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Bitch hormones

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https://www.readbyqxmd.com/read/28583599/serum-concentration-dynamic-of-energy-homeostasis-hormones-leptin-insulin-thyroid-hormones-and-cortisol-throughout-canine-pregnancy-and-lactation
#1
L Cardinali, A Troisi, J P Verstegen, L Menchetti, A Elad Ngonput, C Boiti, S Canello, R Zelli, A Polisca
Pregnancy and lactation represent critical periods of canine reproductive life and different hormones are required to maintain homeostasis and the correct energy requirements. The aim of this study was to evaluate leptin, insulin, triiodotyronine (T3), thyroxin (T4) and cortisol serum concentrations to better describe the canine maternal energy metabolism. Twelve Bloodhound bitches that had at least one litter and were considered to be healthy submitted blood samples every 15 days starting from day 0 (ovulation) throughout pregnancy up to the end of lactation (day 120)...
July 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28466954/-downregulation-of-lh-in-the-bitch-after-application-of-the-gnrh-agonist-buserelin-as-a-slow-release-implant
#2
Andrea Piepenbrink, Klaus Failing, Anja Riesenbeck, Peter Schmid, Bernd Hoffmann
OBJECTIVES: Demonstration of downregulation of luteinizing hormone (LH) using the gonadotropin-releasing hormone (GnRH)-agonist buserelin as the active ingredient in the form of a slow-release implant. MATERIAL AND METHODS: To eliminate any negative feedback mechanisms of endogenous sex steroids, nine bitches were ovariohysterectomized prior to treatment. The applied drug was the slow-release implant Profact Depot(®) with the active ingredient buserelin; dosages were 3...
May 3, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28451590/molecular-signaling-of-progesterone-growth-hormone-wnt-and-her-in-mammary-glands-of-dogs-rodents-and-humans-new-treatment-target-identification
#3
REVIEW
Elpetra P M Timmermans-Sprang, Ana Gracanin, Jan A Mol
Mammary tumors are the most common form of neoplasia in the bitch. Female dogs are protected when they are spayed before the first estrus cycle, but this effect readily disappears and is already absent when dogs are spayed after the second heat. As the ovaries are removed during spaying, ovarian steroids are assumed to play an essential role in tumor development. The sensitivity toward tumor development is already present during early life, which may be caused by early mutations in stem cells during the first estrus cycles...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28317612/hormonal-electrolytic-and-electrocardiographic-evaluations-in-bitches-with-eutocia-and-dystocia
#4
Carla Regina Barbieri Simões, Flávia Gardilin Vassalo, Maria Lúcia Gomes Lourenço, Fabiana Ferreira de Souza, Eunice Oba, Mateus José Sudano, Nereu Carlos Prestes
The objective of the study was to assess clinical alterations, electrocardiographic, hematological, biochemical, hemogasometric, electrolytic, and hormone plasma concentrations in bitches with eutocia and dystocia. Overall, 28 bitches (dystocia, n = 22 and eutocia, n = 6) were assessed. The evaluations were performed at 2 time points, M1 (1 hour prepartum-eutocia group and cesarean or clinical intervention-dystocia group) and M2 (postpartum-eutocia or dystocia group and anesthetic recovery-dystocia group). The main clinical finding was the hypothermia (mean: 36...
December 2016: Topics in Companion Animal Medicine
https://www.readbyqxmd.com/read/28043343/expression-of-oxytocin-progesterone-and-estrogen-receptors-in-the-reproductive-tract-of-bitches-with-pyometra
#5
N Prapaiwan, S Manee-In, E Olanratmanee, S Srisuwatanasagul
Canine pyometra is considered a serious and life-threatening condition. Due to the relationship among sex steroid hormones, oxytocin receptor (OTR) expression, and canine pyometra pathogenesis, this study aimed to investigate the expression of oxytocin, progesterone, and estrogen receptors in the reproductive tissues of canines with pyometra by real-time PCR and immunohistochemistry. A total of 27 pyometra bitches were classified into open- and closed-cervix pyometra groups based on the presence of vaginal discharge...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/27757997/determination-of-the-normal-reference-interval-for-anti-m%C3%A3-llerian-hormone-amh-in-bitches-and-use-of-amh-as-a-potential-predictor-of-litter-size
#6
F K Hollinshead, C Walker, D W Hanlon
Anti-Müllerian hormone (AMH) is a reliable endocrine marker of ovarian reserve in many species with extensive literature in both humans and cattle. However, there are no known hormonal predictors of ovarian reserve and potential reproductive performance in the bitch. A prospective cohort study was performed involving 155 intact bitches of various ages (range 1.2-7.6 years) and breeds that were presented for routine breeding management over a one-year period. All bitches were artificially inseminated with frozen or fresh semen using the transcervical insemination (TCI) technique...
October 18, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27670935/determination-of-gestational-time-and-prediction-of-parturition-in-dogs-and-cats-an-update
#7
M Beccaglia, S Alonge, C Trovo', G C Luvoni
Accurate prediction of delivery date in canine and feline allows a better management of parturition, reducing the loss of neonates. This review evaluates the most common methods adopted to accurately predict the day of delivery: determination of ovulation and hormonal assays, first appearance of embryonic/foetal structures using ultrasound or radiography, echographic measurement of extra-foetal and foetal structures, or evaluation of foetal flux and heart rate. Determination of ovulation and hormonal assays at the time of breeding and close to pregnancy term is widely used to predict parturition in dogs (Concannon et al...
September 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27570051/does-serum-anti-m%C3%A3-llerian-hormone-levels-always-discriminate-presence-of-the-ovaries-in-adult-bitches-comparison-of-two-elisa-kits
#8
I Pir Yagci, M Pekcan, I M Polat, H Kalender, H C Macun
Anti-Müllerian hormone (AMH) is produced in the ovary, and thus, it is an excellent marker of follicle pool in females. Current interest is the clinical use of this parameter as a biomarker to assess presence or absence of an intact ovary and to diagnose ovarian remnant syndrome (ORS) following incomplete ovariohysterectomy (OHE) in bitches. The aim of this study was to evaluate serum AMH concentrations in bitches (n = 34) before and after OHE using two different commercial ELISA kits, one of which is based on detecting human AMH and the other is based on detecting human AMH and the other specified for canine AMH...
December 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27270387/the-in-vitro-effect-of-prolactin-on-the-growth-motility-and-expression-of-prolactin-receptors-in-larvae-of-toxocara-canis
#9
L E Chávez-Güitrón, J Morales-Montor, M A Muñoz-Guzmán, K E Nava-Castro, H Ramírez-Álvarez, N A Moreno-Méndoza, R Hernández-Cervantes, F Alba-Hurtado
The in vitro effect of prolactin (PRL) on the growth and motility of Toxocara canis larvae was assessed. Additionally, the expression and location of prolactin receptors (PRL-Rs) were determined in the larvae. Larvae of T. canis were incubated with different concentrations of PRL for different periods of time. The stimulated larvae accelerated their enlargement and increased their motility. The mean percentage of PRL-R+ cells in non-stimulated larvae, measured by flow cytometry was 7.3±0.3%. Compared with non-stimulated larvae, the mean fluorescence intensity (p<0...
July 15, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/26733120/thyroxin-and-progesterone-concentrations-in-pregnant-nonpregnant-bitches-and-bitches-during-abortion
#10
Julianna Thuróczy, Linda Müller, Eszter Kollár, Lajos Balogh
Serum progesterone and thyroxin concentrations were measured weekly until 61 to 62 days after ovulation in 24 pregnant bitches and in the control group of nine nonpregnant bitches in the luteal phase. Fourteen of the 24 dogs had a normal pregnancy and parturition. Ten of the 24 dogs showed mucinous or colored vaginal discharge, decreased appetite, or lethargy. These initial signs of abortion or fetal resorption were noted during the fourth week of pregnancy, and the process occurred over the next 2 weeks. Progesterone and thyroxin concentrations were measured by quantitative ELISAs validated to dog serum...
April 1, 2016: Theriogenology
https://www.readbyqxmd.com/read/26099303/anti-m%C3%A3-llerian-hormone-as-a-diagnostic-tool-for-ovarian-remnant-syndrome-in-bitches
#11
Özge Turna Yilmaz, Tuğba Seval Fatma Toydemir, Ismail Kirsan, Zeynep Gunay Ucmak, Esra Caliskan Karacam
Ovariohysterectomy is a surgical procedure performed for sterilization. If part or all of an ovary remains after the surgical procedure, ovarian remnant syndrome (ORS) occurs. After revascularization of the remaining ovarian tissue, the sexual cycle of bitches and queens continues. The aim of this study was to investigate the usefulness of serum anti-Müllerian hormone (AMH) measurement for the diagnosis of ORS in bitches. Forty-six female dogs were divided into four groups: the prepubertal, unspayed, spayed, and ORS groups...
September 2015: Veterinary Research Communications
https://www.readbyqxmd.com/read/26041594/treatment-of-canine-pyometra-with-the-gonadotropin-releasing-hormone-antagonist-acyline-a-case-series
#12
Pablo R Batista, Paula G Blanco, Cristina Gobello
To describe the effect of the third-generation gonadotropin-releasing hormone antagonist acyline in the treatment of 4 diestrous bitches with the cystic endometrial hyperplasia-pyometra complex. The 4 bitches were treated with 330 μg/kg of subcutaneous acyline on day 0 and antibiotics, and followed up for 2 weeks. One closed-cervix case showed cervical dilatation 36 hours after treatment, and all the 4 animals showed resolution of clinical signs starting on day 3 posttreatment. Ultrasonographic uterine diameters and luminal contents decreased in the bitches having high progesterone serum concentrations before treatment but not in those with low levels...
March 2015: Topics in Companion Animal Medicine
https://www.readbyqxmd.com/read/25816198/changes-in-ovaries-and-uterus-after-aglepristone-administration-in-the-third-week-of-luteal-phase-of-non-pregnant-bitches
#13
Kamil Kacprzak, Piotr Jurka, Izabella Dolka, Michał Czopowicz, Anna Ruszczak, Anna Duszewska
OBJECTIVE: The mechanism of aglepristone action in the placentation time in the bitch remains unclear. The aim of this study was to describe the mechanism by which aglepristone influences ovaries and uterus and to measure the levels of steroid sex hormones in non-pregnant bitches. MATERIALS AND METHODS: Fourteen bitches assigned to a study (n=9) and control (n=5) group were given aglepristone and saline solution, respectively, on the 19th and 20th day after LH peak...
2015: PloS One
https://www.readbyqxmd.com/read/25714892/gene-expression-of-estrogen-and-oxytocin-receptors-in-the-uterus-of-pregnant-and-parturient-bitches
#14
G A L Veiga, M P Milazzotto, M Nichi, C F Lúcio, L C G Silva, D S R Angrimani, C I Vannucchi
In the canine species, the precise mechanisms of pregnancy maintenance and the initiation of parturition are not completely understood. The expression of genes encoding the receptors for estrogen (ERα mRNA) and oxytocin (OTR mRNA) was studied in the endometrium and myometrium during pregnancy and parturition in dogs. Real-time PCR was performed to quantify the levels of ERα mRNA and OTR mRNA in the uterus of bitches during early (up to 20 days of gestation), mid (20 to 40 days) and late pregnancy (41 to 60 days), and parturition (first stage of labor)...
April 2015: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/25510562/breed-specific-fetal-biometry-and-factors-affecting-the-prediction-of-whelping-date-in-the-german-shepherd-dog
#15
D Groppetti, F Vegetti, V Bronzo, A Pecile
To date many studies have been published about predicting parturition by ultrasonographic fetal measurements in the bitch. Given that accuracy in such prediction is a key point for clinicians and breeders, formulas to calculate the whelping date were mainly obtained from small and medium sized dogs, which means poor accuracy when applied to large or giant breeds. Based on the evidence that ethnicity significantly affects fetal biometry in humans, this study aimed at developing a breed-specific linear regression model for estimating parturition date in the German shepherd dog...
January 2015: Animal Reproduction Science
https://www.readbyqxmd.com/read/25472232/183-ultrasonographic-monitoring-of-canine-ovaries-clamped-at-subcutaneous-site-after-follicle-stimulating-hormone-treatment
#16
T Terazono, V V Luu, L T K Do, M Taniguchi, M Takagi, T Otoi
Follicle-stimulating hormone (FSH) alone can induce oestrus in bitches, but few reports describe oestrous induction by FSH because pregnant mare serum gonadotrophin (PMSG) has been more successful than FSH for oestrus induction. Real-time ultrasonography can show canine ovarian follicle development, but no method can determine or predict ovulation accurately. Moreover, the ovary location and size complicate imaging. Using ultrasonography, we investigated FSH treatment stimulation of canine ovary follicles, with clamping of the ovaries at a subcutaneous site...
December 2014: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/25459480/vaginal-impedometry-for-detection-of-optimal-breeding-time-in-bitches
#17
Lindsay H Bergeron, Stephanie G Nykamp, Brigitte A Brisson, Pavneesh Madan, William Sears, Cathy J Gartley
OBJECTIVE: To compare the efficacy of canine vaginal impedometry in identifying the preovulatory luteinizing hormone (LH) peak to that of currently used methods (serum progesterone concentration measurement, vaginal cytologic evaluation, and vaginoscopy). DESIGN: Prospective study. ANIMALS: 12 sexually intact female dogs. PROCEDURES: 12 mature postpubertal Beagle (n = 3), Beagle-cross (2), and hound-cross (7) bitches ranging from 7...
December 15, 2014: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/25331650/ovgp1-is-expressed-in-the-canine-oviduct-at-the-time-and-place-of-oocyte-maturation-and-fertilization
#18
Marie Saint-Dizier, Céline Marnier, Muhammad Zahid Tahir, Bénédicte Grimard, Sandra Thoumire, Sylvie Chastant-Maillard, Karine Reynaud
In the dog, oocyte maturation, fertilization, and early embryo development take place within the oviduct in the presence of increasing circulating progesterone (P4) levels. Expression of the oviduct-specific glycoprotein 1 (OVGP1), known in other species to be estrogen-dependent, was explored by real-time quantitative reverse-transcriptase PCR, Western blotting, and immunohistochemistry in oviducts from adult Beagle bitches during anestrus and at five specific time periods around ovulation: during pro-estrus before the luteinizing hormone (LH) peak (Pre-LH); after the LH peak and before ovulation (Pre-ov); and at Days 1, 4, and 7 after ovulation (n = 6 bitches per stage)...
November 2014: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/25311914/gnrh-analogue-treatment-on-lh-surge-day-0-followed-by-single-transvaginal-artificial-insemination-with-frozen-semen-on-day-5-in-bitches
#19
Tadatoshi Ohtaki, Yasuna Koga, Mamiko Ono, Gen Watanabe, Kazuyoshi Taya, Shigehisa Tsumagari
Reproductive parameters were evaluated in 19 and 14 estrous beagles that received 100 µg of gonadotropin-releasing hormone (GnRH) and saline treatment, respectively, on the day of luteinizing hormone (LH) surge (Day 0; estimated by serial progesterone assay) and balloon catheter-aided single transvaginal artificial insemination of frozen semen on Day 5. Although the conception rate and litter size were similar between the GnRH and saline groups, the concentration of LH peak was significantly higher in GnRH-treated bitches (P<0...
January 2015: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/25277434/clinical-use-of-deslorelin-gnrh-agonist-in-companion-animals-a-review
#20
REVIEW
X Lucas
Over the years, many contraceptive medications have been developed for companion animals, but many secondary adverse effects have limited their use. A major advancement was achieved with the use of gonadotropin-releasing hormone (GnRH) analogues, mainly GnRH agonists, which mimic the effects of native GnRH. The development of effective low-dose, slow-release implants with potent agonists such as deslorelin (Suprelorin®, Virbac) have allowed their use to become widespread in recent years, with many potential benefits in companion animals...
October 2014: Reproduction in Domestic Animals, Zuchthygiene
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