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https://www.readbyqxmd.com/read/28432823/-gerimedjc-the-twitter-complement-to-the-traditional-format-geriatric-medicine-journal-club
#1
Amanda I Gardhouse, Laura Budd, Seu Y C Yang, Camilla L Wong
Twitter is a public microblogging platform that overcomes physical limitations and allows unrestricted participation beyond academic silos, enabling interactive discussions. Twitter-based journal clubs have demonstrated growth, sustainability, and worldwide communication, using a hashtag (#) to follow participation. This article describes the first year of #GeriMedJC, a monthly 1-hour live, 23-hour asynchronous Twitter-based complement to the traditional-format geriatric medicine journal club. The Twitter moderator tweets from the handle @GeriMedJC; encourages use of #GeriMedJC; and invites content experts, study authors, and followers to participate in critical appraisal of medical literature...
April 22, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28432354/structural-and-functional-analysis-of-lysozyme-after-treatment-with-dielectric-barrier-discharge-plasma-and-atmospheric-pressure-plasma-jet
#2
Sooho Choi, Pankaj Attri, Inhwan Lee, Jeongmin Oh, Ji-Hye Yun, Ji Hoon Park, Eun Ha Choi, Weontae Lee
The variation in the biological function of proteins plays an important role in plasma medicine and sterilization. Several non-thermal plasma sources with different feeding gases are used worldwide for plasma treatment, including dielectric barrier discharge (DBD) and atmospheric-pressure plasma jet (APPJ) as the most commonly used sources. Therefore, in the present work, we used both DBD and APPJ plasma sources with N2 and air as feeding gases to evaluate the effects on the structural, thermodynamic, and activity changes of enzymes...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28431457/precision-medicine-and-pharmacogenetics-what-does-oncology-have-that-addiction-medicine-does-not
#3
Henry R Kranzler, Rachel V Smith, Robert Schnoll, Afaf Moustafa, Emma Greenstreet-Akman
BACKGROUND AND AIMS: Precision, personalized or stratified medicine, which promises to deliver the right treatment to the right patient, is a topic of international interest in both the lay press and the scientific literature. A key aspect of precision medicine is the identification of biomarkers that predict the response to medications (i.e. pharmacogenetics). We examined why, despite the great strides that have been made in biomarker identification in many areas of medicine, only in oncology has there been substantial progress in their clinical implementation...
April 21, 2017: Addiction
https://www.readbyqxmd.com/read/28430703/evidence-based-recommendations-for-pediatric-orthopaedic-practice
#4
Kishore Mulpuri, Emily K Schaeffer, H Kerr Graham, Mininder S Kocher, James Sanders, Ira Zaltz
BACKGROUND: Evidence-based medicine has become the cornerstone to guide clinical practice decision-making. Evidence-based medicine integrates the strongest available evidence with clinical expertise to make decisions about clinical care. The quality of the evidence depends upon the soundness of the study methodology to allow for meaningful interpretation of the clinical results. The purpose of this review is to analyze the methodological design and clinical findings of published pediatric orthopaedic studies to determine their ability to change or influence clinical practice...
April 20, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28428157/texting-and-mobile-phone-app-interventions-for-improving-adherence-to-preventive-behavior-in-adolescents-a-systematic-review
#5
Sherif M Badawy, Lisa M Kuhns
BACKGROUND: Many preventable behaviors contribute to adolescent mortality and morbidity. Non-adherence to preventive measures represents a challenge and has been associated with worse health outcomes in this population. The widespread use of electronic communication technologies by adolescents, particularly the use of text messaging (short message service, SMS) and mobile phones, presents new opportunities to intervene on risk and preventive risk behavior, but little is known about their efficacy...
April 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28427912/hepataprotective-effects-of-ginsenoside-rg1-a-review
#6
REVIEW
Yan Gao, Shifeng Chu, Zhao Zhang, Naihong Chen
BACKGROUND AND ETHNOPHARMACOLOGICAL RELEVANCE: Ginseng has been used as efficient tonic and for the treatment of various diseases including hepatic disorders. Ginseng saponins, also known as ginsenosides, are principal constituents and have been treated to be responsible for disparate ginseng health benefits. The current review mainly focuses on ginsenoside Rg1, a compound isolated from traditional Chinese herbal medicine Panax ginseng Meyer. AIMS: To summary the hepataprotective effects and related mechanisms of ginsenoside Rg1, we conclude this review by combining the literature and our own researches...
April 17, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28427466/determinants-of-orphan-drugs-prices-in-france-a-regression-analysis
#7
Daria Korchagina, Aurelie Millier, Anne-Lise Vataire, Samuel Aballea, Bruno Falissard, Mondher Toumi
BACKGROUND: The introduction of the orphan drug legislation led to the increase in the number of available orphan drugs, but the access to them is often limited due to the high price. Social preferences regarding funding orphan drugs as well as the criteria taken into consideration while setting the price remain unclear. The study aimed at identifying the determinant of orphan drug prices in France using a regression analysis. METHODS: All drugs with a valid orphan designation at the moment of launch for which the price was available in France were included in the analysis...
April 21, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28427321/in-silico-assessment-of-biomedical-products-the-conundrum-of-rare-but-not-so-rare-events-in-two-case-studies
#8
Marco Viceconti, Claudio Cobelli, Tarek Haddad, Adam Himes, Boris Kovatchev, Mark Palmer
In silico clinical trials, defined as "The use of individualized computer simulation in the development or regulatory evaluation of a medicinal product, medical device, or medical intervention," have been proposed as a possible strategy to reduce the regulatory costs of innovation and the time to market for biomedical products. We review some of the the literature on this topic, focusing in particular on those applications where the current practice is recognized as inadequate, as for example, the detection of unexpected severe adverse events too rare to be detected in a clinical trial, but still likely enough to be of concern...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28426117/identifying-the-gaps-in-nepalese-migrant-workers-health-and-well-being-a-review-of-the-literature
#9
Padam P Simkhada, Pramod R Regmi, Edwin van Teijlingen, Nirmal Aryal
Background: The health and well-being of migrant workers from low-income countries is often neglected in travel medicine. This article uses Nepal as a case study to highlight key issues affecting this particular group of international travellers. Methods: This narrative review used a comprehensive systematic literature search to identify relevant studies on Nepal. The included articles were thematically analysed leading to four key themes or risk factors. Results: The search found 18 articles from which we identified 3 key themes related directly to migrant workers: (1) sexual risk taking; (2) occupational health and (3) lifestyles, and a fourth theme related to partners and family of migrant workers who are left behind in Nepal...
July 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28425891/teaching-psychology-in-medicine-the-context-methodologies-and-doctor-s-professional-identity
#10
REVIEW
Silvia Ouakinin
INTRODUCTION: Teaching Psychology in medical curriculum has been the subject of numerous dissertations that focus on the relevance of this knowledge for doctors, at a general level. METHODS: A non-systematic review of the relevant literature, particularly from the last decade, as well as national and international recommendations addressing the need for integration of behavioural and social sciences in medical training, was performed. RESULTS: The literature supports the existence of preconceptions and negative attitudes towards the role of psychology in medical education, demonstrated by research in various european and american universities...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28425044/systematic-review-for-geo-authentic-lonicerae-japonicae-flos
#11
REVIEW
Xingyue Yang, Yali Liu, Aijuan Hou, Yang Yang, Xin Tian, Liyun He
In traditional Chinese medicine, Lonicerae Japonicae Flos is commonly used as anti-inflammatory, antiviral, and antipyretic herbal medicine, and geo-authentic herbs are believed to present the highest quality among all samples from different regions. To discuss the current situation and trend of geo-authentic Lonicerae Japonicae Flos, we searched Chinese Biomedicine Literature Database, Chinese Journal Full-text Database, Chinese Scientific Journal Full-text Database, Cochrane Central Register of Controlled Trials, Wanfang, and PubMed...
April 19, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28424057/personalized-medicine-in-europe-not-yet-personal-enough
#12
Antonello Di Paolo, François Sarkozy, Bettina Ryll, Uwe Siebert
BACKGROUND: Personalized medicine has the potential to allow patients to receive drugs specific to their individual disease, and to increase the efficiency of the healthcare system. There is currently no comprehensive overview of personalized medicine, and this research aims to provide an overview of the concept and definition of personalized medicine in nine European countries. METHODS: A targeted literature review of selected health databases and grey literature was conducted to collate information regarding the definition, process, use, funding, impact and challenges associated with personalized medicine...
April 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28423954/the-design-and-scale-up-of-spray-dried-particle-delivery-systems
#13
Ali Al-Khattawi, Andrew Bayly, Andy Phillips, David Wilson
The rising demand for pharmaceutical particles with tailored physico-chemical properties has opened new markets for the spray drying technology especially for solubility enhancement, improvement of inhalation medicines and stabilization of biopharmaceuticals. Despite this, the literature on spray drying is scattered and often does not address the fundamental principles underpinning the robust development of pharmaceutical products. It is therefore necessary to present a clearer picture of the field and highlight the principles and factors influencing particle design and scale-up...
April 19, 2017: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/28422961/characterization-of-the-mechanism-of-drug-drug-interactions-from-pubmed-using-mesh-terms
#14
Yin Lu, Bryan Figler, Hong Huang, Yi-Cheng Tu, Ju Wang, Feng Cheng
Identifying drug-drug interaction (DDI) is an important topic for the development of safe pharmaceutical drugs and for the optimization of multidrug regimens for complex diseases such as cancer and HIV. There have been about 150,000 publications on DDIs in PubMed, which is a great resource for DDI studies. In this paper, we introduced an automatic computational method for the systematic analysis of the mechanism of DDIs using MeSH (Medical Subject Headings) terms from PubMed literature. MeSH term is a controlled vocabulary thesaurus developed by the National Library of Medicine for indexing and annotating articles...
2017: PloS One
https://www.readbyqxmd.com/read/28421273/-definition-classification-clinical-diagnosis-and-prognosis-of-fibromyalgia-syndrome-updated-guidelines-2017-and-overview-of-systematic-review-articles
#15
W Eich, K-J Bär, M Bernateck, M Burgmer, C Dexl, F Petzke, C Sommer, A Winkelmann, W Häuser
BACKGROUND: The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was scheduled for April 2017. METHODS: The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n =8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest...
April 18, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28421029/a-historical-view-of-motion-sickness-a-plague-at-sea-and-on-land-also-with-military-impact
#16
Doreen Huppert, Judy Benson, Thomas Brandt
Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was made from the Greek period beginning with Homer in 800 BC to the late Roman period and ending with Aetios Amidenos in 600 AD, as well as in the Chinese medical classics dating from around 300 AD. Major aspects are the following: body movements caused by waves were identified in all cultures as the critical stimuli...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28420539/hta-and-decision-making-processes-in-central-eastern-and-south-eastern-europe-results-from-a-survey
#17
Leticia García-Mochón, Jaime Espín Balbino, Antonio Olry de Labry Lima, Araceli Caro Martinez, Eva Martin Ruiz, Román Pérez Velasco
OBJECTIVE: To gain knowledge and insights on health technology assessment (HTA) and decision-making processes in Central, Eastern and South Eastern Europe (CESEE) countries. METHODS: A cross-sectional study was performed. Based on the literature, a questionnaire was developed in a multi-stage process. The questionnaire was arranged according to 5 broad domains: (i) introduction/country settings; (ii) use of HTA in the country; (iii) decision-making process; (iv) implementation of decisions; and (v) HTA and decision-making: future challenges...
March 31, 2017: Health Policy
https://www.readbyqxmd.com/read/28420381/operations-research-in-global-health-a-scoping-review-with-a-focus-on-the-themes-of-health-equity-and-impact
#18
REVIEW
Beverly D Bradley, Tiffany Jung, Ananya Tandon-Verma, Bassem Khoury, Timothy C Y Chan, Yu-Ling Cheng
BACKGROUND: Operations research (OR) is a discipline that uses advanced analytical methods (e.g. simulation, optimisation, decision analysis) to better understand complex systems and aid in decision-making. Herein, we present a scoping review of the use of OR to analyse issues in global health, with an emphasis on health equity and research impact. A systematic search of five databases was designed to identify relevant published literature. A global overview of 1099 studies highlights the geographic distribution of OR and common OR methods used...
April 18, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28418091/newsworthiness-versus-scientific-impact-are-the-most-highly-cited-urology-papers-the-most-widely-disseminated-in-the-media
#19
E M O'Connor, G J Nason, F O'Kelly, R P Manecksha, S Loeb
BACKGROUND: Discordance exists between scientific impact and media attention. Altmetrics are non-traditional measures of impact which are composite scores that include social media and traditional media sharing of an article. OBJECTIVE: To assess whether a correlation exists between newsworthiness (Altmetric score) and the scientific impact markers such as citation analysis, impact factors and levels of evidence. MATERIALS AND METHODS: The top 5 most cited articles for the year 2014 and 2015 from the top 10 ranking urology journals (scientific impact group) were identified...
April 18, 2017: BJU International
https://www.readbyqxmd.com/read/28417090/role-of-traditional-islamic-and-arabic-plants-in-cancer-therapy
#20
REVIEW
Rizwan Ahmad, Niyaz Ahmad, Atta Abbas Naqvi, Adeeb Shehzad, Mastour Safer Al-Ghamdi
ETHNO PHARMACOLOGICAL RELEVANCE: This review article underlines individual Traditional Islamic and Arabic plant (TAI) and their role in treating cancer. The aim of the study is to specifically evaluate the progress of herbs, Arabic and Islamic traditional herbs in particular, applied in cancer treatment, so far. MATERIALS AND METHODS: Islamic and Arabic plants were selected and identified through different literature survey using "Google scholar", "Web of science", "Scopus" and "PubMed"...
April 2017: Journal of Traditional and Complementary Medicine
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