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https://www.readbyqxmd.com/read/28108979/analysis-of-stress-only-imaging-comparing-upright-and-supine-czt-camera-acquisition-to-conventional-gamma-camera-images-with-and-without-attenuation-correction-with-coronary-angiography-as-a-reference
#1
Zenith A Jameria, Mouhamad Abdallah, Mariano Fernandez-Ulloa, Robert O'Donnell, Alok K Dwivedi, Erica Washburn, Naseer Khan, Mahyar Khaleghi, Nischelle Kalakota, Myron C Gerson
BACKGROUND: Diagnostic performance of stress-only imaging using a Cadmium-Zinc-Telluride (CZT) camera has not been directly compared in the same patients to stress-only attenuation-corrected conventional Anger camera images. METHODS: 112 subjects with correlative coronary angiographic data and 40 subjects with <5% pre-test likelihood of coronary disease completed attenuation-corrected stress-only images on a conventional Anger camera and uncorrected upright and supine stress images on a CZT camera...
January 20, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28097211/new-generation-small-animal-positron-emission-tomography-system-for-molecular-imaging
#2
Shiva Abbaszadeh, Craig S Levin
The next generation of discoveries in molecular imaging requires positron emission tomography (PET) systems with high spatial resolution and high sensitivity to visualize and quantify low concentrations of molecular probes. The goal of this work is to assemble and explore such a system. We use cadmium zinc telluride (CZT) to achieve high spatial resolution, three-dimensional interaction positioning, and excellent energy resolution. The CZT crystals are arranged in an edge-on configuration with a minimum gap of [Formula: see text] in a four-sided panel geometry to achieve superior photon sensitivity...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28048627/tu-fg-209-03-exploring-the-maximum-count-rate-capabilities-of-photon-counting-arrays-based-on-polycrystalline-silicon
#3
A K Liang, M Koniczek, L E Antonuk, Y El-Mohri, Q Zhao
PURPOSE: Photon counting arrays (PCAs) offer several advantages over conventional, fluence-integrating x-ray imagers, such as improved contrast by means of energy windowing. For that reason, we are exploring the feasibility and performance of PCA pixel circuitry based on polycrystalline silicon. This material, unlike the crystalline silicon commonly used in photon counting detectors, lends itself toward the economic manufacture of radiation tolerant, monolithic large area (e.g., ∼43×43 cm2) devices...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047792/su-c-206-01-impact-of-charge-sharing-effect-on-sub-pitch-resolution-for-czt-based-photon-counting-ct-systems
#4
X Zheng, Z Cheng, J Deen, H Peng, L Xing
PURPOSES: Photon counting CT is a new imaging technology that can provide tissue composition information such as calcium/iodine content quantification. Cadmium zinc telluride CZT is considered a good candidate the photon counting CT due to its relatively high atomic number and band gap. One potential challenge is the degradation of both spatial and energy resolution as the fine electrode pitch is deployed (<50 µm). We investigated the extent of charge sharing effect as functions of gap width, bias voltage and depth-of-interaction (DOI)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046698/mo-fg-campus-iep1-02-dose-reduction-in-contrast-enhanced-digital-mammography-using-a-photon-counting-detector
#5
S Lee, S Kang, J Eom
PURPOSE: Photon-counting detectors (PCDs) allow multi-energy X-ray imaging without additional exposures and spectral overlap. This capability results in the improvement of accuracy of material decomposition for dual-energy X-ray imaging and the reduction of radiation dose. In this study, the PCD-based contrast-enhanced dual-energy mammography (CEDM) was compared with the conventional CDEM in terms of radiation dose, image quality and accuracy of material decomposition. METHODS: A dual-energy model was designed by using Beer-Lambert's law and rational inverse fitting function for decomposing materials from a polychromatic X-ray source...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028761/relationships-between-left-ventricular-sympathetic-innervation-and-diastolic-dysfunction-the-role-of-myocardial-innervation-perfusion-mismatch
#6
Alessia Gimelli, Riccardo Liga, Francesco Avogliero, Michele Coceani, Paolo Marzullo
BACKGROUND: A possible relationship between cardiac sympathetic denervation and left ventricular (LV) diastolic dysfunction has been suggested. However, an evaluation of the interactions between myocardial adrenergic tone and LV perfusion and diastolic function is lacking. METHODS AND RESULTS: Seventy-two patients underwent (99m)Tc-tetrofosmin/(123)I-metaiodobenzylguanidine ((123)I-MIBG) cardiac Cadmium-Zinc-Telluride (CZT) imaging. The summed rest score (SRS) and summed (123)I-MIBG score (SS-MIBG) were computed as measures of regional perfusion and innervation heterogeneities...
December 27, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28008559/optimal-thallium-201-dose-in-cadmium-zinc-telluride-spect-myocardial-perfusion-imaging
#7
Masaru Ishihara, Yasuyo Taniguchi, Masahisa Onoguchi, Takayuki Shibutani
BACKGROUND: We aimed to determine the optimal thallium 201 chloride (thallium-201) dose using a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors (D-SPECT). METHODS AND RESULTS: The optimal thallium-201 dose for obtaining left ventricular (LV) myocardial counts was determined from a phantom study. Consecutive 292 patients underwent stress myocardial perfusion imaging with a thallium-201 injection. Stress test comprised exercise or pharmacological (adenosine) provocation...
December 22, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27845567/spect-ct-an-update-on-technological-developments-and-clinical-applications
#8
Michael Ljungberg, P Hendrik Pretorius
Functional nuclear medicine imaging with Single-Photon Emission Computed Tomography (SPECT) in combination with anatomical Computed Tomography (CT) has been commercially available since the beginning of this century. The combination of the two modalities has improved both sensitivity and specificity of many clinical applications and CT in conjunction with SPECT allows for spatial overlay of the SPECT data on good anatomy images. Introduction of diagnostic CT units as part of the SPECT/CT system has also potentially allowed for a more cost-efficient use of the equipment...
November 15, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27837548/left-ventricular-function-assessment-using-123-i-99m-tc-dual-isotope-acquisition-with-two-semi-conductor-cadmium-zinc-telluride-czt-cameras-a-gated-cardiac-phantom-study
#9
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini, Alain Manrique
BACKGROUND: The impact of increased energy resolution of cadmium-zinc-telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions ((99m)Tc and (123)I) remains unknown. The Amsterdam-gated dynamic cardiac phantom (AGATE, Vanderwilt techniques, Boxtel, The Netherlands) was successively filled with a solution of (123)I alone, (99m)Tc alone, and a mixture of (123)I and (99m)Tc. A total of 12 datasets was acquired with each commercially available CZT camera (DNM 530c, GE Healthcare and DSPECT, Biosensors International) using both energy windows ((99m)Tc or (123)I) with ejection fraction set to 33, 45, and 60 %...
December 2016: EJNMMI Physics
https://www.readbyqxmd.com/read/27795606/evaluation-of-a-photon-counting-medipix3rx-czt-spectral-x-ray-detector
#10
Steven M Jorgensen, Andrew J Vercnocke, David S Rundle, Philip H Butler, Cynthia H McCollough, Erik L Ritman
We assessed the performance of a cadmium zinc telluride (CZT)-based Medipix3RX x-ray detector as a candidate for micro-computed tomography (micro-CT) imaging. This technology was developed at CERN for the Large Hadron Collider. It features an array of 128 by 128, 110 micrometer square pixels, each with eight simultaneous threshold counters, five of which utilize real-time charge summing, significantly reducing the charge sharing between contiguous pixels. Pixel response curves were created by imaging a range of x-ray intensities by varying x-ray tube current and by varying the exposure time with fixed x-ray current...
August 28, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/27677613/routine-evaluation-of-left-ventricular-function-using-czt-spect-with-low-injected-activities-and-limited-recording-times
#11
Marine Claudin, Laetitia Imbert, Wassila Djaballah, Nicolas Veran, Sylvain Poussier, Véronique Roch, Mathieu Perrin, Antoine Verger, Henri Boutley, Gilles Karcher, Pierre-Yves Marie
PURPOSE: Gamma-cameras, with Cadmium-Zinc-Telluride (CZT) detectors, allow to perform myocardial perfusion imaging (MPI) with limited injected activities and recorded times. This study aimed at determining whether the routine assessment of left ventricular (LV) function with such limited counts protocols compares well with reference values from cardiac MRI. METHODS: The study included patients who have undergone cardiac MRI and an MPI routinely planned on a CZT camera with a low-dose protocol (120 MBq of Sestamibi for stress and 360 MBq at rest for 75 kg body weight), while targeting the recording of only 500 myocardial kcounts in order to limit the recording times (<10 minutes for stress, <4 minutes for rest)...
September 27, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27614638/perovskite-type-titanate-zirconate-as-photocatalyst-for-textile-wastewater-treatment
#12
A M Ferrari-Lima, A C Ueda, E A Bergamo, R G Marques, E A V Ferri, C S Pinto, C A A Pereira, P H Yassue-Cordeiro, R P Souza
Calcium titanate zirconate, Ca(Ti(1-x)Zrx)O3 (CZT), powders have been synthesised by the polymeric precursor method. The structural analysis of the CZT powders was monitored by X-ray diffraction (XRD), photoacoustic spectroscopy (PAS) and textural analysis. The photocatalytic properties were evaluated by methylene blue (MB) decomposition and real textile wastewater (RTW) combined treatment (coagulation/flocculation/photocatalysis). Chemical oxygen demand (COD) of RTW was successfully reduced from 6195 mg L(-1) (untreated) to 662 mg L(-1) after coagulation/flocculation with a tannin-based coagulant (Tanfloc®) and finally to 471 mg L(-1) after combined treatment (coagulation/flocculation/photocatalysis) applying ultraviolet radiation and CaTiO3 as photocatalyst...
September 10, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27551981/characterization-of-a-sub-assembly-of-3d-position-sensitive-cadmium-zinc-telluride-detectors-and-electronics-from-a-sub-millimeter-resolution-pet-system
#13
Shiva Abbaszadeh, Yi Gu, Paul D Reynolds, Craig S Levin
Cadmium zinc telluride (CZT) offers key advantages for small animal positron emission tomography (PET), including high spatial and energy resolution and simple metal deposition for fabrication of very small pixel arrays. Previous studies have investigated the intrinsic spatial, energy, and timing resolution of an individual sub-millimeter resolution CZT detector. In this work we present the first characterization results of a system of these detectors. The 3D position sensitive dual-CZT detector module and readout electronics developed in our lab was scaled up to complete a significant portion of the final PET system...
September 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27542010/performance-of-cardiac-cadmium-zinc-telluride-gamma-camera-imaging-in-coronary-artery-disease-a-review-from-the-cardiovascular-committee-of-the-european-association-of-nuclear-medicine-eanm
#14
REVIEW
Denis Agostini, Pierre-Yves Marie, Simona Ben-Haim, François Rouzet, Bernard Songy, Alessandro Giordano, Alessia Gimelli, Fabien Hyafil, Roberto Sciagrà, Jan Bucerius, Hein J Verberne, Riemer H J A Slart, Oliver Lindner
The trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may overcome some of the limitations against conventional gamma cameras. CZT cameras used for the evaluation of myocardial perfusion have been shown to have a higher count sensitivity compared to conventional single photon emission computed tomography (SPECT) techniques...
December 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27538570/applicability-of-data-driven-respiratory-motion-correction-to-czt-spect-myocardial-perfusion-imaging-in-the-clinical-setting-the-birth-of-an-old-wish
#15
Doumit Daou, Remy Sabbah, Carlos Coaguila, Hatem Boulahdour
No abstract text is available yet for this article.
August 18, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27510176/comparison-of-the-prognostic-value-of-myocardial-perfusion-imaging-using-a-czt-spect-camera-with-a-conventional-anger-camera
#16
Ronaldo Lima, Thais Peclat, Thalita Soares, Caio Ferreira, Ana Carolina Souza, Gabriel Camargo
BACKGROUND: Recent studies have shown that myocardial perfusion imaging (MPI) in cadmium-zinc-telluride (CZT) cameras allow faster exams with less radiation dose but there are little data comparing its prognosis information with that of dedicated cardiac Na-I SPECT cameras OBJECTIVE: The objective of this study is to compare the prognostic value of MPI using an ultrafast protocol with low radiation dose in a CZT-SPECT and a traditional one. METHODS: Group 1 was submitted to a two-day MIBI protocol in a conventional camera, and group 2 was submitted to a 1-day MIBI protocol in CZT camera...
August 10, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27506702/prognostic-value-of-one-millisievert-exercise-myocardial-perfusion-imaging-in-patients-without-known-coronary-artery-disease
#17
Bernard Songy, Mohamed Guernou, Daniel Hivoux, David Attias, David Lussato, Mathieu Queneau, Gerald Bonardel, Marc Bertaux
: The aim of this study was to assess the prognostic value of normal ultra-low-dose exercise MPI with a CZT camera. METHODS: 1901 consecutive patients without known CAD referred for exercise MPI with 1.8 MBq/kg (0.05 mCi) of Tc99m sestamibi or tetrofosmin and a CZT camera were included prospectively. Patients with an abnormal scan requiring an additional resting image (230) or a submaximal exercise test (271) were excluded. The 1400 remaining patients were followed for 39 months...
August 9, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27487904/resolution-recovery-for-compton-camera-using-origin-ensemble-algorithm
#18
A Andreyev, A Celler, I Ozsahin, A Sitek
PURPOSE: Compton cameras (CCs) use electronic collimation to reconstruct the images of activity distribution. Although this approach can greatly improve imaging efficiency, due to complex geometry of the CC principle, image reconstruction with the standard iterative algorithms, such as ordered subset expectation maximization (OSEM), can be very time-consuming, even more so if resolution recovery (RR) is implemented. We have previously shown that the origin ensemble (OE) algorithm can be used for the reconstruction of the CC data...
August 2016: Medical Physics
https://www.readbyqxmd.com/read/27469371/simultaneous-dual-isotope-solid-state-detector-spect-for-improved-tracking-of-white-blood-cells-in-suspected-endocarditis
#19
Federico Caobelli, Tim Wollenweber, Udo Bavendiek, Christian Kühn, Christian Schütze, Lilli Geworski, James T Thackeray, Johann Bauersachs, Axel Haverich, Frank M Bengel
AIMS: High-energy resolution and sensitivity of novel cadmium-zinc-telluride (CZT) detector equipped SPECT systems facilitate simultaneous imaging of multiple isotopes and may enhance the detection of molecular/cellular signals. This may refine the detection of endocarditis. This study was designed to determine the feasibility and diagnostic accuracy of simultaneous imaging of inflammation with (111)In-labeled white blood cells (WBCs) and myocardial perfusion with (99m)Tc-sestamibi, for localization of WBCs relative to the valve plane in suspected endocarditis...
July 28, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27430947/relationships-between-cardiac-innervation-perfusion-imbalance-and-ventricular-arrhythmias-impact-on-invasive-electrophysiological-parameters-and-ablation-procedures
#20
Alessia Gimelli, Francesca Menichetti, Ezio Soldati, Riccardo Liga, Andrea Vannozzi, Paolo Marzullo, Maria Grazia Bongiorni
PURPOSE: To assess the relationship between regional myocardial perfusion and sympathetic innervation parameters at myocardial scintigraphy and intra-cavitary electrophysiological data in patients with ventricular arrhythmias (VA) submitted to invasive electrophysiological study and ablation procedure. METHODS: Sixteen subjects underwent invasive electrophysiological study with electroanatomical mapping (EAM) followed by trans-catheter ablations of VA. Before ablation all patients were studied with a combined evaluation of regional myocardial perfusion and sympathetic innervation by means of tomographic (99m)Tc-tetrofosmin and (123)I- metaiodobenzylguanidine cadmium-zinc-telluride (CZT) scintigraphies, respectively...
July 19, 2016: European Journal of Nuclear Medicine and Molecular Imaging
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