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https://www.readbyqxmd.com/read/29453443/role-of-the-mesolimbic-dopamine-system-in-relief-learning
#1
Dana Mayer, Evelyn Kahl, Taygun C Uzuneser, Markus Fendt
The relief from an aversive event is rewarding. Since organisms are able to learn which environmental cues can cease an aversive event, relief learning helps to better cope with future aversive events. Literature data suggest that relief learning is affected in various psychopathological conditions, such as anxiety disorders. Here, we investigated the role of the mesolimbic dopamine system in relief learning. Using a relief learning procedure in Sprague Dawley rats, we applied a combination of behavioral experiments with anatomical tracing, c-Fos immunohistochemistry, and local chemogenetic and pharmacological interventions to broadly characterize the role of the mesolimbic dopamine system...
February 5, 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29453036/identifying-the-relative-importance-of-non-suicidal-self-injury-features-in-classifying-suicidal-ideation-plans-and-behavior-using-exploratory-data-mining
#2
Taylor A Burke, Ross Jacobucci, Brooke A Ammerman, Marilyn Piccirillo, Michael S McCloskey, Richard G Heimberg, Lauren B Alloy
Individuals with a history of non-suicidal self-injury (NSSI) are at alarmingly high risk for suicidal ideation (SI), planning (SP), and attempts (SA). Given these findings, research has begun to evaluate the features of this multi-faceted behavior that may be most important to assess when quantifying risk for SI, SP, and SA. However, no studies have examined the wide range of NSSI characteristics simultaneously when determining which NSSI features are most salient to suicide risk. The current study utilized three exploratory data mining techniques (elastic net regression, decision trees, random forests) to address these gaps in the literature...
January 31, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29448136/improving-functional-outcomes-in-women-with-borderline-personality-disorder-and-ptsd-by-changing-ptsd-severity-and-post-traumatic-cognitions
#3
Melanie S Harned, Chelsey R Wilks, Sara C Schmidt, Trevor N Coyle
Although functional impairment typically improves during evidence-based psychotherapies (EBPs) for borderline personality disorder (BPD), functional levels often remain suboptimal after treatment. The present pilot study evaluated whether and how integrating PTSD treatment into an EBP for BPD would improve functional outcomes. Participants were 26 women with BPD, PTSD, and recent suicidal and/or self-injurious behavior who were randomized to receive one year of Dialectical Behavior Therapy (DBT) or DBT with the DBT Prolonged Exposure (DBT PE) protocol for PTSD...
February 6, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29446553/children-s-moral-experiences-of-crisis-management-in-a-child-mental-health-setting
#4
Marjorie Montreuil, Catherine Thibeault, Linda McHarg, Franco A Carnevale
The experiences of children related to conflict and crisis management in child mental health settings, especially those aged 12 and below, have been rarely studied. This study examined the moral experiences of children related to conflict and crisis management and the related use of restraint and seclusion in a child mental health setting. A 5-month focused ethnography using a participatory hermeneutic framework was conducted in a day hospital programme for children with severe disruptive disorders within a mental health institute...
February 15, 2018: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29434657/mental-health-status-and-suicidal-thoughts-and-behaviors-of-migrant-children-in-eastern-coastal-china-in-comparison-to-urban-children-a-cross-sectional-survey
#5
Jingjing Lu, Feng Wang, Pengfei Chai, Dongshuo Wang, Lu Li, Xudong Zhou
Purpose: Although adolescents' mental health problems and self-injurious thoughts and behaviors (SITBs) have been a serious public health concern worldwide, descriptions of risk factors for SITBs often fail to take migration into account. There are roughly 35.8 million migrant children in China who, with their parents, moved from original rural residence to urban areas. Little is known about migrant children's mental health status and levels of SITBs. This study aims to explore the mental health status and SITBs of migrant children living in eastern coastal China in comparison to their urban counterparts...
2018: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29429009/brief-report-self-injurious-behaviors-in-preschool-children-with-autism-spectrum-disorder-compared-to-other-developmental-delays-and-disorders
#6
G N Soke, S A Rosenberg, C R Rosenberg, R A Vasa, L-C Lee, C DiGuiseppi
We compared the prevalence of self-injurious behaviors (SIB) in preschoolers aged 30-68 months with autism spectrum disorder (ASD) (n = 691) versus other developmental delays and disorders (DD) (n = 977) accounting for sociodemographic, cognitive, and medical factors. SIB prevalence was higher in ASD versus all DD [adjusted odds-ratio (aOR) 2.13 (95% confidence interval (95% CI) 1.53, 2.97)]. In subgroup analyses, SIB prevalence was higher in ASD versus DD without ASD symptoms [aOR 4.42 (95% CI 2.66, 7...
February 10, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29417652/persistence-of-self-injury-aggression-and-property-destruction-in-children-and-adults-with-tuberous-sclerosis-complex
#7
L Wilde, K Wade, K Eden, J Moss, P J de Vries, C Oliver
BACKGROUND: Individuals with tuberous sclerosis complex (TSC) are at increased risk of developing self-injurious behaviour. The persistence of this deleterious behaviour over years is reported in aetiologically heterogeneous samples to be between 60% and 80% but is unknown for TSC. METHOD: In this study, we determined the 3-year persistence of self-injury in a sample (n = 52) of children (with and without ID) and adults (with ID) with TSC and examined characteristics associated with persistence...
February 8, 2018: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29409473/attention-deficit-hyperactivity-disorder-and-nonsuicidal-self-injury-in-a-clinical-sample-of-adolescents-the-role-of-comorbidities-and-gender
#8
Judit Balázs, Dóra Győri, Lili Olga Horváth, Gergely Mészáros, Dóra Szentiványi
BACKGROUND: The aim of the present study was to investigate the possible association between attention-deficit hyperactivity disorder (ADHD) and non-suicidal self-injury (NSSI) with special focus on the role of comorbidities and gender in a clinical sample of adolescents with both a dimensional and a categorical approach to psychopathology. METHODS: Using a structured interview, the Mini International Neuropsychiatric Interview Kid and a self-rated questionnaire, the Deliberate Self-Harm Inventory, the authors examined 202 inpatient adolescents (aged: 13-18 years) in the Vadaskert Child and Adolescent Psychiatric Hospital and Outpatient Clinic, Budapest, Hungary...
February 6, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29407359/characterizing-gender-differences-in-nonsuicidal-self-injury-evidence-from-a-large-clinical-sample-of-adolescents-and-adults
#9
Sarah E Victor, Jennifer J Muehlenkamp, Nicole A Hayes, Gregory J Lengel, Denise M Styer, Jason J Washburn
While nonsuicidal self-injury (NSSI) is common in both men and women, research exploring the intersection of NSSI and gender has been limited by the use of small samples of males drawn primarily from non-clinical populations. To address these limitations, we analyzed data from a large sample of patients enrolled in an NSSI partial hospitalization program (PHP) to compare males and females across several variables, including NSSI characteristics, correlates, and pre-post treatment outcomes. Results indicated similar NSSI characteristics and treatment outcomes for males and females, with few exceptions...
February 2, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29403130/suicidal-nonorganophosphate-poisoning-in-a-tertiary-hospital-in-south-india-nature-prevalence-risk-factors
#10
Rohit Ninan Benjamin, Thambu David, Ramya Iyadurai, K S Jacob
Background: People who deliberately ingest poisons commonly present to emergency departments of hospitals in India. However, there is a dearth of information on poisoning using nonorganophosphorus pesticides. Methods: This prospective, hospital-based study attempted to examine the nonorganophosphorus poisons used to attempt suicide. Data on sociodemographic characteristics of patients, site and source of poisons, co-ingested substances, premeditation, and reason for poisoning were collected...
January 2018: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29402877/functional-neuroanatomy-of-secondary-self-injurious-behavior
#11
Sophie Peeters, Jesse Skoch, Hiromi Holt, Lynn Mubita, Eileen A Choudhary, Kavan P Vadivelu, Donald L Gilbert, Steve W Wu, Alaine C Keebaugh, Ellen Air, Sudhakar Vadivelu
BACKGROUND: Secondary self-injurious behavior (SSIB) is underreported and predominantly not associated with suicide. In both adults and children, SSIB can cause intractable self-harm and is associated with a variety of clinical disorders, particularly those involving dysfunctional motor control. METHODS: We performed a literature review evaluating the clinical efficacy of deep-brain stimulation (DBS) as modulating SSIB observations and review current progress in preclinical SSIB animal studies...
February 3, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29393828/differentiating-suicide-attempters-from-suicide-ideators-the-role-of-capability-for-suicide
#12
Yaxuan Ren, Jianing You, Xu Zhang, Jiyi Huang, Bradley T Conner, Rui Sun, Sian Xu, Min-Pei Lin
OBJECTIVES: This study examined whether different components of capability for suicide (i.e., fearlessness about death, pain tolerance, pain insensitivity, preparation for suicide, suicide plan, and courage), as well as painful and provocative events, nonsuicidal self-injury, depressive symptoms, and hopelessness, could distinguish between suicide attempters, suicide ideators, and non-suicidal controls. METHOD: A total of 930 Chinese adolescents completed questionnaires, and a multinomial logistic regression was conducted to identify factors that could distinguish between the three groups...
February 2, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/29388895/the-role-of-negative-affect-and-self-concept-clarity-in-predicting-self-injurious-urges-in-borderline-personality-disorder-using-ecological-momentary-assessment
#13
J Wesley Scala, Kenneth N Levy, Benjamin N Johnson, Yogev Kivity, William D Ellison, Aaron L Pincus, Stephen J Wilson, Michelle G Newman
Deficits in identity as well as negative affect have been shown to predict self-injurious and suicidal behaviors in individuals with borderline personality disorder (BPD). However, less is known about the interactive effects of these two predictors. We examined the moderating effect of a particular component of identity, self-concept, on the relationship between negative affect and self-injurious urges utilizing ecological momentary assessments. Outpatients diagnosed with either BPD (n = 36) or any anxiety disorder but no BPD (n = 18) completed surveys throughout the day over a 21-day period...
January 2018: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29386447/-underlying-mechanisms-of-methamphetamine-induced-self-injurious-behavior-and-lethal-effects-in-mice
#14
Tomohisa Mori, Toshiko Sawaguchi
Relatively high doses of psychostimulants induce neurotoxicity on the dopaminergic system and self-injurious behavior (SIB) in rodents. However the underlying neuronal mechanisms of SIB remains unclear. Dopamine receptor antagonists, N-methyl-D-aspartic acid (NMDA) receptor antagonists, Nitric Oxide Synthase (NOS) inhibitors and free radical scavengers significantly attenuate methamphetamine-induced SIB. These findings indicate that activation of dopamine as well as NMDA receptors followed by radical formation and oxidative stress, especially when mediated by NOS activation, is associated with methamphetamine-induced SIB...
2018: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/29384458/out-of-touch-interoceptive-deficits-are-elevated-in-suicide-attempters-with-eating-disorders
#15
April Smith, Lauren Forrest, Elizabeth Velkoff
People with eating disorders have elevated interoceptive deficits and risk for self-injurious behaviors (SIBs). Across two eating disorder samples, the relationship between interoceptive deficits (IDs) and SIBs was tested. Study 1 (n = 100) found that suicide attempters and those engaging in non-suicidal self-injury (NSSI) had greater IDs than those with no self-injury history. Lack of access to emotion regulation strategies accounted for the link between IDs and SIBs. In Study 2 (n = 92) multiple suicide attempters had greater IDs than single attempters and those engaging in NSSI; however, the latter two groups did not differ from one another...
January 2018: Eating Disorders
https://www.readbyqxmd.com/read/29378872/eye-complications-from-self-injury-in-a-child
#16
Tina Felfeli, Kamiar Mireskandari
No abstract text is available yet for this article.
January 29, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29374003/mobile-health-technology-interventions-for-suicide-prevention-protocol-for-a-systematic-review-and-meta-analysis
#17
Ruth Melia, Kady Francis, Jim Duggan, John Bogue, Mary O'Sullivan, Derek Chambers, Karen Young
BACKGROUND: Previous research has reported that two of the major barriers to help-seeking for individuals at risk of suicide are stigma and geographical isolation. Mobile technology offers a potential means of delivering evidence-based interventions with greater specificity to the individual, and at the time that it is needed. Despite documented motivation by at-risk individuals to use mobile technology to track mental health and to support psychological interventions, there is a shortfall of outcomes data on the efficacy of mobile health (mHealth) technology on suicide-specific outcomes...
January 26, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29369662/on-the-potential-for-iatrogenic-effects-of-psychiatric-crisis-services-the-example-of-dialectical-behavior-therapy-for-adult-women-with-borderline-personality-disorder
#18
Trevor N Coyle, Jennifer A Shaver, Marsha M Linehan
OBJECTIVE: Although previous research has suggested that people with a history of using psychiatric crisis services are at higher risk for suicide, it is unclear whether this link is attributable to individual risk factors or iatrogenic effects of service utilization. We examined this question by analyzing data from a randomized controlled trial of dialectical behavior therapy (DBT), a treatment for highly suicidal individuals in which patients took advantage of crisis services less than those in the comparison condition...
February 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29368233/risk-factors-for-self-injurious-behavior-in-an-inpatient-psychiatric-sample-of-children-with-autism-spectrum-disorder-a-naturalistic-observation-study
#19
Benjamin L Handen, Carla A Mazefsky, Robin L Gabriels, Kahsi A Pedersen, Meredith Wallace, Matthew Siegel
Limited information about self-injurious behavior (SIB) is known for children and adolescents with Autism Spectrum Disorder (ASD) who require intensive behavioral health interventions. We examined risk-factors for SIB in 302 individuals with ASD (ages 4-20) admitted to six specialized psychiatric inpatient units. Seventy-four percent were reported by a caregiver to display SIB, however, only 25% were observed to engage in daily SIB during hospitalization. Those exhibiting SIB across environments had significantly higher ratings on caregiver questionnaires of SIB severity...
January 24, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29366448/nonsuicidal-self-injury-in-adolescents
#20
Paul L Plener, Michael Kaess, Christian Schmahl, Stefan Pollak, Jörg M Fegert, Rebecca C Brown
BACKGROUND: 25-35% of adolescents in random samples drawn from German schools have been found to have manifested at least one episode of nonsuicidal self-injury (NSSI). The prevalence in samples from child and adolescent psychiatric clinics is approximately 50%. NSSI can arise as a symptom in the setting of various types of mental illness. METHODS: This review is based on a selective literature search carried out in the PubMed, PsycINFO, and Cochrane Library databases, with special consideration of regional study samples...
January 19, 2018: Deutsches Ärzteblatt International
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