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https://www.readbyqxmd.com/read/29131809/positioning-true-coincidences-that-undergo-inter-and-intra-crystal-scatter-for-a-sub-mm-resolution-cadmium-zinc-telluride-based-pet-system
#1
Shiva Abbaszadeh, Garry Chinn, Craig S Levin
The kinematics of Compton scatter can be used to estimate the interaction sequence of inter-crystal scatter interactions in 3-D position-sensitive cadmium zinc telluride (CZT) detectors. However, in the case of intra-crystal scatter in a "cross-strip" CZT detector slab, multiple anode and cathode strips may be triggered, creating position ambiguity due to uncertainty in possible combinations of anode-cathode pairings. As a consequence, methods such as energy-weighted centroid are not applicable to position the interactions...
November 13, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29127244/imaging-of-the-thyroid-and-parathyroid-using-a-cardiac-cadmium-zinc-telluride-camera-phantom-studies
#2
Yosuke Miyazaki, Yasuhiro Kato, Akira Imoto, Kazuki Fukuchi
Purpose: Cadmium zinc telluride (CZT) detectors have recently been introduced to the field of clinical nuclear cardiology. However, the feasibility of using them for organs other than the heart remains unclear. The aim of this study was to evaluate the potential of a cardiac CZT camera to acquire thyroid and parathyroid images. We used custom-made phantoms and the currently available standard protocols for CZT, instead of a sodium-iodine scintillation (NaI) camera. Materials and Methods: Thyroid phantoms with or without parathyroid adenomas were made from agar using radiopharmaceuticals ((99m)Tc or (123)I) and imaged using CZT and NaI cameras...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29114176/detecting-triple-vessel-disease-with-cadmium-zinc-telluride-based-single-photon-emission-computed-tomography-using-the-intensity-signal-to-noise-ratio-between-rest-and-stress-studies
#3
Yu-Hua Dean Fang, Tzu-Pei Su, Chi-Jen Chang, Kung-Chu Ho, May Su, Tzu-Chen Yen
The purpose of this study was to investigate if a novel parameter, the stress-to-rest ratio of the signal-to-noise ratio (RSNR) obtained with a cadmium zinc telluride (CZT) SPECT scanner, could be used to distinguish triple-vessel disease (TVD) patients. Methods. One hundred and two patients with suspected coronary artery disease were retrospectively involved. Each subject underwent a Tl-201 SPECT scan and subsequent coronary angiography. Subjects were separated into TVD (n = 41) and control (n = 61) groups based on coronary angiography results using 50% as the stenosis cutoff...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29074271/insical-a-tool-for-calculating-calibration-factors-and-activity-concentrations-in-in-situ-gamma-spectrometry
#4
Alexander Mauring, Tim Vidmar, Torbjörn Gäfvert, Jon Drefvelin, Aldo Fazio
In situ gamma spectrometry is a widely applied analysis technique for the determination of radioactivity levels in soil. Compared to traditional laboratory analysis of soil samples, in situ techniques offer a quick and low-cost way of obtaining accurate results from on-site measurements. However, although the technique is well-known, the dependence of in situ gamma spectrometry on complex and time-consuming calibration procedures as well as in-depth knowledge of the geometric distribution of the source in the ground deters many potential users from employing it in their routine work...
October 23, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29072608/precise-aperture-dependent-motion-compensation-with-frequency-domain-fast-back-projection-algorithm
#5
Man Zhang, Guanyong Wang, Lei Zhang
Precise azimuth-variant motion compensation (MOCO) is an essential and difficult task for high-resolution synthetic aperture radar (SAR) imagery. In conventional post-filtering approaches, residual azimuth-variant motion errors are generally compensated through a set of spatial post-filters, where the coarse-focused image is segmented into overlapped blocks concerning the azimuth-dependent residual errors. However, image domain post-filtering approaches, such as precise topography- and aperture-dependent motion compensation algorithm (PTA), have difficulty of robustness in declining, when strong motion errors are involved in the coarse-focused image...
October 26, 2017: Sensors
https://www.readbyqxmd.com/read/29043554/evaluation-of-left-ventricular-mass-on-cadmium-zinc-telluride-imaging-validation-against-cardiac-magnetic-resonance
#6
Alessia Gimelli, Riccardo Liga, Serena Magro, Salvatore Novo, Roberto Pedrinelli, Anna Sonia Petronio, Paolo Marzullo, Alessia Pepe
BACKGROUND: Single-photon emission computed tomography has shown relevant limitations in the quantification of left ventricular (LV) mass. We sought to compare the estimates of LV mass on Cadmium-Zinc-Telluride (CZT) myocardial perfusion imaging (MPI) as compared to cardiac magnetic resonance (CMR). METHODS AND RESULTS: Twenty-five patients underwent MPI on a CZT camera and CMR on a 1.5 T scanner within 12 ± 3 weeks. LV mass was quantified on CZT images using two softwares: 4D-MSPECT (4DM) and Emory Cardiac Toolbox (ECTb)...
October 17, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28865679/quantification-of-myocardial-perfusion-reserve-using-dynamic-spect-images-of-patients-with-chronic-kidney-disease
#7
Noriko Tsuda, Shinya Shiraishi, Fumi Sakamoto, Hideaki Yuki, Koji Ogasawara, Morikatsu Yoshida, Seiji Tomiguchi, Kenichi Tsujita, Yasuyuki Yamashita
BACKGROUND: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disorders. The aim of this study was to examine whether the quantitatively measured myocardial blood flow (MBF) or myocardial perfusion reserve (MPR), calculated by dynamic single photon emission computed tomography (SPECT) analysis using a cardiac cadmium zinc telluride (CZT) gamma camera, was related to renal dysfunction in patients with normal myocardial perfusion imaging (MPI) findings. METHODS: The study population consisted of 46 patients with CKD and 46 individuals without CKD (controls)...
August 30, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28822102/effect-of-a-patient-specific-minimum-activity-in-stress-myocardial-perfusion-imaging-using-czt-spect-prognostic-value-radiation-dose-and-scan-outcome
#8
J D van Dijk, N M Borren, M Mouden, J A van Dalen, J P Ottervanger, P L Jager
BACKGROUND: SPECT Myocardial perfusion imaging (MPI) is associated with a relatively high radiation burden and decreasing image quality in heavy patients. Patient-specific low-activity protocols (PLAPs) are suggested but follow-up data is lacking. Our aim was to compare the use of a standard fixed-activity protocol (FAP) with a PLAP in cadmium zinc telluride (CZT)-SPECT MPI. METHODS: We retrospectively included 1255 consecutive patients who underwent CZT-SPECT stress-optional rest MPI...
August 18, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28817662/single-scan-rest-stress-imaging-with-99mtc-sestamibi-and-cadmium-zinc-telluride-based-spect-for-hyperemic-flow-quantification-a-feasibility-study-evaluated-with-cardiac-magnetic-resonance-imaging
#9
Yu-Hua Dean Fang, Yuan-Chang Liu, Kung-Chu Ho, Feng-Cheng Kuo, Ching-Fang Yang, Tzu-Chen Yen, I-Chang Hsieh
INTRODUCTION: We aimed to evaluate whether the hyperemic myocardial blood flow (MBF) can be estimated using cadmium zinc telluride (CZT)-based single-photon emission computed tomography (SPECT) cameras with a single, rapid rest/stress dynamic scan. Dynamic contrast-enhanced (DCE) cardiac magnetic resonance imaging (MRI) was used as a reference modality for flow measurement. MATERIALS AND METHODS: The proposed protocol included both the rest and stress acquisitions within a 24-min scan...
2017: PloS One
https://www.readbyqxmd.com/read/28808889/interactions-between-myocardial-sympathetic-denervation-and-left-ventricular-mechanical-dyssynchrony-a-czt-analysis
#10
Alessia Gimelli, Riccardo Liga, Francesca Menichetti, Ezio Soldati, Maria Grazia Bongiorni, Paolo Marzullo
BACKGROUND: A correlation between left ventricular (LV) dyssynchrony (LVD) and impaired myocardial sympathetic tone has been hypothesized. We sought to assess the interactions between regional LV sympathetic innervation, perfusion, and mechanical dyssynchrony. METHODS: Eighty-three patients underwent evaluation of LV perfusion and sympathetic innervation on (99m)Tc-tetrofosmin/(123)I-metaiodobenzylguanidine ((123)I-MIBG) imaging. The summed rest score and summed (123)I-MIBG score (SS-MIBG) were computed...
August 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28776313/a-new-era-in-gated-myocardial-perfusion-imaging-feasibility-of-data-driven-cardiac-contraction-gating-with-multiple-pinhole-czt-spect
#11
Doumit Daou, Rémy Sabbah, Carlos Coaguila, Yousef Alattar, Hatem Boulahdour
BACKGROUND: We previously validated the use of a data-driven cardiac respiratory-motion (RM) correction method (REGAT) applicable to CZT SPECT myocardial perfusion imaging (MPI). In this study, we adapted the same process used with REGAT for RM to generate data-driven cardiac contraction triggers and corresponding cardiac contraction-gated SPECT studies (GSPECT-DD). We aimed to study its feasibility and compare its performances to GSPECT studies generated with ECG monitor-based triggers (GSPECT-ECG)...
August 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28744820/dedicated-cardiac-czt-spect-is-steadily-moving-to-achieve-its-destiny
#12
EDITORIAL
Doumit Daou
No abstract text is available yet for this article.
July 25, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28695497/comparison-of-ctac-and-prone-imaging-for-the-detection-of-coronary-artery-disease-using-czt-spect
#13
Shimpei Ito, Akihiro Endo, Taiji Okada, Taku Nakamura, Takashi Sugamori, Nobuyuki Takahashi, Hiroyuki Yoshitomi, Kazuaki Tanabe
BACKGROUND: Cadmium-zinc-telluride (CZT) cameras have improved the evaluation of patients with chest pain. However, inferior/inferolateral attenuation artifacts similar to those seen with conventional Anger cameras persist. We added prone acquisitions and CT attenuation correction (CTAC) to the standard supine image acquisition and analyzed the resulting examinations. METHODS AND RESULTS: Seventy-two patients referred for invasive coronary angiography (CAG), and who also underwent rest/stress myocardial perfusion imaging (MPI) on a CZT camera in the supine and prone positions plus CTAC imaging, to examine known or suspected CAD between April 2013 and March 2014 were included...
July 10, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28675445/europium-155-as-a-source-for-dual-energy-cone-beam-computed-tomography-in-adaptive-proton-therapy-a-simulation-study
#14
Jiahua Zhu, Scott N Penfold
PURPOSE: To investigate the feasibility of a 3D imaging system utilizing a (155) Eu source and pixelated cadmium-zinc-telluride (CZT) detector for applications in adaptive radiotherapy. Specifically, to compare the reconstructed stopping power ratio (SPR) values of a head phantom obtained with the proposed imaging technique with theoretical SPR values. METHOD: A Geant4 Monte Carlo simulation was performed with the novel imaging system. The simulation was repeated with a typical 120 kV X-ray tube spectrum while maintaining all other parameters...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/28664482/prognostic-value-of-a-faster-low-radiation-myocardial-perfusion-spect-protocol-in-a-czt-camera
#15
Ronaldo S L Lima, Thaís R Peclat, Ana Carolina A H Souza, Aline M K Nakamoto, Felipe M Neves, Victor F Souza, Letícia B Glerian, Andrea De Lorenzo
To determine the prognostic value of a new, ultrafast, low dose myocardial perfusion SPECT (MPS) protocol in a cadmium-zinc telluride (CZT) camera. CZT cameras have introduced significant progress in MPS imaging, offering high-quality images despite lower doses and scan time. Yet, it is unknown if, with such protocol changes, the prognostic value of MPS is preserved. Patients had a 1-day 99 m-Tc-sestamibi protocol, starting with the rest (185-222 MBq) followed by stress (666-740 MBq). Acquisition times were 6 and 3 min, respectively...
June 29, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28664481/comparison-of-conventional-and-cadmium-zinc-telluride-single-photon-emission-computed-tomography-for-analysis-of-thallium-201-myocardial-perfusion-imaging-an-exploratory-study-in-normal-databases-for-different-ethnicities
#16
Masaru Ishihara, Masahisa Onoguchi, Yasuyo Taniguchi, Takayuki Shibutani
The aim of this study was to clarify the differences in thallium-201-chloride (thallium-201) myocardial perfusion imaging (MPI) scans evaluated by conventional anger-type single-photon emission computed tomography (conventional SPECT) versus cadmium-zinc-telluride SPECT (CZT SPECT) imaging in normal databases for different ethnic groups. MPI scans from 81 consecutive Japanese patients were examined using conventional SPECT and CZT SPECT and analyzed with the pre-installed quantitative perfusion SPECT (QPS) software...
June 29, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28646293/diagnostic-implications-of-czt-spect-and-impact-of-ct-attenuation-correction
#17
EDITORIAL
Andrew Peters, Jeevan Kumar, Pravin V Patil
No abstract text is available yet for this article.
June 23, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28646015/determination-of-the-heart-to-mediastinum-ratio-of-123-i-mibg-uptake-using-dual-isotope-123-i-mibg-99m-tc-tetrofosmin-multi-pinhole-czt-spect-in-patients-with-heart-failure
#18
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallègue, Dimitri Bellevre, Denis Agostini, Alain Manrique
The aim of this retrospective study was to determine the heart-to-mediastinum ratio (HMR) of (123)I-metaiodobenzylguanidine (MIBG) uptake obtained using a multi-pinhole cadmium-zinc-telluride (CZT)-based camera (Discovery NM 530c, DNM-530c, GE Healthcare, Milwaukee, WI, USA) in comparison with that obtained using conventional planar imaging (Infinia, GE Healthcare, Milwaukee, WI, USA). Methods: Forty consecutive heart failure patients underwent planar acquisition 4 h after (123)I-MIBG injection (191±41 MBq)...
June 23, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28623525/comparison-of-czt-spect-and-conventional-spect-for-assessment-of-contractile-function-mechanical-synchrony-and-myocardial-scar-in-patients-with-heart-failure
#19
Dayong Wu, Zongyao Zhang, Rongzheng Ma, Feng Guo, Lei Wang, Wei Fang
AIM: The aim of this study was to compare CZT-SPECT (CZT SPECT) to conventional SPECT (C-SPECT) in the assessment of left ventricular myocardial scar, contractile function, and mechanical synchrony in patients with heart failure (HF). METHODS: Fifty-nine patients with HF who were referred for myocardial perfusion/metabolism imaging were enrolled. All patients underwent resting (99m)Tc-MIBI gated myocardial perfusion imaging using a CZT SPECT camera and a C-SPECT camera, respectively, and (18)F-FDG PET myocardial metabolism imaging within three days...
June 16, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28622946/estimation-of-myocardial-flow-reserve-utilizing-an-ultrafast-cardiac-spect-comparison-with-coronary-angiography-fractional-flow-reserve-and-the-syntax-score
#20
Masao Miyagawa, Yoshiko Nishiyama, Teruyoshi Uetani, Akiyoshi Ogimoto, Shuntaro Ikeda, Hayato Ishimura, Emiri Watanabe, Rami Tashiro, Yuki Tanabe, Teruhito Kido, Akira Kurata, Teruhito Mochizuki
BACKGROUND: Quantitative assessment of myocardial flow reserve (MFR) by single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is challenging but may facilitate evaluation of multi-vessel coronary artery disease (CAD). METHODS: We enrolled 153 patients with suspected or known CAD, referred for pharmacological stress MPI. They underwent a (99m)Tc-perfusion stress/rest SPECT with an ultrafast cadmium-zinc-telluride (CZT) camera. Dynamic data were acquired and time-activity curves fitted to a 1-tissue compartment analysis with input function...
June 13, 2017: International Journal of Cardiology
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