keyword
https://read.qxmd.com/read/38163304/exploration-of-coincidence-detection-of-cascade-photons-to-enhance-preclinical-multi-radionuclide-spect-imaging
#21
JOURNAL ARTICLE
Yifei Jin, Ling-Jian Meng
We proposed a technique of coincidence detection of cascade photons (CDCP) to enhance preclinical SPECT imaging of therapeutic radionuclides emitting cascade photons, such as Lu-177, Ac-225, Ra-223, and In-111. We have carried out experimental studies to evaluate the proposed CDCP-SPECT imaging of low-activity radionuclides using a prototype coincidence detection system constructed with large-volume cadmium zinc telluride (CZT) imaging spectrometers and a pinhole collimator. With In-111 in experimental studies, the CDCP technique allows us to improve the signal-to-contamination in the projection (Projection-SCR) by ~53 times and reduce ~98% of the normalized contamination...
January 1, 2024: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/38114618/effects-of-medication-on-dopamine-transporter-imaging-using-123-i-i-fp-cit-spect-in-routine-practice
#22
JOURNAL ARTICLE
Yuliya Piatkova, Matthieu Doyen, Sébastien Heyer, Ayaz Tahmazov, Solene Frismand, Lucie Hopes, Laetitia Imbert, Antoine Verger
PURPOSE: Dopamine transporter (DAT) imaging is used to support the diagnosis of neurodegenerative parkinsonian disorders. Specific medications have been reported to confound the interpretation of [123 I]I-FP-CIT SPECT scans, but there is limited data. The aim of the current study is to identify potential medication effects on the interpretation of [123 I]I-FP-CIT SPECT scans in routine practice. MATERIALS AND METHODS: Consecutive patients undergoing a [123 I]I-FP-CIT SPECT/CT scan on a 360° CZT camera between September 2019 and December 2022 were included...
December 20, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38082197/ultra-fast-whole-body-bone-tomoscintigraphies-achieved-with-a-high-sensitivity-360%C3%A2-czt-camera-and-a-dedicated-deep-learning-noise-reduction-algorithm
#23
JOURNAL ARTICLE
Achraf Bahloul, Antoine Verger, Yechiel Lamash, Nathaniel Roth, Diawad Dari, Pierre-Yves Marie, Laetitia Imbert
UNLABELLED: This study aimed to determine whether the whole-body bone Single Photon Emission Computed Tomography (SPECT) recording times of around 10 min, routinely provided by a high-sensitivity 360° cadmium and zinc telluride (CZT) camera, can be further reduced by a deep-learning noise reduction (DLNR) algorithm. METHODS: DLNR was applied on whole-body images recorded after the injection of 545 ± 33 MBq of [99m Tc]Tc-HDP in 19 patients (14 with bone metastasis) and reconstructed with 100%, 90%, 80%, 70%, 60%, 50%, 40%, and 30% of the original SPECT recording times...
December 12, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37930612/correction-to-the-incremental-value-of-coronary-artery-calcium-score-in-predicting-long-term-prognosis-and-defining-the-warranty-period-of-normal-adenosine-stress-only-myocardial-perfusion-imaging-using-czt-spect
#24
Mandy Kamerman, Joris D van Dijk, Jorik R Timmer, Jan Paul Ottervanger, Siert Knollema, Pieter L Jager, Mohamed Mouden
No abstract text is available yet for this article.
November 6, 2023: Journal of Nuclear Cardiology
https://read.qxmd.com/read/37924340/ct-attenuation-correction-improves-quantitative-risk-prediction-by-cardiac-spect-in-obese-patients
#25
JOURNAL ARTICLE
Attila Feher, Konrad Pieszko, Aakash Shanbhag, Mark Lemley, Bryan Bednarski, Robert J H Miller, Cathleen Huang, Leonidas Miras, Yi-Hwa Liu, Albert J Sinusas, Piotr J Slomka, Edward J Miller
PURPOSE: This study aimed to compare the predictive value of CT attenuation-corrected stress total perfusion deficit (AC-sTPD) and non-corrected stress TPD (NC-sTPD) for major adverse cardiac events (MACE) in obese patients undergoing cadmium zinc telluride (CZT) SPECT myocardial perfusion imaging (MPI). METHODS: The study included 4,585 patients who underwent CZT SPECT/CT MPI for clinical indications (chest pain: 56%, shortness of breath: 13%, other: 32%) at Yale New Haven Hospital (age: 64 ± 12 years, 45% female, body mass index [BMI]: 30...
November 4, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37870526/innovations-in-imaging-modalities-a-comparative-review-of-mri-long-axial-field-of-view-pet-and-full-ring-czt-spect-in-detecting-bone-metastases
#26
JOURNAL ARTICLE
Roberto Moretti, Guenda Meffe, Salvatore Annunziata, Amedeo Capotosti
The accurate diagnosis of bone metastasis, a condition in which cancer cells have spread to the bone, is essential for optimal patient care and outcome. This review provides a detailed overview of the current medical imaging techniques used to detect and diagnose this critical condition focusing on three cardinal imaging modalities: positron emission tomography (PET), single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). Each of these techniques has unique advantages: PET/CT combines functional imaging with anatomical imaging, allowing precise localization of metabolic abnormalities; the SPECT/CT offers a wider range of radiopharmaceuticals for visualizing specific receptors and metabolic pathways; MRI stands out for its unparalleled ability to produce high-resolution images of bone marrow structures...
October 23, 2023: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37853247/quantitative-177-lu-spect-ct-imaging-for-personalized-dosimetry-using-a-ring-shaped-czt-based-camera
#27
JOURNAL ARTICLE
Rachele Danieli, Martina Stella, Julian Leube, Johannes Tran-Gia, Clementine Marin, Carlos F Uribe, Bruno Vanderlinden, Nick Reynaert, Patrick Flamen, Hugo Levillain
BACKGROUND: Dosimetry after radiopharmaceutical therapy with 177 Lu (177 Lu-RPT) relies on quantitative SPECT/CT imaging, for which suitable reconstruction protocols are required. In this study, we characterized for the first time the quantitative performance of a ring-shaped CZT-based camera using two different reconstruction algorithms: an ordered subset expectation maximization (OSEM) and a block sequential regularized expectation maximization (BSREM) combined with noise reduction regularization...
October 18, 2023: EJNMMI Physics
https://read.qxmd.com/read/37830324/-myocardial-perfusion-imaging-and-coronary-artery-disease-recent-technological-innovations
#28
Thomas Lejeune, Céline Derwael, Claire Bernard, Gaetan Letesson, Frédéric Daenen, Roland Hustinx
Cardiovascular diseases represent the first cause of mortality in the world. Various exploration methods exist to prevent and diagnose them. Among them, cardiac scintigraphy holds a predominant place. There are various equipments and procedures for its realization. We compared the practical aspects of using a conventional Anger camera (Symbia, Siemens) according to a two-days examination protocol with a dedicated cardio CzT camera (D-Spect, Spectrum Dynamics) according to a two-days protocol and a 360°SPECT/CT CzT camera (Veriton, Spectrum Dynamics) according to a one-day protocol...
October 2023: Revue Médicale de Liège
https://read.qxmd.com/read/37763283/head-to-head-comparison-of-czt-spect-and-spect-ct-myocardial-perfusion-imaging-interobserver-and-intraobserver-agreement-and-diagnostic-performance
#29
JOURNAL ARTICLE
Forough Kalantari, Nasibeh Mohseninia, Andreas Wetsch, Sara Harsini, Lukas Hehenwarter, Gregor Schweighofer-Zwink, Nazanin Zamani-Siahkali, Gundula Rendl, Mohsen Beheshti, Christian Pirich
BACKGROUND: Myocardial perfusion imaging (MPI) plays a crucial role in diagnosing coronary artery disease (CAD), with single-photon emission computed tomography (SPECT) being a widely accepted method. The accuracy of MPI relies on image quality and the expertise of physicians. While CZT-SPECT cameras offer advantages, they can be susceptible to attenuation artifacts. Therefore, our objective was to evaluate the diagnostic accuracy of CZT-SPECT and SPECT/CT in a clinical setting. METHOD: We conducted a prospective single-center study involving patients with known or suspected stable ischemic heart disease who underwent SPECT-MPI using CZT-SPECT and SPECT/CT scanners, and the latter was equipped with cardiofocal collimation...
September 7, 2023: Life
https://read.qxmd.com/read/37756437/dynamic-czt-spect-characterizing-the-lower-values-of-myocardial-blood-flow-and-reserve
#30
JOURNAL ARTICLE
Matthieu Bailly, Maxime Courtehoux, Gilles Metrard, Denis Angoulvant, Maria Joao Ribeiro
CZT-SPECT myocardial perfusion enables quantification of myocardial blood flow (MBF). Normal values and thresholds have been accurately defined in PET but remain unclear in SPECT. The aim of this study was to report normal MBF and myocardial flow reserve values in very low-risk patients referred for coronary artery disease screening with dynamic SPECT, in comparison with patients experiencing coronary artery disease. Eighty-four patients (31 male) were analyzed. The mean 10 years risk of fatal cardiovascular events score was 2...
November 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/37748688/diagnostic-performance-of-a-novel-deep-learning-attenuation-correction-software-for-mpi-using-a-cardio-dedicated-czt-camera-experience-in-the-clinical-practice
#31
JOURNAL ARTICLE
Miguel Ochoa-Figueroa, Carlos Valera-Soria, Christos Pagonis, Marcus Ressner, Pernilla Norberg, Veronica Sanchez-Rodriguez, Jeronimo Frias-Rose, Elin Good, Anette Davidsson
PURPOSE: To evaluate the diagnostic performance of a novel deep learning attenuation correction software (DLACS) for myocardial perfusion imaging (MPI) using a cadmium-zinc-telluride (CZT) cardio dedicated camera with invasive coronary angiography (ICA) correlation for the diagnosis of coronary artery disease (CAD) in a high-risk population. METHODS: Retrospective study of 300 patients (196 males [65%], mean age 68 years) from September 2014 to October 2019 undergoing MPI, followed by ICA and evaluated by means of quantitative angiography software, within six months after the MPI...
September 23, 2023: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/37736779/performance-study-of-a-360%C3%A2-czt-camera-for-monitoring-177-lu-psma-treatment
#32
JOURNAL ARTICLE
Laure Vergnaud, Jean-Noël Badel, Anne-Laure Giraudet, David Kryza, Thomas Mognetti, Thomas Baudier, Hanan Rida, Arnaud Dieudonné, David Sarrut
BACKGROUND: The aim of this study was to investigate the quantification performance of a 360° CZT camera for 177 Lu-based treatment monitoring. METHODS: Three phantoms with known 177 Lu activity concentrations were acquired: (1) a uniform cylindrical phantom for calibration, (2) a NEMA IEC body phantom for analysis of different-sized spheres to optimise quantification parameters and (3) a phantom containing two large vials simulating organs at risk for tests...
September 22, 2023: EJNMMI Physics
https://read.qxmd.com/read/37653261/time-efficient-cardiac-imaging-early-post-injection-stress-first-protocol-myocardial-perfusion-spect-with-a-czt-camera
#33
EDITORIAL
Luca Camoni, Francesco Dondi
No abstract text is available yet for this article.
August 31, 2023: Journal of Nuclear Cardiology
https://read.qxmd.com/read/37646239/technical-concepts-on-blood-pool-phase-spect-acquisition-reconstruction
#34
JOURNAL ARTICLE
Sarah C Cade, Richard N Graham
Guidelines for bone scintigraphy are well established and recommend the use of planar early phase images to investigate a number of clinical indications. With recent advances in gamma camera technology the use of SPECT/CT imaging in the early phases is now possible, offering the potential of improved diagnostic confidence and prognostic value. To date little work has been carried out to optimize the acquisition of early phase bone images using SPECT/CT with most of the available studies acquiring SPECT images after the traditional planar images to allow comparison of the two techniques...
September 2023: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37623913/the-new-bone-wb-spect-ct-hybrid-from-head-to-toe-and-digital-is-it-worth-the-effort
#35
JOURNAL ARTICLE
Luca Filippi, Viviana Frantellizzi, Giuseppe De Vincentis, Orazio Schillaci
INTRODUCTION: A bone scan (BS) plays a pivotal role in many oncological and non-oncological conditions. Planar BS is characterized by high sensitivity but low specificity. With respect to planar imaging, the implementation of single-photon emission computed tomography (SPECT) has allowed increased image contrast and more accurate tracer localization. AREAS COVERED: Recent technological innovations in the field of BS are treated, with a particular focus on multi-field-of-view devices allowing to cover the entire scan length with a 3D acquisition (WB-SPECT/CT)...
August 25, 2023: Expert Review of Medical Devices
https://read.qxmd.com/read/37592454/first-clinical-experience-of-a-ring-configured-cadmium-zinc-telluride-camera-a-comparative-study-versus-conventional-gamma-camera-systems
#36
JOURNAL ARTICLE
Irma Cerić Andelius, David Minarik, Eva Persson, Henrik Mosén, Kristian Valind, Elin Trägårdh, Jenny Oddstig
BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process. METHOD: Seventy-six patients (bone-, cardiac- and lung scan) were scanned on a conventional gamma camera (planar and/or single-photon emission computed tomography [SPECT]/SPECT-CT) used in clinical routine and on the ring-configurated CZT camera Starguide (GE Healthcare)...
August 17, 2023: Clinical Physiology and Functional Imaging
https://read.qxmd.com/read/37592058/the-incremental-value-of-coronary-artery-calcium-score-in-predicting-long-term-prognosis-and-defining-the-warranty-period-of-normal-adenosine-stress-only-myocardial-perfusion-imaging-using-czt-spect
#37
JOURNAL ARTICLE
Mandy Kamerman, Joris D van Dijk, Jorik R Timmer, Jan Paul Ottervanger, Siert Knollema, Pieter L Jager, Mohamed Mouden
BACKGROUND: Normal stress-only (SO) myocardial perfusion imaging (MPI) using SPECT reduces imaging time and radiation dose with a good prognosis. However, the long-term prognostic value of combining coronary artery calcium score (CACS) with SO MPI to determine the warranty period remains unknown. Hence, we assessed the incremental prognostic value of CACS and its impact on the warranty period of normal SO MPI using SPECT. METHODS: We retrospectively included 1375 symptomatic patients without a history of coronary artery disease (CAD) and a normal SO MPI using adenosine who underwent simultaneous CAC scoring...
August 17, 2023: Journal of Nuclear Cardiology
https://read.qxmd.com/read/37535108/exploring-coronary-microvascular-function-by-quantitative-czt-spect-a-small-step-or-giant-leap-for-inoca-patients
#38
EDITORIAL
Adriana D'Antonio, Teresa Mannarino
No abstract text is available yet for this article.
August 3, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37522931/quantitative-analysis-of-99m-tc-pertechnetate-thyroid-uptake-with-a-large-field-czt-gamma-camera-feasibility-and-comparison-between-spect-ct-and-planar-acquisitions
#39
JOURNAL ARTICLE
Benjamin Serrano, Régis Amblard, Tiffany Beaumont, Florent Hugonnet, Matthieu Dietz, Frédéric Berthier, Nicolas Garnier, Rémy Villeneuve, Valérie Nataf, François Mocquot, Christopher Montemagno, Marc Faraggi, Benoît Paulmier
PURPOSE: The main objective of this study was to evaluate the ability of a large field Cadmium Zinc Telluride (CZT) camera to estimate thyroid uptake (TU) on single photon emission computed tomography (SPECT) images with and without attenuation correction (Tomo-AC and Tomo-NoAC) compared with Planar acquisition in a series of 23 consecutive patients. The secondary objective was to determine radiation doses for the tracer administration and for the additional Computed Tomography (CT) scan...
July 31, 2023: EJNMMI Physics
https://read.qxmd.com/read/37491508/spect-myocardial-blood-flow-quantitation-for-the-detection-of-angiographic-stenoses-with-cardiac-dedicated-czt-spect
#40
JOURNAL ARTICLE
Jie Zhang, Jian Xie, Muwei Li, Wei Fang, Bailing Hsu
PURPOSE: CZT SPECT with the enhanced imaging characteristic facilitates SPECT myocardial blood flow (MBF) quantitation moving toward a clinical utility to uncover myocardial ischemia. The purpose of this study was to investigate the diagnostic performance of stress MBF, myocardial flow reserve (MFR) and myocardial flow capacity (MFC) derived from CZT SPECT in the detection of coronary artery disease (CAD). METHODS: One-hundred and eighty patients underwent two-day rest/adenosine-stress scans for SPECT MBF quantitation...
July 25, 2023: Journal of Nuclear Cardiology
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