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Mehmet Kaynar, Ozcan Kilic, Talat Yurdakul
OBJECTIVES: To determine the efficacy of tramadol in premature ejaculation (PE) treatment compared with placebo. METHODS: A single-blind, placebo-controlled, crossover study was conducted with 60 lifelong (primary) patients with PE. The patients were randomized into 2 groups, each consisting of 30 patients, who took tramadol or placebo on demand. PE was defined as an intravaginal ejaculation latency time of ≤60 seconds in 90% of intercourse episodes. The efficacy of the drugs was assessed using the intravaginal ejaculation latency time, ability of ejaculation control, and sexual satisfaction scores after an 8-week treatment period...
January 2012: Urology
(no author information available yet)
In equation 6 of the Research Article "Effects of age on dopamine and seratonin receptors measured by positron tomography in the living human brain" by D. F. Wong et al. (21 Dec., p. 1393) C(p)(t) in the denominator of the last term should have been A(cb)(t). This does not affect the rest of the derivation. In the caption of figure 1, the first word, "Decrease," should have been "Change." The data in parts A and B of figure 3 should have been regraphed on common axes to facilitate comparison. A corrected figure 3 is shown below...
March 8, 1985: Science
Marzena N Binczycka-Anholcer
Aggressive behaviour should be considered as the feedback in relation with the health condition of society. Aggression may be considered as instinct behaviour or acquired social behaviour. If we are studying the theory of aggressive behaviour, we should take into consideration psychosocial and biological features, the influence of neurotransmitters: seratonin, dopamine and some biochemical markers just like the level of cholesterol, troigliceroids and testosterone. Aggressive behaviour, physical and mental violence has negative influence on physical health, fitness and efficiency...
2002: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Y Kapran, J Bauersfeld, M Anlauf, B Sipos, G Klöppel
We analyzed pancreatic endocrine tumors (PETs) from 200 patients for the incidence of multihormonality and entrapped islets and correlated the results with clinicopathological features. Our series included 86 cases (43%) of functioning PET and 114 cases (57%) of nonfunctioning PET. Classified according to the WHO classification, there were 32 well-differentiated benign PETs, 85 well-differentiated PETs with uncertain behavior, and 83 well-differentiated malignant PETs. All tumors were immunostained for pancreatic hormones (insulin, glucagon, somatostatin, and pancreatic polypeptide) and for additional hormones such as gastrin, vasoactive intestinal polypeptide, calcitonin, seratonin, and adrenocorticotropic hormone...
April 2006: Virchows Archiv: An International Journal of Pathology
Rowan T Chlebowski, Jung A Kim, Nananda F Col
Vasomotor symptoms associated with menopause or cancer therapies represent an increasingly common problem for breast cancer survivors given the increasing use of ovarian suppression in premenopausal women and aromatase inhibitors in postmenopausal women. Although estrogen and/or progestin effectively reduce vasomotor symptoms, a recent Women's Health Initiative (WHI) randomized trial identified an unfavorable risk/benefit balance on life-threatening diseases, including increased breast cancer, for combined estrogen plus progestin use in otherwise healthy postmenopausal women...
December 2003: Seminars in Oncology
Ian G Morgan
Myopia is among the most common refractive errors and is associated with the greatest risk of pathological outcomes. Most animals, including humans, are born with hyperopic errors. During development, axial elongation of the eye occurs and is regulated through a vision-dependent process, known as emmetropisation The extremely rapid changes in the prevalence of myopia and the dependence of myopia on the level of education indicate that there are very strong environmental impacts on the development of myopia...
September 2003: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Sheri Kanner, Vanya Hamrin, Margaret Grey
TOPIC: Prevalence and interventions for depression in youth with type 1 diabetes. PURPOSE: To explore the co-morbidity of youth with diabetes and psychiatric conditions, and evaluate the relationship of youth with co-morbid depression and diabetes on glycemic control, quality of life, family support, behavioral problems, attributional style, and self-esteem. SOURCES: Relevant literature in both child and adolescent populations of psychiatry, psychology, and nursing...
January 2003: Journal of Child and Adolescent Psychiatric Nursing
Neil Wilson
The absence or diminution of light is potentially an anxiety-arousing situation for, perhaps, all of us. Even a cursory look at the origin myths of many cultures reveals the chaotic, destructive, and dangerous aspects of darkness. Additionally, language reflects the same qualities metaphorically and symbolically. Developmentally, the arrival of the darkness of evening potentially signals object loss and ego regression. But factors other than ubiquitous references to a consideration of light and darkness are relevant...
August 2002: Psychoanalytic Review
Mark L Wolraich
BACKGROUND: Psychotropic medications have become an integral component in the treatment of children with mental illnesses. METHODS: Selective reviews of the empirical evidence for the efficacy of psychotropic medications and studies of their use patterns were reviewed. RESULTS: Very strong efficacy for at least the short-term benefits and safety of stimulant medications was found and some good efficacy and safety evidence for the treatment of anxiety and depressive disorders with seratonin reuptake inhibitors (SSRI) was also found...
February 2003: Journal of Child Psychology and Psychiatry, and Allied Disciplines
D J Goldstein, K I Roon, W W Offen, N M Ramadan, L A Phebus, K W Johnson, J M Schaus, M D Ferrari
BACKGROUND: Triptans (5-HT(1B/1D) receptor agonists) are effective drugs for acute migraine, but the side-effect of coronary vasoconstriction restricts their use in patients who are at risk of coronary artery disease. We have studied the efficacy of LY334370, a selective serotonin 1F (5-HT(1F)) receptor agonist with preclinical efficacy and no vasoconstriction, for migraine relief. METHODS: We gave LY334370 (20, 60, or 200 mg) or placebo to 99 outpatients with moderate or severe migraine headaches in a double blind, parallel group study...
October 13, 2001: Lancet
M C. Sokoloski
Neurocardiogenic syncope is the most common form of syncope in children. The most widely accepted mechanism of its etiology is a vigorous contraction of the heart due to relative hypovolemia leading to stimulation of C-fibers and sympathetic withdrawal. Episodes usually occur with an upright position and are preceded by a typical prodrome. A classic history is paramount to the diagnosis. Tilt testing aids in the diagnosis in certain cases. The cornerstone of therapy is maintaining adequate hydration and avoiding situations that may lead to harm with syncopal events...
August 2001: Progress in Pediatric Cardiology
D L Dunner
Comorbidity of depression complicates diagnosis and makes treatment more difficult. The broad efficacy of selective-seratonin reuptake inhibitors makes these compounds of particular benefit as monotherapy for depression comorbid with anxiety disorders, especially panic disorder and obsessive-compulsive disorder.
January 1997: Clinical Performance and Quality Health Care
J A Hardin, P D Brockway, D G Gall
The aim of this study was to characterize and compare the effect of atrial natriuretic peptide (ANP) on ileal transport function in two common laboratory animals, the Hooded-Lister rat and the New Zealand White rabbit. ANP 1 microM produced a maximal increase in short circuit current (Isc) that was Cl- dependent in both rat and rabbit. The maximal response in rat tissue was twice the magnitude of that seen in the rabbit. Furthermore, the rabbit Isc response was rapid and transient compared with that of the rat...
March 1998: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
G D Talbott
Intensive work needs to continue on the genetic characteristics of the X-Y chromosome. There needs to be further clarification of the allele penetrants and the oncogenes, as well as determination of the specific chromosomes. It is now apparent that the neurotransmitters, particularly dopamine, seratonin, and norepinephrine, as related to the MFB receptor sites, are a determining factor in the presence or absence of this disease. However, the exact manner in which these neurotransmitters and receptor sites act, particularly in terms of the feed-back systems, remains obscure...
June 1991: Journal of the Medical Association of Georgia
F Johansson, L von Knorring
Forty patients with pain syndromes of both organic and psychogenic origin of at least 6 months' duration were included in a double-blind controlled study of a new rather selective serotonin uptake inhibitor, Zimelidine, versus placebo. Patients in the Zimelidine group experienced significantly more pain relief and tended to be able to reduce their need for analgesics more often than the patients in the placebo group. In the Zimelidine group 4 patients were excluded due to nausea and intestinal troubles versus only 1 patient in the placebo group...
August 1979: Pain
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