chapter on vaccine administration practices was updated. Objective: To provide highlights of recent changes to the Vaccine Administration Practices chapter of the CIG...
November 2, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29769295/indoor-mould-exposure-asthma-and-rhinitis-findings-from-systematic-reviews-and-recent-longitudinal-studies
#12
REVIEW
Denis Caillaud, Benedicte Leynaert, Marion Keirsbulck, Rachel Nadif
Starting from the Institute of Medicine (IOM) and World Health Organization (WHO) reports, this review provides an overview of the literature published from 2006 to 2017 on the associations between indoor mould exposure and asthma and rhinitis separately in children and adults with a focus on longitudinal epidemiological studies.A systematic search of peer-reviewed literature was performed, including systematic reviews and meta-analyses, longitudinal, incident case-control and panel studies. 61 publications were identified reporting visible mould or mould odour or quantitative assessment of culturable fungi or mould species...
June 30, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29769100/what-did-the-go4health-policy-research-project-contribute-to-the-policy-discourse-on-the-sustainable-development-goals-a-reflexive-review
#13
REVIEW
Vannarath Te, Nadia Floden, Sameera Hussain, Claire E Brolan, Peter S Hill
BACKGROUND: In 2012, the European Commission funded Go4Health-Goals and Governance for Global Health, a consortium of 13 academic research and human rights institutions from both Global North and South-to track the evolution of the Sustainable Development Goals (SDGs), and provide ongoing policy advice. This paper reviews the research outputs published between 2012 and 2016, analyzing the thematic content of the publications, and the influence on global health and development discourse through citation metrics...
May 16, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29768977/primary-care-physicians-perceptions-of-practice-improvement-as-a-professional-responsibility-a-cross-sectional-study
#14
Christopher R Stephenson, Christopher M Wittich, Joel E Pacyna, Matthew K Wynia, Omar Hasan, Jon C Tilburt
Continuous quality improvement is a component of professionalism. Maintenance of Certification (MOC) is a mechanism in the USA for physicians to keep current with medical knowledge and contribute to practice improvement. Little is known about primary care physicians' perceptions of the practice improvement (Part IV) components of MOC. We aimed to determine primary care physicians' perceptions of their professional responsibility to participate in Part IV MOC. This was a cross-sectional study of primary care physicians using the American Medical Association Masterfile...
December 2018: Medical Education Online
https://www.readbyqxmd.com/read/29767332/recent-development-in-antihyperalgesic-effect-of-phytochemicals-anti-inflammatory-and-neuro-modulatory-actions
#15
REVIEW
Ajeet Kumar Singh, Sanjay Kumar, Manjula Vinayak
INTRODUCTION: Pain is an unpleasant sensation triggered by noxious stimulation. It is one of the most prevalent conditions, limiting productivity and diminishing quality of life. Non steroidal anti inflammatory drugs (NSAIDs) are widely used as pain relievers in present day practice as pain is mostly initiated due to inflammation. However, due to potentially serious side effects, long term use of these antihyperalgesic drugs raises concern. Therefore there is a demand to search novel medicines with least side effects...
May 16, 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/29766808/a-review-on-plant-antimicrobials-of-past-decade
#16
Preet Amol Singh, Sapna D Desai, Jasbir Singh
As per WHO reports, about three-quarters (65-80%) of the world's population seeks plants or plant-derived natural products for various diseases. The slow discovery of new synthetic molecules and rising resistance in microbes against existing ones has triggered an alarm for speeding up the development process for new molecules. Traditional system(s) of medicine and plant resources has been foresighted again by researchers to circumvent the situation. This review represents various plant genera which, either as a whole plant or their parts, have been reported possessing antimicrobial properties during the last decade...
May 16, 2018: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29766296/characterization-of-in-vivo-metabolites-in-rat-urine-following-an-oral-dose-of-masitinib-by-liquid-chromatography-tandem-mass-spectrometry
#17
Adnan A Kadi, Sawsan M Amer, Hany W Darwish, Mohamed W Attwa
Masitinib (MST) is an orally administered drug that targets mast cells and macrophages, important cells for immunity, by inhibiting a limited number of tyrosine kinases. It is currently registered in Europe and USA for the treatment of mast cell tumors in dogs. AB Science announced that the European Medicines Agency has accepted a conditional marketing authorization application for MST to treat amyotrophic lateral sclerosis. In our work, we focused on studying in vivo metabolism of MST in Sprague-Dawley rats...
May 15, 2018: Chemistry Central Journal
https://www.readbyqxmd.com/read/29766256/monogenic-systemic-lupus-erythematosus-insights-in-pathophysiology
#18
REVIEW
Ezgi Deniz Batu
Systemic lupus erythematosus (SLE) is a complex disease with different genetic, immunologic, and environmental factors contributing to the pathogenesis. Monogenic SLE could help us understand the main phases of immune dysregulation in SLE. The aim of this review is to summarize the current knowledge on monogenic SLE with the implications of the respective genes on disease pathogenesis. A comprehensive literature search on monogenic SLE was conducted utilizing the Cochrane Library and MEDLINE/PubMed databases...
May 15, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29766208/-adequate-anti-infective-treatment-importance-of-individual-dosing-and-application
#19
A Brinkmann, A C Röhr, A Köberer, T Fuchs, W A Krüger, C König, D Richter, M A Weigand, O R Frey
Sepsis-induced changes in pharmacokinetic parameters are a well-known problem in intensive care medicine. Dosing of antibiotics in this setting is therefore challenging. Alterations to the substance-specific kinetics of anti-infective substances have an effect on the distribution and excretion processes in the body. Increased clearance and an increased distribution volume (Vd ) and particularly compromized organ function with reduced antibiotic elimination are often encountered in patients with sepsis. Renal replacement treatment, which is frequently used in intensive care medicine, represents a substantial intervention in this system...
May 15, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29765977/systems-pharmacology-based-approach-of-connecting-disease-genes-in-genome-wide-association-studies-with-traditional-chinese-medicine
#20
Jihye Kim, Minjae Yoo, Jimin Shin, Hyunmin Kim, Jaewoo Kang, Aik Choon Tan
Traditional Chinese medicine (TCM) originated in ancient China has been practiced over thousands of years for treating various symptoms and diseases. However, the molecular mechanisms of TCM in treating these diseases remain unknown. In this study, we employ a systems pharmacology-based approach for connecting GWAS diseases with TCM for potential drug repurposing and repositioning. We studied 102 TCM components and their target genes by analyzing microarray gene expression experiments. We constructed disease-gene networks from 2558 GWAS studies...
2018: International Journal of Genomics
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