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https://www.readbyqxmd.com/read/28516169/hybrid-pixel-waveform-hpwf-enabled-cdte-detectors-for-small-animal-gamma-ray-imaging-applications
#1
A Groll, K Kim, H Bhatia, J C Zhang, J H Wang, Z M Shen, L Cai, J Dutta, Q Li, L J Meng
This paper presents the design and preliminary evaluation of small-pixel CdTe gamma ray detectors equipped with a hybrid pixel-waveform (HPWF) readout system for gamma ray imaging applications with additional discussion on CZT due to its similarity. The HPWF readout system utilizes a pixelated anode readout circuitry which is designed to only provide the pixel address. This readout circuitry works in coincidence with a high-speed digitizer to sample the cathode waveform which provides the energy, timing, and depth-of-interaction (DOI) information...
January 2017: IEEE Trans Radiat Plasma Med Sci
https://www.readbyqxmd.com/read/28512723/low-dose-dual-isotope-procedure-planed-for-myocardial-perfusion-czt-spect-and-assessed-through-a-head-to-head-comparison-with-a-conventional-single-isotope-protocol
#2
Laetitia Imbert, Véronique Roch, Charles Merlin, Wassila Djaballah, Florent Cachin, Mathieu Perrin, Marine Claudin, Antoine Verger, Henri Boutley, Gilles Karcher, Pierre-Yves Marie
PURPOSE OF THE REPORT: This study aimed at assessing an original low-dose dual-isotope procedure in which the abnormal stress Tc-99m Sestamibi SPECT is followed by rest Tl-201 SPECT, along with a head-to-head comparison with a single-isotope procedure. METHODS AND RESULTS: One hundred two patients, referred for a low-dose stress-SPECT with Sestamibi (123 ± 20 MBq) on a CZT camera and for whom a rest Sestamibi SPECT was warranted, had an additional Tl-201 rest-SPECT (52 ± 5 MBq) between stress and rest Sestamibi SPECT recordings...
May 16, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28462467/the-effect-of-ct-based-attenuation-correction-on-the-automatic-perfusion-score-of-myocardial-perfusion-imaging-using-a-dedicated-cardiac-solid-state-czt-spect-ct
#3
John A Kennedy, Yafim Brodov, Adam L Weinstein, Ora Israel, Alex Frenkel
BACKGROUND: Data regarding cardiac cadmium-zinc-telluride (CZT)-specific augmented databases and their impact on CT-based attenuation correction (AC) perfusion scores in myocardial perfusion imaging (MPI) were obtained on a multiple-pinhole CZT SPECT/CT. METHODS AND RESULTS: Summed stress (SSS) and rest scores (SRS) were measured using automated software in three independent patient groups: group 1 (n = 80) underwent MPI on both CZT and conventional sodium iodide (NaI) devices, group 2 (n = 80) with low coronary artery disease likelihood and normal MPI provided reference CZT databases; and group 3 (n = 152) served to compare AC and non-AC (NAC) scores on CZT...
May 1, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28450561/prognostic-value-of-myocardial-perfusion-imaging-with-czt-spect-camera-in-patients-suspected-for-coronary-artery-disease
#4
Elsemiek M Engbers, Jorik R Timmer, Mohamed Mouden, Siert Knollema, Pieter L Jager, Jan Paul Ottervanger
The prognostic value of myocardial perfusion imaging (MPI) with the cadmium zinc telluride (CZT) single photon emission computed tomography (SPECT) camera is not well established. Therefore, the aim of the current study was to evaluate the prognostic value of MPI performed with a CZT SPECT camera in a large cohort of patients suspected for coronary artery disease (CAD). Methods: 4057 consecutive symptomatic stable patients without a history of CAD underwent CZT SPECT MPI. During a median follow-up of 2.4 years (25th-75th percentile:1...
April 27, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28426881/new-generation-czt-cameras-the-future-of-infection-imaging
#5
Francois Rouzet, Joël Aerts, Fabien Hyafil, Dominique Le Guludec
No abstract text is available yet for this article.
February 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28330669/czt-spect-reaching-its-potential
#6
EDITORIAL
Lawrence M Phillips
No abstract text is available yet for this article.
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28330657/diagnostic-accuracy-of-myocardial-perfusion-imaging-with-czt-technology-systemic-review-and-meta-analysis-of-comparison-with%C3%A2-invasive-coronary-angiography
#7
Francesco Nudi, Ami E Iskandrian, Orazio Schillaci, Mariangela Peruzzi, Giacomo Frati, Giuseppe Biondi-Zoccai
OBJECTIVES: This study sought to summarize the evidence on stress myocardial perfusion imaging (MPI) using cadmium-zinc-telluride (CZT) technology for the diagnosis of obstructive coronary artery disease (CAD). The CZT cameras are newly introduced, and comparative data with the conventional Anger technology (Anger-MPI) are lacking. BACKGROUND: The diagnostic accuracy of Anger-MPI for detection of angiographically significant CAD is well established; however, less evidence is available on the diagnostic accuracy of CZT-MPI...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28276752/new-solid-state-cadmium-zinc-telluride-technology-for-cardiac-single-photon-emission-computed-tomographic-myocardial-perfusion-imaging
#8
REVIEW
Ali B Alenazy, R Glenn Wells, Terrence D Ruddy
Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well established as diagnostic test for patients with suspected or known coronary artery disease. New camera systems have been developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs and reconstruction software. Areas covered: We review the current state of cardiac SPECT, advances in conventional camera technology and the development and clinical validation of solid-state CZT cameras. Expert commentary: The development of CZT systems is timely and addresses current issues for clinical SPECT imaging...
March 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28275896/first-assessment-of-simultaneous-dual-isotope-123-i-99m-tc-cardiac-spect-on-two-different-czt-cameras-a-phantom-study
#9
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini, Alain Manrique
BACKGROUND: We studied the impact of simultaneous dual-isotope acquisition on (123)I/(99m)Tc mismatch assessment using two CZT cameras (DNM 530c, GE Healthcare and DSPECT, Biosensors International). METHODS: We used an anthropomorphic torso phantom (respectively filled with a solution of (123)I alone, (99m)Tc alone, and a mixture of (123)I and (99m)Tc) and its cardiac insert with two defects mimicking two matched and mismatched defects. Mismatch extent and reconstructed image contrast were evaluated...
March 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28244436/development-of-new-cdznte-detectors-for-room-temperature-high-flux-radiation-measurements
#10
Leonardo Abbene, Gaetano Gerardi, Giuseppe Raso, Fabio Principato, Nicola Zambelli, Giacomo Benassi, Manuele Bettelli, Andrea Zappettini
Recently, CdZnTe (CZT) detectors have been widely proposed and developed for room-temperature X-ray spectroscopy even at high fluxes, and great efforts have been made on both the device and the crystal growth technologies. In this work, the performance of new travelling-heater-method (THM)-grown CZT detectors, recently developed at IMEM-CNR Parma, Italy, is presented. Thick planar detectors (3 mm thick) with gold electroless contacts were realised, with a planar cathode covering the detector surface (4.1 mm × 4...
March 1, 2017: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/28198517/a-monte-carlo-study-for-optimizing-the-detector-of-spect-imaging-using-a-xcat-human-phantom
#11
Mohammad Khoshakhlagh, Jalil Pirayesh Islamian, Seyyed Mohammad Abedi, Babak Mahmoudian, Masoud Shayesteh Azar
BACKGROUND: Acquiring a high quality image has assigned an important concern for obtaining accurate diagnosis in nuclear medicine. Detector is a critical component of Single Photon Emission Computed Tomography (SPECT) imaging system for giving accurate information from exact pattern of radionuclide distribution in the target organ. The images are strongly affected by the attenuation, scattering, and response of the detector. The conventional detector is mainly made from sodium iodide activated by thallium [NaI(Tl)] in nuclear medicine imaging...
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28194726/validation-of-cadmium-zinc-telluride-camera-for-measurement-of-left-ventricular-systolic-performance
#12
Elisabeth Coupez, Charles Merlin, Viateur Tuyisenge, Laurent Sarry, Bruno Pereira, Jean René Lusson, Louis Boyer, Lucie Cassagnes
BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI...
February 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28176253/tl-201-dosing-for-czt-spect-more-new-information
#13
EDITORIAL
M J Henzlova, W L Duvall
No abstract text is available yet for this article.
February 7, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28161604/-135-xe-measurements-with-a-two-element-czt-based-radioxenon-detector-for-nuclear-explosion-monitoring
#14
Lily Ranjbar, Abi T Farsoni, Eric M Becker
Measurement of elevated concentrations of xenon radioisotopes ((131m)Xe, (133m)Xe, (133)Xe and (135)Xe) in the atmosphere has been shown to be a very powerful method for verifying whether or not a detected explosion is nuclear in nature. These isotopes are among the few with enough mobility and with half-lives long enough to make their detection at long distances realistic. Existing radioxenon detection systems used by the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) suffer from problems such as complexity, need for high maintenance and memory effect...
April 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28160264/impact-of-data-driven-cardiac-respiratory-motion-correction-on-the-extent-and-severity-of-myocardial-perfusion-defects-with-free-breathing-czt-spect
#15
Doumit Daou, Rémy Sabbah, Carlos Coaguila, Hatem Boulahdour
BACKGROUND: We previously reported the clinical feasibility and positive impact on image characteristics of a data-driven cardiac respiratory motion (RM) correction method (REGAT) applicable to CZT SPECT myocardial perfusion imaging (MPI). Here, we evaluate its impact on the extent and severity of myocardial perfusion defects (MPD). METHODS: We included 25 patients having a 1-day (99m)Tc-Tetrofosmin stress/rest MPI acquired with multi-pinhole CZT SPECT. Acquisitions were processed with REGAT to generate mean RM gated SPECT...
February 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28133745/technical-note-development-of-a-combined-molecular-breast-imaging-ultrasound-system-for-diagnostic-evaluation-of-mbi-detected-lesions
#16
Michael K O'Connor, Melissa M Morrow, Thuy Tran, Carrie B Hruska, Amy L Conners, Katie N Hunt
PURPOSE: The purpose of this study was to perform a pilot evaluation of an integrated molecular breast imaging/ultrasound (MBI/US) system designed to enable, in real-time, the registration of US to MBI and diagnostic evaluation of breast lesions detected on MBI. METHODS: The MBI/US system was constructed by modifying an existing dual-head cadmium zinc telluride (CZT)-based MBI gamma camera. The upper MBI detector head was replaced with a mesh panel, which allowed an ultrasound probe to access the breast...
February 2017: Medical Physics
https://www.readbyqxmd.com/read/28108979/analysis-of-stress-only-imaging-comparing-upright-and-supine-czt-camera-acquisition-to-conventional-gamma-camera-images-with-and-without-attenuation-correction-with-coronary-angiography-as-a-reference
#17
Zenith A Jameria, Mouhamad Abdallah, Mariano Fernandez-Ulloa, Robert O'Donnell, Alok K Dwivedi, Erica Washburn, Naseer Khan, Mahyar Khaleghi, Nischelle Kalakota, Myron C Gerson
BACKGROUND: Diagnostic performance of stress-only imaging using a Cadmium-Zinc-Telluride (CZT) camera has not been directly compared in the same patients to stress-only attenuation-corrected conventional Anger camera images. METHODS: 112 subjects with correlative coronary angiographic data and 40 subjects with <5% pre-test likelihood of coronary disease completed attenuation-corrected stress-only images on a conventional Anger camera and uncorrected upright and supine stress images on a CZT camera...
January 20, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28097211/new-generation-small-animal-positron-emission-tomography-system-for-molecular-imaging
#18
Shiva Abbaszadeh, Craig S Levin
The next generation of discoveries in molecular imaging requires positron emission tomography (PET) systems with high spatial resolution and high sensitivity to visualize and quantify low concentrations of molecular probes. The goal of this work is to assemble and explore such a system. We use cadmium zinc telluride (CZT) to achieve high spatial resolution, three-dimensional interaction positioning, and excellent energy resolution. The CZT crystals are arranged in an edge-on configuration with a minimum gap of [Formula: see text] in a four-sided panel geometry to achieve superior photon sensitivity...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28048627/tu-fg-209-03-exploring-the-maximum-count-rate-capabilities-of-photon-counting-arrays-based-on-polycrystalline-silicon
#19
A K Liang, M Koniczek, L E Antonuk, Y El-Mohri, Q Zhao
PURPOSE: Photon counting arrays (PCAs) offer several advantages over conventional, fluence-integrating x-ray imagers, such as improved contrast by means of energy windowing. For that reason, we are exploring the feasibility and performance of PCA pixel circuitry based on polycrystalline silicon. This material, unlike the crystalline silicon commonly used in photon counting detectors, lends itself toward the economic manufacture of radiation tolerant, monolithic large area (e.g., ∼43×43 cm2) devices...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047792/su-c-206-01-impact-of-charge-sharing-effect-on-sub-pitch-resolution-for-czt-based-photon-counting-ct-systems
#20
X Zheng, Z Cheng, J Deen, H Peng, L Xing
PURPOSES: Photon counting CT is a new imaging technology that can provide tissue composition information such as calcium/iodine content quantification. Cadmium zinc telluride CZT is considered a good candidate the photon counting CT due to its relatively high atomic number and band gap. One potential challenge is the degradation of both spatial and energy resolution as the fine electrode pitch is deployed (<50 µm). We investigated the extent of charge sharing effect as functions of gap width, bias voltage and depth-of-interaction (DOI)...
June 2016: Medical Physics
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