David E Kandzari, Michael A Weber, Atul Pathak, James P Zidar, Manish Saxena, Shukri W David, Roland E Schmieder, Adam J Janas, Christoph Langer, Alexandre Persu, Farrell O Mendelsohn, Koen Ameloot, Malcolm Foster Iii, Tim A Fischell, Helen Parise, Felix Mahfoud
BACKGROUND: Renal denervation (RDN) has demonstrated clinically relevant reductions in blood pressure among individuals with uncontrolled hypertension despite lifestyle intervention and medications. The safety and effectiveness of alcohol-mediated RDN has not been formally studied in this indication. METHODS: TARGET BP I is a prospective, international, sham-controlled, randomized, patient- and assessor-blinded trial investigating the safety and efficacy of alcohol-mediated RDN...
April 8, 2024: Circulation