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university of california irvine

Navid Alem, Joseph Rinehart, Brian Lee, Doug Merrill, Safa Sobhanie, Kyle Ahn, Ran Schwarzkopf, Maxime Cannesson, Zeev Kain
BACKGROUND: Efforts to mitigate costs while improving surgical care quality have received much scrutiny. This includes the challenging issue of readmission subsequent to hospital discharge. Initiatives attempting to preclude readmission after surgery require planned and unified efforts extending throughout the perioperative continuum. Patient optimization prior to discharge, enhanced disease monitoring, and seamless coordination of care between hospitals and community providers is integral to this process...
2016: Perioperative Medicine
Thrissia Koralek, Miryha G Runnerstrom, Brandon J Brown, Chukwuemeka Uchegbu, Tania B Basta
Objectives. We examined the role of outbreak information sources through four domains: knowledge, attitudes, beliefs, and stigma related to the 2014 Ebola virus disease (EVD) outbreak. Methods. We conducted an online survey of 797 undergraduates at the University of California, Irvine (UCI) and Ohio University (OU) during the peak of the outbreak. We calculated individual scores for domains and analyzed associations to demographic variables and news sources. Results. Knowledge of EVD was low and misinformation was prevalent...
2016: PLoS Currents
Simone L Vernez, Victor Huynh, Kathryn Osann, Zhamshid Okhunov, Jaime Landman, Ralph V Clayman
BACKGROUND: We hypothesized that surgical skills assessment could aid in the selection process of medical student applicants to a surgical program. Recently, crowdsourcing has been shown to provide an accurate assessment of surgical skills at all levels of training. We compared expert and crowd assessment of surgical tasks performed by resident applicants during their interview day at the urology program at the University of California, Irvine. MATERIALS AND METHODS: Twenty-five resident interviewees performed four tasks: open square knot tying, laparoscopic peg transfer, robotic suturing, and skill task 8 on the LAP Mentor™ (Simbionix Ltd...
October 11, 2016: Journal of Endourology
Bhakti Hansoti, Mark I Langdorf, Linda S Murphy
INTRODUCTION: Open access (OA) medical publishing is growing rapidly. While subscription-based publishing does not charge the author, OA does. This opens the door for "predatory" publishers who take authors' money but provide no substantial peer review or indexing to truly disseminate research findings. Discriminating between predatory and legitimate OA publishers is difficult. METHODS: We searched a number of library indexing databases that were available to us through the University of California, Irvine Libraries for journals in the field of emergency medicine (EM)...
September 2016: Western Journal of Emergency Medicine
Ashkaun Shaterian, Jessica Gandy, Shadi Lalezari, Sarah Smith, Keyianoosh Paydar
BACKGROUND: Post-mastectomy breast reconstruction is commonly performed in the United States with numerous options available to patients and providers. This study evaluated patient race and provider in prediction of patient satisfaction following post-mastectomy breast reconstruction. METHODS: The patient satisfaction for women who underwent post mastectomy breast reconstruction at University of California, Irvine Medical Center was evaluated between 2012 and 2014, randomly using Press Ganey Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) surveys...
May 2016: World Journal of Plastic Surgery
C Hellmuth, K L Lindsay, O Uhl, C Buss, P D Wadhwa, B Koletzko, S Entringer
BACKGROUND/OBJECTIVES: Elevated pre-pregnancy BMI (pBMI) and excess gestational weight gain (GWG) constitute important prenatal exposures which may program adiposity and disease risk in offspring. The objective of this study is to investigate the influence of pBMI and GWG on the maternal metabolomic profile across pregnancy, and to identify associations with birthweight. SUBJECTS/METHODS: This is a longitudinal prospective study of 167 non-diabetic women carrying a singleton pregnancy...
August 29, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Bruce J Tromberg, Zheng Zhang, Anaïs Leproux, Thomas D O'Sullivan, Albert E Cerussi, Philip M Carpenter, Rita S Mehta, Darren Roblyer, Wei Yang, Keith D Paulsen, Brian W Pogue, Shudong Jiang, Peter A Kaufman, Arjun G Yodh, So Hyun Chung, Mitchell Schnall, Bradley S Snyder, Nola Hylton, David A Boas, Stefan A Carp, Steven J Isakoff, David Mankoff
The prospective multicenter ACRIN 6691 trial was designed to evaluate whether changes from baseline to mid-therapy in a diffuse optical spectroscopic imaging (DOSI)-derived imaging endpoint, the tissue optical index (TOI), predict pathologic complete response (pCR) in women undergoing breast cancer neoadjuvant chemotherapy (NAC). DOSI instruments were constructed at the University of California, Irvine (Irvine, CA), and delivered to six institutions where 60 subjects with newly diagnosed breast tumors (at least 2 cm in the longest dimension) were enrolled over a 2-year period...
October 15, 2016: Cancer Research
Jannett Nguyen, Michael A Liu, Rohini J Patel, Keli Tahara, Annie L Nguyen
BACKGROUND: There is growing data on complementary and alternative medicine (CAM) preferences among college students. While several studies have focused on undergraduate students, there is limited data on graduate students. MATERIALS AND METHODS: Cross sectional analysis of undergraduate and graduate students seeking medical care at the University of California Irvine's Student Health Center (SHC). The survey assessed previous CAM use and preferences for future CAM use and education...
August 2016: Complementary Therapies in Clinical Practice
Yi Wang, Yi Li, Weilin Pu, Kathryn Wen, Yin Yao Shugart, Momiao Xiong, Li Jin
Efficiency, memory consumption, and robustness are common problems with many popular methods for data analysis. As a solution, we present Random Bits Forest (RBF), a classification and regression algorithm that integrates neural networks (for depth), boosting (for width), and random forests (for prediction accuracy). Through a gradient boosting scheme, it first generates and selects ~10,000 small, 3-layer random neural networks. These networks are then fed into a modified random forest algorithm to obtain predictions...
2016: Scientific Reports
Jay M Bhatt, Harrison W Lin, Neil Bhattacharyya
Importance: Tinnitus is a common problem for millions of individuals and can cause substantial negative effects on their quality of life. A large epidemiologic study of tinnitus and its management patterns in the US adult population is lacking. Objectives: To quantify the epidemiologic features and effect of tinnitus and to analyze the management of tinnitus in the United States relative to the 2014 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) clinical practice guidelines...
October 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
Pin Lim, Chi Keong Goh, Kay Chen Tan
Class imbalance problems, where the number of samples in each class is unequal, is prevalent in numerous real world machine learning applications. Traditional methods which are biased toward the majority class are ineffective due to the relative severity of misclassifying rare events. This paper proposes a novel evolutionary cluster-based oversampling ensemble framework, which combines a novel cluster-based synthetic data generation method with an evolutionary algorithm (EA) to create an ensemble. The proposed synthetic data generation method is based on contemporary ideas of identifying oversampling regions using clusters...
June 21, 2016: IEEE Transactions on Cybernetics
Zhiwen Yu, Xianjun Zhu, Hau-San Wong, Jane You, Jun Zhang, Guoqiang Han
The objective of cluster structure ensemble is to find a unified cluster structure from multiple cluster structures obtained from different datasets. Unfortunately, not all the cluster structures contribute to the unified cluster structure. This paper investigates the problem of how to select the suitable cluster structures in the ensemble which will be summarized to a more representative cluster structure. Specifically, the cluster structure is first represented by a mixture of Gaussian distributions, the parameters of which are estimated using the expectation-maximization algorithm...
June 1, 2016: IEEE Transactions on Cybernetics
Birendra Mishra, Laura Ortiz, Ulrike Luderer
STUDY QUESTION: Do charged iron particles, components of space radiation, cause premature ovarian failure? SUMMARY ANSWER: Exposure to charged iron particles causes ovarian DNA damage, oxidative damage and apoptosis, resulting in premature ovarian failure. WHAT IS KNOWN ALREADY: The ovary is very sensitive to follicle destruction by low linear energy transfer (LET) radiation, such as X-rays and γ-rays. However, it is completely unknown whether high-LET radiation, such as charged iron particles, also destroys ovarian follicles...
August 2016: Human Reproduction
Megan Boysen Osborn, James Mattson, Justin Yanuck, Craig Anderson, Ara Tekian, John Christian Fox, Ilene B Harris
PURPOSE: To examine the variability among medical schools in ranking systems used in medical student performance evaluations (MSPEs). METHOD: The authors reviewed MSPEs from U.S. MD-granting medical schools received by the University of California, Irvine emergency medicine and internal medicine residency programs during 2012-2013 and 2014-2015. They recorded whether the school used a ranking system, the type of ranking system used, the size and description of student categories, the location of the ranking statement and category legend, and whether nonranking schools used language suggestive of rank...
April 12, 2016: Academic Medicine: Journal of the Association of American Medical Colleges
Jennifer Kumar, Ngoc-Tram Gia Tran, John Schomberg, Elani Streja, Kamyar Kalantar-Zadeh, Madeleine Pahl
OBJECTIVE: The management of hyperparathyroidism in hemodialysis patients involves the administration of phosphate binders, vitamin D receptor activators, and calcimimetics. Intravenous paricalcitol has been preferred over oral calcitriol as it may cause less hypercalcemia and hyperphosphatemia. However, there is little data looking at the efficacy and tolerability of oral calcitriol in the calcimimetic era particularly in a real practice-based experience. The University of California, Irvine free-standing dialysis center converted from routine intravenous paricalcitol to oral calcitriol due to pharmacy purchasing preferences...
July 2016: Journal of Renal Nutrition
Alon Yehoshua, Michael Chancellor, Sandip Vasavada, Daniel C Malone, Edward P Armstrong, Manher Joshi, Karen Campbell, Riya Pulicharam
BACKGROUND: Overactive bladder (OAB) is a common medical condition with significant economic and humanistic burden. Inadequately managed OAB may exacerbate or result in comorbidities such as depression, falls, and urinary tract infections, which can further increase the burden to the health care system. Anticholinergics are often prescribed for management of OAB with urinary incontinence ("wet" OAB). However, research has shown that patient adherence and persistence to anticholinergic therapy is poor, with approximately 80% of patients ultimately failing their first prescribed anticholinergic medication within the first year...
April 2016: Journal of Managed Care & Specialty Pharmacy
Megan Boysen-Osborn, Craig L Anderson, Roman Navarro, Justin Yanuck, Suzanne Strom, Christopher E McCoy, Julie Youm, Mary Frances Ypma-Wong, Mark I Langdorf
PURPOSE: It aimed to find if written test results improved for advanced cardiac life support (ACLS) taught in flipped classroom/team-based Learning (FC/TBL) vs. lecture-based (LB) control in University of California-Irvine School of Medicine, USA. METHODS: Medical students took 2010 ACLS with FC/TBL (2015), compared to 3 classes in LB (2012-14) format. There were 27.5 hours of instruction for FC/TBL model (TBL 10.5, podcasts 9, small-group simulation 8 hours), and 20 (12 lecture, simulation 8 hours) in LB...
2016: Journal of Educational Evaluation for Health Professions
Hamilton Chen, Robert Kim, Danielle Perret, Justin Hata, Joseph Rinehart, Eric Chang
OBJECTIVE: To assess whether a combination of lecture and model simulation improves resident competency and comfort level with needle driving for interventional pain medicine procedures. DESIGN: Prospective, observational study. METHOD: Trainees who rotated through the University of California, Irvine, outpatient pain medicine clinic were recruited for the study. Subjects were given a brief lecture and completed a survey with questions regarding their level of comfort with interventional pain medicine procedures...
April 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Michael A Liu, Jannett Nguyen, Annie Nguyen, David B Kilgore
Complementary and alternative medicine (CAM) is widely used by adults in the USA. However, most physicians do not inquire about CAM use leading to missed opportunities to dialogue about wellness and detect harmful practices. In 2012, an integrative medicine (IM) consultation clinic alongside an optional IM Residency Track for family medicine residents was established at the University of California, Irvine Family Health Center in Santa Ana, CA. This study evaluated the impact of these programmes on physicians' CAM/IM knowledge and receptiveness...
November 2015: Education for Primary Care
Yan-Lin He, Yuan Xu, Zhi-Qiang Geng, Qun-Xiong Zhu
In this paper, a hybrid robust model based on an improved functional link neural network integrating with partial least square (IFLNN-PLS) is proposed. Firstly, an improved functional link neural network with small norm of expanded weights and high input-output correlation (SNEWHIOC-FLNN) was proposed for enhancing the generalization performance of FLNN. Unlike the traditional FLNN, the expanded variables of the original inputs are not directly used as the inputs in the proposed SNEWHIOC-FLNN model. The original inputs are attached to some small norm of expanded weights...
March 2016: ISA Transactions
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