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https://www.readbyqxmd.com/read/28185763/bariatric-surgery-attenuates-colitis-in-an-obese-murine-model
#1
Shiri Li, Alessio Vinci, Judith Behnsen, Chunmei Cheng, Stefan Jellbauer, Manuela Raffatellu, Kyle M Sousa, Robert Edwards, Ninh T Nguyen, Michael J Stamos, Alessio Pigazzi
BACKGROUND: Obesity and inflammatory bowel disease (IBD) represent chronic inflammatory conditions. Bariatric surgery improves some obesity-related co-morbidities, but the effects of bariatric surgery on IBD have not been well studied. OBJECTIVES: To examine if bariatric surgery may attenuate colitis in an obese murine model of IBD and study the mechanisms underlying the postsurgical amelioration of intestinal inflammation. SETTING: University of California Irvine, Department of Surgery and Microbiology laboratories...
December 20, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28113355/progressive-semisupervised-learning-of-multiple-classifiers
#2
Zhiwen Yu, Ye Lu, Jun Zhang, Jane You, Hau-San Wong, Yide Wang, Guoqiang Han
Semisupervised learning methods are often adopted to handle datasets with very small number of labeled samples. However, conventional semisupervised ensemble learning approaches have two limitations: 1) most of them cannot obtain satisfactory results on high dimensional datasets with limited labels and 2) they usually do not consider how to use an optimization process to enlarge the training set. In this paper, we propose the progressive semisupervised ensemble learning approach (PSEMISEL) to address the above limitations and handle datasets with very small number of labeled samples...
January 19, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28101267/bioart-and-bildung-wetware-art-agency-animation-an-exhibition-as-case-study
#3
Charissa N Terranova
Recent events in the field of biology have further unfixed the definition of life. The negotiability of "life" is at the center of the exhibition "Wetware: Art, Agency, Animation" at the Beall Center for Art + Technology at the University of California, Irvine. The exhibition includes art by nine international artists working in the avant-garde area of contemporary art called "bioart." This article is devoted to the unique educational space opened through the practice of bioart, focusing on how the exhibition brings the scientific question "What is life?" to a public audience...
December 2016: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/27956294/nonlinear-optical-corneal-collagen-crosslinking-of-ex%C3%A2-vivo-rabbit-eyes
#4
Samantha M Bradford, Donald J Brown, Tibor Juhasz, Eric Mikula, James V Jester
PURPOSE: To determine whether riboflavin-induced collagen crosslinking (CXL) could be precisely achieved in the corneal stroma of ex vivo rabbit eyes using nonlinear optical excitation with a low numerical aperture lens and enlarged focal volume. SETTING: Gavin Herbert Eye Institute, University of California Irvine, Irvine, California, USA. DESIGN: Experimental study. METHODS: The corneal epithelium was removed and the corneas were soaked in 0...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27955983/what-predicts-performance-a-multicenter-study-examining-the-association-between-resident-performance-rank-list-position-and-united-states-medical-licensing-examination-step-1-scores
#5
Jonathan G Wagner, Todd Schneberk, Marissa Zobrist, H Gene Hern, Jamie Jordan, Megan Boysen-Osborn, Michael Menchine
BACKGROUND: Each application cycle, emergency medicine (EM) residency programs attempt to predict which applicants will be most successful in residency and rank them accordingly on their program's Rank Order List (ROL). OBJECTIVE: Determine if ROL position, participation in a medical student rotation at their respective program, or United States Medical Licensing Examination (USMLE) Step 1 rank within a class is predictive of residency performance. METHODS: All full-time EM faculty at Los Angeles County + University of Southern California (LAC + USC), Harbor-UCLA (Harbor), Alameda Health System-Highland (Highland), and the University of California-Irvine (UCI) ranked each resident in the classes of 2013 and 2014 at time of graduation...
March 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27918414/wearable-sensor-based-human-activity-recognition-method-with-multi-features-extracted-from-hilbert-huang-transform
#6
Huile Xu, Jinyi Liu, Haibo Hu, Yi Zhang
Wearable sensors-based human activity recognition introduces many useful applications and services in health care, rehabilitation training, elderly monitoring and many other areas of human interaction. Existing works in this field mainly focus on recognizing activities by using traditional features extracted from Fourier transform (FT) or wavelet transform (WT). However, these signal processing approaches are suitable for a linear signal but not for a nonlinear signal. In this paper, we investigate the characteristics of the Hilbert-Huang transform (HHT) for dealing with activity data with properties such as nonlinearity and non-stationarity...
December 2, 2016: Sensors
https://www.readbyqxmd.com/read/27777752/a-case-management-report-a-collaborative-perioperative-surgical-home-paradigm-and-the-reduction-of-total-joint-arthroplasty-readmissions
#7
Navid Alem, Joseph Rinehart, Brian Lee, Doug Merrill, Safa Sobhanie, Kyle Ahn, Ran Schwarzkopf, Maxime Cannesson, Zeev Kain
BACKGROUND: Efforts to mitigate costs while improving surgical care quality have received much scrutiny. This includes the challenging issue of readmission subsequent to hospital discharge. Initiatives attempting to preclude readmission after surgery require planned and unified efforts extending throughout the perioperative continuum. Patient optimization prior to discharge, enhanced disease monitoring, and seamless coordination of care between hospitals and community providers is integral to this process...
2016: Perioperative Medicine
https://www.readbyqxmd.com/read/27651977/lessons-from-ebola-sources-of-outbreak-information-and-the-associated-impact-on-uc-irvine-and-ohio-university-college-students
#8
Thrissia Koralek, Miryha G Runnerstrom, Brandon J Brown, Chukwuemeka Uchegbu, Tania B Basta
Objectives. We examined the role of outbreak information sources through four domains: knowledge, attitudes, beliefs, and stigma related to the 2014 Ebola virus disease (EVD) outbreak. Methods. We conducted an online survey of 797 undergraduates at the University of California, Irvine (UCI) and Ohio University (OU) during the peak of the outbreak. We calculated individual scores for domains and analyzed associations to demographic variables and news sources. Results. Knowledge of EVD was low and misinformation was prevalent...
2016: PLoS Currents
https://www.readbyqxmd.com/read/27633332/c-sats-assessing-surgical-skills-among-urology-residency-applicants
#9
Simone L Vernez, Victor Huynh, Kathryn Osann, Zhamshid Okhunov, Jaime Landman, Ralph V Clayman
BACKGROUND: We hypothesized that surgical skills assessment could aid in the selection process of medical student applicants to a surgical program. Recently, crowdsourcing has been shown to provide an accurate assessment of surgical skills at all levels of training. We compared expert and crowd assessment of surgical tasks performed by resident applicants during their interview day at the urology program at the University of California, Irvine. MATERIALS AND METHODS: Twenty-five resident interviewees performed four tasks: open square knot tying, laparoscopic peg transfer, robotic suturing, and skill task 8 on the LAP Mentor™ (Simbionix Ltd...
October 11, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27625710/discriminating-between-legitimate-and-predatory-open-access-journals-report-from-the-international-federation-for-emergency-medicine-research-committee
#10
REVIEW
Bhakti Hansoti, Mark I Langdorf, Linda S Murphy
INTRODUCTION: Open access (OA) medical publishing is growing rapidly. While subscription-based publishing does not charge the author, OA does. This opens the door for "predatory" publishers who take authors' money but provide no substantial peer review or indexing to truly disseminate research findings. Discriminating between predatory and legitimate OA publishers is difficult. METHODS: We searched a number of library indexing databases that were available to us through the University of California, Irvine Libraries for journals in the field of emergency medicine (EM)...
September 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27579266/patient-race-and-provider-predict-patient-satisfaction-following-post-mastectomy-breast-reconstruction
#11
Ashkaun Shaterian, Jessica Gandy, Shadi Lalezari, Sarah Smith, Keyianoosh Paydar
BACKGROUND: Post-mastectomy breast reconstruction is commonly performed in the United States with numerous options available to patients and providers. This study evaluated patient race and provider in prediction of patient satisfaction following post-mastectomy breast reconstruction. METHODS: The patient satisfaction for women who underwent post mastectomy breast reconstruction at University of California, Irvine Medical Center was evaluated between 2012 and 2014, randomly using Press Ganey Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) surveys...
May 2016: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27569686/association-of-maternal-prepregnancy-bmi-with-metabolomic-profile-across-gestation
#12
C Hellmuth, K L Lindsay, O Uhl, C Buss, P D Wadhwa, B Koletzko, S Entringer
BACKGROUND/OBJECTIVES: Elevated prepregnancy body mass index (pBMI) and excess gestational weight gain (GWG) constitute important prenatal exposures that may program adiposity and disease risk in offspring. The objective of this study is to investigate the influence of pBMI and GWG on the maternal metabolomic profile across pregnancy, and to identify associations with birth weight. SUBJECTS/METHODS: This is a longitudinal prospective study of 167 nondiabetic women carrying a singleton pregnancy...
January 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27527559/predicting-responses-to-neoadjuvant-chemotherapy-in-breast-cancer-acrin-6691-trial-of-diffuse-optical-spectroscopic-imaging
#13
Bruce J Tromberg, Zheng Zhang, Anaïs Leproux, Thomas D O'Sullivan, Albert E Cerussi, Philip M Carpenter, Rita S Mehta, Darren Roblyer, Wei Yang, Keith D Paulsen, Brian W Pogue, Shudong Jiang, Peter A Kaufman, Arjun G Yodh, So Hyun Chung, Mitchell Schnall, Bradley S Snyder, Nola Hylton, David A Boas, Stefan A Carp, Steven J Isakoff, David Mankoff
The prospective multicenter ACRIN 6691 trial was designed to evaluate whether changes from baseline to mid-therapy in a diffuse optical spectroscopic imaging (DOSI)-derived imaging endpoint, the tissue optical index (TOI), predict pathologic complete response (pCR) in women undergoing breast cancer neoadjuvant chemotherapy (NAC). DOSI instruments were constructed at the University of California, Irvine (Irvine, CA), and delivered to six institutions where 60 subjects with newly diagnosed breast tumors (at least 2 cm in the longest dimension) were enrolled over a 2-year period...
October 15, 2016: Cancer Research
https://www.readbyqxmd.com/read/27502809/use-and-interest-in-complementary-and-alternative-medicine-among-college-students-seeking-healthcare-at-a-university-campus-student-health-center
#14
Jannett Nguyen, Michael A Liu, Rohini J Patel, Keli Tahara, Annie L Nguyen
BACKGROUND: There is growing data on complementary and alternative medicine (CAM) preferences among college students. While several studies have focused on undergraduate students, there is limited data on graduate students. MATERIALS AND METHODS: Cross sectional analysis of undergraduate and graduate students seeking medical care at the University of California Irvine's Student Health Center (SHC). The survey assessed previous CAM use and preferences for future CAM use and education...
August 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27444562/random-bits-forest-a-strong-classifier-regressor-for-big-data
#15
Yi Wang, Yi Li, Weilin Pu, Kathryn Wen, Yin Yao Shugart, Momiao Xiong, Li Jin
Efficiency, memory consumption, and robustness are common problems with many popular methods for data analysis. As a solution, we present Random Bits Forest (RBF), a classification and regression algorithm that integrates neural networks (for depth), boosting (for width), and random forests (for prediction accuracy). Through a gradient boosting scheme, it first generates and selects ~10,000 small, 3-layer random neural networks. These networks are then fed into a modified random forest algorithm to obtain predictions...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27441392/prevalence-severity-exposures-and-treatment-patterns-of-tinnitus-in-the-united-states
#16
Jay M Bhatt, Harrison W Lin, Neil Bhattacharyya
Importance: Tinnitus is a common problem for millions of individuals and can cause substantial negative effects on their quality of life. A large epidemiologic study of tinnitus and its management patterns in the US adult population is lacking. Objectives: To quantify the epidemiologic features and effect of tinnitus and to analyze the management of tinnitus in the United States relative to the 2014 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) clinical practice guidelines...
October 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27337735/evolutionary-cluster-based-synthetic-oversampling-ensemble-eco-ensemble-for-imbalance-learning
#17
Pin Lim, Chi Keong Goh, Kay Chen Tan
Class imbalance problems, where the number of samples in each class is unequal, is prevalent in numerous real world machine learning applications. Traditional methods which are biased toward the majority class are ineffective due to the relative severity of misclassifying rare events. This paper proposes a novel evolutionary cluster-based oversampling ensemble framework, which combines a novel cluster-based synthetic data generation method with an evolutionary algorithm (EA) to create an ensemble. The proposed synthetic data generation method is based on contemporary ideas of identifying oversampling regions using clusters...
June 21, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27254876/distribution-based-cluster-structure-selection
#18
Zhiwen Yu, Xianjun Zhu, Hau-San Wong, Jane You, Jun Zhang, Guoqiang Han
The objective of cluster structure ensemble is to find a unified cluster structure from multiple cluster structures obtained from different datasets. Unfortunately, not all the cluster structures contribute to the unified cluster structure. This paper investigates the problem of how to select the suitable cluster structures in the ensemble which will be summarized to a more representative cluster structure. Specifically, the cluster structure is first represented by a mixture of Gaussian distributions, the parameters of which are estimated using the expectation-maximization algorithm...
June 1, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27251203/charged-iron-particles-components-of-space-radiation-destroy-ovarian-follicles
#19
Birendra Mishra, Laura Ortiz, Ulrike Luderer
STUDY QUESTION: Do charged iron particles, components of space radiation, cause premature ovarian failure? SUMMARY ANSWER: Exposure to charged iron particles causes ovarian DNA damage, oxidative damage and apoptosis, resulting in premature ovarian failure. WHAT IS KNOWN ALREADY: The ovary is very sensitive to follicle destruction by low linear energy transfer (LET) radiation, such as X-rays and γ-rays. However, it is completely unknown whether high-LET radiation, such as charged iron particles, also destroys ovarian follicles...
August 2016: Human Reproduction
https://www.readbyqxmd.com/read/27075499/ranking-practice-variability-in-the-medical-student-performance-evaluation-so-bad-it-s-good
#20
Megan Boysen Osborn, James Mattson, Justin Yanuck, Craig Anderson, Ara Tekian, John Christian Fox, Ilene B Harris
PURPOSE: To examine the variability among medical schools in ranking systems used in medical student performance evaluations (MSPEs). METHOD: The authors reviewed MSPEs from U.S. MD-granting medical schools received by the University of California, Irvine emergency medicine and internal medicine residency programs during 2012-2013 and 2014-2015. They recorded whether the school used a ranking system, the type of ranking system used, the size and description of student categories, the location of the ranking statement and category legend, and whether nonranking schools used language suggestive of rank...
November 2016: Academic Medicine: Journal of the Association of American Medical Colleges
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