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https://www.readbyqxmd.com/read/29778923/quantitative-proteomic-profiling-indicates-the-difference-in-reproductive-efficiency-between-meishan-and-duroc-boar-spermatozoa
#1
Li Xinhong, Linqing Zhen, Jieli Fu, Lirui Wang, Qiangzhen Yang, Peifei Li, Yuhua Li
The reproductive efficiency of Meishan pigs is higher than that of Duroc pigs, but the underlying molecular mechanism for this disparity remains unclear. No systematic quantitative proteomics studies, comparing global proteins in Meishan and Duroc boar spermatozoa have been reported. Therefore, we applied iTRAQ labeling coupled with mass spectrometry, and analyzed the differences in proteins between Meishan and Duroc sperm. In the present study, a total of 1597 proteins were quantified. Of these proteins, 190 showed statistically significant fold changes between Meishan and Duroc spermatozoa...
April 30, 2018: Theriogenology
https://www.readbyqxmd.com/read/29778855/myocardial-strain-in-prediction-of-outcomes-after-surgery-for-severe-mitral-regurgitation
#2
Hyue Mee Kim, Goo-Yeong Cho, In-Chang Hwang, Hong-Mi Choi, Jun-Bean Park, Yeonyee E Yoon, Hyung-Kwan Kim
OBJECTIVES: We investigated whether global longitudinal strain (GLS) is a better predictor of clinical events after surgery for mitral regurgitation (MR) than conventional parameters. BACKGROUND: The optimal timing for surgery is guided by left ventricular (LV) dimension or left ventricular ejection fraction (LVEF), even though normal LVEF can mask depressed LV systolic function in severe mitral MR. METHODS: From 2006 to 2016, 506 patients (age 58...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29778723/paleocene-eocene-and-plio-pleistocene-sea-level-changes-as-species-pumps-in-southeast-asia-evidence-from-althepus-spiders
#3
Fengyuan Li, Shuqiang Li
Sea-level change has been viewed as a primary driver in the formation of biodiversity. Early studies confirmed that Plio-Pleistocene sea-level changes led to the isolation and subsequent genetic differentiation of Southeast (SE) Asian organisms over short geological timescales. However, long-time consequences of sea-level fluctuations remain unclear. Herein, we analyze the evolutionary history of Althepus (spiders) whose distribution encompasses Indo-Burma and the Sunda shelf islands to understand how sea-level changes over shallow and deep timescales effected their history...
May 17, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29778686/methane-correction-factors-for-estimating-emissions-from-aerobic-wastewater-treatment-facilities-based-on-field-data-in-mexico-and-on-literature-review
#4
A Noyola, M G Paredes, L P Güereca, L T Molina, M Zavala
Wastewater treatment (WWT) may be an important source of methane (CH4 ), a greenhouse gas with significant global warming potential. Sources of CH4 emissions from WWT facilities can be found in the water and in the sludge process lines. Among the methodologies for estimating CH4 emissions inventories from WWT, the more adopted are the guidelines of the Intergovernmental Panel on Climate Change (IPCC), which recommends default emission factors (Tier 1) depending on WWT systems. Recent published results show that well managed treatment facilities may emit CH4 , due to dissolved CH4 in the influent wastewater; in addition, biological nutrient removal also will produce this gas in the anaerobic (or anoxic) steps...
May 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29778490/the-molecular-allergology-of-subtropical-grass-pollen
#5
Thina Kailaivasan, Janet M Davies
Grass pollens are amongst the most important aeroallergen sources world-wide triggering allergic rhinoconjunctivitis and asthma in sensitised patients. Much of what we know about the allergen components of grasses is informed by research on pollen of temperate (Pooideae) species that are abundant in the temperate climate zones. However, climate changes are altering the biogeographical distribution as well as timing and allergenicity of grass pollens. This provides an impetus for better understanding of the contribution of subtropical subfamilies of grasses to pollen allergy globally...
May 16, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29778462/altered-mitochondrial-acetylation-profiles-in-a-kainic-acid-model-of-temporal-lobe-epilepsy
#6
Lindsey B Gano, Li-Ping Liang, Kristen Ryan, Cole R Michel, Joe Gomez, Athanassios Vassilopoulos, Nichole Reisdorph, Kristofer S Fritz, Manisha Patel
Impaired bioenergetics and oxidative damage in the mitochondria are implicated in the etiology of temporal lobe epilepsy, and hyperacetylation of mitochondrial proteins has recently emerged as a critical negative regulator of mitochondrial functions. However, the roles of mitochondrial acetylation and activity of the primary mitochondrial deacetylase, SIRT3, have not been explored in acquired epilepsy. We investigated changes in mitochondrial acetylation and SIRT3 activity in the development of chronic epilepsy in the kainic acid rat model of TLE...
May 17, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29778275/quantifying-the-effects-of-16p11-2-copy-number-variants-on-brain-structure-a-multisite-genetic-first-study
#7
Sandra Martin-Brevet, Borja Rodríguez-Herreros, Jared A Nielsen, Clara Moreau, Claudia Modenato, Anne M Maillard, Aurélie Pain, Sonia Richetin, Aia E Jønch, Abid Y Qureshi, Nicole R Zürcher, Philippe Conus, Wendy K Chung, Elliott H Sherr, John E Spiro, Ferath Kherif, Jacques S Beckmann, Nouchine Hadjikhani, Alexandre Reymond, Randy L Buckner, Bogdan Draganski, Sébastien Jacquemont
BACKGROUND: 16p11.2 breakpoint 4 to 5 copy number variants (CNVs) increase the risk for developing autism spectrum disorder, schizophrenia, and language and cognitive impairment. In this multisite study, we aimed to quantify the effect of 16p11.2 CNVs on brain structure. METHODS: Using voxel- and surface-based brain morphometric methods, we analyzed structural magnetic resonance imaging collected at seven sites from 78 individuals with a deletion, 71 individuals with a duplication, and 212 individuals without a CNV...
March 27, 2018: Biological Psychiatry
https://www.readbyqxmd.com/read/29777953/ultrasound-guided-application-of-percutaneous-electrolysis-as-an-adjunct-to-exercise-and-manual-therapy-for-subacromial-pain-syndrome-a-randomized-clinical-trial
#8
Lorena de-Miguel-Valtierra, Jaime Salom-Moreno, César Fernández-de-Las-Peñas, Joshua A Cleland, José L Arias-Buría
This randomized clinical trial compared the effects of adding US-guided percutaneous electrolysis into a program consisting of manual therapy and exercise on pain, related-disability, function and pressure sensitivity in subacromial pain syndrome. Fifty patients with subacromial pain syndrome were randomized into manual therapy and exercise or percutaneous electrolysis group. All patients received the same manual therapy and exercise program, one session per week for 5 consecutive weeks. Patients assigned to the electrolysis group also received the application of percutaneous electrolysis at each session...
May 16, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29777938/austrian-firearm-legislation-and-its-effects-on-suicide-and-homicide-mortality-a-natural-quasi-experiment-amidst-the-global-economic-crisis
#9
Daniel König, Patrick Swoboda, Robert J Cramer, Christoph Krall, Vita Postuvan, Nestor D Kapusta
BACKGROUND: Restriction of access to suicide methods has been shown to effectively reduce suicide mortality rates. AIMS: To examine how the global economic crisis of 2008 and the firearm legislation reform of 1997 affected suicide and homicide mortality rate within Austria. METHODS: Official data for the years 1985-2016 for firearm certificates, suicide, homicide, unemployment rates and alcohol consumption were examined using auto regressive error and Poisson regression models...
May 16, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29777877/multi-walled-carbon-nanotubeinduced-inhalation-toxicity-recognizing-nano-bis-demethoxy-curcumin-analog-as-an-ameliorating-candidate
#10
Arul Prakash Francis, Thiyagarajan Devasena, Selvam Ganapathy, Venkata Rajsekhar Palla, Prakhya Balakrishna Murthy, Sundara Ramaprabhu
Human beings and ecosystems are being possibly exposed to CNTs, as there is a rise in global production rate of carbon nanotubes (CNTs). This may affect the health of humans and increases the environmental risk. We have already reported the pulmonary toxicity due to the inhalation of MWCNTs. We claim that a compound with anti-inflammatory and antioxidant activity may ameliorate the CNT-induced toxic effect. With this view, we have investigated the ameliorative effect of intravenously-administered nano bis-demethoxy curcumin analog (NBDMCA) against MWCNTs-induced inhalation toxicity by examining the lung histopathology for inflammatory cell dynamics, pulmonary remodeling and estimating the inflammatory biomarkers in the broncho-alveolar lavage fluid...
May 16, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29777824/brain-network-segregation-and-integration-during-an-epoch-related-working-memory-fmri-experiment
#11
Peter Fransson, Björn C Schiffler, William Hedley Thompson
The characterization of brain subnetwork segregation and integration has previously focused on changes that are detectable at the level of entire sessions or epochs of imaging data. In this study, we applied time-varying functional connectivity analysis together with temporal network theory to calculate point-by-point estimates in subnetwork segregation and integration during an epoch-based (2-back, 0-back, baseline) working memory fMRI experiment as well as during resting-state. This approach allowed us to follow task-related changes in subnetwork segregation and integration at a high temporal resolution...
May 16, 2018: NeuroImage
https://www.readbyqxmd.com/read/29777822/effects-of-global-signal-regression-and-subtraction-methods-on-resting-state-functional-connectivity-using-arterial-spin-labeling-data
#12
João Paulo Santos Silva, Luciana da Mata Mônaco, André Monteiro Paschoal, Ícaro Agenor Ferreira de Oliveira, Renata Ferranti Leoni
BACKGROUND: Arterial spin labeling (ASL) is an established magnetic resonance imaging (MRI) technique that is finding broader applications in functional studies of the healthy and diseased brain. To promote improvement in cerebral blood flow (CBF) signal specificity, many algorithms and imaging procedures, such as subtraction methods, were proposed to eliminate or, at least, minimize noise sources. Therefore, this study addressed the main considerations of how CBF functional connectivity (FC) is changed, regarding resting brain network (RBN) identification and correlations between regions of interest (ROI), by different subtraction methods and removal of residual motion artifacts and global signal fluctuations (RMAGSF)...
May 16, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29777788/modified-transanosphincteric-york-mason-repair-of-non-radiated-rectourinary-fistulae-patient-reported-fecal-continence-outcomes
#13
Maxim J McKibben, Joceline S Fuchs, Alexander T Rozanski, Jeremy M Scott, Craig Olson, Farshid Araghizadeh, Allen F Morey
OBJECTIVES: To review our experience with the modified York Mason (MYM) procedure in treatment of rectourinary fistulae (RUF), and to assess fecal continence using patient reported measures. METHODS: Retrospective review was performed for patients who underwent MYM repair of non-radiated RUF with gluteal free fat graft from 2008 to 2016 at a single institution. Success was defined as resolution of fistula without need for further surgery. The Cleveland Clinic-Florida Wexner Fecal Incontinence Score (CCFFIS) and Patient Global Impression of Improvement (PGI-I) surveys were administered by phone...
May 16, 2018: Urology
https://www.readbyqxmd.com/read/29777644/closing-the-gap-between-people-and-programs-lessons-from-implementation-of-social-accountability-for-family-planning-and-reproductive-health-in-uganda
#14
Vicky Boydell, Stella Neema, Kelsey Wright, Karen Hardee
Globally, women's access to modern contraception can be attributed to poor service conditions and care. Growing evidence from across the health sector has found that social accountability approaches have the potential to improve the quality of care and therefore the utilization of health services, little of this evidence relates to family planning and reproductive health programs. This paper therefore assessed the results of retrospective implementation research into a five-year social accountability project in Uganda that focused on family planning and reproductive health...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29777621/serum-high-density-lipoprotein-cholesterol-is-a-protective-predictor-of-executive-function-in-older-patients-with-diabetes-mellitus
#15
Yue Sun, Jenny Lee, Ronald C Ma, Timothy Kwok
INTRODUCTION: Older people with diabetes mellitus (DM) are at high risk for cognitive impairment or dementia. The clinical predictors for cognitive decline in older people with DM were elucidated. METHODS: This was a secondary analysis of a vitamin B12 intervention trial in older people with DM. 271 non-demented subjects were followed up at nine months interval for 27 months. We explored the association between baseline clinical features with changes in cognitive measures (clinical dementia rating scale, neuropsychological test battery including executive function z scores, psychomotor speed z scores and memory z scores)...
May 19, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29777620/vegetation-growth-enhancement-in-urban-environments-of-the-conterminous-united-states
#16
Wenxiao Jia, Shuqing Zhao, Shuguang Liu
Cities are natural laboratories for studying vegetation responses to global environmental changes because of their climate, atmospheric, and biogeochemical conditions. However, few holistic studies have been conducted on the impact of urbanization on vegetation growth. We decomposed the overall impacts of urbanization on vegetation growth into direct (replacement of original land surfaces by impervious built-up) and indirect (urban environments) components, using a conceptual framework and remotely-sensed data for 377 metropolitan statistical areas (MSAs) in the conterminous United States (CONUS) in 2001, 2006, and 2011...
May 19, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29777281/right-ventricular-systolic-function-parameters-in-hypoplastic-left-heart-syndrome
#17
S Javed Zaidi, Jamie Penk, Vivian W Cui, Supaluck Kanjanauthai, David A Roberson
Assessment of the systolic function of the right ventricle (RV) in patients with hypoplastic left heart syndrome (HLHS) is important. The asymmetric shape and heavy trabeculations make accurate assessment of RV systolic function challenging. Novel measures of RV function could be helpful in distinguishing reduced versus preserved function in HLHS and may also be worse in HLHS with preserved function compared to normal controls. These novel methods offer promise, but research and clinical applicability is hindered as no cut-off values for normal function have been established...
May 18, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29777196/single-measurement-detection-of-individual-cell-ionic-oscillations-using-an-n-type-semiconductor-electrolyte-interface
#18
Mariusz Pietruszka, Monika Olszewska, Lukasz Machura, Edward Rówiński
Pollen tubes are used as models in studies on the type of tip-growth in plants. They are an example of polarised and rapid growth because pollen tubes are able to quickly invade the flower pistil in order to accomplish fertilisation. How different ionic fluxes are perceived, processed or generated in the pollen tube is still not satisfactorily understood. In order to measure the H+ , K+ , Ca2+ and Cl- fluxes of a single pollen tube, we developed an Electrical Lab on a Photovoltaic-Chip (ELoPvC) on which the evolving cell was immersed in an electrolyte of a germination medium...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776753/genetic-and-antigenic-relationship-of-foot-and-mouth-disease-virus-serotype-o-isolates-with-the-vaccine-strain-o1-bfs
#19
Wanhong Xu, Zhidong Zhang, Charles Nfon, Ming Yang
Foot-and-mouth disease serotype O viruses (FMDV/O) are responsible for the most outbreaks in FMD endemic countries. O1/BFS is one of the recommended FMD/O vaccine strains by World Reference Laboratory for FMD. In the current study, FMDV/O1 BFS vaccine strain and serotype O field isolates (45) were analyzed phylogenetically and antigenically to gain more insight into the genetic and antigenic characteristics of the vaccine strain and field isolates. O1/BFS showed similarity with 89% of the field isolates using a virus neutralization test (VNT)...
May 15, 2018: Vaccine
https://www.readbyqxmd.com/read/29776414/glp-i-secretion-in-healthy-and-diabetic-wistar-rats-in-response-to-aqueous-extract-of-momordica-charantia
#20
Gulzar Ahmad Bhat, Haseeb A Khan, Abdullah S Alhomida, Poonam Sharma, Rambir Singh, Bilal Ahmad Paray
BACKGROUND: Diabetes mellitus is one of the major global health disorders increasing at an alarming rate in both developed and developing countries. The objective of this study was to assess the effect of aqueous extract of Momordica charantia (AEMC) on fasting blood glucose (FBG), tissue glycogen, glycosylated haemoglobin, plasma concentrations of insulin and GLP-1 hormone (glucagon-like peptide 1) in healthy and diabetic wistar rats. METHODS: Male Wistar rats (both normal and diabetic) were treated with AEMC by gavaging (300 mg/kg body wt/day for 28 days)...
May 18, 2018: BMC Complementary and Alternative Medicine
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